PAB13106

antibody from Abnova Corporation

Targeting: BBC3 JFY1, PUMA

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB13106

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB13106, RRID:AB_10550038

Product name

BBC3 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of BBC3.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals.

Han J, Flemington C, Houghton AB, Gu Z, Zambetti GP, Lutz RJ, Zhu L, Chittenden T
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 25;98(20):11318-23

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PUMA, a novel proapoptotic gene, is induced by p53.

Nakano K, Vousden KH
Molecular cell 2001 Mar;7(3):683-94

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PUMA induces the rapid apoptosis of colorectal cancer cells.

Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B
Molecular cell 2001 Mar;7(3):673-82

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of BBC3 expression in K-562 cell lysate with BBC3 polyclonal antibody (Cat # PAB13106) at 2 ug /mL .

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemistry of BBC3 in human breast carcinoma with BBC3 polyclonal antibody (Cat # PAB13106) at 10 ug/mL .

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)