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- Antigen structure
- References [5]
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- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- GTX132146 - Provider product page
- Provider
- GeneTex
- Product name
- ATM (phospho Ser1981) antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse
- Host
- Rabbit
Submitted references Radiation-induced DNA damage response and resistance in colorectal cancer stem-like cells.
Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells.
Reactive Oxygen Species (ROS)-Activated ATM-Dependent Phosphorylation of Cytoplasmic Substrates Identified by Large-Scale Phosphoproteomics Screen.
A synthetic lethal screen reveals enhanced sensitivity to ATR inhibitor treatment in mantle cell lymphoma with ATM loss-of-function.
N-Hydroxycinnamide derivatives of osthole presenting genotoxicity and cytotoxicity against human colon adenocarcinoma cells in vitro and in vivo.
Anuja K, Chowdhury AR, Saha A, Roy S, Rath AK, Kar M, Banerjee B
International journal of radiation biology 2019 Feb 12;:1-13
International journal of radiation biology 2019 Feb 12;:1-13
Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells.
Benedict B, van Harn T, Dekker M, Hermsen S, Kucukosmanoglu A, Pieters W, Delzenne-Goette E, Dorsman JC, Petermann E, Foijer F, Te Riele H
eLife 2018 Oct 16;7
eLife 2018 Oct 16;7
Reactive Oxygen Species (ROS)-Activated ATM-Dependent Phosphorylation of Cytoplasmic Substrates Identified by Large-Scale Phosphoproteomics Screen.
Kozlov SV, Waardenberg AJ, Engholm-Keller K, Arthur JW, Graham ME, Lavin M
Molecular & cellular proteomics : MCP 2016 Mar;15(3):1032-47
Molecular & cellular proteomics : MCP 2016 Mar;15(3):1032-47
A synthetic lethal screen reveals enhanced sensitivity to ATR inhibitor treatment in mantle cell lymphoma with ATM loss-of-function.
Menezes DL, Holt J, Tang Y, Feng J, Barsanti P, Pan Y, Ghoddusi M, Zhang W, Thomas G, Holash J, Lees E, Taricani L
Molecular cancer research : MCR 2015 Jan;13(1):120-9
Molecular cancer research : MCR 2015 Jan;13(1):120-9
N-Hydroxycinnamide derivatives of osthole presenting genotoxicity and cytotoxicity against human colon adenocarcinoma cells in vitro and in vivo.
Liu LY, Huang WJ, Lin RJ, Lin SY, Liang YC
Chemical research in toxicology 2013 Nov 18;26(11):1683-91
Chemical research in toxicology 2013 Nov 18;26(11):1683-91
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Untreated (¡V) and treated (+) HCT116 whole cell extracts (30 £gg) were separated by 5% SDS-PAGE, and the membrane was blotted with ATM (phospho Ser1981) antibody (GTX132146) diluted at 1:1000.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Untreated (¡V) and treated (+) 293T whole cell extracts (30 ?g) were separated by 5% SDS-PAGE, and the membrane was blotted with ATM (phospho Ser1981) antibody (GTX132146) diluted at 1:1000.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- ATM (phospho Ser1981) antibody detects ATM (phospho Ser1981) protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human cervical carcinoma.ATM (phospho Ser1981) stained by ATM (phospho Ser1981) antibody (GTX132146) diluted at 1:500.
