Tissue expression
Cell line expression
Protein structure
NEFH
Neurofilament heavyNF-H, NFH
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
Top validated antibodies |
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| Novus Biologicals | 3 references | Polyclonal |
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| Proteintech Group | 48 references | Polyclonal |
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| Invitrogen Antibodies | 6 references | Polyclonal |
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| Boster Biological Technology | 24 references | Polyclonal |
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| antibodies-online | 2 references | Monoclonal |
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