ATM

gene product
ATA, ATC, ATD, ATDC, TEL1, TELO1
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
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Antibodies

 

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Antibodypedia Validation Initiative

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  or   Clear
Enhanced validation
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Eligible for validation within AVI
1265 antibodies from 41 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
26 antibodies
antibodies-online
472 antibodies
Novus Biologicals
57 antibodies
Invitrogen Antibodies
22 antibodies
Rockland Immunochemicals, Inc.
7 antibodies
Bethyl Laboratories
4 antibodies
Abnova Corporation
21 antibodies
Boster Biological Technology
7 antibodies
OriGene
25 antibodies
NovoPro Bioscience Inc.
4 antibodies
R&D Systems
4 antibodies
Biorbyt
68 antibodies
Cell Signaling Technology, Inc
5 antibodies
Bioworld Technology, Inc
6 antibodies
Affinity Biosciences
8 antibodies
Abgent
9 antibodies
Acris Antibodies GmbH
26 antibodies
LifeSpan BioSciences, Inc.
173 antibodies