BBC3

gene product
JFY1, PUMA
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
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Antibodies

 

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Antibodypedia Validation Initiative

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Eligible for validation within AVI
734 antibodies from 38 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
11 antibodies
antibodies-online
213 antibodies
Biorbyt
48 antibodies
Novus Biologicals
28 antibodies
Acris Antibodies GmbH
23 antibodies
Abgent
14 antibodies
OriGene
20 antibodies
NSJ Bioreagents
4 antibodies
Invitrogen Antibodies
15 antibodies
NovoPro Bioscience Inc.
3 antibodies
Abnova Corporation
16 antibodies
Aviva Systems Biology
6 antibodies
Boster Biological Technology
2 antibodies
Rockland Immunochemicals, Inc.
7 antibodies
Cell Signaling Technology, Inc
4 antibodies
Enzo Life Sciences
1 antibody
LifeSpan BioSciences, Inc.
151 antibodies
ProSci
8 antibodies
St John's Laboratory
3 antibodies
Arigo
2 antibodies
RabMAbs
2 antibodies
Proteintech Group
1 antibody
Affinity Biosciences
1 antibody
Antibodies.com
1 antibody
MyBioSource
17 antibodies
Creative Biolabs
1 antibody
Everest Biotech
1 antibody
United States Biological
87 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
Abbiotec
6 antibodies
RayBiotech, Inc.
5 antibodies
GenWay
5 antibodies
Creative Diagnostics
7 antibodies
Sigma-Aldrich
4 antibodies
EMD Millipore
2 antibodies
eBioscience, An Affymetrix Company
1 antibody