PAB12190

antibody from Abnova Corporation

Targeting: ABL1 ABL, c-ABL, JTK7, p150

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB12190

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB12190, RRID:AB_10548288

Product name

ABL1/ABL2 (phospho Y393/Y429) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y393/Y429 of human ABL1/ABL2.

Reactivity

Human

Host

Rabbit

Antigen sequence

DTYpTA


Vial size

100 µg

Concentration

1 mg/mL

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Autoinhibition of c-Abl.

Pluk H, Dorey K, Superti-Furga G
Cell 2002 Jan 25;108(2):247-59

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c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines.

Brasher BB, Van Etten RA
The Journal of biological chemistry 2000 Nov 10;275(45):35631-7

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JAK-STAT signaling activated by Abl oncogenes.

Danial NN, Rothman P
Oncogene 2000 May 15;19(21):2523-31

Immunocytochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunofluorescence staining of methanol-fixed HeLa cells using ABL1/ABL2 (phospho Y393/429) polyclonal antibody (Cat # PAB12190, red).

Validation comment

Immunofluorescence

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ABL1/ABL2 (phospho Y393/429) polyclonal antibody (Cat # PAB12190).

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)