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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- ABIN356830 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-BCL2 Binding Component 3 (BBC3) (BH3 Domain), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- BH3 Domain, C-Term
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references PUMA in head and neck cancer.
Bax conformational change is a crucial step for PUMA-mediated apoptosis in human leukemia.
PUMA mediates the apoptotic response to p53 in colorectal cancer cells.
Hoque MO, Begum S, Sommer M, Lee T, Trink B, Ratovitski E, Sidransky D
Cancer letters 2003 Sep 10;199(1):75-81
Cancer letters 2003 Sep 10;199(1):75-81
Bax conformational change is a crucial step for PUMA-mediated apoptosis in human leukemia.
Liu FT, Newland AC, Jia L
Biochemical and biophysical research communications 2003 Oct 24;310(3):956-62
Biochemical and biophysical research communications 2003 Oct 24;310(3):956-62
PUMA mediates the apoptotic response to p53 in colorectal cancer cells.
Yu J, Wang Z, Kinzler KW, Vogelstein B, Zhang L
Proceedings of the National Academy of Sciences of the United States of America 2003 Feb 18;100(4):1931-6
Proceedings of the National Academy of Sciences of the United States of America 2003 Feb 18;100(4):1931-6
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