Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- RB-02-0017-200 - Provider product page
- Provider
- RayBiotech, Inc.
- Product name
- Rabbit anti-Human Stat2 (p690) (Phosph)
- Antibody type
- Polyclonal
- Antigen
- The imunogen was synthetic peptide.
- Description
- Stat2 is one of seven members of the Signal transducer and activators of transcription (Stats) family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Stat2 is a latent transcription factor that functions both as a signal transducer in the cytoplasm and an activator of transcription in the nucleusStat2 is phosphorylated at Tyr690 by JAKs. Additionally, upon activation, Stat2 will form a multi-protein DNA-binding complex with Stat-1 and ISGF3?p48. This activation subsequently allows the complex to translocate to the nucleus & bind specific enhancer elements. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Biotin
- Antigen sequence
This antibody was produced from a r
abbit immunized with the immunogen.
The IgG fraction was purified from
rabbit serum followed by Protein A
/G affinity chromatography.- Isotype
- IgG
- Vial size
- 200 µg
- Handling
- Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1x PBS to a final concentration of 1 mg/ml.
No comments: Submit comment
No validations: Submit validation data