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Protein structure
TNFRSF8
TNF receptor superfamily member 8CD30, D1S166E, KI-1
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  A700-055 |
Monoclonal |
WB
ICC
IP
IHC
FC
OA
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| antibodies-online | ABIN1997474 |
2 references | Polyclonal |
WB
EL
IP
IHC
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| Novus Biologicals | NBP2-52682-0.2mg |
Monoclonal |
EL
ICC
IHC
FC
FA
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| Acris Antibodies GmbH | AM20190AF-N |
Monoclonal |
WB
IP
IHC
FC
|
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| LSBio | LS-C175657 |
Monoclonal |
WB
IHC
|
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