BS6334

antibody from Bioworld Technology, Inc
Targeting: ATM ATA, ATC, ATD, ATDC, TEL1, TELO1
Provider product page for BS6334
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6334 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ATM (phospho S1981) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human ATM around the phosphorylation site of Serine 1981.
Description
The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy-termini that is not present in the PI 3- and PI 4-kinases. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiec-tases) in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ATM protein structure - BS6334 shown in red.