ABIN501014
antibody from antibodies-online
Targeting: MTOR
FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
Reference
Comment
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- Product number
- ABIN501014 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) antibody
- Antibody type
- Polyclonal
- Antigen
- TOR antibody was raised against a 15 amino acid peptide from near the amino terminus ofhuman TOR.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Submitted references Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression.
Integration of growth factor and nutrient signaling: implications for cancer biology.
Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin.
RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs.
Fingar DC, Blenis J
Oncogene 2004 Apr 19;23(18):3151-71
Oncogene 2004 Apr 19;23(18):3151-71
Integration of growth factor and nutrient signaling: implications for cancer biology.
Shamji AF, Nghiem P, Schreiber SL
Molecular cell 2003 Aug;12(2):271-80
Molecular cell 2003 Aug;12(2):271-80
Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin.
Cardenas ME, Zhu D, Heitman J
Current opinion in nephrology and hypertension 1995 Nov;4(6):472-7
Current opinion in nephrology and hypertension 1995 Nov;4(6):472-7
RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs.
Sabatini DM, Erdjument-Bromage H, Lui M, Tempst P, Snyder SH
Cell 1994 Jul 15;78(1):35-43
Cell 1994 Jul 15;78(1):35-43
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of TOR in L1210 cell lysate with AP30931PU-N at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of TOR in L1210 cells with AP30931PU-N at 2 ?g/ml.