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Learn20700-1-AP
antibody from Proteintech Group
Targeting: RUNX2
AML3, CBFA1, CCD, CCD1, PEBP2A1, PEBP2aA1
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- Antibody Data
- Antigen structure
- References [362]
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- Product number
- 20700-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20700-1-AP, RRID:AB_2722783
- Product name
- RUNX2 antibody
- Antibody type
- Polyclonal
- Description
- RUNX2 antibody (Cat. #20700-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references OsteoNet: A deep learning framework linking cellular morphology to molecular markers for quantifying osteogenic differentiation.
Spatholobus suberectus Stem-Derived Extracellular Vesicle-Like Particles Attenuate Glucocorticoid-Induced Osteoporosis via NRF2/HO-1 Signaling.
Magnesium-doped bioactive glass enhances bone regeneration by reversing replicative senescence of human dental pulp stem cells in bone defect therapy.
Quercetin attenuates tendon stem/progenitor cell senescence and promotes aged tendon repair via AKT/NF-κB/NLRP3-mediated mitophagy activation.
Farnesol Targets the GSTP1/MAPK Axis to Inhibit Trauma-Induced Tendon Heterotopic Ossification.
Isoliquiritigenin restores bone homeostasis in osteoporotic rats by enhancing BMSCs osteogenesis via ERK1/2-mTOR-HIF-1α-glycolytic axis and suppressing inflammation.
Small molecule HCY-NBD stabilizes GSTM2 via cys174 sulfenylation to attenuate high glucose induced endothelial cell senescence and calcification.
Osteoblast-derived osteomodulin restrains osteoclastogenesis via ITGB8/RRM2-mediated reduction of mitochondrial respiration and mitochondrial ATP production.
Magnesium ion implantation enhances the osseointegration and vascularization of 3D-Printed CoCrMo alloy scaffolds for load-bearing orthopedic applications.
SLIT3/ROBO1 axis contributes to angiogenic-osteogenic coupling in endothelial progenitor cells and peripheral blood mesenchymal stem cells.
Identification of hub targets involved in carotid atherosclerosis through bioinformatics and machine learning approaches.
Microfluidic Encapsulation of Genetically Engineered Bone-marrow-derived Mesenchymal Stem Cells for Bone Defect Healing.
Kaempferide alleviates glucocorticoid-induced osteoporosis by targeting ferroptosis through the GSK3β/Nrf-2/GPX4 pathway.
A multimodal ROS logic-gated therapeutic platform disrupts the vicious cycle of senescence to promote aged bone defect repair.
A composite sustained-release system with immunomodulatory and synergistic osteogenic differentiation effects for repairing inflammatory alveolar bone defects.
From Cells to Animals: Connexin43 Suppression Enhances Autophagic Flux to Restore Odontogenesis in Inflamed Dental Pulp.
Calpeptin promotes osteogenesis through the Dlx3-RUNX2 pathway: in vitro and in vivo evidence for a dual-action osteoporosis therapy.
Yigu Decoction polysaccharides mediate gut microbiota and metabolites to promote bone formation-related protein expression and improve osteoporosis.
Suppression of distal-less homeobox 3 increased alveolar bone mass in mouse tooth socket by targeting thrombospondin 1.
Melatonin promotes osteogenic differentiation of BMSCs by regulating circZFAND1/miR-433-3p/DKK1 pathway through melatonin receptor-dependent m6A modification of circZFAND1.
An Injectable, Osteoconductive Gelatin-Enabled GelMA/HAp Hydrogel Scaffold for Minimally Invasive Bone Tissue Engineering.
Calcium carbonate supplementation exacerbated gut microenvironment disruption in senile osteoporosis mice.
Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection.
Development of a Gelatin-Based Composite Hydrogel Powder with Kaolin and Sr-Doped Hydroxyapatite for Dual Hemostatic and Osteogenic Potential.
Pilose antler peptide enhances diabetic fracture healing by modulating the CREB-Smad2/3-Runx2 signaling axis.
FBXO5 alleviates apical periodontitis by facilitating TP53 protein degradation.
Biomineralization-inspired scaffolds using citrate-based polymers to stabilize amorphous calcium phosphate promote osteogenesis and angiogenesis for bone defect repair.
Autophagy-induced osteoblast-derived exosomes maintain bone formation and prevent osteoporosis by remodeling gut microbiota-metabolism.
Bilayer Hydrogel Scaffold with Directional Micro-Channels and Mechanical Gradient to Promote Osteochondral Repair.
WTAP Contributes to Periodontitis Pathogenesis by Promoting PDLSC Senescence and Impairing Osteogenic Differentiation via m6A-Dependent Regulation of TP53BP1.
A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation.
Transgenic high expression of EphB4 in canine periodontal ligament stem cells modulates osteogenic differentiation and migration in cPDLSCs.
Kaempferol Alleviates Glucocorticoid-Induced Osteonecrosis of the Femoral Head by Modulating Macrophage M1/M2 Polarization Through RhoA/ROCK-Mediated Mitophagy Activation.
MECP2 Insufficiency Attenuates RUNX2-Dependent Osteoblast Differentiation via miR-126-3p/DKK1-Mediated Canonical Wnt Signaling Inhibition in Rett Syndrome.
Psoralen Promotes Direct Chemical Reprogramming of Mouse Embryonic Fibroblasts into Osteoblast-like Cells.
Supramolecular delivery of senolytics enables targeted anti-senescence therapy and accelerated fracture healing.
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
BMP2@PDA-LDH functionalized coating on ZK60 magnesium alloy: Enhanced corrosion resistance and promoted bone defect regeneration.
Bioinspired scaffold recapitulating chondrogenic ontogeny and microenvironment for functional cartilage regeneration.
3D-printed titanium scaffolds coated with a multifunctional photothermal-responsive hydrogel promote osteoporotic bone defect repair.
The multilayer coatings on polylactic acid implants spatiotemporally regulates the microenvironment to enhance antibacterial and osseointegration capacity.
A dual-functional Janus nanofibrous membrane as an immunomodulatory barrier for periodontitis regeneration under diabetic conditions.
Tannic acid-assisted mechanical training transforms natural hydrogels into robust and bioactive membranes for guided bone regeneration.
Graphene oxide coating on two-dimensional glass substrates and three-dimensional zirconia scaffolds for bone tissue regeneration.
Ultrasound-activated piezoelectric Silk-PVDF hydrogel reprograms the osteoimmune microenvironment via NRF2 signaling for accelerated bone regeneration.
Polyhedral oligomeric silsesquioxane-functionalized carboxymethyl chitin microspheres via irradiation-induced grafting for hemostasis and tissue repair in post-extraction sockets.
Dual-release 3D-printed porous Ti-6Al-4V implant with drug-eluting photothermal micro-nanotopographies: combating osteosarcoma recurrence, infections, and enhancing osteogenesis.
Identification and Screening of Lactate-Related Genes as Molecular Markers for Early Diagnosis of Steroid-Induced Osteonecrosis of the Femoral Head.
UHRF1-mediated DNA 5-mC modification drives super-enhancer redistribution and impedes osteogenesis via TGM2-regulated autophagic flux in senile osteoporosis.
Synergistic Antibacterial and Osteogenic Activities of Cu/Sr-Empowered 13-93 Bioglass in PMMA Composites for Sequential Promotion of Infectious Osseointegration.
Vericiguat improves CKD-related vascular calcification through the NO/cGMP/PKG pathway.
Dual improvement effects of ω-3 on bone loss and liver injury in rats with liver-bone axis damage.
Biphasic Scaffolds Functionalized with Piezoelectric Nanozymes for Osteochondral Defect Regeneration.
Functionalized Periosteum-Derived Microsphere-Hydrogel with Sequential Release of E7 Short Peptide/miR217 for Large Bone Defect Repairing.
Core transcriptional regulatory circuitry molecule ZNF217 promotes AML cell proliferation by up-regulating MYB.
Imbalance of Bone Homeostasis Caused by Nrf2 Deficiency Leads to Bone Loss in OVX Rats.
Effects and mechanisms of engineered exosomes pretreated with Scutellaria baicalensis Georgi on osteoporosis.
Salidroside Improves Periodontitis by Mitigating Inflammatory Reactions and Enhancing Osteogenic Differentiation of Human Periodontal Ligament Stem Cells.
Exosomes derived from Panax notoginseng promote osteogenic differentiation of rBMSCs via the PI3K/AKT signaling pathway.
Single-cell RNA-seq reveals a repair pattern in cystic lesions in steroid induced osteonecrosis of the femoral head.
Scorpion-Centipede extracts mitigate ovariectomy-induced osteoporosis in mice through facilitating Cx3cr1 expression.
Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/β-catenin signaling pathway.
Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.
Zirconia/dental pulp stem cell composite scaffolds repair osteogenic defect via regulating macrophages.
Shockwave-driven activation of endoplasmic reticulum stress in osteoblasts to enhance bone formation under osteoporotic conditions.
A pH-sensitive CuHP composite hydrogel featuring antibacterial, antioxidant and osteogenic properties for treating diabetic periodontitis.
Spatiotemporal regulation of the bone immune microenvironment via a 'Zn(2+)-quercetin' hierarchical delivery system for bone regeneration.
Osmotic stress inhibits osteoblast differentiation and mineralization by suppressing TRPV4-mediated calcium influx.
METTL14 promotes TBK1 mRNA stability through IGF2BP3-recognized m6A modification and enhances mitophagy in BMSCs.
Zingerone treats postmenopausal osteoporosis via increased ferroptosis sensitivity by p53-mediated regulation of SAT1 and GPX4 expression.
Transcription factor RUNX2 participates in astrocyte-mediated neuropathic pain via transcriptional activation of Ccl2.
4-Octyl Itaconate Attenuates Postmenopausal Osteoporosis by Inhibiting Ferroptosis and Enhancing Osteogenesis via the Nrf2 Pathway.
Dual stimulus-responsive dECM cryogel sequentially regulate bone microenvironment for one-step surgical therapy of chronic osteomyelitis.
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
TGF-β1/IL-11 positive loop between renal tubular epithelial cell and fibroblast promotes the ectopic calcification of renal interstitial fibroblasts in rats.
POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?
PIEZO1-GPX4 Axis Mediates Mechanical Stress-Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation.
Rabbits as preclinical animal models of cam morphology: proof of concept.
Genotype and phenotype correlation analysis in 27 families with multiple osteochondroma and validation by ATDC5 chondrocyte models.
Pak4-mediated crosstalk between necroptotic macrophages and tendon stem/progenitor cells contributes to traumatic heterotopic ossification formation.
M2-exo promote orthodontic bone remodeling via the MeCP2-TCF20-HDAC1 axis.
The impact of catalpol on osteogenic differentiation of the jaw bone marrow mesenchymal stem cells on the basis of network pharmacology, molecular docking and experimental validation.
Orally administered degradable nanoarmor-assisted probiotics for remodeling the gut microenvironment and treating osteoporosis.
H3K18 lactylation-hexokinase 2 positive feedback loop promotes osteogenesis of ASPCs in facial infiltrating lipomatosis.
Targeting SIRT3 to regulate mitophagy-dependent ferroptosis for preventing glucocorticoid-induced osteoporosis.
Nano-assisted dynamically assembled hydrogels with strong tissue adhesion and proactive immunomodulation for bone defect repair.
Autophagic damage in senescent bone marrow mesenchymal stromal cells: Impact on Piezo1 expression during osteoporosis progression.
Timosaponin B- II Enhances Osteogenic Differentiation of Human Periodontal Ligament Stem Cells via PI3K/AKT/GSK3β Signaling Pathway.
Moderate-intensity exercise attenuates bone loss in hyperuricemic nephropathic mice.
Virulence-Selective Trap-Capture-Kill Antibacterial Nanostructures With Immune-Metabolic Regulation for Treating Implant-Associated Infections.
Histone H3K18 lactylation-dependent epigenetic activation of RUNX2 orchestrates PI3K/AKT oncogenic signaling in laryngeal squamous cell carcinoma.
Kaempferol ameliorates BMSCs senescence in postmenopausal osteoporosis by targeting Sp1 to activate FUNDC1-mediated mitophagy.
Farnesyltransferase inhibitors decrease matrix-vesicle-mediated mineralization in SaOS-2 cells.
Modulation of Osteogenic Differentiation by CYBB in Osteoporotic Models.
Cranial repair-promoting effect of oxidised sodium alginate/amino gelatine injectable hydrogel loaded with deer antler blood peptides.
YTHDF3 regulates IL32 mRNA stability to promote osteogenic differentiation of bone mesenchymal stem cells in ankylosing spondylitis.
An Asymmetric Zn Membrane with Degradability, Antimicrobial, and Bone Immunomodulation for Guided Bone Regeneration.
SEC24D depletion induces osteogenic differentiation deficiency by inactivating the ATF6/TGF-β/Runx2 regulatory loop.
Accelerated differentiation of photothermal effect-induced mesenchymal stem cells regulated by activating HSP90-autophagy boosts wound repair.
METTL3 promotes osteogenesis by regulating N6-methyladenosine-dependent primary processing of hsa-miR-4526.
The surface protein Gbp of Fusobacterium nucleatum inhibits osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2.
Transcription factor SMAD5 upregulates ALG5 to alleviate osteoporosis development by inducing osteogenic differentiation.
Methacrylated silk fibroin based composite hydrogel with ROS-scavenging and osteogenic ability to orchestrate diabetic bone regeneration.
5,7-Dihydroxy-4-Methylcoumarin enhances osteogenesis and ameliorates osteoporosis via the AKT1 pathway.
Ginsenoside Rg1 regulating inflammatory response and bone-remodeling through Keap1/Nrf2 signaling pathway in rats with periodontitis.
Mechanistic Insights into Salvigenin for Glucocorticoid-Induced Femoral Head Osteonecrosis: A Network Pharmacology and Experimental Study.
METTL3-mediated m6A modification of circSTAT6 modulates miR-188-3p/Beclin1 axis to promote osteogenic differentiation of mesenchymal stem cells.
miR-138-5p inhibits healing of femoral fracture osteogenesis in rats by modulating osteoblast differentiation via SIRT1/FOXO1 axis.
Static Topographical Cue Combined with Dynamic Fluid Stimulation Enhances the Macrophage Extracellular Vesicle Yield and Therapeutic Potential for Bone Defects.
GIT2 negatively regulates the NF-κB pathway directly or indirectly by regulating TRAF3 expression to promote osteogenic differentiation of BMSCs.
The effects of FOXC2-gene-manipulated human periodontal ligament stem cells on bone regeneration of craniofacial bone defect.
CBD-conjugated BMP-inhibiting exosomes on collagen scaffold dual-target Achilles tendon repair: Synergistic regeneration and heterotopic ossification prevention.
A novel strategy for bone defect repair: Stromal cell-derived factor 1α sustained-release acellular fish scale scaffolds combined with injection of bone marrow mesenchymal stem cells promote bone regeneration.
Harnessing engineered exosomes as METTL3 carriers: Enhancing osteogenesis and suppressing lipogenesis in bone marrow mesenchymal stem cells for postmenopausal osteoporosis treatment.
Targeted Delivery of α-ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes.
Icariin-loaded composite scaffold promotes osteogenic differentiation and bone regeneration.
Exosomal miR-574-3p from adipose-derived mesenchymal stem modulates CRIM1/BMPs signaling to restrain chondrocytes hypertrophy and inflammatory response in knee osteoarthritis.
Merlin controls limb development and thumb formation by regulating primary cilium-hedgehog signaling.
Three-Dimensional Bioprinted Scaffolds Loaded with Multifunctional Magnesium-Based Metal-Organic Frameworks Improve the Senescence Microenvironment Prompting Aged Bone Defect Repair.
Application of dental pulp stem cell-conditioned medium combined with deep cryopreservation of autologous cranial flaps.
α-Asarone Promotes Tendon-Bone Healing Through Regulating Dmp1 Transcription via Targeting Transcription Factor PPARG in BMSCs.
FKBP5 promotes osteogenic differentiation of mesenchymal stem cells through type-I interferon pathway Inhibition.
Low concentration of quercetin promotes BDNF expression and osteoblast differentiation during fracture healing via TrkB-ERK1/2 signaling pathway.
Activation of TFEB protects against diabetic vascular calcification by improving autophagic flux and activating Nrf2 antioxidant system.
Sequential construction of vascularized and mineralized bone organoids using engineered ECM-DNA-CPO-based bionic matrix for efficient bone regeneration.
Polyporus Umbellatus polysaccharide ameliorates rheumatoid arthritis via inhibiting inflammation and regulating gut microbiota.
p16INK4a downregulation alleviates temporomandibular joint osteoarthritis combined with type 2 diabetes by driving M2 polarization.
ED-71 ameliorates OVX-induced osteoporosis by regulating calcium homeostasis and SIRT1-mediated mitochondrial function, alleviating osteoblast senescence and suppressing osteoclastogenesis.
An Injectable Antioxidant Parathyroid Hormone Related Supramolecular Peptide Nanofiber Hydrogel for Repairing Osteoporotic Bone Defects.
EDIL3 Deficiency Attenuates Liver Fibrosis Through Inhibiting Hepatic Stellate Cells Activation via the Integrin αvβ3-ERK1/2-RUNX2 Axis in MASH Mice.
Three-Dimensional-Printed Ordered Bredigite Scaffolds with Dual Bioactivities Promote Osteochondral Regeneration.
Ionizing radiation-mediated dendritic cell maturation exacerbates inflammatory response of bone marrow mesenchymal stem cells and impairs osteogenesis in radiation-induced jaw injury.
Multiomic identification of senescent stem cell populations critical for osteoarthritis progression and therapy in subchondral bones.
Excessive accumulation of thioredoxin promotes osteogenic differentiation of mesenchymal stem cells of ligament in ankylosing spondylitis by upregulating autophagy levels.
miR-508-5p suppresses osteogenic differentiation of human periodontal ligament stem cells via targeting sex-determining region Y-related HMG-box 11.
NIR-stimulated rGO-HAMC hydrogel enhances fracture healing through regulating B-cell signaling.
Graphene Oxide Functionalized GelMA Platform Loaded With BFP-1 for Osteogenic Differentiation of BMSCs.
Copper ions-photo dual-crosslinked alginate hydrogel for angiogenesis and osteogenesis.
Comprehensive three-dimensional microCT and signaling analysis reveal the teratogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on craniofacial bone development in mice.
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
RUNX2 enhances bladder cancer progression by promoting glutamine metabolism.
RUNX2 Phase Separation Mediates Long-Range Regulation Between Osteoporosis-Susceptibility Variant and XCR1 to Promote Osteoblast Differentiation.
Low-Intensity Pulsed Ultrasound Responsive Scaffold Promotes Intramembranous and Endochondral Ossification via Ultrasonic, Thermal, and Electrical Stimulation.
The GPR30-Mediated BMP-6/HEP/FPN Signaling Pathway Inhibits Ferroptosis in Bone Marrow Mesenchymal Stem Cells to Alleviate Osteoporosis.
Astaxanthin Prevents Glucocorticoid-Induced Femoral Head Osteonecrosis by Targeting Ferroptosis through the JAK2/STAT3 Signaling Pathway.
Targeting the ALKBH5-NLRP3 positive feedback loop alleviates cardiomyocyte pyroptosis after myocardial infarction.
Whole-body vibration protects against chronic high-altitude hypoxic bone loss by regulating the nitric oxide/HIF-1α axis in osteoblasts.
PIEZO1-Primary Cilia Axis Mediates Compressive Stress-Induced Growth Plate Degeneration and Ossification in Adolescent Idiopathic Scoliosis.
3D printing combined with thermally induced phase separation for engineering hierarchical osteogenic PLA scaffolds.
Urine-derived stem cells efficiently assemble into micro-bone organoids supported by decellularized bone matrix microparticles for rapidly repairing bone defects through direct filling and paracrine functions.
Ceria nanoparticles guard against glucocorticoid induced bone homeostasis imbalance through the promotion of osteogenesis and inhibition of osteoclastogenesis.
A H(2)-bioreactor for mitochondrial rehabilitation in infected bone defects regeneration.
Photopolymerizable fish collagen peptide-GelMa composite hydrogels for dental pulp regeneration.
Near-infrared responsive nanozyme-carboxymethyl chitosan/chondroitin sulfate composite hydrogel: Multicomponent synergy optimizes bone defect microenvironment to enhance repair.
LIPUS Protects PDLSCs From Oxidative Damage and Promotes Alveolar Bone Regeneration via FOXO1.
Cuttlebone inspired "S"-grooved topological structures facilitate osteogenic differentiation through the Rap1-ERK pathway.
Shouhui Tongbian capsule promotes calcium absorption by regulating gut microbiota and protects against osteoporosis.
CKAP4 in Extracellular Vesicle-Derived From Podocyte Serves as a Non-Invasive Diagnostic Biomarker for Diabetic Nephropathy and Promotes Vascular Calcification.
Interfacial Coordination-Engineered Emulgel Modulates the Osteo-Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway-Induced Metabolic Reprogramming.
Neutrophil extracellular traps promote bone loss in type 1 diabetes via suppression of the FN1-PI3K/Akt signaling axis.
Integrative analysis reveals synergistic regulation of Sp7 by BRD9 and Wnt/β-catenin signaling during osteogenic differentiation.
Schistosoma japonicum-Derived Peptide SJMHE1 Attenuates Osteoarthritis by Promoting Synovial M2 Macrophage Polarisation.
A biomimetic multimodal nanoplatform combining neutrophil-coated two-dimensional metalloporphyrinic framework nanosheet and exendin-4 to treat obesity-related osteoporosis.
Otubain 2 stabilizes TNF‑receptor associated factor 3 to accelerate bone fracture healing.
RUNX1 Is an Independent Prognostic Marker Involved in Immune Infiltration and Therapeutic Responses in Clear Cell Renal Cell Carcinoma Patients Through Cluster Regulation With RUNX2.
TCF7L2 regulates GPX4 to resist ferroptosis and enhance osteogenesis in mouse mesenchymal stem cells.
Association of lipoprotein(a) and LPA gene with calcific aortic valve disease.
Hydroxyl safflower yellow A regulates bone-fat balance in osteoporosis by SphK1/S1P/S1PR signaling pathway.
Irisolidone enhances osteoblast differentiation via the AMPK-ULK1-autophagy Axis to accelerate osteoporotic fracture repair.
Multifunctional nanocomposite hydrogel with dual-factor controlled release for stem cell recruitment, immunomodulation and bone remodeling.
Estrogen increases Setdb1 cytoplasmic localization to stabilize Serpinh1 and improve protein homeostasis in osteoblasts.
Proteomic analysis and effects on osteogenic differentiation of exosomes from patients with ossification of the spinal ligament.
Throw out an oligopeptide to catch a protein: Deep learning and natural language processing-screened tripeptide PSP promotes Osteolectin-mediated vascularized bone regeneration.
Piezo1 exacerbates inflammation-induced cartilaginous endplate degeneration by activating mitochondrial fission via the Ca(2+)/CaMKII/Drp1 axis.
Cerium-Containing Mesoporous Bioactive Glass Nanoparticles Reinforced 3D-Printed Bioceramic Scaffolds toward Enhanced Mechanical, Antioxidant, and Osteogenic Activities for Bone Regeneration.
Ganoderic Acid A Prevented Osteoporosis by Modulating the PIK3CA/p-Akt/TWIST1 Signaling Pathway.
Exercise-Mediated Mechanical Stress Promotes Osteogenic Differentiation of BMSCs Through Upregulation of Lactylation via the IER3/LDHB Axis.
Dietary Fiber Intake Improves Osteoporosis Caused by Chronic Lead Exposure by Restoring the Gut-Bone Axis.
Polydopamine-functionalized acellular fish scale scaffolds for accelerated bone tissue regeneration.
LncRNA MRF targeting FSHR inhibits the osteogenic differentiation of BMSCs and bone defect repair through the regulation of the cAMP-PKA-CREB signaling pathway.
LncRNA NEAT1 sponges miR-214-3p to promote osteoblast differentiation through regulating the PI3K/AKT/mTOR pathway in aortic valve calcification.
Periostin Is a Candidate Regulator of the Host Microenvironment in Regeneration of Pulp and Dentin Complex and Periodontal Ligament in Transplantation with Stem Cell-Conditioned Medium.
Coaxial Electrospun Polycaprolactone/Gelatin Nanofiber Membrane Loaded with Salidroside and Cryptotanshinone Synergistically Promotes Vascularization and Osteogenesis.
IMPC-based screening revealed that ROBO1 can regulate osteoporosis by inhibiting osteogenic differentiation.
Bone-targeting engineered milk-derived extracellular vesicles for MRI-assisted therapy of osteoporosis.
Endogenous hydrogen sulfide accelerated trauma-induced heterotopic ossification through the Ca(2+)/ERK pathway-enhanced aberrant osteogenic activity.
MiR-483-3p promotes dental pulp stem cells osteogenic differentiation via the MAPK signaling pathway by targeting ARRB2.
NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease.
Nesfatin-1 mitigates calcific aortic valve disease via suppressing ferroptosis mediated by GSH/GPX4 and ZIP8/SOD2 axes.
METTL14-mediated methylation of SLC25A3 mitigates mitochondrial damage in osteoblasts, leading to the improvement of osteoporosis.
Ultrasound-triggered piezoelectric polyetheretherketone with boosted osteogenesis via regulating Akt/GSK3β/β-catenin pathway.
Salidroside alleviates simulated microgravity-induced bone loss by activating the Nrf2/HO-1 pathway.
Nitrogen-containing bisphosphonate induces enhancement of OPG expression and inhibition of RANKL expression via inhibition of farnesyl pyrophosphate synthase to inhibit the osteogenic differentiation and calcification in vascular smooth muscle cells.
Tianhe Zhuifeng Gao reverses inflammatory response and attenuates bone/cartilage destruction in rheumatoid arthritis via PSMC2-RUNX2-COL1A1 axis based on transcriptional regulatory network analysis and experimental validation.
Identification of key pathways in zirconia/dental pulp stem cell composite scaffold-mediated macrophage polarization through transcriptome sequencing.
Bazi Bushen attenuates osteoporosis in SAMP6 mice by regulating PI3K-AKT and apoptosis pathways.
Enhancing osteogenic differentiation of diabetic tendon stem/progenitor cells through hyperoxia: Unveiling ROS/HIF-1α signalling axis.
LTF ameliorates cartilage endplate degeneration by suppressing calcification, senescence and matrix degradation through the JAK2/STAT3 pathway.
Melatonin-loaded bioactive microspheres accelerate aged bone regeneration by formation of tunneling nanotubes to enhance mitochondrial transfer.
Yeast β-glucan-based nanoparticles loading methotrexate promotes osteogenesis of hDPSCs and periodontal bone regeneration under the inflammatory microenvironment.
Potential involvement of connective tissue growth factor in chondrocytes apoptosis of Kashin-Beck disease.
Preliminary study of the role of histone deacetylase (HDAC) in steroid-induced avascular necrosis of the femoral head induced by BMSC adipogenic differentiation.
Activation of BK channels prevents diabetes-induced osteopenia by regulating mitochondrial Ca(2+) and SLC25A5/ANT2-PINK1-PRKN-mediated mitophagy.
Dapagliflozin targets SGLT2/SIRT1 signaling to attenuate the osteogenic transdifferentiation of vascular smooth muscle cells.
A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repair.
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Glucagon-like peptide-1 receptor agonist exendin 4 ameliorates diabetes-associated vascular calcification by regulating mitophagy through the AMPK signaling pathway.
The multi-protective effect of IL-37-Smad3 against ox-LDL induced dysfunction of endothelial cells.
β-Receptor blocker enhances the anabolic effect of PTH after osteoporotic fracture.
Alpha-lipoic Acid Prevents Bone Loss in Type 2 Diabetes and Postmenopausal Osteoporosis Coexisting Conditions by Modulating the YAP/Glut4 Pathway.
SNHG1 knockdown promotes osteogenic differentiation of hDFSCs through anti-oxidative stress mediated by autophagy.
High phosphate and calcium induce osteoblastic phenotype switching and calcification of corneal epithelial cells in a Runx2-dependent and synergistic manner; a possible mechanism of chronic kidney disease-associated corneal calcification.
Unraveling the mechanism in l-Caldesmon regulating the osteogenic differentiation of PDLSCs: An innovative perspective.
3D-Printed Biomimetic Hydroxyapatite Composite Scaffold Loaded with Curculigoside for Rat Cranial Defect Repair.
The nano-artificial periosteum made of PCL/MgO/AS-IV enhances MC3T3-E1 cell osteogenic differentiation and promotes bone defect repair via the EphB4/EphrinB2 signaling pathway.
Sr-Incorporated Bioactive Glass Remodels the Immunological Microenvironment by Enhancing the Mitochondrial Function of Macrophage via the PI3K/AKT/mTOR Signaling Pathway.
Effects of tetrahedral DNA nanostructures on the treatment of osteoporosis.
PM(2.5) exposure inhibits osteoblast differentiation by increasing the ubiquitination and degradation of Smad4.
Influence of METTL3 knockdown on PDLSC osteogenesis in E. coli LPS-induced inflammation.
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway.
Pectolinarigenin ameliorates osteoporosis via enhancing Wnt signaling cascade in PPARβ-dependent manner.
Mitochondria-Targeted Natural Antioxidant Nanosystem for Diabetic Vascular Calcification Therapy.
Dendrobine Ameliorates Glucocorticoid-Induced Osteoporosis by Promoting Osteogenesis through JNK/p38 MAPK Pathway Activation and GR Nuclear Translocation Inhibition.
CircTOP1 targeted regulation of PTBP1 expression promotes the progression of coronary artery calcification.
KLF2/PPARγ axis contributes to trauma-induced heterotopic ossification by regulating mitochondrial dysfunction.
Carp scales derived double cross-linking hydrogels achieve collagen peptides sustained-released for bone regeneration.
Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid.
Engineered extracellular vesicle-delivered TGF-β inhibitor for attenuating osteoarthritis by targeting subchondral bone.
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Inhibition of valve mesenchymal stromal cell calcium deposition by bFGF through alternative polyadenylation regulation of the CAT gene.
Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2.
PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis.
Scaffold loaded LPS-hUCMSC-sEVs promote Osteo/odontogenic differentiation and angiogenic potential of hDPSCs.
NIR Laser Irradiation Promotes Osteogenic Differentiation of PDLSCs Through the Activation of TRPV1 Channels and Subsequent Calcium Signaling.
Foxk1 promotes bone formation through inducing aerobic glycolysis.
LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts.
Osteoinductivity enhancement by tailoring the surface chemical bond status: A strategy to mobilize host bone growth factors for in situ bone regeneration.
Honeycomb Bionic Graphene Oxide Quantum Dot/Layered Double Hydroxide Composite Nanocoating Promotes Osteoporotic Bone Regeneration via Activating Mitophagy.
Single-cell RNA transcriptomics reveals Du-Zhong-Wan promotes osteoporotic fracture healing via YAP/β-catenin/VEGF axis in BMSCs.
Magnesium-Based Composite Calcium Phosphate Cement Promotes Osteogenesis and Angiogenesis for Minipig Vertebral Defect Regeneration.
Acetyl-11-keto-β-boswellia acid attenuates Ti particle-induced osteoblastic oxidative stress and osteolysis through the Foxo3 signaling pathway.
Icariin suppresses osteogenic differentiation and promotes bone regeneration in Porphyromonas gingivalis-infected conditions through EphA2-RhoA signaling pathway.
Integrative bioinformatics and experimental analysis of curcumin's role in regulating ferroptosis to combat osteoporosis.
Controllable All-in-One Biomimetic Hollow Nanoscaffold Initiating Pyroptosis-Mediated Antiosteosarcoma Targeted Therapy and Bone Defect Repair.
Vaspin facilitates the proliferation and osteogenic differentiation of periodontal ligament stem cells.
SCD2 Regulation Targeted by miR-200c-3p on Lipogenesis Alleviates Mesenchymal Stromal Cell Senescence.
USP36 regulates the proliferation, survival, and differentiation of hFOB1.19 osteoblast.
A parathyroid hormone related supramolecular peptide for multi-functionalized osteoregeneration.
Longitudinal skeletal growth and growth plate morphological characteristics of chondro-tissue specific CUL7 knockout mice.
Improving osseointegration and antimicrobial properties of titanium implants with black phosphorus nanosheets-hydroxyapatite composite coatings for vascularized bone regeneration.
SGMS1 facilitates osteogenic differentiation of MSCs and strengthens osteogenesis-angiogenesis coupling by modulating Cer/PP2A/Akt pathway.
Tailored apoptotic vesicles promote bone regeneration by releasing the osteoinductive brake.
Fructose Potentiates Bone Loss and Marrow Adipose Tissue Accumulation by Inhibiting Adenosine 5'-Monophosphate-Activated Protein Kinase in Mesenchymal Stem Cells.
Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal.
Extracellular vesicles secreted by human gingival mesenchymal stem cells promote bone regeneration in rat femoral bone defects.
Hypoxia-inducible factor activation promotes osteogenic transition of valve interstitial cells and accelerates aortic valve calcification in a mice model of chronic kidney disease.
Single-cell transcriptomic analysis identifies a highly replicating Cd168(+) skeletal stem/progenitor cell population in mouse long bones.
Effect of sulfonation time on physicochemical, osteogenic, antibacterial properties and biocompatibility of carbon fiber reinforced polyether ether ketone.
Thioredoxin-1 promotes the restoration of alveolar bone in periodontitis with diabetes.
lncRNA MEG3 Promotes Osteogenic Differentiation of Tendon Stem Cells Via the miR-129-5p/TCF4/β-Catenin Axis and thus Contributes to Trauma-Induced Heterotopic Ossification.
PTP1B knockdown alleviates BMSCs senescence via activating AMPK-mediated mitophagy and promotes osteogenesis in senile osteoporosis.
Icariin promotes osteogenic differentiation through the mmu_circ_0000349/mmu-miR-138-5p/Jumonji domain-containing protein-3 axis.
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
5-(3',4'-dihydroxyphenyl)-γ-valerolactone, a microbiota metabolite of flavan-3-ols, activates SIRT1-mediated autophagy to attenuate H₂O₂-induced inhibition of osteoblast differentiation in MC3T3-E1 cells.
STING contributes to trauma-induced heterotopic ossification through NLRP3-dependent macrophage pyroptosis.
LncRNA H19 mediates BMP9-induced angiogenesis in mesenchymal stem cells by promoting the p53-Notch1 angiogenic signaling axis.
KLF9 Promotes Osteogenic Differentiation of Dental Stem Cells by Negatively Regulating Notch1 Mediated Signaling Pathway.
BMAL1 Promotes Valvular Interstitial Cells' Osteogenic Differentiation through NF-κ B/AKT/MAPK Pathway.
Saturated fatty acid promotes calcification via suppressing SIRT6 expression in vascular smooth muscle cells.
Tanshinone I alleviates steroid-induced osteonecrosis of femoral heads and promotes angiogenesis: in vivo and in vitro studies.
Activation of Piezo1 promotes osteogenic differentiation of aortic valve interstitial cell through YAP-dependent glutaminolysis.
Circulating miR-107 as a diagnostic biomarker of osteoporotic vertebral compression fracture increases bone formation in vitro and in vivo.
Withaferin A inhibits breast cancer-induced osteoclast differentiation.
3D Printed Biomimetic Metamaterials with Graded Porosity and Tapering Topology for Improved Cell Seeding and Bone Regeneration.
Accelerated Bone Reconstruction by the Yoda1 Bilayer Membrane via Promotion of Osteointegration and Angiogenesis.
Exosomes promote hFOB1.19 proliferation and differentiation via LINC00520.
Dysfunction of Caveolae-Mediated Endocytic TβRI Degradation Results in Hypersensitivity of TGF-β/Smad Signaling in Osteogenesis Imperfecta.
Calcium Phosphate Bone Cements Incorporated with Black Phosphorus Nanosheets Enhanced Osteogenesis.
Cannabidiol Rescues TNF-α-Inhibited Proliferation, Migration, and Osteogenic/Odontogenic Differentiation of Dental Pulp Stem Cells.
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Atf7ip Inhibits Osteoblast Differentiation via Negative Regulation of the Sp7 Transcription Factor.
Electrospun sandwich mesh structures loaded with naringenin and vitamin K(2) polycaprolactone/gelatin nanofibers synergistically promote bone regeneration.
The pterostilbene-dihydropyrazole derivative Ptd-1 ameliorates vascular calcification by regulating inflammation.
Nodakenin alleviates ovariectomy-induced osteoporosis by modulating osteoblastogenesis and osteoclastogenesis.
The Synergistic Effect of Zuogui Pill and Eldecalcitol on Improving Bone Mass and Osteogenesis in Type 2 Diabetic Osteoporosis.
LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs.
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
A bioactive glass functional hydrogel enhances bone augmentation via synergistic angiogenesis, self-swelling and osteogenesis.
Human urine-derived stem cell exosomes delivered via injectable GelMA templated hydrogel accelerate bone regeneration.
Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis.
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.
DNA Polymerase Gamma Recovers Mitochondrial Function and Inhibits Vascular Calcification by Interacted with p53.
Sinomenine Inhibits Orthodontic Tooth Movement and Root Resorption in Rats and Enhances Osteogenic Differentiation of PDLSCs.
Identification of Polysaccharides From Dipsacus asperoides and Their Effects on Osteoblast Proliferation and Differentiation in a High-Glucose Environment.
Quercetin Attenuates Osteoporosis in Orchiectomy Mice by Regulating Glucose and Lipid Metabolism via the GPRC6A/AMPK/mTOR Signaling Pathway.
The mechanosensitive Piezo1 channels contribute to the arterial medial calcification.
Effect of condylar chondrocyte exosomes on condylar cartilage osteogenesis in rats under tensile stress.
Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.
Downregulation of miR-30b-5p Facilitates Chondrocyte Hypertrophy and Apoptosis via Targeting Runx2 in Steroid-Induced Osteonecrosis of the Femoral Head.
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
Hesperetin, a Promising Dietary Supplement for Preventing the Development of Calcific Aortic Valve Disease.
Selenium-sensitive histone deacetylase 2 is required for forkhead box O3A and regulates extracellular matrix metabolism in cartilage.
Knockdown of circHIPK3 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells through activating the autophagy flux.
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
Effects of runt-related transcription factor 2 (RUNX2) on the autophagy of rapamycin-treated osteoblasts.
Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes.
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
Sustained release of naringin from silk-fibroin-nanohydroxyapatite scaffold for the enhancement of bone regeneration.
SPARC-related modular calcium binding 1 regulates aortic valve calcification by disrupting BMPR-II/p-p38 signalling.
A periodontal tissue regeneration strategy via biphasic release of zeolitic imidazolate framework-8 and FK506 using a uniaxial electrospun Janus nanofiber.
Ubiquitin-specific protease 47 is associated with vascular calcification in chronic kidney disease by regulating osteogenic transdifferentiation of vascular smooth muscle cells.
A silk fibroin/chitosan/nanohydroxyapatite biomimetic bone scaffold combined with autologous concentrated growth factor promotes the proliferation and osteogenic differentiation of BMSCs and repair of critical bone defects.
Nanosilica-Anchored Polycaprolactone/Chitosan Nanofibrous Bioscaffold to Boost Osteogenesis for Bone Tissue Engineering.
Downregulating MFN2 Promotes the Differentiation of Induced Pluripotent Stem Cells into Mesenchymal Stem Cells through the PI3K/Akt/GSK-3β/Wnt Signaling Pathway.
MFN2 knockdown promotes osteogenic differentiation of iPSC-MSCs through aerobic glycolysis mediated by the Wnt/β-catenin signaling pathway.
Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.
LINC00370 modulates miR-222-3p-RGS4 axis to protect against osteoporosis progression.
Total glycosides from Eucommia ulmoides seed promoted osteogenic differentiation of adipose-derived mesenchymal stem cells and bone formation in ovariectomized rats through regulating Notch signaling pathway.
miR-142a-5p promoted osteoblast differentiation via targeting nuclear factor IA.
Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization.
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
A polydopamine-assisted strontium-substituted apatite coating for titanium promotes osteogenesis and angiogenesis via FAK/MAPK and PI3K/AKT signaling pathways.
The effects of Omarigliptin on promoting osteoblastic differentiation.
The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway.
The p53/miR-145a Axis Promotes Cellular Senescence and Inhibits Osteogenic Differentiation by Targeting Cbfb in Mesenchymal Stem Cells.
Rosamultin Attenuates Acute Hypobaric Hypoxia-Induced Bone Injuries by Regulation of Sclerostin and Its Downstream Signals.
Celastrol attenuates arterial and valvular calcification via inhibiting BMP2/Smad1/5 signalling.
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement.
VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I.
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.
Effects Of Triptolide On Tooth Movement And Root Resorption In Rats.
Enhancement of tenogenic differentiation of rat tendon-derived stem cells by biglycan.
TMEM18 inhibits osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells by inactivating β-catenin.
ZnO nanoparticles inhibit the activity of Porphyromonas gingivalis and Actinomyces naeslundii and promote the mineralization of the cementum.
MicroRNA‑223 promotes osteoblast differentiation of MC3T3‑E1 cells by targeting histone deacetylase 2.
Potential Role of H-Ferritin in Mitigating Valvular Mineralization.
Histone demethylase KDM7A reciprocally regulates adipogenic and osteogenic differentiation via regulation of C/EBPα and canonical Wnt signalling.
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
Hypoxia Triggers Osteochondrogenic Differentiation of Vascular Smooth Muscle Cells in an HIF-1 (Hypoxia-Inducible Factor 1)-Dependent and Reactive Oxygen Species-Dependent Manner.
Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification.
LncRNA ODIR1 inhibits osteogenic differentiation of hUC-MSCs through the FBXO25/H2BK120ub/H3K4me3/OSX axis.
Inhibition of pyroptosis attenuates Staphylococcus aureus-induced bone injury in traumatic osteomyelitis.
The microRNA-10a/ID3/RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament.
Aryl Hydrocarbon Receptor Antagonists Mitigate the Effects of Dioxin on Critical Cellular Functions in Differentiating Human Osteoblast-Like Cells.
The effect of different hydroxyapatite microparticles on the osteogenic differentiation of MC3T3-E1 preosteoblasts.
Angiopoietin-like 2 has auxo-action in atherosclerosis by promoting atherosclerotic calcification.
APE1/Ref-1 Inhibits Phosphate-Induced Calcification and Osteoblastic Phenotype Changes in Vascular Smooth Muscle Cells.
Effect of pioglitazone on the calcification of rat vascular smooth muscle cells through the downregulation of the Wnt/β‑catenin signaling pathway.
Graphene/single-walled carbon nanotube hybrids promoting osteogenic differentiation of mesenchymal stem cells by activating p38 signaling pathway.
The In Vitro and In Vivo Osteogenic Capability of the Extraction Socket-Derived Early Healing Tissue.
Osteogenic differentiation of human lens epithelial cells might contribute to lens calcification.
Resveratrol Ameliorated Vascular Calcification by Regulating Sirt-1 and Nrf2.
Hydrogen peroxide prevents vascular calcification induced ROS production by regulating Nrf-2 pathway.
The Role and Mechanism of α-Klotho in the Calcification of Rat Aortic Vascular Smooth Muscle Cells.
Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways.
Kou T, Wang J, Zhou J, Cheng Y, Xu L, Xie J, Chen Y, Zhang T, Zhao S, Ying Y, Xin X, Xu X, Lu D, Hu X, Qiu C, Wang J, Cheng G, Lei S, Lyu Q, Pan Y, Cao T
Computational and structural biotechnology journal 2026;31:436-447
Computational and structural biotechnology journal 2026;31:436-447
Spatholobus suberectus Stem-Derived Extracellular Vesicle-Like Particles Attenuate Glucocorticoid-Induced Osteoporosis via NRF2/HO-1 Signaling.
Chen G, Li H, Chen R, Yao Y, Lian G, Bai L, Chen H, Zhang C, Chen G
International journal of nanomedicine 2026;21:585928
International journal of nanomedicine 2026;21:585928
Magnesium-doped bioactive glass enhances bone regeneration by reversing replicative senescence of human dental pulp stem cells in bone defect therapy.
Yan X, Li X, Zhang Q, He X, Chen Q, Mai S
Regenerative biomaterials 2026;13:rbaf105
Regenerative biomaterials 2026;13:rbaf105
Quercetin attenuates tendon stem/progenitor cell senescence and promotes aged tendon repair via AKT/NF-κB/NLRP3-mediated mitophagy activation.
Wang H, Gao YC, Ming-Zhang, Dai GC, Lu PP, Li YJ, Cao MM, Liu XY, Sheng RW, Shi L, Zhang C, Cui WG, Rui YF
Journal of advanced research 2026 May;83:741-758
Journal of advanced research 2026 May;83:741-758
Farnesol Targets the GSTP1/MAPK Axis to Inhibit Trauma-Induced Tendon Heterotopic Ossification.
Deng X, Li T, Li G, Zhu T, Kong Y, Fu B, Li JJ, Chen C, Lei W, Jiang G, Zhang K
Phytotherapy research : PTR 2026 May;40(5):2692-2709
Phytotherapy research : PTR 2026 May;40(5):2692-2709
Isoliquiritigenin restores bone homeostasis in osteoporotic rats by enhancing BMSCs osteogenesis via ERK1/2-mTOR-HIF-1α-glycolytic axis and suppressing inflammation.
Chang H, Li Y, Wang Z, Fang Z, Chen H, Xu C, Jiao X, Gan Y
International immunopharmacology 2026 May 1;176:116440
International immunopharmacology 2026 May 1;176:116440
Small molecule HCY-NBD stabilizes GSTM2 via cys174 sulfenylation to attenuate high glucose induced endothelial cell senescence and calcification.
Zhang Y, Dong X, Yan X, Zhao C, Chi X, Zhao B, Miao J, Hong F, Lin Z
Redox biology 2026 Mar;90:104058
Redox biology 2026 Mar;90:104058
Osteoblast-derived osteomodulin restrains osteoclastogenesis via ITGB8/RRM2-mediated reduction of mitochondrial respiration and mitochondrial ATP production.
Jiang X, Chen H, Hou W, Dai C, Zhang R, Chen E, Zhang J, Wu W, Xu J, Chen M, Liu L, Tan X, Ji X, Wu X, Wang K, Yu C, Yu X, Li W, Zhang W
Experimental & molecular medicine 2026 Mar;58(3):879-897
Experimental & molecular medicine 2026 Mar;58(3):879-897
Magnesium ion implantation enhances the osseointegration and vascularization of 3D-Printed CoCrMo alloy scaffolds for load-bearing orthopedic applications.
Dong Z, Gao C, Wang X, Zhang T, Geng X, Chen J, Feng J, Zheng Y, Zhang Y, Han Z, Wang H, Tan J, Zhang X, Li Y, Li Z, Wei C, Cai Q, Tian H
Bioactive materials 2026 Mar;57:676-693
Bioactive materials 2026 Mar;57:676-693
SLIT3/ROBO1 axis contributes to angiogenic-osteogenic coupling in endothelial progenitor cells and peripheral blood mesenchymal stem cells.
Rong Q, Ma L, Wang M, Liu Q, Zhang Y, Yuan Z, Tan X
Stem cell research & therapy 2026 Mar 8;17(1)
Stem cell research & therapy 2026 Mar 8;17(1)
Identification of hub targets involved in carotid atherosclerosis through bioinformatics and machine learning approaches.
Jia L, Bian C, Chen Y, Zhao Y, Yang B, Sun S, Luo T
BMC cardiovascular disorders 2026 Mar 18;26(1)
BMC cardiovascular disorders 2026 Mar 18;26(1)
Microfluidic Encapsulation of Genetically Engineered Bone-marrow-derived Mesenchymal Stem Cells for Bone Defect Healing.
Ding W, Luo Z, Che J, Gan J, Zhao Y
Advanced healthcare materials 2026 Mar 15;:e05260
Advanced healthcare materials 2026 Mar 15;:e05260
Kaempferide alleviates glucocorticoid-induced osteoporosis by targeting ferroptosis through the GSK3β/Nrf-2/GPX4 pathway.
Wu ZH, Han LJ, Zhang JX, Lin YZ, Fang X, Guo YF, Jin C, Guo XS, Chen L
International immunopharmacology 2026 Jun 15;179:116601
International immunopharmacology 2026 Jun 15;179:116601
A multimodal ROS logic-gated therapeutic platform disrupts the vicious cycle of senescence to promote aged bone defect repair.
Sun X, Xie S, Fang Y, Zhang D, Wang W, Sun Z, Lu J, Yue X, Kong W, Fu D, Xu X, Dai K, Wang J, Wei J, Sun X
Bioactive materials 2026 Jul;61:692-711
Bioactive materials 2026 Jul;61:692-711
A composite sustained-release system with immunomodulatory and synergistic osteogenic differentiation effects for repairing inflammatory alveolar bone defects.
Lv T, Chen Y, Li N, Heng Y, Su X, Zhang Y, Jiang Y, Guo Y, Hu K
Biomaterials advances 2026 Jul;184:214837
Biomaterials advances 2026 Jul;184:214837
From Cells to Animals: Connexin43 Suppression Enhances Autophagic Flux to Restore Odontogenesis in Inflamed Dental Pulp.
Hu P, Chen Y, Long P, Zhang A, Lan X, He Y, Li G, Li S
International endodontic journal 2026 Jan;59(1):134-152
International endodontic journal 2026 Jan;59(1):134-152
Calpeptin promotes osteogenesis through the Dlx3-RUNX2 pathway: in vitro and in vivo evidence for a dual-action osteoporosis therapy.
Liu P, Zhang Z, Lin X, Chen Y, Sun T, Guo W
Journal of drug targeting 2026 Jan;34(1):138-149
Journal of drug targeting 2026 Jan;34(1):138-149
Yigu Decoction polysaccharides mediate gut microbiota and metabolites to promote bone formation-related protein expression and improve osteoporosis.
Zhang R, Yan K, Wu Z, Li G, Cheng F, Chen H, Zhang Y, Ge L, Chen Z, Chen T, Yao X
International journal of biological macromolecules 2026 Jan;336:149301
International journal of biological macromolecules 2026 Jan;336:149301
Suppression of distal-less homeobox 3 increased alveolar bone mass in mouse tooth socket by targeting thrombospondin 1.
Diao C, Li F, Sun K, Yu M, Liu H, Feng H, Liu Y, Han D
Journal of dental sciences 2026 Jan;21(1):115-124
Journal of dental sciences 2026 Jan;21(1):115-124
Melatonin promotes osteogenic differentiation of BMSCs by regulating circZFAND1/miR-433-3p/DKK1 pathway through melatonin receptor-dependent m6A modification of circZFAND1.
Shi Y, Yu J, Wu Y, Fang H, Yang B
Bone 2026 Jan;202:117691
Bone 2026 Jan;202:117691
An Injectable, Osteoconductive Gelatin-Enabled GelMA/HAp Hydrogel Scaffold for Minimally Invasive Bone Tissue Engineering.
Li J, Xiang N, Che L, Wu J, Song D
Bioengineering (Basel, Switzerland) 2026 Jan 26;13(2)
Bioengineering (Basel, Switzerland) 2026 Jan 26;13(2)
Calcium carbonate supplementation exacerbated gut microenvironment disruption in senile osteoporosis mice.
Chen J, Liu J, Xu M, Fu Q, Si H
iScience 2026 Jan 16;29(1):114530
iScience 2026 Jan 16;29(1):114530
Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection.
Chen H, Wei L, Yu Q, Wang C, Fan H, Li M, Dong R, Ma Y, Jiang J, Deng L, Wu MX, Lu M
Nature communications 2026 Jan 13;17(1):1613
Nature communications 2026 Jan 13;17(1):1613
Development of a Gelatin-Based Composite Hydrogel Powder with Kaolin and Sr-Doped Hydroxyapatite for Dual Hemostatic and Osteogenic Potential.
Jiang Y, Liang X
ACS omega 2026 Jan 13;11(1):1279-1292
ACS omega 2026 Jan 13;11(1):1279-1292
Pilose antler peptide enhances diabetic fracture healing by modulating the CREB-Smad2/3-Runx2 signaling axis.
Wang X, Chen Y, Cheng Z, Cao Z, Cheng S, Xin C, Zhang J, Zhang F, Chen Y, Wang J, Li S, Li Y, Wang W
Journal of ethnopharmacology 2026 Jan 10;354:120514
Journal of ethnopharmacology 2026 Jan 10;354:120514
FBXO5 alleviates apical periodontitis by facilitating TP53 protein degradation.
Zhang R, Xiong M, Li B, Sheng L, Zhang B, Wang M, Liu J
International dental journal 2026 Feb;76(1):103948
International dental journal 2026 Feb;76(1):103948
Biomineralization-inspired scaffolds using citrate-based polymers to stabilize amorphous calcium phosphate promote osteogenesis and angiogenesis for bone defect repair.
Chen J, Xian G, Xiao Z, Ge F, Yuan S, Li B, Liang X, Cai Z, Zhang N, Zhang L, Li ZA, Deng L, Zeng C, Xie D
Bioactive materials 2026 Feb;56:260-276
Bioactive materials 2026 Feb;56:260-276
Autophagy-induced osteoblast-derived exosomes maintain bone formation and prevent osteoporosis by remodeling gut microbiota-metabolism.
Chen L, Lu L, Fan C, Zhu X, Pan L, Tang S, Wang Y, Peng Y, You L
Biomedical journal 2026 Feb;49(1):100870
Biomedical journal 2026 Feb;49(1):100870
Bilayer Hydrogel Scaffold with Directional Micro-Channels and Mechanical Gradient to Promote Osteochondral Repair.
Liu Y, Xu W, Zhao D, Li Y, Guo Z, Yuan L, Gao W, Han D, Ye C
Advanced healthcare materials 2026 Feb;15(6):e03547
Advanced healthcare materials 2026 Feb;15(6):e03547
WTAP Contributes to Periodontitis Pathogenesis by Promoting PDLSC Senescence and Impairing Osteogenic Differentiation via m6A-Dependent Regulation of TP53BP1.
Xiong M, Wang T, Liu Y
Immunity, inflammation and disease 2026 Feb;14(2):e70335
Immunity, inflammation and disease 2026 Feb;14(2):e70335
A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
Ren Z, Wu Z, Wu A, Zhang H, Lu J, Zhang J, Weng J, Zhang J, Chen S, Tan H, Guo T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18807
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18807
A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation.
Huang Y, Zhang Y, Feng Y, Yang Q, Gao B, Xu H, Huang C, Lin K, Xu Y, Zhu P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e18796
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e18796
Transgenic high expression of EphB4 in canine periodontal ligament stem cells modulates osteogenic differentiation and migration in cPDLSCs.
Li CS, Zhang X, Liu H, Feng Y, Wang L, Zhou M, Xie NN, Zhu SY
Biomedical engineering online 2026 Feb 9;25(1)
Biomedical engineering online 2026 Feb 9;25(1)
Kaempferol Alleviates Glucocorticoid-Induced Osteonecrosis of the Femoral Head by Modulating Macrophage M1/M2 Polarization Through RhoA/ROCK-Mediated Mitophagy Activation.
Zhang Y, Zhao Y, Zhang S, Lei T, Xiang B, Zhang X, Nan K, Fan L
Biomedicines 2026 Feb 9;14(2)
Biomedicines 2026 Feb 9;14(2)
MECP2 Insufficiency Attenuates RUNX2-Dependent Osteoblast Differentiation via miR-126-3p/DKK1-Mediated Canonical Wnt Signaling Inhibition in Rett Syndrome.
Dong S, Wang L, Kato H, Hirofuji S, Zhou Z, Ito Y, Hirofuji Y, Sato H, Kato TA, Sakai Y, Ohga S, Fukumoto S, Masuda K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71570
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71570
Psoralen Promotes Direct Chemical Reprogramming of Mouse Embryonic Fibroblasts into Osteoblast-like Cells.
Li W, Liu H, Wan X, Cheng D, Zhu R, Zhang Z
Pharmaceutics 2026 Feb 23;18(2)
Pharmaceutics 2026 Feb 23;18(2)
Supramolecular delivery of senolytics enables targeted anti-senescence therapy and accelerated fracture healing.
Fan Y, Wang ZH, Zhang X, Dong Y, Liu X, Luo G, Yang H, Li H, Wang Z, Tang Q, Jin X, Guo DS, Sun T
Journal of nanobiotechnology 2026 Feb 18;24(1)
Journal of nanobiotechnology 2026 Feb 18;24(1)
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Shen Y, Zhang M, Yang T, Wu Y, Qiu Y, Zhang L, Li F, Chen M, Chen Q, Wei W, Li H, Shen Y
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Cellular & molecular biology letters 2026 Feb 11;31(1):22
BMP2@PDA-LDH functionalized coating on ZK60 magnesium alloy: Enhanced corrosion resistance and promoted bone defect regeneration.
Wang T, Zhou W, Li S, Le K, Zhang X, Wang J, Xie S, Wan Y, Xi W
Colloids and surfaces. B, Biointerfaces 2026 Aug;264:115650
Colloids and surfaces. B, Biointerfaces 2026 Aug;264:115650
Bioinspired scaffold recapitulating chondrogenic ontogeny and microenvironment for functional cartilage regeneration.
Yu T, Sun X, Liu Y, Dou Y, Tian Y, Zhang Y, Wang G, Wang L, Han J, Li X, Cheng X, Li H, Pan H, Yang L, Zhao Y, Yang Q
Bioactive materials 2026 Apr;58:531-549
Bioactive materials 2026 Apr;58:531-549
3D-printed titanium scaffolds coated with a multifunctional photothermal-responsive hydrogel promote osteoporotic bone defect repair.
Wang C, Wang Y, Li X, Cao H, Wang C, Han S, Chen H, Zhao X, Yang S
Materials today. Bio 2026 Apr;37:102879
Materials today. Bio 2026 Apr;37:102879
The multilayer coatings on polylactic acid implants spatiotemporally regulates the microenvironment to enhance antibacterial and osseointegration capacity.
Lyu J, Jiang S, Ma T, Zhang Y, Yu J, Zhang Z, Teng Z, Helili M, Cao S, Geng X, Wang X, Jiang J, Qiu J, Sun X, Liu X, Ma X
Materials today. Bio 2026 Apr;37:102871
Materials today. Bio 2026 Apr;37:102871
A dual-functional Janus nanofibrous membrane as an immunomodulatory barrier for periodontitis regeneration under diabetic conditions.
Wang F, Wang Y, Sheng J, Zhang K, Cao Y, Han X, Yan K, Wang X
Materials today. Bio 2026 Apr;37:102869
Materials today. Bio 2026 Apr;37:102869
Tannic acid-assisted mechanical training transforms natural hydrogels into robust and bioactive membranes for guided bone regeneration.
Sun J, Wang X, Wang X, Yu W, Yu Y, Ge S, Dong Z
Materials today. Bio 2026 Apr;37:102863
Materials today. Bio 2026 Apr;37:102863
Graphene oxide coating on two-dimensional glass substrates and three-dimensional zirconia scaffolds for bone tissue regeneration.
Liu K, Tian Y, Mu R, Wang X, Xin M, Ding H, Qian Y, Hu Z, Zeng C, Wei X, Shuai Y, Jin L
Materials today. Bio 2026 Apr;37:102852
Materials today. Bio 2026 Apr;37:102852
Ultrasound-activated piezoelectric Silk-PVDF hydrogel reprograms the osteoimmune microenvironment via NRF2 signaling for accelerated bone regeneration.
Mo G, Qing L, Zhang C, Huang L, Yan H, Lu S, Zhang Y, Chen W, Xiang X, Wang N, Han G, Li Y, Jiang L, Zhang J
Materials today. Bio 2026 Apr;37:102779
Materials today. Bio 2026 Apr;37:102779
Polyhedral oligomeric silsesquioxane-functionalized carboxymethyl chitin microspheres via irradiation-induced grafting for hemostasis and tissue repair in post-extraction sockets.
Zhao XY, Lei S, Yan M, Jiang X, Zhang YJ, Liu J, Yang MX, Li LG, Wang CY, Xie C, Li TF, Leng F
International journal of biological macromolecules 2026 Apr;358:151727
International journal of biological macromolecules 2026 Apr;358:151727
Dual-release 3D-printed porous Ti-6Al-4V implant with drug-eluting photothermal micro-nanotopographies: combating osteosarcoma recurrence, infections, and enhancing osteogenesis.
Ji Z, Wan Y, Zou Y, Wang H, Liang X, Liu P
Biomaterials 2026 Apr;327:123749
Biomaterials 2026 Apr;327:123749
Identification and Screening of Lactate-Related Genes as Molecular Markers for Early Diagnosis of Steroid-Induced Osteonecrosis of the Femoral Head.
Wang Z, Dong S, Xu K, Tang X, Guo S, Jiang Y, Zhang Y, Li T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71793
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71793
UHRF1-mediated DNA 5-mC modification drives super-enhancer redistribution and impedes osteogenesis via TGM2-regulated autophagic flux in senile osteoporosis.
Pang P, Chen J, Li Q, Su Z, Lin J, Zeng Y, Zhang W, Xiao Z, Chen Z, Liu Z, Lin Y, Zheng G, Yu W, Xie Z
Journal of advanced research 2026 Apr 17;
Journal of advanced research 2026 Apr 17;
Synergistic Antibacterial and Osteogenic Activities of Cu/Sr-Empowered 13-93 Bioglass in PMMA Composites for Sequential Promotion of Infectious Osseointegration.
Li Y, Yu J, Dong Z, Feng Y, Hou X, Xing B
ACS applied materials & interfaces 2026 Apr 15;18(14):20228-20246
ACS applied materials & interfaces 2026 Apr 15;18(14):20228-20246
Vericiguat improves CKD-related vascular calcification through the NO/cGMP/PKG pathway.
Li C, Li J, Yang C, Zhu Z, Zhang Y, Xiang Y
International immunopharmacology 2026 Apr 15;175:116413
International immunopharmacology 2026 Apr 15;175:116413
Dual improvement effects of ω-3 on bone loss and liver injury in rats with liver-bone axis damage.
Huang J, Chen L, Yu H, Zhou S, Guan J, Xu C
Food & function 2026 Apr 14;17(7):3229-3247
Food & function 2026 Apr 14;17(7):3229-3247
Biphasic Scaffolds Functionalized with Piezoelectric Nanozymes for Osteochondral Defect Regeneration.
Ding H, Zhao C, Hu Y, Tong C, Gong X, Yang Y, Fang Y, Li J, Dai S, Chen W, Dong S
Advanced healthcare materials 2026 Apr 1;:e00012
Advanced healthcare materials 2026 Apr 1;:e00012
Functionalized Periosteum-Derived Microsphere-Hydrogel with Sequential Release of E7 Short Peptide/miR217 for Large Bone Defect Repairing.
Yao J, Zu D, Dong Q, Xia J, Wang X, Guo J, Ma G, Wu B, Fang B
Biomaterials research 2025;29:0127
Biomaterials research 2025;29:0127
Core transcriptional regulatory circuitry molecule ZNF217 promotes AML cell proliferation by up-regulating MYB.
Zhou B, Fang F, Zhang Y, Li Z, Hu Y, Li Y, Jiao W, Wu Y, Wan X, Yang Y, Zhang F, Xu L, Ji T, Pan J, Hu S
International journal of biological sciences 2025;21(5):1966-1983
International journal of biological sciences 2025;21(5):1966-1983
Imbalance of Bone Homeostasis Caused by Nrf2 Deficiency Leads to Bone Loss in OVX Rats.
Sun P, Wang Z, Chen S, Chen X, Zhou F, Zhang C, Yang J, Huang Y, Lin Y
Stem cells international 2025;2025:7214250
Stem cells international 2025;2025:7214250
Effects and mechanisms of engineered exosomes pretreated with Scutellaria baicalensis Georgi on osteoporosis.
Long C, Li X, Fan Y, Hu Y, He W, Hu N, He F
PloS one 2025;20(10):e0333897
PloS one 2025;20(10):e0333897
Salidroside Improves Periodontitis by Mitigating Inflammatory Reactions and Enhancing Osteogenic Differentiation of Human Periodontal Ligament Stem Cells.
Li W, Liu Q, Chen S, Zhi M, Yang P, Zhang Y, Wu Z, Zhang J, Feng Q
Drug design, development and therapy 2025;19:8097-8114
Drug design, development and therapy 2025;19:8097-8114
Exosomes derived from Panax notoginseng promote osteogenic differentiation of rBMSCs via the PI3K/AKT signaling pathway.
Wu N, Zhang L, Guo H
Frontiers in pharmacology 2025;16:1682548
Frontiers in pharmacology 2025;16:1682548
Single-cell RNA-seq reveals a repair pattern in cystic lesions in steroid induced osteonecrosis of the femoral head.
Peng P, Tian J, Lin K, Fang W, Yao F, Yang X, Hou W, Xiao F, Lu S, He W, He M, Xiao H, Wei Q
Frontiers in immunology 2025;16:1626337
Frontiers in immunology 2025;16:1626337
Scorpion-Centipede extracts mitigate ovariectomy-induced osteoporosis in mice through facilitating Cx3cr1 expression.
Ni J, Yu L, Wang B, Chen S, Shang W, Fang P, Du B, Min W
Frontiers in pharmacology 2025;16:1604096
Frontiers in pharmacology 2025;16:1604096
Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/β-catenin signaling pathway.
Tian Y, Liu H, Bao X, Li Y
Frontiers in pharmacology 2025;16:1539411
Frontiers in pharmacology 2025;16:1539411
Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.
Mo Y, Jin A, Hong W, Peng J, Yang R, Song Q, Liu Y, Cheng Y, Wong WT, Huang Q, Jiang L, Xu Z, Tan N
Frontiers in bioengineering and biotechnology 2025;13:1636883
Frontiers in bioengineering and biotechnology 2025;13:1636883
Zirconia/dental pulp stem cell composite scaffolds repair osteogenic defect via regulating macrophages.
Wu Y, He M, Li C, Shang W, Hu J, Liu B
Frontiers in bioengineering and biotechnology 2025;13:1632000
Frontiers in bioengineering and biotechnology 2025;13:1632000
Shockwave-driven activation of endoplasmic reticulum stress in osteoblasts to enhance bone formation under osteoporotic conditions.
Luo D, Chen Q, Xiao Z, Feng C, Hu R, Wang Y, Zhu C, Yang X, Liu L, Li X, Zhu X, Song Y, Zhang X
Regenerative biomaterials 2025;12:rbaf069
Regenerative biomaterials 2025;12:rbaf069
A pH-sensitive CuHP composite hydrogel featuring antibacterial, antioxidant and osteogenic properties for treating diabetic periodontitis.
Lu X, Hu S, Zhang Z, Bao J, Cao B, Xie J, Chang J, Yang C, Wang X, Su J
Regenerative biomaterials 2025;12:rbaf065
Regenerative biomaterials 2025;12:rbaf065
Spatiotemporal regulation of the bone immune microenvironment via a 'Zn(2+)-quercetin' hierarchical delivery system for bone regeneration.
Sun H, Chen Y, Sang X, Liu Q, Yu H, Hu S, Mao Y, Zhang L
Regenerative biomaterials 2025;12:rbaf006
Regenerative biomaterials 2025;12:rbaf006
Osmotic stress inhibits osteoblast differentiation and mineralization by suppressing TRPV4-mediated calcium influx.
Miyano T, Hasegawa H, Sera T
Journal of bone and mineral metabolism 2025 Sep;43(5):477-492
Journal of bone and mineral metabolism 2025 Sep;43(5):477-492
METTL14 promotes TBK1 mRNA stability through IGF2BP3-recognized m6A modification and enhances mitophagy in BMSCs.
Shen Y, Wang L, Guo Z, Wang J, Zhang R, Tang C, Wu J
Cellular signalling 2025 Sep;133:111873
Cellular signalling 2025 Sep;133:111873
Zingerone treats postmenopausal osteoporosis via increased ferroptosis sensitivity by p53-mediated regulation of SAT1 and GPX4 expression.
Li H, Cao F, Liu D, Tao L
Communications biology 2025 Sep 26;8(1):1367
Communications biology 2025 Sep 26;8(1):1367
Transcription factor RUNX2 participates in astrocyte-mediated neuropathic pain via transcriptional activation of Ccl2.
Shen W, Song S, Zhao X, Li D, Liu J, Yue S
Biochemical and biophysical research communications 2025 Sep 1;777:152263
Biochemical and biophysical research communications 2025 Sep 1;777:152263
4-Octyl Itaconate Attenuates Postmenopausal Osteoporosis by Inhibiting Ferroptosis and Enhancing Osteogenesis via the Nrf2 Pathway.
Li Y, Li Y, Li P, Yang L, Li H
Inflammation 2025 Oct;48(5):3326-3339
Inflammation 2025 Oct;48(5):3326-3339
Dual stimulus-responsive dECM cryogel sequentially regulate bone microenvironment for one-step surgical therapy of chronic osteomyelitis.
Liu H, Liu S, Liao L, Liao H, Pan W, Hu J
Materials today. Bio 2025 Oct;34:102243
Materials today. Bio 2025 Oct;34:102243
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
Ming P, Li K, Zhu W
Materials today. Bio 2025 Oct;34:102236
Materials today. Bio 2025 Oct;34:102236
TGF-β1/IL-11 positive loop between renal tubular epithelial cell and fibroblast promotes the ectopic calcification of renal interstitial fibroblasts in rats.
Zhong J, Duan X, Yang H, Liu Z, Zhong W, Zhang Z, Huang Y, Zeng H, Zhao H, Liu Y, Liu Y, Zeng G, Zhao Z
Biochemical pharmacology 2025 Oct;240:117074
Biochemical pharmacology 2025 Oct;240:117074
POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?
Liu H, Li X, Li M, Sun Z, Wang X, Li J, Xu B, Chen Q, Fan C, Ruan H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e07951
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e07951
PIEZO1-GPX4 Axis Mediates Mechanical Stress-Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation.
Chen F, Peng F, Chen S, Du Y, Li J, Fan Y, Cui Z, Gu G, Zhang H, Jiang Z, Wang G, Jing X, Dong J, Li T, Xi Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e02052
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e02052
Rabbits as preclinical animal models of cam morphology: proof of concept.
Li Z, Wan P, Liu X, Jiang G, Li J, Chen D, Zhang W, Tian K
BMC musculoskeletal disorders 2025 Oct 6;26(1):918
BMC musculoskeletal disorders 2025 Oct 6;26(1):918
Genotype and phenotype correlation analysis in 27 families with multiple osteochondroma and validation by ATDC5 chondrocyte models.
Guo X, Lin M, Xu S, Liu B, Zhang R, Liu S, Pan Y
Bone & joint research 2025 Oct 27;14(10):901-914
Bone & joint research 2025 Oct 27;14(10):901-914
Pak4-mediated crosstalk between necroptotic macrophages and tendon stem/progenitor cells contributes to traumatic heterotopic ossification formation.
Sun Z, Liu H, Xu Y, Chen Q, Luo G, Yuan Z, Chen Z, He K, Fan C, Li J, Ruan H
Bone research 2025 Oct 20;13(1):88
Bone research 2025 Oct 20;13(1):88
M2-exo promote orthodontic bone remodeling via the MeCP2-TCF20-HDAC1 axis.
Chen M, Li Y, Yang Z, Chen M, Li J, Bao G, Ma L, Hu J
Stem cell research & therapy 2025 Oct 15;16(1):569
Stem cell research & therapy 2025 Oct 15;16(1):569
The impact of catalpol on osteogenic differentiation of the jaw bone marrow mesenchymal stem cells on the basis of network pharmacology, molecular docking and experimental validation.
Tang R, Liu H, Guo X, Xiao Y, Li K, Deng X, Li Q, Zhou J
BMC oral health 2025 Oct 14;25(1):1613
BMC oral health 2025 Oct 14;25(1):1613
Orally administered degradable nanoarmor-assisted probiotics for remodeling the gut microenvironment and treating osteoporosis.
Li Z, Deng X, Qiu C, Wang Z, Tang F, Pi Y, He Z, Zheng C, Luo J
Journal of nanobiotechnology 2025 Oct 11;23(1):660
Journal of nanobiotechnology 2025 Oct 11;23(1):660
H3K18 lactylation-hexokinase 2 positive feedback loop promotes osteogenesis of ASPCs in facial infiltrating lipomatosis.
Chen H, Hua C, Chang SJ, Qiu Y, Lin X, Sun B
Stem cell research & therapy 2025 Oct 1;16(1):538
Stem cell research & therapy 2025 Oct 1;16(1):538
Targeting SIRT3 to regulate mitophagy-dependent ferroptosis for preventing glucocorticoid-induced osteoporosis.
Hu Y, Lu H, Fang H, Chen B, Chen Z, Jiang M, Zhou Y, Li Z, Gao S, Huang Z, Zhou C, Liu Y, Chen Z, Fan Y
International journal of surgery (London, England) 2025 Oct 1;111(10):6647-6662
International journal of surgery (London, England) 2025 Oct 1;111(10):6647-6662
Nano-assisted dynamically assembled hydrogels with strong tissue adhesion and proactive immunomodulation for bone defect repair.
Chen X, Li W, Ma Y, Zhang W, He W, Ding F, Guo S, Geng D, Pan G
Bioactive materials 2025 Nov;53:480-494
Bioactive materials 2025 Nov;53:480-494
Autophagic damage in senescent bone marrow mesenchymal stromal cells: Impact on Piezo1 expression during osteoporosis progression.
Huang C, Chen X, Wu D, Chen J, Wang J, Li S, Hu J, Yan Z, Zhu Y, Zhang Y
International journal of biological macromolecules 2025 Nov;330(Pt 1):147928
International journal of biological macromolecules 2025 Nov;330(Pt 1):147928
Timosaponin B- II Enhances Osteogenic Differentiation of Human Periodontal Ligament Stem Cells via PI3K/AKT/GSK3β Signaling Pathway.
Yang DW, Cui XB, Dong R, Wu ZY, Zhang YX, Yang P, Zhang J
Stem cell reviews and reports 2025 Nov;21(8):2675-2692
Stem cell reviews and reports 2025 Nov;21(8):2675-2692
Moderate-intensity exercise attenuates bone loss in hyperuricemic nephropathic mice.
Chen L, Xie R, Cen Z, Zou J, Liu B, Liu G, Zhang Y, Yuan Y, Yang L
Bone 2025 Nov;200:117603
Bone 2025 Nov;200:117603
Virulence-Selective Trap-Capture-Kill Antibacterial Nanostructures With Immune-Metabolic Regulation for Treating Implant-Associated Infections.
Hu X, Zhong J, Chen Y, Liu B, Du T, Zhu W, Zheng M, Liang H, Ni J, Peng Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e11045
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e11045
Histone H3K18 lactylation-dependent epigenetic activation of RUNX2 orchestrates PI3K/AKT oncogenic signaling in laryngeal squamous cell carcinoma.
Fu D, Huang X, Lin Y, Yu F, Wu H
Journal of molecular histology 2025 Nov 4;56(6):361
Journal of molecular histology 2025 Nov 4;56(6):361
Kaempferol ameliorates BMSCs senescence in postmenopausal osteoporosis by targeting Sp1 to activate FUNDC1-mediated mitophagy.
Wang L, Qu Y, Hu Z, Lei P, Tian X, Yang X, Chen S, Li C, Wei B, Li L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157456
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157456
Farnesyltransferase inhibitors decrease matrix-vesicle-mediated mineralization in SaOS-2 cells.
Bürgel T, Diehl D, van Lier EC, Friedmann A, Hagemann A, Bachmann HS
Molecular biology reports 2025 Nov 19;53(1):99
Molecular biology reports 2025 Nov 19;53(1):99
Modulation of Osteogenic Differentiation by CYBB in Osteoporotic Models.
Wang Z, Xu C, Liu Y, Duan K, Zhu Z, Guan J
IUBMB life 2025 May;77(5):e70023
IUBMB life 2025 May;77(5):e70023
Cranial repair-promoting effect of oxidised sodium alginate/amino gelatine injectable hydrogel loaded with deer antler blood peptides.
Yu T, Ding Q, Wang N, Zhang S, Cheng Z, Zhao C, Li Q, Ding C, Liu W
International journal of biological macromolecules 2025 May;305(Pt 1):141116
International journal of biological macromolecules 2025 May;305(Pt 1):141116
YTHDF3 regulates IL32 mRNA stability to promote osteogenic differentiation of bone mesenchymal stem cells in ankylosing spondylitis.
Zhou B, Feng X, Han C, Wu Y, Qiao J, Tong W, Xu W
Journal of translational medicine 2025 May 30;23(1):604
Journal of translational medicine 2025 May 30;23(1):604
An Asymmetric Zn Membrane with Degradability, Antimicrobial, and Bone Immunomodulation for Guided Bone Regeneration.
Ma S, Zhao Z, Shang Y, Qi M, Xu S, Yao S, Li Y, Wang X, Tong T, Zheng H, Ma B, Yang Y, Wu J, Liu Z, Deng J
ACS applied materials & interfaces 2025 May 28;17(21):31640-31653
ACS applied materials & interfaces 2025 May 28;17(21):31640-31653
SEC24D depletion induces osteogenic differentiation deficiency by inactivating the ATF6/TGF-β/Runx2 regulatory loop.
Zhang J, Yang K, Chen WQ, Sun DL, Hu HY, Li Q, Yan YS, Li YZ, Yin CH, Guo Q
Communications biology 2025 May 15;8(1):758
Communications biology 2025 May 15;8(1):758
Accelerated differentiation of photothermal effect-induced mesenchymal stem cells regulated by activating HSP90-autophagy boosts wound repair.
Li XY, Ding DP, Zhan MY, Ma TQ, Zhao XY, Zheng L, Han N, Leng F, Mao YC, Li Z, Wei W, Tan Y, Tang JM, Li TF
International journal of pharmaceutics 2025 May 15;676:125631
International journal of pharmaceutics 2025 May 15;676:125631
METTL3 promotes osteogenesis by regulating N6-methyladenosine-dependent primary processing of hsa-miR-4526.
Song Y, Gao H, Pan Y, Gu Y, Sun W, Liu J
Stem cells (Dayton, Ohio) 2025 May 15;43(5)
Stem cells (Dayton, Ohio) 2025 May 15;43(5)
The surface protein Gbp of Fusobacterium nucleatum inhibits osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2.
Dong R, Li M, Gu XF, Gao H, Wei Z, Qi H, Zhang J, Feng Q
Journal of translational medicine 2025 May 14;23(1):540
Journal of translational medicine 2025 May 14;23(1):540
Transcription factor SMAD5 upregulates ALG5 to alleviate osteoporosis development by inducing osteogenic differentiation.
Li Z, Liu Y, Wang H, Xu G
Journal of orthopaedics 2025 Mar;61:140-149
Journal of orthopaedics 2025 Mar;61:140-149
Methacrylated silk fibroin based composite hydrogel with ROS-scavenging and osteogenic ability to orchestrate diabetic bone regeneration.
Wang R, He X, Su S, Bai J, Liu H, Zhou F
International journal of biological macromolecules 2025 Mar;294:138945
International journal of biological macromolecules 2025 Mar;294:138945
5,7-Dihydroxy-4-Methylcoumarin enhances osteogenesis and ameliorates osteoporosis via the AKT1 pathway.
Diao H, Yang H, Yu B, Fan Y, Li S, Fan J, Xiao D, Zhao Y, Guo M, Zhang Y, Huang S, Tang Q, Li SS, Sun T, Jin X
Biochemical pharmacology 2025 Mar;233:116752
Biochemical pharmacology 2025 Mar;233:116752
Ginsenoside Rg1 regulating inflammatory response and bone-remodeling through Keap1/Nrf2 signaling pathway in rats with periodontitis.
Zhou Y, Zhang Y, Wang L, Liu Y, Wang Z, Guo L
Scientific reports 2025 Mar 3;15(1):7478
Scientific reports 2025 Mar 3;15(1):7478
Mechanistic Insights into Salvigenin for Glucocorticoid-Induced Femoral Head Osteonecrosis: A Network Pharmacology and Experimental Study.
Zhu Z, Zhong Y, He R, Zhong C, Chen J, Peng H
Biomedicines 2025 Mar 3;13(3)
Biomedicines 2025 Mar 3;13(3)
METTL3-mediated m6A modification of circSTAT6 modulates miR-188-3p/Beclin1 axis to promote osteogenic differentiation of mesenchymal stem cells.
Luo Y, Shi Y, Wu Y, Cao H
Journal of orthopaedic surgery and research 2025 Mar 26;20(1):313
Journal of orthopaedic surgery and research 2025 Mar 26;20(1):313
miR-138-5p inhibits healing of femoral fracture osteogenesis in rats by modulating osteoblast differentiation via SIRT1/FOXO1 axis.
Dai G, Jiang W, Feng B, Zhang L
Journal of orthopaedic surgery and research 2025 Mar 14;20(1):280
Journal of orthopaedic surgery and research 2025 Mar 14;20(1):280
Static Topographical Cue Combined with Dynamic Fluid Stimulation Enhances the Macrophage Extracellular Vesicle Yield and Therapeutic Potential for Bone Defects.
Huang H, Xiao L, Fang L, Lei M, Liu Z, Gao S, Lei Q, Lei J, Wei R, Lei Y, Xue L, Geng Z, Cai L, Yan F
ACS nano 2025 Mar 11;19(9):8667-8691
ACS nano 2025 Mar 11;19(9):8667-8691
GIT2 negatively regulates the NF-κB pathway directly or indirectly by regulating TRAF3 expression to promote osteogenic differentiation of BMSCs.
Wang Y, Wang C, Gong Y, Li Q, Liu M, Sun H
Tissue & cell 2025 Jun;94:102790
Tissue & cell 2025 Jun;94:102790
The effects of FOXC2-gene-manipulated human periodontal ligament stem cells on bone regeneration of craniofacial bone defect.
Chen Y, Zhang X, Tang Y, Yang Y, Wu Z, Lai W, Long H
Dental materials : official publication of the Academy of Dental Materials 2025 Jun;41(6):708-720
Dental materials : official publication of the Academy of Dental Materials 2025 Jun;41(6):708-720
CBD-conjugated BMP-inhibiting exosomes on collagen scaffold dual-target Achilles tendon repair: Synergistic regeneration and heterotopic ossification prevention.
Xu Y, Huang J, Mai Y, Zhang Z, Li S, Lin H, Wei F, Chen Y
Materials today. Bio 2025 Jun;32:101790
Materials today. Bio 2025 Jun;32:101790
A novel strategy for bone defect repair: Stromal cell-derived factor 1α sustained-release acellular fish scale scaffolds combined with injection of bone marrow mesenchymal stem cells promote bone regeneration.
Su S, Bai J, Wang R, Gao S, Zhou R, Zhou F
Materials today. Bio 2025 Jun;32:101759
Materials today. Bio 2025 Jun;32:101759
Harnessing engineered exosomes as METTL3 carriers: Enhancing osteogenesis and suppressing lipogenesis in bone marrow mesenchymal stem cells for postmenopausal osteoporosis treatment.
Li T, Zhao J, Yuan J, Ding R, Yang G, Cao J, Zhao X, Liu J, Liu Y, Xu P, Deng J, Miao X, Cheng X
Materials today. Bio 2025 Jun;32:101648
Materials today. Bio 2025 Jun;32:101648
Targeted Delivery of α-ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes.
Wang J, Cao J, Zhang S, Chen H, Yu X, Wang X, Wang T, Cao W, Dong W, Lin X, Li J, Lei W, Feng Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2415667
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2415667
Icariin-loaded composite scaffold promotes osteogenic differentiation and bone regeneration.
Jin DS, Zhao ZH, Ruan SQ, Huang WL, Tian RY, Wan Y, Deng J
BMC musculoskeletal disorders 2025 Jun 3;26(1):548
BMC musculoskeletal disorders 2025 Jun 3;26(1):548
Exosomal miR-574-3p from adipose-derived mesenchymal stem modulates CRIM1/BMPs signaling to restrain chondrocytes hypertrophy and inflammatory response in knee osteoarthritis.
Kang J, Zhang L, Zhang L, Nan N, Liu Y, Hao H
International immunopharmacology 2025 Jun 26;159:114916
International immunopharmacology 2025 Jun 26;159:114916
Merlin controls limb development and thumb formation by regulating primary cilium-hedgehog signaling.
Wu S, Bian Y, Zhang C, Liu K, Sun F, Chen E, Zhou C, Yu L, Chen G, Wu M
Cell reports 2025 Jun 24;44(6):115849
Cell reports 2025 Jun 24;44(6):115849
Three-Dimensional Bioprinted Scaffolds Loaded with Multifunctional Magnesium-Based Metal-Organic Frameworks Improve the Senescence Microenvironment Prompting Aged Bone Defect Repair.
Sun X, Xu X, Zhao X, Ma J, Wang T, Yue X, Sun X, Li X, Sun X, Zhang W, Zhang K, Zhang D, Zhao X, Jin W, Wang J
ACS nano 2025 Jun 24;19(24):22141-22162
ACS nano 2025 Jun 24;19(24):22141-22162
Application of dental pulp stem cell-conditioned medium combined with deep cryopreservation of autologous cranial flaps.
Liu Y, Liu Y, Ye Z, Wang X, Li J, Mei PL, Duan L, Wang B, Xu C, Xiong W, He Y, Ye Q
Stem cell research & therapy 2025 Jun 2;16(1):272
Stem cell research & therapy 2025 Jun 2;16(1):272
α-Asarone Promotes Tendon-Bone Healing Through Regulating Dmp1 Transcription via Targeting Transcription Factor PPARG in BMSCs.
Li T, Li G, Deng X, Zhu T, Li JJ, Chen C, Jia J, Zhang S, Zhang K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70701
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70701
FKBP5 promotes osteogenic differentiation of mesenchymal stem cells through type-I interferon pathway Inhibition.
Tang J, Li M, Chen Y, Liang Y, Yan W, Ning Q, Deng H, Liu H, Li Y, Huang L
Cellular and molecular life sciences : CMLS 2025 Jun 14;82(1):236
Cellular and molecular life sciences : CMLS 2025 Jun 14;82(1):236
Low concentration of quercetin promotes BDNF expression and osteoblast differentiation during fracture healing via TrkB-ERK1/2 signaling pathway.
Meng X, Chen X, Meng W, Han C, Qian X, Zhang Z
Experimental cell research 2025 Jun 1;449(1):114569
Experimental cell research 2025 Jun 1;449(1):114569
Activation of TFEB protects against diabetic vascular calcification by improving autophagic flux and activating Nrf2 antioxidant system.
Sun XJ, Xiao SJ, Ma WQ, Jin H, Ren LQ, Yao YY, Chen ZD, Li XX, Chen T, Liu NF
American journal of physiology. Endocrinology and metabolism 2025 Jun 1;328(6):E924-E939
American journal of physiology. Endocrinology and metabolism 2025 Jun 1;328(6):E924-E939
Sequential construction of vascularized and mineralized bone organoids using engineered ECM-DNA-CPO-based bionic matrix for efficient bone regeneration.
Gai T, Zhang H, Hu Y, Li R, Wang J, Chen X, Wang J, Chen Z, Jing Y, Wang C, Bai L, Wang X, Su J
Bioactive materials 2025 Jul;49:362-377
Bioactive materials 2025 Jul;49:362-377
Polyporus Umbellatus polysaccharide ameliorates rheumatoid arthritis via inhibiting inflammation and regulating gut microbiota.
Zheng Z, Dai J, Pan X, Xiang J, You P, Zhang H, Luo L
International journal of biological macromolecules 2025 Jul;318(Pt 4):145306
International journal of biological macromolecules 2025 Jul;318(Pt 4):145306
p16INK4a downregulation alleviates temporomandibular joint osteoarthritis combined with type 2 diabetes by driving M2 polarization.
Cai J, Zhang L, Du Q, Wang M, Ma X, Chen Y, Wang Y, Yuan H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jul;188:118172
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jul;188:118172
ED-71 ameliorates OVX-induced osteoporosis by regulating calcium homeostasis and SIRT1-mediated mitochondrial function, alleviating osteoblast senescence and suppressing osteoclastogenesis.
Zhang Y, Cui Y, Sun C, Guo J, Li M
Cellular signalling 2025 Jul;131:111713
Cellular signalling 2025 Jul;131:111713
An Injectable Antioxidant Parathyroid Hormone Related Supramolecular Peptide Nanofiber Hydrogel for Repairing Osteoporotic Bone Defects.
Feng Q, Li H, Wang Y, Wang J, Zhang Z, Hao Z, Chen R, Chen T, Shi G, Chen J, Zhu T, Du J, Hu Y, Li J
ACS applied materials & interfaces 2025 Jul 9;17(27):38890-38911
ACS applied materials & interfaces 2025 Jul 9;17(27):38890-38911
EDIL3 Deficiency Attenuates Liver Fibrosis Through Inhibiting Hepatic Stellate Cells Activation via the Integrin αvβ3-ERK1/2-RUNX2 Axis in MASH Mice.
Wei C, Lu D, Liu J, Qin JJ, Wang M, Lei F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70862
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70862
Three-Dimensional-Printed Ordered Bredigite Scaffolds with Dual Bioactivities Promote Osteochondral Regeneration.
Zhao L, Yang S, Zhang X, Feng G, Lu J, Zhang Z
ACS applied materials & interfaces 2025 Jul 23;17(29):41707-41718
ACS applied materials & interfaces 2025 Jul 23;17(29):41707-41718
Ionizing radiation-mediated dendritic cell maturation exacerbates inflammatory response of bone marrow mesenchymal stem cells and impairs osteogenesis in radiation-induced jaw injury.
Zheng M, Chen H, Liu Z, Wang Z, Jiang T, He Y
Stem cell research & therapy 2025 Jul 18;16(1):388
Stem cell research & therapy 2025 Jul 18;16(1):388
Multiomic identification of senescent stem cell populations critical for osteoarthritis progression and therapy in subchondral bones.
Li PL, Tang J, Li XT, Zhao SR, Xu RX, Zhao ZD, Li ZL, Li ZL, Yin BF, Yu FH, Wu CT, Zhu H
Science advances 2025 Jul 18;11(29):eadu2294
Science advances 2025 Jul 18;11(29):eadu2294
Excessive accumulation of thioredoxin promotes osteogenic differentiation of mesenchymal stem cells of ligament in ankylosing spondylitis by upregulating autophagy levels.
Qiao J, Zhou B, Han C, Xu Q, Feng X, Xu W
Biochemical and biophysical research communications 2025 Jan;745:151255
Biochemical and biophysical research communications 2025 Jan;745:151255
miR-508-5p suppresses osteogenic differentiation of human periodontal ligament stem cells via targeting sex-determining region Y-related HMG-box 11.
Guo J, Ouyang XY, Liu JR, Liu WY, Wang YB
Journal of dental sciences 2025 Jan;20(1):201-211
Journal of dental sciences 2025 Jan;20(1):201-211
NIR-stimulated rGO-HAMC hydrogel enhances fracture healing through regulating B-cell signaling.
Yang HZ, Zhan Y, Liu Y, Guo M, Fan Y, Luo G, Zhao Y, Huang S, Sun T, Li SS, Ye Q, Jin X
Biomaterials advances 2025 Jan;166:214080
Biomaterials advances 2025 Jan;166:214080
Graphene Oxide Functionalized GelMA Platform Loaded With BFP-1 for Osteogenic Differentiation of BMSCs.
Guo T, Lin S, Zou L, Zhang G, Long J, Zhang Z, Wang S
Journal of biomedical materials research. Part A 2025 Jan;113(1):e37829
Journal of biomedical materials research. Part A 2025 Jan;113(1):e37829
Copper ions-photo dual-crosslinked alginate hydrogel for angiogenesis and osteogenesis.
Liu G, Ye S, Li Y, Yang J, Wang S, Liu Y, Yang S, Tian Y, Yin M, Cheng B
Journal of biomedical materials research. Part A 2025 Jan;113(1):e37790
Journal of biomedical materials research. Part A 2025 Jan;113(1):e37790
Comprehensive three-dimensional microCT and signaling analysis reveal the teratogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on craniofacial bone development in mice.
Wang XM, Qin CM, Li D, Xu XR, Pan XJ, Xue H
Ecotoxicology and environmental safety 2025 Jan 15;290:117743
Ecotoxicology and environmental safety 2025 Jan 15;290:117743
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Xie J, Huang H, Xu S, Zhou K, Chen X, Fang J, Zhao F
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
RUNX2 enhances bladder cancer progression by promoting glutamine metabolism.
Huang Z, Liu B, Li X, Jin C, Hu Q, Zhao Z, Sun Y, Wang Q
Neoplasia (New York, N.Y.) 2025 Feb;60:101120
Neoplasia (New York, N.Y.) 2025 Feb;60:101120
RUNX2 Phase Separation Mediates Long-Range Regulation Between Osteoporosis-Susceptibility Variant and XCR1 to Promote Osteoblast Differentiation.
Zhang Y, Li XH, Peng P, Qiu ZH, Di CX, Chen XF, Wang NN, Chen F, He YW, Liu ZB, Zhao F, Zhu DL, Dong SS, Hu SY, Yang Z, Li YP, Guo Y, Yang TL
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(6):e2413561
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(6):e2413561
Low-Intensity Pulsed Ultrasound Responsive Scaffold Promotes Intramembranous and Endochondral Ossification via Ultrasonic, Thermal, and Electrical Stimulation.
Jia W, Wang T, Chen F, Liu Z, Hou X, Cao W, Zhao X, Lu B, Hu Y, Dong Y, Zhou J, Zhou Z, Zhan W
ACS nano 2025 Feb 4;19(4):4422-4439
ACS nano 2025 Feb 4;19(4):4422-4439
The GPR30-Mediated BMP-6/HEP/FPN Signaling Pathway Inhibits Ferroptosis in Bone Marrow Mesenchymal Stem Cells to Alleviate Osteoporosis.
Chen S, Xiao J, Zhou S, Wumiti T, Zhao Z, Zhao R, Pan Y, Wang Q, Ma Y, Wu L, Guo Y
International journal of molecular sciences 2025 Feb 26;26(5)
International journal of molecular sciences 2025 Feb 26;26(5)
Astaxanthin Prevents Glucocorticoid-Induced Femoral Head Osteonecrosis by Targeting Ferroptosis through the JAK2/STAT3 Signaling Pathway.
Lin YZ, Chen ZH, Yang JF, Han LJ, Yu YT, Zhan JN, Tan GC, Liu LY, Xie CL, Shan P, Jin C, Liu HX
Journal of agricultural and food chemistry 2025 Feb 19;73(7):4270-4287
Journal of agricultural and food chemistry 2025 Feb 19;73(7):4270-4287
Targeting the ALKBH5-NLRP3 positive feedback loop alleviates cardiomyocyte pyroptosis after myocardial infarction.
Cui LG, Zhai MM, Yin JJ, Wang ZM, Wang SH, Zhou YJ, Li PP, Wang Y, Xia L, Wang P, Cha XX, Zhang LR, Han SN
European journal of pharmacology 2025 Feb 15;989:177247
European journal of pharmacology 2025 Feb 15;989:177247
Whole-body vibration protects against chronic high-altitude hypoxic bone loss by regulating the nitric oxide/HIF-1α axis in osteoblasts.
Wang D, Liu R, Ding Y, Pei Q, Sun T, Shao X, Jiang M, Liu J, Huang J, Yan Z, Hao X, Jing D, Cai J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Feb 15;39(3):e70385
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Feb 15;39(3):e70385
PIEZO1-Primary Cilia Axis Mediates Compressive Stress-Induced Growth Plate Degeneration and Ossification in Adolescent Idiopathic Scoliosis.
Chen F, Chen S, Peng F, Du Y, Li J, Fan Y, Cui Z, Gu G, Zhang H, Jing X, Dong J, Li T, Xi Y
JOR spine 2025 Dec;8(4):e70133
JOR spine 2025 Dec;8(4):e70133
3D printing combined with thermally induced phase separation for engineering hierarchical osteogenic PLA scaffolds.
Yun X, Li Z, Yan Z, Li S, Dai Z, Hu J, Ren Y, Huang L, Wang Q, Zhang C, Li J, Deng C, Liu H, Zheng W, Zhong C, Zhang Z
Materials today. Bio 2025 Dec;35:102621
Materials today. Bio 2025 Dec;35:102621
Urine-derived stem cells efficiently assemble into micro-bone organoids supported by decellularized bone matrix microparticles for rapidly repairing bone defects through direct filling and paracrine functions.
Chen Y, Zhang L, Li Z, Wang X, Liu J, Wang X, Hu J, Wang G, Huang Q, Yuan Y
Materials today. Bio 2025 Dec;35:102533
Materials today. Bio 2025 Dec;35:102533
Ceria nanoparticles guard against glucocorticoid induced bone homeostasis imbalance through the promotion of osteogenesis and inhibition of osteoclastogenesis.
Zhang A, Liu Z, Zou L, Yang L, Wu Y, Wang X, Cao D, Liu J, Yang X, Zhang S
Materials today. Bio 2025 Dec;35:102308
Materials today. Bio 2025 Dec;35:102308
A H(2)-bioreactor for mitochondrial rehabilitation in infected bone defects regeneration.
Kong C, Si C, Liu H, Wang Y, Qiao J, Tang X, Sun H, Zhang J, Chang B
Materials today. Bio 2025 Dec;35:102295
Materials today. Bio 2025 Dec;35:102295
Photopolymerizable fish collagen peptide-GelMa composite hydrogels for dental pulp regeneration.
Zhao J, Yang Y, Zhang R, Xu Z, Wu L, Sun Z, Shi W, Qin B, Huang H, Chen G
International journal of biological macromolecules 2025 Dec;332(Pt 2):148628
International journal of biological macromolecules 2025 Dec;332(Pt 2):148628
Near-infrared responsive nanozyme-carboxymethyl chitosan/chondroitin sulfate composite hydrogel: Multicomponent synergy optimizes bone defect microenvironment to enhance repair.
Sun D, Ding C, Wang N, Ding Q, Liu W, Liu X, Wei H, Yang J, Cheng Z, Zhao S, Hong B, Zhao T
International journal of biological macromolecules 2025 Dec;332(Pt 1):148646
International journal of biological macromolecules 2025 Dec;332(Pt 1):148646
LIPUS Protects PDLSCs From Oxidative Damage and Promotes Alveolar Bone Regeneration via FOXO1.
Tang L, Duan Y, Yang K, Wang D, Yao H
Oral diseases 2025 Dec;31(12):3420-3436
Oral diseases 2025 Dec;31(12):3420-3436
Cuttlebone inspired "S"-grooved topological structures facilitate osteogenic differentiation through the Rap1-ERK pathway.
Sun Y, Cai Y, Xu S, Zhai N, Wang Z, Qiu Z, Han S, Wei Y, Liu R, Wu H
Biomaterials advances 2025 Dec;177:214431
Biomaterials advances 2025 Dec;177:214431
Shouhui Tongbian capsule promotes calcium absorption by regulating gut microbiota and protects against osteoporosis.
Xu M, Fu Q, Liu J, Chen J, Zhai X, Wang C, Xu W, Li L, Wang K, Si H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157520
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157520
CKAP4 in Extracellular Vesicle-Derived From Podocyte Serves as a Non-Invasive Diagnostic Biomarker for Diabetic Nephropathy and Promotes Vascular Calcification.
Zhang H, Lou K, Qian L, Zhang M, Li J, Lv L, Lu F, He G, Wu C, Wu J, Jia M, Bai Y, Qu S, Liu M, Chu L, Wang Y, Ding D, Zen K, Yuan Y, Liang H
Journal of extracellular vesicles 2025 Dec;14(12):e70208
Journal of extracellular vesicles 2025 Dec;14(12):e70208
Interfacial Coordination-Engineered Emulgel Modulates the Osteo-Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway-Induced Metabolic Reprogramming.
Zhang H, Huang X, Chen R, Lin W, Li L, Peng X, Yang X, Chen X, Guo T, Weng J, Li J, Yuan Q, Tan H, Wang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09998
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09998
Neutrophil extracellular traps promote bone loss in type 1 diabetes via suppression of the FN1-PI3K/Akt signaling axis.
Liu X, Xiao D, Zhang D, Pan Y, Guo J, Zhang Y, Li S, Tang Q, Jin X, Sun T
International immunopharmacology 2025 Dec 3;166:115629
International immunopharmacology 2025 Dec 3;166:115629
Integrative analysis reveals synergistic regulation of Sp7 by BRD9 and Wnt/β-catenin signaling during osteogenic differentiation.
Wu L, Wang L, Zhuang Y, Luo Y, Zhu Q, Maimaitizunong M, Wang Y, Cheng Z, Li Y, Sheng X, Li M, Luo Q, Jiang X, Lei S, Lin X, Zhong Y, Ren W
Communications biology 2025 Dec 1;9(1):23
Communications biology 2025 Dec 1;9(1):23
Schistosoma japonicum-Derived Peptide SJMHE1 Attenuates Osteoarthritis by Promoting Synovial M2 Macrophage Polarisation.
Zhu W, Jiang Y, Wang S, Wang X, Zhang Q, Fan W
Parasite immunology 2025 Aug;47(8):e70018
Parasite immunology 2025 Aug;47(8):e70018
A biomimetic multimodal nanoplatform combining neutrophil-coated two-dimensional metalloporphyrinic framework nanosheet and exendin-4 to treat obesity-related osteoporosis.
Yang Q, Liu J, Liu Y, Liu S, Wei X, Yang Y, Zhang W, Zhang S, Zhang M, Liu B, Wang X, Zhu D
Materials today. Bio 2025 Aug;33:102009
Materials today. Bio 2025 Aug;33:102009
Otubain 2 stabilizes TNF‑receptor associated factor 3 to accelerate bone fracture healing.
Zhang L, Guo J, Feng S, Zheng Y, Wang H, Ma H, Chen W, Zhang Y, Hou Z
Molecular medicine reports 2025 Aug;32(2)
Molecular medicine reports 2025 Aug;32(2)
RUNX1 Is an Independent Prognostic Marker Involved in Immune Infiltration and Therapeutic Responses in Clear Cell Renal Cell Carcinoma Patients Through Cluster Regulation With RUNX2.
Jian J, Zhang J, Xu H, Wang H, Hou J
Immunity, inflammation and disease 2025 Aug;13(8):e70242
Immunity, inflammation and disease 2025 Aug;13(8):e70242
TCF7L2 regulates GPX4 to resist ferroptosis and enhance osteogenesis in mouse mesenchymal stem cells.
Lei M, Liu B, Wan B, Feng Y, Teng Y, Xi D, Zeng G, Zong S
European journal of medical research 2025 Aug 5;30(1):713
European journal of medical research 2025 Aug 5;30(1):713
Association of lipoprotein(a) and LPA gene with calcific aortic valve disease.
Yu X, Fu Z, Yu M, Shi Y
European journal of medical research 2025 Aug 22;30(1):787
European journal of medical research 2025 Aug 22;30(1):787
Hydroxyl safflower yellow A regulates bone-fat balance in osteoporosis by SphK1/S1P/S1PR signaling pathway.
Xu X, Hu X, Zhou S, Liu J, Su Z, Zheng Z, Luo D
Biochemical pharmacology 2025 Aug 20;242(Pt 1):117258
Biochemical pharmacology 2025 Aug 20;242(Pt 1):117258
Irisolidone enhances osteoblast differentiation via the AMPK-ULK1-autophagy Axis to accelerate osteoporotic fracture repair.
Lao Z, Liu Z, Ji W, Chen X, Yang W, Qian Y
Biochemical pharmacology 2025 Aug 13;242(Pt 1):117234
Biochemical pharmacology 2025 Aug 13;242(Pt 1):117234
Multifunctional nanocomposite hydrogel with dual-factor controlled release for stem cell recruitment, immunomodulation and bone remodeling.
Jiao Y, Wang H, Zhao M, Liu H, Shen P, Wu G, Forouzanfar T, Tay FR, Miao L, Liu H, Liu Q
Journal of controlled release : official journal of the Controlled Release Society 2025 Aug 10;384:113893
Journal of controlled release : official journal of the Controlled Release Society 2025 Aug 10;384:113893
Estrogen increases Setdb1 cytoplasmic localization to stabilize Serpinh1 and improve protein homeostasis in osteoblasts.
Han C, Wang P, Ye J, Wang R, Shi X, Hu G, Hu X, Shen J, Zhang M, Zhang X, Wu Y
Molecular and cellular endocrinology 2025 Aug 1;605:112568
Molecular and cellular endocrinology 2025 Aug 1;605:112568
Proteomic analysis and effects on osteogenic differentiation of exosomes from patients with ossification of the spinal ligament.
Nakajima H, Johnson WEB, Kamitani M, Watanabe S, Honjoh K, Kubota A, Matsumine A
JBMR plus 2025 Apr;9(4):ziaf021
JBMR plus 2025 Apr;9(4):ziaf021
Throw out an oligopeptide to catch a protein: Deep learning and natural language processing-screened tripeptide PSP promotes Osteolectin-mediated vascularized bone regeneration.
Chen Y, Chen L, Wu J, Xu X, Yang C, Zhang Y, Chen X, Lin K, Zhang S
Bioactive materials 2025 Apr;46:37-54
Bioactive materials 2025 Apr;46:37-54
Piezo1 exacerbates inflammation-induced cartilaginous endplate degeneration by activating mitochondrial fission via the Ca(2+)/CaMKII/Drp1 axis.
Lin Z, Xu G, Lu X, Wang H, Lu F, Xia X, Song J, Jiang J, Ma X, Zou F
Aging cell 2025 Apr;24(4):e14440
Aging cell 2025 Apr;24(4):e14440
Cerium-Containing Mesoporous Bioactive Glass Nanoparticles Reinforced 3D-Printed Bioceramic Scaffolds toward Enhanced Mechanical, Antioxidant, and Osteogenic Activities for Bone Regeneration.
Zhao Z, Chen X, Chen H, Zhang J, Du L, Jiang F, Zheng K
Advanced healthcare materials 2025 Apr;14(9):e2404346
Advanced healthcare materials 2025 Apr;14(9):e2404346
Ganoderic Acid A Prevented Osteoporosis by Modulating the PIK3CA/p-Akt/TWIST1 Signaling Pathway.
Zhao J, Fan Y, Li H, Wang C, Fan S, Sun H, Liu M
Food science & nutrition 2025 Apr;13(4):e70177
Food science & nutrition 2025 Apr;13(4):e70177
Exercise-Mediated Mechanical Stress Promotes Osteogenic Differentiation of BMSCs Through Upregulation of Lactylation via the IER3/LDHB Axis.
Dai S, Chen Z, Liu X, Dong J, Zhang Z, Yang Z, Huang M, Cai L, Xiao X, Zhu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70537
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70537
Dietary Fiber Intake Improves Osteoporosis Caused by Chronic Lead Exposure by Restoring the Gut-Bone Axis.
Wang R, Shen J, Han C, Shi X, Gong Y, Hu X, Jia Z, Wang M, Wu Y
Nutrients 2025 Apr 29;17(9)
Nutrients 2025 Apr 29;17(9)
Polydopamine-functionalized acellular fish scale scaffolds for accelerated bone tissue regeneration.
Su S, Wang R, Bai J, Gao S, Zhou R, Zhou F
RSC advances 2025 Apr 28;15(18):13857-13873
RSC advances 2025 Apr 28;15(18):13857-13873
LncRNA MRF targeting FSHR inhibits the osteogenic differentiation of BMSCs and bone defect repair through the regulation of the cAMP-PKA-CREB signaling pathway.
Ning Q, Li M, Liao Z, Chen E, Liu H, Liang Y, Chen Y, Li Y, Huang L
Stem cell research & therapy 2025 Apr 23;16(1):200
Stem cell research & therapy 2025 Apr 23;16(1):200
LncRNA NEAT1 sponges miR-214-3p to promote osteoblast differentiation through regulating the PI3K/AKT/mTOR pathway in aortic valve calcification.
Xu R, Sun Y, Tian F, Zhao M
Scientific reports 2025 Apr 21;15(1):13665
Scientific reports 2025 Apr 21;15(1):13665
Periostin Is a Candidate Regulator of the Host Microenvironment in Regeneration of Pulp and Dentin Complex and Periodontal Ligament in Transplantation with Stem Cell-Conditioned Medium.
Sakatoku S, Hayashi Y, Futenma T, Sugita Y, Ishizaka R, Nawa H, Iohara K
Stem cells international 2024;2024:7685280
Stem cells international 2024;2024:7685280
Coaxial Electrospun Polycaprolactone/Gelatin Nanofiber Membrane Loaded with Salidroside and Cryptotanshinone Synergistically Promotes Vascularization and Osteogenesis.
Wu X, Liu C, Jiang Y, Dai T, Zhang L, Wang J, Zhao H
International journal of nanomedicine 2024;19:6519-6546
International journal of nanomedicine 2024;19:6519-6546
IMPC-based screening revealed that ROBO1 can regulate osteoporosis by inhibiting osteogenic differentiation.
Zhang X, Wang Y, Zheng M, Wei Q, Zhang R, Zhu K, Zhai Q, Xu Y
Frontiers in cell and developmental biology 2024;12:1450215
Frontiers in cell and developmental biology 2024;12:1450215
Bone-targeting engineered milk-derived extracellular vesicles for MRI-assisted therapy of osteoporosis.
Huang Q, Jiang Y, Cao Y, Ding Y, Cai J, Yang T, Zhou X, Wu Q, Li D, Liu Q, Li F
Regenerative biomaterials 2024;11:rbae112
Regenerative biomaterials 2024;11:rbae112
Endogenous hydrogen sulfide accelerated trauma-induced heterotopic ossification through the Ca(2+)/ERK pathway-enhanced aberrant osteogenic activity.
Yuan Z, Li J, He K, Sun Z, Luo G, Liu H, Dong J, Zhou C, Cui H, Fan C
Redox biology 2024 Sep;75:103265
Redox biology 2024 Sep;75:103265
MiR-483-3p promotes dental pulp stem cells osteogenic differentiation via the MAPK signaling pathway by targeting ARRB2.
Yu X, Ge J, Xie H, Qian J, Xia W, Wang Q, Zhou X, Zhou Y
In vitro cellular & developmental biology. Animal 2024 Sep;60(8):879-887
In vitro cellular & developmental biology. Animal 2024 Sep;60(8):879-887
NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease.
Wang H, Mao W, Zhang Y, Feng W, Bai B, Ji B, Chen J, Cheng B, Yan F
Free radical biology & medicine 2024 Sep;222:331-343
Free radical biology & medicine 2024 Sep;222:331-343
Nesfatin-1 mitigates calcific aortic valve disease via suppressing ferroptosis mediated by GSH/GPX4 and ZIP8/SOD2 axes.
Wang S, Gu J, Bian J, He Y, Xu X, Wang C, Li G, Zhang H, Ni B, Chen S, Shao Y, Jiang Y
Free radical biology & medicine 2024 Sep;222:149-164
Free radical biology & medicine 2024 Sep;222:149-164
METTL14-mediated methylation of SLC25A3 mitigates mitochondrial damage in osteoblasts, leading to the improvement of osteoporosis.
Wang P, Zhou W, Chen F, Zhang X, Zhang Q, Chen Y, Zhang N
Experimental gerontology 2024 Sep;194:112496
Experimental gerontology 2024 Sep;194:112496
Ultrasound-triggered piezoelectric polyetheretherketone with boosted osteogenesis via regulating Akt/GSK3β/β-catenin pathway.
Li Y, Fan Y, Zhao S, Cheng B
Journal of nanobiotechnology 2024 Sep 5;22(1):539
Journal of nanobiotechnology 2024 Sep 5;22(1):539
Salidroside alleviates simulated microgravity-induced bone loss by activating the Nrf2/HO-1 pathway.
Wang N, Zuo Z, Meng T, Liu Y, Zheng X, Ma Y
Journal of orthopaedic surgery and research 2024 Sep 2;19(1):531
Journal of orthopaedic surgery and research 2024 Sep 2;19(1):531
Nitrogen-containing bisphosphonate induces enhancement of OPG expression and inhibition of RANKL expression via inhibition of farnesyl pyrophosphate synthase to inhibit the osteogenic differentiation and calcification in vascular smooth muscle cells.
Xu W, Gong L, Tang W, Lu G
BMC cardiovascular disorders 2024 Sep 17;24(1):494
BMC cardiovascular disorders 2024 Sep 17;24(1):494
Tianhe Zhuifeng Gao reverses inflammatory response and attenuates bone/cartilage destruction in rheumatoid arthritis via PSMC2-RUNX2-COL1A1 axis based on transcriptional regulatory network analysis and experimental validation.
Liu X, Mao X, Chen W, Zhang Y, Li T, Wang K, Lin N, Zhang Y
International immunopharmacology 2024 Sep 10;138:112573
International immunopharmacology 2024 Sep 10;138:112573
Identification of key pathways in zirconia/dental pulp stem cell composite scaffold-mediated macrophage polarization through transcriptome sequencing.
Liu B, He M, Chen B, Shuai Y, He X, Liu K, Li J, Jin L
Biotechnology & genetic engineering reviews 2024 Oct;40(2):833-857
Biotechnology & genetic engineering reviews 2024 Oct;40(2):833-857
Bazi Bushen attenuates osteoporosis in SAMP6 mice by regulating PI3K-AKT and apoptosis pathways.
Xu Z, Zhang Z, Zhou H, Lin S, Gong B, Li Z, Zhao S, Hou Y, Peng Y, Bian Y
Journal of cellular and molecular medicine 2024 Oct;28(20):e70161
Journal of cellular and molecular medicine 2024 Oct;28(20):e70161
Enhancing osteogenic differentiation of diabetic tendon stem/progenitor cells through hyperoxia: Unveiling ROS/HIF-1α signalling axis.
Zhang M, Dai GC, Zhang YW, Lu PP, Wang H, Li YJ, Rui YF
Journal of cellular and molecular medicine 2024 Oct;28(20):e70127
Journal of cellular and molecular medicine 2024 Oct;28(20):e70127
LTF ameliorates cartilage endplate degeneration by suppressing calcification, senescence and matrix degradation through the JAK2/STAT3 pathway.
Li T, Liu Y, Cao J, Pan C, Ding R, Zhao J, Liu J, He D, Jia J, Cheng X
Journal of cellular and molecular medicine 2024 Oct;28(19):e18267
Journal of cellular and molecular medicine 2024 Oct;28(19):e18267
Melatonin-loaded bioactive microspheres accelerate aged bone regeneration by formation of tunneling nanotubes to enhance mitochondrial transfer.
Xiong H, Qiu H, Wang C, Qiu Y, Tan S, Chen K, Zhao F, Song J
Materials today. Bio 2024 Oct;28:101175
Materials today. Bio 2024 Oct;28:101175
Yeast β-glucan-based nanoparticles loading methotrexate promotes osteogenesis of hDPSCs and periodontal bone regeneration under the inflammatory microenvironment.
Chen H, Liu N, Hu S, Li X, He F, Chen L, Xu X
Carbohydrate polymers 2024 Oct 15;342:122401
Carbohydrate polymers 2024 Oct 15;342:122401
Potential involvement of connective tissue growth factor in chondrocytes apoptosis of Kashin-Beck disease.
Yang X, Liu H, Cheng S, Pan C, Cai Q, Chu X, Shi S, Wei W, He D, Cheng B, Wen Y, Jia Y, Tinkov AA, Skalny AV, Zhang F
Ecotoxicology and environmental safety 2024 Oct 15;285:117148
Ecotoxicology and environmental safety 2024 Oct 15;285:117148
Preliminary study of the role of histone deacetylase (HDAC) in steroid-induced avascular necrosis of the femoral head induced by BMSC adipogenic differentiation.
Yu YL, Duan P, Zheng L, Xu JM, Pan ZY
Journal of orthopaedic surgery and research 2024 Oct 12;19(1):645
Journal of orthopaedic surgery and research 2024 Oct 12;19(1):645
Activation of BK channels prevents diabetes-induced osteopenia by regulating mitochondrial Ca(2+) and SLC25A5/ANT2-PINK1-PRKN-mediated mitophagy.
Jiang L, He H, Tang Y, Li J, Reilly S, Xin H, Li Z, Cai H, Zhang X
Autophagy 2024 Nov;20(11):2388-2404
Autophagy 2024 Nov;20(11):2388-2404
Dapagliflozin targets SGLT2/SIRT1 signaling to attenuate the osteogenic transdifferentiation of vascular smooth muscle cells.
Li L, Liu H, Chai Q, Wei J, Qin Y, Yang J, Liu H, Qi J, Guo C, Lu Z
Cellular and molecular life sciences : CMLS 2024 Nov 9;81(1):448
Cellular and molecular life sciences : CMLS 2024 Nov 9;81(1):448
A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repair.
Wang Y, Chen Y, Zhou T, Li J, Zhang N, Liu N, Zhou P, Mao Y
Journal of nanobiotechnology 2024 Nov 13;22(1):702
Journal of nanobiotechnology 2024 Nov 13;22(1):702
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Huang L, Zhang S, Bian M, Xiang X, Xiao L, Wang J, Lu S, Chen W, Zhang C, Mo G, Jiang L, Li Y, Zhang J
Acta biomaterialia 2024 May;180:82-103
Acta biomaterialia 2024 May;180:82-103
Glucagon-like peptide-1 receptor agonist exendin 4 ameliorates diabetes-associated vascular calcification by regulating mitophagy through the AMPK signaling pathway.
Chen K, Jin HJ, Wu ZH, Zhang BF, Wu J, Huang ZY, Huang YP, Lu XW, Zheng XT
Molecular medicine (Cambridge, Mass.) 2024 May 8;30(1):58
Molecular medicine (Cambridge, Mass.) 2024 May 8;30(1):58
The multi-protective effect of IL-37-Smad3 against ox-LDL induced dysfunction of endothelial cells.
Zhang C, Huang X, Xie B, Lian D, Chen J, Li W, Lin Y, Cai X, Li J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116268
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116268
β-Receptor blocker enhances the anabolic effect of PTH after osteoporotic fracture.
Huang J, Wu T, Jiang YR, Zheng XQ, Wang H, Liu H, Wang H, Leng HJ, Fan DW, Yuan WQ, Song CL
Bone research 2024 Mar 21;12(1):18
Bone research 2024 Mar 21;12(1):18
Alpha-lipoic Acid Prevents Bone Loss in Type 2 Diabetes and Postmenopausal Osteoporosis Coexisting Conditions by Modulating the YAP/Glut4 Pathway.
Xu L, Zhang C, Bao J, Han G, Wang C, Cai Y, Xu G, Sun H, Liu M
Cell biochemistry and biophysics 2024 Jun;82(2):669-685
Cell biochemistry and biophysics 2024 Jun;82(2):669-685
SNHG1 knockdown promotes osteogenic differentiation of hDFSCs through anti-oxidative stress mediated by autophagy.
Deng L, Wu L, Chen D, Cao Y
Journal of cellular physiology 2024 Jun;239(6):e31283
Journal of cellular physiology 2024 Jun;239(6):e31283
High phosphate and calcium induce osteoblastic phenotype switching and calcification of corneal epithelial cells in a Runx2-dependent and synergistic manner; a possible mechanism of chronic kidney disease-associated corneal calcification.
Ababneh H, Tóth A, Lente G, Balogh E, Csiki DM, Nagy B Jr, Szöőr Á, Jeney V
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167171
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167171
Unraveling the mechanism in l-Caldesmon regulating the osteogenic differentiation of PDLSCs: An innovative perspective.
Li Y, Mei Z, Deng P, Zhou S, Qian A, Zhang X, Li J
Cellular signalling 2024 Jun;118:111147
Cellular signalling 2024 Jun;118:111147
3D-Printed Biomimetic Hydroxyapatite Composite Scaffold Loaded with Curculigoside for Rat Cranial Defect Repair.
Weng Y, Yuan X, Fan S, Duan W, Tan Y, Zhou R, Wu J, Shen Y, Zhang Z, Xu H
ACS omega 2024 Jun 18;9(24):26097-26111
ACS omega 2024 Jun 18;9(24):26097-26111
The nano-artificial periosteum made of PCL/MgO/AS-IV enhances MC3T3-E1 cell osteogenic differentiation and promotes bone defect repair via the EphB4/EphrinB2 signaling pathway.
Wang W, Sun DF, Cui HX, Zhang WL
Heliyon 2024 Jun 15;10(11):e32036
Heliyon 2024 Jun 15;10(11):e32036
Sr-Incorporated Bioactive Glass Remodels the Immunological Microenvironment by Enhancing the Mitochondrial Function of Macrophage via the PI3K/AKT/mTOR Signaling Pathway.
Qiu H, Xiong H, Zheng J, Peng Y, Wang C, Hu Q, Zhao F, Chen K
ACS biomaterials science & engineering 2024 Jun 10;10(6):3923-3934
ACS biomaterials science & engineering 2024 Jun 10;10(6):3923-3934
Effects of tetrahedral DNA nanostructures on the treatment of osteoporosis.
Cui W, Yang X, Dou Y, Du Y, Ma X, Hu L, Lin Y
Cell proliferation 2024 Jul;57(7):e13625
Cell proliferation 2024 Jul;57(7):e13625
PM(2.5) exposure inhibits osteoblast differentiation by increasing the ubiquitination and degradation of Smad4.
Yang J, Han C, Ye J, Hu X, Wang R, Shen J, Li L, Hu G, Shi X, Jia Z, Qu X, Liu H, Zhang X, Wu Y
Toxicology letters 2024 Jul;398:127-139
Toxicology letters 2024 Jul;398:127-139
Influence of METTL3 knockdown on PDLSC osteogenesis in E. coli LPS-induced inflammation.
Chen H, Peng L, Wang Z, He Y, Zhang X
Oral diseases 2024 Jul;30(5):3225-3238
Oral diseases 2024 Jul;30(5):3225-3238
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway.
Wu X, Fu Y, Ma J, Li C, He A, Zhang T
Tissue engineering and regenerative medicine 2024 Jul;21(5):791-807
Tissue engineering and regenerative medicine 2024 Jul;21(5):791-807
Pectolinarigenin ameliorates osteoporosis via enhancing Wnt signaling cascade in PPARβ-dependent manner.
Qian J, Li Q, Song Y, Gong X, Hu K, Ge G, Sun Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155587
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155587
Mitochondria-Targeted Natural Antioxidant Nanosystem for Diabetic Vascular Calcification Therapy.
Li J, Lan T, Guo Q, Zhang C, Lu X, Hu X, Shen X, Zhang Y
Biomacromolecules 2024 Jul 8;25(7):4329-4343
Biomacromolecules 2024 Jul 8;25(7):4329-4343
Dendrobine Ameliorates Glucocorticoid-Induced Osteoporosis by Promoting Osteogenesis through JNK/p38 MAPK Pathway Activation and GR Nuclear Translocation Inhibition.
Li X, Gao C, Zhou K, Gan K, Ye T, Zhao J, Li J, Ma C
Journal of agricultural and food chemistry 2024 Jul 31;72(30):16739-16748
Journal of agricultural and food chemistry 2024 Jul 31;72(30):16739-16748
CircTOP1 targeted regulation of PTBP1 expression promotes the progression of coronary artery calcification.
Hu H, Shen S, Wu J, Ma L
Experimental cell research 2024 Jul 15;440(2):114147
Experimental cell research 2024 Jul 15;440(2):114147
KLF2/PPARγ axis contributes to trauma-induced heterotopic ossification by regulating mitochondrial dysfunction.
Sun Z, Liu H, Hu Y, Luo G, Yuan Z, Liu W, Tu B, Ruan H, Li J, Fan C
Cell proliferation 2024 Jan;57(1):e13521
Cell proliferation 2024 Jan;57(1):e13521
Carp scales derived double cross-linking hydrogels achieve collagen peptides sustained-released for bone regeneration.
Zheng F, Ju M, Lü Y, Hua Y, Yao W, Wu H, Zhao M, Han S, Wei Y, Liu R
International journal of biological macromolecules 2024 Jan;255:128276
International journal of biological macromolecules 2024 Jan;255:128276
Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid.
Wu K, Liu Y, Xia J, Liu J, Wang K, Liang H, Xu F, Liu D, Nie D, Tang X, Huang A, Chen C, Tang N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2304408
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2304408
Engineered extracellular vesicle-delivered TGF-β inhibitor for attenuating osteoarthritis by targeting subchondral bone.
Jing Z, Zhang G, Cai Y, Liang J, Lv L, Dang X
Journal of tissue engineering 2024 Jan-Dec;15:20417314241257781
Journal of tissue engineering 2024 Jan-Dec;15:20417314241257781
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Fan S, Tan Y, Yuan X, Liu C, Wu X, Dai T, Ni S, Wang J, Weng Y, Zhao H
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
Liu H, Pan W, Liu H, Xie D, Liao L
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Meng M, Wang J, Wang C, Zhao J, Wang H, Zhang Y, Sun H, Liu M
Calcified tissue international 2024 Feb;114(2):182-199
Calcified tissue international 2024 Feb;114(2):182-199
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Yuan Y, Xu Y, Mao Y, Liu H, Ou M, Lin Z, Zhao R, Long H, Cheng L, Sun B, Zhao S, Zeng M, Lu B, Lu H, Zhu Y, Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Inhibition of valve mesenchymal stromal cell calcium deposition by bFGF through alternative polyadenylation regulation of the CAT gene.
Zhang J, Wu J, Gao Y, Fan X, Liu X, Zhang G, Tang Y, Han L
BMC cardiovascular disorders 2024 Feb 28;24(1):128
BMC cardiovascular disorders 2024 Feb 28;24(1):128
Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2.
Li Y, Jie W, Qi Y, Mo M, Lian Y, Yin L, Huang H
iScience 2024 Feb 16;27(2):108766
iScience 2024 Feb 16;27(2):108766
PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis.
Li T, Yuan J, Xu P, Jia J, Zhao J, Zhang J, Ding R, Zhao X, He D, Wu T, Cheng X
Aging 2024 Feb 16;16(4):3694-3715
Aging 2024 Feb 16;16(4):3694-3715
Scaffold loaded LPS-hUCMSC-sEVs promote Osteo/odontogenic differentiation and angiogenic potential of hDPSCs.
Zeng J, Deng H, Li Q, Kang J, Wu Y
Tissue & cell 2024 Dec;91:102549
Tissue & cell 2024 Dec;91:102549
NIR Laser Irradiation Promotes Osteogenic Differentiation of PDLSCs Through the Activation of TRPV1 Channels and Subsequent Calcium Signaling.
Zeng JH, Ma B, Shen XQ, Geng YM
Photobiomodulation, photomedicine, and laser surgery 2024 Dec;42(12):747-753
Photobiomodulation, photomedicine, and laser surgery 2024 Dec;42(12):747-753
Foxk1 promotes bone formation through inducing aerobic glycolysis.
Liu C, Feng N, Wang Z, Zheng K, Xie Y, Wang H, Long H, Peng S
Cell death and differentiation 2024 Dec;31(12):1650-1663
Cell death and differentiation 2024 Dec;31(12):1650-1663
LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts.
Lv D, Li B, Liu Z, Zhang Q, Cao S, Xu Y, Zhang Z
Molecular medicine reports 2024 Dec;30(6)
Molecular medicine reports 2024 Dec;30(6)
Osteoinductivity enhancement by tailoring the surface chemical bond status: A strategy to mobilize host bone growth factors for in situ bone regeneration.
Li R, Zhang K, Dong C, Wang K, Gu X, Qin Y
Materials today. Bio 2024 Dec;29:101256
Materials today. Bio 2024 Dec;29:101256
Honeycomb Bionic Graphene Oxide Quantum Dot/Layered Double Hydroxide Composite Nanocoating Promotes Osteoporotic Bone Regeneration via Activating Mitophagy.
Li D, Dai D, Wang J, Zhang C
Small (Weinheim an der Bergstrasse, Germany) 2024 Dec;20(50):e2403907
Small (Weinheim an der Bergstrasse, Germany) 2024 Dec;20(50):e2403907
Single-cell RNA transcriptomics reveals Du-Zhong-Wan promotes osteoporotic fracture healing via YAP/β-catenin/VEGF axis in BMSCs.
Dong R, Wei J, Tian S, Wang J, Ma Y, Li Y, Liu RX, Liu YQ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155572
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155572
Magnesium-Based Composite Calcium Phosphate Cement Promotes Osteogenesis and Angiogenesis for Minipig Vertebral Defect Regeneration.
Tian F, Zhao Y, Wang Y, Xu H, Liu Y, Liu R, Li H, Ning R, Wang C, Gao X, Luo R, Jia S, Zhu L, Hao D
ACS biomaterials science & engineering 2024 Dec 9;10(12):7577-7593
ACS biomaterials science & engineering 2024 Dec 9;10(12):7577-7593
Acetyl-11-keto-β-boswellia acid attenuates Ti particle-induced osteoblastic oxidative stress and osteolysis through the Foxo3 signaling pathway.
Gu Y, Wu Z, Xie H, Qian Z, Li Z, Tang Y, Wang Q, Fang T, Tao H, Chen K, Zhu P, Ding Y, Xu Y, Peng Y, Ye H, Guo X, Tao Y, Gu Y
International immunopharmacology 2024 Dec 25;143(Pt 3):113547
International immunopharmacology 2024 Dec 25;143(Pt 3):113547
Icariin suppresses osteogenic differentiation and promotes bone regeneration in Porphyromonas gingivalis-infected conditions through EphA2-RhoA signaling pathway.
Wang W, Sun DF, Dong Z, Zhang WL
International immunopharmacology 2024 Dec 25;143(Pt 1):113302
International immunopharmacology 2024 Dec 25;143(Pt 1):113302
Integrative bioinformatics and experimental analysis of curcumin's role in regulating ferroptosis to combat osteoporosis.
Chen S, Pan Y, Guo Y, Sun X, Bai X, Liu M, Wang L, Xiao J, Chen C, Ma Y
Biochemical and biophysical research communications 2024 Dec 20;739:150949
Biochemical and biophysical research communications 2024 Dec 20;739:150949
Controllable All-in-One Biomimetic Hollow Nanoscaffold Initiating Pyroptosis-Mediated Antiosteosarcoma Targeted Therapy and Bone Defect Repair.
Ma Q, Xu S, Wang Q, Que Y, He P, Yang R, Wang H, Wu Z, Xiao L, Yuan X, Li X, Xu T, Hu Y
ACS applied materials & interfaces 2024 Dec 11;16(49):67424-67443
ACS applied materials & interfaces 2024 Dec 11;16(49):67424-67443
Vaspin facilitates the proliferation and osteogenic differentiation of periodontal ligament stem cells.
Jing Z, Feng X, Li X, Zhang X, Pan C
Journal of periodontal research 2024 Aug;59(4):812-820
Journal of periodontal research 2024 Aug;59(4):812-820
SCD2 Regulation Targeted by miR-200c-3p on Lipogenesis Alleviates Mesenchymal Stromal Cell Senescence.
Yu X, Zhang C, Ma Q, Gao X, Sun H, Sun Y, Wang Y, Zhang H, Shi Y, Meng X, He X
International journal of molecular sciences 2024 Aug 5;25(15)
International journal of molecular sciences 2024 Aug 5;25(15)
USP36 regulates the proliferation, survival, and differentiation of hFOB1.19 osteoblast.
Yan J, Gu X, Gao X, Shao Y, Ji M
Journal of orthopaedic surgery and research 2024 Aug 17;19(1):483
Journal of orthopaedic surgery and research 2024 Aug 17;19(1):483
A parathyroid hormone related supramolecular peptide for multi-functionalized osteoregeneration.
Hao Z, Feng Q, Wang Y, Wang Y, Li H, Hu Y, Chen T, Wang J, Chen R, Lv X, Yang Z, Chen J, Guo X, Li J
Bioactive materials 2024 Apr;34:181-203
Bioactive materials 2024 Apr;34:181-203
Longitudinal skeletal growth and growth plate morphological characteristics of chondro-tissue specific CUL7 knockout mice.
Zhang Y, Hu F, Li H, Duan Q, Pi Y, Li Y, Zhang H
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2024 Apr;253:152224
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2024 Apr;253:152224
Improving osseointegration and antimicrobial properties of titanium implants with black phosphorus nanosheets-hydroxyapatite composite coatings for vascularized bone regeneration.
Ma S, Sun R, Wang Y, Wei Y, Xu H, Liu X, Liang Z, Zhao L, Hu Y, Lian X, Guo M, Huang D
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Apr;112(4):e35403
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Apr;112(4):e35403
SGMS1 facilitates osteogenic differentiation of MSCs and strengthens osteogenesis-angiogenesis coupling by modulating Cer/PP2A/Akt pathway.
Yang K, Luan YY, Wang S, Yan YS, Wang YP, Wu J, Sun YQ, Zhang J, Chen WQ, Xiang YL, Li ZL, Zhang DL, Yin CH
iScience 2024 Apr 19;27(4):109358
iScience 2024 Apr 19;27(4):109358
Tailored apoptotic vesicles promote bone regeneration by releasing the osteoinductive brake.
Cheng Y, Zhu Y, Liu Y, Liu X, Ding Y, Li D, Zhang X, Liu Y
International journal of oral science 2024 Apr 16;16(1):31
International journal of oral science 2024 Apr 16;16(1):31
Fructose Potentiates Bone Loss and Marrow Adipose Tissue Accumulation by Inhibiting Adenosine 5'-Monophosphate-Activated Protein Kinase in Mesenchymal Stem Cells.
Yan Z, Du J, Zhao R, Liu X, Xu J, Guo L, Liu Y
Stem cells (Dayton, Ohio) 2024 Apr 15;42(4):374-384
Stem cells (Dayton, Ohio) 2024 Apr 15;42(4):374-384
Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal.
Kou Y, Rong X, Tang R, Zhang Y, Yang P, Liu H, Ma W, Li M
Frontiers in pharmacology 2023;14:1067085
Frontiers in pharmacology 2023;14:1067085
Extracellular vesicles secreted by human gingival mesenchymal stem cells promote bone regeneration in rat femoral bone defects.
Wang S, Liu Z, Yang S, Huo N, Qiao B, Zhang T, Xu J, Shi Q
Frontiers in bioengineering and biotechnology 2023;11:1098172
Frontiers in bioengineering and biotechnology 2023;11:1098172
Hypoxia-inducible factor activation promotes osteogenic transition of valve interstitial cells and accelerates aortic valve calcification in a mice model of chronic kidney disease.
Csiki DM, Ababneh H, Tóth A, Lente G, Szöőr Á, Tóth A, Fillér C, Juhász T, Nagy B Jr, Balogh E, Jeney V
Frontiers in cardiovascular medicine 2023;10:1168339
Frontiers in cardiovascular medicine 2023;10:1168339
Single-cell transcriptomic analysis identifies a highly replicating Cd168(+) skeletal stem/progenitor cell population in mouse long bones.
Hao RC, Li ZL, Wang FY, Tang J, Li PL, Yin BF, Li XT, Han MY, Mao N, Liu B, Ding L, Zhu H
Journal of genetics and genomics = Yi chuan xue bao 2023 Sep;50(9):702-712
Journal of genetics and genomics = Yi chuan xue bao 2023 Sep;50(9):702-712
Effect of sulfonation time on physicochemical, osteogenic, antibacterial properties and biocompatibility of carbon fiber reinforced polyether ether ketone.
Su J, Wu Q, Xing X, Li D, Ou Y, He K, Lin H, Qiu Y, Rausch-Fan X, Chen J
Journal of the mechanical behavior of biomedical materials 2023 Sep;145:105979
Journal of the mechanical behavior of biomedical materials 2023 Sep;145:105979
Thioredoxin-1 promotes the restoration of alveolar bone in periodontitis with diabetes.
Wu J, Huang Y, Zhan C, Chen L, Lin Z, Song Z
iScience 2023 Sep 15;26(9):107618
iScience 2023 Sep 15;26(9):107618
lncRNA MEG3 Promotes Osteogenic Differentiation of Tendon Stem Cells Via the miR-129-5p/TCF4/β-Catenin Axis and thus Contributes to Trauma-Induced Heterotopic Ossification.
Liu H, Sun Z, Luo G, Hu Y, Ruan H, Tu B, Li J, Fan C
Stem cell reviews and reports 2023 Oct;19(7):2311-2328
Stem cell reviews and reports 2023 Oct;19(7):2311-2328
PTP1B knockdown alleviates BMSCs senescence via activating AMPK-mediated mitophagy and promotes osteogenesis in senile osteoporosis.
Yang Q, Zou Y, Wei X, Ye P, Wu Y, Ai H, Zhang Z, Tan J, Zhou J, Yang Y, Dai Q, Dou C, Luo F
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166795
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166795
Icariin promotes osteogenic differentiation through the mmu_circ_0000349/mmu-miR-138-5p/Jumonji domain-containing protein-3 axis.
Ai L, Chen L, Tao Y, Wang H, Yi W
Heliyon 2023 Nov;9(11):e21885
Heliyon 2023 Nov;9(11):e21885
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Yuan Z, Li J, Zou X, Liu C, Lu J, Ni C, Tang L, Wu X, Yan F
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
5-(3',4'-dihydroxyphenyl)-γ-valerolactone, a microbiota metabolite of flavan-3-ols, activates SIRT1-mediated autophagy to attenuate H₂O₂-induced inhibition of osteoblast differentiation in MC3T3-E1 cells.
Chen F, Zhang X, Chen S, Wu Y, Wei Q, Chu X, Zhang Z
Free radical biology & medicine 2023 Nov 1;208:309-318
Free radical biology & medicine 2023 Nov 1;208:309-318
STING contributes to trauma-induced heterotopic ossification through NLRP3-dependent macrophage pyroptosis.
Sun Z, Liu H, Hu Y, Luo G, Yuan Z, Tu B, Ruan H, Li J, Fan C
Clinical immunology (Orlando, Fla.) 2023 May;250:109300
Clinical immunology (Orlando, Fla.) 2023 May;250:109300
LncRNA H19 mediates BMP9-induced angiogenesis in mesenchymal stem cells by promoting the p53-Notch1 angiogenic signaling axis.
Du C, Cheng Q, Zhao P, Wang C, Zhu Z, Wu X, Gao S, Chen B, Zou J, Huang W, Liao J
Genes & diseases 2023 May;10(3):1040-1054
Genes & diseases 2023 May;10(3):1040-1054
KLF9 Promotes Osteogenic Differentiation of Dental Stem Cells by Negatively Regulating Notch1 Mediated Signaling Pathway.
Zhao X, Mai Z, Lu Y, Cui L, Yu J
Frontiers in bioscience (Landmark edition) 2023 May 6;28(5):85
Frontiers in bioscience (Landmark edition) 2023 May 6;28(5):85
BMAL1 Promotes Valvular Interstitial Cells' Osteogenic Differentiation through NF-κ B/AKT/MAPK Pathway.
Jiang Y, Wang S, Lin W, Gu J, Li G, Shao Y
Journal of cardiovascular development and disease 2023 Mar 6;10(3)
Journal of cardiovascular development and disease 2023 Mar 6;10(3)
Saturated fatty acid promotes calcification via suppressing SIRT6 expression in vascular smooth muscle cells.
Tao Y, Wu Y, Jiang C, Wang Q, Geng X, Chen L, Zhou S, Wang X, Han M, Du D, Ding B, Li X
Journal of hypertension 2023 Mar 1;41(3):393-401
Journal of hypertension 2023 Mar 1;41(3):393-401
Tanshinone I alleviates steroid-induced osteonecrosis of femoral heads and promotes angiogenesis: in vivo and in vitro studies.
Sun K, Xue Y, Zhang X, Li X, Zhao J, Xu X, Zhang X, Yang F
Journal of orthopaedic surgery and research 2023 Jun 30;18(1):474
Journal of orthopaedic surgery and research 2023 Jun 30;18(1):474
Activation of Piezo1 promotes osteogenic differentiation of aortic valve interstitial cell through YAP-dependent glutaminolysis.
Zhong G, Su S, Li J, Zhao H, Hu D, Chen J, Li S, Lin Y, Wen L, Lin X, Xian G, Xu D, Zeng Q
Science advances 2023 Jun 2;9(22):eadg0478
Science advances 2023 Jun 2;9(22):eadg0478
Circulating miR-107 as a diagnostic biomarker of osteoporotic vertebral compression fracture increases bone formation in vitro and in vivo.
Zheng ZZ, Xu JH, Dai Y, Jiang B, Tu ZM, Li L, Li Y, Wang B
Life sciences 2023 Jun 15;323:121693
Life sciences 2023 Jun 15;323:121693
Withaferin A inhibits breast cancer-induced osteoclast differentiation.
Hahm ER, Kim SH, Singh SV
Molecular carcinogenesis 2023 Jul;62(7):1051-1061
Molecular carcinogenesis 2023 Jul;62(7):1051-1061
3D Printed Biomimetic Metamaterials with Graded Porosity and Tapering Topology for Improved Cell Seeding and Bone Regeneration.
Zhang L, Wang B, Song B, Yao Y, Choi SK, Yang C, Shi Y
Bioactive materials 2023 Jul;25:677-688
Bioactive materials 2023 Jul;25:677-688
Accelerated Bone Reconstruction by the Yoda1 Bilayer Membrane via Promotion of Osteointegration and Angiogenesis.
Yang J, Yuan K, Zhang T, Zhou S, Li W, Chen Z, Wang Y
Advanced healthcare materials 2023 Jul;12(18):e2203105
Advanced healthcare materials 2023 Jul;12(18):e2203105
Exosomes promote hFOB1.19 proliferation and differentiation via LINC00520.
Wu J, Zhang L, Liu H, Zhang J, Tang P
Journal of orthopaedic surgery and research 2023 Jul 29;18(1):546
Journal of orthopaedic surgery and research 2023 Jul 29;18(1):546
Dysfunction of Caveolae-Mediated Endocytic TβRI Degradation Results in Hypersensitivity of TGF-β/Smad Signaling in Osteogenesis Imperfecta.
Shi C, Sun B, Wu H, Zhang R, Wu L, Guo L, Li C, Xi Y, Yuan W, Zhang Y, Xu G
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2023 Jan;38(1):103-118
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2023 Jan;38(1):103-118
Calcium Phosphate Bone Cements Incorporated with Black Phosphorus Nanosheets Enhanced Osteogenesis.
Ma S, Wei Y, Sun R, Xu H, Liu X, Wang Y, Liang Z, Hu Y, Lian X, Ma X, Huang D
ACS biomaterials science & engineering 2023 Jan 9;9(1):292-302
ACS biomaterials science & engineering 2023 Jan 9;9(1):292-302
Cannabidiol Rescues TNF-α-Inhibited Proliferation, Migration, and Osteogenic/Odontogenic Differentiation of Dental Pulp Stem Cells.
Yu L, Zeng L, Zhang Z, Zhu G, Xu Z, Xia J, Weng J, Li J, Pathak JL
Biomolecules 2023 Jan 6;13(1)
Biomolecules 2023 Jan 6;13(1)
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Shi X, Wu Y, Ni H, Li M, Qi B, Xu Y
International immunopharmacology 2023 Feb;115:109600
International immunopharmacology 2023 Feb;115:109600
Atf7ip Inhibits Osteoblast Differentiation via Negative Regulation of the Sp7 Transcription Factor.
Hu G, Shi X, Qu X, Han C, Hu A, Jia Z, Yang J, Liu H, Wu Y
International journal of molecular sciences 2023 Feb 21;24(5)
International journal of molecular sciences 2023 Feb 21;24(5)
Electrospun sandwich mesh structures loaded with naringenin and vitamin K(2) polycaprolactone/gelatin nanofibers synergistically promote bone regeneration.
Wang J, Shao L, Wu X, Liu C, Ni S, Dai T, Liu H, Zhao H
Materials today. Bio 2023 Dec;23:100794
Materials today. Bio 2023 Dec;23:100794
The pterostilbene-dihydropyrazole derivative Ptd-1 ameliorates vascular calcification by regulating inflammation.
Wei X, Shen Z, Zhu M, Fang M, Wang S, Zhang T, Zhang B, Yang X, Lv Z, Duan Y, Jiang M, Ma C, Li Q, Chen Y
International immunopharmacology 2023 Dec;125(Pt B):111198
International immunopharmacology 2023 Dec;125(Pt B):111198
Nodakenin alleviates ovariectomy-induced osteoporosis by modulating osteoblastogenesis and osteoclastogenesis.
Liu C, Zhao M, Chen J, Xu L, Wang K, Li G
European journal of pharmacology 2023 Dec 5;960:176121
European journal of pharmacology 2023 Dec 5;960:176121
The Synergistic Effect of Zuogui Pill and Eldecalcitol on Improving Bone Mass and Osteogenesis in Type 2 Diabetic Osteoporosis.
Shi T, Liu T, Kou Y, Rong X, Meng L, Cui Y, Gao R, Hu S, Li M
Medicina (Kaunas, Lithuania) 2023 Aug 3;59(8)
Medicina (Kaunas, Lithuania) 2023 Aug 3;59(8)
LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs.
Jiang W, Chen Y, Sun M, Huang X, Zhang H, Fu Z, Wang J, Zhang S, Lian C, Tang B, Xiang D, Wang Y, Zhang Y, Jian C, Yang C, Zhang J, Zhang D, Chen T, Zhang J
Cell reports 2023 Aug 29;42(8):112969
Cell reports 2023 Aug 29;42(8):112969
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
Zou X, Liu C, Wu X, Yuan Z, Yan F
Journal of periodontal research 2023 Apr;58(2):444-455
Journal of periodontal research 2023 Apr;58(2):444-455
A bioactive glass functional hydrogel enhances bone augmentation via synergistic angiogenesis, self-swelling and osteogenesis.
Zhao F, Yang Z, Xiong H, Yan Y, Chen X, Shao L
Bioactive materials 2023 Apr;22:201-210
Bioactive materials 2023 Apr;22:201-210
Human urine-derived stem cell exosomes delivered via injectable GelMA templated hydrogel accelerate bone regeneration.
Lu W, Zeng M, Liu W, Ma T, Fan X, Li H, Wang Y, Wang H, Hu Y, Xie J
Materials today. Bio 2023 Apr;19:100569
Materials today. Bio 2023 Apr;19:100569
Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis.
Yu C, Yang W, Yang L, Ye L, Sun R, Gu T, Ying X, Wang M, Tang R, Fan S, Yao S
ACS applied materials & interfaces 2023 Apr 26;15(16):19976-19988
ACS applied materials & interfaces 2023 Apr 26;15(16):19976-19988
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
Cai W, Sun B, Song C, Liu F, Wu Z, Liu Z
BMC complementary medicine and therapies 2023 Apr 14;23(1):121
BMC complementary medicine and therapies 2023 Apr 14;23(1):121
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Shi L, Li Y, Shi M, Li X, Li G, Cen J, Liu D, Wei C, Lin Y
Oxidative medicine and cellular longevity 2022;2022:5142381
Oxidative medicine and cellular longevity 2022;2022:5142381
Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.
Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
BioMed research international 2022;2022:4072975
BioMed research international 2022;2022:4072975
DNA Polymerase Gamma Recovers Mitochondrial Function and Inhibits Vascular Calcification by Interacted with p53.
Wang P, Wu B, You S, Lu S, Xiong S, Zou Y, Jia P, Guo X, Zhang Y, Cao L, Sun Y, Zhang N
International journal of biological sciences 2022;18(1):409-425
International journal of biological sciences 2022;18(1):409-425
Sinomenine Inhibits Orthodontic Tooth Movement and Root Resorption in Rats and Enhances Osteogenic Differentiation of PDLSCs.
Li H, Li Y, Zou J, Yang Y, Han R, Zhang J
Drug design, development and therapy 2022;16:2949-2965
Drug design, development and therapy 2022;16:2949-2965
Identification of Polysaccharides From Dipsacus asperoides and Their Effects on Osteoblast Proliferation and Differentiation in a High-Glucose Environment.
Xu D, Liu J, Zheng W, Gao Q, Gao Y, Leng X
Frontiers in pharmacology 2022;13:851956
Frontiers in pharmacology 2022;13:851956
Quercetin Attenuates Osteoporosis in Orchiectomy Mice by Regulating Glucose and Lipid Metabolism via the GPRC6A/AMPK/mTOR Signaling Pathway.
Sun J, Pan Y, Li X, Wang L, Liu M, Tu P, Wu C, Xiao J, Han Q, Da W, Ma Y, Guo Y
Frontiers in endocrinology 2022;13:849544
Frontiers in endocrinology 2022;13:849544
The mechanosensitive Piezo1 channels contribute to the arterial medial calcification.
Szabó L, Balogh N, Tóth A, Angyal Á, Gönczi M, Csiki DM, Tóth C, Balatoni I, Jeney V, Csernoch L, Dienes B
Frontiers in physiology 2022;13:1037230
Frontiers in physiology 2022;13:1037230
Effect of condylar chondrocyte exosomes on condylar cartilage osteogenesis in rats under tensile stress.
Shi Y, Shao J, Zhang Z, Zhang J, Lu H
Frontiers in bioengineering and biotechnology 2022;10:1061855
Frontiers in bioengineering and biotechnology 2022;10:1061855
Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.
Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
Frontiers in bioengineering and biotechnology 2022;10:1028278
Frontiers in bioengineering and biotechnology 2022;10:1028278
Downregulation of miR-30b-5p Facilitates Chondrocyte Hypertrophy and Apoptosis via Targeting Runx2 in Steroid-Induced Osteonecrosis of the Femoral Head.
Lin L, Yu Y, Liu K, Jiang Y, Zhou Z
International journal of molecular sciences 2022 Sep 24;23(19)
International journal of molecular sciences 2022 Sep 24;23(19)
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
Cai J, Liu J, Yan J, Lu X, Wang X, Li S, Mustafa K, Wang H, Xue Y, Mustafa M, Kantarci A, Xing Z
Journal of periodontal research 2022 Oct;57(5):1034-1042
Journal of periodontal research 2022 Oct;57(5):1034-1042
Hesperetin, a Promising Dietary Supplement for Preventing the Development of Calcific Aortic Valve Disease.
Zhao H, Xian G, Zeng J, Zhong G, An D, Peng Y, Hu D, Lin Y, Li J, Su S, Ning Y, Xu D, Zeng Q
Antioxidants (Basel, Switzerland) 2022 Oct 24;11(11)
Antioxidants (Basel, Switzerland) 2022 Oct 24;11(11)
Selenium-sensitive histone deacetylase 2 is required for forkhead box O3A and regulates extracellular matrix metabolism in cartilage.
Zhao Y, Guo Y, Sun M, Hussion S, Zheng Y, Huang H, Huo X, Zhao Y, Zhang F, Han Y, Ning Q, Xu P, Sun J, Lu S
Journal of bone and mineral metabolism 2022 Nov;40(6):914-926
Journal of bone and mineral metabolism 2022 Nov;40(6):914-926
Knockdown of circHIPK3 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells through activating the autophagy flux.
Zhuang Z, Jin C, Li X, Han Y, Yang Q, Huang Y, Zheng Y, Li W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22590
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22590
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
Xu P, Chang J, Ma G, Liao F, Xu T, Wu Y, Yin Z
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
Effects of runt-related transcription factor 2 (RUNX2) on the autophagy of rapamycin-treated osteoblasts.
Ren C, Xu Y, Liu H, Wang Z, Ma T, Li Z, Sun L, Huang Q, Zhang K, Zhang C, Cui Y, Wang Q, Lu Y
Bioengineered 2022 Mar;13(3):5262-5276
Bioengineered 2022 Mar;13(3):5262-5276
Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes.
Gautheron J, Lima L, Akinci B, Zammouri J, Auclair M, Ucar SK, Ozen S, Altay C, Bax BE, Nemazanyy I, Lenoir V, Prip-Buus C, Acquaviva-Bourdain C, Lascols O, Fève B, Vigouroux C, Noel E, Jéru I
BMC medicine 2022 Mar 28;20(1):95
BMC medicine 2022 Mar 28;20(1):95
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
Su P, Tian Y, Yin C, Wang X, Li D, Yang C, Pei J, Deng X, King S, Li Y, Qian A
Bone 2022 Jan;154:116238
Bone 2022 Jan;154:116238
Sustained release of naringin from silk-fibroin-nanohydroxyapatite scaffold for the enhancement of bone regeneration.
Zhao ZH, Ma XL, Ma JX, Kang JY, Zhang Y, Guo Y
Materials today. Bio 2022 Jan;13:100206
Materials today. Bio 2022 Jan;13:100206
SPARC-related modular calcium binding 1 regulates aortic valve calcification by disrupting BMPR-II/p-p38 signalling.
Wang Y, Gu J, Du A, Zhang S, Deng M, Zhao R, Lu Y, Ji Y, Shao Y, Sun W, Kong X
Cardiovascular research 2022 Feb 21;118(3):913-928
Cardiovascular research 2022 Feb 21;118(3):913-928
A periodontal tissue regeneration strategy via biphasic release of zeolitic imidazolate framework-8 and FK506 using a uniaxial electrospun Janus nanofiber.
Sun M, Liu Y, Jiao K, Jia W, Jiang K, Cheng Z, Liu G, Luo Y
Journal of materials chemistry. B 2022 Feb 2;10(5):765-778
Journal of materials chemistry. B 2022 Feb 2;10(5):765-778
Ubiquitin-specific protease 47 is associated with vascular calcification in chronic kidney disease by regulating osteogenic transdifferentiation of vascular smooth muscle cells.
Xiao Q, Tang Y, Xia J, Luo H, Yu M, Chen S, Wang W, Pu L, Wang L, Li G, Li Y
Renal failure 2022 Dec;44(1):752-766
Renal failure 2022 Dec;44(1):752-766
A silk fibroin/chitosan/nanohydroxyapatite biomimetic bone scaffold combined with autologous concentrated growth factor promotes the proliferation and osteogenic differentiation of BMSCs and repair of critical bone defects.
Zhou Y, Liu X, She H, Wang R, Bai F, Xiang B
Regenerative therapy 2022 Dec;21:307-321
Regenerative therapy 2022 Dec;21:307-321
Nanosilica-Anchored Polycaprolactone/Chitosan Nanofibrous Bioscaffold to Boost Osteogenesis for Bone Tissue Engineering.
Ge S, Zhu X, Zhang C, Jia D, Shang W, Ding C, Yang J, Feng Y
Molecules (Basel, Switzerland) 2022 Dec 13;27(24)
Molecules (Basel, Switzerland) 2022 Dec 13;27(24)
Downregulating MFN2 Promotes the Differentiation of Induced Pluripotent Stem Cells into Mesenchymal Stem Cells through the PI3K/Akt/GSK-3β/Wnt Signaling Pathway.
Deng L, Yi S, Yin X, Li Y, Luan Q
Stem cells and development 2022 Apr;31(7-8):181-194
Stem cells and development 2022 Apr;31(7-8):181-194
MFN2 knockdown promotes osteogenic differentiation of iPSC-MSCs through aerobic glycolysis mediated by the Wnt/β-catenin signaling pathway.
Deng L, Yi S, Yin X, Li Y, Luan Q
Stem cell research & therapy 2022 Apr 12;13(1):162
Stem cell research & therapy 2022 Apr 12;13(1):162
Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.
Xu Y, Xin R, Sun H, Long D, Li Z, Liao H, Xue T, Zhang Z, Kang Y, Mao G
Frontiers in cell and developmental biology 2021;9:723759
Frontiers in cell and developmental biology 2021;9:723759
LINC00370 modulates miR-222-3p-RGS4 axis to protect against osteoporosis progression.
Li L, Zheng B, Zhang F, Luo X, Li F, Xu T, Zhao H, Shi G, Guo Y, Shi J, Sun J
Archives of gerontology and geriatrics 2021 Nov-Dec;97:104505
Archives of gerontology and geriatrics 2021 Nov-Dec;97:104505
Total glycosides from Eucommia ulmoides seed promoted osteogenic differentiation of adipose-derived mesenchymal stem cells and bone formation in ovariectomized rats through regulating Notch signaling pathway.
Zhou YH, Xie Q
Journal of orthopaedic surgery and research 2021 Nov 6;16(1):660
Journal of orthopaedic surgery and research 2021 Nov 6;16(1):660
miR-142a-5p promoted osteoblast differentiation via targeting nuclear factor IA.
Yuan H, Li M, Feng X, Zhu E, Wang B
Journal of cellular physiology 2021 Mar;236(3):1810-1821
Journal of cellular physiology 2021 Mar;236(3):1810-1821
Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization.
Éva Sikura K, Combi Z, Potor L, Szerafin T, Hendrik Z, Méhes G, Gergely P, Whiteman M, Beke L, Fürtös I, Balla G, Balla J
Journal of advanced research 2021 Jan;27:165-176
Journal of advanced research 2021 Jan;27:165-176
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
Journal of inorganic biochemistry 2021 Jan;214:111269
Journal of inorganic biochemistry 2021 Jan;214:111269
A polydopamine-assisted strontium-substituted apatite coating for titanium promotes osteogenesis and angiogenesis via FAK/MAPK and PI3K/AKT signaling pathways.
Sun Y, Li Y, Zhang Y, Wang T, Lin K, Liu J
Materials science & engineering. C, Materials for biological applications 2021 Dec;131:112482
Materials science & engineering. C, Materials for biological applications 2021 Dec;131:112482
The effects of Omarigliptin on promoting osteoblastic differentiation.
Liao F, Hu X, Chen R
Bioengineered 2021 Dec;12(2):11837-11846
Bioengineered 2021 Dec;12(2):11837-11846
The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway.
Zhang G, Liu W, Wang R, Zhang Y, Chen L, Chen A, Luo H, Zhong H, Shao L
International journal of nanomedicine 2020;15:2419-2435
International journal of nanomedicine 2020;15:2419-2435
The p53/miR-145a Axis Promotes Cellular Senescence and Inhibits Osteogenic Differentiation by Targeting Cbfb in Mesenchymal Stem Cells.
Xia C, Jiang T, Wang Y, Chen X, Hu Y, Gao Y
Frontiers in endocrinology 2020;11:609186
Frontiers in endocrinology 2020;11:609186
Rosamultin Attenuates Acute Hypobaric Hypoxia-Induced Bone Injuries by Regulation of Sclerostin and Its Downstream Signals.
Wang XM, Liu H, Li JY, Wei JX, Li X, Zhang YL, Li LZ, Zhang XZ
High altitude medicine & biology 2020 Sep;21(3):273-286
High altitude medicine & biology 2020 Sep;21(3):273-286
Celastrol attenuates arterial and valvular calcification via inhibiting BMP2/Smad1/5 signalling.
Su Z, Zong P, Chen J, Yang S, Shen Y, Lu Y, Yang C, Kong X, Sheng Y, Sun W
Journal of cellular and molecular medicine 2020 Nov;24(21):12476-12490
Journal of cellular and molecular medicine 2020 Nov;24(21):12476-12490
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement.
Jin Y, Ding L, Ding Z, Fu Y, Song Y, Jing Y, Li Q, Zhang J, Ni Y, Hu Q
Scientific reports 2020 Jul 9;10(1):11269
Scientific reports 2020 Jul 9;10(1):11269
VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I.
Li Q, Lu F, Chen T, Zhang K, Lu Y, Li X, Wang Y, Liu L, Tian Q, Xiong F, Chen D
International journal of oral science 2020 Jul 31;12(1):22
International journal of oral science 2020 Jul 31;12(1):22
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.
Sikura KÉ, Potor L, Szerafin T, Oros M, Nagy P, Méhes G, Hendrik Z, Zarjou A, Agarwal A, Posta N, Torregrossa R, Whiteman M, Fürtös I, Balla G, Balla J
British journal of pharmacology 2020 Feb;177(4):793-809
British journal of pharmacology 2020 Feb;177(4):793-809
Effects Of Triptolide On Tooth Movement And Root Resorption In Rats.
Yang F, Wang XX, Ma D, Cui Q, Zheng H, Liu XC, Zhang J
Drug design, development and therapy 2019;13:3963-3975
Drug design, development and therapy 2019;13:3963-3975
Enhancement of tenogenic differentiation of rat tendon-derived stem cells by biglycan.
Zhang YJ, Qing Q, Zhang YJ, Ning LJ, Cui J, Yao X, Luo JC, Ding W, Qin TW
Journal of cellular physiology 2019 Sep;234(9):15898-15910
Journal of cellular physiology 2019 Sep;234(9):15898-15910
TMEM18 inhibits osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells by inactivating β-catenin.
Zhang Y, Wang H, Yin T, Liu Y, Zhou W, Fan X, Wu L, Song C, Shao J, Yang T
Experimental cell research 2019 Oct 1;383(1):111491
Experimental cell research 2019 Oct 1;383(1):111491
ZnO nanoparticles inhibit the activity of Porphyromonas gingivalis and Actinomyces naeslundii and promote the mineralization of the cementum.
Wang J, Du L, Fu Y, Jiang P, Wang X
BMC oral health 2019 May 14;19(1):84
BMC oral health 2019 May 14;19(1):84
MicroRNA‑223 promotes osteoblast differentiation of MC3T3‑E1 cells by targeting histone deacetylase 2.
Chen J, He G, Wang Y, Cai D
International journal of molecular medicine 2019 Mar;43(3):1513-1521
International journal of molecular medicine 2019 Mar;43(3):1513-1521
Potential Role of H-Ferritin in Mitigating Valvular Mineralization.
Sikura KÉ, Potor L, Szerafin T, Zarjou A, Agarwal A, Arosio P, Poli M, Hendrik Z, Méhes G, Oros M, Posta N, Beke L, Fürtös I, Balla G, Balla J
Arteriosclerosis, thrombosis, and vascular biology 2019 Mar;39(3):413-431
Arteriosclerosis, thrombosis, and vascular biology 2019 Mar;39(3):413-431
Histone demethylase KDM7A reciprocally regulates adipogenic and osteogenic differentiation via regulation of C/EBPα and canonical Wnt signalling.
Yang X, Wang G, Wang Y, Zhou J, Yuan H, Li X, Liu Y, Wang B
Journal of cellular and molecular medicine 2019 Mar;23(3):2149-2162
Journal of cellular and molecular medicine 2019 Mar;23(3):2149-2162
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
Wang S, Xu C, Yu S, Wu X, Jie Z, Dai H
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
Hypoxia Triggers Osteochondrogenic Differentiation of Vascular Smooth Muscle Cells in an HIF-1 (Hypoxia-Inducible Factor 1)-Dependent and Reactive Oxygen Species-Dependent Manner.
Balogh E, Tóth A, Méhes G, Trencsényi G, Paragh G, Jeney V
Arteriosclerosis, thrombosis, and vascular biology 2019 Jun;39(6):1088-1099
Arteriosclerosis, thrombosis, and vascular biology 2019 Jun;39(6):1088-1099
Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification.
Gu J, Lu Y, Deng M, Qiu M, Tian Y, Ji Y, Zong P, Shao Y, Zheng R, Zhou B, Sun W, Kong X
Experimental & molecular medicine 2019 Jul 10;51(7):1-14
Experimental & molecular medicine 2019 Jul 10;51(7):1-14
LncRNA ODIR1 inhibits osteogenic differentiation of hUC-MSCs through the FBXO25/H2BK120ub/H3K4me3/OSX axis.
He S, Yang S, Zhang Y, Li X, Gao D, Zhong Y, Cao L, Ma H, Liu Y, Li G, Peng S, Shuai C
Cell death & disease 2019 Dec 11;10(12):947
Cell death & disease 2019 Dec 11;10(12):947
Inhibition of pyroptosis attenuates Staphylococcus aureus-induced bone injury in traumatic osteomyelitis.
Zhu X, Zhang K, Lu K, Shi T, Shen S, Chen X, Dong J, Gong W, Bao Z, Shi Y, Ma Y, Teng H, Jiang Q
Annals of translational medicine 2019 Apr;7(8):170
Annals of translational medicine 2019 Apr;7(8):170
The microRNA-10a/ID3/RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament.
Xu C, Zhang H, Gu W, Wu H, Chen Y, Zhou W, Sun B, Shen X, Zhang Z, Wang Y, Liu Y, Yuan W
Scientific reports 2018 Jun 15;8(1):9225
Scientific reports 2018 Jun 15;8(1):9225
Aryl Hydrocarbon Receptor Antagonists Mitigate the Effects of Dioxin on Critical Cellular Functions in Differentiating Human Osteoblast-Like Cells.
Yun C, Katchko KM, Schallmo MS, Jeong S, Yun J, Chen CH, Weiner JA, Park C, George A, Stupp SI, Hsu WK, Hsu EL
International journal of molecular sciences 2018 Jan 11;19(1)
International journal of molecular sciences 2018 Jan 11;19(1)
The effect of different hydroxyapatite microparticles on the osteogenic differentiation of MC3T3-E1 preosteoblasts.
Xu W, Xu C, Yi J, Dai H
Journal of materials chemistry. B 2018 Aug 28;6(32):5234-5242
Journal of materials chemistry. B 2018 Aug 28;6(32):5234-5242
Angiopoietin-like 2 has auxo-action in atherosclerosis by promoting atherosclerotic calcification.
Jiao L, Zhuang Y, Jiang M, Zhou JH, Wu M, Chen ZJ, Fang JH, Deng YS
International journal of clinical and experimental pathology 2017;10(8):9084-9091
International journal of clinical and experimental pathology 2017;10(8):9084-9091
APE1/Ref-1 Inhibits Phosphate-Induced Calcification and Osteoblastic Phenotype Changes in Vascular Smooth Muscle Cells.
Lee KM, Lee EO, Lee YR, Joo HK, Park MS, Kim CS, Choi S, Jeong JO, Jeon BH
International journal of molecular sciences 2017 Sep 25;18(10)
International journal of molecular sciences 2017 Sep 25;18(10)
Effect of pioglitazone on the calcification of rat vascular smooth muscle cells through the downregulation of the Wnt/β‑catenin signaling pathway.
Gao M, Chen T, Wu L, Zhao X, Mao H, Xing C
Molecular medicine reports 2017 Nov;16(5):6208-6213
Molecular medicine reports 2017 Nov;16(5):6208-6213
Graphene/single-walled carbon nanotube hybrids promoting osteogenic differentiation of mesenchymal stem cells by activating p38 signaling pathway.
Yan X, Yang W, Shao Z, Yang S, Liu X
International journal of nanomedicine 2016;11:5473-5484
International journal of nanomedicine 2016;11:5473-5484
The In Vitro and In Vivo Osteogenic Capability of the Extraction Socket-Derived Early Healing Tissue.
Luo J, Xu J, Cai J, Wang L, Sun Q, Yang P
Journal of periodontology 2016 Sep;87(9):1057-66
Journal of periodontology 2016 Sep;87(9):1057-66
Osteogenic differentiation of human lens epithelial cells might contribute to lens calcification.
Balogh E, Tóth A, Tolnai E, Bodó T, Bányai E, Szabó DJ, Petrovski G, Jeney V
Biochimica et biophysica acta 2016 Sep;1862(9):1724-31
Biochimica et biophysica acta 2016 Sep;1862(9):1724-31
Resveratrol Ameliorated Vascular Calcification by Regulating Sirt-1 and Nrf2.
Zhang P, Li Y, Du Y, Li G, Wang L, Zhou F
Transplantation proceedings 2016 Dec;48(10):3378-3386
Transplantation proceedings 2016 Dec;48(10):3378-3386
Hydrogen peroxide prevents vascular calcification induced ROS production by regulating Nrf-2 pathway.
Zhang W, Li Y, Ding H, Du Y, Wang L
Renal failure 2016 Aug;38(7):1099-106
Renal failure 2016 Aug;38(7):1099-106
The Role and Mechanism of α-Klotho in the Calcification of Rat Aortic Vascular Smooth Muscle Cells.
Chen T, Mao H, Chen C, Wu L, Wang N, Zhao X, Qian J, Xing C
BioMed research international 2015;2015:194362
BioMed research international 2015;2015:194362
Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways.
Yuan ZS, Zhou YZ, Liao XB, Luo JW, Shen KJ, Hu YR, Gu L, Li JM, Tan CM, Chen HM, Zhou XM
Amino acids 2015 Dec;47(12):2475-82
Amino acids 2015 Dec;47(12):2475-82
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- Main image
- Experimental details
- ROS1728 cells were subjected to SDS PAGE followed by western blot with 20700-1-AP( RUNX2 Antibody) at dilution of 1:600
- Other comments
- WB
