18934-1-AP

antibody from Proteintech Group

Targeting: NEFH NF-H, NFH

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

18934-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#18934-1-AP, RRID:AB_10640801

Product name

NF-H/NF200 antibody

Antibody type

Polyclonal

Description

NF-H/NF200 antibody (Cat. #18934-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Transsynaptic degeneration of ventral horn motor neurons exists but plays a minor role in lower motor system dysfunction in acute ischemic rats.

Zhang L, Liu J, Liu M
PloS one 2024;19(4):e0298006

---

MG53/GMs/HA-Dex neural scaffold promotes the functional recovery of spinal cord injury by alleviating neuroinflammation.

Li X, Ji R, Duan L, Hao Z, Su Y, Wang H, Guan F, Ma S
International journal of biological macromolecules 2024 May;267(Pt 2):131520

---

Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis.

Liu T, Ma Z, Liu L, Pei Y, Wu Q, Xu S, Liu Y, Ding N, Guan Y, Zhang Y, Chen X
Neural regeneration research 2024 May;19(5):1105-1111

---

Alteration of Neurotrophic Factors and Innervation in Extraocular Muscles of Individuals With Concomitant Esotropia.

Hao J, Wang M, Liu J, Yusufu M, Cao K, Fu J
Investigative ophthalmology & visual science 2024 Mar 5;65(3):1

---

Zein-Based Triple-Drug Nanoparticles to Promote Anti-Inflammatory Responses for Nerve Regeneration after Spinal Cord Injury.

Wang J, Lin Y, Li C, Lei F, Luo H, Jing P, Fu Y, Zhang Z, Wang C, Liu Z, Jiang J, Zhou M, Du X, Liu Z, Zhou X, Sun X, Zhong Z
Advanced healthcare materials 2024 Jul;13(18):e2304261

---

TsMS combined with EA promotes functional recovery and axonal regeneration via mediating the miR-539-5p/Sema3A/PlexinA1 signalling axis in sciatic nerve-injured rats.

Wang X, Hu S, Ouyang S, Pan X, Fu Y, Chen X, Wu S
Neuroscience letters 2024 Feb 28;824:137691

---

The GDNF-gel/HA-Mg conduit promotes the repair of peripheral nerve defects by regulating PPAR-γ/RhoA/ROCK signaling pathway.

Cai Y, Chen Y, Zhang G, Lin Y, Zhang J, Liang J, Lv L, Wang Y, Fang X, Dang X
iScience 2024 Feb 16;27(2):108969

---

Continuous immunosuppression is required for suppressing immune responses to xenografts in non-human primate brains.

Feng S, Zhang T, He Z, Zhang W, Chen Y, Yue C, Jing N
Cell regeneration (London, England) 2024 Apr 7;13(1):8

---

TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction.

Zhang X, Shao J, Wang C, Liu C, Hao H, Li X, An Y, He J, Zhao W, Zhao Y, Kong Y, Jia Z, Wan S, Yuan Y, Zhang H, Zhang H, Du X
Cell reports 2024 Apr 23;43(4):114014

---

Mesenchymal Stem Cell-Derived Exosomes Promote Recovery of The Facial Nerve Injury through Regulating Macrophage M1 and M2 Polarization by Targeting the P38 MAPK/NF-Κb Pathway.

Xue R, Xie M, Wu Z, Wang S, Zhang Y, Han Z, Li C, Tang Q, Wang L, Li D, Wang S, Yang H, Zhao RC
Aging and disease 2024 Apr 1;15(2):851-868

---

BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.

Wei X, Huang C, Chen K, Liu S, Wang M, Yang L, Wang Y
Neurochemical research 2023 Sep;48(9):2687-2700

---

Gut microbiota modulate distal symmetric polyneuropathy in patients with diabetes.

Yang J, Yang X, Wu G, Huang F, Shi X, Wei W, Zhang Y, Zhang H, Cheng L, Yu L, Shang J, Lv Y, Wang X, Zhai R, Li P, Cui B, Fang Y, Deng X, Tang S, Wang L, Yuan Q, Zhao L, Zhang F, Zhang C, Yuan H
Cell metabolism 2023 Sep 5;35(9):1548-1562.e7

---

Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.

Hu S, Wang X, Yang X, Ouyang S, Pan X, Fu Y, Wu S
Neuroscience 2023 Sep 1;527:37-51

---

Fucosyltransferase 9 promotes neuronal differentiation and functional recovery after spinal cord injury by suppressing the activation of Notch signaling.

Chen J, Zeng X, Zhang W, Li G, Zhong H, Xu C, Li X, Lin T
Acta biochimica et biophysica Sinica 2023 Oct 25;55(10):1571-1581

---

Pure platelet-rich plasma promotes semaphorin-3A expression: a novel insight to ameliorate intervertebral disk degeneration in vitro.

Huang J, Lian SL, Han JH, Lu ZC, Ding Y
Journal of orthopaedic surgery and research 2023 Oct 20;18(1):789

---

Blood-nerve barrier enhances chronic postsurgical pain via the HIF-1α/ aquaporin-1 signaling axis.

Wu PZ, Yao J, Meng B, Qin YB, Cao S
BMC anesthesiology 2023 Nov 21;23(1):381

---

Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.

Sun X, Huang LY, Pan HX, Li LJ, Wang L, Pei GQ, Wang Y, Zhang Q, Cheng HX, He CQ, Wei Q
Neural regeneration research 2023 May;18(5):1067-1075

---

A combination of umbilical cord mesenchymal stem cells and monosialotetrahexosy 1 ganglioside alleviates neuroinflammation in traumatic brain injury.

Fang Y, Qiu W, Li X, Jin Q, Yan H, Yu N, Zhao J, Tan Y, Zhao Z
Experimental brain research 2023 Mar;241(3):713-726

---

Motor neurons transplantation alleviates neurofibrogenesis during chronic degeneration by reversibly regulating Schwann cells epithelial-mesenchymal transition.

Wu Z, Ding H, Chen Y, Huang C, Chen X, Hu H, Chen Y, Zhang W, Fang X
Experimental neurology 2023 Jan;359:114272

---

Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury.

Hu Z, Xuan L, Wu T, Jiang N, Liu X, Chang J, Wang T, Han N, Tian X
International immunopharmacology 2023 Jan;114:109616

---

Polydopamine-Decorated PLCL Conduit to Induce Synergetic Effect of Electrical Stimulation and Topological Morphology for Peripheral Nerve Regeneration.

Lu S, Chen W, Wang J, Guo Z, Xiao L, Wei L, Yu J, Yuan Y, Chen W, Bian M, Huang L, Liu Y, Zhang J, Li YL, Jiang LB
Small methods 2023 Feb;7(2):e2200883

---

Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4/MyD88/NF-κB pathway in LPC-induced demyelination.

Wang Y, Sadike D, Huang B, Li P, Wu Q, Jiang N, Fang Y, Song G, Xu L, Wang W, Xie M
Journal of neuroinflammation 2023 Feb 18;20(1):41

---

Dimethyl fumarate ameliorates erectile dysfunction in bilateral cavernous nerve injury rats by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis of nerve via activation of Nrf2/HO-1 signaling pathway.

Song G, Wang J, Liu J, Ruan Y
Redox biology 2023 Dec;68:102938

---

Berberine-loaded MSC-derived sEVs encapsulated in injectable GelMA hydrogel for spinal cord injury repair.

Wang H, Tang Q, Lu Y, Chen C, Zhao YL, Xu T, Yang CW, Chen XQ
International journal of pharmaceutics 2023 Aug 25;643:123283

---

Three-dimensional-printed collagen/chitosan/secretome derived from HUCMSCs scaffolds for efficient neural network reconstruction in canines with traumatic brain injury.

Liu X, Zhang G, Wei P, Zhong L, Chen Y, Zhang J, Chen X, Zhou L
Regenerative biomaterials 2022;9:rbac043

---

ADSCs Combined with Melatonin Promote Peripheral Nerve Regeneration through Autophagy.

Zhang Z, Zhang M, Zhang Z, Sun Y, Wang J, Chang C, Zhu X, Li M, Liu Y
International journal of endocrinology 2022;2022:5861553

---

Inflammasome Inhibition Prevents Motor Deficit and Cerebellar Degeneration Induced by Chronic Methamphetamine Administration.

Ding J, Shen L, Ye Y, Hu S, Ren Z, Liu T, Dai J, Li Z, Wang J, Luo Y, Zhang Q, Zhang X, Qi X, Huang J
Frontiers in molecular neuroscience 2022;15:861340

---

Enhanced effect of combining bone marrow mesenchymal stem cells (BMMSCs) and pulsed electromagnetic fields (PEMF) to promote recovery after spinal cord injury in mice.

Huang L, Sun X, Wang L, Pei G, Wang Y, Zhang Q, Liang Z, Wang D, Fu C, He C, Wei Q
MedComm 2022 Sep;3(3):e160

---

Matrine inhibits the Wnt3a/β-catenin/TCF7L2 signaling pathway in experimental autoimmune encephalomyelitis.

Ma R, Chu Y, Dou M, Jing Y, Zhao X, Li X, Li S, Zhang Y, Wang L, Zhu L
Journal of neuroimmunology 2022 Jun 15;367:577876

---

N-Acetylcysteine alleviates spinal cord injury in rats after early decompression surgery by regulating inflammation and apoptosis.

Guo X, He J, Zhang R, Wang T, Chen J, Wang J, Wang Z, Chang G, Niu Y, Niu Z, Song J
Neurological research 2022 Jul;44(7):605-613

---

Selective activation of cannabinoid receptor-2 reduces white matter injury via PERK signaling in a rat model of traumatic brain injury.

Li L, Luo Q, Shang B, Yang X, Zhang Y, Pan Q, Wu N, Tang W, Du D, Sun X, Jiang L
Experimental neurology 2022 Jan;347:113899

---

Astrocyte-derived sEVs alleviate fibrosis and promote functional recovery after spinal cord injury in rats.

Lu Y, Chen C, Wang H, Du R, Ji J, Xu T, Yang C, Chen X
International immunopharmacology 2022 Dec;113(Pt A):109322

---

Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.

Zhu PP, Hung HF, Batchenkova N, Nixon-Abell J, Henderson J, Zheng P, Renvoisé B, Pang S, Xu CS, Saalfeld S, Funke J, Xie Y, Svara F, Hess HF, Blackstone C
Human molecular genetics 2022 Aug 23;31(16):2779-2795

---

Paeoniflorin Effect of Schwann Cell-Derived Exosomes Ameliorates Dorsal Root Ganglion Neurons Apoptosis through IRE1α Pathway.

Zhu Y, Han S, Li X, Gao Y, Zhu J, Yang X, Xu L
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6079305

---

Icing after eccentric contraction-induced muscle damage perturbs the disappearance of necrotic muscle fibers and phenotypic dynamics of macrophages in mice.

Kawashima M, Kawanishi N, Tominaga T, Suzuki K, Miyazaki A, Nagata I, Miyoshi M, Miyakawa M, Sakuraya T, Sonomura T, Arakawa T
Journal of applied physiology (Bethesda, Md. : 1985) 2021 May 1;130(5):1410-1420

---

Neuregulin-1 converts reactive astrocytes toward oligodendrocyte lineage cells via upregulating the PI3K-AKT-mTOR pathway to repair spinal cord injury.

Ding Z, Dai C, Zhong L, Liu R, Gao W, Zhang H, Yin Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111168

---

Effects of Ginkgo biloba on Early Decompression after Spinal Cord Injury.

Guo X, Wang X, Dong J, Lv W, Zhao S, Jin L, Guo J, Wang M, Cai C, Sun J, Zhou Y, Zhang Q, Chen X, Yang J, Ji R, Xin X, Li M, Li Y, Fan J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6958246

---

Tanshinone IIA Promotes Axonal Regeneration in Rats with Focal Cerebral Ischemia Through the Inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC Signaling.

Wang J, Ni G, Liu Y, Han Y, Jia L, Wang Y
Drug design, development and therapy 2020;14:2775-2787

---

The combined treatment of NAD(+) and atorvastatin ameliorates the development of experimental autoimmune encephalomyelitis in C57BL/6 mice.

Sun H, Wang J, Guo L, Wang Y, Zhang J, Wang J, Quan M, Li B
Journal of neuroimmunology 2020 Oct 24;350:577429

---

A robust TDP-43 knock-in mouse model of ALS.

Huang SL, Wu LS, Lee M, Chang CW, Cheng WC, Fang YS, Chen YR, Cheng PL, Shen CJ
Acta neuropathologica communications 2020 Jan 21;8(1):3

---

Endothelial progenitor cell-conditioned medium promotes angiogenesis and is neuroprotective after spinal cord injury.

Wang T, Fang X, Yin ZS
Neural regeneration research 2018 May;13(5):887-895

---

ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons.

Szewczyk LM, Brozko N, Nagalski A, Röckle I, Werneburg S, Hildebrandt H, Wisniewska MB, Kuznicki J
Glia 2017 Jan;65(1):34-49

---

Treatment with NAD(+) inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice.

Wang J, Zhao C, Kong P, Sun H, Sun Z, Bian G, Sun Y, Guo L
International immunopharmacology 2016 Oct;39:287-294

---

Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response.

Wang J, Zhao C, Kong P, Bian G, Sun Z, Sun Y, Guo L, Li B
Journal of neuroimmunology 2016 Oct 15;299:45-52

---

Tracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: A Link between Stalled Polyribosomes and RNA Granules.

El Fatimy R, Davidovic L, Tremblay S, Jaglin X, Dury A, Robert C, De Koninck P, Khandjian EW
PLoS genetics 2016 Jul;12(7):e1006192

---

Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.

Yin F, Meng C, Lu R, Li L, Zhang Y, Chen H, Qin Y, Guo L
Neural regeneration research 2014 Sep 15;9(18):1665-71

---

Transplantation of mesenchymal stem cells exerts anti-apoptotic effects in adult rats after spinal cord ischemia-reperfusion injury.

Yin F, Guo L, Meng CY, Liu YJ, Lu RF, Li P, Zhou YB
Brain research 2014 May 2;1561:1-10

---

The mechanisms of EGFR in the regulation of axon regeneration.

Xu MF, Zhou H, Hu CY, Liang YQ, Hu L, Chen D
Cell biochemistry and function 2014 Jan;32(1):101-5

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

mouse brain tissue were subjected to SDS PAGE followed by western blot with 18934-1-AP(NEFH antibody) at dilution of 1:500

Sample type

tissue

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human oesophagus cancer using 18934-1-AP(NEFH antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The NF-H antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human NF-H. This antibody recognizes human,mouse,rat antigen. The NF-H antibody has been validated for the following applications: ELISA, WB, IHC analysis.

Appendix

18934-1-AP.pdf

Show more