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- References [22]
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- Product number
- 16021-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16021-1-AP, RRID:AB_2105788
- Product name
- FBL antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FBL antibody (Cat. #16021-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Oxidative cyclization reagents reveal tryptophan cation-π interactions.
FXR1 stabilizes SNORD63 to regulate blood-tumor barrier permeability through SNORD63 mediated 2'-O-methylation of POU6F1.
U2AF2-SNORA68 promotes triple-negative breast cancer stemness through the translocation of RPL23 from nucleoplasm to nucleolus and c-Myc expression.
Elucidation of the mechanism of nuclear localization of Mexican tetra Neu4 via bipartite nuclear localization signal and less conserved regions.
Nascent ribosomal RNA act as surfactant that suppresses growth of fibrillar centers in nucleolus.
Nucleolus assembly impairment leads to two-cell transcriptional repression via NPM1-mediated PRC2 recruitment.
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
SNORD17-mediated KAT6B mRNA 2'-O-methylation regulates vasculogenic mimicry in glioblastoma cells.
SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway.
Small Nucleolar RNA and C/D Box 15B Regulate the TRIM25/P53 Complex to Promote the Development of Endometrial Cancer.
RNA 2'-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response.
Identification and mapping of post-transcriptional modifications on the HIV-1 antisense transcript Ast in human cells.
C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2'-O-methylation of PARP1.
METTL3 preferentially enhances non-m(6)A translation of epigenetic factors and promotes tumourigenesis.
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
LARP7-Mediated U6 snRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice.
Dual regulation of p53 by the ribosome maturation factor SBDS.
Differential roles of two DDX17 isoforms in the formation of membraneless organelles.
Zika Virus Subverts Stress Granules To Promote and Restrict Viral Gene Expression.
Recognition of hyperacetylated N-terminus of H2AZ by TbBDF2 from Trypanosoma brucei.
Proteomic characterization of the nucleolar linker histone H1 interaction network.
Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis.
Xie X, Moon PJ, Crossley SWM, Bischoff AJ, He D, Li G, Dao N, Gonzalez-Valero A, Reeves AG, McKenna JM, Elledge SK, Wells JA, Toste FD, Chang CJ
Nature 2024 Mar;627(8004):680-687
Nature 2024 Mar;627(8004):680-687
FXR1 stabilizes SNORD63 to regulate blood-tumor barrier permeability through SNORD63 mediated 2'-O-methylation of POU6F1.
Liang C, Zhai B, Wei D, Niu B, Ma J, Yao Y, Lin Y, Liu Y, Liu X, Wang P
International journal of biological macromolecules 2024 Apr;265(Pt 1):130642
International journal of biological macromolecules 2024 Apr;265(Pt 1):130642
U2AF2-SNORA68 promotes triple-negative breast cancer stemness through the translocation of RPL23 from nucleoplasm to nucleolus and c-Myc expression.
Zhang W, Song X, Jin Z, Zhang Y, Li S, Jin F, Zheng A
Breast cancer research : BCR 2024 Apr 9;26(1):60
Breast cancer research : BCR 2024 Apr 9;26(1):60
Elucidation of the mechanism of nuclear localization of Mexican tetra Neu4 via bipartite nuclear localization signal and less conserved regions.
Hyodo T, Honda A, Yamate S, Kubo Y, Komatsu M, Shiozaki K
Biochimie 2023 Sep;212:123-134
Biochimie 2023 Sep;212:123-134
Nascent ribosomal RNA act as surfactant that suppresses growth of fibrillar centers in nucleolus.
Yamamoto T, Yamazaki T, Ninomiya K, Hirose T
Communications biology 2023 Nov 7;6(1):1129
Communications biology 2023 Nov 7;6(1):1129
Nucleolus assembly impairment leads to two-cell transcriptional repression via NPM1-mediated PRC2 recruitment.
Li D, Cao R, Li Q, Yang Y, Tang A, Zhang J, Liu Q
Nature structural & molecular biology 2023 Jul;30(7):914-925
Nature structural & molecular biology 2023 Jul;30(7):914-925
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
Feng Y, Han Y, Hu A, Qu Y, Hu Y, Wu H, Wang X, He L
Acta pharmaceutica Sinica. B 2023 Feb;13(2):598-617
Acta pharmaceutica Sinica. B 2023 Feb;13(2):598-617
SNORD17-mediated KAT6B mRNA 2'-O-methylation regulates vasculogenic mimicry in glioblastoma cells.
Cui J, Liu X, Dong W, Liu Y, Ruan X, Zhang M, Wang P, Liu L, Xue Y
Cell biology and toxicology 2023 Dec;39(6):2841-2860
Cell biology and toxicology 2023 Dec;39(6):2841-2860
SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway.
Wu W, Chen X, Liu X, Bao HJ, Li QH, Xian JY, Lu BF, Zhao Y, Chen S
Molecular carcinogenesis 2023 Apr;62(4):413-426
Molecular carcinogenesis 2023 Apr;62(4):413-426
Small Nucleolar RNA and C/D Box 15B Regulate the TRIM25/P53 Complex to Promote the Development of Endometrial Cancer.
Wen JT, Chen X, Liu X, Xie BM, Chen JW, Qin HL, Zhao Y
Journal of oncology 2022;2022:7762708
Journal of oncology 2022;2022:7762708
RNA 2'-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response.
Li P, Liu Y, Song R, Zhao L, Yang J, Lu F, Cao X
Frontiers in immunology 2022;13:793582
Frontiers in immunology 2022;13:793582
Identification and mapping of post-transcriptional modifications on the HIV-1 antisense transcript Ast in human cells.
Estevez M, Li R, Paul B, Daneshvar K, Mullen AC, Romerio F, Addepalli B
RNA (New York, N.Y.) 2022 May;28(5):697-710
RNA (New York, N.Y.) 2022 May;28(5):697-710
C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2'-O-methylation of PARP1.
Lu B, Chen X, Liu X, Chen J, Qin H, Chen S, Zhao Y
Journal of translational medicine 2022 Dec 24;20(1):618
Journal of translational medicine 2022 Dec 24;20(1):618
METTL3 preferentially enhances non-m(6)A translation of epigenetic factors and promotes tumourigenesis.
Wei X, Huo Y, Pi J, Gao Y, Rao S, He M, Wei Q, Song P, Chen Y, Lu D, Song W, Liang J, Xu L, Wang H, Hong G, Guo Y, Si Y, Xu J, Wang X, Ma Y, Yu S, Zou D, Jin J, Wang F, Yu J
Nature cell biology 2022 Aug;24(8):1278-1290
Nature cell biology 2022 Aug;24(8):1278-1290
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Luo W, Li J, Li Z, Lin T, Zhang L, Yang W, Mai Y, Liu R, Chen M, Dai C, Yang H, Lu J, Li H, Guan G, Huang M, Liu P, Li Z
Cell death & disease 2021 Jul 26;12(8):738
Cell death & disease 2021 Jul 26;12(8):738
LARP7-Mediated U6 snRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice.
Wang X, Li ZT, Yan Y, Lin P, Tang W, Hasler D, Meduri R, Li Y, Hua MM, Qi HT, Lin DH, Shi HJ, Hui J, Li J, Li D, Yang JH, Lin J, Meister G, Fischer U, Liu MF
Molecular cell 2020 Mar 5;77(5):999-1013.e6
Molecular cell 2020 Mar 5;77(5):999-1013.e6
Dual regulation of p53 by the ribosome maturation factor SBDS.
Hao Q, Wang J, Chen Y, Wang S, Cao M, Lu H, Zhou X
Cell death & disease 2020 Mar 20;11(3):197
Cell death & disease 2020 Mar 20;11(3):197
Differential roles of two DDX17 isoforms in the formation of membraneless organelles.
Hirai Y, Domae E, Yoshikawa Y, Tomonaga K
Journal of biochemistry 2020 Jul 1;168(1):33-40
Journal of biochemistry 2020 Jul 1;168(1):33-40
Zika Virus Subverts Stress Granules To Promote and Restrict Viral Gene Expression.
Bonenfant G, Williams N, Netzband R, Schwarz MC, Evans MJ, Pager CT
Journal of virology 2019 Jun 15;93(12)
Journal of virology 2019 Jun 15;93(12)
Recognition of hyperacetylated N-terminus of H2AZ by TbBDF2 from Trypanosoma brucei.
Yang X, Wu X, Zhang J, Zhang X, Xu C, Liao S, Tu X
The Biochemical journal 2017 Nov 9;474(22):3817-3830
The Biochemical journal 2017 Nov 9;474(22):3817-3830
Proteomic characterization of the nucleolar linker histone H1 interaction network.
Szerlong HJ, Herman JA, Krause CM, DeLuca JG, Skoultchi A, Winger QA, Prenni JE, Hansen JC
Journal of molecular biology 2015 Jun 5;427(11):2056-71
Journal of molecular biology 2015 Jun 5;427(11):2056-71
Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis.
Liu X, Wang X, Du W, Chen L, Wang G, Cui Y, Liu Y, Dou Z, Wang H, Zhang P, Chang L, Yi L, Cai J, Jiang C
Oncotarget 2014 Nov 30;5(22):11681-94
Oncotarget 2014 Nov 30;5(22):11681-94
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The FBL antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FBL. This antibody recognizes human, mouse, rat antigen. The FBL antibody has been validated for the following applications: ELISA, WB analysis.
