ABIN965708

antibody from antibodies-online

Targeting: ABL1 ABL, c-ABL, JTK7, p150

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN965708

Provider

antibodies-online

Product name

anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr412) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human cAbl around the phosphorylation site of tyrosine 412 (D-T-YP-T-A).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse

Host

Rabbit

Epitope

pTyr412

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

Inactivation of NF-kappaB-dependent cell survival, a novel mechanism for the proapoptotic function of c-Abl.

Kawai H, Nie L, Yuan ZM
Molecular and cellular biology 2002 Sep;22(17):6079-88

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c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage.

Yoshida K, Komatsu K, Wang HG, Kufe D
Molecular and cellular biology 2002 May;22(10):3292-300

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c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination.

Sionov RV, Coen S, Goldberg Z, Berger M, Bercovich B, Ben-Neriah Y, Ciechanover A, Haupt Y
Molecular and cellular biology 2001 Sep;21(17):5869-78

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Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage.

Kharbanda S, Pandey P, Yamauchi T, Kumar S, Kaneki M, Kumar V, Bharti A, Yuan ZM, Ghanem L, Rana A, Weichselbaum R, Johnson G, Kufe D
Molecular and cellular biology 2000 Jul;20(14):4979-89