Antibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN394040 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Centromere Protein A (CENPA) (AA 1-115) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-115
- Isotype
- IgG
- Antibody clone number
- 1D4-1A3
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses.
Molecular and evolutionary characteristics of the fraction of human alpha satellite DNA associated with CENP-A at the centromeres of chromosomes 1, 5, 19, and 21.
Dual recognition of CENP-A nucleosomes is required for centromere assembly.
HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres.
Building centromeres: home sweet home or a nomadic existence?
Maehara K, Takahashi K, Saitoh S
Molecular and cellular biology 2010 May;30(9):2090-104
Molecular and cellular biology 2010 May;30(9):2090-104
Molecular and evolutionary characteristics of the fraction of human alpha satellite DNA associated with CENP-A at the centromeres of chromosomes 1, 5, 19, and 21.
Pironon N, Puechberty J, Roizès G
BMC genomics 2010 Mar 23;11:195
BMC genomics 2010 Mar 23;11:195
Dual recognition of CENP-A nucleosomes is required for centromere assembly.
Carroll CW, Milks KJ, Straight AF
The Journal of cell biology 2010 Jun 28;189(7):1143-55
The Journal of cell biology 2010 Jun 28;189(7):1143-55
HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres.
Shuaib M, Ouararhni K, Dimitrov S, Hamiche A
Proceedings of the National Academy of Sciences of the United States of America 2010 Jan 26;107(4):1349-54
Proceedings of the National Academy of Sciences of the United States of America 2010 Jan 26;107(4):1349-54
Building centromeres: home sweet home or a nomadic existence?
Buscaino A, Allshire R, Pidoux A
Current opinion in genetics & development 2010 Apr;20(2):118-26
Current opinion in genetics & development 2010 Apr;20(2):118-26
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