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Protein structure
STAT2
Signal transducer and activator of transcription 2STAT113
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44. [provided by RefSeq, Aug 2020]
Top validated antibodies |
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| Invitrogen Antibodies |  44-362G |
2 references | Polyclonal |
WB
ICC
IP
IHC
FC
ChIP
OA
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| Proteintech Group | 16674-1-AP |
17 references | Polyclonal |
WB
EL
IP
IHC
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| GeneTex | GTX103117 |
3 references | Polyclonal |
WB
IP
IHC
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| LSBio | LS-C406209 |
Polyclonal |
WB
EL
IHC
|
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| Cell Signaling Technology, Inc | 72604 |
Monoclonal |
WB
ICC
IP
FC
ChIP
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