Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx011107 - Provider product page
- Provider
- Abbexa
- Product name
- Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) Antibody
- Antibody type
- Monoclonal
- Description
- MAP2K2, also called MEK2, it is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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