Tissue expression
Cell line expression
Protein structure

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL, c-ABL, JTK7, p150 
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [provided by RefSeq, Aug 2014]
More gene data

All Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
2475 antibodies from 44 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
63 antibodies
GeneTex
22 antibodies
antibodies-online
771 antibodies
Biorbyt
373 antibodies
Abnova Corporation
22 antibodies
Novus Biologicals
11 antibodies
Affinity Biosciences
11 antibodies
OriGene
43 antibodies
Cusabio Biotech Co., Ltd
22 antibodies
Abgent
14 antibodies
Acris Antibodies GmbH
50 antibodies
NovoPro Bioscience Inc.
12 antibodies
Boster Biological Technology
10 antibodies
Aviva Systems Biology
22 antibodies
NSJ Bioreagents
6 antibodies
Bethyl Laboratories
3 antibodies
Atlas Antibodies
3 antibodies
Signalway Antibody LLC
2 antibodies
St John's Laboratory
25 antibodies
Bioworld Technology, Inc
11 antibodies
Cell Signaling Technology, Inc
7 antibodies
Arigo
6 antibodies
R&D Systems
1 antibody
ProSci
8 antibodies
FabGennix
3 antibodies
Abbkine Scientific Co.Ltd.
12 antibodies
Creative Diagnostics
12 antibodies
RabMAbs
4 antibodies
MyBioSource
27 antibodies
Creative Biolabs
48 antibodies
MilliporeSigma / Merck KGaA
12 antibodies
Abbexa
39 antibodies
GenWay
10 antibodies
EMD Millipore
7 antibodies
United States Biological
298 antibodies
Spring Bioscience
4 antibodies
Leading Biology
6 antibodies
Abiocode, Inc.
1 antibody
Proteintech Group
1 antibody
RayBiotech, Inc.
1 antibody
Abbiotec
1 antibody
BioLegend (formerly Covance Antibody Products)
1 antibody