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- References [110]
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- Product number
- 11049-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11049-1-AP, RRID:AB_2140649
- Product name
- MEK1/2 antibody
- Antibody type
- Polyclonal
- Description
- MEK1/2 antibody (Cat. #11049-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references INHBA Promotes the Progression of Gastric Cancer by Activating MAPK Signaling Pathway via Targeting ITGA6.
CircRNA-encoded RIPK1-98 protein drives lung adenocarcinoma progression.
GLUD1 supports ovarian cancer progression by counteracting anoikis via ARAF/MEK/ERK signaling.
STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma.
The P7 peptide antagonizes bFGF-induced malignant behaviors of ovarian cancer by inhibiting MEK/ERK signaling pathway.
L1TD1 promotes colorectal mucinous adenocarcinoma progression by enhancing ABCC3 mRNA stability.
HIF-1α/Netrin-4 Axis Mediates RIPC-Induced Angiogenesis and Neurogenesis After Ischemic Stroke.
High-throughput screening of EGFR/Ca(2+) signaling modulators in cardiac hypertrophy using a tetrahedral DNA nanostructure-based hESC platform.
HOXB7 drives bladder cancer progression via H-Ras/ERK signaling: a potential therapeutic target and prognostic biomarker.
Cancer-associated fibroblasts regulate mitochondrial metabolism and inhibit chemosensitivity via ANGPTL4-IQGAP1 axis in prostate cancer.
Alpha-enolase promotes progression of acute myeloid leukemia via MAPK/ERK signaling pathway.
Naringenin: A potential therapeutic agent for modulating angiogenesis and immune response in hepatocellular carcinoma.
Bisphenol A promotes OSCC progression via GABBR1-mediated MAPK signaling and macrophage polarization: A network toxicology based study.
Bioactive Silk Sericin/Bioceramic Nerve Guidance Conduit for Effective Repair of Long-Gap Transected Peripheral Nerve Injury through Regulating Schwann Cells.
GPR30-mediated the MEK/ERK signaling pathway promotes porcine oocyte maturation and development.
Assessing cardiac insufficiency risks of aflatoxin B1 through network toxicology and molecular docking analyses.
Rg1-preconditioned adipose-derived mesenchymal stromal cells alleviate colitis via exosome-mediated Inhibition of macrophage glycolysis through RAS signaling.
Integrated analysis of Corylin from Psoralea Corylifolia inhibiting osteoporosis via MAPK pathway.
ShenJiaoLingCao decoction ameliorates cyclophosphamide-induced splenic injury and immunosuppression via the inhibition of MEK/ERK signaling pathway activity and modulation of amino acid metabolism.
LDH nanoparticles-doped cellulose nanofiber scaffolds with aligned microchannels direct high-efficiency neural regeneration and organized neural circuit remodeling through RhoA/Rock/Myosin II pathway.
N-terminal domain of CTRP9 promotes cardiac fibroblast activation in myocardial infarction via Rap1/Mek/Erk pathway.
Bisphenol A exposure enhances proliferation and tumorigenesis of papillary thyroid carcinoma through ROS generation and activation of NOX4 signaling pathways.
Exosomes derived from myelodysplastic syndromes cells induce IL-1β production from macrophages to promote disease progress.
EFNA1 promotes the tumorigenesis and metastasis of cervical cancer by phosphorylation pathway and epithelial-mesenchymal transition.
GCLM lactylation mediated by ACAT2 promotes ferroptosis resistance in KRAS(G12D)-mutant cancer.
PELI2 inhibits colorectal cancer development through MAPK signaling pathway.
BRD9 promotes the malignant phenotype of thyroid cancer by activating the MAPK/ERK pathway.
Downregulation of miR-27a-3p induces endothelial injury and senescence and its significance in the development of coronary heart disease.
The KSR1/MEK/ERK signaling pathway promotes the progression of intrauterine adhesions.
Targeting LINC02320 prevents colorectal cancer growth via GRB7-dependent inhibition of MAPK signaling pathway.
Vitamin K-dependent gamma-carboxyglutamic acid protein 1 promotes pancreatic ductal adenocarcinoma progression through stabilizing oncoprotein KRAS and tyrosine kinase receptor EGFR.
Design and Synthesis of Novel MEK Inhibitors for the Treatment of Solid Tumors.
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
ANLN promotes head and neck squamous cell carcinoma progression by upregulating PD-L1 via the ERK-MAPK pathway.
Extracellular vesicle-mediated gene therapy targets BRAF(V600E)-mutant colorectal cancer by inhibiting the MEK1/2-ERK1/2 pathway.
Bispecific antibody simultaneously targeting AGR2 and PD1 mediates cytotoxic T-cell-induced antitumor response in AGR2-dependent manner and inhibits AGR2-induced PDL1 upregulation.
RhoE downregulation leads to enhanced cholesterol biosynthesis and sorafenib resistance in hepatocellular carcinoma.
A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway.
CYP8B1 inhibits hepatocellular carcinoma progression by repressing PAK4 transcription through inhibition of nuclear translocation of u-STAT1.
E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent manner.
DDX18 promotes growth and metastasis of hepatocellular carcinoma via activating EMT and MAPK signaling.
Construction of lactylation (LA) risk signature in prostate cancer based on 4D fast DIA L-lactated quantitative genomics.
Cinobufacini Inhibits Survival and Metastasis of Hepatocellular Carcinoma via c-Met Signaling Pathway.
tRF-34-P4R8YP9LON4VHM Promotes Hepatocellular Carcinoma Progression and Tumour Cell-Induced Angiogenesis via the MEK/ERK Pathway.
Phosphorylation of POU3F3 Mediated Nuclear Translocation Promotes Proliferation in Non-Small Cell Lung Cancer through Accelerating ATP5PF Transcription and ATP Production.
NCAPH promotes glucose metabolism reprogramming and cell stemness in ovarian cancer cells through the MEK/ERK/PD-L1 pathway.
Macropinocytosis regulates cytokine expression through Erk signaling in LPS-stimulated macrophages.
Dual role of CD73 as a signaling molecule and adenosine-generating enzyme in colorectal cancer progression and immune evasion.
CRABP2 promotes cell migration and invasion by activating PI3K/AKT and MAPK signalling pathways via upregulating LAMB3 in prostate cancer.
Design, synthesis, and biological evaluation of naphthalene imidazo[1,2-b]pyridazine hybrid derivatives as VEGFR selective inhibitors.
Dayuan Yin alleviates symptoms of HCoV-229E-induced pneumonia and modulates the Ras/Raf1/MEK/ERK pathway.
Unveiling the role of PYGB in pancreatic cancer: a novel diagnostic biomarker and gene therapy target.
A specific super-enhancer actuated by berberine regulates EGFR-mediated RAS-RAF1-MEK1/2-ERK1/2 pathway to induce nasopharyngeal carcinoma autophagy.
Multiomic analysis of monocyte-derived alveolar macrophages in idiopathic pulmonary fibrosis.
Intracellular magnetic hyperthermia reverses sorafenib resistance in hepatocellular carcinoma through its action on signaling pathways.
SHED-exos promote saliva secretion by suppressing p-ERK1/2-mediated apoptosis in glandular cells.
Integration analysis of cell division cycle-associated family genes revealed potential mechanisms of gliomagenesis and constructed an artificial intelligence-driven prognostic signature.
RGD-p21Ras-scFv expressed prokaryotically on a pilot scale inhibits ras-driven colorectal cancer growth by blocking p21Ras-GTP.
Helicobacter pylori CagA-mediated ether lipid biosynthesis promotes ferroptosis susceptibility in gastric cancer.
Multiomics analysis reveals metabolic subtypes and identifies diacylglycerol kinase α (DGKA) as a potential therapeutic target for intrahepatic cholangiocarcinoma.
Downregulation of microRNA‑221‑3p promotes angiogenesis of lipoprotein(a)‑injured endothelial progenitor cells by targeting silent information regulator 1 to activate the RAF/MEK/ERK signaling pathway.
Quercetin inhibits malignant progression of high metastatic advanced colon cancer in hypoxia via suppressing ROS and PI3K/AKT pathway.
An anti-RAGE chimeric antibody alleviates CCl(4)-induced liver fibrosis via RAGE/NF-kB pathway in mice.
NRF3 suppresses the malignant progression of TNBC by promoting M1 polarization of macrophages via ROS/HMGB1 axis.
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells.
HBV precore G1896A mutation promotes growth of hepatocellular carcinoma cells by activating ERK/MAPK pathway.
Primary cilium-mediated signaling cascade suppresses age-related biliary fibrosis.
N6-Methyladenosine-Mediated Up-Regulation of FZD10 Regulates Liver Cancer Stem Cells' Properties and Lenvatinib Resistance Through WNT/β-Catenin and Hippo Signaling Pathways.
TATA-box-binding protein-associated factor 15 is a novel biomarker that promotes cell proliferation and migration in gastrointestinal stromal tumor.
An unconventional cancer-promoting function of methamphetamine in hepatocellular carcinoma.
Chitosan targets PI3K/Akt/FoxO3a axis to up-regulate FAM172A and suppress MAPK/ERK pathway to exert anti-tumor effect in osteosarcoma.
Exercise-induced endothelial Mecp2 lactylation suppresses atherosclerosis via the Ereg/MAPK signalling pathway.
BEST1 Positive Monocytes in Circulation: Visualize Intratumoral Crosstalk between Cancer Cells and Monocytes.
HPIP is an essential scaffolding protein running through the EGFR-RAS-ERK pathway and drives tumorigenesis.
HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
Targeting CXCR1 alleviates hyperoxia-induced lung injury through promoting glutamine metabolism.
Fibronectin promotes tumor angiogenesis and progression of non-small-cell lung cancer by elevating WISP3 expression via FAK/MAPK/ HIF-1α axis and activating wnt signaling pathway.
Promotion of the genipin crosslinked chitosan-fiber hydrogel loaded with sustained release of clemastine fumarate in diabetic wound repair.
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Gelatin methacryloyl (GelMA) loaded with concentrated hypoxic pretreated adipose-derived mesenchymal stem cells(ADSCs) conditioned medium promotes wound healing and vascular regeneration in aged skin.
PLX8394, a RAF inhibitor, inhibits enterovirus 71 replication by blocking RAF/MEK/ERK signaling.
Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling.
TAF15 promotes cell proliferation, migration and invasion of gastric cancer via activation of the RAF1/MEK/ERK signalling pathway.
ETV6 Regulates Hemin-Induced Erythroid Differentiation of K562 Cells through Mediating the Raf/MEK/ERK Pathway.
LAMC1-mediated preadipocytes differentiation promoted peritoneum pre-metastatic niche formation and gastric cancer metastasis.
METTL3 Facilitates Tumor Progression by COL12A1/MAPK Signaling Pathway in Esophageal Squamous Cell Carcinoma.
AHSA1 Promotes Proliferation and EMT by Regulating ERK/CALD1 Axis in Hepatocellular Carcinoma.
Combination of RSK inhibitor LJH-685 and FLT3 inhibitor FF-10101 promoted apoptosis and proliferation inhibition of AML cell lines.
Effect of propiconazole on neutrophil extracellular traps formation: Assessing the role of autophagy.
Exosomal DNAJB11 promotes the development of pancreatic cancer by modulating the EGFR/MAPK pathway.
Sanggenon C Suppresses Tumorigenesis of Gastric Cancer by Blocking ERK-Drp1-Mediated Mitochondrial Fission.
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway.
ZFP281-BRCA2 prevents R-loop accumulation during DNA replication.
Near-Infrared Light-Responsive Nanoinhibitors for Tumor Suppression through Targeting and Regulating Anion Channels.
AKTs do not translocate to the nucleus upon stimulation but AKT3 can constitutively signal from the nuclear envelope.
Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways.
miR-34a-5p functions as a tumor suppressor in head and neck squamous cell cancer progression by targeting Flotillin-2.
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Myrtenol improves brain damage and promotes angiogenesis in rats with cerebral infarction by activating the ERK1/2 signalling pathway.
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Tubeimoside I Inhibits Cell Proliferation and Induces a Partly Disrupted and Cytoprotective Autophagy Through Rapidly Hyperactivation of MEK1/2-ERK1/2 Cascade via Promoting PTP1B in Melanoma.
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Down-regulation of the insulin signaling pathway by SHC may correlate with congenital heart disease in Chinese populations.
BPTES inhibits anthrax lethal toxin-induced inflammatory response.
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth.
SOX9 was involved in TKIs resistance in renal cell carcinoma via Raf/MEK/ERK signaling pathway.
hsa-miR-96 up-regulates MAP4K1 and IRS1 and may function as a promising diagnostic marker in human bladder urothelial carcinomas.
Zhou G, Zhang R, Nie L, Si Y, Liu T, Wang J, Han S, Xuan M, Wang J, Yu W
Oncology research 2026;34(3):25
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CircRNA-encoded RIPK1-98 protein drives lung adenocarcinoma progression.
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GLUD1 supports ovarian cancer progression by counteracting anoikis via ARAF/MEK/ERK signaling.
Feng H, Chen Y, Wu G, Zhang Z, Lai H, Yang C, Zhang S, Lin Y, Liu Y, Ye H, Wu S, Cao L
NPJ precision oncology 2026 Mar 5;10(1)
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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma.
Hu H, Zhang H, Han S, Chen J, Xie Y
International journal of molecular medicine 2026 Feb;57(2)
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The P7 peptide antagonizes bFGF-induced malignant behaviors of ovarian cancer by inhibiting MEK/ERK signaling pathway.
Yang Z, Wei W, Nie D, Zhang M, Chen Q
Future science OA 2026 Dec;12(1):2615619
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L1TD1 promotes colorectal mucinous adenocarcinoma progression by enhancing ABCC3 mRNA stability.
He H, Yuan J, Wang H, Chen L, Liu B, Cui Z, Xu Y, Zhang G, Yang H
Oncogene 2026 Apr;45(12):1071-1086
Oncogene 2026 Apr;45(12):1071-1086
HIF-1α/Netrin-4 Axis Mediates RIPC-Induced Angiogenesis and Neurogenesis After Ischemic Stroke.
Feng Z, Liu Z, Tang S, Pan M, Zhu K, Liu Y, Wang C, Yao R, Wei X, Liu H
Journal of cellular and molecular medicine 2026 Apr;30(7):e71121
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High-throughput screening of EGFR/Ca(2+) signaling modulators in cardiac hypertrophy using a tetrahedral DNA nanostructure-based hESC platform.
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HOXB7 drives bladder cancer progression via H-Ras/ERK signaling: a potential therapeutic target and prognostic biomarker.
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Frontiers in oncology 2025;15:1645803
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Cancer-associated fibroblasts regulate mitochondrial metabolism and inhibit chemosensitivity via ANGPTL4-IQGAP1 axis in prostate cancer.
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Journal of advanced research 2025 Sep;75:663-678
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Alpha-enolase promotes progression of acute myeloid leukemia via MAPK/ERK signaling pathway.
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Naringenin: A potential therapeutic agent for modulating angiogenesis and immune response in hepatocellular carcinoma.
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Bisphenol A promotes OSCC progression via GABBR1-mediated MAPK signaling and macrophage polarization: A network toxicology based study.
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Integrated analysis of Corylin from Psoralea Corylifolia inhibiting osteoporosis via MAPK pathway.
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Scientific reports 2025 Nov 19;15(1):40724
Scientific reports 2025 Nov 19;15(1):40724
ShenJiaoLingCao decoction ameliorates cyclophosphamide-induced splenic injury and immunosuppression via the inhibition of MEK/ERK signaling pathway activity and modulation of amino acid metabolism.
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LDH nanoparticles-doped cellulose nanofiber scaffolds with aligned microchannels direct high-efficiency neural regeneration and organized neural circuit remodeling through RhoA/Rock/Myosin II pathway.
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Biomaterials 2025 Mar;314:122873
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N-terminal domain of CTRP9 promotes cardiac fibroblast activation in myocardial infarction via Rap1/Mek/Erk pathway.
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Journal of translational medicine 2025 Mar 10;23(1):300
Journal of translational medicine 2025 Mar 10;23(1):300
Bisphenol A exposure enhances proliferation and tumorigenesis of papillary thyroid carcinoma through ROS generation and activation of NOX4 signaling pathways.
Wang Y, Su X, Wang Q, Zhang L, Yu Y, Zhao Y, Liu Z
Ecotoxicology and environmental safety 2025 Mar 1;292:117946
Ecotoxicology and environmental safety 2025 Mar 1;292:117946
Exosomes derived from myelodysplastic syndromes cells induce IL-1β production from macrophages to promote disease progress.
Li P, Guan D, Li S, Deng J, Zhang H, Liu X, Chen X, Xu Z, Wang H, Ren F
Cytokine 2025 Jun;190:156924
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EFNA1 promotes the tumorigenesis and metastasis of cervical cancer by phosphorylation pathway and epithelial-mesenchymal transition.
Dong X, Chen X, Xue M, Zhang Y, Jiang P
Acta histochemica 2025 Jun;127(2):152236
Acta histochemica 2025 Jun;127(2):152236
GCLM lactylation mediated by ACAT2 promotes ferroptosis resistance in KRAS(G12D)-mutant cancer.
Chen Y, Yan Q, Ruan S, Cui J, Li Z, Zhang Z, Yang J, Fang J, Liu S, Huang S, Hou B, Zhang C
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PELI2 inhibits colorectal cancer development through MAPK signaling pathway.
Liu J, Hu S, Zhao L, Yang Y, Wu G, Duan Y, Ma X, Wang P, Zhang Z, Zong H
Molecular medicine (Cambridge, Mass.) 2025 Jun 12;31(1):235
Molecular medicine (Cambridge, Mass.) 2025 Jun 12;31(1):235
BRD9 promotes the malignant phenotype of thyroid cancer by activating the MAPK/ERK pathway.
Deng Y, Li Y, Cao H
Anti-cancer drugs 2025 Jun 1;36(5):359-373
Anti-cancer drugs 2025 Jun 1;36(5):359-373
Downregulation of miR-27a-3p induces endothelial injury and senescence and its significance in the development of coronary heart disease.
Song CY, Huang HZ, Yan TT, Cui CX, Wu HY, Chen J, Peng JH, Chen NY, Tang J, Pan SL
Cellular signalling 2025 Jul;131:111759
Cellular signalling 2025 Jul;131:111759
The KSR1/MEK/ERK signaling pathway promotes the progression of intrauterine adhesions.
Wu S, Chen Q, Yang X, Zhang L, Huang X, Huang J, Wu J, Sun C, Zhang W, Wang J
Cellular signalling 2025 Jul;131:111730
Cellular signalling 2025 Jul;131:111730
Targeting LINC02320 prevents colorectal cancer growth via GRB7-dependent inhibition of MAPK signaling pathway.
Zhang L, Chen H, Yang Y, Zhao L, Xie H, Li P, Lv X, He L, Liu N, Liu B
Cellular & molecular biology letters 2025 Jul 21;30(1):86
Cellular & molecular biology letters 2025 Jul 21;30(1):86
Vitamin K-dependent gamma-carboxyglutamic acid protein 1 promotes pancreatic ductal adenocarcinoma progression through stabilizing oncoprotein KRAS and tyrosine kinase receptor EGFR.
Wu Z, Ye Q, Zhang S, Hu LP, Wang XQ, Yao LL, Zhu L, Xiao SY, Duan ZH, Zhang XL, Jiang SH, Zhang ZG, Liu DJ, Li DX, Yang XM
Clinical and translational medicine 2025 Jan;15(1):e70191
Clinical and translational medicine 2025 Jan;15(1):e70191
Design and Synthesis of Novel MEK Inhibitors for the Treatment of Solid Tumors.
Zeng J, Luo Z, Zhao T, Xia C, Liu F, Li N, Qu L, Wang C
Chemical biology & drug design 2025 Feb;105(2):e70067
Chemical biology & drug design 2025 Feb;105(2):e70067
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Wang M, Yang S, Li X, Zheng Y, Bai Y, Luo W, Zhu G, Chang J, Zhu B
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
ANLN promotes head and neck squamous cell carcinoma progression by upregulating PD-L1 via the ERK-MAPK pathway.
Wang L, Wang J, Wang N, Wang X, Song M, Zhou Y, Wang Z, Meng H, Guo E, Miao S
iScience 2025 Feb 21;28(2):111633
iScience 2025 Feb 21;28(2):111633
Extracellular vesicle-mediated gene therapy targets BRAF(V600E)-mutant colorectal cancer by inhibiting the MEK1/2-ERK1/2 pathway.
Wang D, Wang L, Zhang W, Xu K, Chen L, Guo Z, Wu K, Huang D, Zhao Y, Yao M, Zheng L, Ye C, Ran J, Zhou W, Liu X, Xu J
Journal of nanobiotechnology 2025 Feb 20;23(1):129
Journal of nanobiotechnology 2025 Feb 20;23(1):129
Bispecific antibody simultaneously targeting AGR2 and PD1 mediates cytotoxic T-cell-induced antitumor response in AGR2-dependent manner and inhibits AGR2-induced PDL1 upregulation.
Roy D, He Y, Wang Y, Xu P, Jin B, Xiao H, Li D, Zhao B
Scientific reports 2025 Feb 19;15(1):6015
Scientific reports 2025 Feb 19;15(1):6015
RhoE downregulation leads to enhanced cholesterol biosynthesis and sorafenib resistance in hepatocellular carcinoma.
Feng J, Ye L, Chen C, Zhu Y, Liu R, Yu H, Lu L, Gong K, Li W
The Journal of biological chemistry 2025 Dec;301(12):110918
The Journal of biological chemistry 2025 Dec;301(12):110918
A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway.
Zhu C, Zhang M, Yang W, Gao A, Yu X, Su X, Chen R, Guo M
Epigenetics 2025 Dec;20(1):2512764
Epigenetics 2025 Dec;20(1):2512764
CYP8B1 inhibits hepatocellular carcinoma progression by repressing PAK4 transcription through inhibition of nuclear translocation of u-STAT1.
Xu L, Xiong L, Yuan J, Chen Y, Chen F, Wang S, Xu X
Cell death & disease 2025 Dec 31;17(1):172
Cell death & disease 2025 Dec 31;17(1):172
E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent manner.
Li J, Chen Y, Wang J, Liu L, Qadir J, Xie D, Wan X, Luo Y, Xian J, Ye T
Journal of experimental & clinical cancer research : CR 2025 Aug 30;44(1):261
Journal of experimental & clinical cancer research : CR 2025 Aug 30;44(1):261
DDX18 promotes growth and metastasis of hepatocellular carcinoma via activating EMT and MAPK signaling.
Xu X, Yu X, Zhang N, Wang F, Chen Z
Journal of gastrointestinal oncology 2025 Aug 30;16(4):1622-1634
Journal of gastrointestinal oncology 2025 Aug 30;16(4):1622-1634
Construction of lactylation (LA) risk signature in prostate cancer based on 4D fast DIA L-lactated quantitative genomics.
Zou F, Jin Y, Zhang Z, Zhang Y, Wang M, Zhu F, Qiu J, Ye H, Fu Y, Ping H
Journal of translational medicine 2025 Aug 28;23(1):967
Journal of translational medicine 2025 Aug 28;23(1):967
Cinobufacini Inhibits Survival and Metastasis of Hepatocellular Carcinoma via c-Met Signaling Pathway.
Ma YN, Jiang XM, Hu XQ, Wang L, Gao JJ, Liu H, Qi FH, Song PP, Tang W
Chinese journal of integrative medicine 2025 Apr;31(4):311-325
Chinese journal of integrative medicine 2025 Apr;31(4):311-325
tRF-34-P4R8YP9LON4VHM Promotes Hepatocellular Carcinoma Progression and Tumour Cell-Induced Angiogenesis via the MEK/ERK Pathway.
Xu T, Hua H, Song F, Zhang N, Gao C, Chen Z
Journal of cellular and molecular medicine 2025 Apr;29(8):e70560
Journal of cellular and molecular medicine 2025 Apr;29(8):e70560
Phosphorylation of POU3F3 Mediated Nuclear Translocation Promotes Proliferation in Non-Small Cell Lung Cancer through Accelerating ATP5PF Transcription and ATP Production.
Zeng QG, Li L, Chang T, Sun Y, Zheng B, Xue LN, Liu CL, Li XQ, Huang RT, Gu JX, An ZR, Yao HT, Zhou DY, Fan J, Dai Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2411503
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2411503
NCAPH promotes glucose metabolism reprogramming and cell stemness in ovarian cancer cells through the MEK/ERK/PD-L1 pathway.
Qi Y, Wang A, Chen S, Chen W
Journal of ovarian research 2025 Apr 21;18(1):81
Journal of ovarian research 2025 Apr 21;18(1):81
Macropinocytosis regulates cytokine expression through Erk signaling in LPS-stimulated macrophages.
Wang L, Li Y, He Y, Fang Y, Mimuro H, Midgley AC, Yoshida S
Cell structure and function 2025 Apr 18;50(1):103-113
Cell structure and function 2025 Apr 18;50(1):103-113
Dual role of CD73 as a signaling molecule and adenosine-generating enzyme in colorectal cancer progression and immune evasion.
Lian W, Jiang D, Lin W, Jiang M, Zhang Y, Wang H, Zhao L
International journal of biological sciences 2024;20(1):137-151
International journal of biological sciences 2024;20(1):137-151
CRABP2 promotes cell migration and invasion by activating PI3K/AKT and MAPK signalling pathways via upregulating LAMB3 in prostate cancer.
Wang R, Liao Z, Liu C, Yu S, Xiang K, Wu T, Feng J, Ding S, Yu T, Cheng G, Li S
Journal of biochemistry 2024 Sep 30;176(4):313-324
Journal of biochemistry 2024 Sep 30;176(4):313-324
Design, synthesis, and biological evaluation of naphthalene imidazo[1,2-b]pyridazine hybrid derivatives as VEGFR selective inhibitors.
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Cancer communications (London, England) 2024 Feb;44(2):226-250
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Pharmaceutical science advances 2024 Dec;2:100057
Pharmaceutical science advances 2024 Dec;2:100057
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Cancer biology & therapy 2024 Dec 31;25(1):2416221
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Virologica Sinica 2023 Oct;38(5):680-689
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Journal of cellular physiology 2023 Nov;238(11):2600-2611
Journal of cellular physiology 2023 Nov;238(11):2600-2611
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Gastroenterology 2023 May;164(6):990-1005
Gastroenterology 2023 May;164(6):990-1005
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World journal of gastroenterology 2023 May 21;29(19):2932-2949
World journal of gastroenterology 2023 May 21;29(19):2932-2949
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Life science alliance 2023 Mar;6(3)
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International journal of molecular sciences 2023 Apr 30;24(9)
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Molecular medicine reports 2012 Jan;5(1):260-5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MEK2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MEK2. This antibody recognizes human,mouse,rat antigen. The MEK2 antibody has been validated for the following applications: ELISA, WB analysis.
