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antibody from Cell Signaling Technology, Inc
Targeting: MTOR
FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
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- Antigen structure
- References [9]
- Comments [0]
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- Product number
- 2972 - Provider product page
- Provider
- Cell Signaling Technology, Inc
- Proper citation
- Cell Signaling Technology Cat#2972, RRID:AB_330978
- Product name
- mTOR Antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Storage
- -20°C
Submitted references Heat shock protein 90 regulates phosphatidylinositol 3-kinase-related protein kinase family proteins together with the RUVBL1/2 and Tel2-containing co-factor complex.
mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.
ER stress inhibits mTORC2 and Akt signaling through GSK-3β-mediated phosphorylation of rictor.
Ankrd26 gene disruption enhances adipogenesis of mouse embryonic fibroblasts.
The association of AMPK with ULK1 regulates autophagy.
A growth stimulus is needed for IGF-1 to induce skeletal muscle hypertrophy in vivo.
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.
Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region.
ARK5 is a tumor invasion-associated factor downstream of Akt signaling.
Izumi N, Yamashita A, Hirano H, Ohno S
Cancer science 2012 Jan;103(1):50-7
Cancer science 2012 Jan;103(1):50-7
mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.
Gao D, Inuzuka H, Tan MK, Fukushima H, Locasale JW, Liu P, Wan L, Zhai B, Chin YR, Shaik S, Lyssiotis CA, Gygi SP, Toker A, Cantley LC, Asara JM, Harper JW, Wei W
Molecular cell 2011 Oct 21;44(2):290-303
Molecular cell 2011 Oct 21;44(2):290-303
ER stress inhibits mTORC2 and Akt signaling through GSK-3β-mediated phosphorylation of rictor.
Chen CH, Shaikenov T, Peterson TR, Aimbetov R, Bissenbaev AK, Lee SW, Wu J, Lin HK, Sarbassov dos D
Science signaling 2011 Feb 22;4(161):ra10
Science signaling 2011 Feb 22;4(161):ra10
Ankrd26 gene disruption enhances adipogenesis of mouse embryonic fibroblasts.
Fei Z, Bera TK, Liu X, Xiang L, Pastan I
The Journal of biological chemistry 2011 Aug 5;286(31):27761-8
The Journal of biological chemistry 2011 Aug 5;286(31):27761-8
The association of AMPK with ULK1 regulates autophagy.
Lee JW, Park S, Takahashi Y, Wang HG
PloS one 2010 Nov 3;5(11):e15394
PloS one 2010 Nov 3;5(11):e15394
A growth stimulus is needed for IGF-1 to induce skeletal muscle hypertrophy in vivo.
Shavlakadze T, Chai J, Maley K, Cozens G, Grounds G, Winn N, Rosenthal N, Grounds MD
Journal of cell science 2010 Mar 15;123(Pt 6):960-71
Journal of cell science 2010 Mar 15;123(Pt 6):960-71
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.
Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, Guan JL, Oshiro N, Mizushima N
Molecular biology of the cell 2009 Apr;20(7):1981-91
Molecular biology of the cell 2009 Apr;20(7):1981-91
Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region.
Takahara T, Hara K, Yonezawa K, Sorimachi H, Maeda T
The Journal of biological chemistry 2006 Sep 29;281(39):28605-14
The Journal of biological chemistry 2006 Sep 29;281(39):28605-14
ARK5 is a tumor invasion-associated factor downstream of Akt signaling.
Suzuki A, Lu J, Kusakai G, Kishimoto A, Ogura T, Esumi H
Molecular and cellular biology 2004 Apr;24(8):3526-35
Molecular and cellular biology 2004 Apr;24(8):3526-35
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