MB0035

antibody from Bioworld Technology, Inc
Targeting: HDAC3 HD3, KDAC3, RPD3, RPD3-2
Provider product page for MB0035

Antibody data

Product number
MB0035 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HDAC3 monoclonal antibody
Antibody type
Monoclonal
Antigen
Recombinant full length Human HDAC3.
Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation
Reactivity
Human, Mouse, Rat
Host
Mouse
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HDAC3 protein structure - MB0035 shown in red.