DCABH-1697

antibody from Creative Diagnostics

Targeting: ATM ATA, ATC, ATD, ATDC, TEL1, TELO1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

DCABH-1697

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-1697, RRID:AB_2475649

Product name

Rabbit Anti-ACTA2 monoclonal antibody, clone TZ13-75

Antibody type

Monoclonal

Description

All eukaryotic cells express Actin, which often constitutes as much as 50% of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one Actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of Actin are present in mammalian tissues and fall into three classes. Ï«-Actin expression is limited to various types of muscle, whereas ÉÇ-Actin and ÎÛ-Actin are the principle constituents of filaments in other tissues. Members of the small GTPase family regulate the organization of the Actin cytoskeleton. Rho controls the assembly of Actin stress fibers and focal adhesion. Rac regulates Actin filament accumulation at the plasma membrane. Cdc42 stimulates formation of filopodia.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

TZ13-75

Vial size

100 _l

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.