624502

antibody from BioLegend

Targeting: STAT2 STAT113

Western blot (Data presented on provider website)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

624502

Provider

BioLegend

Proper citation

BioLegend Cat#624502, RRID:AB_2198452

Product name

Purified anti-STAT2

Antibody type

Polyclonal

Antigen

Peptide mapping to the carboxy terminus of human STAT2

Description

STAT2, a 113 kD member of the STAT (signal transducer and activators of transcription) protein family, is phosphorylated in response to interferon alpha receptor signaling by Janus kinase I. Phosphorylation of STAT 2 induces nuclear translocation to activate transcription. STAT2 is highly expressed in the skin and thymus. STAT 2 forms complex with STAT1 and p48 to activate transcription and does not bind DNA directly. STAT 3 interacts with interferon regulatory factor 9, interferon alpha receptor, STAT 1, p48, and CREB binding protein. The Poly6245 antibody recognizes the C-terminal region of human STAT2 and has been shown to be useful for Western blotting, immunoprecipitation, and immunohistochemistry.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Vial size

200 µl

Storage

The antibody solution should be stored undiluted at 4°C. DO NOT FREEZE.