Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- GTX77613 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX77613, RRID:AB_377546
- Product name
- ATM antibody [2C1] (supernatant)
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Mouse
Submitted references Regulation of CHK2 by DNA-dependent protein kinase.
ATP activates ataxia-telangiectasia mutated (ATM) in vitro. Importance of autophosphorylation.
Sensing of intermediates in V(D)J recombination by ATM.
Elevated DNA double strand breaks and apoptosis in the CNS of scid mutant mice.
Meiotic telomere distribution and Sertoli cell nuclear architecture are altered in Atm- and Atm-p53-deficient mice.
Li J, Stern DF
The Journal of biological chemistry 2005 Mar 25;280(12):12041-50
The Journal of biological chemistry 2005 Mar 25;280(12):12041-50
ATP activates ataxia-telangiectasia mutated (ATM) in vitro. Importance of autophosphorylation.
Kozlov S, Gueven N, Keating K, Ramsay J, Lavin MF
The Journal of biological chemistry 2003 Mar 14;278(11):9309-17
The Journal of biological chemistry 2003 Mar 14;278(11):9309-17
Sensing of intermediates in V(D)J recombination by ATM.
Perkins EJ, Nair A, Cowley DO, Van Dyke T, Chang Y, Ramsden DA
Genes & development 2002 Jan 15;16(2):159-64
Genes & development 2002 Jan 15;16(2):159-64
Elevated DNA double strand breaks and apoptosis in the CNS of scid mutant mice.
Vemuri MC, Schiller E, Naegele JR
Cell death and differentiation 2001 Mar;8(3):245-55
Cell death and differentiation 2001 Mar;8(3):245-55
Meiotic telomere distribution and Sertoli cell nuclear architecture are altered in Atm- and Atm-p53-deficient mice.
Scherthan H, Jerratsch M, Dhar S, Wang YA, Goff SP, Pandita TK
Molecular and cellular biology 2000 Oct;20(20):7773-83
Molecular and cellular biology 2000 Oct;20(20):7773-83
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa D: HepG2 5% SDS PAGE GTX77613 diluted at 1:100
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ATM(GTX77613) antibody at 1:100 dilution.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded Hepatoma, using ATM(GTX77613) antibody at 1:50 dilution.