Tissue expression
Cell line expression
Protein structure
NKAP
NFKB activating proteinFLJ22626
This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010]
Top validated antibodies |
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antibodies-online | ![]() |
4 references | Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Abnova Corporation | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
Polyclonal |
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