Tissue expression
Cell line expression
Protein structure

BBC3

BCL2 binding component 3
JFY1, PUMA 
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
More gene data

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808 antibodies from 44 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
28 antibodies
PA5-200072Polyclonal
MA5-31994Monoclonal
Proteintech Group
1 antibody
55120-1-AP41Polyclonal
Novus Biologicals
36 antibodies
NBP1-766395Polyclonal
NBP2-67326Monoclonal
GeneTex
11 antibodies
GTX1096754Polyclonal
GTX31671Polyclonal
antibodies-online
213 antibodies
ABIN7315282Polyclonal
ABIN2523475Polyclonal
Acris Antibodies GmbH
23 antibodies
AP11313PU-NPolyclonal
AP30702PU-NPolyclonal
Abgent
14 antibodies
AP1317aPolyclonal
AJ1666a1Monoclonal
Biorbyt
42 antibodies
orb379147Polyclonal
orb1437750Polyclonal
OriGene
21 antibodies
AP11313PU-NPolyclonal
TA306109Polyclonal
NSJ Bioreagents
4 antibodies
F42785Polyclonal
F40032Polyclonal
NovoPro Bioscience Inc.
3 antibodies
134831Polyclonal
114338Polyclonal
Abnova Corporation
16 antibodies
PAB112523Polyclonal
PAB131063Polyclonal
Boster Biological Technology
4 antibodies
A04899-1Polyclonal
M04899Monoclonal
Aviva Systems Biology
6 antibodies
OAAB09482Polyclonal
OAAB10400Polyclonal
HUABIO Research
2 antibodies
ER31215Polyclonal
ET1602-24Monoclonal
bs-1573R3Polyclonal
bsm-52276RMonoclonal
LS-C497865Monoclonal
LS-C9Polyclonal
Cell Signaling Technology, Inc
5 antibodies
74671Polyclonal
98672Monoclonal
Enzo Life Sciences
1 antibody
ADI-905-237-100Polyclonal
St John's Laboratory
4 antibodies
STJ11101945Monoclonal
STJ119319Polyclonal
ProSci
8 antibodies
3043Polyclonal
3041Polyclonal
Aladdin Scientific Corporation
1 antibody
Ab123948Recombinant
Arigo
2 antibodies
ARG54439Polyclonal
ARG54440Polyclonal
Rockland Immunochemicals, Inc.
7 antibodies
600-401-9871Polyclonal
200-301-DV1Monoclonal
RabMAbs
2 antibodies
1652-1Monoclonal
ab33906Monoclonal
Everest Biotech
1 antibody
EB10389Polyclonal
Cusabio Biotech Co., Ltd
8 antibodies
CSB-PA003890Polyclonal
CSB-PA163307Polyclonal
QED Bioscience
2 antibodies
11007Polyclonal
11008Polyclonal
Affinity Biosciences
1 antibody
AF5173Polyclonal
Antibodies.com
1 antibody
A82709Polyclonal
MyBioSource
17 antibodies
MBS9207882Polyclonal
MBS150888Polyclonal
Leading Biology
9 antibodies
APR07168GPolyclonal
APR07167GMonoclonal
United States Biological
87 antibodies
P9198-02LMonoclonal
032437Polyclonal
MilliporeSigma / Merck KGaA
6 antibodies
PRS3043Polyclonal
PRS3041Polyclonal
Abbkine Scientific Co.Ltd.
1 antibody
ABP52286Polyclonal
Bioworld Technology, Inc
1 antibody
BS2922Polyclonal
Abbiotec
6 antibodies
253425Polyclonal
253426Polyclonal
Creative Biolabs
12 antibodies
CBMAB-Ab027-LYRecombinant
CBMAB-P0082-YCRecombinant
RayBiotech, Inc.
5 antibodies
119-12066Polyclonal
119-16348Polyclonal
Abbexa
8 antibodies
abx327163Polyclonal
abx339653Polyclonal
GenWay
5 antibodies
18-001-30064Polyclonal
18-661-15137Polyclonal
Creative Diagnostics
7 antibodies
CPBT-66398RBPolyclonal
DCABH-14690Monoclonal
EMD Millipore
2 antibodies
ABC158Polyclonal
AB10418Polyclonal
eBioscience, An Affymetrix Company
1 antibody
14-6041-82Polyclonal