Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN393231 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Neurofilament, Heavy Polypeptide (NEFH) (AA 263-364) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 263-364
- Isotype
- IgG
- Antibody clone number
- 2E8
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references A genome-wide association study of carotid atherosclerosis in HIV-infected men.
Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.
Comparative study of CSF neurofilaments in HTLV-1-associated myelopathy/tropical spastic paraparesis and other neurological disorders.
Phosphorylated neurofilament heavy chain is a marker of neurodegeneration in Leber hereditary optic neuropathy (LHON).
Pin1-dependent prolyl isomerization modulates the stress-induced phosphorylation of high molecular weight neurofilament protein.
Shrestha S, Irvin MR, Taylor KD, Wiener HW, Pajewski NM, Haritunians T, Delaney JA, Schambelan M, Polak JF, Arnett DK, Chen YD, Grunfeld C
AIDS (London, England) 2010 Feb 20;24(4):583-92
AIDS (London, England) 2010 Feb 20;24(4):583-92
Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.
Gregório SP, Sallet PC, Do KA, Lin E, Gattaz WF, Dias-Neto E
Psychiatry research 2009 Jan 30;165(1-2):1-9
Psychiatry research 2009 Jan 30;165(1-2):1-9
Comparative study of CSF neurofilaments in HTLV-1-associated myelopathy/tropical spastic paraparesis and other neurological disorders.
Alberti C, Gonzalez J, Maldonado H, Medina F, Barriga A, García L, Kettlun A, Collados L, Puente J, Cartier L, Valenzuela M
AIDS research and human retroviruses 2009 Aug;25(8):803-9
AIDS research and human retroviruses 2009 Aug;25(8):803-9
Phosphorylated neurofilament heavy chain is a marker of neurodegeneration in Leber hereditary optic neuropathy (LHON).
Guy J, Shaw G, Ross-Cisneros FN, Quiros P, Salomao SR, Berezovsky A, Carelli V, Feuer WJ, Sadun AA
Molecular vision 2008;14:2443-50
Molecular vision 2008;14:2443-50
Pin1-dependent prolyl isomerization modulates the stress-induced phosphorylation of high molecular weight neurofilament protein.
Rudrabhatla P, Zheng YL, Amin ND, Kesavapany S, Albers W, Pant HC
The Journal of biological chemistry 2008 Sep 26;283(39):26737-47
The Journal of biological chemistry 2008 Sep 26;283(39):26737-47
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC