ABIN966602

antibody from antibodies-online

Targeting: MTOR FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966602

Provider

antibodies-online

Product name

anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) (pSer2448) antibody

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human mTOR around the phosphorylation site of serine 2448 (T-D-SP-Y-S).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100ug

Concentration

100ug/100ul.

Storage

Store at -20°C/1 year.

References

Submitted references

Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase.

Chiang GG, Abraham RT
The Journal of biological chemistry 2005 Jul 8;280(27):25485-90

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Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase.

Holz MK, Blenis J
The Journal of biological chemistry 2005 Jul 15;280(28):26089-93

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In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.

Mothe-Satney I, Gautier N, Hinault C, Lawrence JC Jr, Van Obberghen E
The Journal of biological chemistry 2004 Oct 8;279(41):42628-37