orb317428

antibody from Biorbyt

Targeting: TNFRSF8 CD30, D1S166E, KI-1

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

orb317428

Provider

Biorbyt

Product name

CD30 Antibody Cocktail

Antibody type

Monoclonal

Description

Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin's disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This mAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

Reactivity

Human

Host

Mouse

Antibody clone number

Ber-H2 + CD30/412

Vial size

100 ul

Storage

Store the CD30 antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).