Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362099 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN362099, RRID:AB_10954595
- Product name
- anti-Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer1981 (E-G-S (p) -Q-S) derived from Human ATM. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- pSer1981
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Identification of signaling pathways mediating cell cycle arrest and apoptosis induced by Porphyromonas gingivalis in human trophoblasts.
Mutant telomerase RNAs induce DNA damage and apoptosis via the TRF2-ATM pathway in telomerase-overexpressing primary fibroblasts.
ATM localization and gene expression in the adult mouse eye.
Expression status of ataxia-telangiectasia-mutated gene correlated with prognosis in advanced gastric cancer.
Involvement of human MOF in ATM function.
Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint.
The ATM-related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment.
Workshop on The Epidemiology of the ATM Gene: Impact on Breast Cancer Risk and Treatment, Present Status and Future Focus, Lillehammer, Norway, 29 June 2002.
Inaba H, Kuboniwa M, Sugita H, Lamont RJ, Amano A
Infection and immunity 2012 Aug;80(8):2847-57
Infection and immunity 2012 Aug;80(8):2847-57
Mutant telomerase RNAs induce DNA damage and apoptosis via the TRF2-ATM pathway in telomerase-overexpressing primary fibroblasts.
Mahalingam D, Tay LL, Tan WH, Chai JH, Wang X
The FEBS journal 2011 Oct;278(19):3724-38
The FEBS journal 2011 Oct;278(19):3724-38
ATM localization and gene expression in the adult mouse eye.
Leemput J, Masson C, Bigot K, Errachid A, Dansault A, Provost A, Gadin S, Aoufouchi S, Menasche M, Abitbol M
Molecular vision 2009;15:393-416
Molecular vision 2009;15:393-416
Expression status of ataxia-telangiectasia-mutated gene correlated with prognosis in advanced gastric cancer.
Kang B, Guo RF, Tan XH, Zhao M, Tang ZB, Lu YY
Mutation research 2008 Feb 1;638(1-2):17-25
Mutation research 2008 Feb 1;638(1-2):17-25
Involvement of human MOF in ATM function.
Gupta A, Sharma GG, Young CS, Agarwal M, Smith ER, Paull TT, Lucchesi JC, Khanna KK, Ludwig T, Pandita TK
Molecular and cellular biology 2005 Jun;25(12):5292-305
Molecular and cellular biology 2005 Jun;25(12):5292-305
Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint.
Silverman J, Takai H, Buonomo SB, Eisenhaber F, de Lange T
Genes & development 2004 Sep 1;18(17):2108-19
Genes & development 2004 Sep 1;18(17):2108-19
The ATM-related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment.
Nakada D, Shimomura T, Matsumoto K, Sugimoto K
Nucleic acids research 2003 Mar 15;31(6):1715-24
Nucleic acids research 2003 Mar 15;31(6):1715-24
Workshop on The Epidemiology of the ATM Gene: Impact on Breast Cancer Risk and Treatment, Present Status and Future Focus, Lillehammer, Norway, 29 June 2002.
Bernstein JL, Seminara D, Børresen-Dale AL
Breast cancer research : BCR 2002;4(6):249-52
Breast cancer research : BCR 2002;4(6):249-52
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