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Learn20700-1-AP
antibody from Proteintech Group
Targeting: RUNX2
AML3, CBFA1, CCD, CCD1, PEBP2A1, PEBP2aA1
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- Antibody Data
- Antigen structure
- References [133]
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- Product number
- 20700-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20700-1-AP, RRID:AB_2722783
- Product name
- RUNX2 antibody
- Antibody type
- Polyclonal
- Description
- RUNX2 antibody (Cat. #20700-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Periostin Is a Candidate Regulator of the Host Microenvironment in Regeneration of Pulp and Dentin Complex and Periodontal Ligament in Transplantation with Stem Cell-Conditioned Medium.
NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease.
METTL14-mediated methylation of SLC25A3 mitigates mitochondrial damage in osteoblasts, leading to the improvement of osteoporosis.
Identification of key pathways in zirconia/dental pulp stem cell composite scaffold-mediated macrophage polarization through transcriptome sequencing.
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
The multi-protective effect of IL-37-Smad3 against ox-LDL induced dysfunction of endothelial cells.
β-Receptor blocker enhances the anabolic effect of PTH after osteoporotic fracture.
Alpha-lipoic Acid Prevents Bone Loss in Type 2 Diabetes and Postmenopausal Osteoporosis Coexisting Conditions by Modulating the YAP/Glut4 Pathway.
High phosphate and calcium induce osteoblastic phenotype switching and calcification of corneal epithelial cells in a Runx2-dependent and synergistic manner; a possible mechanism of chronic kidney disease-associated corneal calcification.
Unraveling the mechanism in l-Caldesmon regulating the osteogenic differentiation of PDLSCs: An innovative perspective.
Effects of tetrahedral DNA nanostructures on the treatment of osteoporosis.
PM(2.5) exposure inhibits osteoblast differentiation by increasing the ubiquitination and degradation of Smad4.
Influence of METTL3 knockdown on PDLSC osteogenesis in E. coli LPS-induced inflammation.
Pectolinarigenin ameliorates osteoporosis via enhancing Wnt signaling cascade in PPARβ-dependent manner.
KLF2/PPARγ axis contributes to trauma-induced heterotopic ossification by regulating mitochondrial dysfunction.
Carp scales derived double cross-linking hydrogels achieve collagen peptides sustained-released for bone regeneration.
Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid.
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Inhibition of valve mesenchymal stromal cell calcium deposition by bFGF through alternative polyadenylation regulation of the CAT gene.
Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2.
PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis.
A parathyroid hormone related supramolecular peptide for multi-functionalized osteoregeneration.
Longitudinal skeletal growth and growth plate morphological characteristics of chondro-tissue specific CUL7 knockout mice.
Improving osseointegration and antimicrobial properties of titanium implants with black phosphorus nanosheets-hydroxyapatite composite coatings for vascularized bone regeneration.
SGMS1 facilitates osteogenic differentiation of MSCs and strengthens osteogenesis-angiogenesis coupling by modulating Cer/PP2A/Akt pathway.
Tailored apoptotic vesicles promote bone regeneration by releasing the osteoinductive brake.
Fructose Potentiates Bone Loss and Marrow Adipose Tissue Accumulation by Inhibiting Adenosine 5'-Monophosphate-Activated Protein Kinase in Mesenchymal Stem Cells.
Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal.
Extracellular vesicles secreted by human gingival mesenchymal stem cells promote bone regeneration in rat femoral bone defects.
Hypoxia-inducible factor activation promotes osteogenic transition of valve interstitial cells and accelerates aortic valve calcification in a mice model of chronic kidney disease.
Single-cell transcriptomic analysis identifies a highly replicating Cd168(+) skeletal stem/progenitor cell population in mouse long bones.
Effect of sulfonation time on physicochemical, osteogenic, antibacterial properties and biocompatibility of carbon fiber reinforced polyether ether ketone.
Thioredoxin-1 promotes the restoration of alveolar bone in periodontitis with diabetes.
lncRNA MEG3 Promotes Osteogenic Differentiation of Tendon Stem Cells Via the miR-129-5p/TCF4/β-Catenin Axis and thus Contributes to Trauma-Induced Heterotopic Ossification.
PTP1B knockdown alleviates BMSCs senescence via activating AMPK-mediated mitophagy and promotes osteogenesis in senile osteoporosis.
Icariin promotes osteogenic differentiation through the mmu_circ_0000349/mmu-miR-138-5p/Jumonji domain-containing protein-3 axis.
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
5-(3',4'-dihydroxyphenyl)-γ-valerolactone, a microbiota metabolite of flavan-3-ols, activates SIRT1-mediated autophagy to attenuate H₂O₂-induced inhibition of osteoblast differentiation in MC3T3-E1 cells.
STING contributes to trauma-induced heterotopic ossification through NLRP3-dependent macrophage pyroptosis.
LncRNA H19 mediates BMP9-induced angiogenesis in mesenchymal stem cells by promoting the p53-Notch1 angiogenic signaling axis.
KLF9 Promotes Osteogenic Differentiation of Dental Stem Cells by Negatively Regulating Notch1 Mediated Signaling Pathway.
BMAL1 Promotes Valvular Interstitial Cells' Osteogenic Differentiation through NF-κ B/AKT/MAPK Pathway.
Saturated fatty acid promotes calcification via suppressing SIRT6 expression in vascular smooth muscle cells.
Tanshinone I alleviates steroid-induced osteonecrosis of femoral heads and promotes angiogenesis: in vivo and in vitro studies.
Activation of Piezo1 promotes osteogenic differentiation of aortic valve interstitial cell through YAP-dependent glutaminolysis.
Circulating miR-107 as a diagnostic biomarker of osteoporotic vertebral compression fracture increases bone formation in vitro and in vivo.
Withaferin A inhibits breast cancer-induced osteoclast differentiation.
3D Printed Biomimetic Metamaterials with Graded Porosity and Tapering Topology for Improved Cell Seeding and Bone Regeneration.
Accelerated Bone Reconstruction by the Yoda1 Bilayer Membrane via Promotion of Osteointegration and Angiogenesis.
Exosomes promote hFOB1.19 proliferation and differentiation via LINC00520.
Dysfunction of Caveolae-Mediated Endocytic TβRI Degradation Results in Hypersensitivity of TGF-β/Smad Signaling in Osteogenesis Imperfecta.
Calcium Phosphate Bone Cements Incorporated with Black Phosphorus Nanosheets Enhanced Osteogenesis.
Cannabidiol Rescues TNF-α-Inhibited Proliferation, Migration, and Osteogenic/Odontogenic Differentiation of Dental Pulp Stem Cells.
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Atf7ip Inhibits Osteoblast Differentiation via Negative Regulation of the Sp7 Transcription Factor.
Electrospun sandwich mesh structures loaded with naringenin and vitamin K(2) polycaprolactone/gelatin nanofibers synergistically promote bone regeneration.
The pterostilbene-dihydropyrazole derivative Ptd-1 ameliorates vascular calcification by regulating inflammation.
Nodakenin alleviates ovariectomy-induced osteoporosis by modulating osteoblastogenesis and osteoclastogenesis.
The Synergistic Effect of Zuogui Pill and Eldecalcitol on Improving Bone Mass and Osteogenesis in Type 2 Diabetic Osteoporosis.
LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs.
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
A bioactive glass functional hydrogel enhances bone augmentation via synergistic angiogenesis, self-swelling and osteogenesis.
Human urine-derived stem cell exosomes delivered via injectable GelMA templated hydrogel accelerate bone regeneration.
Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis.
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.
DNA Polymerase Gamma Recovers Mitochondrial Function and Inhibits Vascular Calcification by Interacted with p53.
Sinomenine Inhibits Orthodontic Tooth Movement and Root Resorption in Rats and Enhances Osteogenic Differentiation of PDLSCs.
Identification of Polysaccharides From Dipsacus asperoides and Their Effects on Osteoblast Proliferation and Differentiation in a High-Glucose Environment.
Quercetin Attenuates Osteoporosis in Orchiectomy Mice by Regulating Glucose and Lipid Metabolism via the GPRC6A/AMPK/mTOR Signaling Pathway.
The mechanosensitive Piezo1 channels contribute to the arterial medial calcification.
Effect of condylar chondrocyte exosomes on condylar cartilage osteogenesis in rats under tensile stress.
Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.
Downregulation of miR-30b-5p Facilitates Chondrocyte Hypertrophy and Apoptosis via Targeting Runx2 in Steroid-Induced Osteonecrosis of the Femoral Head.
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
Hesperetin, a Promising Dietary Supplement for Preventing the Development of Calcific Aortic Valve Disease.
Selenium-sensitive histone deacetylase 2 is required for forkhead box O3A and regulates extracellular matrix metabolism in cartilage.
Knockdown of circHIPK3 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells through activating the autophagy flux.
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
Effects of runt-related transcription factor 2 (RUNX2) on the autophagy of rapamycin-treated osteoblasts.
Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes.
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
Sustained release of naringin from silk-fibroin-nanohydroxyapatite scaffold for the enhancement of bone regeneration.
A periodontal tissue regeneration strategy via biphasic release of zeolitic imidazolate framework-8 and FK506 using a uniaxial electrospun Janus nanofiber.
Ubiquitin-specific protease 47 is associated with vascular calcification in chronic kidney disease by regulating osteogenic transdifferentiation of vascular smooth muscle cells.
A silk fibroin/chitosan/nanohydroxyapatite biomimetic bone scaffold combined with autologous concentrated growth factor promotes the proliferation and osteogenic differentiation of BMSCs and repair of critical bone defects.
Nanosilica-Anchored Polycaprolactone/Chitosan Nanofibrous Bioscaffold to Boost Osteogenesis for Bone Tissue Engineering.
Downregulating MFN2 Promotes the Differentiation of Induced Pluripotent Stem Cells into Mesenchymal Stem Cells through the PI3K/Akt/GSK-3β/Wnt Signaling Pathway.
MFN2 knockdown promotes osteogenic differentiation of iPSC-MSCs through aerobic glycolysis mediated by the Wnt/β-catenin signaling pathway.
Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.
LINC00370 modulates miR-222-3p-RGS4 axis to protect against osteoporosis progression.
Total glycosides from Eucommia ulmoides seed promoted osteogenic differentiation of adipose-derived mesenchymal stem cells and bone formation in ovariectomized rats through regulating Notch signaling pathway.
miR-142a-5p promoted osteoblast differentiation via targeting nuclear factor IA.
Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization.
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
A polydopamine-assisted strontium-substituted apatite coating for titanium promotes osteogenesis and angiogenesis via FAK/MAPK and PI3K/AKT signaling pathways.
The effects of Omarigliptin on promoting osteoblastic differentiation.
The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway.
The p53/miR-145a Axis Promotes Cellular Senescence and Inhibits Osteogenic Differentiation by Targeting Cbfb in Mesenchymal Stem Cells.
Rosamultin Attenuates Acute Hypobaric Hypoxia-Induced Bone Injuries by Regulation of Sclerostin and Its Downstream Signals.
Celastrol attenuates arterial and valvular calcification via inhibiting BMP2/Smad1/5 signalling.
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement.
VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I.
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.
Effects Of Triptolide On Tooth Movement And Root Resorption In Rats.
Enhancement of tenogenic differentiation of rat tendon-derived stem cells by biglycan.
TMEM18 inhibits osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells by inactivating β-catenin.
ZnO nanoparticles inhibit the activity of Porphyromonas gingivalis and Actinomyces naeslundii and promote the mineralization of the cementum.
MicroRNA‑223 promotes osteoblast differentiation of MC3T3‑E1 cells by targeting histone deacetylase 2.
Potential Role of H-Ferritin in Mitigating Valvular Mineralization.
Histone demethylase KDM7A reciprocally regulates adipogenic and osteogenic differentiation via regulation of C/EBPα and canonical Wnt signalling.
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
Hypoxia Triggers Osteochondrogenic Differentiation of Vascular Smooth Muscle Cells in an HIF-1 (Hypoxia-Inducible Factor 1)-Dependent and Reactive Oxygen Species-Dependent Manner.
Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification.
LncRNA ODIR1 inhibits osteogenic differentiation of hUC-MSCs through the FBXO25/H2BK120ub/H3K4me3/OSX axis.
Inhibition of pyroptosis attenuates Staphylococcus aureus-induced bone injury in traumatic osteomyelitis.
The microRNA-10a/ID3/RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament.
Aryl Hydrocarbon Receptor Antagonists Mitigate the Effects of Dioxin on Critical Cellular Functions in Differentiating Human Osteoblast-Like Cells.
The effect of different hydroxyapatite microparticles on the osteogenic differentiation of MC3T3-E1 preosteoblasts.
APE1/Ref-1 Inhibits Phosphate-Induced Calcification and Osteoblastic Phenotype Changes in Vascular Smooth Muscle Cells.
Effect of pioglitazone on the calcification of rat vascular smooth muscle cells through the downregulation of the Wnt/β‑catenin signaling pathway.
Graphene/single-walled carbon nanotube hybrids promoting osteogenic differentiation of mesenchymal stem cells by activating p38 signaling pathway.
The In Vitro and In Vivo Osteogenic Capability of the Extraction Socket-Derived Early Healing Tissue.
Osteogenic differentiation of human lens epithelial cells might contribute to lens calcification.
Resveratrol Ameliorated Vascular Calcification by Regulating Sirt-1 and Nrf2.
Hydrogen peroxide prevents vascular calcification induced ROS production by regulating Nrf-2 pathway.
The Role and Mechanism of α-Klotho in the Calcification of Rat Aortic Vascular Smooth Muscle Cells.
Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways.
Sakatoku S, Hayashi Y, Futenma T, Sugita Y, Ishizaka R, Nawa H, Iohara K
Stem cells international 2024;2024:7685280
Stem cells international 2024;2024:7685280
NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease.
Wang H, Mao W, Zhang Y, Feng W, Bai B, Ji B, Chen J, Cheng B, Yan F
Free radical biology & medicine 2024 Sep;222:331-343
Free radical biology & medicine 2024 Sep;222:331-343
METTL14-mediated methylation of SLC25A3 mitigates mitochondrial damage in osteoblasts, leading to the improvement of osteoporosis.
Wang P, Zhou W, Chen F, Zhang X, Zhang Q, Chen Y, Zhang N
Experimental gerontology 2024 Sep;194:112496
Experimental gerontology 2024 Sep;194:112496
Identification of key pathways in zirconia/dental pulp stem cell composite scaffold-mediated macrophage polarization through transcriptome sequencing.
Liu B, He M, Chen B, Shuai Y, He X, Liu K, Li J, Jin L
Biotechnology & genetic engineering reviews 2024 Oct;40(2):833-857
Biotechnology & genetic engineering reviews 2024 Oct;40(2):833-857
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Huang L, Zhang S, Bian M, Xiang X, Xiao L, Wang J, Lu S, Chen W, Zhang C, Mo G, Jiang L, Li Y, Zhang J
Acta biomaterialia 2024 May;180:82-103
Acta biomaterialia 2024 May;180:82-103
The multi-protective effect of IL-37-Smad3 against ox-LDL induced dysfunction of endothelial cells.
Zhang C, Huang X, Xie B, Lian D, Chen J, Li W, Lin Y, Cai X, Li J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116268
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116268
β-Receptor blocker enhances the anabolic effect of PTH after osteoporotic fracture.
Huang J, Wu T, Jiang YR, Zheng XQ, Wang H, Liu H, Wang H, Leng HJ, Fan DW, Yuan WQ, Song CL
Bone research 2024 Mar 21;12(1):18
Bone research 2024 Mar 21;12(1):18
Alpha-lipoic Acid Prevents Bone Loss in Type 2 Diabetes and Postmenopausal Osteoporosis Coexisting Conditions by Modulating the YAP/Glut4 Pathway.
Xu L, Zhang C, Bao J, Han G, Wang C, Cai Y, Xu G, Sun H, Liu M
Cell biochemistry and biophysics 2024 Jun;82(2):669-685
Cell biochemistry and biophysics 2024 Jun;82(2):669-685
High phosphate and calcium induce osteoblastic phenotype switching and calcification of corneal epithelial cells in a Runx2-dependent and synergistic manner; a possible mechanism of chronic kidney disease-associated corneal calcification.
Ababneh H, Tóth A, Lente G, Balogh E, Csiki DM, Nagy B Jr, Szöőr Á, Jeney V
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167171
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167171
Unraveling the mechanism in l-Caldesmon regulating the osteogenic differentiation of PDLSCs: An innovative perspective.
Li Y, Mei Z, Deng P, Zhou S, Qian A, Zhang X, Li J
Cellular signalling 2024 Jun;118:111147
Cellular signalling 2024 Jun;118:111147
Effects of tetrahedral DNA nanostructures on the treatment of osteoporosis.
Cui W, Yang X, Dou Y, Du Y, Ma X, Hu L, Lin Y
Cell proliferation 2024 Jul;57(7):e13625
Cell proliferation 2024 Jul;57(7):e13625
PM(2.5) exposure inhibits osteoblast differentiation by increasing the ubiquitination and degradation of Smad4.
Yang J, Han C, Ye J, Hu X, Wang R, Shen J, Li L, Hu G, Shi X, Jia Z, Qu X, Liu H, Zhang X, Wu Y
Toxicology letters 2024 Jul;398:127-139
Toxicology letters 2024 Jul;398:127-139
Influence of METTL3 knockdown on PDLSC osteogenesis in E. coli LPS-induced inflammation.
Chen H, Peng L, Wang Z, He Y, Zhang X
Oral diseases 2024 Jul;30(5):3225-3238
Oral diseases 2024 Jul;30(5):3225-3238
Pectolinarigenin ameliorates osteoporosis via enhancing Wnt signaling cascade in PPARβ-dependent manner.
Qian J, Li Q, Song Y, Gong X, Hu K, Ge G, Sun Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155587
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155587
KLF2/PPARγ axis contributes to trauma-induced heterotopic ossification by regulating mitochondrial dysfunction.
Sun Z, Liu H, Hu Y, Luo G, Yuan Z, Liu W, Tu B, Ruan H, Li J, Fan C
Cell proliferation 2024 Jan;57(1):e13521
Cell proliferation 2024 Jan;57(1):e13521
Carp scales derived double cross-linking hydrogels achieve collagen peptides sustained-released for bone regeneration.
Zheng F, Ju M, Lü Y, Hua Y, Yao W, Wu H, Zhao M, Han S, Wei Y, Liu R
International journal of biological macromolecules 2024 Jan;255:128276
International journal of biological macromolecules 2024 Jan;255:128276
Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid.
Wu K, Liu Y, Xia J, Liu J, Wang K, Liang H, Xu F, Liu D, Nie D, Tang X, Huang A, Chen C, Tang N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2304408
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2304408
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Fan S, Tan Y, Yuan X, Liu C, Wu X, Dai T, Ni S, Wang J, Weng Y, Zhao H
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
Liu H, Pan W, Liu H, Xie D, Liao L
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.
Meng M, Wang J, Wang C, Zhao J, Wang H, Zhang Y, Sun H, Liu M
Calcified tissue international 2024 Feb;114(2):182-199
Calcified tissue international 2024 Feb;114(2):182-199
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Yuan Y, Xu Y, Mao Y, Liu H, Ou M, Lin Z, Zhao R, Long H, Cheng L, Sun B, Zhao S, Zeng M, Lu B, Lu H, Zhu Y, Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Inhibition of valve mesenchymal stromal cell calcium deposition by bFGF through alternative polyadenylation regulation of the CAT gene.
Zhang J, Wu J, Gao Y, Fan X, Liu X, Zhang G, Tang Y, Han L
BMC cardiovascular disorders 2024 Feb 28;24(1):128
BMC cardiovascular disorders 2024 Feb 28;24(1):128
Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2.
Li Y, Jie W, Qi Y, Mo M, Lian Y, Yin L, Huang H
iScience 2024 Feb 16;27(2):108766
iScience 2024 Feb 16;27(2):108766
PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis.
Li T, Yuan J, Xu P, Jia J, Zhao J, Zhang J, Ding R, Zhao X, He D, Wu T, Cheng X
Aging 2024 Feb 16;16(4):3694-3715
Aging 2024 Feb 16;16(4):3694-3715
A parathyroid hormone related supramolecular peptide for multi-functionalized osteoregeneration.
Hao Z, Feng Q, Wang Y, Wang Y, Li H, Hu Y, Chen T, Wang J, Chen R, Lv X, Yang Z, Chen J, Guo X, Li J
Bioactive materials 2024 Apr;34:181-203
Bioactive materials 2024 Apr;34:181-203
Longitudinal skeletal growth and growth plate morphological characteristics of chondro-tissue specific CUL7 knockout mice.
Zhang Y, Hu F, Li H, Duan Q, Pi Y, Li Y, Zhang H
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2024 Apr;253:152224
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2024 Apr;253:152224
Improving osseointegration and antimicrobial properties of titanium implants with black phosphorus nanosheets-hydroxyapatite composite coatings for vascularized bone regeneration.
Ma S, Sun R, Wang Y, Wei Y, Xu H, Liu X, Liang Z, Zhao L, Hu Y, Lian X, Guo M, Huang D
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Apr;112(4):e35403
Journal of biomedical materials research. Part B, Applied biomaterials 2024 Apr;112(4):e35403
SGMS1 facilitates osteogenic differentiation of MSCs and strengthens osteogenesis-angiogenesis coupling by modulating Cer/PP2A/Akt pathway.
Yang K, Luan YY, Wang S, Yan YS, Wang YP, Wu J, Sun YQ, Zhang J, Chen WQ, Xiang YL, Li ZL, Zhang DL, Yin CH
iScience 2024 Apr 19;27(4):109358
iScience 2024 Apr 19;27(4):109358
Tailored apoptotic vesicles promote bone regeneration by releasing the osteoinductive brake.
Cheng Y, Zhu Y, Liu Y, Liu X, Ding Y, Li D, Zhang X, Liu Y
International journal of oral science 2024 Apr 16;16(1):31
International journal of oral science 2024 Apr 16;16(1):31
Fructose Potentiates Bone Loss and Marrow Adipose Tissue Accumulation by Inhibiting Adenosine 5'-Monophosphate-Activated Protein Kinase in Mesenchymal Stem Cells.
Yan Z, Du J, Zhao R, Liu X, Xu J, Guo L, Liu Y
Stem cells (Dayton, Ohio) 2024 Apr 15;42(4):374-384
Stem cells (Dayton, Ohio) 2024 Apr 15;42(4):374-384
Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal.
Kou Y, Rong X, Tang R, Zhang Y, Yang P, Liu H, Ma W, Li M
Frontiers in pharmacology 2023;14:1067085
Frontiers in pharmacology 2023;14:1067085
Extracellular vesicles secreted by human gingival mesenchymal stem cells promote bone regeneration in rat femoral bone defects.
Wang S, Liu Z, Yang S, Huo N, Qiao B, Zhang T, Xu J, Shi Q
Frontiers in bioengineering and biotechnology 2023;11:1098172
Frontiers in bioengineering and biotechnology 2023;11:1098172
Hypoxia-inducible factor activation promotes osteogenic transition of valve interstitial cells and accelerates aortic valve calcification in a mice model of chronic kidney disease.
Csiki DM, Ababneh H, Tóth A, Lente G, Szöőr Á, Tóth A, Fillér C, Juhász T, Nagy B Jr, Balogh E, Jeney V
Frontiers in cardiovascular medicine 2023;10:1168339
Frontiers in cardiovascular medicine 2023;10:1168339
Single-cell transcriptomic analysis identifies a highly replicating Cd168(+) skeletal stem/progenitor cell population in mouse long bones.
Hao RC, Li ZL, Wang FY, Tang J, Li PL, Yin BF, Li XT, Han MY, Mao N, Liu B, Ding L, Zhu H
Journal of genetics and genomics = Yi chuan xue bao 2023 Sep;50(9):702-712
Journal of genetics and genomics = Yi chuan xue bao 2023 Sep;50(9):702-712
Effect of sulfonation time on physicochemical, osteogenic, antibacterial properties and biocompatibility of carbon fiber reinforced polyether ether ketone.
Su J, Wu Q, Xing X, Li D, Ou Y, He K, Lin H, Qiu Y, Rausch-Fan X, Chen J
Journal of the mechanical behavior of biomedical materials 2023 Sep;145:105979
Journal of the mechanical behavior of biomedical materials 2023 Sep;145:105979
Thioredoxin-1 promotes the restoration of alveolar bone in periodontitis with diabetes.
Wu J, Huang Y, Zhan C, Chen L, Lin Z, Song Z
iScience 2023 Sep 15;26(9):107618
iScience 2023 Sep 15;26(9):107618
lncRNA MEG3 Promotes Osteogenic Differentiation of Tendon Stem Cells Via the miR-129-5p/TCF4/β-Catenin Axis and thus Contributes to Trauma-Induced Heterotopic Ossification.
Liu H, Sun Z, Luo G, Hu Y, Ruan H, Tu B, Li J, Fan C
Stem cell reviews and reports 2023 Oct;19(7):2311-2328
Stem cell reviews and reports 2023 Oct;19(7):2311-2328
PTP1B knockdown alleviates BMSCs senescence via activating AMPK-mediated mitophagy and promotes osteogenesis in senile osteoporosis.
Yang Q, Zou Y, Wei X, Ye P, Wu Y, Ai H, Zhang Z, Tan J, Zhou J, Yang Y, Dai Q, Dou C, Luo F
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166795
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166795
Icariin promotes osteogenic differentiation through the mmu_circ_0000349/mmu-miR-138-5p/Jumonji domain-containing protein-3 axis.
Ai L, Chen L, Tao Y, Wang H, Yi W
Heliyon 2023 Nov;9(11):e21885
Heliyon 2023 Nov;9(11):e21885
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Yuan Z, Li J, Zou X, Liu C, Lu J, Ni C, Tang L, Wu X, Yan F
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
5-(3',4'-dihydroxyphenyl)-γ-valerolactone, a microbiota metabolite of flavan-3-ols, activates SIRT1-mediated autophagy to attenuate H₂O₂-induced inhibition of osteoblast differentiation in MC3T3-E1 cells.
Chen F, Zhang X, Chen S, Wu Y, Wei Q, Chu X, Zhang Z
Free radical biology & medicine 2023 Nov 1;208:309-318
Free radical biology & medicine 2023 Nov 1;208:309-318
STING contributes to trauma-induced heterotopic ossification through NLRP3-dependent macrophage pyroptosis.
Sun Z, Liu H, Hu Y, Luo G, Yuan Z, Tu B, Ruan H, Li J, Fan C
Clinical immunology (Orlando, Fla.) 2023 May;250:109300
Clinical immunology (Orlando, Fla.) 2023 May;250:109300
LncRNA H19 mediates BMP9-induced angiogenesis in mesenchymal stem cells by promoting the p53-Notch1 angiogenic signaling axis.
Du C, Cheng Q, Zhao P, Wang C, Zhu Z, Wu X, Gao S, Chen B, Zou J, Huang W, Liao J
Genes & diseases 2023 May;10(3):1040-1054
Genes & diseases 2023 May;10(3):1040-1054
KLF9 Promotes Osteogenic Differentiation of Dental Stem Cells by Negatively Regulating Notch1 Mediated Signaling Pathway.
Zhao X, Mai Z, Lu Y, Cui L, Yu J
Frontiers in bioscience (Landmark edition) 2023 May 6;28(5):85
Frontiers in bioscience (Landmark edition) 2023 May 6;28(5):85
BMAL1 Promotes Valvular Interstitial Cells' Osteogenic Differentiation through NF-κ B/AKT/MAPK Pathway.
Jiang Y, Wang S, Lin W, Gu J, Li G, Shao Y
Journal of cardiovascular development and disease 2023 Mar 6;10(3)
Journal of cardiovascular development and disease 2023 Mar 6;10(3)
Saturated fatty acid promotes calcification via suppressing SIRT6 expression in vascular smooth muscle cells.
Tao Y, Wu Y, Jiang C, Wang Q, Geng X, Chen L, Zhou S, Wang X, Han M, Du D, Ding B, Li X
Journal of hypertension 2023 Mar 1;41(3):393-401
Journal of hypertension 2023 Mar 1;41(3):393-401
Tanshinone I alleviates steroid-induced osteonecrosis of femoral heads and promotes angiogenesis: in vivo and in vitro studies.
Sun K, Xue Y, Zhang X, Li X, Zhao J, Xu X, Zhang X, Yang F
Journal of orthopaedic surgery and research 2023 Jun 30;18(1):474
Journal of orthopaedic surgery and research 2023 Jun 30;18(1):474
Activation of Piezo1 promotes osteogenic differentiation of aortic valve interstitial cell through YAP-dependent glutaminolysis.
Zhong G, Su S, Li J, Zhao H, Hu D, Chen J, Li S, Lin Y, Wen L, Lin X, Xian G, Xu D, Zeng Q
Science advances 2023 Jun 2;9(22):eadg0478
Science advances 2023 Jun 2;9(22):eadg0478
Circulating miR-107 as a diagnostic biomarker of osteoporotic vertebral compression fracture increases bone formation in vitro and in vivo.
Zheng ZZ, Xu JH, Dai Y, Jiang B, Tu ZM, Li L, Li Y, Wang B
Life sciences 2023 Jun 15;323:121693
Life sciences 2023 Jun 15;323:121693
Withaferin A inhibits breast cancer-induced osteoclast differentiation.
Hahm ER, Kim SH, Singh SV
Molecular carcinogenesis 2023 Jul;62(7):1051-1061
Molecular carcinogenesis 2023 Jul;62(7):1051-1061
3D Printed Biomimetic Metamaterials with Graded Porosity and Tapering Topology for Improved Cell Seeding and Bone Regeneration.
Zhang L, Wang B, Song B, Yao Y, Choi SK, Yang C, Shi Y
Bioactive materials 2023 Jul;25:677-688
Bioactive materials 2023 Jul;25:677-688
Accelerated Bone Reconstruction by the Yoda1 Bilayer Membrane via Promotion of Osteointegration and Angiogenesis.
Yang J, Yuan K, Zhang T, Zhou S, Li W, Chen Z, Wang Y
Advanced healthcare materials 2023 Jul;12(18):e2203105
Advanced healthcare materials 2023 Jul;12(18):e2203105
Exosomes promote hFOB1.19 proliferation and differentiation via LINC00520.
Wu J, Zhang L, Liu H, Zhang J, Tang P
Journal of orthopaedic surgery and research 2023 Jul 29;18(1):546
Journal of orthopaedic surgery and research 2023 Jul 29;18(1):546
Dysfunction of Caveolae-Mediated Endocytic TβRI Degradation Results in Hypersensitivity of TGF-β/Smad Signaling in Osteogenesis Imperfecta.
Shi C, Sun B, Wu H, Zhang R, Wu L, Guo L, Li C, Xi Y, Yuan W, Zhang Y, Xu G
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2023 Jan;38(1):103-118
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2023 Jan;38(1):103-118
Calcium Phosphate Bone Cements Incorporated with Black Phosphorus Nanosheets Enhanced Osteogenesis.
Ma S, Wei Y, Sun R, Xu H, Liu X, Wang Y, Liang Z, Hu Y, Lian X, Ma X, Huang D
ACS biomaterials science & engineering 2023 Jan 9;9(1):292-302
ACS biomaterials science & engineering 2023 Jan 9;9(1):292-302
Cannabidiol Rescues TNF-α-Inhibited Proliferation, Migration, and Osteogenic/Odontogenic Differentiation of Dental Pulp Stem Cells.
Yu L, Zeng L, Zhang Z, Zhu G, Xu Z, Xia J, Weng J, Li J, Pathak JL
Biomolecules 2023 Jan 6;13(1)
Biomolecules 2023 Jan 6;13(1)
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Shi X, Wu Y, Ni H, Li M, Qi B, Xu Y
International immunopharmacology 2023 Feb;115:109600
International immunopharmacology 2023 Feb;115:109600
Atf7ip Inhibits Osteoblast Differentiation via Negative Regulation of the Sp7 Transcription Factor.
Hu G, Shi X, Qu X, Han C, Hu A, Jia Z, Yang J, Liu H, Wu Y
International journal of molecular sciences 2023 Feb 21;24(5)
International journal of molecular sciences 2023 Feb 21;24(5)
Electrospun sandwich mesh structures loaded with naringenin and vitamin K(2) polycaprolactone/gelatin nanofibers synergistically promote bone regeneration.
Wang J, Shao L, Wu X, Liu C, Ni S, Dai T, Liu H, Zhao H
Materials today. Bio 2023 Dec;23:100794
Materials today. Bio 2023 Dec;23:100794
The pterostilbene-dihydropyrazole derivative Ptd-1 ameliorates vascular calcification by regulating inflammation.
Wei X, Shen Z, Zhu M, Fang M, Wang S, Zhang T, Zhang B, Yang X, Lv Z, Duan Y, Jiang M, Ma C, Li Q, Chen Y
International immunopharmacology 2023 Dec;125(Pt B):111198
International immunopharmacology 2023 Dec;125(Pt B):111198
Nodakenin alleviates ovariectomy-induced osteoporosis by modulating osteoblastogenesis and osteoclastogenesis.
Liu C, Zhao M, Chen J, Xu L, Wang K, Li G
European journal of pharmacology 2023 Dec 5;960:176121
European journal of pharmacology 2023 Dec 5;960:176121
The Synergistic Effect of Zuogui Pill and Eldecalcitol on Improving Bone Mass and Osteogenesis in Type 2 Diabetic Osteoporosis.
Shi T, Liu T, Kou Y, Rong X, Meng L, Cui Y, Gao R, Hu S, Li M
Medicina (Kaunas, Lithuania) 2023 Aug 3;59(8)
Medicina (Kaunas, Lithuania) 2023 Aug 3;59(8)
LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs.
Jiang W, Chen Y, Sun M, Huang X, Zhang H, Fu Z, Wang J, Zhang S, Lian C, Tang B, Xiang D, Wang Y, Zhang Y, Jian C, Yang C, Zhang J, Zhang D, Chen T, Zhang J
Cell reports 2023 Aug 29;42(8):112969
Cell reports 2023 Aug 29;42(8):112969
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
Zou X, Liu C, Wu X, Yuan Z, Yan F
Journal of periodontal research 2023 Apr;58(2):444-455
Journal of periodontal research 2023 Apr;58(2):444-455
A bioactive glass functional hydrogel enhances bone augmentation via synergistic angiogenesis, self-swelling and osteogenesis.
Zhao F, Yang Z, Xiong H, Yan Y, Chen X, Shao L
Bioactive materials 2023 Apr;22:201-210
Bioactive materials 2023 Apr;22:201-210
Human urine-derived stem cell exosomes delivered via injectable GelMA templated hydrogel accelerate bone regeneration.
Lu W, Zeng M, Liu W, Ma T, Fan X, Li H, Wang Y, Wang H, Hu Y, Xie J
Materials today. Bio 2023 Apr;19:100569
Materials today. Bio 2023 Apr;19:100569
Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis.
Yu C, Yang W, Yang L, Ye L, Sun R, Gu T, Ying X, Wang M, Tang R, Fan S, Yao S
ACS applied materials & interfaces 2023 Apr 26;15(16):19976-19988
ACS applied materials & interfaces 2023 Apr 26;15(16):19976-19988
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
Cai W, Sun B, Song C, Liu F, Wu Z, Liu Z
BMC complementary medicine and therapies 2023 Apr 14;23(1):121
BMC complementary medicine and therapies 2023 Apr 14;23(1):121
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Shi L, Li Y, Shi M, Li X, Li G, Cen J, Liu D, Wei C, Lin Y
Oxidative medicine and cellular longevity 2022;2022:5142381
Oxidative medicine and cellular longevity 2022;2022:5142381
Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.
Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
BioMed research international 2022;2022:4072975
BioMed research international 2022;2022:4072975
DNA Polymerase Gamma Recovers Mitochondrial Function and Inhibits Vascular Calcification by Interacted with p53.
Wang P, Wu B, You S, Lu S, Xiong S, Zou Y, Jia P, Guo X, Zhang Y, Cao L, Sun Y, Zhang N
International journal of biological sciences 2022;18(1):409-425
International journal of biological sciences 2022;18(1):409-425
Sinomenine Inhibits Orthodontic Tooth Movement and Root Resorption in Rats and Enhances Osteogenic Differentiation of PDLSCs.
Li H, Li Y, Zou J, Yang Y, Han R, Zhang J
Drug design, development and therapy 2022;16:2949-2965
Drug design, development and therapy 2022;16:2949-2965
Identification of Polysaccharides From Dipsacus asperoides and Their Effects on Osteoblast Proliferation and Differentiation in a High-Glucose Environment.
Xu D, Liu J, Zheng W, Gao Q, Gao Y, Leng X
Frontiers in pharmacology 2022;13:851956
Frontiers in pharmacology 2022;13:851956
Quercetin Attenuates Osteoporosis in Orchiectomy Mice by Regulating Glucose and Lipid Metabolism via the GPRC6A/AMPK/mTOR Signaling Pathway.
Sun J, Pan Y, Li X, Wang L, Liu M, Tu P, Wu C, Xiao J, Han Q, Da W, Ma Y, Guo Y
Frontiers in endocrinology 2022;13:849544
Frontiers in endocrinology 2022;13:849544
The mechanosensitive Piezo1 channels contribute to the arterial medial calcification.
Szabó L, Balogh N, Tóth A, Angyal Á, Gönczi M, Csiki DM, Tóth C, Balatoni I, Jeney V, Csernoch L, Dienes B
Frontiers in physiology 2022;13:1037230
Frontiers in physiology 2022;13:1037230
Effect of condylar chondrocyte exosomes on condylar cartilage osteogenesis in rats under tensile stress.
Shi Y, Shao J, Zhang Z, Zhang J, Lu H
Frontiers in bioengineering and biotechnology 2022;10:1061855
Frontiers in bioengineering and biotechnology 2022;10:1061855
Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.
Liu Z, Xu Z, Wang X, Zhang Y, Wu Y, Jiang D, Jia R
Frontiers in bioengineering and biotechnology 2022;10:1028278
Frontiers in bioengineering and biotechnology 2022;10:1028278
Downregulation of miR-30b-5p Facilitates Chondrocyte Hypertrophy and Apoptosis via Targeting Runx2 in Steroid-Induced Osteonecrosis of the Femoral Head.
Lin L, Yu Y, Liu K, Jiang Y, Zhou Z
International journal of molecular sciences 2022 Sep 24;23(19)
International journal of molecular sciences 2022 Sep 24;23(19)
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
Cai J, Liu J, Yan J, Lu X, Wang X, Li S, Mustafa K, Wang H, Xue Y, Mustafa M, Kantarci A, Xing Z
Journal of periodontal research 2022 Oct;57(5):1034-1042
Journal of periodontal research 2022 Oct;57(5):1034-1042
Hesperetin, a Promising Dietary Supplement for Preventing the Development of Calcific Aortic Valve Disease.
Zhao H, Xian G, Zeng J, Zhong G, An D, Peng Y, Hu D, Lin Y, Li J, Su S, Ning Y, Xu D, Zeng Q
Antioxidants (Basel, Switzerland) 2022 Oct 24;11(11)
Antioxidants (Basel, Switzerland) 2022 Oct 24;11(11)
Selenium-sensitive histone deacetylase 2 is required for forkhead box O3A and regulates extracellular matrix metabolism in cartilage.
Zhao Y, Guo Y, Sun M, Hussion S, Zheng Y, Huang H, Huo X, Zhao Y, Zhang F, Han Y, Ning Q, Xu P, Sun J, Lu S
Journal of bone and mineral metabolism 2022 Nov;40(6):914-926
Journal of bone and mineral metabolism 2022 Nov;40(6):914-926
Knockdown of circHIPK3 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells through activating the autophagy flux.
Zhuang Z, Jin C, Li X, Han Y, Yang Q, Huang Y, Zheng Y, Li W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22590
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22590
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
Xu P, Chang J, Ma G, Liao F, Xu T, Wu Y, Yin Z
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
BMC musculoskeletal disorders 2022 Nov 26;23(1):1020
Effects of runt-related transcription factor 2 (RUNX2) on the autophagy of rapamycin-treated osteoblasts.
Ren C, Xu Y, Liu H, Wang Z, Ma T, Li Z, Sun L, Huang Q, Zhang K, Zhang C, Cui Y, Wang Q, Lu Y
Bioengineered 2022 Mar;13(3):5262-5276
Bioengineered 2022 Mar;13(3):5262-5276
Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes.
Gautheron J, Lima L, Akinci B, Zammouri J, Auclair M, Ucar SK, Ozen S, Altay C, Bax BE, Nemazanyy I, Lenoir V, Prip-Buus C, Acquaviva-Bourdain C, Lascols O, Fève B, Vigouroux C, Noel E, Jéru I
BMC medicine 2022 Mar 28;20(1):95
BMC medicine 2022 Mar 28;20(1):95
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
Su P, Tian Y, Yin C, Wang X, Li D, Yang C, Pei J, Deng X, King S, Li Y, Qian A
Bone 2022 Jan;154:116238
Bone 2022 Jan;154:116238
Sustained release of naringin from silk-fibroin-nanohydroxyapatite scaffold for the enhancement of bone regeneration.
Zhao ZH, Ma XL, Ma JX, Kang JY, Zhang Y, Guo Y
Materials today. Bio 2022 Jan;13:100206
Materials today. Bio 2022 Jan;13:100206
A periodontal tissue regeneration strategy via biphasic release of zeolitic imidazolate framework-8 and FK506 using a uniaxial electrospun Janus nanofiber.
Sun M, Liu Y, Jiao K, Jia W, Jiang K, Cheng Z, Liu G, Luo Y
Journal of materials chemistry. B 2022 Feb 2;10(5):765-778
Journal of materials chemistry. B 2022 Feb 2;10(5):765-778
Ubiquitin-specific protease 47 is associated with vascular calcification in chronic kidney disease by regulating osteogenic transdifferentiation of vascular smooth muscle cells.
Xiao Q, Tang Y, Xia J, Luo H, Yu M, Chen S, Wang W, Pu L, Wang L, Li G, Li Y
Renal failure 2022 Dec;44(1):752-766
Renal failure 2022 Dec;44(1):752-766
A silk fibroin/chitosan/nanohydroxyapatite biomimetic bone scaffold combined with autologous concentrated growth factor promotes the proliferation and osteogenic differentiation of BMSCs and repair of critical bone defects.
Zhou Y, Liu X, She H, Wang R, Bai F, Xiang B
Regenerative therapy 2022 Dec;21:307-321
Regenerative therapy 2022 Dec;21:307-321
Nanosilica-Anchored Polycaprolactone/Chitosan Nanofibrous Bioscaffold to Boost Osteogenesis for Bone Tissue Engineering.
Ge S, Zhu X, Zhang C, Jia D, Shang W, Ding C, Yang J, Feng Y
Molecules (Basel, Switzerland) 2022 Dec 13;27(24)
Molecules (Basel, Switzerland) 2022 Dec 13;27(24)
Downregulating MFN2 Promotes the Differentiation of Induced Pluripotent Stem Cells into Mesenchymal Stem Cells through the PI3K/Akt/GSK-3β/Wnt Signaling Pathway.
Deng L, Yi S, Yin X, Li Y, Luan Q
Stem cells and development 2022 Apr;31(7-8):181-194
Stem cells and development 2022 Apr;31(7-8):181-194
MFN2 knockdown promotes osteogenic differentiation of iPSC-MSCs through aerobic glycolysis mediated by the Wnt/β-catenin signaling pathway.
Deng L, Yi S, Yin X, Li Y, Luan Q
Stem cell research & therapy 2022 Apr 12;13(1):162
Stem cell research & therapy 2022 Apr 12;13(1):162
Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.
Xu Y, Xin R, Sun H, Long D, Li Z, Liao H, Xue T, Zhang Z, Kang Y, Mao G
Frontiers in cell and developmental biology 2021;9:723759
Frontiers in cell and developmental biology 2021;9:723759
LINC00370 modulates miR-222-3p-RGS4 axis to protect against osteoporosis progression.
Li L, Zheng B, Zhang F, Luo X, Li F, Xu T, Zhao H, Shi G, Guo Y, Shi J, Sun J
Archives of gerontology and geriatrics 2021 Nov-Dec;97:104505
Archives of gerontology and geriatrics 2021 Nov-Dec;97:104505
Total glycosides from Eucommia ulmoides seed promoted osteogenic differentiation of adipose-derived mesenchymal stem cells and bone formation in ovariectomized rats through regulating Notch signaling pathway.
Zhou YH, Xie Q
Journal of orthopaedic surgery and research 2021 Nov 6;16(1):660
Journal of orthopaedic surgery and research 2021 Nov 6;16(1):660
miR-142a-5p promoted osteoblast differentiation via targeting nuclear factor IA.
Yuan H, Li M, Feng X, Zhu E, Wang B
Journal of cellular physiology 2021 Mar;236(3):1810-1821
Journal of cellular physiology 2021 Mar;236(3):1810-1821
Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization.
Éva Sikura K, Combi Z, Potor L, Szerafin T, Hendrik Z, Méhes G, Gergely P, Whiteman M, Beke L, Fürtös I, Balla G, Balla J
Journal of advanced research 2021 Jan;27:165-176
Journal of advanced research 2021 Jan;27:165-176
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
Journal of inorganic biochemistry 2021 Jan;214:111269
Journal of inorganic biochemistry 2021 Jan;214:111269
A polydopamine-assisted strontium-substituted apatite coating for titanium promotes osteogenesis and angiogenesis via FAK/MAPK and PI3K/AKT signaling pathways.
Sun Y, Li Y, Zhang Y, Wang T, Lin K, Liu J
Materials science & engineering. C, Materials for biological applications 2021 Dec;131:112482
Materials science & engineering. C, Materials for biological applications 2021 Dec;131:112482
The effects of Omarigliptin on promoting osteoblastic differentiation.
Liao F, Hu X, Chen R
Bioengineered 2021 Dec;12(2):11837-11846
Bioengineered 2021 Dec;12(2):11837-11846
The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway.
Zhang G, Liu W, Wang R, Zhang Y, Chen L, Chen A, Luo H, Zhong H, Shao L
International journal of nanomedicine 2020;15:2419-2435
International journal of nanomedicine 2020;15:2419-2435
The p53/miR-145a Axis Promotes Cellular Senescence and Inhibits Osteogenic Differentiation by Targeting Cbfb in Mesenchymal Stem Cells.
Xia C, Jiang T, Wang Y, Chen X, Hu Y, Gao Y
Frontiers in endocrinology 2020;11:609186
Frontiers in endocrinology 2020;11:609186
Rosamultin Attenuates Acute Hypobaric Hypoxia-Induced Bone Injuries by Regulation of Sclerostin and Its Downstream Signals.
Wang XM, Liu H, Li JY, Wei JX, Li X, Zhang YL, Li LZ, Zhang XZ
High altitude medicine & biology 2020 Sep;21(3):273-286
High altitude medicine & biology 2020 Sep;21(3):273-286
Celastrol attenuates arterial and valvular calcification via inhibiting BMP2/Smad1/5 signalling.
Su Z, Zong P, Chen J, Yang S, Shen Y, Lu Y, Yang C, Kong X, Sheng Y, Sun W
Journal of cellular and molecular medicine 2020 Nov;24(21):12476-12490
Journal of cellular and molecular medicine 2020 Nov;24(21):12476-12490
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement.
Jin Y, Ding L, Ding Z, Fu Y, Song Y, Jing Y, Li Q, Zhang J, Ni Y, Hu Q
Scientific reports 2020 Jul 9;10(1):11269
Scientific reports 2020 Jul 9;10(1):11269
VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I.
Li Q, Lu F, Chen T, Zhang K, Lu Y, Li X, Wang Y, Liu L, Tian Q, Xiong F, Chen D
International journal of oral science 2020 Jul 31;12(1):22
International journal of oral science 2020 Jul 31;12(1):22
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.
Sikura KÉ, Potor L, Szerafin T, Oros M, Nagy P, Méhes G, Hendrik Z, Zarjou A, Agarwal A, Posta N, Torregrossa R, Whiteman M, Fürtös I, Balla G, Balla J
British journal of pharmacology 2020 Feb;177(4):793-809
British journal of pharmacology 2020 Feb;177(4):793-809
Effects Of Triptolide On Tooth Movement And Root Resorption In Rats.
Yang F, Wang XX, Ma D, Cui Q, Zheng H, Liu XC, Zhang J
Drug design, development and therapy 2019;13:3963-3975
Drug design, development and therapy 2019;13:3963-3975
Enhancement of tenogenic differentiation of rat tendon-derived stem cells by biglycan.
Zhang YJ, Qing Q, Zhang YJ, Ning LJ, Cui J, Yao X, Luo JC, Ding W, Qin TW
Journal of cellular physiology 2019 Sep;234(9):15898-15910
Journal of cellular physiology 2019 Sep;234(9):15898-15910
TMEM18 inhibits osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells by inactivating β-catenin.
Zhang Y, Wang H, Yin T, Liu Y, Zhou W, Fan X, Wu L, Song C, Shao J, Yang T
Experimental cell research 2019 Oct 1;383(1):111491
Experimental cell research 2019 Oct 1;383(1):111491
ZnO nanoparticles inhibit the activity of Porphyromonas gingivalis and Actinomyces naeslundii and promote the mineralization of the cementum.
Wang J, Du L, Fu Y, Jiang P, Wang X
BMC oral health 2019 May 14;19(1):84
BMC oral health 2019 May 14;19(1):84
MicroRNA‑223 promotes osteoblast differentiation of MC3T3‑E1 cells by targeting histone deacetylase 2.
Chen J, He G, Wang Y, Cai D
International journal of molecular medicine 2019 Mar;43(3):1513-1521
International journal of molecular medicine 2019 Mar;43(3):1513-1521
Potential Role of H-Ferritin in Mitigating Valvular Mineralization.
Sikura KÉ, Potor L, Szerafin T, Zarjou A, Agarwal A, Arosio P, Poli M, Hendrik Z, Méhes G, Oros M, Posta N, Beke L, Fürtös I, Balla G, Balla J
Arteriosclerosis, thrombosis, and vascular biology 2019 Mar;39(3):413-431
Arteriosclerosis, thrombosis, and vascular biology 2019 Mar;39(3):413-431
Histone demethylase KDM7A reciprocally regulates adipogenic and osteogenic differentiation via regulation of C/EBPα and canonical Wnt signalling.
Yang X, Wang G, Wang Y, Zhou J, Yuan H, Li X, Liu Y, Wang B
Journal of cellular and molecular medicine 2019 Mar;23(3):2149-2162
Journal of cellular and molecular medicine 2019 Mar;23(3):2149-2162
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
Wang S, Xu C, Yu S, Wu X, Jie Z, Dai H
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
Hypoxia Triggers Osteochondrogenic Differentiation of Vascular Smooth Muscle Cells in an HIF-1 (Hypoxia-Inducible Factor 1)-Dependent and Reactive Oxygen Species-Dependent Manner.
Balogh E, Tóth A, Méhes G, Trencsényi G, Paragh G, Jeney V
Arteriosclerosis, thrombosis, and vascular biology 2019 Jun;39(6):1088-1099
Arteriosclerosis, thrombosis, and vascular biology 2019 Jun;39(6):1088-1099
Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification.
Gu J, Lu Y, Deng M, Qiu M, Tian Y, Ji Y, Zong P, Shao Y, Zheng R, Zhou B, Sun W, Kong X
Experimental & molecular medicine 2019 Jul 10;51(7):1-14
Experimental & molecular medicine 2019 Jul 10;51(7):1-14
LncRNA ODIR1 inhibits osteogenic differentiation of hUC-MSCs through the FBXO25/H2BK120ub/H3K4me3/OSX axis.
He S, Yang S, Zhang Y, Li X, Gao D, Zhong Y, Cao L, Ma H, Liu Y, Li G, Peng S, Shuai C
Cell death & disease 2019 Dec 11;10(12):947
Cell death & disease 2019 Dec 11;10(12):947
Inhibition of pyroptosis attenuates Staphylococcus aureus-induced bone injury in traumatic osteomyelitis.
Zhu X, Zhang K, Lu K, Shi T, Shen S, Chen X, Dong J, Gong W, Bao Z, Shi Y, Ma Y, Teng H, Jiang Q
Annals of translational medicine 2019 Apr;7(8):170
Annals of translational medicine 2019 Apr;7(8):170
The microRNA-10a/ID3/RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament.
Xu C, Zhang H, Gu W, Wu H, Chen Y, Zhou W, Sun B, Shen X, Zhang Z, Wang Y, Liu Y, Yuan W
Scientific reports 2018 Jun 15;8(1):9225
Scientific reports 2018 Jun 15;8(1):9225
Aryl Hydrocarbon Receptor Antagonists Mitigate the Effects of Dioxin on Critical Cellular Functions in Differentiating Human Osteoblast-Like Cells.
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International journal of molecular sciences 2018 Jan 11;19(1)
International journal of molecular sciences 2018 Jan 11;19(1)
The effect of different hydroxyapatite microparticles on the osteogenic differentiation of MC3T3-E1 preosteoblasts.
Xu W, Xu C, Yi J, Dai H
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Journal of materials chemistry. B 2018 Aug 28;6(32):5234-5242
APE1/Ref-1 Inhibits Phosphate-Induced Calcification and Osteoblastic Phenotype Changes in Vascular Smooth Muscle Cells.
Lee KM, Lee EO, Lee YR, Joo HK, Park MS, Kim CS, Choi S, Jeong JO, Jeon BH
International journal of molecular sciences 2017 Sep 25;18(10)
International journal of molecular sciences 2017 Sep 25;18(10)
Effect of pioglitazone on the calcification of rat vascular smooth muscle cells through the downregulation of the Wnt/β‑catenin signaling pathway.
Gao M, Chen T, Wu L, Zhao X, Mao H, Xing C
Molecular medicine reports 2017 Nov;16(5):6208-6213
Molecular medicine reports 2017 Nov;16(5):6208-6213
Graphene/single-walled carbon nanotube hybrids promoting osteogenic differentiation of mesenchymal stem cells by activating p38 signaling pathway.
Yan X, Yang W, Shao Z, Yang S, Liu X
International journal of nanomedicine 2016;11:5473-5484
International journal of nanomedicine 2016;11:5473-5484
The In Vitro and In Vivo Osteogenic Capability of the Extraction Socket-Derived Early Healing Tissue.
Luo J, Xu J, Cai J, Wang L, Sun Q, Yang P
Journal of periodontology 2016 Sep;87(9):1057-66
Journal of periodontology 2016 Sep;87(9):1057-66
Osteogenic differentiation of human lens epithelial cells might contribute to lens calcification.
Balogh E, Tóth A, Tolnai E, Bodó T, Bányai E, Szabó DJ, Petrovski G, Jeney V
Biochimica et biophysica acta 2016 Sep;1862(9):1724-31
Biochimica et biophysica acta 2016 Sep;1862(9):1724-31
Resveratrol Ameliorated Vascular Calcification by Regulating Sirt-1 and Nrf2.
Zhang P, Li Y, Du Y, Li G, Wang L, Zhou F
Transplantation proceedings 2016 Dec;48(10):3378-3386
Transplantation proceedings 2016 Dec;48(10):3378-3386
Hydrogen peroxide prevents vascular calcification induced ROS production by regulating Nrf-2 pathway.
Zhang W, Li Y, Ding H, Du Y, Wang L
Renal failure 2016 Aug;38(7):1099-106
Renal failure 2016 Aug;38(7):1099-106
The Role and Mechanism of α-Klotho in the Calcification of Rat Aortic Vascular Smooth Muscle Cells.
Chen T, Mao H, Chen C, Wu L, Wang N, Zhao X, Qian J, Xing C
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BioMed research international 2015;2015:194362
Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways.
Yuan ZS, Zhou YZ, Liao XB, Luo JW, Shen KJ, Hu YR, Gu L, Li JM, Tan CM, Chen HM, Zhou XM
Amino acids 2015 Dec;47(12):2475-82
Amino acids 2015 Dec;47(12):2475-82
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- ROS1728 cells were subjected to SDS PAGE followed by western blot with 20700-1-AP( RUNX2 Antibody) at dilution of 1:600
- Other comments
- WB
