Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN2839559 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr134) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pTyr134
- Antibody clone number
- RB7343
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references MEK-dependent negative feedback underlies BCR-ABL-mediated oncogene addiction.
Interpretation of submicroscopic deletions of the BCR or ABL gene should not depend on extra signal-FISH: problems in interpretation of submicroscopic deletion of the BCR or ABL gene with extra signal-FISH.
Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation.
Derivative chromosome 9 deletions are a significant feature of childhood Philadelphia chromosome positive acute lymphoblastic leukaemia.
Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides.
Insights into selective activation of p53 DNA binding by c-Abl.
Asmussen J, Lasater EA, Tajon C, Oses-Prieto J, Jun YW, Taylor BS, Burlingame A, Craik CS, Shah NP
Cancer discovery 2014 Feb;4(2):200-15
Cancer discovery 2014 Feb;4(2):200-15
Interpretation of submicroscopic deletions of the BCR or ABL gene should not depend on extra signal-FISH: problems in interpretation of submicroscopic deletion of the BCR or ABL gene with extra signal-FISH.
Kim YR, Cho HI, Yoon SS, Park S, Kim BK, Lee YK, Chun H, Kim HC, Lee DS
Genes, chromosomes & cancer 2005 May;43(1):37-44
Genes, chromosomes & cancer 2005 May;43(1):37-44
Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation.
Barnes K, McIntosh E, Whetton AD, Daley GQ, Bentley J, Baldwin SA
Oncogene 2005 May 5;24(20):3257-67
Oncogene 2005 May 5;24(20):3257-67
Derivative chromosome 9 deletions are a significant feature of childhood Philadelphia chromosome positive acute lymphoblastic leukaemia.
Robinson HM, Martineau M, Harris RL, Barber KE, Jalali GR, Moorman AV, Strefford JC, Broadfield ZJ, Cheung KL, Harrison CJ
Leukemia 2005 Apr;19(4):564-71
Leukemia 2005 Apr;19(4):564-71
Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides.
Aichberger KJ, Mayerhofer M, Krauth MT, Skvara H, Florian S, Sonneck K, Akgul C, Derdak S, Pickl WF, Wacheck V, Selzer E, Monia BP, Moriggl R, Valent P, Sillaber C
Blood 2005 Apr 15;105(8):3303-11
Blood 2005 Apr 15;105(8):3303-11
Insights into selective activation of p53 DNA binding by c-Abl.
Wei G, Li AG, Liu X
The Journal of biological chemistry 2005 Apr 1;280(13):12271-8
The Journal of biological chemistry 2005 Apr 1;280(13):12271-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC