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Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [4]
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- Product number
- GTX70105 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX70105, RRID:AB_368163
- Product name
- ATM antibody [3E8]
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Mouse
Submitted references Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM-p53 cascade in colon cancer cell lines.
Recruitment of ataxia-telangiectasia mutated to the p21(waf1) promoter by ZBP-89 plays a role in mucosal protection.
Involvement of the ATR- and ATM-dependent checkpoint responses in cell cycle arrest evoked by pierisin-1.
Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage.
ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation.
Fini L, Hotchkiss E, Fogliano V, Graziani G, Romano M, De Vol EB, Qin H, Selgrad M, Boland CR, Ricciardiello L
Carcinogenesis 2008 Jan;29(1):139-46
Carcinogenesis 2008 Jan;29(1):139-46
Recruitment of ataxia-telangiectasia mutated to the p21(waf1) promoter by ZBP-89 plays a role in mucosal protection.
Bai L, Kao JY, Law DJ, Merchant JL
Gastroenterology 2006 Sep;131(3):841-52
Gastroenterology 2006 Sep;131(3):841-52
Involvement of the ATR- and ATM-dependent checkpoint responses in cell cycle arrest evoked by pierisin-1.
Shiotani B, Kobayashi M, Watanabe M, Yamamoto K, Sugimura T, Wakabayashi K
Molecular cancer research : MCR 2006 Feb;4(2):125-33
Molecular cancer research : MCR 2006 Feb;4(2):125-33
Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage.
Post S, Weng YC, Cimprich K, Chen LB, Xu Y, Lee EY
Proceedings of the National Academy of Sciences of the United States of America 2001 Nov 6;98(23):13102-7
Proceedings of the National Academy of Sciences of the United States of America 2001 Nov 6;98(23):13102-7
ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation.
Chen MJ, Lin YT, Lieberman HB, Chen G, Lee EY
The Journal of biological chemistry 2001 May 11;276(19):16580-6
The Journal of biological chemistry 2001 May 11;276(19):16580-6
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ug of whole cell lysate) A: 293T B: A431 5% SDS PAGE GTX70105 diluted at 1:1000
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Human Kidney (formalin-fixed, paraffin-embedded) stained with ATM antibody at 5 ?g/ml followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded U373 xenograft, using ATM(GTX70105) antibody at 1:200 dilution.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded RT2 xenograft, using ATM(GTX70105) antibody at 1:200 dilution.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded C2C12 xenograft, using ATM(GTX70105) antibody at 1:200 dilution.
