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LearnABIN117909
antibody from antibodies-online
Targeting: MTOR
FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations [0]
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- Product number
- ABIN117909 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) (AA 2440-2457), (pSer2448) antibody
- Antibody type
- Polyclonal
- Description
- Immunoaffinity Chromatography using the immunizing peptide after immobilization to a solid phase.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 2440-2457, pSer2448
- Vial size
- 0.1 mg
- Storage
- Store the antibody prior to reconstitution at -20°C. Following reconstitution the antibody can be stored at 2-8°C for one month or at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references 1550 nm high contrast grating VCSEL.
Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin.
The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif.
Phospholipase D confers rapamycin resistance in human breast cancer cells.
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.
The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase.
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.
The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin.
Predominant nuclear localization of mammalian target of rapamycin in normal and malignant cells in culture.
Chase C, Rao Y, Hofmann W, Chang-Hasnain CJ
Optics express 2010 Jul 19;18(15):15461-6
Optics express 2010 Jul 19;18(15):15461-6
Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin.
Kristof AS, Marks-Konczalik J, Billings E, Moss J
The Journal of biological chemistry 2003 Sep 5;278(36):33637-44
The Journal of biological chemistry 2003 Sep 5;278(36):33637-44
The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif.
Nojima H, Tokunaga C, Eguchi S, Oshiro N, Hidayat S, Yoshino K, Hara K, Tanaka N, Avruch J, Yonezawa K
The Journal of biological chemistry 2003 May 2;278(18):15461-4
The Journal of biological chemistry 2003 May 2;278(18):15461-4
Phospholipase D confers rapamycin resistance in human breast cancer cells.
Chen Y, Zheng Y, Foster DA
Oncogene 2003 Jun 19;22(25):3937-42
Oncogene 2003 Jun 19;22(25):3937-42
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.
Inoki K, Li Y, Zhu T, Wu J, Guan KL
Nature cell biology 2002 Sep;4(9):648-57
Nature cell biology 2002 Sep;4(9):648-57
The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase.
Choi JH, Bertram PG, Drenan R, Carvalho J, Zhou HH, Zheng XF
EMBO reports 2002 Oct;3(10):988-94
EMBO reports 2002 Oct;3(10):988-94
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.
Hudson CC, Liu M, Chiang GG, Otterness DM, Loomis DC, Kaper F, Giaccia AJ, Abraham RT
Molecular and cellular biology 2002 Oct;22(20):7004-14
Molecular and cellular biology 2002 Oct;22(20):7004-14
The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin.
McMahon LP, Choi KM, Lin TA, Abraham RT, Lawrence JC Jr
Molecular and cellular biology 2002 Nov;22(21):7428-38
Molecular and cellular biology 2002 Nov;22(21):7428-38
Predominant nuclear localization of mammalian target of rapamycin in normal and malignant cells in culture.
Zhang X, Shu L, Hosoi H, Murti KG, Houghton PJ
The Journal of biological chemistry 2002 Aug 2;277(31):28127-34
The Journal of biological chemistry 2002 Aug 2;277(31):28127-34
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