Tissue expression
Cell line expression
Protein structure
CENPA
Centromere protein ACenH3, CENP-A
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015]
Top validated antibodies |
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GeneTex | GTX13939 | 12 references | Monoclonal |
WB
ICC
IHC
BN |
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Invitrogen Antibodies | MA1-20832 | 1 references | Monoclonal |
WB
ICC
IHC
BN |
|
Enzo Life Sciences | ADI-KAM-CC006-E | 1 references | Monoclonal |
WB
ICC
IHC
|
|
Cell Signaling Technology, Inc | 2187 | 1 references | Polyclonal |
WB
ICC
IP
|
|
Abnova Corporation | PAB18324 | 3 references | Polyclonal |
ICC
IHC |
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