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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN358068 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr245) antibody
- Antibody type
- Polyclonal
- Description
- Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pTyr245
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia.
Bcr-Abl regulates protein kinase Ciota (PKCiota) transcription via an Elk1 site in the PKCiota promoter.
Abl: the prototype of oncogenic fusion proteins.
Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.
Fluorescent in situ hybridization analysis of Philadelphia chromosome-negative chronic myeloid leukemia with the bcr/abl fusion gene.
Graux C, Cools J, Melotte C, Quentmeier H, Ferrando A, Levine R, Vermeesch JR, Stul M, Dutta B, Boeckx N, Bosly A, Heimann P, Uyttebroeck A, Mentens N, Somers R, MacLeod RA, Drexler HG, Look AT, Gilliland DG, Michaux L, Vandenberghe P, Wlodarska I, Marynen P, Hagemeijer A
Nature genetics 2004 Oct;36(10):1084-9
Nature genetics 2004 Oct;36(10):1084-9
Bcr-Abl regulates protein kinase Ciota (PKCiota) transcription via an Elk1 site in the PKCiota promoter.
Gustafson WC, Ray S, Jamieson L, Thompson EA, Brasier AR, Fields AP
The Journal of biological chemistry 2004 Mar 5;279(10):9400-8
The Journal of biological chemistry 2004 Mar 5;279(10):9400-8
Abl: the prototype of oncogenic fusion proteins.
Saglio G, Cilloni D
Cellular and molecular life sciences : CMLS 2004 Dec;61(23):2897-911
Cellular and molecular life sciences : CMLS 2004 Dec;61(23):2897-911
Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.
Deming PB, Schafer ZT, Tashker JS, Potts MB, Deshmukh M, Kornbluth S
Molecular and cellular biology 2004 Dec;24(23):10289-99
Molecular and cellular biology 2004 Dec;24(23):10289-99
Fluorescent in situ hybridization analysis of Philadelphia chromosome-negative chronic myeloid leukemia with the bcr/abl fusion gene.
Monma F, Nishii K, Yamamori S, Hosokai N, Nakazaki T, Lorenzo F 5th, Usui E, Sakakura M, Miyashita H, Fujieda A, Ohishi K, Katayama N, Shiku H
International journal of hematology 2004 Aug;80(2):155-8
International journal of hematology 2004 Aug;80(2):155-8
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