Antibody data
- Antibody Data
- Antigen structure
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- Product number
- 624502 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#624502, RRID:AB_2198452
- Product name
- Purified anti-STAT2
- Antibody type
- Polyclonal
- Antigen
- Peptide mapping to the carboxy terminus of human STAT2
- Description
- STAT2, a 113 kD member of the STAT (signal transducer and activators of transcription) protein family, is phosphorylated in response to interferon alpha receptor signaling by Janus kinase I. Phosphorylation of STAT 2 induces nuclear translocation to activate transcription. STAT2 is highly expressed in the skin and thymus. STAT 2 forms complex with STAT1 and p48 to activate transcription and does not bind DNA directly. STAT 3 interacts with interferon regulatory factor 9, interferon alpha receptor, STAT 1, p48, and CREB binding protein. The Poly6245 antibody recognizes the C-terminal region of human STAT2 and has been shown to be useful for Western blotting, immunoprecipitation, and immunohistochemistry.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 200 µl
- Storage
- The antibody solution should be stored undiluted at 4°C. DO NOT FREEZE.
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