Tissue expression
Cell line expression

MTOR

gene product
FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1 
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This kinase is a component of two distinct complexes, mTORC1, which controls protein synthesis, cell growth and proliferation, and mTORC2, which is a regulator of the actin cytoskeleton, and promotes cell survival and cell cycle progression. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Inhibitors of mTOR are used in organ transplants as immunosuppressants, and are being evaluated for their therapeutic potential in SARS-CoV-2 infections. Mutations in this gene are associated with Smith-Kingsmore syndrome and somatic focal cortical dysplasia type II. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Aug 2020]
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1864 antibodies from 53 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
17 antibodies
Invitrogen Antibodies
95 antibodies
Proteintech Group
8 antibodies
Novus Biologicals
74 antibodies
antibodies-online
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Cell Signaling Technology, Inc
12 antibodies
OriGene
72 antibodies
Boster Biological Technology
11 antibodies
LifeSpan BioSciences, Inc.
227 antibodies
NovoPro Bioscience Inc.
5 antibodies
St John's Laboratory
18 antibodies
Abnova Corporation
20 antibodies
Biorbyt
112 antibodies
Enzo Life Sciences
3 antibodies
Cusabio Biotech Co., Ltd
17 antibodies
Acris Antibodies GmbH
45 antibodies
Affinity Biosciences
7 antibodies
Arigo
5 antibodies
Signalway Antibody LLC
4 antibodies
Abgent
13 antibodies
NSJ Bioreagents
2 antibodies
Bioworld Technology, Inc
4 antibodies
Aviva Systems Biology
10 antibodies
ProSci
7 antibodies
R&D Systems
5 antibodies
Bethyl Laboratories
4 antibodies
Wuhan Fine Biotech Co., Ltd.
3 antibodies
HUABIO Research
2 antibodies
Rockland Immunochemicals, Inc.
3 antibodies
SignalChem
2 antibodies
BioLegend
9 antibodies
RabMAbs
10 antibodies
Abbkine Scientific Co.Ltd.
8 antibodies
QED Bioscience
2 antibodies
MyBioSource
12 antibodies
Abbexa
44 antibodies
Leading Biology
13 antibodies
Atlas Antibodies
2 antibodies
Creative Diagnostics
13 antibodies
RayBiotech, Inc.
6 antibodies
EMD Millipore
10 antibodies
GenWay
6 antibodies
FabGennix
3 antibodies
United States Biological
142 antibodies
Spring Bioscience
8 antibodies
MilliporeSigma / Merck KGaA
11 antibodies
Creative Biolabs
43 antibodies
Abiocode, Inc.
2 antibodies
Abbiotec
1 antibody
eBioscience, An Affymetrix Company
2 antibodies
Exalpha Biologicals, Inc.
2 antibodies
CPTAC
9 antibodies