Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [676]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 60186-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60186-1-Ig, RRID:AB_10793718
- Product name
- Cyclin D1 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Cyclin D1 antibody (Cat. #60186-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2G3G5
- Vial size
- 20ul, 150ul
Submitted references CYR61 Acts as an Intracellular Microtubule-Associated Protein and Coordinates Mitotic Progression via PLK1-FBW7 Pathway.
CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis.
Brucine Suppresses Malignant Progression of Prostate Cancer by Decreasing Sarcosine Accumulation via Downregulation of GNMT in the Glycine/sarcosine Metabolic Pathway.
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.
IDH1 mutation produces R-2-hydroxyglutarate (R-2HG) and induces mir-182-5p expression to regulate cell cycle and tumor formation in glioma.
Combined SET7/9 and CDK4 inhibition act synergistically against osteosarcoma.
Copper Chaperone Atox1 Protected the Cochlea From Cisplatin by Regulating the Copper Transport Family and Cell Cycle.
Cynaroside Induces G1 Cell Cycle Arrest by Downregulating Cell Division Cycle 25A in Colorectal Cancer.
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
ART1 knockdown decreases the IL-6-induced proliferation of colorectal cancer cells.
YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia.
CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8 + T cell response.
β-catenin/TCF4-induced SCUBE3 upregulation promotes ovarian cancer development via HIF-1 signaling pathway.
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
ZNF862 induces cytostasis and apoptosis via the p21-RB1 and Bcl-xL-Caspase 3 signaling pathways in human gingival fibroblasts.
Bioinspired engineering ADSC nanovesicles thermosensitive hydrogel enhance autophagy of dermal papilla cells for androgenetic alopecia treatment.
Overexpression of FHL1 suppresses papillary thyroid cancer proliferation and progression via inhibiting Wnt/β-catenin pathway.
Melatonin promotes cell cycle progression of neural stem cells subjected to manganese via Nurr1.
Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells.
SPP1 could be an immunological and prognostic biomarker: From pan-cancer comprehensive analysis to osteosarcoma validation.
let-7g sensitized liver cancer cells to 5-fluorouracil by downregulating ABCC10 expression.
TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma.
MiR-199a-5p inhibits dermal papilla cells proliferation by regulating VEGFA expression in cashmere goat.
CHEK2 knockout is a therapeutic target for TP53-mutated hepatocellular carcinoma.
Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Cepharanthine suppresses APC-mutant colorectal cancers by down-regulating the expression of β-catenin.
Schisandrin B promotes hepatic differentiation from human umbilical cord mesenchymal stem cells.
ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner.
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
Dendrobium nobile active ingredient Dendrobin A against hepatocellular carcinoma via inhibiting nuclear factor kappa-B signaling.
Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis.
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Matairesinoside, a novel inhibitor of TMEM16A ion channel, loaded with functional hydrogel for lung cancer treatment.
TuBG1 promotes hepatocellular carcinoma via ATR/P53-apoptosis and cycling pathways.
Cadmium disrupts spermatogenic cell cycle via piRNA-DQ717867/p53 pathway.
Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer.
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
Peptide Inhibitor Targeting the Extraterminal Domain in BRD4 Potently Suppresses Breast Cancer Both In Vitro and In Vivo.
Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma.
PRMT6-mediated transcriptional activation of ythdf2 promotes glioblastoma migration, invasion, and emt via the wnt-β-catenin pathway.
The role of miR-222-2p in exosomes secreted by hexavalent chromium-induced premature senescent hepatocytes as a SASP component.
Isolation and Cultivation of Vascular Smooth Muscle Cells from the Mouse Circle of Willis.
NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner.
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
PRMT7 Inhibits the Proliferation and Migration of Gastric Cancer Cells by Suppressing the PI3K/AKT Pathway via PTEN.
HSP105 suppresses the progression of cutaneous squamous cell carcinoma by activating the P53 signaling pathway.
Prognostic and therapeutic implications of iron-related cell death pathways in acute myeloid leukemia.
Role of UDP-glucose ceramide glucosyltransferase in venous malformation.
LINC02870 facilitates SNAIL translation to promote hepatocellular carcinoma progression.
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression.
CCDC85C suppresses colorectal cancer cells proliferation and metastasis through activating GSK-3β and promoting β-catenin degradation.
SUMO-Activating Enzyme Subunit 1 Is Associated with Poor Prognosis, Tumor Progression, and Radio-Resistance in Colorectal Cancer.
Ar-turmerone inhibits the proliferation and mobility of glioma by downregulating cathepsin B.
Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.
DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
MTHFD2 promotes PD-L1 expression via activation of the JAK/STAT signalling pathway in bladder cancer.
Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.
Role of Nucleobindin-2 in the Clinical Pathogenesis and Treatment Resistance of Glioblastoma.
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
A pan-cancer analysis of the role of HOXD1, HOXD3, and HOXD4 and validation in renal cell carcinoma.
IGF2BP2 acts as a m(6)A modification regulator in laryngeal squamous cell carcinoma through facilitating CDK6 mRNA stabilization.
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice.
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
IL-7 promotes CD19-directed CAR-T cells proliferation through miRNA-98-5p by targeting CDKN1A.
A large-scale transcriptional analysis reveals herb-derived ginsenoside F2 suppressing hepatocellular carcinoma via inhibiting STAT3.
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
Tripartite motif 31 drives gastric cancer cell proliferation and invasion through activating the Wnt/β-catenin pathway by regulating Axin1 protein stability.
GAD1-mediated GABA elicits aggressive characteristics of human oral cancer cells.
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
Targeting diacylglycerol kinase α impairs lung tumorigenesis by inhibiting cyclin D3.
The High Level of RANKL Improves IκB/p65/Cyclin D1 Expression and Decreases p-Stat5 Expression in Firm Udder of Dairy Goats.
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Microtubule-associated protein 4 promotes epithelial mesenchymal transition in hepatocellular cancer cells via regulating GSK3β/β-catenin pathway.
Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity.
The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury.
Pan-cancer analysis of PCAT6 and its effect on oesophageal squamous cell carcinoma cell proliferation and migration.
Human umbilical cord mesenchymal stem cells conditioned medium exerts anti-tumor effects on KGN cells in a cell density-dependent manner through activation of the Hippo pathway.
Ursolic acid nanoparticles for glioblastoma therapy.
MicroRNA-137 inhibits pituitary prolactinoma proliferation by targeting AKT2.
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway.
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma.
eIF3a sustains non-small cell lung cancer stem cell-like properties by promoting YY1-mediated transcriptional activation of β-catenin.
Ethyl acetate extract of Antenoron Filiforme inhibits the proliferation of triple negative breast cancer cells via suppressing Skp2/p21 signaling axis.
Targeting CDK12 obviates the malignant phenotypes of colorectal cancer through the Wnt/β-catenin signaling pathway.
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
ZYY-B-2, a novel ALK inhibitor, overcomes resistance to ceritinib by inhibiting P-gp function and induces apoptosis through mitochondrial pathway in ceritinib-resistant H2228 cells.
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
Analysis of Promoter Methylation of the Bovine FOXO1 Gene and Its Effect on Proliferation and Differentiation of Myoblasts.
Triptonide inhibits growth and metastasis in HCC by suppressing EGFR/PI3K/AKT signaling.
Effects of the CDC10 (Septin 7) Gene on the Proliferation and Differentiation of Bovine Intramuscular Preadipocyte and 3T3-L1 Cells.
Krüppel-like Factor 7 inhibits proliferation and migration of pulmonary smooth muscle cells via p21 activation.
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening.
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
ANXA3, associated with YAP1 regulation, participates in the proliferation and chemoresistance of cervical cancer cells.
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
Effects of dietary folic acid supplementation on lactation performance and mammary epithelial cell development of dairy cows and its regulatory mechanism.
Exogenous H(2)S alleviates senescence of glomerular mesangial cells through up-regulating mitophagy by activation of AMPK-ULK1-PINK1-parkin pathway in mice.
NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis.
TC2N Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Targeting the Wnt/β-Catenin Signaling Pathway.
LINC00921 reduces lung cancer radiosensitivity by destabilizing NUDT21 and driving aberrant MED23 alternative polyadenylation.
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Aberrant epithelial cell interaction promotes esophageal squamous-cell carcinoma development and progression.
CD56 polysialylation promotes the tumorigenesis and progression via the Hedgehog and Wnt/β-catenin signaling pathways in clear cell renal cell carcinoma.
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer.
Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.
Histone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia.
High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.
Knockdown of KDM5B Leads to DNA Damage and Cell Cycle Arrest in Granulosa Cells via MTF1.
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer.
8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells.
Upregulation of TMEM40 is associated with the malignant behavior and promotes tumor progression in cervical cancer.
Structural Characterization and Anti-breast Cancer Activity in vitro of a Novel Polysaccharide From Cymbopogon citratus.
Intervention Mechanism of Hunag-Lian Jie-Du Decoction on Canonical Wnt/β-Catenin Signaling Pathway in Psoriasis Mouse Model.
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.
CCDC65, a Gene Knockout that leads to Early Death of Mice, acts as a potentially Novel Tumor Suppressor in Lung Adenocarcinoma.
CAMTA1 gene affects the ischemia-reperfusion injury by regulating CCND1.
Chrysin Ameliorates Influenza Virus Infection in the Upper Airways by Repressing Virus-Induced Cell Cycle Arrest and Mitochondria-Dependent Apoptosis.
METTL3/m(6)A/IFIT2 regulates proliferation, invasion and immunity in esophageal squamous cell carcinoma.
Targeting type Iγ phosphatidylinositol phosphate kinase overcomes oxaliplatin resistance in colorectal cancer.
E2F1-mediated GINS2 transcriptional activation promotes tumor progression through PI3K/AKT/mTOR pathway in hepatocellular carcinoma.
INPP4B inhibits glioma cell proliferation and immune escape via inhibition of the PI3K/AKT signaling pathway.
Synergistic effects of nab-PTX and anti-PD-1 antibody combination against lung cancer by regulating the Pi3K/AKT pathway through the Serpinc1 gene.
Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.
Increased Methyl-CpG-Binding Domain Protein 2 Promotes Cigarette Smoke-Induced Pulmonary Hypertension.
HRK inhibits colorectal cancer cells proliferation by suppressing the PI3K/AKT/mTOR pathway.
Identification and validation of a potential key gene SGOL1 for poor prognosis in hepatocellular carcinoma based on a bioinformatics approach.
A long noncoding RNA GTF2IRD2P1 suppresses cell proliferation in bladder cancer by inhibiting the Wnt/β‑catenin signaling pathway.
SERPINA5 promotes tumour cell proliferation by modulating the PI3K/AKT/mTOR signalling pathway in gastric cancer.
Combined treatment with dihydrotestosterone and lipopolysaccharide modulates prostate homeostasis by upregulating TNF-α from M1 macrophages and promotes proliferation of prostate stromal cells.
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation through the Chi-miR-214-3p/β-Catenin Axis in Cashmere Goats.
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE.
Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy.
CTPS cytoophidia formation affects cell cycle progression and promotes TSN‑induced apoptosis of MKN45 cells.
HCV Core protein represses DKK3 expression via epigenetic silencing and activates the Wnt/β-catenin signaling pathway during the progression of HCC.
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Transfer RNA-derived fragment 5'tRF-Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen-related cell adhesion molecule 1.
RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Hepatocyte-derived VEGFA accelerates the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via activating hepatic stellate cells.
Lysine stimulates the development of the murine mammary gland at puberty via PI3K/AKT/mTOR signalling axis.
Blockade of c-Met-Mediated Signaling Pathways by E7050 Suppresses Growth and Promotes Apoptosis in Multidrug-Resistant Human Uterine Sarcoma Cells.
Discovery of a Novel Bloom's Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer.
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
Potential mechanisms underlying the promoting effects of 3D collagen scaffold culture on stemness and drug resistance of glioma cells.
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway.
In vitro and in vivo anti-lymphoma effects of Ophiorrhiza pumila extract.
Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.
Arylquin 1 (Potent Par-4 Secretagogue) Inhibits Tumor Progression and Induces Apoptosis in Colon Cancer Cells.
Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway.
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
A novel mechanism of the lncRNA PTTG3P/miR-142-5p/JAG1 axis modulating tongue cancer cell phenotypes through the Notch1 signaling.
Cyclin D1 mediated by the nuclear translocation of nuclear factor kappa B exerts an oncogenic role in lung cancer.
Pseudophosphatase STYX is induced by Helicobacter pylori and promotes gastric cancer progression by inhibiting FBXO31 function.
Long noncoding RNA Gm31629 protects against mucosal damage in experimental colitis via YB-1/E2F pathway.
HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway.
Transcription Factor Specificity Protein 1 Regulates Inflammation and Fibrin Deposition in Nasal Polyps Via the Regulation of microRNA-125b and the Wnt/β-catenin Signaling Pathway.
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H(2)S in Diabetes.
Paired box 8 facilitates the c-MYC related cell cycle progress in TP53-mutation uterine corpus endometrial carcinoma through interaction with DDX5.
Near-Infrared Light-Responsive Nanoinhibitors for Tumor Suppression through Targeting and Regulating Anion Channels.
Caffeic Acid, an Active Ingredient in Coffee, Combines with DOX for Multitarget Combination Therapy of Lung Cancer.
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Knockdown of EphB3 inhibits cell proliferation partly through the AKT signaling pathway and represses epithelial-mesenchymal transition in esophageal squamous cell carcinoma.
Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies.
Betulinic acid self-assembled nanoparticles for effective treatment of glioblastoma.
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
PRUNE2 inhibits progression of colorectal cancer in vitro and in vivo.
The miR-34a/WNT7B modulates the sensitivity of cholangiocarcinoma cells to p53-mediated photodynamic therapy toxicity.
FERMT1 contributes to the migration and invasion of nasopharyngeal carcinoma through epithelial-mesenchymal transition and cell cycle arrest.
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Characterization and functional analysis of lncRNA2690 in regulating the growth cycle of the hair follicle in rabbits.
ALG8 Fuels Stemness Through Glycosylation of the WNT/Beta-Catenin Signaling Pathway in Colon Cancer.
PRRX1 promotes colorectal cancer stemness and chemoresistance via the JAK2/STAT3 axis by targeting IL-6.
miR-29b-3p inhibits 22Rv1 prostate cancer cell proliferation through the YWHAE/BCL-2 regulatory axis.
NSUN2-mediated RNA m(5)C modification modulates uveal melanoma cell proliferation and migration.
LAP3 contributes to IFN-γ-induced arginine depletion and malignant transformation of bovine mammary epithelial cells.
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c-Myc pathway in patients with estrogen receptor-positive breast cancer.
DNA Methylation Mediates lncRNA2919 Regulation of Hair Follicle Regeneration.
The effects of Jiawei Duhuo Jisheng mixture on Wnt/β-catenin signaling pathway in the synovium inflamed by knee osteoarthritis: An in vitro and in vivo experiment.
Dematin inhibits glioblastoma malignancy through RhoA-mediated CDKs downregulation and cytoskeleton remodeling.
Elevated FAM84B promotes cell proliferation via interacting with NPM1 in esophageal squamous cell carcinoma.
Bolbostemma paniculatum (Maxim.) Franquet extract suppresses the development of colorectal cancer through downregulation of PI3K/Akt pathway.
CYLD deficiency enhances metabolic reprogramming and tumor progression in nasopharyngeal carcinoma via PFKFB3.
β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway.
CDK5RAP3 acts as a putative tumor inhibitor in papillary thyroid carcinoma via modulation of Akt/GSK-3β/Wnt/β-catenin signaling.
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.
Effect of Photodynamic Therapy on Gemcitabine-Resistant Cholangiocarcinoma in vitro and in vivo Through KLF10 and EGFR.
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
NAP1L1 Functions as a Tumor Promoter via Recruiting Hepatoma-Derived Growth Factor/c-Jun Signal in Hepatocellular Carcinoma.
CORO6 Promotes Cell Growth and Invasion of Clear Cell Renal Cell Carcinoma via Activation of WNT Signaling.
LHPP-Mediated Histidine Dephosphorylation Suppresses the Self-Renewal of Mouse Embryonic Stem Cells.
17β-Estradiol Inhibits Proliferation and Oxidative Stress in Vascular Smooth Muscle Cells by Upregulating BHLHE40 Expression.
Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.
Transcription Factors BARX1 and DLX4 Contribute to Progression of Clear Cell Renal Cell Carcinoma via Promoting Proliferation and Epithelial-Mesenchymal Transition.
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma.
Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma.
Increased Collagen Type V α2 (COL5A2) in Colorectal Cancer is Associated with Poor Prognosis and Tumor Progression.
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
A novel function for cyclin D1 as a transcriptional role in oncogenesis and tumor development by ChIP-Seq and RNA-Seq.
Lenvatinib induces anticancer activity in gallbladder cancer by targeting AKT.
Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder Cancer.
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Therapeutic Potential of CUDC-907 (Fimepinostat) for Hepatocarcinoma Treatment Revealed by Tumor Spheroids-Based Drug Screening.
Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for Treatment of Lung Adenocarcinoma.
SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer.
tRNA-Derived Fragment tRF-Glu-TTC-027 Regulates the Progression of Gastric Carcinoma via MAPK Signaling Pathway.
The lncRNA CASC2 Modulates Hepatocellular Carcinoma Cell Sensitivity and Resistance to TRAIL Through Apoptotic and Non-Apoptotic Signaling.
Role of Notch pathway in effect of mono-2-ethylhexyl phthalate on the proliferation and cell cycle of SH-SY5Y cell.
TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma.
The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy.
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.
Bromodomain-containing protein 9 promotes hepatocellular carcinoma progression via activating the Wnt/β-catenin signaling pathway.
LncAY controls BMI1 expression and activates BMI1/Wnt/β-catenin signaling axis in hepatocellular carcinoma.
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Silent information regulator 2 promotes clear cell renal cell carcinoma progression through deacetylation and small ubiquitin-related modifier 1 modification of glucose 6-phosphate dehydrogenase.
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
TMEM16A, a Homoharringtonine Receptor, as a Potential Endogenic Target for Lung Cancer Treatment.
Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer.
Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness.
Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/β-catenin pathway in hepatocellular carcinoma.
NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth.
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways.
Niacin stimulates EPH4EV mammary epithelial cell proliferation and mammary gland development in pubertal mice through activation of AKT/mTOR and ERK1/2 signaling pathways.
Expression of COX-2 and Nrf2/GPx3 in the anterior vaginal wall tissues of women with pelvic organ prolapse.
Pyrvinium pamoate can overcome artemisinin's resistance in anaplastic thyroid cancer.
Activity Components from Gynostemma pentaphyllum for Preventing Hepatic Fibrosis and of Its Molecular Targets by Network Pharmacology Approach.
CUX1 Enhances Pancreatic Cancer Formation by Synergizing with KRAS and Inducing MEK/ERK-Dependent Proliferation.
Long intergenic non-coding RNA 00473 promotes proliferation and migration of gastric cancer via the miR-16-5p/CCND2 axis and by regulating AQP3.
Nucleolar and spindle‑associated protein 1 promotes non‑small cell lung cancer progression and serves as an effector of myocyte enhancer factor 2D.
Down-regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p.
LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis.
miRNA in food simultaneously controls animal viral disease and human tumorigenesis.
The influence of phenolic environmental estrogen on the transcriptome of uterine leiomyoma cells: A whole transcriptome profiling-based analysis.
FoxP3-miR-150-5p/3p suppresses ovarian tumorigenesis via an IGF1R/IRS1 pathway feedback loop.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway.
CENPE contributes to pulmonary vascular remodeling in pulmonary hypertension.
Effect of fenofibrate on proliferation of SMMC-7721 cells via regulating cell cycle.
METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
BACH1 is transcriptionally inhibited by TET1 in hepatocellular carcinoma in a microRNA-34a-dependent manner to regulate autophagy and inflammation.
miRNA-194 predicts favorable prognosis in gastric cancer and inhibits gastric cancer cell growth by targeting CCND1.
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis.
Circular RNA-DPP4 serves an oncogenic role in prostate cancer progression through regulating miR-195/cyclin D1 axis.
Long noncoding RNA GAS5 accelerates diabetic wound healing and promotes lymphangiogenesis via miR-217/Prox1 axis.
Maternally expressed 3 protects the intestinal barrier from cardiac arrest-induced ischemia/reperfusion injury via miR-34a-3p/sirtuin 1/nuclear factor kappa B signaling.
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
Absence of the MFG-E8 gene prevents hypoxia-induced pulmonary hypertension in mice.
The circular RNA circZFR phosphorylates Rb promoting cervical cancer progression by regulating the SSBP1/CDK2/cyclin E1 complex.
Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma.
Knockdown of CENPF inhibits the progression of lung adenocarcinoma mediated by ERβ2/5 pathway.
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Sericin inhibits MDA‑MB‑468 cell proliferation via the PI3K/Akt pathway in triple‑negative breast cancer.
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
Synergistic inhibitory effect of Smo inhibitor jervine and its combination with decitabine can target Hedgehog signaling pathway to inhibit myelodysplastic syndrome cell line.
Cell division cycle associated 8: A novel diagnostic and prognostic biomarker for hepatocellular carcinoma.
The protective mechanism of Klotho gene-modified bone marrow mesenchymal stem cells on acute kidney injury induced by rhabdomyolysis.
S100A11 regulates nasal epithelial cell remodeling and inflammation in CRSwNPs via the RAGE-mediated AMPK-STAT3 pathway.
Senescence marker protein 30 inhibits tumor growth by reducing HDAC4 expression in non-small cell lung cancer.
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell.
SETD4 in the Proliferation, Migration, Angiogenesis, Myogenic Differentiation and Genomic Methylation of Bone Marrow Mesenchymal Stem Cells.
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
LncRNA LINC00680 promotes lung adenocarcinoma growth via binding to GATA6 and canceling GATA6-mediated suppression of SOX12 expression.
Hybrid-cell membrane-coated nanocomplex-loaded chikusetsusaponin IVa methyl ester for a combinational therapy against breast cancer assisted by Ce6.
SIRT4 is the molecular switch mediating cellular proliferation in colorectal cancer through GLS mediated activation of AKT/GSK3β/CyclinD1 pathway.
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
THAP11 Functions as a Tumor Suppressor in Gastric Cancer through Regulating c-Myc Signaling Pathways.
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
Cancer Cell enters reversible quiescence through Intracellular Acidification to resist Paclitaxel Cytotoxicity.
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Derlin-1 Promotes the Progression of Human Hepatocellular Carcinoma via the Activation of AKT Pathway.
Up-Regulated CCDC34 Contributes to the Proliferation and Metastasis of Hepatocellular Carcinoma.
ΔNp63α promotes the expression and nuclear translocation of PTEN, leading to cisplatin resistance in oral cancer cells.
Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.
AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.
Activated STAT3 Could Reduce Survival in Patients with Esophageal Squamous Cell Carcinoma by Up-regulating VEGF and Cyclin D1 Expression.
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1.
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.
Aristolochic acid induces renal fibrosis by arresting proximal tubular cells in G2/M phase mediated by HIF-1α.
PAK6 promotes cervical cancer progression through activation of the Wnt/β-catenin signaling pathway.
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
UBAC2 promotes bladder cancer proliferation through BCRC-3/miRNA-182-5p/p27 axis.
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
miR‑483‑3p promotes the osteogenesis of human osteoblasts by targeting Dikkopf 2 (DKK2) and the Wnt signaling pathway.
Oncogenic gene RGC-32 is a direct target of miR-26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling.
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells.
PRMT5/Wnt4 axis promotes lymph-node metastasis and proliferation of laryngeal carcinoma.
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26.
Mitochondrial UQCC3 Modulates Hypoxia Adaptation by Orchestrating OXPHOS and Glycolysis in Hepatocellular Carcinoma.
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Metformin suppresses proliferation and invasion of drug-resistant breast cancer cells by activation of the Hippo pathway.
Kp-10 promotes bovine mammary epithelial cell proliferation by activating GPR54 and its downstream signaling pathways.
MS-275 combined with cisplatin exerts synergistic antitumor effects in human esophageal squamous cell carcinoma cells.
MiR-193b-5p inhibits proliferation and enhances radio-sensitivity by downregulating the AKT/mTOR signaling pathway in tongue cancer.
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Increased expression of hematological and neurological expressed 1 (HN1) is associated with a poor prognosis of hepatocellular carcinoma and its knockdown inhibits cell growth and migration partly by down-regulation of c-Met.
Ablation of Gsa impairs renal tubule proliferation after injury via CDK2/cyclin E.
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
ASH2L is involved in promotion of endometrial cancer progression via upregulation of PAX2 transcription.
Radiation-Induced DNMT3B Promotes Radioresistance in Nasopharyngeal Carcinoma through Methylation of p53 and p21.
HnRNP A1 - mediated alternative splicing of CCDC50 contributes to cancer progression of clear cell renal cell carcinoma via ZNF395.
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
miR‑96 exerts an oncogenic role in the progression of cervical cancer by targeting CAV‑1.
Garcinol acts as an antineoplastic agent in human gastric cancer by inhibiting the PI3K/AKT signaling pathway.
PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells.
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
The interaction of tumor cells and myeloid-derived suppressor cells in chronic myelogenous leukemia.
Transcription factor E2F4 is a positive regulator of milk biosynthesis and proliferation of bovine mammary epithelial cells.
Par6 regulates cell cycle progression through enhancement of Akt/PI3K/GSK-3β signaling pathway activation in glioma.
LINC00511 contributes to glioblastoma tumorigenesis and epithelial-mesenchymal transition via LINC00511/miR-524-5p/YB1/ZEB1 positive feedback loop.
SOX6 suppresses the development of lung adenocarcinoma by regulating expression of p53, p21(CIPI) , cyclin D1 and β-catenin.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
TOB1 suppresses proliferation in K-Ras wild-type pancreatic cancer.
Acetyl-11-keto-β-boswellic acid triggers premature senescence via induction of DNA damage accompanied by impairment of DNA repair genes in hepatocellular carcinoma cells in vitro and in vivo.
Pizotifen inhibits the proliferation and invasion of gastric cancer cells.
Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.
Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress.
Heat-Shock protein A12A is a novel PCNA-binding protein and promotes hepatocellular carcinoma growth.
Sirtuin 5 regulates the proliferation, invasion and migration of prostate cancer cells through acetyl-CoA acetyltransferase 1.
Notch3 is involved in the proliferation of renal cancer cells via regulation of cell cycle progression and HIF-2α.
MicroRNA-1236-3p inhibits human osteosarcoma growth.
GEF-independent Ran activation shifts a fraction of the protein to the cytoplasm and promotes cell proliferation.
S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression.
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
TMEM16A-inhibitor loaded pH-responsive nanoparticles: A novel dual-targeting antitumor therapy for lung adenocarcinoma.
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Long Non-coding RNA PEBP1P2 Suppresses Proliferative VSMCs Phenotypic Switching and Proliferation in Atherosclerosis.
Prazosin inhibits the proliferation and survival of acute myeloid leukaemia cells through down-regulating TNS1.
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Celastrol attenuates ox-LDL-induced mesangial cell proliferation via suppressing NLRP3 inflammasome activation.
GRP78 regulates milk biosynthesis and the proliferation of bovinemammaryepithelial cells through the mTOR signaling pathway.
Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.
LncRNA FEZF1-AS1 Promotes TGF-β2-Mediated Proliferation and Migration in Human Lens Epithelial Cells SRA01/04.
Strand-specific miR-28-3p and miR-28-5p have differential effects on nasopharyngeal cancer cells proliferation, apoptosis, migration and invasion.
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Adiponectin Suppresses Human Pancreatic Cancer Growth through Attenuating the β-Catenin Signaling Pathway.
Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
Hypermethylation Of ADHFE1 Promotes The Proliferation Of Colorectal Cancer Cell Via Modulating Cell Cycle Progression.
The effect of MTHFD2 on the proliferation and migration of colorectal cancer cell lines.
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism.
Dimethyl fumarate suppresses hepatocellular carcinoma progression via activating SOCS3/JAK1/STAT3 signaling pathway.
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle.
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension.
NUCKS1 is a novel regulator of milk synthesis in and proliferation of mammary epithelial cells via the mTOR signaling pathway.
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
CircNR3C1 inhibits proliferation of bladder cancer cells by sponging miR-27a-3p and downregulating cyclin D1 expression.
miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells.
Regulation of circadian rhythms by NEAT1 mediated TMAO-induced endothelial proliferation: A protective role of asparagus extract.
Resveratrol inhibits the proliferation of estrogen receptor-positive breast cancer cells by suppressing EZH2 through the modulation of ERK1/2 signaling.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis.
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
LXRα-mediated downregulation of EGFR suppress colorectal cancer cell proliferation.
RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.
O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion.
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells.
Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM.
Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway.
Agmatinase promotes the lung adenocarcinoma tumorigenesis by activating the NO-MAPKs-PI3K/Akt pathway.
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
piRNA-DQ722010 contributes to prostate hyperplasia of the male offspring mice after the maternal exposed to microcystin-leucine arginine.
Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia.
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
miR-340-FHL2 axis inhibits cell growth and metastasis in ovarian cancer.
MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/β-catenin pathway in acute myeloid leukemia.
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Downregulation of EIF5A2 by miR-221-3p inhibits cell proliferation, promotes cell cycle arrest and apoptosis in medulloblastoma cells.
Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression.
UNBS5162 inhibits SKOV3 ovarian cancer cell proliferation by regulating the PI3K/AKT signalling pathway.
A Molecular Targeted Immunotherapeutic Strategy for Ulcerative Colitis via Dual-targeting Nanoparticles Delivering miR-146b to Intestinal Macrophages.
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability.
CORO1C expression is associated with poor survival rates in gastric cancer and promotes metastasis in vitro.
A miR-567-PIK3AP1-PI3K/AKT-c-Myc feedback loop regulates tumour growth and chemoresistance in gastric cancer.
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation.
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
miR-629-5p promotes growth and metastasis of hepatocellular carcinoma by activating β-catenin.
Thyroid hormone (T(3)) is involved in inhibiting the proliferation of newborn calf Sertoli cells via the PI3K/Akt signaling pathway in vitro.
SND1 promotes the proliferation of osteosarcoma cells by upregulating COX‑2/PGE2 expression via activation of NF‑κB.
Nuclear factor I/B promotes colorectal cancer cell proliferation, epithelial-mesenchymal transition and 5-fluorouracil resistance.
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Regulation of Cell Cycle Regulatory Proteins by MicroRNAs in Uterine Leiomyoma.
Down-regulation of miR-1181 indicates a dismal prognosis for nasopharyngeal carcinoma and promoted cell proliferation and metastasis by modulating Wnt/β-catenin signaling.
Overexpression of SIRT4 inhibits the proliferation of gastric cancer cells through cell cycle arrest.
JTC-801 inhibits the proliferation and metastasis of the Hep G2 hepatoblastoma cell line by regulating the phosphatidylinositol 3-kinase/protein kinase B signalling pathway.
Retracted: Inhibition of microRNA-940 suppresses the migration and invasion of human osteosarcoma cells through the secreted frizzled-related protein 1-mediated Wnt/β-catenin signaling pathway.
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway.
CircCDYL inhibits the expression of C-MYC to suppress cell growth and migration in bladder cancer.
Histone deacetylases inhibitor MS-275 suppresses human esophageal squamous cell carcinoma cell growth and progression via the PI3K/Akt/mTOR pathway.
HOXC13-AS promotes breast cancer cell growth through regulating miR-497-5p/PTEN axis.
MiR-6838-5p suppresses cell metastasis and the EMT process in triple-negative breast cancer by targeting WNT3A to inhibit the Wnt pathway.
MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
LncRNA AC007271.3 promotes cell proliferation, invasion, migration and inhibits cell apoptosis of OSCC via the Wnt/β-catenin signaling pathway.
Paper/polymer composited microfluidic platform for screening cell viability and protein expression under a chemical gradient environment.
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment.
Angiotensin blockade attenuates diabetic nephropathy in hypogonadal adult male rats.
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
(-)-Epicatechin mitigates radiation-induced intestinal injury and promotes intestinal regeneration via suppressing oxidative stress.
RING finger protein 10 is a potential drug target for diabetic vascular complications.
Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway.
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer.
Enhanced expression of circular RNA hsa_circ_000984 promotes cells proliferation and metastasis in non-small cell lung cancer by modulating Wnt/β-catenin pathway.
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo.
Poly(ADP-ribose) Polymerase-1 is required for hepatocyte proliferation and liver regeneration in mice.
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
Exogenous biological renal support ameliorates renal pathology after ischemia reperfusion injury in elderly mice.
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
The Long Noncoding RNA 150Rik Promotes Mesangial Cell Proliferation via miR-451/IGF1R/p38 MAPK Signaling in Diabetic Nephropathy.
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
CircRNA8924 Promotes Cervical Cancer Cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8.
Bushenshugan Formula Attenuates the Development of Lung Cancer by Inhibiting Epithelial-Mesenchymal Transition.
Down-regulation of long non-coding RNA ITGB2-AS1 inhibits osteosarcoma proliferation and metastasis by repressing Wnt/β-catenin signalling and predicts favourable prognosis.
Overexpression of Annexin A2 Receptor Inhibits Neovascularization via the Promotion of Krüppel-Like Transcription Factor 2.
SKA3 promotes cell proliferation and migration in cervical cancer by activating the PI3K/Akt signaling pathway.
VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2.
The protective role of human ghrelin in sepsis: Restoration of CD4 T cell proliferation.
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling.
LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
miR-25 Promotes Melanoma Progression by regulating RNA binding motif protein 47.
Knockdown of Sox2 Inhibits OS Cells Invasion and Migration via Modulating Wnt/β-Catenin Signaling Pathway.
Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis.
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
MiR-1301-3p inhibits human breast cancer cell proliferation by regulating cell cycle progression and apoptosis through directly targeting ICT1.
Aclidinium inhibits proliferation and metastasis of ovarian cancer SKOV3 cells via downregulating PI3K/AKT/mTOR signaling pathway.
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Differential anticancer activities of arsenic trioxide on head and neck cancer cells with different human papillomavirus status.
Mitochondrial ATAD3A regulates milk biosynthesis and proliferation of mammary epithelial cells from dairy cow via the mTOR pathway.
Inhibitory effects of aesculetin on the proliferation of colon cancer cells by the Wnt/β-catenin signaling pathway.
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
The NK1 receptor antagonist NKP608 inhibits proliferation of human colorectal cancer cells via Wnt signaling pathway.
MicroRNA-1247 inhibits cell proliferation by directly targeting ZNF346 in childhood neuroblastoma.
HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer.
CCN1/Cyr61 enhances the function of hepatic stellate cells in promoting the progression of hepatocellular carcinoma.
Actin-capping protein CapG is associated with prognosis, proliferation and metastasis in human glioma.
Annexin A2 positively regulates milk synthesis and proliferation of bovine mammary epithelial cells through the mTOR signaling pathway.
Incorporation of Cerium Oxide into Hydroxyapatite Coating Protects Bone Marrow Stromal Cells Against H(2)O(2)-Induced Inhibition of Osteogenic Differentiation.
Cellular response to persistent foot-and-mouth disease virus infection is linked to specific types of alterations in the host cell transcriptome.
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
MicroRNA-384 inhibits the progression of breast cancer by targeting ACVR1.
Curcumin-Loaded Solid Lipid Nanoparticles Enhanced Anticancer Efficiency in Breast Cancer.
NF-κB and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.
LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial-mesenchymal transition through the Notch1 signaling pathway.
DEAD-box helicase 6 (DDX6) is a new negative regulator for milk synthesis and proliferation of bovine mammary epithelial cells.
High expression of TMEM40 is associated with the malignant behavior and tumorigenesis in bladder cancer.
Involvement of mitochondrial fission in calcium sensing receptor-mediated vascular smooth muscle cells proliferation during hypertension.
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Vascular peroxidase 1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation, apoptosis resistance and migration.
YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury.
PTBP3 splicing factor promotes hepatocellular carcinoma by destroying the splicing balance of NEAT1 and pre-miR-612.
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway.
Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
Resveratrol inhibits the growth of gastric cancer via the Wnt/β-catenin pathway.
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
Telmisartan inhibits NSCLC A549 cell proliferation and migration by regulating the PI3K/AKT signaling pathway.
Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade.
MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation.
Androgen Receptor Is Inactivated and Degraded in Bladder Cancer Cells by Phenyl Glucosamine via miR-449a Restoration.
Anticancer effect of PP31J isolated from Physalis pubescens L. in human cervical carcinoma cells.
Histone deacetylase inhibitor NaBut suppresses cell proliferation and induces apoptosis by targeting p21 in multiple myeloma.
Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer.
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Therapy Effects of Wogonin on Ovarian Cancer Cells.
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
CDKL1 promotes tumor proliferation and invasion in colorectal cancer.
Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer.
Mono-ADP-ribosylation of histone 3 at arginine-117 promotes proliferation through its interaction with P300.
Salusin-β mediates high glucose-induced endothelial injury via disruption of AMPK signaling pathway.
Knockdown of tripartite motif-59 inhibits the malignant processes in human colorectal cancer cells.
Knockdown of Immature Colon Carcinoma Transcript 1 Inhibits Proliferation and Promotes Apoptosis of Non-Small Cell Lung Cancer Cells.
EDIL3 knockdown inhibits retinal angiogenesis through the induction of cell cycle arrest in vitro.
Downregulation of Cohesin Loading Factor Nipped-B-Like Protein (NIPBL) Induces Cell Cycle Arrest, Apoptosis, and Autophagy of Breast Cancer Cell Lines.
Twinfilin 1 enhances milk bio-synthesis and proliferation of bovine mammary epithelial cells via the mTOR signaling pathway.
Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma.
DLEU1 contributes to ovarian carcinoma tumourigenesis and development by interacting with miR-490-3p and altering CDK1 expression.
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Fascaplysin inhibit ovarian cancer cell proliferation and metastasis through inhibiting CDK4.
MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication.
(-)-Curine induces cell cycle arrest and cell death in hepatocellular carcinoma cells in a p53-independent way.
The transcription factor FOXA1 induces epithelial ovarian cancer tumorigenesis and progression.
The soy-derived peptide Vglycin inhibits the growth of colon cancer cells in vitro and in vivo.
High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling.
Involvement of the activation of Nrf2/HO-1, p38 MAPK signaling pathways and endoplasmic reticulum stress in furazolidone induced cytotoxicity and S phase arrest in human hepatocyte L02 cells: modulation of curcumin.
miR-491-5p, mediated by Foxi1, functions as a tumor suppressor by targeting Wnt3a/β-catenin signaling in the development of gastric cancer.
Correlations between TBL1XR1 and recurrence of colorectal cancer.
Methylation of SLFN11 is a marker of poor prognosis and cisplatin resistance in colorectal cancer.
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
ω-3 free fatty acids and all-trans retinoic acid synergistically induce growth inhibition of three subtypes of breast cancer cell lines.
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Methylation of DACT2 promotes breast cancer development by activating Wnt signaling.
Effects of digoxin on cell cycle, apoptosis and NF-κB pathway in Burkitt's lymphoma cells and animal model.
Estrogen receptor-α36 is involved in icaritin induced growth inhibition of triple-negative breast cancer cells.
Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.
Dalbinol, a rotenoid from Amorpha fruticosa L., exerts anti-proliferative activity by facilitating β-catenin degradation in hepatocellular carcinoma cells.
Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.
Galangin suppresses human osteosarcoma cells: An exploration of its underlying mechanism.
H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells.
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Circular RNA 0000096 affects cell growth and migration in gastric cancer.
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway.
Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells.
TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway.
Rhodium (II) complex with 2-benzoylpyridine, a novel potential chemotherapeutic drug, induces cell cycle arrest and apoptosis in HepG2 cells.
MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling.
GRP78 positively regulates estrogen‑stimulated cell growth mediated by ER‑α36 in gastric cancer cells.
Knockdown of Rhotekin 2 expression suppresses proliferation and induces apoptosis in colon cancer cells.
Shrimp miR-34 from Shrimp Stress Response to Virus Infection Suppresses Tumorigenesis of Breast Cancer.
Effects of high-intensity focused ultrasound on cisplatin-resistant human lung adenocarcinoma in vitro and in vivo.
Downregulation of USP32 inhibits cell proliferation, migration and invasion in human small cell lung cancer.
Fangchinoline suppresses the proliferation, invasion and tumorigenesis of human osteosarcoma cells through the inhibition of PI3K and downstream signaling pathways.
Efficient expression of stable recombinant human insulin-like growth factor-1 fusion with human serum albumin in Chinese hamster ovary cells.
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
GOLPH3 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in epithelial ovarian cancer.
The role of MIF, cyclinD1 and ERK in the development of pulmonary hypertension in broilers.
Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis.
The Antitumor Effect of DYC-279 on Human Hepatocellular Carcinoma HepG2 Cells.
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer.
Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib.
Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway.
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Knockdown of USP39 induces cell cycle arrest and apoptosis in melanoma.
Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma.
Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance.
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
LSD1 is Required for Hair Cell Regeneration in Zebrafish.
The effects of the 5-HT2A receptor antagonist sarpogrelate hydrochloride on chronic hypoxic pulmonary hypertension in rats.
The AhR is involved in the regulation of LoVo cell proliferation through cell cycle-associated proteins.
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Down-regulation of dihydrofolate reductase inhibits the growth of endothelial EA.hy926 cell through induction of G1 cell cycle arrest via up-regulating p53 and p21(waf1/cip1) expression.
miR-194 inhibits the proliferation, invasion, migration, and enhances the chemosensitivity of non-small cell lung cancer cells by targeting forkhead box A1 protein.
MicroRNA-655-3p functions as a tumor suppressor by regulating ADAM10 and β-catenin pathway in Hepatocellular Carcinoma.
The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR.
Latcripin-13 domain induces apoptosis and cell cycle arrest at the G1 phase in human lung carcinoma A549 cells.
High Expression of XRCC6 Promotes Human Osteosarcoma Cell Proliferation through the β-Catenin/Wnt Signaling Pathway and Is Associated with Poor Prognosis.
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway.
GalNAc-T4 putatively modulates the estrogen regulatory network through FOXA1 glycosylation in human breast cancer cells.
Keratinocyte Growth Factor Regulation of Aryl Hydrocarbon Receptor Activation in Colorectal Cancer Cells.
miRNA-149* promotes cell proliferation and suppresses apoptosis by mediating JunB in T-cell acute lymphoblastic leukemia.
MicroRNA-101 targets von Hippel-Lindau tumor suppressor (VHL) to induce HIF1α mediated apoptosis and cell cycle arrest in normoxia condition.
Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma.
Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling.
Paper-based microreactor array for rapid screening of cell signaling cascades.
PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway.
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways.
RNA interference of Biot2 induces G1 phase arrest and apoptosis in mouse colorectal cancer cell line.
Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway.
Pemetrexed induces G1 phase arrest and apoptosis through inhibiting Akt activation in human non small lung cancer cell line A549.
Lentivirus-mediated gene silencing of NOB1 suppresses non-small cell lung cancer cell proliferation.
Doxorubicin-poly (ethylene glycol)-alendronate self-assembled micelles for targeted therapy of bone metastatic cancer.
Low SFRP1 Expression Correlates with Poor Prognosis and Promotes Cell Invasion by Activating the Wnt/β-Catenin Signaling Pathway in NPC.
miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells.
Quercetin reverses experimental pulmonary arterial hypertension by modulating the TrkA pathway.
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
MicroRNA-490-3P targets CDK1 and inhibits ovarian epithelial carcinoma tumorigenesis and progression.
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Knockdown of ANLN by lentivirus inhibits cell growth and migration in human breast cancer.
Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins.
Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.
Capsaicin causes inactivation and degradation of the androgen receptor by inducing the restoration of miR-449a in prostate cancer.
STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer.
Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation.
Gemcitabine resistance in breast cancer cells regulated by PI3K/AKT-mediated cellular proliferation exerts negative feedback via the MEK/MAPK and mTOR pathways.
USP22 promotes the G1/S phase transition by upregulating FoxM1 expression via β-catenin nuclear localization and is associated with poor prognosis in stage II pancreatic ductal adenocarcinoma.
Knockdown of ZFX suppresses renal carcinoma cell growth and induces apoptosis.
Eupolyphaga sinensis Walker inhibits human chronic myeloid leukemia cell K562 growth by inducing G2-M phase cell cycle arrest and targeting EGFR signaling pathway and in S180 tumor-bearing mice.
Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells.
SOX2 regulates apoptosis through MAP4K4-survivin signaling pathway in human lung cancer cells.
Downregulated protein O-fucosyl transferase 1 (Pofut1) expression exerts antiproliferative and antiadhesive effects on hepatocytes by inhibiting Notch signalling.
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma.
MiR-612 suppresses the stemness of liver cancer via Wnt/β-catenin signaling.
Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom.
Hepatitis B viral RNA directly mediates down-regulation of the tumor suppressor microRNA miR-15a/miR-16-1 in hepatocytes.
C1orf61 acts as a tumor activator in human hepatocellular carcinoma and is associated with tumorigenesis and metastasis.
Brucine, an effective natural compound derived from nux-vomica, induces G1 phase arrest and apoptosis in LoVo cells.
Caveolin-1 knockdown is associated with the metastasis and proliferation of human lung cancer cell line NCI-H460.
Hu K, Xie L, Wu W, Zhang J, Li Y, He J, Zhang Y, Lu D, Koeffler HP, Lin L, Yin D
International journal of biological sciences 2024;20(8):3140-3155
International journal of biological sciences 2024;20(8):3140-3155
CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis.
Zhang P, Yang Q, Chen X, Chen X, Wang Q, Chen K, An Y, Jiang K, Sun F
Journal of Cancer 2024;15(3):858-870
Journal of Cancer 2024;15(3):858-870
Brucine Suppresses Malignant Progression of Prostate Cancer by Decreasing Sarcosine Accumulation via Downregulation of GNMT in the Glycine/sarcosine Metabolic Pathway.
Miao L, Liu Y, Chen W, Gao C, Zhang Y, Wei J, Cao X
Cell biochemistry and biophysics 2024 Sep;82(3):2373-2385
Cell biochemistry and biophysics 2024 Sep;82(3):2373-2385
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.
Zhang Q, Li Y, Zhu Q, Xie T, Xiao Y, Zhang F, Li N, Deng K, Xin H, Huang X
Cell death & disease 2024 May 22;15(5):355
Cell death & disease 2024 May 22;15(5):355
IDH1 mutation produces R-2-hydroxyglutarate (R-2HG) and induces mir-182-5p expression to regulate cell cycle and tumor formation in glioma.
Zhao H, Meng L, Du P, Liao X, Mo X, Gong M, Chen J, Liao Y
Biological research 2024 May 17;57(1):30
Biological research 2024 May 17;57(1):30
Combined SET7/9 and CDK4 inhibition act synergistically against osteosarcoma.
Shi Y, Wang Z, Shao Y, Guang Q, Zhang J, Liu B, Wu C, Wang Y, Sui P
Biochemical and biophysical research communications 2024 May 14;708:149808
Biochemical and biophysical research communications 2024 May 14;708:149808
Copper Chaperone Atox1 Protected the Cochlea From Cisplatin by Regulating the Copper Transport Family and Cell Cycle.
Chen X, Xiang W, Li L, Xu K
International journal of toxicology 2024 Mar-Apr;43(2):134-145
International journal of toxicology 2024 Mar-Apr;43(2):134-145
Cynaroside Induces G1 Cell Cycle Arrest by Downregulating Cell Division Cycle 25A in Colorectal Cancer.
Lei S, Cao W, Zeng Z, Wang L, Lan J, Chen T
Molecules (Basel, Switzerland) 2024 Mar 28;29(7)
Molecules (Basel, Switzerland) 2024 Mar 28;29(7)
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
Fei X, Zhu C, Liu P, Liu S, Ren L, Lu R, Hou J, Gao Y, Wang X, Pan Y
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
ART1 knockdown decreases the IL-6-induced proliferation of colorectal cancer cells.
Lin T, Zhang S, Tang Y, Xiao M, Li M, Gong H, Xie H, Wang Y
BMC cancer 2024 Mar 19;24(1):354
BMC cancer 2024 Mar 19;24(1):354
YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia.
Liu Z, Li S, Chen S, Sheng J, Li Z, Lv T, Yu W, Fan Y, Wang J, Liu W, Hu S, Jin J
iScience 2024 Mar 15;27(3):109125
iScience 2024 Mar 15;27(3):109125
CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8 + T cell response.
Cen Q, Chen J, Guo J, Chen M, Wang H, Wu S, Zhang H, Xie X, Li Y
Journal of translational medicine 2024 Mar 14;22(1):278
Journal of translational medicine 2024 Mar 14;22(1):278
β-catenin/TCF4-induced SCUBE3 upregulation promotes ovarian cancer development via HIF-1 signaling pathway.
Shen J, Ma X, Wei Z, Qian Q, Jing A, Ding Y, Geng T, Qin J, Ma L, Chen Y, Ji J, Liu B, Huang J
Molecular and cellular endocrinology 2024 Mar 1;582:112127
Molecular and cellular endocrinology 2024 Mar 1;582:112127
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
Guo Y, Feng Y, Jiang F, Hu L, Shan T, Li H, Liao H, Bao H, Shi H, Si Y
Brain research 2024 Mar 1;1826:148731
Brain research 2024 Mar 1;1826:148731
ZNF862 induces cytostasis and apoptosis via the p21-RB1 and Bcl-xL-Caspase 3 signaling pathways in human gingival fibroblasts.
Zhu Y, Zhao T, Wu Y, Xie S, Sun W, Wu J
Journal of periodontal research 2024 Jun;59(3):599-610
Journal of periodontal research 2024 Jun;59(3):599-610
Bioinspired engineering ADSC nanovesicles thermosensitive hydrogel enhance autophagy of dermal papilla cells for androgenetic alopecia treatment.
Xiong J, Liu Z, Jia L, Sun Y, Guo R, Xi T, Li Z, Wu M, Jiang H, Li Y
Bioactive materials 2024 Jun;36:112-125
Bioactive materials 2024 Jun;36:112-125
Overexpression of FHL1 suppresses papillary thyroid cancer proliferation and progression via inhibiting Wnt/β-catenin pathway.
Chen J, Zeng C, Jin J, Zhang P, Zhang Y, Zhang H, Li Y, Guan H
Endocrine 2024 Jul;85(1):238-249
Endocrine 2024 Jul;85(1):238-249
Melatonin promotes cell cycle progression of neural stem cells subjected to manganese via Nurr1.
Chen N, Zhou H, He B, Peng S, Ding F, Liu QH, Ma Z, Liu W, Xu B
Environmental toxicology 2024 Jul;39(7):3883-3896
Environmental toxicology 2024 Jul;39(7):3883-3896
Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells.
Song Y, Deng M, Qiu Y, Cui Y, Zhang B, Xin J, Feng L, Mu X, Cui J, Li H, Sun Y, Yi W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155592
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155592
SPP1 could be an immunological and prognostic biomarker: From pan-cancer comprehensive analysis to osteosarcoma validation.
Zhang Z, Liu B, Lin Z, Mei L, Chen R, Li Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23783
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23783
let-7g sensitized liver cancer cells to 5-fluorouracil by downregulating ABCC10 expression.
Chen Y, Zhang B, Zhong C, Zhou Y, Xue L, Luo C, Yi L, Gong Q, Long Y
Chemical biology & drug design 2024 Jan;103(1):e14396
Chemical biology & drug design 2024 Jan;103(1):e14396
TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma.
Chen Y, Han Z, Zhang L, Gao C, Wei J, Yang X, Han Y, Li Y, Zhang C, Wei Y, Dong J, Xun W, Sun W, Zhang T, Zhang H, Chen J, Yuan P
Journal of translational medicine 2024 Jan 4;22(1):21
Journal of translational medicine 2024 Jan 4;22(1):21
MiR-199a-5p inhibits dermal papilla cells proliferation by regulating VEGFA expression in cashmere goat.
Zhang T, Zheng Y, Zhang F, Wang X, Du J, Wang X
Gene 2024 Jan 30;893:147901
Gene 2024 Jan 30;893:147901
CHEK2 knockout is a therapeutic target for TP53-mutated hepatocellular carcinoma.
Chen Y, Zhu Z, Wu X, Li H, Guan W, Ren H
Cell death discovery 2024 Jan 19;10(1):37
Cell death discovery 2024 Jan 19;10(1):37
Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.
Shi M, Huang K, Wei J, Wang S, Yang W, Wang H, Li Y
International journal of molecular sciences 2024 Jan 14;25(2)
International journal of molecular sciences 2024 Jan 14;25(2)
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Zhan J, Zhou L, Zhang H, Zhou J, He Y, Hu T, Le Y, Lin Y, Wang J, Yu H, Liu Y, Xiang X
Translational oncology 2024 Feb;40:101843
Translational oncology 2024 Feb;40:101843
Cepharanthine suppresses APC-mutant colorectal cancers by down-regulating the expression of β-catenin.
Su G, Wang D, Yang Q, Kong L, Ju X, Yang Q, Zhu Y, Zhang S, Li Y
Natural products and bioprospecting 2024 Feb 29;14(1):18
Natural products and bioprospecting 2024 Feb 29;14(1):18
Schisandrin B promotes hepatic differentiation from human umbilical cord mesenchymal stem cells.
Jin M, Yi X, Zhu X, Hu W, Wang S, Chen Q, Yang W, Li Y, Li S, Peng Q, Pan M, Gao Y, Xu S, Zhang Y, Zhou S
iScience 2024 Feb 16;27(2):108912
iScience 2024 Feb 16;27(2):108912
ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner.
Zhang C, Yu Z, Yang S, Liu Y, Song J, Mao J, Li M, Zhao Y
Molecular cancer 2024 Feb 14;23(1):33
Molecular cancer 2024 Feb 14;23(1):33
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
Xu J, Wu X, Zhu H, Zhu Y, Du K, Deng X, Wang C
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
Dendrobium nobile active ingredient Dendrobin A against hepatocellular carcinoma via inhibiting nuclear factor kappa-B signaling.
Yu Y, Fan Y, Mei W, Xu X, Chen Y, Zhao Y, Ruan B, Shen Z, Lu Y, Zheng S, Jie W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117013
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117013
Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis.
Li T, Gao S, Wei Y, Wu G, Feng Y, Wang Y, Jiang X, Kuang H, Han W
Journal of pharmaceutical and biomedical analysis 2024 Aug 1;245:116163
Journal of pharmaceutical and biomedical analysis 2024 Aug 1;245:116163
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
Liu Z, Zhao P
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Wang P, Zhang H, Guo K, Liu C, Chen S, Pu B, Chen S, Feng T, Jiao H, Gao C
Oncology letters 2024 Apr;27(4):140
Oncology letters 2024 Apr;27(4):140
Matairesinoside, a novel inhibitor of TMEM16A ion channel, loaded with functional hydrogel for lung cancer treatment.
Wang Z, Geng R, Chen Y, Qin J, Guo S
International journal of biological macromolecules 2024 Apr;264(Pt 2):130618
International journal of biological macromolecules 2024 Apr;264(Pt 2):130618
TuBG1 promotes hepatocellular carcinoma via ATR/P53-apoptosis and cycling pathways.
Zhang Y, Wang ZZ, Han AQ, Yang MY, Zhu LX, Pan FM, Wang Y
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Apr;23(2):195-209
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Apr;23(2):195-209
Cadmium disrupts spermatogenic cell cycle via piRNA-DQ717867/p53 pathway.
Wei J, Dai J, Shi X, Zhao R, Fu G, Li R, Xia C, Zhang L, Zhou T, Wang H, Shi Y
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108554
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108554
Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis.
Liu B, Xian Y, Chen X, Shi Y, Dong J, Yang L, An X, Shen T, Wu W, Ma Y, He Y, Gong W, Peng R, Lin J, Liu N, Guo B, Jiang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307338
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307338
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer.
Han JY, Che N, Mo J, Zhang DF, Liang XH, Dong XY, Zhao XL, Sun BC
BMC cancer 2024 Apr 26;24(1):532
BMC cancer 2024 Apr 26;24(1):532
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
Zhang M, Cai F, Guo J, Liu S, Ma G, Cai M, Zhang R, Deng J
Cell death & disease 2024 Apr 26;15(4):297
Cell death & disease 2024 Apr 26;15(4):297
Peptide Inhibitor Targeting the Extraterminal Domain in BRD4 Potently Suppresses Breast Cancer Both In Vitro and In Vivo.
Huang QX, Fan DM, Zheng ZZ, Ran T, Bai A, Xiao RQ, Hu GS, Liu W
Journal of medicinal chemistry 2024 Apr 25;67(8):6658-6672
Journal of medicinal chemistry 2024 Apr 25;67(8):6658-6672
Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma.
Sun Y, Chen Y, Zhao H, Wang J, Liu Y, Bai J, Hu C, Shang Z
iScience 2024 Apr 19;27(4):109340
iScience 2024 Apr 19;27(4):109340
PRMT6-mediated transcriptional activation of ythdf2 promotes glioblastoma migration, invasion, and emt via the wnt-β-catenin pathway.
Yu P, Xu T, Ma W, Fang X, Bao Y, Xu C, Huang J, Sun Y, Li G
Journal of experimental & clinical cancer research : CR 2024 Apr 18;43(1):116
Journal of experimental & clinical cancer research : CR 2024 Apr 18;43(1):116
The role of miR-222-2p in exosomes secreted by hexavalent chromium-induced premature senescent hepatocytes as a SASP component.
Ma Y, Li S, Ye S, Luo S, Wei L, Su Y, Zeng Y, Shi Y, Bian H, Xiao F
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123535
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123535
Isolation and Cultivation of Vascular Smooth Muscle Cells from the Mouse Circle of Willis.
Chang W, Li Y, Liu F, Zang K, Zhang P, Qu S, Zhao J, Xue J
Journal of vascular research 2023;60(4):234-244
Journal of vascular research 2023;60(4):234-244
NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner.
Zhou Y, Qian W, Li X, Wei W
Oxidative medicine and cellular longevity 2023;2023:7098313
Oxidative medicine and cellular longevity 2023;2023:7098313
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Zhu Y, Sun W, Jiang X, Bai R, Luo Y, Gao Y, Li S, Huang Z, Gong Y, Xie C
PloS one 2023;18(1):e0281132
PloS one 2023;18(1):e0281132
PRMT7 Inhibits the Proliferation and Migration of Gastric Cancer Cells by Suppressing the PI3K/AKT Pathway via PTEN.
Wang X, Xu W, Zhu C, Cheng Y, Qi J
Journal of Cancer 2023;14(15):2833-2844
Journal of Cancer 2023;14(15):2833-2844
HSP105 suppresses the progression of cutaneous squamous cell carcinoma by activating the P53 signaling pathway.
Jia M, Zhou KY, Deng LJ, Fang S
American journal of cancer research 2023;13(7):3013-3026
American journal of cancer research 2023;13(7):3013-3026
Prognostic and therapeutic implications of iron-related cell death pathways in acute myeloid leukemia.
Li T, Lin T, Zhu J, Zhou M, Fan S, Zhou H, Mu Q, Sheng L, Ouyang G
Frontiers in oncology 2023;13:1222098
Frontiers in oncology 2023;13:1222098
Role of UDP-glucose ceramide glucosyltransferase in venous malformation.
Chen S, Wang Y, Kong L, Ji Y, Cui J, Shen W
Frontiers in cell and developmental biology 2023;11:1178045
Frontiers in cell and developmental biology 2023;11:1178045
LINC02870 facilitates SNAIL translation to promote hepatocellular carcinoma progression.
Guo M, Zhuang H, Huang J, Shao X, Bai N, Li M, Niu M, Wei W, Sun L, Li Y, Qiang Z
Molecular and cellular biochemistry 2023 Sep;478(9):1899-1914
Molecular and cellular biochemistry 2023 Sep;478(9):1899-1914
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression.
An X, Wu W, Yang L, Dong J, Liu B, Guo J, Chen J, Guo B, Cao W, Jiang Q
Translational research : the journal of laboratory and clinical medicine 2023 Sep;259:62-71
Translational research : the journal of laboratory and clinical medicine 2023 Sep;259:62-71
CCDC85C suppresses colorectal cancer cells proliferation and metastasis through activating GSK-3β and promoting β-catenin degradation.
Hu W, Shen J, Tao Y, Dong D, Lu S, Li L, Sun D, Fan M, Xu C, Shen W, Yu C, Cheng H
Cellular signalling 2023 Sep;109:110799
Cellular signalling 2023 Sep;109:110799
SUMO-Activating Enzyme Subunit 1 Is Associated with Poor Prognosis, Tumor Progression, and Radio-Resistance in Colorectal Cancer.
Wu YJ, Huang ST, Chang YH, Lin SY, Lin WL, Chen YJ, Chien ST
Current issues in molecular biology 2023 Sep 30;45(10):8013-8026
Current issues in molecular biology 2023 Sep 30;45(10):8013-8026
Ar-turmerone inhibits the proliferation and mobility of glioma by downregulating cathepsin B.
Cao W, Chen X, Xiao C, Lin D, Li Y, Luo S, Zeng Z, Sun B, Lei S
Aging 2023 Sep 26;15(18):9377-9390
Aging 2023 Sep 26;15(18):9377-9390
Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.
Guo Z, Guo L
Experimental cell research 2023 Sep 15;430(2):113714
Experimental cell research 2023 Sep 15;430(2):113714
DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.
Wen R, Zhou L, Jiang S, Fan H, Zheng K, Yu Y, Gao X, Hao L, Lou Z, Yu G, Yang F, Zhang W
International journal of radiation oncology, biology, physics 2023 Sep 1;117(1):198-210
International journal of radiation oncology, biology, physics 2023 Sep 1;117(1):198-210
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Wu Y, Chen W, Zhang B, Liu H
Tissue & cell 2023 Oct;84:102193
Tissue & cell 2023 Oct;84:102193
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
Yao X, Liu H, Wang Z, Lu F, Chen W, Feng Q, Miao Y, Zhang J, Wang Y, Chen Y, Xue L, Liu Y, Chen L, Zhang Q
Oncogene 2023 Oct;42(43):3206-3218
Oncogene 2023 Oct;42(43):3206-3218
MTHFD2 promotes PD-L1 expression via activation of the JAK/STAT signalling pathway in bladder cancer.
Li L, Zhang Y, Hu W, Zou F, Ning J, Rao T, Ruan Y, Yu W, Cheng F
Journal of cellular and molecular medicine 2023 Oct;27(19):2922-2936
Journal of cellular and molecular medicine 2023 Oct;27(19):2922-2936
Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.
Yin J, Hu T, Xu L, Zhang L, Zhu J, Ye Y, Pang Z
International immunopharmacology 2023 Oct;123:110763
International immunopharmacology 2023 Oct;123:110763
Role of Nucleobindin-2 in the Clinical Pathogenesis and Treatment Resistance of Glioblastoma.
Lin IC, Chang CH, Chong YB, Kuo SH, Cheng YW, Lieu AS, Tseng TT, Lin CJ, Tsai HP, Kwan AL
Cells 2023 Oct 9;12(19)
Cells 2023 Oct 9;12(19)
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
Zhao S, Li Y, Li G, Ye J, Wang R, Zhang X, Li F, Gao C, Li J, Jiang J, Mi Y
European journal of pharmacology 2023 Oct 15;957:176004
European journal of pharmacology 2023 Oct 15;957:176004
A pan-cancer analysis of the role of HOXD1, HOXD3, and HOXD4 and validation in renal cell carcinoma.
Wang L, Wang X, Sun H, Wang W, Cao L
Aging 2023 Oct 12;15(19):10746-10766
Aging 2023 Oct 12;15(19):10746-10766
IGF2BP2 acts as a m(6)A modification regulator in laryngeal squamous cell carcinoma through facilitating CDK6 mRNA stabilization.
Tang X, Tang Q, Li S, Li M, Yang T
Cell death discovery 2023 Oct 10;9(1):371
Cell death discovery 2023 Oct 10;9(1):371
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice.
Jiang PY, Lin S, Liu JR, Liu Y, Zheng LM, Hong Q, Fan YJ, Xu DX, Chen YH
Archives of toxicology 2023 Nov;97(11):2929-2941
Archives of toxicology 2023 Nov;97(11):2929-2941
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Ma H, Jiang S, Yuan Y, Li J, Li Y, Lv Y, Du T, Guan J, Jiang X, Tian L, Zheng Q, Yang L, Li Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
IL-7 promotes CD19-directed CAR-T cells proliferation through miRNA-98-5p by targeting CDKN1A.
Yang LR, Li L, Meng MY, Li TT, Zhao YY, Yang SL, Gao H, Tang WW, Yang Y, Yang LL, Wang WJ, Liao LW, Hou ZL
International immunopharmacology 2023 Nov;124(Pt B):110974
International immunopharmacology 2023 Nov;124(Pt B):110974
A large-scale transcriptional analysis reveals herb-derived ginsenoside F2 suppressing hepatocellular carcinoma via inhibiting STAT3.
Tan X, Ma X, Dai Y, An J, Yu X, Li S, Liao Y, Pei T, Tang Y, Gui Y, Zhou S, Guo D, Deng Y, Hu K, Wang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155031
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155031
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
Zhang Y, Fan Y, Hu H, Zhang X, Wang Z, Wu Z, Wang L, Yu X, Song X, Xiang P, Zhang X, Wang T, Tan S, Li C, Gao L, Liang X, Li S, Li N, Yue X, Ma C
Nature communications 2023 Nov 18;14(1):7527
Nature communications 2023 Nov 18;14(1):7527
Tripartite motif 31 drives gastric cancer cell proliferation and invasion through activating the Wnt/β-catenin pathway by regulating Axin1 protein stability.
Feng Q, Nie F, Gan L, Wei X, Liu P, Liu H, Zhang K, Fang Z, Wang H, Fang N
Scientific reports 2023 Nov 16;13(1):20099
Scientific reports 2023 Nov 16;13(1):20099
GAD1-mediated GABA elicits aggressive characteristics of human oral cancer cells.
Dou Z, Li M, Shen Z, Jiang H, Pang X, Li T, Liang X, Tang Y
Biochemical and biophysical research communications 2023 Nov 12;681:80-89
Biochemical and biophysical research communications 2023 Nov 12;681:80-89
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
Wang S, Zhang X, Lei H, Song L, Huang Y, Kang T, Zhang M, Wang N, Yang P, Feng S, Wang J, Bai R, Wang N, Wang W, Zheng Y
Molecular carcinogenesis 2023 May;62(5):613-627
Molecular carcinogenesis 2023 May;62(5):613-627
Targeting diacylglycerol kinase α impairs lung tumorigenesis by inhibiting cyclin D3.
Zhou D, Liu T, Rao X, Jie X, Chen Y, Wu Z, Deng H, Zhang D, Wang J, Wu G
Thoracic cancer 2023 May;14(13):1179-1191
Thoracic cancer 2023 May;14(13):1179-1191
The High Level of RANKL Improves IκB/p65/Cyclin D1 Expression and Decreases p-Stat5 Expression in Firm Udder of Dairy Goats.
Gao Z, Shao D, Zhao C, Liu H, Zhao X, Wei Q, Ma B
International journal of molecular sciences 2023 May 16;24(10)
International journal of molecular sciences 2023 May 16;24(10)
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Li Z, Chen C, Yong H, Jiang L, Wang P, Meng S, Chu S, Li Z, Guo Q, Zheng J, Bai J, Li H
Cell death & disease 2023 May 12;14(5):322
Cell death & disease 2023 May 12;14(5):322
Microtubule-associated protein 4 promotes epithelial mesenchymal transition in hepatocellular cancer cells via regulating GSK3β/β-catenin pathway.
Hu P, Zong B, Chen Q, Shao R, Chen M, Yang Y, Shao G
Heliyon 2023 Mar;9(3):e14309
Heliyon 2023 Mar;9(3):e14309
Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity.
Zhao H, Tang S, Tao Q, Ming T, Lei J, Liang Y, Peng Y, Wang M, Liu M, Yang H, Ren S, Xu H
Journal of agricultural and food chemistry 2023 Mar 8;71(9):3981-3993
Journal of agricultural and food chemistry 2023 Mar 8;71(9):3981-3993
The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury.
Chen Z, He S, Lian S, Shen Y, Jiang W, Zhou L, Zhou L, Zhang X
Bioscience reports 2023 Mar 31;43(3)
Bioscience reports 2023 Mar 31;43(3)
Pan-cancer analysis of PCAT6 and its effect on oesophageal squamous cell carcinoma cell proliferation and migration.
Luo Q, Kuang Y, Tao X, Zhu X, Zhao X, Lu G, Zhang W, Sun E, Chen B
Medical oncology (Northwood, London, England) 2023 Mar 22;40(4):125
Medical oncology (Northwood, London, England) 2023 Mar 22;40(4):125
Human umbilical cord mesenchymal stem cells conditioned medium exerts anti-tumor effects on KGN cells in a cell density-dependent manner through activation of the Hippo pathway.
Wan W, Miao Y, Niu Y, Zhu K, Ma Y, Pan M, Ma B, Wei Q
Stem cell research & therapy 2023 Mar 20;14(1):46
Stem cell research & therapy 2023 Mar 20;14(1):46
Ursolic acid nanoparticles for glioblastoma therapy.
Li Y, Zhao L, Zhao Q, Zhou Y, Zhou L, Song P, Liu B, Chen Q, Deng G
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102684
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102684
MicroRNA-137 inhibits pituitary prolactinoma proliferation by targeting AKT2.
Xu Q, Yu ZX, Xie YL, Bai L, Liang SR, Ji QH, Zhou J
Journal of endocrinological investigation 2023 Jun;46(6):1145-1154
Journal of endocrinological investigation 2023 Jun;46(6):1145-1154
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway.
Sun Y, Weng J, Chen X, Ma S, Zhang Y, Zhang F, Zhang Z, Wang F, Shao J, Zheng S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114653
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114653
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
Yi Q, Zhao Y, Xia R, Wei Q, Chao F, Zhang R, Bian P, Lv L
Cell death discovery 2023 Jun 26;9(1):191
Cell death discovery 2023 Jun 26;9(1):191
HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
Ma H, Qi G, Han F, Gai P, Peng J, Kong B
Cell communication and signaling : CCS 2023 Jun 16;21(1):144
Cell communication and signaling : CCS 2023 Jun 16;21(1):144
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma.
Miao Y, Wang X, Lai Y, Huang Y, Yin H, Meng X, Liu H, Hou R, Lin W, Zhang X, Zhang X, Chai BC, Zhang F, Guo L, Yang S
International journal of oncology 2023 Jul;63(1)
International journal of oncology 2023 Jul;63(1)
eIF3a sustains non-small cell lung cancer stem cell-like properties by promoting YY1-mediated transcriptional activation of β-catenin.
Zheng JY, Zhu T, Zhuo W, Mao XY, Yin JY, Li X, He YJ, Zhang W, Liu C, Liu ZQ
Biochemical pharmacology 2023 Jul;213:115616
Biochemical pharmacology 2023 Jul;213:115616
Ethyl acetate extract of Antenoron Filiforme inhibits the proliferation of triple negative breast cancer cells via suppressing Skp2/p21 signaling axis.
Liao Y, Li S, An J, Yu X, Tan X, Gui Y, Wang Y, Huang L, Zhou S, Wang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154856
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154856
Targeting CDK12 obviates the malignant phenotypes of colorectal cancer through the Wnt/β-catenin signaling pathway.
Liu S, Wu J, Lu X, Guo C, Zheng Q, Wang Y, Hu Q, Bian S, Luo L, Cheng Q, Liu Z, Dai W
Experimental cell research 2023 Jul 1;428(1):113613
Experimental cell research 2023 Jul 1;428(1):113613
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Chen W, Yu H, Sun C, Dong M, Zhao N, Wang Y, Yu K, Zhang J, Xu N, Liu W
Toxicology letters 2023 Jul 1;383:177-191
Toxicology letters 2023 Jul 1;383:177-191
ZYY-B-2, a novel ALK inhibitor, overcomes resistance to ceritinib by inhibiting P-gp function and induces apoptosis through mitochondrial pathway in ceritinib-resistant H2228 cells.
Gao Y, Liu T, Liu J, Yang Y, Sun K, Li Z, Zhai X, Zuo D
Chemico-biological interactions 2023 Jul 1;379:110516
Chemico-biological interactions 2023 Jul 1;379:110516
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
Ye Z, Xia Y, Li L, Li B, Chen W, Han S, Zhou X, Chen L, Yu W, Ruan Y, Cheng F
Translational oncology 2023 Jan;27:101578
Translational oncology 2023 Jan;27:101578
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
Zhao D, Gao Y, Su Y, Zhou Y, Yang T, Li Y, Wang Y, Sun Y, Chen L, Zhang F, Zhang Z, Wang F, Shao J, Zheng S
Pharmacological research 2023 Jan;187:106590
Pharmacological research 2023 Jan;187:106590
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Liu H, Yu L, Ding Y, Peng M, Deng Y
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
Yin W, Fu X, Chang W, Han L, Meng J, Cao A, Ren X, Fan Z, Zhou S
The Journal of pharmacy and pharmacology 2023 Jan 31;75(1):87-97
The Journal of pharmacy and pharmacology 2023 Jan 31;75(1):87-97
Analysis of Promoter Methylation of the Bovine FOXO1 Gene and Its Effect on Proliferation and Differentiation of Myoblasts.
Shi P, Ruan Y, Liu W, Sun J, Xu J, Xu H
Animals : an open access journal from MDPI 2023 Jan 16;13(2)
Animals : an open access journal from MDPI 2023 Jan 16;13(2)
Triptonide inhibits growth and metastasis in HCC by suppressing EGFR/PI3K/AKT signaling.
Zhang H, Mao Y, Zou X, Niu J, Jiang J, Chen X, Zhu M, Yang X, Dong T
Neoplasma 2023 Feb;70(1):94-102
Neoplasma 2023 Feb;70(1):94-102
Effects of the CDC10 (Septin 7) Gene on the Proliferation and Differentiation of Bovine Intramuscular Preadipocyte and 3T3-L1 Cells.
Cheng Z, Li X, Bao S, Yamada T, Cao G, Liu J, Chen A, Tong B
Animals : an open access journal from MDPI 2023 Feb 9;13(4)
Animals : an open access journal from MDPI 2023 Feb 9;13(4)
Krüppel-like Factor 7 inhibits proliferation and migration of pulmonary smooth muscle cells via p21 activation.
Zeng Z, Zhou X, Zhu Y, Huang X, Tong X, Liu J, Zhang T, Wu W
European journal of pharmacology 2023 Feb 5;940:175473
European journal of pharmacology 2023 Feb 5;940:175473
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening.
Deng L, Yang L, Zhu S, Li M, Wang Y, Cao X, Wang Q, Guo L
Cell death discovery 2023 Feb 2;9(1):40
Cell death discovery 2023 Feb 2;9(1):40
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Zhou C, Zhu X, Liu N, Dong X, Zhang X, Huang H, Tang Y, Liu S, Hu M, Wang M, Deng X, Li S, Zhang R, Huang Y, Lyu H, Xiao S, Luo S, Ali DW, Michalak M, Chen XZ, Wang Z, Tang J
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
ANXA3, associated with YAP1 regulation, participates in the proliferation and chemoresistance of cervical cancer cells.
Huang J, Wei W, Kang F, Tan S, Li Y, Lu X, Wang N
Genes & genomics 2023 Dec;45(12):1575-1586
Genes & genomics 2023 Dec;45(12):1575-1586
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
Bai Y, Zhou L, Zhang C, Guo M, Xia L, Tang Z, Liu Y, Deng S
Oncogene 2023 Dec;42(49):3605-3618
Oncogene 2023 Dec;42(49):3605-3618
Effects of dietary folic acid supplementation on lactation performance and mammary epithelial cell development of dairy cows and its regulatory mechanism.
Zhang J, Liu YP, Bu LJ, Liu Q, Pei CX, Huo WJ
Animal biotechnology 2023 Dec;34(8):3796-3807
Animal biotechnology 2023 Dec;34(8):3796-3807
Exogenous H(2)S alleviates senescence of glomerular mesangial cells through up-regulating mitophagy by activation of AMPK-ULK1-PINK1-parkin pathway in mice.
E Y, Lin Y, Yan G, Yang J, Jiao L, Wu R, Yan Q, Chen Y, Chen Y, Yan X, Li H
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119568
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119568
NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis.
Peng Y, Zhang Y, Luo M, Pan Y, Zhou R, Yan YN, Yi T, Luo F, Wang B, Wang L, Ran C, Wang H
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119525
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119525
TC2N Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Targeting the Wnt/β-Catenin Signaling Pathway.
Lou YX, Gu J, Zhu L, Sun SQ, Hao XL, Chen JP, Han F, Wang DD, Jiang X, Liu JY
Laboratory investigation; a journal of technical methods and pathology 2023 Dec;103(12):100260
Laboratory investigation; a journal of technical methods and pathology 2023 Dec;103(12):100260
LINC00921 reduces lung cancer radiosensitivity by destabilizing NUDT21 and driving aberrant MED23 alternative polyadenylation.
Zhang N, Liu X, Huang L, Zeng J, Ma C, Han L, Li W, Yu J, Yang M
Cell reports 2023 Dec 26;42(12):113479
Cell reports 2023 Dec 26;42(12):113479
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Bao H, Peng Z, Cheng X, Jian C, Li X, Shi Y, Zhu W, Hu Y, Jiang M, Song J, Fang F, Chen J, Shu X
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Aberrant epithelial cell interaction promotes esophageal squamous-cell carcinoma development and progression.
Chen L, Zhu S, Liu T, Zhao X, Xiang T, Hu X, Wu C, Lin D
Signal transduction and targeted therapy 2023 Dec 15;8(1):453
Signal transduction and targeted therapy 2023 Dec 15;8(1):453
CD56 polysialylation promotes the tumorigenesis and progression via the Hedgehog and Wnt/β-catenin signaling pathways in clear cell renal cell carcinoma.
Jian Y, Zhang L, Gong L, Ding M, Sun X, Yu X, Lv S, Li J, Yang D, Wang S
Cancer cell international 2023 Dec 12;23(1):319
Cancer cell international 2023 Dec 12;23(1):319
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer.
Tian W, Tang Y, Luo Y, Xie J, Zheng S, Zou Y, Huang X, Wu L, Zhang J, Sun Y, Tang H, Du W, Li X, Xie X
Cell death & disease 2023 Dec 1;14(12):790
Cell death & disease 2023 Dec 1;14(12):790
Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.
Zhang X, Wu N, Huang H, Li S, Liu S, Zhang R, Huang Y, Lyu H, Xiao S, Ali DW, Michalak M, Chen XZ, Zhou C, Tang J
Oncogene 2023 Aug;42(32):2439-2455
Oncogene 2023 Aug;42(32):2439-2455
Histone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia.
Wang H, Qiu Y, Zhang H, Chang N, Hu Y, Chen J, Hu R, Liao P, Li Z, Yang Y, Cen Q, Ding X, Li M, Xie X, Li Y
Cell death & disease 2023 Aug 4;14(8):498
Cell death & disease 2023 Aug 4;14(8):498
High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.
Chen YT, Chung CL, Cheng YW, Lin CJ, Tseng TT, Hsu SS, Tsai HP, Kwan AL
International journal of molecular sciences 2023 Aug 29;24(17)
International journal of molecular sciences 2023 Aug 29;24(17)
Knockdown of KDM5B Leads to DNA Damage and Cell Cycle Arrest in Granulosa Cells via MTF1.
Yang Y, Cai Y, Guo J, Dai K, Liu L, Chen Z, Wang F, Deng M
Current issues in molecular biology 2023 Apr 7;45(4):3219-3237
Current issues in molecular biology 2023 Apr 7;45(4):3219-3237
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer.
Yang H, Pu L, Li R, Zhu R
Journal of gastrointestinal oncology 2023 Apr 29;14(2):900-912
Journal of gastrointestinal oncology 2023 Apr 29;14(2):900-912
8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells.
Zhang D, Fu Y, Liu Y, Wu Y, Chen J, Zhang L, Wang R, Chen Z, Liu T
International journal of molecular sciences 2023 Apr 28;24(9)
International journal of molecular sciences 2023 Apr 28;24(9)
Upregulation of TMEM40 is associated with the malignant behavior and promotes tumor progression in cervical cancer.
Zhang ZF, Liu F, Zhang HR, Liu B, Zheng SQ, Ye WQ, Ding JN, Zhou ZJ, Luo HX, Wu F, Guo XM, Zhou JY, Guo YH
Discover oncology 2023 Apr 13;14(1):43
Discover oncology 2023 Apr 13;14(1):43
Structural Characterization and Anti-breast Cancer Activity in vitro of a Novel Polysaccharide From Cymbopogon citratus.
Chen Y, Qiao S, Liu H, Xing H, Chen P
Frontiers in nutrition 2022;9:911838
Frontiers in nutrition 2022;9:911838
Intervention Mechanism of Hunag-Lian Jie-Du Decoction on Canonical Wnt/β-Catenin Signaling Pathway in Psoriasis Mouse Model.
Yang X, Luo G, Fu L, Huang H, Wang L, Yin L, Zhang X, Wang T, Ma X, Feng T, Ye J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3193572
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3193572
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
Li J, Yang T, Wang Q, Li Y, Wu H, Zhang M, Qi H, Zhang H, Li J
International journal of biological sciences 2022;18(9):3576-3591
International journal of biological sciences 2022;18(9):3576-3591
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.
Peng S, Chen X, Huang C, Yang C, Situ M, Zhou Q, Ling Y, Huang H, Huang M, Zhang Y, Cheng L, Zhang Q, Guo Z, Lai Y, Huang J
International journal of biological sciences 2022;18(8):3528-3543
International journal of biological sciences 2022;18(8):3528-3543
CCDC65, a Gene Knockout that leads to Early Death of Mice, acts as a potentially Novel Tumor Suppressor in Lung Adenocarcinoma.
Zhang Z, Xu P, Hu Z, Fu Z, Deng T, Deng X, Peng L, Xie Y, Long L, Zheng D, Shen P, Zhang M, Gong B, Zhu Z, Lin J, Chen R, Liu Z, Yang H, Li R, Fang W
International journal of biological sciences 2022;18(10):4171-4186
International journal of biological sciences 2022;18(10):4171-4186
CAMTA1 gene affects the ischemia-reperfusion injury by regulating CCND1.
Liu Y, Shang G, Zhang X, Liu F, Zhang C, Li Z, Jia J, Xu Y, Zhang Z, Yang S, Zhou B, Luan Y, Huang Y, Peng Y, Han T, He Y, Zheng H
Frontiers in cellular neuroscience 2022;16:868291
Frontiers in cellular neuroscience 2022;16:868291
Chrysin Ameliorates Influenza Virus Infection in the Upper Airways by Repressing Virus-Induced Cell Cycle Arrest and Mitochondria-Dependent Apoptosis.
Liu Y, Song X, Li C, Hu H, Li W, Wang L, Hu J, Liao C, Liang H, He Z, Ye L
Frontiers in immunology 2022;13:872958
Frontiers in immunology 2022;13:872958
METTL3/m(6)A/IFIT2 regulates proliferation, invasion and immunity in esophageal squamous cell carcinoma.
Ge F, Li Z, Hu J, Pu Y, Zhao F, Kong L
Frontiers in pharmacology 2022;13:1002565
Frontiers in pharmacology 2022;13:1002565
Targeting type Iγ phosphatidylinositol phosphate kinase overcomes oxaliplatin resistance in colorectal cancer.
Yu M, Wang H, Zhao W, Ge X, Huang W, Lin F, Tang W, Li A, Liu S, Li RK, Jiang SH, Xue J
Theranostics 2022;12(9):4386-4398
Theranostics 2022;12(9):4386-4398
E2F1-mediated GINS2 transcriptional activation promotes tumor progression through PI3K/AKT/mTOR pathway in hepatocellular carcinoma.
Zhang Y, Hao X, Han G, Lu Y, Chen Z, Zhang L, Wu J, Wang X
American journal of cancer research 2022;12(4):1707-1726
American journal of cancer research 2022;12(4):1707-1726
INPP4B inhibits glioma cell proliferation and immune escape via inhibition of the PI3K/AKT signaling pathway.
Sun X, Chen Y, Tao X, Zhang W, Wang X, Wang X, Ruan Z, Chen Z
Frontiers in oncology 2022;12:983537
Frontiers in oncology 2022;12:983537
Synergistic effects of nab-PTX and anti-PD-1 antibody combination against lung cancer by regulating the Pi3K/AKT pathway through the Serpinc1 gene.
Zhang J, Tang Z, Guo X, Wang Y, Zhou Y, Cai W
Frontiers in oncology 2022;12:933646
Frontiers in oncology 2022;12:933646
Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.
Yu M, Jia Y, Ma Z, Ji D, Wang C, Liang Y, Zhang Q, Yi H, Zeng L
Frontiers in oncology 2022;12:906807
Frontiers in oncology 2022;12:906807
Increased Methyl-CpG-Binding Domain Protein 2 Promotes Cigarette Smoke-Induced Pulmonary Hypertension.
Wu J, Huang Q, Li Q, Gu Y, Zhan Y, Wang T, Chen J, Zeng Z, Lv Y, Zhao J, Xia J, Xie J
Frontiers in oncology 2022;12:879793
Frontiers in oncology 2022;12:879793
HRK inhibits colorectal cancer cells proliferation by suppressing the PI3K/AKT/mTOR pathway.
Wang H, Chen Y, Yuan Q, Chen L, Dai P, Li X
Frontiers in oncology 2022;12:1053510
Frontiers in oncology 2022;12:1053510
Identification and validation of a potential key gene SGOL1 for poor prognosis in hepatocellular carcinoma based on a bioinformatics approach.
Fei X, Liu S, Liu P, Wang X, Zhu C, Hou J, Cai J, Pan Y
Frontiers in oncology 2022;12:1043161
Frontiers in oncology 2022;12:1043161
A long noncoding RNA GTF2IRD2P1 suppresses cell proliferation in bladder cancer by inhibiting the Wnt/β‑catenin signaling pathway.
Huang Z, Gao H, Qing L, Wang B, He C, Luo N, Lu C, Fan S, Gu P, Zhao H
PeerJ 2022;10:e13220
PeerJ 2022;10:e13220
SERPINA5 promotes tumour cell proliferation by modulating the PI3K/AKT/mTOR signalling pathway in gastric cancer.
Fan M, Xiong X, Han L, Zhang L, Gao S, Liu L, Wang X, Huang C, Tong D, Yang J, Zhao L, Shao Y
Journal of cellular and molecular medicine 2022 Sep;26(18):4837-4846
Journal of cellular and molecular medicine 2022 Sep;26(18):4837-4846
Combined treatment with dihydrotestosterone and lipopolysaccharide modulates prostate homeostasis by upregulating TNF-α from M1 macrophages and promotes proliferation of prostate stromal cells.
Tong Y, Guo YJ, Zhang Q, Bi HX, Kai K, Zhou RY
Asian journal of andrology 2022 Sep-Oct;24(5):513-520
Asian journal of andrology 2022 Sep-Oct;24(5):513-520
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
Gu H, Zhu S, Peng C, Wei Z, Shen Y, Yuan C, Yang H, Cui H, Yang L
International journal of molecular sciences 2022 Sep 5;23(17)
International journal of molecular sciences 2022 Sep 5;23(17)
Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.
Wang Z, Wang MM, Geng Y, Ye CY, Zang YS
Journal of translational medicine 2022 Sep 5;20(1):402
Journal of translational medicine 2022 Sep 5;20(1):402
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
Xing J, Chen W, Chen K, Zhu S, Lin F, Qi Y, Zhang Y, Han S, Rao T, Ruan Y, Zhao S, Yu W, Cheng F
Cancers 2022 Sep 30;14(19)
Cancers 2022 Sep 30;14(19)
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
Li H, Li K, Shu D, Shen M, Tan Z, Zhang W, Pu D, Tan W, Tang Z, Jin A, Liu S
Life (Basel, Switzerland) 2022 Sep 20;12(10)
Life (Basel, Switzerland) 2022 Sep 20;12(10)
Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation through the Chi-miR-214-3p/β-Catenin Axis in Cashmere Goats.
Zhang Y, Li F, Shi Y, Zhang T, Wang X
International journal of molecular sciences 2022 Sep 2;23(17)
International journal of molecular sciences 2022 Sep 2;23(17)
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Yao H, Ren D, Wang Y, Wu L, Wu Y, Wang W, Li Q, Liu L
Cell death & disease 2022 Sep 2;13(9):761
Cell death & disease 2022 Sep 2;13(9):761
Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE.
Ye C, Li H, Li Y, Zhang Y, Liu G, Mi H, Li H, Xiao Q, Niu L, Yu X
iScience 2022 Sep 16;25(9):104872
iScience 2022 Sep 16;25(9):104872
Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy.
Bian Y, Shi C, Song S, Mu L, Wu M, Qiu D, Dong J, Zhang W, Yuan C, Wang D, Zhou Z, Dong X, Shi Y
Cell and tissue research 2022 Oct;390(1):93-112
Cell and tissue research 2022 Oct;390(1):93-112
CTPS cytoophidia formation affects cell cycle progression and promotes TSN‑induced apoptosis of MKN45 cells.
Fu X, Chen W, Pan Y, Liu C, Zhang Z, Shao S, Zhang W
Molecular medicine reports 2022 Oct;26(4)
Molecular medicine reports 2022 Oct;26(4)
HCV Core protein represses DKK3 expression via epigenetic silencing and activates the Wnt/β-catenin signaling pathway during the progression of HCC.
Wang X, Zhou Y, Wang C, Zhao Y, Cheng Y, Yu S, Li X, Zhang W, Zhang Y, Quan H
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Oct;24(10):1998-2009
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Oct;24(10):1998-2009
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Liang W, Chen Q, Cheng S, Wei R, Li Y, Yao C, Ouyang Z, Kang D, Chen A, Liu Z, Li K, Bai X, Li Q, Huang B
Nature aging 2022 Oct;2(10):906-922
Nature aging 2022 Oct;2(10):906-922
Transfer RNA-derived fragment 5'tRF-Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen-related cell adhesion molecule 1.
Liu D, Wu C, Wang J, Zhang L, Sun Z, Chen S, Ding Y, Wang W
Cancer science 2022 Oct;113(10):3476-3488
Cancer science 2022 Oct;113(10):3476-3488
RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
Xu J, Shi P, Xia F, Zhao X, Chen J, Geng R, Cui H, Yang L
International journal of molecular sciences 2022 Oct 10;23(19)
International journal of molecular sciences 2022 Oct 10;23(19)
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Fang J, Ma Y, Li Y, Li J, Zhang X, Han X, Ma S, Guan F
Molecular carcinogenesis 2022 Nov;61(11):1043-1055
Molecular carcinogenesis 2022 Nov;61(11):1043-1055
Hepatocyte-derived VEGFA accelerates the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via activating hepatic stellate cells.
Shen H, Yu H, Li QY, Wei YT, Fu J, Dong H, Cao D, Guo LN, Chen L, Yang Y, Xu Y, Wu MC, Wang HY, Chen Y
Acta pharmacologica Sinica 2022 Nov;43(11):2917-2928
Acta pharmacologica Sinica 2022 Nov;43(11):2917-2928
Lysine stimulates the development of the murine mammary gland at puberty via PI3K/AKT/mTOR signalling axis.
Li W, Long X, Li F, Cao Y, Liu J, Fu S, Guo W, Hu G
Journal of animal physiology and animal nutrition 2022 Nov;106(6):1420-1430
Journal of animal physiology and animal nutrition 2022 Nov;106(6):1420-1430
Blockade of c-Met-Mediated Signaling Pathways by E7050 Suppresses Growth and Promotes Apoptosis in Multidrug-Resistant Human Uterine Sarcoma Cells.
Huang TT, Chen CM, Lan YW, Lin SS, Choo KB, Chong KY
International journal of molecular sciences 2022 Nov 28;23(23)
International journal of molecular sciences 2022 Nov 28;23(23)
Discovery of a Novel Bloom's Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer.
Ma XY, Xu HQ, Zhao JF, Ruan Y, Chen B
International journal of molecular sciences 2022 Nov 26;23(23)
International journal of molecular sciences 2022 Nov 26;23(23)
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
Peng T, Liu M, Hu L, Guo D, Wang D, Qi B, Ren G, Hu C, Zhang F, Chun HJ, Song L, Hu J, Li Y
Biology direct 2022 Nov 16;17(1):32
Biology direct 2022 Nov 16;17(1):32
Potential mechanisms underlying the promoting effects of 3D collagen scaffold culture on stemness and drug resistance of glioma cells.
Jia W, Zhu H, Zhao M, Zhou Q, Yin W, Liu W, Wang L, Xiao Z, Jiang X, Dai J, Ren C
Biochimica et biophysica acta. Molecular basis of disease 2022 Nov 1;1868(11):166522
Biochimica et biophysica acta. Molecular basis of disease 2022 Nov 1;1868(11):166522
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Huang Z, Chen H, Tan P, Huang M, Shi H, Sun B, Cheng Y, Li T, Mou Z, Li Q, Fu W
Drug development research 2022 May;83(3):721-734
Drug development research 2022 May;83(3):721-734
The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway.
Yu W, Xu G, Chen H, Xiao L, Liu G, Hu P, Li S, Kasim V, Zeng C, Tong X
Acta pharmaceutica Sinica. B 2022 May;12(5):2315-2329
Acta pharmaceutica Sinica. B 2022 May;12(5):2315-2329
In vitro and in vivo anti-lymphoma effects of Ophiorrhiza pumila extract.
Fan L, Liao W, Chen Z, Li S, Yang A, Chen MM, Liu H, Liu F
Aging 2022 May 3;14(9):3801-3812
Aging 2022 May 3;14(9):3801-3812
Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.
Zheng ZY, Chu MY, Lin W, Zheng YQ, Xu XE, Chen Y, Liao LD, Wu ZY, Wang SH, Li EM, Xu LY
Cell death & disease 2022 May 25;13(5):496
Cell death & disease 2022 May 25;13(5):496
Arylquin 1 (Potent Par-4 Secretagogue) Inhibits Tumor Progression and Induces Apoptosis in Colon Cancer Cells.
Chen YT, Tseng TT, Tsai HP, Huang MY
International journal of molecular sciences 2022 May 18;23(10)
International journal of molecular sciences 2022 May 18;23(10)
Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway.
Zhao B, Li J, Zhang X, Dai Y, Yang N, Bao Z, Chen Y, Wu X
International journal of biological macromolecules 2022 May 15;207:110-120
International journal of biological macromolecules 2022 May 15;207:110-120
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
Xu H, Cui Y, Liu X, Zheng X, Liu J, Hu X, Gao F, Hu X, Li M, Wei X, Gao Y, Zhao Y
Molecular biology reports 2022 Mar;49(3):1871-1882
Molecular biology reports 2022 Mar;49(3):1871-1882
A novel mechanism of the lncRNA PTTG3P/miR-142-5p/JAG1 axis modulating tongue cancer cell phenotypes through the Notch1 signaling.
Zhang T, Liu X, Su K, Zheng Q, Liu P, Xu Z, Zhang Y
Cells & development 2022 Mar;169:203762
Cells & development 2022 Mar;169:203762
Cyclin D1 mediated by the nuclear translocation of nuclear factor kappa B exerts an oncogenic role in lung cancer.
Wang X, Liu X, Yang Y, Yang D
Bioengineered 2022 Mar;13(3):6866-6879
Bioengineered 2022 Mar;13(3):6866-6879
Pseudophosphatase STYX is induced by Helicobacter pylori and promotes gastric cancer progression by inhibiting FBXO31 function.
Liu J, Zang Y, Ma C, Wang D, Tian Z, Xu X, Li W, Jia J, Liu Z
Cell death & disease 2022 Mar 25;13(3):268
Cell death & disease 2022 Mar 25;13(3):268
Long noncoding RNA Gm31629 protects against mucosal damage in experimental colitis via YB-1/E2F pathway.
Feng X, Xiao Y, He J, Yang M, Guo Q, Su T, Huang Y, Yi J, Li CJ, Luo XH, Liu XW, Zhou HY
JCI insight 2022 Mar 22;7(6)
JCI insight 2022 Mar 22;7(6)
HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway.
Guo K, Ma Z, Zhang Y, Han L, Shao C, Feng Y, Gao F, Di S, Zhang Z, Zhang J, Tabbò F, Ekman S, Suda K, Cappuzzo F, Han J, Li X, Yan X
Journal of experimental & clinical cancer research : CR 2022 Mar 11;41(1):91
Journal of experimental & clinical cancer research : CR 2022 Mar 11;41(1):91
Transcription Factor Specificity Protein 1 Regulates Inflammation and Fibrin Deposition in Nasal Polyps Via the Regulation of microRNA-125b and the Wnt/β-catenin Signaling Pathway.
Song L, Wang X, Qu X, Lv C
Inflammation 2022 Jun;45(3):1118-1132
Inflammation 2022 Jun;45(3):1118-1132
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
Ji R, Shi Q, Cao Y, Zhang J, Zhao C, Zhao H, Sayyed Y, Fu L, Li LY
The Journal of biological chemistry 2022 Jun;298(6):102033
The Journal of biological chemistry 2022 Jun;298(6):102033
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H(2)S in Diabetes.
Xi Y, Wen X, Zhang Y, Jiao L, Bai S, Shi S, Chang G, Wu R, Sun F, Hao J, Li H
Aging and disease 2022 Jun;13(3):910-926
Aging and disease 2022 Jun;13(3):910-926
Paired box 8 facilitates the c-MYC related cell cycle progress in TP53-mutation uterine corpus endometrial carcinoma through interaction with DDX5.
Qiu P, Jie Y, Ma C, Chen H, Qin Y, Tu K, Wang L, Zhang Z
Cell death discovery 2022 Jun 7;8(1):276
Cell death discovery 2022 Jun 7;8(1):276
Near-Infrared Light-Responsive Nanoinhibitors for Tumor Suppression through Targeting and Regulating Anion Channels.
Li C, Shi S, Gao D, Li B, Song G, Chen Y, An H, Xing C
ACS applied materials & interfaces 2022 Jul 20;14(28):31715-31726
ACS applied materials & interfaces 2022 Jul 20;14(28):31715-31726
Caffeic Acid, an Active Ingredient in Coffee, Combines with DOX for Multitarget Combination Therapy of Lung Cancer.
Bai X, Li S, Liu X, An H, Kang X, Guo S
Journal of agricultural and food chemistry 2022 Jul 13;70(27):8326-8337
Journal of agricultural and food chemistry 2022 Jul 13;70(27):8326-8337
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Li H, Sun F, Bai S, Chang G, Wu R, Wei Y, Wen X, Xi Y, Hao J, Zaid A
International journal of molecular medicine 2022 Jan;49(1)
International journal of molecular medicine 2022 Jan;49(1)
Knockdown of EphB3 inhibits cell proliferation partly through the AKT signaling pathway and represses epithelial-mesenchymal transition in esophageal squamous cell carcinoma.
Tang L, Wang L, Yu T, Xu T, Zhang L, Shu Y
Translational cancer research 2022 Jan;11(1):85-98
Translational cancer research 2022 Jan;11(1):85-98
Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies.
Wu X, Wang Y, Fan X, Xu X, Sun W
Aging 2022 Jan 7;14(1):410-429
Aging 2022 Jan 7;14(1):410-429
Betulinic acid self-assembled nanoparticles for effective treatment of glioblastoma.
Li Y, Wang Y, Gao L, Tan Y, Cai J, Ye Z, Chen AT, Xu Y, Zhao L, Tong S, Sun Q, Liu B, Zhang S, Tian D, Deng G, Zhou J, Chen Q
Journal of nanobiotechnology 2022 Jan 21;20(1):39
Journal of nanobiotechnology 2022 Jan 21;20(1):39
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
He X, Wang J, Zhou R, Yu S, Jiang J, Zhou Q
Toxicology and applied pharmacology 2022 Jan 15;435:115834
Toxicology and applied pharmacology 2022 Jan 15;435:115834
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
Jin YM, Ye Y, Bao WQ, Tong Y, Ni SB, Liu JP, Zhao B
Journal of receptor and signal transduction research 2022 Feb;42(1):1-8
Journal of receptor and signal transduction research 2022 Feb;42(1):1-8
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
Tang W, Xue J, Luo L, Wang Y, Cai X, Liu Y, Huang D, Wang X, He T, Lu D, Yang F
Molecular medicine reports 2022 Feb;25(2)
Molecular medicine reports 2022 Feb;25(2)
PRUNE2 inhibits progression of colorectal cancer in vitro and in vivo.
Li T, Huang S, Yan W, Zhang Y, Guo Q
Experimental and therapeutic medicine 2022 Feb;23(2):169
Experimental and therapeutic medicine 2022 Feb;23(2):169
The miR-34a/WNT7B modulates the sensitivity of cholangiocarcinoma cells to p53-mediated photodynamic therapy toxicity.
Han Y, Yang Y, Huang S, Yao L, Wu L
Biochemical and biophysical research communications 2022 Feb 5;591:54-61
Biochemical and biophysical research communications 2022 Feb 5;591:54-61
FERMT1 contributes to the migration and invasion of nasopharyngeal carcinoma through epithelial-mesenchymal transition and cell cycle arrest.
Li L, Li P, Zhang W, Zhou H, Guo E, Hu G, Zhang L
Cancer cell international 2022 Feb 10;22(1):70
Cancer cell international 2022 Feb 10;22(1):70
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
Qin J, Sun X, Ma Y, Cheng Y, Ma Q, Jing W, Qu S, Liu L
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Xu M, Ren L, Fan J, Huang L, Zhou L, Li X, Ye X
Life sciences 2022 Feb 1;290:120266
Life sciences 2022 Feb 1;290:120266
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Bian Y, Xue M, Guo X, Jiang W, Zhao Y, Zhang Z, Wang X, Hu Y, Zhang Q, Dun W, Zhang L
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Characterization and functional analysis of lncRNA2690 in regulating the growth cycle of the hair follicle in rabbits.
Bao Z, Zhai P, Yao F, Ren Y, Zhao B, Chen Y, Wu X
Animal genetics 2022 Dec;53(6):841-848
Animal genetics 2022 Dec;53(6):841-848
ALG8 Fuels Stemness Through Glycosylation of the WNT/Beta-Catenin Signaling Pathway in Colon Cancer.
Wu X, Wang B, Su Y, He D, Mo H, Zheng M, Meng Z, Ren L, Zhang X, Ren D, Li C
DNA and cell biology 2022 Dec;41(12):1075-1083
DNA and cell biology 2022 Dec;41(12):1075-1083
PRRX1 promotes colorectal cancer stemness and chemoresistance via the JAK2/STAT3 axis by targeting IL-6.
Zhong L, Tan W, Yang Q, Zou Z, Zhou R, Huang Y, Qiu Z, Zheng K, Huang Z
Journal of gastrointestinal oncology 2022 Dec;13(6):2989-3008
Journal of gastrointestinal oncology 2022 Dec;13(6):2989-3008
miR-29b-3p inhibits 22Rv1 prostate cancer cell proliferation through the YWHAE/BCL-2 regulatory axis.
Zhao J, Ma X, Xu H
Oncology letters 2022 Aug;24(2):289
Oncology letters 2022 Aug;24(2):289
NSUN2-mediated RNA m(5)C modification modulates uveal melanoma cell proliferation and migration.
Luo G, Xu W, Chen X, Wang S, Wang J, Dong F, Hu DN, Reinach PS, Yan D
Epigenetics 2022 Aug;17(8):922-933
Epigenetics 2022 Aug;17(8):922-933
LAP3 contributes to IFN-γ-induced arginine depletion and malignant transformation of bovine mammary epithelial cells.
Li L, Li F, Hu X, Wu Z, Ren W, Wang T, Ji Z, Li N, Gu J, Sun C, Feng X, Han W, Huang J, Lei L
BMC cancer 2022 Aug 8;22(1):864
BMC cancer 2022 Aug 8;22(1):864
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Hu P, Xu Y, Jiang Y, Huang J, Liu Y, Wang D, Tao T, Sun Z, Liu Y
European journal of pharmacology 2022 Aug 5;928:175093
European journal of pharmacology 2022 Aug 5;928:175093
S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c-Myc pathway in patients with estrogen receptor-positive breast cancer.
Mo H, Liu X, Xue Y, Chen H, Guo S, Li Z, Wang S, Li C, Han J, Fu M, Song Y, Li D, Ma F
Molecular cancer 2022 Aug 30;21(1):171
Molecular cancer 2022 Aug 30;21(1):171
DNA Methylation Mediates lncRNA2919 Regulation of Hair Follicle Regeneration.
Zhao B, Li J, Liu M, Yang N, Bao Z, Zhang X, Dai Y, Cai J, Chen Y, Wu X
International journal of molecular sciences 2022 Aug 22;23(16)
International journal of molecular sciences 2022 Aug 22;23(16)
The effects of Jiawei Duhuo Jisheng mixture on Wnt/β-catenin signaling pathway in the synovium inflamed by knee osteoarthritis: An in vitro and in vivo experiment.
Shi Q, Huang L, Duan J, Kuang G, Lu M, Tan X
Journal of ethnopharmacology 2022 Aug 10;294:115363
Journal of ethnopharmacology 2022 Aug 10;294:115363
Dematin inhibits glioblastoma malignancy through RhoA-mediated CDKs downregulation and cytoskeleton remodeling.
Wang M, Chen B, Zhang W, Zhang F, Qiu Y, Lin Y, Yang S
Experimental cell research 2022 Aug 1;417(1):113196
Experimental cell research 2022 Aug 1;417(1):113196
Elevated FAM84B promotes cell proliferation via interacting with NPM1 in esophageal squamous cell carcinoma.
Wang F, Cheng C, Wang X, Chen F, Li H, Zhou Y, Wang Y, Hu X, Kong P, Zhang L, Cheng X, Cui Y
Cell death discovery 2022 Apr 8;8(1):182
Cell death discovery 2022 Apr 8;8(1):182
Bolbostemma paniculatum (Maxim.) Franquet extract suppresses the development of colorectal cancer through downregulation of PI3K/Akt pathway.
Li Y, Sun Y, Zhang Q, Liu Y, Niu Y, Li X, Cai D
Journal of ethnopharmacology 2022 Apr 6;287:114937
Journal of ethnopharmacology 2022 Apr 6;287:114937
CYLD deficiency enhances metabolic reprogramming and tumor progression in nasopharyngeal carcinoma via PFKFB3.
Wang L, Lin Y, Zhou X, Chen Y, Li X, Luo W, Zhou Y, Cai L
Cancer letters 2022 Apr 28;532:215586
Cancer letters 2022 Apr 28;532:215586
β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway.
Nie Q, Peng WW, Wang Y, Zhong L, Zhang X, Zeng L
Gene 2022 Apr 15;818:146207
Gene 2022 Apr 15;818:146207
CDK5RAP3 acts as a putative tumor inhibitor in papillary thyroid carcinoma via modulation of Akt/GSK-3β/Wnt/β-catenin signaling.
Feng X, Jiang J, Sun L, Zhou Q
Toxicology and applied pharmacology 2022 Apr 1;440:115940
Toxicology and applied pharmacology 2022 Apr 1;440:115940
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Jin C, Ou Q, Chen J, Wang T, Zhang J, Wang Z, Wang Y, Tian H, Xu JY, Gao F, Wang J, Li J, Lu L, Xu GT
Stem cell research & therapy 2022 Apr 1;13(1):136
Stem cell research & therapy 2022 Apr 1;13(1):136
Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.
Lei X, Chen G, Li J, Wen W, Gong J, Fu J
PeerJ 2021;9:e12141
PeerJ 2021;9:e12141
Effect of Photodynamic Therapy on Gemcitabine-Resistant Cholangiocarcinoma in vitro and in vivo Through KLF10 and EGFR.
Yang Y, Li J, Yao L, Wu L
Frontiers in cell and developmental biology 2021;9:710721
Frontiers in cell and developmental biology 2021;9:710721
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
Dang NN, Li XB, Zhang M, Han C, Fan XY, Huang SH
Frontiers in cell and developmental biology 2021;9:662763
Frontiers in cell and developmental biology 2021;9:662763
NAP1L1 Functions as a Tumor Promoter via Recruiting Hepatoma-Derived Growth Factor/c-Jun Signal in Hepatocellular Carcinoma.
Zhang YW, Chen Q, Li B, Li HY, Zhao XK, Xiao YY, Liu S, Zuo S
Frontiers in cell and developmental biology 2021;9:659680
Frontiers in cell and developmental biology 2021;9:659680
CORO6 Promotes Cell Growth and Invasion of Clear Cell Renal Cell Carcinoma via Activation of WNT Signaling.
Wang X, Xiao Y, Li S, Yan Z, Luo G
Frontiers in cell and developmental biology 2021;9:647301
Frontiers in cell and developmental biology 2021;9:647301
LHPP-Mediated Histidine Dephosphorylation Suppresses the Self-Renewal of Mouse Embryonic Stem Cells.
Xia RM, Yao DB, Cai XM, Xu XQ
Frontiers in cell and developmental biology 2021;9:638815
Frontiers in cell and developmental biology 2021;9:638815
17β-Estradiol Inhibits Proliferation and Oxidative Stress in Vascular Smooth Muscle Cells by Upregulating BHLHE40 Expression.
Feng DD, Zheng B, Yu J, Zhang ML, Ma Y, Hao X, Wen JK, Zhang XH
Frontiers in cardiovascular medicine 2021;8:768662
Frontiers in cardiovascular medicine 2021;8:768662
Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.
Liu C, Chi K, Geng X, Hong Q, Mao Z, Huang Q, Liu D, Wang Y, Zhang Y, Zhou F, Cai G, Chen X, Sun X
Frontiers in medicine 2021;8:655787
Frontiers in medicine 2021;8:655787
Transcription Factors BARX1 and DLX4 Contribute to Progression of Clear Cell Renal Cell Carcinoma via Promoting Proliferation and Epithelial-Mesenchymal Transition.
Sun G, Ge Y, Zhang Y, Yan L, Wu X, Ouyang W, Wang Z, Ding B, Zhang Y, Long G, Liu M, Shi R, Zhou H, Chen Z, Ye Z
Frontiers in molecular biosciences 2021;8:626328
Frontiers in molecular biosciences 2021;8:626328
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, Qian W, Wang D, Yu D, Zhong C
Nutrition and cancer 2021;73(7):1157-1167
Nutrition and cancer 2021;73(7):1157-1167
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Zhang D, Li C, Zhang L, Li B, Wang Y, Wang R, Chen Z, Xu L, Liu T
Nutrition and cancer 2021;73(11-12):2491-2501
Nutrition and cancer 2021;73(11-12):2491-2501
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma.
Zhu L, Zheng Y, Hu R, Hu C
BioMed research international 2021;2021:5486131
BioMed research international 2021;2021:5486131
Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma.
Zhang X, Xu X, Zhang Z, Xue C, Kong Z, Wu S, Yun X, Fu Y, Zhu C, Qin X
International journal of biological sciences 2021;17(3):768-780
International journal of biological sciences 2021;17(3):768-780
Increased Collagen Type V α2 (COL5A2) in Colorectal Cancer is Associated with Poor Prognosis and Tumor Progression.
Wang J, Jiang YH, Yang PY, Liu F
OncoTargets and therapy 2021;14:2991-3002
OncoTargets and therapy 2021;14:2991-3002
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
Zhang JJ, Song CG, Dai JM, Zhang XQ, Lin P, Li L, Yang XM, Chen ZN
American journal of translational research 2021;13(5):3967-3986
American journal of translational research 2021;13(5):3967-3986
A novel function for cyclin D1 as a transcriptional role in oncogenesis and tumor development by ChIP-Seq and RNA-Seq.
Xiong Y, Wang Y, Li T, Yu X, Zeng Y, Xiao G, Zhou F, Zhou Y
Journal of Cancer 2021;12(17):5181-5192
Journal of Cancer 2021;12(17):5181-5192
Lenvatinib induces anticancer activity in gallbladder cancer by targeting AKT.
Ye J, Qi L, Liang J, Zong K, Liu W, Li R, Feng R, Zhai W
Journal of Cancer 2021;12(12):3548-3557
Journal of Cancer 2021;12(12):3548-3557
Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder Cancer.
Zhang P, Yang Q
Frontiers in genetics 2021;12:682856
Frontiers in genetics 2021;12:682856
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Wang Y, Shen H, Sun Q, Zhao L, Liu H, Ye L, Xu Y, Cai J, Li Y, Gao L, Tan Y, Liu B, Chen Q
Frontiers in pharmacology 2021;12:659511
Frontiers in pharmacology 2021;12:659511
Therapeutic Potential of CUDC-907 (Fimepinostat) for Hepatocarcinoma Treatment Revealed by Tumor Spheroids-Based Drug Screening.
Liao W, Yang W, Xu J, Yan Z, Pan M, Xu X, Zhou S, Zhu Y, Lan J, Zeng M, Han X, Li S, Li Y, Liang K, Gao Y, Peng Q
Frontiers in pharmacology 2021;12:658197
Frontiers in pharmacology 2021;12:658197
Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for Treatment of Lung Adenocarcinoma.
Guo S, Bai X, Liu Y, Shi S, Wang X, Zhan Y, Kang X, Chen Y, An H
Frontiers in pharmacology 2021;12:643489
Frontiers in pharmacology 2021;12:643489
SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.
Jiang M, Kuang Z, He Y, Cao Y, Yu T, Cheng J, Liu W, Wang W
Frontiers in endocrinology 2021;12:624309
Frontiers in endocrinology 2021;12:624309
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Liu W, Zhan Z, Zhang M, Sun B, Shi Q, Luo F, Zhang M, Zhang W, Hou Y, Xiao X, Li Y, Feng H
Theranostics 2021;11(13):6278-6292
Theranostics 2021;11(13):6278-6292
Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer.
Wang D, Li Z, Yin H
Frontiers in oncology 2021;11:751903
Frontiers in oncology 2021;11:751903
tRNA-Derived Fragment tRF-Glu-TTC-027 Regulates the Progression of Gastric Carcinoma via MAPK Signaling Pathway.
Xu W, Zhou B, Wang J, Tang L, Hu Q, Wang J, Chen H, Zheng J, Yan F, Chen H
Frontiers in oncology 2021;11:733763
Frontiers in oncology 2021;11:733763
The lncRNA CASC2 Modulates Hepatocellular Carcinoma Cell Sensitivity and Resistance to TRAIL Through Apoptotic and Non-Apoptotic Signaling.
Sun J, Xu H, Lei Z, Li Z, Zhu H, Deng Z, Yu X, Jin X, Yang Z
Frontiers in oncology 2021;11:726622
Frontiers in oncology 2021;11:726622
Role of Notch pathway in effect of mono-2-ethylhexyl phthalate on the proliferation and cell cycle of SH-SY5Y cell.
Zhang B, Li X, Zhang X, Ye J, Zhao W, Zhang M, Xing J, Qi W, Ye L
Environmental toxicology 2021 Sep;36(9):1944-1952
Environmental toxicology 2021 Sep;36(9):1944-1952
TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.
Zhu G, Herlyn M, Yang X
Nature cell biology 2021 Sep;23(9):978-991
Nature cell biology 2021 Sep;23(9):978-991
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
Bai ZM, Li XF, Yang Y, Yang YF, Lv DR, Tang LL
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma.
Wang B, Yin X, Gan W, Pan F, Li S, Xiang Z, Han X, Li D
Autophagy 2021 Sep;17(9):2475-2493
Autophagy 2021 Sep;17(9):2475-2493
The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy.
Liu H, Wei J, Sang N, Zhong X, Zhou X, Yang X, Zhang J, Zuo Z, Zhou Y, Yang S, Du J, Zhao Y
Medical oncology (Northwood, London, England) 2021 Sep 7;38(10):124
Medical oncology (Northwood, London, England) 2021 Sep 7;38(10):124
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
Zeng S, Chen L, Sun Q, Zhao H, Yang H, Ren S, Liu M, Meng X, Xu H
European journal of pharmacology 2021 Sep 5;906:174253
European journal of pharmacology 2021 Sep 5;906:174253
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.
Zhang YL, Chen GL, Liu Y, Zhuang XC, Guo MQ
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Bromodomain-containing protein 9 promotes hepatocellular carcinoma progression via activating the Wnt/β-catenin signaling pathway.
Fang D, Wang MR, Guan JL, Han YY, Sheng JQ, Tian DA, Li PY
Experimental cell research 2021 Sep 15;406(2):112727
Experimental cell research 2021 Sep 15;406(2):112727
LncAY controls BMI1 expression and activates BMI1/Wnt/β-catenin signaling axis in hepatocellular carcinoma.
Chen MH, Fu LS, Zhang F, Yang Y, Wu XZ
Life sciences 2021 Sep 1;280:119748
Life sciences 2021 Sep 1;280:119748
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
Huang L, Zhang H, Zhao D, Hu H, Lu Z
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Zhou C, Liang Y, Zhou L, Yan Y, Liu N, Zhang R, Huang Y, Wang M, Tang Y, Ali DW, Wang Y, Michalak M, Chen XZ, Tang J
Autophagy 2021 Oct;17(10):3175-3195
Autophagy 2021 Oct;17(10):3175-3195
Silent information regulator 2 promotes clear cell renal cell carcinoma progression through deacetylation and small ubiquitin-related modifier 1 modification of glucose 6-phosphate dehydrogenase.
Ni Y, Yang Z, Agbana YL, Bai H, Wang L, Yang L, Yi Z, Cheng J, Zhang Q, Kuang Y, Zhu Y
Cancer science 2021 Oct;112(10):4075-4086
Cancer science 2021 Oct;112(10):4075-4086
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Zhang J, Zou L, Shi D, Liu J, Zhang J, Zhao R, Wang G, Zhang L, Ouyang L, Liu B
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Wang S, Xu X, Che D, Fan R, Gao M, Cao Y, Ge C, Feng Y, Li J, Xie S, Wang C, Dai F, Gao L, Wang Y
International journal of molecular sciences 2021 Oct 12;22(20)
International journal of molecular sciences 2021 Oct 12;22(20)
TMEM16A, a Homoharringtonine Receptor, as a Potential Endogenic Target for Lung Cancer Treatment.
Guo S, Bai X, Shi S, Deng Y, Kang X, An H
International journal of molecular sciences 2021 Oct 10;22(20)
International journal of molecular sciences 2021 Oct 10;22(20)
Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration.
Song AN, Yin XJ, Gao P, Tang H, Meng XF, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21959
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21959
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer.
Tay DJT, Song Y, Peng B, Toh TB, Hooi L, Toh DK, Hong H, Tang SJ, Han J, Gan WL, Chan THM, Krishna MS, Patil KM, Maraswami M, Loh TP, Dan YY, Zhou L, Bonney GK, Chow PK, Chen G, Chow EK, Le MTN, Chen L
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Nov 3;29(11):3258-3273
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Nov 3;29(11):3258-3273
Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness.
Xie X, Chen J, Wo D, Ma E, Ning Y, Peng J, Zhu W, Ren DN
Journal of ethnopharmacology 2021 Nov 15;280:114449
Journal of ethnopharmacology 2021 Nov 15;280:114449
Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/β-catenin pathway in hepatocellular carcinoma.
Liu X, Shan W, Li T, Gao X, Kong F, You H, Kong D, Qiao S, Tang R
BMC cancer 2021 Nov 14;21(1):1224
BMC cancer 2021 Nov 14;21(1):1224
NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth.
Liu S, Zhang Y, Cui S, Song D, Li B, Chen Q, Yao G, Gong B
Cancer cell international 2021 Nov 13;21(1):605
Cancer cell international 2021 Nov 13;21(1):605
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Li C, Li L, Ali I, Kuang M, Wang X, Wang G
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways.
Kong L, Yu Y, Guan H, Jiang L, Sun F, Li X, Huang W, Li B
International journal of molecular medicine 2021 May;47(5)
International journal of molecular medicine 2021 May;47(5)
Niacin stimulates EPH4EV mammary epithelial cell proliferation and mammary gland development in pubertal mice through activation of AKT/mTOR and ERK1/2 signaling pathways.
Cao Y, Zhang Y, Ma L, Wang J, Guo W, Cheng J, Hu G, Fu S, Liu J
Cell and tissue research 2021 May;384(2):313-324
Cell and tissue research 2021 May;384(2):313-324
Expression of COX-2 and Nrf2/GPx3 in the anterior vaginal wall tissues of women with pelvic organ prolapse.
Lin T, Ji Y, Zhao Y, Xia Z
Archives of gynecology and obstetrics 2021 May;303(5):1245-1253
Archives of gynecology and obstetrics 2021 May;303(5):1245-1253
Pyrvinium pamoate can overcome artemisinin's resistance in anaplastic thyroid cancer.
Li Y
BMC complementary medicine and therapies 2021 May 28;21(1):156
BMC complementary medicine and therapies 2021 May 28;21(1):156
Activity Components from Gynostemma pentaphyllum for Preventing Hepatic Fibrosis and of Its Molecular Targets by Network Pharmacology Approach.
Zhang Y, Shi G, Luo Z, Wang J, Wu S, Zhang X, Zhao Y
Molecules (Basel, Switzerland) 2021 May 18;26(10)
Molecules (Basel, Switzerland) 2021 May 18;26(10)
CUX1 Enhances Pancreatic Cancer Formation by Synergizing with KRAS and Inducing MEK/ERK-Dependent Proliferation.
Griesmann H, Mühl S, Riedel J, Theuerkorn K, Sipos B, Esposito I, Vanden Heuvel GB, Michl P
Cancers 2021 May 18;13(10)
Cancers 2021 May 18;13(10)
Long intergenic non-coding RNA 00473 promotes proliferation and migration of gastric cancer via the miR-16-5p/CCND2 axis and by regulating AQP3.
Zhuo S, Sun M, Bai R, Lu D, Di S, Ma T, Zou Z, Li H, Zhang Z
Cell death & disease 2021 May 15;12(5):496
Cell death & disease 2021 May 15;12(5):496
Nucleolar and spindle‑associated protein 1 promotes non‑small cell lung cancer progression and serves as an effector of myocyte enhancer factor 2D.
Ling B, Wei P, Xiao J, Cen B, Wei H, Feng X, Ye G, Li S, Zhang Z, Liang W, Huang S, Huang W
Oncology reports 2021 Mar;45(3):1044-1058
Oncology reports 2021 Mar;45(3):1044-1058
Down-regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p.
Wu J, Li Y, Liu J, Xu Y
The journal of gene medicine 2021 Mar;23(3):e3293
The journal of gene medicine 2021 Mar;23(3):e3293
LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis.
Zhu C, He X, Chen K, Huang Z, Yao A, Tian X, You Y, Zeng M
Cell cycle (Georgetown, Tex.) 2021 Mar-Mar;20(5-6):575-590
Cell cycle (Georgetown, Tex.) 2021 Mar-Mar;20(5-6):575-590
miRNA in food simultaneously controls animal viral disease and human tumorigenesis.
Cui Y, Wan H, Zhang X
Molecular therapy. Nucleic acids 2021 Mar 5;23:995-1006
Molecular therapy. Nucleic acids 2021 Mar 5;23:995-1006
The influence of phenolic environmental estrogen on the transcriptome of uterine leiomyoma cells: A whole transcriptome profiling-based analysis.
Li Z, Yin H, Shen Y, Ren M, Xu X
Ecotoxicology and environmental safety 2021 Mar 15;211:111945
Ecotoxicology and environmental safety 2021 Mar 15;211:111945
FoxP3-miR-150-5p/3p suppresses ovarian tumorigenesis via an IGF1R/IRS1 pathway feedback loop.
Zhang Q, Zhou X, Wan M, Zeng X, Luo J, Xu Y, Ji L, Zhang JA, Fan P, Zhong J, Wu J
Cell death & disease 2021 Mar 15;12(3):275
Cell death & disease 2021 Mar 15;12(3):275
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Wang F, Younis M, Luo Y, Zhang L, Yuan L
International immunopharmacology 2021 Jun;95:107532
International immunopharmacology 2021 Jun;95:107532
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Jia R, Yang F, Yan P, Ma L, Yang L, Li L
Free radical biology & medicine 2021 Jun;169:158-168
Free radical biology & medicine 2021 Jun;169:158-168
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Luo X, Cao M, Gao F, He X
Experimental hematology & oncology 2021 Jun 4;10(1):35
Experimental hematology & oncology 2021 Jun 4;10(1):35
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Jiao X, Wang B, Feng C, Song S, Tian B, Zhou C, Gao X, Sun W, Liu P
BMC cancer 2021 Jun 30;21(1):760
BMC cancer 2021 Jun 30;21(1):760
MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway.
Wang Y, Zheng Y, Chen Q, Dai Y, Li T
Archives of biochemistry and biophysics 2021 Jun 15;704:108719
Archives of biochemistry and biophysics 2021 Jun 15;704:108719
CENPE contributes to pulmonary vascular remodeling in pulmonary hypertension.
Fang X, Xie M, Liu X, He Y
Biochemical and biophysical research communications 2021 Jun 11;557:40-47
Biochemical and biophysical research communications 2021 Jun 11;557:40-47
Effect of fenofibrate on proliferation of SMMC-7721 cells via regulating cell cycle.
Li B, Jiang HY, Wang ZH, Ma YC, Bao YN, Jin Y
Human & experimental toxicology 2021 Jul;40(7):1208-1221
Human & experimental toxicology 2021 Jul;40(7):1208-1221
METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
Wang XK, Zhang YW, Wang CM, Li B, Zhang TZ, Zhou WJ, Cheng LJ, Huo MY, Zhang CH, He YL
Journal of cellular and molecular medicine 2021 Jul;25(14):6602-6617
Journal of cellular and molecular medicine 2021 Jul;25(14):6602-6617
BACH1 is transcriptionally inhibited by TET1 in hepatocellular carcinoma in a microRNA-34a-dependent manner to regulate autophagy and inflammation.
Sun X, Zhu H, Cao R, Zhang J, Wang X
Pharmacological research 2021 Jul;169:105611
Pharmacological research 2021 Jul;169:105611
miRNA-194 predicts favorable prognosis in gastric cancer and inhibits gastric cancer cell growth by targeting CCND1.
Wang J, Zhang M, Hu X, She J, Sun R, Qin S, Li D
FEBS open bio 2021 Jul;11(7):1814-1826
FEBS open bio 2021 Jul;11(7):1814-1826
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
Luo P, He WX, Li C, Chang MJ
Neuroreport 2021 Jul 7;32(10):875-881
Neuroreport 2021 Jul 7;32(10):875-881
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Li H, Dang C, Tai X, Xue L, Meng Y, Ma S, Zhang J
Scientific reports 2021 Jul 22;11(1):14985
Scientific reports 2021 Jul 22;11(1):14985
Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis.
Yang B, Li L, Tong G, Zeng Z, Tan J, Su Z, Liu Z, Lin J, Gao W, Chen J, Zeng S, Wu G, Li L, Zhu S, Liu Q, Lin L
Journal of experimental & clinical cancer research : CR 2021 Jul 16;40(1):235
Journal of experimental & clinical cancer research : CR 2021 Jul 16;40(1):235
Circular RNA-DPP4 serves an oncogenic role in prostate cancer progression through regulating miR-195/cyclin D1 axis.
Yang D, Yang B, Zhu Y, Xia Q, Zhang Y, Zhu X, Guo J, Ding T, Zheng J
Cancer cell international 2021 Jul 16;21(1):379
Cancer cell international 2021 Jul 16;21(1):379
Long noncoding RNA GAS5 accelerates diabetic wound healing and promotes lymphangiogenesis via miR-217/Prox1 axis.
He ZY, Huang MT, Cui X, Zhou ST, Wu Y, Zhang PH, Zhou J
Molecular and cellular endocrinology 2021 Jul 15;532:111283
Molecular and cellular endocrinology 2021 Jul 15;532:111283
Maternally expressed 3 protects the intestinal barrier from cardiac arrest-induced ischemia/reperfusion injury via miR-34a-3p/sirtuin 1/nuclear factor kappa B signaling.
Huang X, Pan M, Du P, Chen Y, Zhang C, Lu W, Lin J
Annals of translational medicine 2021 Jan;9(2):122
Annals of translational medicine 2021 Jan;9(2):122
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
Jiang F, Ren S, Chen Y, Zhang A, Zhu Y, Zhang Z, Li Z, Piao D
Oncology reports 2021 Jan;45(1):139-150
Oncology reports 2021 Jan;45(1):139-150
Absence of the MFG-E8 gene prevents hypoxia-induced pulmonary hypertension in mice.
Wang J, Wu J, Zhu X, Chen J, Zhao J, Xu Y, Xie J
Journal of cellular physiology 2021 Jan;236(1):587-600
Journal of cellular physiology 2021 Jan;236(1):587-600
The circular RNA circZFR phosphorylates Rb promoting cervical cancer progression by regulating the SSBP1/CDK2/cyclin E1 complex.
Zhou M, Yang Z, Wang D, Chen P, Zhang Y
Journal of experimental & clinical cancer research : CR 2021 Jan 30;40(1):48
Journal of experimental & clinical cancer research : CR 2021 Jan 30;40(1):48
Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma.
Ma J, Chen X, Lin M, Wang Z, Wu Y, Li J
Cancer cell international 2021 Jan 21;21(1):65
Cancer cell international 2021 Jan 21;21(1):65
Knockdown of CENPF inhibits the progression of lung adenocarcinoma mediated by ERβ2/5 pathway.
Hexiao T, Yuquan B, Lecai X, Yanhong W, Li S, Weidong H, Ming X, Xuefeng Z, Gaofeng P, Li Z, Minglin Z, Zheng T, Zetian Y, Xiao Z, Yi C, Lanuti M, Jinping Z
Aging 2021 Jan 10;13(2):2604-2625
Aging 2021 Jan 10;13(2):2604-2625
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Liu S, Gong Y, Xu XD, Shen H, Gao S, Bao HD, Guo SB, Yu XF, Gong J
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
Sericin inhibits MDA‑MB‑468 cell proliferation via the PI3K/Akt pathway in triple‑negative breast cancer.
Niu L, Yang S, Zhao X, Liu X, Si L, Wei M, Liu L, Cheng L, Qiao Y, Chen Z
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Wang J, Hu X, Hu X, Gao F, Li M, Cui Y, Wei X, Qin Y, Zhang C, Zhao Y, Gao Y
The international journal of biochemistry & cell biology 2021 Feb;131:105873
The international journal of biochemistry & cell biology 2021 Feb;131:105873
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Fan H, Xin T, Dong X, Yang F, Zhang R, Feng S, He D, Guo H, Pang Q
Experimental and molecular pathology 2021 Feb;118:104571
Experimental and molecular pathology 2021 Feb;118:104571
Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
Qin J, Qu S, Zhu K, Cheng Y, Pan G, Jing W, Liu X, Sun X, Liu L
Bioorganic & medicinal chemistry 2021 Feb 15;32:116003
Bioorganic & medicinal chemistry 2021 Feb 15;32:116003
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Liu S, Chen L, Chen H, Xu K, Peng X, Zhang M
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
Feng S, Liu H, Du P, Dong X, Pang Q, Guo H
Annals of translational medicine 2021 Dec;9(23):1729
Annals of translational medicine 2021 Dec;9(23):1729
Synergistic inhibitory effect of Smo inhibitor jervine and its combination with decitabine can target Hedgehog signaling pathway to inhibit myelodysplastic syndrome cell line.
Zhao F, Wang J, Yao L, Qin YT, Tuerxun N, Wang H, Jiang M, Hao JP
Hematology (Amsterdam, Netherlands) 2021 Dec;26(1):518-528
Hematology (Amsterdam, Netherlands) 2021 Dec;26(1):518-528
Cell division cycle associated 8: A novel diagnostic and prognostic biomarker for hepatocellular carcinoma.
Cui XH, Peng QJ, Li RZ, Lyu XJ, Zhu CF, Qin XH
Journal of cellular and molecular medicine 2021 Dec;25(24):11097-11112
Journal of cellular and molecular medicine 2021 Dec;25(24):11097-11112
The protective mechanism of Klotho gene-modified bone marrow mesenchymal stem cells on acute kidney injury induced by rhabdomyolysis.
Ni W, Zhang Y, Yin Z
Regenerative therapy 2021 Dec;18:255-267
Regenerative therapy 2021 Dec;18:255-267
S100A11 regulates nasal epithelial cell remodeling and inflammation in CRSwNPs via the RAGE-mediated AMPK-STAT3 pathway.
Liu C, Du H, Wang Y, Gong N, Qi W, Zhou X, Shi L
Molecular immunology 2021 Dec;140:35-46
Molecular immunology 2021 Dec;140:35-46
Senescence marker protein 30 inhibits tumor growth by reducing HDAC4 expression in non-small cell lung cancer.
Shao C, Guo K, Xu L, Zhang Y, Duan H, Feng Y, Pan M, Lu D, Ren X, Ganti AK, Hakozaki T, Han J, Yan X, Ma Z
Translational lung cancer research 2021 Dec;10(12):4558-4573
Translational lung cancer research 2021 Dec;10(12):4558-4573
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
Chen C, Wang YS, Zhang ET, Li GA, Liu WY, Li Y, Jin YH
International journal of molecular sciences 2021 Dec 6;22(23)
International journal of molecular sciences 2021 Dec 6;22(23)
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
Gong X, Tian M, Cao N, Yang P, Xu Z, Zheng S, Liao Q, Chen C, Zeng C, Jose PA, Wang DZ, Jian Z, Xiao Y, Jiang DS, Wei X, Zhang B, Wang Y, Chen K, Wu G, Zeng C
The Journal of clinical investigation 2021 Dec 15;131(24)
The Journal of clinical investigation 2021 Dec 15;131(24)
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
Cheng Y, Hu Y, Wang H, Zhao Z, Jiang X, Zhang Y, Zhang J, Tong Y, Qiu X
Journal of cellular and molecular medicine 2021 Aug;25(16):7796-7808
Journal of cellular and molecular medicine 2021 Aug;25(16):7796-7808
Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell.
Chang L, Zhou R, He Y, Meng M, Hu J, Liu Y, Pan Y, Tang Z, Yue Z
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
SETD4 in the Proliferation, Migration, Angiogenesis, Myogenic Differentiation and Genomic Methylation of Bone Marrow Mesenchymal Stem Cells.
Liao X, Wu C, Shao Z, Zhang S, Zou Y, Wang K, Ha Y, Xing J, Zheng A, Shen Z, Zheng S, Guo J, Jie W
Stem cell reviews and reports 2021 Aug;17(4):1374-1389
Stem cell reviews and reports 2021 Aug;17(4):1374-1389
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
Zhang X, Shi X, Wang J, Xu Z, He J
Aging 2021 Aug 30;13(16):20748-20761
Aging 2021 Aug 30;13(16):20748-20761
LncRNA LINC00680 promotes lung adenocarcinoma growth via binding to GATA6 and canceling GATA6-mediated suppression of SOX12 expression.
Sun X, Wang R, Tan M, Tian X, Meng J
Experimental cell research 2021 Aug 1;405(1):112653
Experimental cell research 2021 Aug 1;405(1):112653
Hybrid-cell membrane-coated nanocomplex-loaded chikusetsusaponin IVa methyl ester for a combinational therapy against breast cancer assisted by Ce6.
Xie Q, Liu Y, Long Y, Wang Z, Jiang S, Ahmed R, Daniyal M, Li B, Liu B, Wang W
Biomaterials science 2021 Apr 21;9(8):2991-3004
Biomaterials science 2021 Apr 21;9(8):2991-3004
SIRT4 is the molecular switch mediating cellular proliferation in colorectal cancer through GLS mediated activation of AKT/GSK3β/CyclinD1 pathway.
Cui Y, Bai Y, Yang J, Yao Y, Zhang C, Liu C, Shi J, Li Q, Zhang J, Lu X, Zhang Y
Carcinogenesis 2021 Apr 17;42(3):481-492
Carcinogenesis 2021 Apr 17;42(3):481-492
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
Sheng J, He X, Yu W, Chen Y, Long Y, Wang K, Zhu S, Liu Q
Cancer letters 2021 Apr 10;503:54-68
Cancer letters 2021 Apr 10;503:54-68
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
Yuan C, Yang D, Ma J, Yang J, Xue J, Song F, Liu X
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
THAP11 Functions as a Tumor Suppressor in Gastric Cancer through Regulating c-Myc Signaling Pathways.
Zhang J, Zhang H, Shi H, Wang F, Du J, Wang Y, Wei Y, Xue W, Li D, Feng Y, Yan J, Gao Y, Li J, Han J
BioMed research international 2020;2020:7838924
BioMed research international 2020;2020:7838924
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
Mao Y, Li W, Hua B, Gu X, Pan W, Chen Q, Xu B, Wang Z, Lu C
BioMed research international 2020;2020:2406159
BioMed research international 2020;2020:2406159
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
Zhang R, Liu J, Zhang W, Hua L, Qian LT, Zhou SB
Cancer cell international 2020;20:20
Cancer cell international 2020;20:20
Cancer Cell enters reversible quiescence through Intracellular Acidification to resist Paclitaxel Cytotoxicity.
Jia M, Zheng D, Wang X, Zhang Y, Chen S, Cai X, Mo L, Hu Z, Li H, Zhou Z, Li J
International journal of medical sciences 2020;17(11):1652-1664
International journal of medical sciences 2020;17(11):1652-1664
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
Song D, Xu B, Shi D, Li S, Cai Y
Open medicine (Warsaw, Poland) 2020;15(1):317-326
Open medicine (Warsaw, Poland) 2020;15(1):317-326
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Zhang X, Luo Y, Li Q
OncoTargets and therapy 2020;13:5819-5830
OncoTargets and therapy 2020;13:5819-5830
Derlin-1 Promotes the Progression of Human Hepatocellular Carcinoma via the Activation of AKT Pathway.
Fan J, Tian L, Huang S, Zhang J, Zhao B
OncoTargets and therapy 2020;13:5407-5417
OncoTargets and therapy 2020;13:5407-5417
Up-Regulated CCDC34 Contributes to the Proliferation and Metastasis of Hepatocellular Carcinoma.
Lin Z, Qu S, Peng W, Yang P, Zhang R, Zhang P, Guo D, Du J, Wu W, Tao K, Wang J
OncoTargets and therapy 2020;13:51-60
OncoTargets and therapy 2020;13:51-60
ΔNp63α promotes the expression and nuclear translocation of PTEN, leading to cisplatin resistance in oral cancer cells.
Hao T, Gan YH
American journal of translational research 2020;12(10):6187-6203
American journal of translational research 2020;12(10):6187-6203
Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.
Jing X, Chen Y, Chen Y, Shi G, Lv S, Cheng N, Feng C, Xin Z, Zhang L, Wu J
Cancer management and research 2020;12:2185-2194
Cancer management and research 2020;12:2185-2194
AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.
Xu F, Xu Y, Xiong JH, Zhang JH, Wu J, Luo J, Xiong JP
Cancer management and research 2020;12:1789-1798
Cancer management and research 2020;12:1789-1798
Activated STAT3 Could Reduce Survival in Patients with Esophageal Squamous Cell Carcinoma by Up-regulating VEGF and Cyclin D1 Expression.
Zhang N, Zhang M, Wang Z, Gao W, Sun ZG
Journal of Cancer 2020;11(7):1859-1868
Journal of Cancer 2020;11(7):1859-1868
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ren Y, Wang Y, Hao S, Yang Y, Xiong W, Qiu L, Tao J, Tang A
Journal of Cancer 2020;11(23):6939-6949
Journal of Cancer 2020;11(23):6939-6949
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1.
Yang M, Hu C, Cao Y, Liang W, Yang X, Xiao T
Frontiers in pharmacology 2020;11:622212
Frontiers in pharmacology 2020;11:622212
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
Gao L, Liu J, Xu P, Deng G, Liu B, Yuan F, Tan Y, Sun Q, Xu Y, Zhang H, Qi Y, Han S, Yang K, Geng R, Jiang H, Chen Q
Frontiers in pharmacology 2020;11:1102
Frontiers in pharmacology 2020;11:1102
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Meng F, Liu X, Lin C, Xu L, Liu J, Zhang P, Zhang X, Song J, Yan Y, Ren Z, Zhang Y
American journal of cancer research 2020;10(3):997-1011
American journal of cancer research 2020;10(3):997-1011
GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.
Cheng L, Gou L, Wei T, Zhang J
International journal of oncology 2020 Sep;57(3):858-870
International journal of oncology 2020 Sep;57(3):858-870
Aristolochic acid induces renal fibrosis by arresting proximal tubular cells in G2/M phase mediated by HIF-1α.
Zhao H, Jiang N, Han Y, Yang M, Gao P, Xiong X, Xiong S, Zeng L, Xiao Y, Wei L, Li L, Li C, Yang J, Tang C, Xiao L, Liu F, Liu Y, Sun L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12599-12614
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12599-12614
PAK6 promotes cervical cancer progression through activation of the Wnt/β-catenin signaling pathway.
Yang Q, Zhao Y, Chen Y, Chang Y, Huang A, Xu T, Li G, Wu G
Oncology letters 2020 Sep;20(3):2387-2395
Oncology letters 2020 Sep;20(3):2387-2395
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
Liu J, Shangguan Y, Sun J, Cong W, Xie Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
UBAC2 promotes bladder cancer proliferation through BCRC-3/miRNA-182-5p/p27 axis.
Gu C, Zhao K, Zhou N, Liu F, Xie F, Yu S, Feng Y, Chen L, Yang J, Tian F, Jiang G
Cell death & disease 2020 Sep 10;11(9):733
Cell death & disease 2020 Sep 10;11(9):733
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
Yu G, Liu P, Shi Y, Li S, Liu Y, Fan Z, Zhu W
Journal of neurosurgery 2020 Sep 1;133(3):918-926
Journal of neurosurgery 2020 Sep 1;133(3):918-926
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
Wang L, Xu X, Liu T, Wang J, Shen J, Guo M, Wu Y, Zhai X, Zuo D
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
Matic S, D'Souza DH, Wu T, Pangloli P, Dia VP
Immunological investigations 2020 Oct;49(7):711-725
Immunological investigations 2020 Oct;49(7):711-725
miR‑483‑3p promotes the osteogenesis of human osteoblasts by targeting Dikkopf 2 (DKK2) and the Wnt signaling pathway.
Zhou B, Peng K, Wang G, Chen W, Liu P, Chen F, Kang Y
International journal of molecular medicine 2020 Oct;46(4):1571-1581
International journal of molecular medicine 2020 Oct;46(4):1571-1581
Oncogenic gene RGC-32 is a direct target of miR-26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling.
Yang ZH, Li J, Chen WZ, Kong FS
Cell biochemistry and function 2020 Oct;38(7):943-954
Cell biochemistry and function 2020 Oct;38(7):943-954
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Feng AL, Han X, Meng X, Chen Z, Li Q, Shu W, Dai H, Zhu J, Yang Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells.
Wu Z, Zhan Y, Wang L, Tong J, Zhang L, Lin M, Jin X, Jiang L, Lou Y, Qiu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110556
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110556
PRMT5/Wnt4 axis promotes lymph-node metastasis and proliferation of laryngeal carcinoma.
Wang N, Yan H, Wu D, Zhao Z, Chen X, Long Q, Zhang C, Wang X, Deng W, Liu X
Cell death & disease 2020 Oct 15;11(10):864
Cell death & disease 2020 Oct 15;11(10):864
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26.
Jin C, Li Y, Su Y, Guo Z, Wang X, Wang S, Zhang F, Zhang Z, Shao J, Zheng S
Cell death & disease 2020 Oct 11;11(10):844
Cell death & disease 2020 Oct 11;11(10):844
Mitochondrial UQCC3 Modulates Hypoxia Adaptation by Orchestrating OXPHOS and Glycolysis in Hepatocellular Carcinoma.
Yang Y, Zhang G, Guo F, Li Q, Luo H, Shu Y, Shen Y, Gan J, Xu L, Yang H
Cell reports 2020 Nov 3;33(5):108340
Cell reports 2020 Nov 3;33(5):108340
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Zhang Y, Liu X, Yu M, Xu M, Xiao Y, Ma W, Huang L, Li X, Ye X
Life sciences 2020 Nov 1;260:118413
Life sciences 2020 Nov 1;260:118413
Metformin suppresses proliferation and invasion of drug-resistant breast cancer cells by activation of the Hippo pathway.
Liu J, Li J, Chen H, Wang R, Li P, Miao Y, Liu P
Journal of cellular and molecular medicine 2020 May;24(10):5786-5796
Journal of cellular and molecular medicine 2020 May;24(10):5786-5796
Kp-10 promotes bovine mammary epithelial cell proliferation by activating GPR54 and its downstream signaling pathways.
Li Y, Cao Y, Wang J, Fu S, Cheng J, Ma L, Zhang Q, Guo W, Kan X, Liu J
Journal of cellular physiology 2020 May;235(5):4481-4493
Journal of cellular physiology 2020 May;235(5):4481-4493
MS-275 combined with cisplatin exerts synergistic antitumor effects in human esophageal squamous cell carcinoma cells.
Liu T, Guan F, Wang Y, Zhang Z, Li Y, Cui Y, Li Z, Liu H, Zhang Y, Wang Y, Ma S
Toxicology and applied pharmacology 2020 May 15;395:114971
Toxicology and applied pharmacology 2020 May 15;395:114971
MiR-193b-5p inhibits proliferation and enhances radio-sensitivity by downregulating the AKT/mTOR signaling pathway in tongue cancer.
Jiang L, He C, Zhang X, Chen Y, Li G
Translational cancer research 2020 Mar;9(3):1851-1860
Translational cancer research 2020 Mar;9(3):1851-1860
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Li K, Zhang J, Tian Y, He Y, Xu X, Pan W, Gao Y, Chen F, Wei L
Oncogene 2020 Mar;39(11):2258-2274
Oncogene 2020 Mar;39(11):2258-2274
Increased expression of hematological and neurological expressed 1 (HN1) is associated with a poor prognosis of hepatocellular carcinoma and its knockdown inhibits cell growth and migration partly by down-regulation of c-Met.
Chen JJ, Sun X, Mao QQ, Jiang XY, Zhao XG, Xu WJ, Zhong L
The Kaohsiung journal of medical sciences 2020 Mar;36(3):196-205
The Kaohsiung journal of medical sciences 2020 Mar;36(3):196-205
Ablation of Gsa impairs renal tubule proliferation after injury via CDK2/cyclin E.
Liu L, Deng Y, Cai Y, Lu P, Guo Y, Zhang C, Li Q, Zhang T, Han M, Xu G
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F793-F803
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F793-F803
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Pan H, Liu F, Wang J, Zhao M, Wang D, Jia C, Wang T, Chen Z, Fan Y, Liang D, Meng Q
Molecular carcinogenesis 2020 Jun;59(6):575-589
Molecular carcinogenesis 2020 Jun;59(6):575-589
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
Peng F, Li G, Xie Y, Yin HY, Li XJ, Yang YD
Journal of food biochemistry 2020 Jun;44(6):e13222
Journal of food biochemistry 2020 Jun;44(6):e13222
ASH2L is involved in promotion of endometrial cancer progression via upregulation of PAX2 transcription.
Zeng K, Wu Y, Wang C, Wang S, Sun H, Zou R, Sun G, Song H, Liu W, Sun N, Wei S, Liu W, Su Y, Zhou T, Zhang Y, Zhao Y
Cancer science 2020 Jun;111(6):2062-2077
Cancer science 2020 Jun;111(6):2062-2077
Radiation-Induced DNMT3B Promotes Radioresistance in Nasopharyngeal Carcinoma through Methylation of p53 and p21.
Wu C, Guo E, Ming J, Sun W, Nie X, Sun L, Peng S, Luo M, Liu D, Zhang L, Mei Q, Long G, Hu G, Hu G
Molecular therapy oncolytics 2020 Jun 26;17:306-319
Molecular therapy oncolytics 2020 Jun 26;17:306-319
HnRNP A1 - mediated alternative splicing of CCDC50 contributes to cancer progression of clear cell renal cell carcinoma via ZNF395.
Sun G, Zhou H, Chen K, Zeng J, Zhang Y, Yan L, Yao W, Hu J, Wang T, Xing J, Xiao K, Wu L, Ye Z, Xu H
Journal of experimental & clinical cancer research : CR 2020 Jun 19;39(1):116
Journal of experimental & clinical cancer research : CR 2020 Jun 19;39(1):116
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196
International journal of oncology 2020 Jul;57(1):183-196
miR‑96 exerts an oncogenic role in the progression of cervical cancer by targeting CAV‑1.
Chen Y, Liu C, Xie B, Chen S, Zhuang Y, Zhang S
Molecular medicine reports 2020 Jul;22(1):543-550
Molecular medicine reports 2020 Jul;22(1):543-550
Garcinol acts as an antineoplastic agent in human gastric cancer by inhibiting the PI3K/AKT signaling pathway.
Zheng Y, Guo C, Zhang X, Wang X, Ma A
Oncology letters 2020 Jul;20(1):667-676
Oncology letters 2020 Jul;20(1):667-676
PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells.
Chen J, Yang HM, Zhou HC, Peng RR, Niu ZX, Kang CY
Oncology letters 2020 Jul;20(1):639-646
Oncology letters 2020 Jul;20(1):639-646
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J
Molecular cancer 2020 Jul 29;19(1):118
Molecular cancer 2020 Jul 29;19(1):118
The interaction of tumor cells and myeloid-derived suppressor cells in chronic myelogenous leukemia.
Xu H, Liu J, Shen N, Zhao Z, Cui J, Zhou S, Jiang L, Zhu X, Tang L, Liang H, Liu W, Zhu Z, Meng L, Zhu X
Leukemia & lymphoma 2020 Jan;61(1):128-137
Leukemia & lymphoma 2020 Jan;61(1):128-137
Transcription factor E2F4 is a positive regulator of milk biosynthesis and proliferation of bovine mammary epithelial cells.
Zhen Z, Zhang M, Yuan X, Li M
Cell biology international 2020 Jan;44(1):229-241
Cell biology international 2020 Jan;44(1):229-241
Par6 regulates cell cycle progression through enhancement of Akt/PI3K/GSK-3β signaling pathway activation in glioma.
Liu P, Zhu C, Luo J, Lan S, Su D, Wang Q, Wei Z, Cui W, Xu C, Yang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1481-1496
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1481-1496
LINC00511 contributes to glioblastoma tumorigenesis and epithelial-mesenchymal transition via LINC00511/miR-524-5p/YB1/ZEB1 positive feedback loop.
Du X, Tu Y, Liu S, Zhao P, Bao Z, Li C, Li J, Pan M, Ji J
Journal of cellular and molecular medicine 2020 Jan;24(2):1474-1487
Journal of cellular and molecular medicine 2020 Jan;24(2):1474-1487
SOX6 suppresses the development of lung adenocarcinoma by regulating expression of p53, p21(CIPI) , cyclin D1 and β-catenin.
Lv L, Zhou M, Zhang J, Liu F, Qi L, Zhang S, Bi Y, Yu Y
FEBS open bio 2020 Jan;10(1):135-146
FEBS open bio 2020 Jan;10(1):135-146
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
Wu J, Lu K, Zhu M, Xie X, Ding Y, Shao X, Chen Y, Liu J, Xu M, Xu Y, Zhou J, Shen X, Zhu C
Biochemical and biophysical research communications 2020 Jan 22;521(4):984-990
Biochemical and biophysical research communications 2020 Jan 22;521(4):984-990
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
Liao X, Song G, Xu Z, Bu Y, Chang F, Jia F, Xiao X, Ren X, Zhang M, Jia Q
BMC cancer 2020 Jan 13;20(1):31
BMC cancer 2020 Jan 13;20(1):31
TOB1 suppresses proliferation in K-Ras wild-type pancreatic cancer.
Bai Y, Qiao L, Xie N, Li Y, Nie Y, Pan Y, Shi Y, Wang J, Liu N
Cancer medicine 2020 Feb;9(4):1503-1514
Cancer medicine 2020 Feb;9(4):1503-1514
Acetyl-11-keto-β-boswellic acid triggers premature senescence via induction of DNA damage accompanied by impairment of DNA repair genes in hepatocellular carcinoma cells in vitro and in vivo.
Wang S, Wang H, Sun B, Li D, Wu J, Li J, Tian X, Qin C, Chang H, Liu Y
Fundamental & clinical pharmacology 2020 Feb;34(1):65-76
Fundamental & clinical pharmacology 2020 Feb;34(1):65-76
Pizotifen inhibits the proliferation and invasion of gastric cancer cells.
Jiang Y, Wang W, Wu X, Shi J
Experimental and therapeutic medicine 2020 Feb;19(2):817-824
Experimental and therapeutic medicine 2020 Feb;19(2):817-824
Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.
Liu Y, Zhang M, He T, Yang W, Wang L, Zhang L, Guo M
Clinical epigenetics 2020 Feb 10;12(1):22
Clinical epigenetics 2020 Feb 10;12(1):22
Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress.
Gou W, Luo N, Wei H, Wu H, Yu X, Duan Y, Bi C, Ning H, Hou W, Li Y
Pharmaceutical biology 2020 Dec;58(1):707-715
Pharmaceutical biology 2020 Dec;58(1):707-715
Heat-Shock protein A12A is a novel PCNA-binding protein and promotes hepatocellular carcinoma growth.
Cheng H, Cao X, Min X, Zhang X, Kong Q, Mao Q, Li R, Xue B, Fang L, Liu L, Ding Z
The FEBS journal 2020 Dec;287(24):5464-5477
The FEBS journal 2020 Dec;287(24):5464-5477
Sirtuin 5 regulates the proliferation, invasion and migration of prostate cancer cells through acetyl-CoA acetyltransferase 1.
Guan J, Jiang X, Gai J, Sun X, Zhao J, Li J, Li Y, Cheng M, Du T, Fu L, Li Q
Journal of cellular and molecular medicine 2020 Dec;24(23):14039-14049
Journal of cellular and molecular medicine 2020 Dec;24(23):14039-14049
Notch3 is involved in the proliferation of renal cancer cells via regulation of cell cycle progression and HIF-2α.
Han Q, Han F, Fan Y, Lian B, Xiao J, Sun W, Han D, Kou H, Li C, Wu B
Oncology letters 2020 Dec;20(6):379
Oncology letters 2020 Dec;20(6):379
MicroRNA-1236-3p inhibits human osteosarcoma growth.
Li J, Chen J, Hu Z, Xu W
Oncology letters 2020 Dec;20(6):367
Oncology letters 2020 Dec;20(6):367
GEF-independent Ran activation shifts a fraction of the protein to the cytoplasm and promotes cell proliferation.
Zhou J, Tan Y, Zhang Y, Tong A, Shen X, Sun X, Jia D, Sun Q
Molecular biomedicine 2020 Dec 30;1(1):18
Molecular biomedicine 2020 Dec 30;1(1):18
S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression.
He W, Zhang J, Liu B, Liu X, Liu G, Xie L, He J, Wei M, Li K, Ma J, Dong R, Ma D, Dong K, Ye M
Molecular therapy oncolytics 2020 Dec 16;19:149-162
Molecular therapy oncolytics 2020 Dec 16;19:149-162
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Liu D, Zhang H, Cui M, Chen C, Feng Y
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
TMEM16A-inhibitor loaded pH-responsive nanoparticles: A novel dual-targeting antitumor therapy for lung adenocarcinoma.
Guo S, Qiu L, Chen Y, Wang X, Ma B, Qu C, Cui J, Zhang H, Xing C, Zhan Y, An H
Biochemical pharmacology 2020 Aug;178:114062
Biochemical pharmacology 2020 Aug;178:114062
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.
Deng X, Zhao J, Qu L, Duan Z, Fu R, Zhu C, Fan D
Biochemical pharmacology 2020 Aug;178:114038
Biochemical pharmacology 2020 Aug;178:114038
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Liu YC, Tsai JJ, Weng YS, Hsu FT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Long Non-coding RNA PEBP1P2 Suppresses Proliferative VSMCs Phenotypic Switching and Proliferation in Atherosclerosis.
He X, Lian Z, Yang Y, Wang Z, Fu X, Liu Y, Li M, Tian J, Yu T, Xin H
Molecular therapy. Nucleic acids 2020 Aug 19;22:84-98
Molecular therapy. Nucleic acids 2020 Aug 19;22:84-98
Prazosin inhibits the proliferation and survival of acute myeloid leukaemia cells through down-regulating TNS1.
Sun X, Yang S, Song W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109731
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109731
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Chen Z, Yuan SJ, Li K, Zhang Q, Li TF, An HC, Xu HZ, Yue Y, Han M, Xu YH, Komatsu N, Zhao L, Chen X
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
Li X, Zhang Y, Chai X, Zhou S, Zhang H, He J, Zhou R, Cai L, Chen L, Tao G
American journal of cancer research 2019;9(5):887-905
American journal of cancer research 2019;9(5):887-905
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473
Theranostics 2019;9(5):1453-1473
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L
Theranostics 2019;9(17):5065-5084
Theranostics 2019;9(17):5065-5084
Celastrol attenuates ox-LDL-induced mesangial cell proliferation via suppressing NLRP3 inflammasome activation.
Sun Z, Li Y, Qian Y, Wu M, Huang S, Zhang A, Zhang Y, Jia Z
Cell death discovery 2019;5:114
Cell death discovery 2019;5:114
GRP78 regulates milk biosynthesis and the proliferation of bovinemammaryepithelial cells through the mTOR signaling pathway.
Liu Y, Wang X, Zhen Z, Yu Y, Qiu Y, Xiang W
Cellular & molecular biology letters 2019;24:57
Cellular & molecular biology letters 2019;24:57
Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.
Li W, Cao J, Liu J, Chu W, Zhang C, Chen S, Kang Z
Cellular & molecular biology letters 2019;24:19
Cellular & molecular biology letters 2019;24:19
LncRNA FEZF1-AS1 Promotes TGF-β2-Mediated Proliferation and Migration in Human Lens Epithelial Cells SRA01/04.
Wang Y, Chen L, Gu Y, Wang Y, Yuan Y, Zhu Q, Bi M, Gu S
Journal of ophthalmology 2019;2019:4736203
Journal of ophthalmology 2019;2019:4736203
Strand-specific miR-28-3p and miR-28-5p have differential effects on nasopharyngeal cancer cells proliferation, apoptosis, migration and invasion.
Lv Y, Yang H, Ma X, Wu G
Cancer cell international 2019;19:187
Cancer cell international 2019;19:187
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, Hu X, Liang H, Wen N, Zhang S, Guo B, Zhang L
International journal of medical sciences 2019;16(12):1573-1582
International journal of medical sciences 2019;16(12):1573-1582
Adiponectin Suppresses Human Pancreatic Cancer Growth through Attenuating the β-Catenin Signaling Pathway.
Jiang J, Fan Y, Zhang W, Shen Y, Liu T, Yao M, Gu J, Tu H, Gan Y
International journal of biological sciences 2019;15(2):253-264
International journal of biological sciences 2019;15(2):253-264
Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
Zhao Y, Zhang Y, Vazirinejad Mehdiabad M, Zhou K, Chen Y, Li L, Guo J, Xu C
PloS one 2019;14(10):e0223232
PloS one 2019;14(10):e0223232
Hypermethylation Of ADHFE1 Promotes The Proliferation Of Colorectal Cancer Cell Via Modulating Cell Cycle Progression.
Hu YH, Ma S, Zhang XN, Zhang ZY, Zhu HF, Ji YH, Li J, Qian XL, Wang YX
OncoTargets and therapy 2019;12:8105-8115
OncoTargets and therapy 2019;12:8105-8115
The effect of MTHFD2 on the proliferation and migration of colorectal cancer cell lines.
Wei Y, Liu P, Li Q, Du J, Chen Y, Wang Y, Shi H, Wang Y, Zhang H, Xue W, Gao Y, Li D, Feng Y, Yan J, Han J, Zhang J
OncoTargets and therapy 2019;12:6361-6370
OncoTargets and therapy 2019;12:6361-6370
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism.
Chen Z, Lin J, Feng S, Chen X, Huang H, Wang C, Yu Y, He Y, Han S, Zheng L, Huang G
OncoTargets and therapy 2019;12:2397-2408
OncoTargets and therapy 2019;12:2397-2408
Dimethyl fumarate suppresses hepatocellular carcinoma progression via activating SOCS3/JAK1/STAT3 signaling pathway.
Liu H, Feng XD, Yang B, Tong RL, Lu YJ, Chen DY, Zhou L, Xie HY, Zheng SS, Wu J
American journal of translational research 2019;11(8):4713-4725
American journal of translational research 2019;11(8):4713-4725
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
Ma Y, Guan L, Han Y, Zhou Y, Li X, Liu Y, Zhang X, Zhang W, Li X, Wang S, Lu W
Cancer management and research 2019;11:5799-5811
Cancer management and research 2019;11:5799-5811
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Zhang Q, Meng X, Qin G, Xue X, Dang N
Journal of Cancer 2019;10(5):1197-1208
Journal of Cancer 2019;10(5):1197-1208
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
Li X, Fu Y, Xia X, Zhang X, Xiao K, Zhuang X, Zhang Y
Cancer medicine 2019 Sep;8(12):5750-5759
Cancer medicine 2019 Sep;8(12):5750-5759
Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle.
Han Y, Liu C, Zhang D, Men H, Huo L, Geng Q, Wang S, Gao Y, Zhang W, Zhang Y, Jia Z
International journal of oncology 2019 Sep;55(3):629-644
International journal of oncology 2019 Sep;55(3):629-644
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Tian F, Yu C, Wu M, Wu X, Wan L, Zhu X
Cell proliferation 2019 Sep;52(5):e12635
Cell proliferation 2019 Sep;52(5):e12635
Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension.
Wang D, Xu H, Wu B, Jiang S, Pan H, Wang R, Chen J
International journal of molecular medicine 2019 Sep;44(3):871-884
International journal of molecular medicine 2019 Sep;44(3):871-884
NUCKS1 is a novel regulator of milk synthesis in and proliferation of mammary epithelial cells via the mTOR signaling pathway.
Yuan X, Zhang M, Ao J, Zhen Z, Gao X, Li M
Journal of cellular physiology 2019 Sep;234(9):15825-15835
Journal of cellular physiology 2019 Sep;234(9):15825-15835
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, Zhong C
Oncology letters 2019 Sep;18(3):3081-3091
Oncology letters 2019 Sep;18(3):3081-3091
CircNR3C1 inhibits proliferation of bladder cancer cells by sponging miR-27a-3p and downregulating cyclin D1 expression.
Zheng F, Wang M, Li Y, Huang C, Tao D, Xie F, Zhang H, Sun J, Zhang C, Gu C, Wang Z, Jiang G
Cancer letters 2019 Sep 28;460:139-151
Cancer letters 2019 Sep 28;460:139-151
miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells.
Xu X, Chen X, Xu M, Liu X, Pan B, Qin J, Xu T, Zeng K, Pan Y, He B, Sun H, Sun L, Wang S
Aging 2019 Sep 22;11(18):7357-7385
Aging 2019 Sep 22;11(18):7357-7385
Regulation of circadian rhythms by NEAT1 mediated TMAO-induced endothelial proliferation: A protective role of asparagus extract.
Wu X, Chen L, Zeb F, Huang Y, An J, Ren J, Yang F, Feng Q
Experimental cell research 2019 Sep 1;382(1):111451
Experimental cell research 2019 Sep 1;382(1):111451
Resveratrol inhibits the proliferation of estrogen receptor-positive breast cancer cells by suppressing EZH2 through the modulation of ERK1/2 signaling.
Hu C, Liu Y, Teng M, Jiao K, Zhen J, Wu M, Li Z
Cell biology and toxicology 2019 Oct;35(5):445-456
Cell biology and toxicology 2019 Oct;35(5):445-456
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Luo XF, Wu XJ, Wei X, Wang AG, Wang SH, Wang JL
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis.
Gao X, Zhang Y, Zhang R, Zhao Z, Zhang H, Wu J, Shen W, Zhong M
Experimental and therapeutic medicine 2019 Oct;18(4):3062-3070
Experimental and therapeutic medicine 2019 Oct;18(4):3062-3070
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
Li F, Wu JT, Wang PF, Qu LZ
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
Yang J, Zeng Z, Qiao L, Jiang X, Ma J, Wang J, Ye S, Ma Q, Wei J, Wu M, Huang X, Ma D, Gao Q
Molecular cancer research : MCR 2019 Oct;17(10):2015-2028
Molecular cancer research : MCR 2019 Oct;17(10):2015-2028
LXRα-mediated downregulation of EGFR suppress colorectal cancer cell proliferation.
Liang X, Cao Y, Xiang S, Xiang Z
Journal of cellular biochemistry 2019 Oct;120(10):17391-17404
Journal of cellular biochemistry 2019 Oct;120(10):17391-17404
RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
Liu X, Yang Y, Xu C, Yang H, Chen S, Chen H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109377
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109377
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.
Shi Y, Fan S, Wu M, Zuo Z, Li X, Jiang L, Shen Q, Xu P, Zeng L, Zhou Y, Huang Y, Yang Z, Zhou J, Gao J, Zhou H, Xu S, Ji H, Shi P, Wu DD, Yang C, Chen Y
Nature communications 2019 Oct 25;10(1):4892
Nature communications 2019 Oct 25;10(1):4892
O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion.
Han X, Li X, Liu H, Zhang H, Li A, Dong M, Xu Y, Yan B, Sui L, Kong Y
Oncology reports 2019 Nov;42(5):2065-2074
Oncology reports 2019 Nov;42(5):2065-2074
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells.
Wang Z, Zhang M, Shan R, Wang YJ, Chen J, Huang J, Sun LQ, Zhou WB
Oncology reports 2019 Nov;42(5):1915-1923
Oncology reports 2019 Nov;42(5):1915-1923
Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM.
Cheng X, Tan S, Duan F, Yuan Q, Li Q, Deng G
Breast cancer (Tokyo, Japan) 2019 Nov;26(6):766-775
Breast cancer (Tokyo, Japan) 2019 Nov;26(6):766-775
Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway.
Yue G, Chen C, Bai L, Wang G, Huang Y, Wang Y, Cui H, Xiao Y
Molecular medicine reports 2019 Nov;20(5):4551-4557
Molecular medicine reports 2019 Nov;20(5):4551-4557
Agmatinase promotes the lung adenocarcinoma tumorigenesis by activating the NO-MAPKs-PI3K/Akt pathway.
Zhu HE, Yin JY, Chen DX, He S, Chen H
Cell death & disease 2019 Nov 7;10(11):854
Cell death & disease 2019 Nov 7;10(11):854
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
Wang Q, Lv Q, Bian H, Yang L, Guo KL, Ye SS, Dong XF, Tao LL
Cancer medicine 2019 May;8(5):2360-2371
Cancer medicine 2019 May;8(5):2360-2371
piRNA-DQ722010 contributes to prostate hyperplasia of the male offspring mice after the maternal exposed to microcystin-leucine arginine.
Han R, Zhang L, Gan W, Fu K, Jiang K, Ding J, Wu J, Han X, Li D
The Prostate 2019 May;79(7):798-812
The Prostate 2019 May;79(7):798-812
Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia.
Peng W, Tong C, Li L, Huang C, Ran Y, Chen X, Bai Y, Liu Y, Zhao J, Tan B, Luo X, Wang H, Wen L, Zhang C, Zhang H, Ding Y, Qi H, Baker PN
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6327-6338
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6327-6338
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Wu W, He K, Guo Q, Chen J, Zhang M, Huang K, Yang D, Wu L, Deng Y, Luo X, Yu H, Ding Q, Xiang G
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
miR-340-FHL2 axis inhibits cell growth and metastasis in ovarian cancer.
Huang Z, Li Q, Luo K, Zhang Q, Geng J, Zhou X, Xu Y, Qian M, Zhang JA, Ji L, Wu J
Cell death & disease 2019 May 8;10(5):372
Cell death & disease 2019 May 8;10(5):372
MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/β-catenin pathway in acute myeloid leukemia.
Liu B, Ma H, Liu Q, Xiao Y, Pan S, Zhou H, Jia L
Journal of experimental & clinical cancer research : CR 2019 May 16;38(1):200
Journal of experimental & clinical cancer research : CR 2019 May 16;38(1):200
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Yanchun M, Yi W, Lu W, Yu Q, Jian Y, Pengzhou K, Ting Y, Hongyi L, Fang W, Xiaolong C, Yongping C
European journal of pharmacology 2019 May 15;851:43-51
European journal of pharmacology 2019 May 15;851:43-51
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, Zhang B, Sun C, Ning J, Feng L, Zhang H, Ma X
Toxicology and applied pharmacology 2019 May 15;371:63-73
Toxicology and applied pharmacology 2019 May 15;371:63-73
Downregulation of EIF5A2 by miR-221-3p inhibits cell proliferation, promotes cell cycle arrest and apoptosis in medulloblastoma cells.
Yang Y, Cui H, Wang X
Bioscience, biotechnology, and biochemistry 2019 Mar;83(3):400-408
Bioscience, biotechnology, and biochemistry 2019 Mar;83(3):400-408
Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression.
Zhang X, Yang X, Zhu S, Li Q, Zou N
Oncology reports 2019 Mar;41(3):1960-1970
Oncology reports 2019 Mar;41(3):1960-1970
UNBS5162 inhibits SKOV3 ovarian cancer cell proliferation by regulating the PI3K/AKT signalling pathway.
Wang Q, Shi W
Oncology letters 2019 Mar;17(3):2976-2982
Oncology letters 2019 Mar;17(3):2976-2982
A Molecular Targeted Immunotherapeutic Strategy for Ulcerative Colitis via Dual-targeting Nanoparticles Delivering miR-146b to Intestinal Macrophages.
Deng F, He S, Cui S, Shi Y, Tan Y, Li Z, Huang C, Liu D, Zhi F, Peng L
Journal of Crohn's & colitis 2019 Mar 30;13(4):482-494
Journal of Crohn's & colitis 2019 Mar 30;13(4):482-494
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability.
Shen Z, Liao X, Shao Z, Feng M, Yuan J, Wang S, Gan S, Ha Y, He Z, Jie W
BMC cancer 2019 Mar 22;19(1):262
BMC cancer 2019 Mar 22;19(1):262
CORO1C expression is associated with poor survival rates in gastric cancer and promotes metastasis in vitro.
Cheng X, Wang X, Wu Z, Tan S, Zhu T, Ding K
FEBS open bio 2019 Jun;9(6):1097-1108
FEBS open bio 2019 Jun;9(6):1097-1108
A miR-567-PIK3AP1-PI3K/AKT-c-Myc feedback loop regulates tumour growth and chemoresistance in gastric cancer.
Zhang F, Li K, Yao X, Wang H, Li W, Wu J, Li M, Zhou R, Xu L, Zhao L
EBioMedicine 2019 Jun;44:311-321
EBioMedicine 2019 Jun;44:311-321
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
Dong S, Ji J, Hu L, Wang H
Life sciences 2019 Jun 15;227:20-29
Life sciences 2019 Jun 15;227:20-29
Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
Lu GQ, Li XY, Mohamed O K, Wang D, Meng FH
European journal of medicinal chemistry 2019 Jun 1;171:282-296
European journal of medicinal chemistry 2019 Jun 1;171:282-296
IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation.
Zhang W, Lu Y, Li X, Zhang J, Lin W, Zhang W, Zheng L, Li X
Journal of experimental & clinical cancer research : CR 2019 Jul 9;38(1):296
Journal of experimental & clinical cancer research : CR 2019 Jul 9;38(1):296
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
Deng L, Sun J, Chen X, Liu L, Wu D
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
miR-629-5p promotes growth and metastasis of hepatocellular carcinoma by activating β-catenin.
Tao X, Yang X, Wu K, Yang L, Huang Y, Jin Q, Chen S
Experimental cell research 2019 Jul 15;380(2):124-130
Experimental cell research 2019 Jul 15;380(2):124-130
Thyroid hormone (T(3)) is involved in inhibiting the proliferation of newborn calf Sertoli cells via the PI3K/Akt signaling pathway in vitro.
Wang C, Zheng P, Adeniran SO, Ma M, Huang F, Adegoke EO, Zhang G
Theriogenology 2019 Jul 15;133:1-9
Theriogenology 2019 Jul 15;133:1-9
SND1 promotes the proliferation of osteosarcoma cells by upregulating COX‑2/PGE2 expression via activation of NF‑κB.
Zhou M, Wang A, Yin B, Wu D, Han S, Zhang W, Liu J, Sun K
Oncology reports 2019 Jan;41(1):579-589
Oncology reports 2019 Jan;41(1):579-589
Nuclear factor I/B promotes colorectal cancer cell proliferation, epithelial-mesenchymal transition and 5-fluorouracil resistance.
Liu Z, Chen J, Yuan W, Ruan H, Shu Y, Ji J, Wu L, Tang Q, Zhou Z, Zhang X, Cheng Y, He S, Shu X
Cancer science 2019 Jan;110(1):86-98
Cancer science 2019 Jan;110(1):86-98
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Zhang X, Liu J, Gu Y, Sun C, Qu F
Cell biology international 2019 Feb;43(2):158-166
Cell biology international 2019 Feb;43(2):158-166
Regulation of Cell Cycle Regulatory Proteins by MicroRNAs in Uterine Leiomyoma.
Chuang TD, Khorram O
Reproductive sciences (Thousand Oaks, Calif.) 2019 Feb;26(2):250-258
Reproductive sciences (Thousand Oaks, Calif.) 2019 Feb;26(2):250-258
Down-regulation of miR-1181 indicates a dismal prognosis for nasopharyngeal carcinoma and promoted cell proliferation and metastasis by modulating Wnt/β-catenin signaling.
Hua X, Fan KC
European review for medical and pharmacological sciences 2019 Feb;23(3):1077-1086
European review for medical and pharmacological sciences 2019 Feb;23(3):1077-1086
Overexpression of SIRT4 inhibits the proliferation of gastric cancer cells through cell cycle arrest.
Hu Y, Lin J, Lin Y, Chen X, Zhu G, Huang G
Oncology letters 2019 Feb;17(2):2171-2176
Oncology letters 2019 Feb;17(2):2171-2176
JTC-801 inhibits the proliferation and metastasis of the Hep G2 hepatoblastoma cell line by regulating the phosphatidylinositol 3-kinase/protein kinase B signalling pathway.
Zhao B, Hu T
Oncology letters 2019 Feb;17(2):1939-1945
Oncology letters 2019 Feb;17(2):1939-1945
Retracted: Inhibition of microRNA-940 suppresses the migration and invasion of human osteosarcoma cells through the secreted frizzled-related protein 1-mediated Wnt/β-catenin signaling pathway.
Lin ZW, Zhang W, Jiang SD, Wei WB, Li XF
Journal of cellular biochemistry 2019 Feb;120(2):2657-2670
Journal of cellular biochemistry 2019 Feb;120(2):2657-2670
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Zhang Y, Li Q, Yu S, Zhu C, Zhang Z, Cao H, Xu J
Biochemical and biophysical research communications 2019 Feb 12;509(3):753-762
Biochemical and biophysical research communications 2019 Feb 12;509(3):753-762
Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway.
Li T, Xiong Y, Wang Q, Chen F, Zeng Y, Yu X, Wang Y, Zhou F, Zhou Y
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):4001-4011
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):4001-4011
CircCDYL inhibits the expression of C-MYC to suppress cell growth and migration in bladder cancer.
Sun J, Zhang H, Tao D, Xie F, Liu F, Gu C, Wang M, Wang L, Jiang G, Wang Z, Xiao X
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):1349-1356
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):1349-1356
Histone deacetylases inhibitor MS-275 suppresses human esophageal squamous cell carcinoma cell growth and progression via the PI3K/Akt/mTOR pathway.
Ma S, Liu T, Xu L, Wang Y, Zhou J, Huang T, Li P, Liu H, Zhang Y, Zhou X, Cui Y, Zang X, Wang Y, Guan F
Journal of cellular physiology 2019 Dec;234(12):22400-22410
Journal of cellular physiology 2019 Dec;234(12):22400-22410
HOXC13-AS promotes breast cancer cell growth through regulating miR-497-5p/PTEN axis.
Li X, Wang Q, Rui Y, Zhang C, Wang W, Gu J, Tang J, Ding Y
Journal of cellular physiology 2019 Dec;234(12):22343-22351
Journal of cellular physiology 2019 Dec;234(12):22343-22351
MiR-6838-5p suppresses cell metastasis and the EMT process in triple-negative breast cancer by targeting WNT3A to inhibit the Wnt pathway.
Liu G, Wang P, Zhang H
The journal of gene medicine 2019 Dec;21(12):e3129
The journal of gene medicine 2019 Dec;21(12):e3129
MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.
Guan F, Zhou X, Li P, Wang Y, Liu M, Li F, Cui Y, Huang T, Yao M, Zhang Y, Ma J, Ma S
Progress in neuro-psychopharmacology & biological psychiatry 2019 Dec 20;95:109684
Progress in neuro-psychopharmacology & biological psychiatry 2019 Dec 20;95:109684
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
Liu JZ, Hu YL, Feng Y, Guo YB, Liu YF, Yang JL, Mao QS, Xue WJ
Experimental cell research 2019 Dec 15;385(2):111691
Experimental cell research 2019 Dec 15;385(2):111691
LncRNA AC007271.3 promotes cell proliferation, invasion, migration and inhibits cell apoptosis of OSCC via the Wnt/β-catenin signaling pathway.
Shao TR, Zheng ZN, Chen YC, Wu QQ, Huang GZ, Li F, Zeng WS, Lv XZ
Life sciences 2019 Dec 15;239:117087
Life sciences 2019 Dec 15;239:117087
Paper/polymer composited microfluidic platform for screening cell viability and protein expression under a chemical gradient environment.
Lei KF, Goh A, Huang CH
Talanta 2019 Dec 1;205:120124
Talanta 2019 Dec 1;205:120124
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment.
Assani G, Segbo J, Yu X, Yessoufou A, Xiong Y, Zhou F, Zhou Y
Asian Pacific journal of cancer prevention : APJCP 2019 Dec 1;20(12):3679-3687
Asian Pacific journal of cancer prevention : APJCP 2019 Dec 1;20(12):3679-3687
Angiotensin blockade attenuates diabetic nephropathy in hypogonadal adult male rats.
Makary S, Abdo M, Hassan WA, Tawfik MK
Canadian journal of physiology and pharmacology 2019 Aug;97(8):708-720
Canadian journal of physiology and pharmacology 2019 Aug;97(8):708-720
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
(-)-Epicatechin mitigates radiation-induced intestinal injury and promotes intestinal regeneration via suppressing oxidative stress.
Li Y, Ma S, Zhang Y, Yao M, Zhu X, Guan F
Free radical research 2019 Aug;53(8):851-864
Free radical research 2019 Aug;53(8):851-864
RING finger protein 10 is a potential drug target for diabetic vascular complications.
Li S, Yu G, Huang W, Wang R, Pu P, Chen M
Molecular medicine reports 2019 Aug;20(2):931-938
Molecular medicine reports 2019 Aug;20(2):931-938
Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway.
Zheng M, Tian C, Fan T, Xu B
Experimental eye research 2019 Aug;185:107681
Experimental eye research 2019 Aug;185:107681
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Song T, Ma K, Zhao C, Yang J, Liu J
Oncology letters 2019 Aug;18(2):2043-2049
Oncology letters 2019 Aug;18(2):2043-2049
Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer.
Pan JH, Zhou H, Zhu SB, Huang JL, Zhao XX, Ding H, Qin L, Pan YL
Journal of cellular physiology 2019 Apr;234(4):4385-4395
Journal of cellular physiology 2019 Apr;234(4):4385-4395
Enhanced expression of circular RNA hsa_circ_000984 promotes cells proliferation and metastasis in non-small cell lung cancer by modulating Wnt/β-catenin pathway.
Li XY, Liu YR, Zhou JH, Li W, Guo HH, Ma HP
European review for medical and pharmacological sciences 2019 Apr;23(8):3366-3374
European review for medical and pharmacological sciences 2019 Apr;23(8):3366-3374
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, Peng W, Han D, Zhou X, Wu J, He H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo.
Xiong Y, Li T, Assani G, Ling H, Zhou Q, Zeng Y, Zhou F, Zhou Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108602
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108602
Poly(ADP-ribose) Polymerase-1 is required for hepatocyte proliferation and liver regeneration in mice.
Ju C, Liu C, Yan S, Wang Y, Mao X, Liang M, Huang K
Biochemical and biophysical research communications 2019 Apr 9;511(3):531-535
Biochemical and biophysical research communications 2019 Apr 9;511(3):531-535
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
Lin F, Xie YJ, Zhang XK, Huang TJ, Xu HF, Mei Y, Liang H, Hu H, Lin ST, Luo FF, Lang YH, Peng LX, Qian CN, Huang BJ
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
Exogenous biological renal support ameliorates renal pathology after ischemia reperfusion injury in elderly mice.
Liu D, Yin Z, Huang Q, Ren Y, Li D, Wang L, Cui S, Zhang Y, Ning Y, Lun L, Cai G, Bai X, Sun X, Chen X
Aging 2019 Apr 12;11(7):2031-2044
Aging 2019 Apr 12;11(7):2031-2044
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
Li K, Xu X, He Y, Tian Y, Pan W, Xu L, Ma Y, Gao Y, Gao J, Qi Y, Wei L, Zhang J
Journal of Cancer 2018;9(10):1821-1835
Journal of Cancer 2018;9(10):1821-1835
The Long Noncoding RNA 150Rik Promotes Mesangial Cell Proliferation via miR-451/IGF1R/p38 MAPK Signaling in Diabetic Nephropathy.
Zhang Y, Sun Y, Peng R, Liu H, He W, Zhang L, Peng H, Zhang Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(3):1410-1428
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(3):1410-1428
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Wang Y, Tang H, He G, Shi Y, Kang X, Lyu J, Zhou M, Zhu M, Zhang J, Tang K
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
CircRNA8924 Promotes Cervical Cancer Cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8.
Liu J, Wang D, Long Z, Liu J, Li W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(1):173-184
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(1):173-184
Bushenshugan Formula Attenuates the Development of Lung Cancer by Inhibiting Epithelial-Mesenchymal Transition.
Fan Z, Xue W, Dou M, Li L, Lu J, Ma B, Deng X, Zhang M, Zhai Y, Wang S, Zhao J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):1977-1988
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):1977-1988
Down-regulation of long non-coding RNA ITGB2-AS1 inhibits osteosarcoma proliferation and metastasis by repressing Wnt/β-catenin signalling and predicts favourable prognosis.
Dai J, Xu LJ, Han GD, Jiang HT, Sun HL, Zhu GT, Tang XM
Artificial cells, nanomedicine, and biotechnology 2018;46(sup3):S783-S790
Artificial cells, nanomedicine, and biotechnology 2018;46(sup3):S783-S790
Overexpression of Annexin A2 Receptor Inhibits Neovascularization via the Promotion of Krüppel-Like Transcription Factor 2.
Guo T, Song H, Zhao Z, Qi Z, Zhao S
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(4):1617-1627
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(4):1617-1627
SKA3 promotes cell proliferation and migration in cervical cancer by activating the PI3K/Akt signaling pathway.
Hu R, Wang MQ, Niu WB, Wang YJ, Liu YY, Liu LY, Wang M, Zhong J, You HY, Wu XH, Deng N, Lu L, Wei LB
Cancer cell international 2018;18:183
Cancer cell international 2018;18:183
VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2.
Zhao L, Zhu Z, Yao C, Huang Y, Zhi E, Chen H, Tian R, Li P, Yuan Q, Xue Y, Wan Z, Yang C, Gong Y, He Z, Li Z
Cell cycle (Georgetown, Tex.) 2018;17(2):225-239
Cell cycle (Georgetown, Tex.) 2018;17(2):225-239
The protective role of human ghrelin in sepsis: Restoration of CD4 T cell proliferation.
Zhou M, Aziz M, Ochani M, Yang WL, Sharma A, Wang P
PloS one 2018;13(7):e0201139
PloS one 2018;13(7):e0201139
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, Zhang C, Bi Y, Zhang C, Bian H
Chinese medicine 2018;13:17
Chinese medicine 2018;13:17
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Cao S, Chen G, Yan L, Li L, Huang X
OncoTargets and therapy 2018;11:7385-7394
OncoTargets and therapy 2018;11:7385-7394
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Song H, Guo T, Zhao Z, Wei Y, Luo H, Weng W, Zhang R, Zhong M, Chen C, Su J, Shen W
Biomaterials 2018 Sep;178:23-35
Biomaterials 2018 Sep;178:23-35
POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling.
Du Y, Li D, Li N, Su C, Yang C, Lin C, Chen M, Wu R, Li X, Hu G
Cell death & disease 2018 Sep 24;9(10):995
Cell death & disease 2018 Sep 24;9(10):995
LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
Zeng K, Chen X, Hu X, Liu X, Xu T, Sun H, Pan Y, He B, Wang S
Oncogene 2018 Oct;37(41):5534-5551
Oncogene 2018 Oct;37(41):5534-5551
miR-25 Promotes Melanoma Progression by regulating RNA binding motif protein 47.
Jiang QQ, Liu WB
Medecine sciences : M/S 2018 Oct;34 Focus issue F1:59-65
Medecine sciences : M/S 2018 Oct;34 Focus issue F1:59-65
Knockdown of Sox2 Inhibits OS Cells Invasion and Migration via Modulating Wnt/β-Catenin Signaling Pathway.
Tang L, Wang D, Gu D
Pathology oncology research : POR 2018 Oct;24(4):907-913
Pathology oncology research : POR 2018 Oct;24(4):907-913
Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis.
Xie F, Li Y, Wang M, Huang C, Tao D, Zheng F, Zhang H, Zeng F, Xiao X, Jiang G
Molecular cancer 2018 Oct 3;17(1):144
Molecular cancer 2018 Oct 3;17(1):144
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
Yu M, Wang H, Liu J, Qin H, Liu S, Yan Q
FEBS letters 2018 Nov;592(22):3696-3707
FEBS letters 2018 Nov;592(22):3696-3707
MiR-1301-3p inhibits human breast cancer cell proliferation by regulating cell cycle progression and apoptosis through directly targeting ICT1.
Peng X, Yan B, Shen Y
Breast cancer (Tokyo, Japan) 2018 Nov;25(6):742-752
Breast cancer (Tokyo, Japan) 2018 Nov;25(6):742-752
Aclidinium inhibits proliferation and metastasis of ovarian cancer SKOV3 cells via downregulating PI3K/AKT/mTOR signaling pathway.
Qiao J, Wang WJ, Zhang Y
Oncology letters 2018 Nov;16(5):6417-6422
Oncology letters 2018 Nov;16(5):6417-6422
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Yin LL, Wen XM, Li M, Xu YM, Zhao XF, Li J, Wang XW
Oncology letters 2018 Nov;16(5):6283-6292
Oncology letters 2018 Nov;16(5):6283-6292
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Tian T, Sun J, Wang J, Liu Y, Liu H
Oncology letters 2018 Nov;16(5):6133-6139
Oncology letters 2018 Nov;16(5):6133-6139
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Chen X, Liu C, Zhao R, Zhao P, Wu J, Zhou N, Ying M
Molecular pharmaceutics 2018 Nov 5;15(11):4974-4984
Molecular pharmaceutics 2018 Nov 5;15(11):4974-4984
Differential anticancer activities of arsenic trioxide on head and neck cancer cells with different human papillomavirus status.
Du S, Liu K, Gao P, Li Z, Zheng J
Life sciences 2018 Nov 1;212:182-193
Life sciences 2018 Nov 1;212:182-193
Mitochondrial ATAD3A regulates milk biosynthesis and proliferation of mammary epithelial cells from dairy cow via the mTOR pathway.
Chen D, Yuan X, Liu L, Zhang M, Qu B, Zhen Z, Gao X
Cell biology international 2018 May;42(5):533-542
Cell biology international 2018 May;42(5):533-542
Inhibitory effects of aesculetin on the proliferation of colon cancer cells by the Wnt/β-catenin signaling pathway.
Li T, Zhang L, Huo X
Oncology letters 2018 May;15(5):7118-7122
Oncology letters 2018 May;15(5):7118-7122
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
Liu YP, Li L, Xu L, Dai EN, Chen WD
Oncology letters 2018 May;15(5):6527-6532
Oncology letters 2018 May;15(5):6527-6532
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, Geng S, Wu J, Zhong C, Li M
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Journal of cellular biochemistry 2018 May;119(5):4134-4141
The NK1 receptor antagonist NKP608 inhibits proliferation of human colorectal cancer cells via Wnt signaling pathway.
Niu XL, Hou JF, Li JX
Biological research 2018 May 30;51(1):14
Biological research 2018 May 30;51(1):14
MicroRNA-1247 inhibits cell proliferation by directly targeting ZNF346 in childhood neuroblastoma.
Wu T, Lin Y, Xie Z
Biological research 2018 May 24;51(1):13
Biological research 2018 May 24;51(1):13
HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer.
Fu F, Wang T, Wu Z, Feng Y, Wang W, Zhou S, Ma X, Wang S
Cell death & disease 2018 May 22;9(6):594
Cell death & disease 2018 May 22;9(6):594
CCN1/Cyr61 enhances the function of hepatic stellate cells in promoting the progression of hepatocellular carcinoma.
Li ZQ, Wu WR, Zhao C, Zhao C, Zhang XL, Yang Z, Pan J, Si WK
International journal of molecular medicine 2018 Mar;41(3):1518-1528
International journal of molecular medicine 2018 Mar;41(3):1518-1528
Actin-capping protein CapG is associated with prognosis, proliferation and metastasis in human glioma.
Yun DP, Wang YQ, Meng DL, Ji YY, Chen JX, Chen HY, Lu DR
Oncology reports 2018 Mar;39(3):1011-1022
Oncology reports 2018 Mar;39(3):1011-1022
Annexin A2 positively regulates milk synthesis and proliferation of bovine mammary epithelial cells through the mTOR signaling pathway.
Zhang M, Chen D, Zhen Z, Ao J, Yuan X, Gao X
Journal of cellular physiology 2018 Mar;233(3):2464-2475
Journal of cellular physiology 2018 Mar;233(3):2464-2475
Incorporation of Cerium Oxide into Hydroxyapatite Coating Protects Bone Marrow Stromal Cells Against H(2)O(2)-Induced Inhibition of Osteogenic Differentiation.
Li K, Shen Q, Xie Y, You M, Huang L, Zheng X
Biological trace element research 2018 Mar;182(1):91-104
Biological trace element research 2018 Mar;182(1):91-104
Cellular response to persistent foot-and-mouth disease virus infection is linked to specific types of alterations in the host cell transcriptome.
Han L, Xin X, Wang H, Li J, Hao Y, Wang M, Zheng C, Shen C
Scientific reports 2018 Mar 22;8(1):5074
Scientific reports 2018 Mar 22;8(1):5074
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Qian W, Kong X, Zhang T, Wang D, Song J, Li Y, Li X, Geng H, Min J, Kong Q, Liu J, Liu Z, Wang D, Zhang Z, Yu D, Zhong C
Oncogenesis 2018 Mar 13;7(3):24
Oncogenesis 2018 Mar 13;7(3):24
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Zhang Q, Li XT, Chen Y, Chen JQ, Zhu JY, Meng Y, Wang XQ, Li Y, Geng SS, Xie CF, Wu JS, Zhong CY, Han HY
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
Jia W, Jiang X, Liu W, Wang L, Zhu B, Zhu H, Liu X, Zhong M, Xie D, Huang W, Jia W, Li S, Liu X, Zuo X, Cheng D, Dai J, Ren C
International journal of oncology 2018 Jun;52(6):1787-1800
International journal of oncology 2018 Jun;52(6):1787-1800
MicroRNA-384 inhibits the progression of breast cancer by targeting ACVR1.
Wang Y, Zhang Z, Wang J
Oncology reports 2018 Jun;39(6):2563-2574
Oncology reports 2018 Jun;39(6):2563-2574
Curcumin-Loaded Solid Lipid Nanoparticles Enhanced Anticancer Efficiency in Breast Cancer.
Wang W, Chen T, Xu H, Ren B, Cheng X, Qi R, Liu H, Wang Y, Yan L, Chen S, Yang Q, Chen C
Molecules (Basel, Switzerland) 2018 Jun 29;23(7)
Molecules (Basel, Switzerland) 2018 Jun 29;23(7)
NF-κB and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.
Zeng GZ, Wang Z, Zhao LM, Fan JT, Tan NH
Journal of ethnopharmacology 2018 Jun 28;220:220-227
Journal of ethnopharmacology 2018 Jun 28;220:220-227
LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial-mesenchymal transition through the Notch1 signaling pathway.
Liu W, Zhang J, Gan X, Shen F, Yang X, Du N, Xia D, Liu L, Qiao L, Pan J, Sun Y, Xi X
Cancer medicine 2018 Jul;7(7):3132-3142
Cancer medicine 2018 Jul;7(7):3132-3142
DEAD-box helicase 6 (DDX6) is a new negative regulator for milk synthesis and proliferation of bovine mammary epithelial cells.
Zhen Z, Zhang M, Yuan X, Qu B, Yu Y, Gao X, Qiu Y
In vitro cellular & developmental biology. Animal 2018 Jan;54(1):52-60
In vitro cellular & developmental biology. Animal 2018 Jan;54(1):52-60
High expression of TMEM40 is associated with the malignant behavior and tumorigenesis in bladder cancer.
Zhang ZF, Zhang HR, Zhang QY, Lai SY, Feng YZ, Zhou Y, Zheng SR, Shi R, Zhou JY
Journal of translational medicine 2018 Jan 19;16(1):9
Journal of translational medicine 2018 Jan 19;16(1):9
Involvement of mitochondrial fission in calcium sensing receptor-mediated vascular smooth muscle cells proliferation during hypertension.
Zhang X, Chen W, Li J, Qi S, Hong S, Wang Y, Gao L, Shi Z, Liu Y, Liu W, Chi Y, Liu C, Fu Y, Yin X
Biochemical and biophysical research communications 2018 Jan 1;495(1):454-460
Biochemical and biophysical research communications 2018 Jan 1;495(1):454-460
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Xiao Y, Tian C, Huang T, Han B, Wang M, Ma H, Li Z, Ye X, Li X
Life sciences 2018 Jan 1;192:259-269
Life sciences 2018 Jan 1;192:259-269
Vascular peroxidase 1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation, apoptosis resistance and migration.
You B, Liu Y, Chen J, Huang X, Peng H, Liu Z, Tang Y, Zhang K, Xu Q, Li X, Cheng G, Shi R, Zhang G
Cardiovascular research 2018 Jan 1;114(1):188-199
Cardiovascular research 2018 Jan 1;114(1):188-199
YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury.
Deng F, Peng L, Li Z, Tan G, Liang E, Chen S, Zhao X, Zhi F
Cell death & disease 2018 Feb 2;9(2):153
Cell death & disease 2018 Feb 2;9(2):153
PTBP3 splicing factor promotes hepatocellular carcinoma by destroying the splicing balance of NEAT1 and pre-miR-612.
Yang X, Qu S, Wang L, Zhang H, Yang Z, Wang J, Dai B, Tao K, Shang R, Liu Z, Li X, Zhang Z, Xia C, Ma B, Liu W, Li H, Dou K
Oncogene 2018 Dec;37(50):6399-6413
Oncogene 2018 Dec;37(50):6399-6413
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Chen Y, Li Y, Wang XQ, Meng Y, Zhang Q, Zhu JY, Chen JQ, Cao WS, Wang XQ, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway.
Liu B, Xu L, Dai EN, Tian JX, Li JM
Bioscience reports 2018 Dec 21;38(6)
Bioscience reports 2018 Dec 21;38(6)
Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.
Li K, Ma YB, Zhang Z, Tian YH, Xu XL, He YQ, Xu L, Gao Y, Pan WT, Song WJ, He X, Wei L
Cancer medicine 2018 Aug;7(8):3875-3888
Cancer medicine 2018 Aug;7(8):3875-3888
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
Yu Z, Tian X, Peng Y, Sun Z, Wang C, Tang N, Li B, Jian Y, Wang W, Huo X, Ma X
Journal of pineal research 2018 Aug;65(1):e12478
Journal of pineal research 2018 Aug;65(1):e12478
Resveratrol inhibits the growth of gastric cancer via the Wnt/β-catenin pathway.
Dai H, Deng HB, Wang YH, Guo JJ
Oncology letters 2018 Aug;16(2):1579-1583
Oncology letters 2018 Aug;16(2):1579-1583
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
Meng M, Chen Y, Jia J, Li L, Yang S
Biological research 2018 Aug 10;51(1):24
Biological research 2018 Aug 10;51(1):24
Telmisartan inhibits NSCLC A549 cell proliferation and migration by regulating the PI3K/AKT signaling pathway.
Zhang S, Wang Y
Oncology letters 2018 Apr;15(4):5859-5864
Oncology letters 2018 Apr;15(4):5859-5864
Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade.
Lu QB, Wan MY, Wang PY, Zhang CX, Xu DY, Liao X, Sun HJ
Redox biology 2018 Apr;14:656-668
Redox biology 2018 Apr;14:656-668
MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation.
Ren T, Wang J, Zhang H, Yuan P, Zhu J, Wu Y, Huang Q, Guo X, Zhang J, Ji L, Li J, Zhang H, Yang H, Xing J
Antioxidants & redox signaling 2018 Apr 20;28(12):1120-1136
Antioxidants & redox signaling 2018 Apr 20;28(12):1120-1136
Androgen Receptor Is Inactivated and Degraded in Bladder Cancer Cells by Phenyl Glucosamine via miR-449a Restoration.
Guo J, Hu J, Cao R, Chen Q, Li K
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 16;24:2294-2301
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 16;24:2294-2301
Anticancer effect of PP31J isolated from Physalis pubescens L. in human cervical carcinoma cells.
Zeng W, Wang Q, Chen L, Huang L, Zhao X
American journal of translational research 2017;9(5):2466-2472
American journal of translational research 2017;9(5):2466-2472
Histone deacetylase inhibitor NaBut suppresses cell proliferation and induces apoptosis by targeting p21 in multiple myeloma.
Yao R, Han D, Sun X, Fu C, Wu Q, Yao Y, Li H, Li Z, Xu K
American journal of translational research 2017;9(11):4994-5002
American journal of translational research 2017;9(11):4994-5002
Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.
Wang Y, He T, Herman JG, Linghu E, Yang Y, Fuks F, Zhou F, Song L, Guo M
Clinical epigenetics 2017;9:115
Clinical epigenetics 2017;9:115
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Yang HF, Yu M, Jin HD, Yao JQ, Lu ZL, Yabasin IB, Yan Q, Wen QP
Frontiers in physiology 2017;8:510
Frontiers in physiology 2017;8:510
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer.
Wei WJ, Sun ZK, Shen CT, Song HJ, Zhang XY, Qiu ZL, Luo QY
Theranostics 2017;7(4):987-1001
Theranostics 2017;7(4):987-1001
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Sun W, Yang J, Zhang Y, Xi Y, Wen X, Yuan D, Wang Y, Wei C, Wang R, Wu L, Li H, Xu C
Cell & bioscience 2017;7:67
Cell & bioscience 2017;7:67
Therapy Effects of Wogonin on Ovarian Cancer Cells.
Ruibin J, Bo J, Danying W, Chihong Z, Jianguo F, Linhui G
BioMed research international 2017;2017:9381513
BioMed research international 2017;2017:9381513
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
Wang B, Shen J, Wang J
OncoTargets and therapy 2017;10:5303-5309
OncoTargets and therapy 2017;10:5303-5309
CDKL1 promotes tumor proliferation and invasion in colorectal cancer.
Qin C, Ren L, Ji M, Lv S, Wei Y, Zhu D, Lin Q, Xu P, Chang W, Xu J
OncoTargets and therapy 2017;10:1613-1624
OncoTargets and therapy 2017;10:1613-1624
Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer.
Zhang B, Liu Y, Liu D, Yang L
Journal of biosciences 2017 Sep;42(3):417-425
Journal of biosciences 2017 Sep;42(3):417-425
Mono-ADP-ribosylation of histone 3 at arginine-117 promotes proliferation through its interaction with P300.
Ling F, Tang Y, Li M, Li QS, Li X, Yang L, Zhao W, Jin CC, Zeng Z, Liu C, Wu CF, Chen WW, Lin X, Wang YL, Threadgill MD
Oncotarget 2017 Sep 22;8(42):72773-72787
Oncotarget 2017 Sep 22;8(42):72773-72787
Salusin-β mediates high glucose-induced endothelial injury via disruption of AMPK signaling pathway.
Zhu X, Zhou Y, Cai W, Sun H, Qiu L
Biochemical and biophysical research communications 2017 Sep 16;491(2):515-521
Biochemical and biophysical research communications 2017 Sep 16;491(2):515-521
Knockdown of tripartite motif-59 inhibits the malignant processes in human colorectal cancer cells.
Wu W, Chen J, Wu J, Lin J, Yang S, Yu H
Oncology reports 2017 Oct;38(4):2480-2488
Oncology reports 2017 Oct;38(4):2480-2488
Knockdown of Immature Colon Carcinoma Transcript 1 Inhibits Proliferation and Promotes Apoptosis of Non-Small Cell Lung Cancer Cells.
Wang Y, He J, Zhang S, Yang Q, Wang B, Liu Z, Wu X
Technology in cancer research & treatment 2017 Oct;16(5):559-569
Technology in cancer research & treatment 2017 Oct;16(5):559-569
EDIL3 knockdown inhibits retinal angiogenesis through the induction of cell cycle arrest in vitro.
Shen W, Zhu S, Qin H, Zhong M, Wu J, Zhang R, Song H
Molecular medicine reports 2017 Oct;16(4):4054-4060
Molecular medicine reports 2017 Oct;16(4):4054-4060
Downregulation of Cohesin Loading Factor Nipped-B-Like Protein (NIPBL) Induces Cell Cycle Arrest, Apoptosis, and Autophagy of Breast Cancer Cell Lines.
Zhou H, Zheng L, Lu K, Gao Y, Guo L, Xu W, Wang X
Medical science monitor : international medical journal of experimental and clinical research 2017 Oct 7;23:4817-4825
Medical science monitor : international medical journal of experimental and clinical research 2017 Oct 7;23:4817-4825
Twinfilin 1 enhances milk bio-synthesis and proliferation of bovine mammary epithelial cells via the mTOR signaling pathway.
Li L, Liu L, Qu B, Li X, Gao X, Zhang M
Biochemical and biophysical research communications 2017 Oct 21;492(3):289-294
Biochemical and biophysical research communications 2017 Oct 21;492(3):289-294
Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma.
Lin B, Zhou X, Lin S, Wang X, Zhang M, Cao B, Dong Y, Yang S, Wang JM, Guo M, Huang J
Journal of molecular medicine (Berlin, Germany) 2017 Nov;95(11):1237-1249
Journal of molecular medicine (Berlin, Germany) 2017 Nov;95(11):1237-1249
DLEU1 contributes to ovarian carcinoma tumourigenesis and development by interacting with miR-490-3p and altering CDK1 expression.
Wang LL, Sun KX, Wu DD, Xiu YL, Chen X, Chen S, Zong ZH, Sang XB, Liu Y, Zhao Y
Journal of cellular and molecular medicine 2017 Nov;21(11):3055-3065
Journal of cellular and molecular medicine 2017 Nov;21(11):3055-3065
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, Yu D, Zhong C
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Fascaplysin inhibit ovarian cancer cell proliferation and metastasis through inhibiting CDK4.
Chen S, Guan X, Wang LL, Li B, Sang XB, Liu Y, Zhao Y
Gene 2017 Nov 30;635:3-8
Gene 2017 Nov 30;635:3-8
MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication.
Zheng C, Zheng Z, Sun J, Zhang Y, Wei C, Ke X, Liu Y, Deng L, Wang H
Scientific reports 2017 Nov 27;7(1):16422
Scientific reports 2017 Nov 27;7(1):16422
(-)-Curine induces cell cycle arrest and cell death in hepatocellular carcinoma cells in a p53-independent way.
Gong S, Xu D, Zou F, Peng R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:894-901
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:894-901
The transcription factor FOXA1 induces epithelial ovarian cancer tumorigenesis and progression.
Wang LL, Xiu YL, Chen X, Sun KX, Chen S, Wu DD, Liu BL, Zhao Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317706210
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317706210
The soy-derived peptide Vglycin inhibits the growth of colon cancer cells in vitro and in vivo.
Gao C, Sun R, Xie YR, Jiang AL, Lin M, Li M, Chen ZW, Zhang P, Jin H, Feng JP
Experimental biology and medicine (Maywood, N.J.) 2017 May;242(10):1034-1043
Experimental biology and medicine (Maywood, N.J.) 2017 May;242(10):1034-1043
High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling.
He S, Zhong W, Yin L, Wang Y, Qiu Z, Song G
Molecular medicine reports 2017 May;15(5):2567-2573
Molecular medicine reports 2017 May;15(5):2567-2573
Involvement of the activation of Nrf2/HO-1, p38 MAPK signaling pathways and endoplasmic reticulum stress in furazolidone induced cytotoxicity and S phase arrest in human hepatocyte L02 cells: modulation of curcumin.
Dai C, Lei L, Li B, Lin Y, Xiao X, Tang S
Toxicology mechanisms and methods 2017 Mar;27(3):165-172
Toxicology mechanisms and methods 2017 Mar;27(3):165-172
miR-491-5p, mediated by Foxi1, functions as a tumor suppressor by targeting Wnt3a/β-catenin signaling in the development of gastric cancer.
Sun R, Liu Z, Tong D, Yang Y, Guo B, Wang X, Zhao L, Huang C
Cell death & disease 2017 Mar 30;8(3):e2714
Cell death & disease 2017 Mar 30;8(3):e2714
Correlations between TBL1XR1 and recurrence of colorectal cancer.
Liu H, Xu Y, Zhang Q, Li K, Wang D, Li S, Ning S, Yang H, Shi W, Liu Z, Chen Y
Scientific reports 2017 Mar 15;7:44275
Scientific reports 2017 Mar 15;7:44275
Methylation of SLFN11 is a marker of poor prognosis and cisplatin resistance in colorectal cancer.
He T, Zhang M, Zheng R, Zheng S, Linghu E, Herman JG, Guo M
Epigenomics 2017 Jun;9(6):849-862
Epigenomics 2017 Jun;9(6):849-862
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, Li Y, Wang X, Meng Y, Zhu M, Ma X, Huang C, Wu R, Xie C, Geng S, Wu J, Zhong C, Han H
The Journal of nutritional biochemistry 2017 Jun;44:80-91
The Journal of nutritional biochemistry 2017 Jun;44:80-91
ω-3 free fatty acids and all-trans retinoic acid synergistically induce growth inhibition of three subtypes of breast cancer cell lines.
Lin G, Zhu S, Wu Y, Song C, Wang W, Zhang Y, Chen YL, He Z
Scientific reports 2017 Jun 7;7(1):2929
Scientific reports 2017 Jun 7;7(1):2929
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Chen Y, Wang XQ, Zhang Q, Zhu JY, Li Y, Xie CF, Li XT, Wu JS, Geng SS, Zhong CY, Han HY
Nutrients 2017 Jun 3;9(6)
Nutrients 2017 Jun 3;9(6)
Methylation of DACT2 promotes breast cancer development by activating Wnt signaling.
Li J, Zhang M, He T, Li H, Cao T, Zheng L, Guo M
Scientific reports 2017 Jun 12;7(1):3325
Scientific reports 2017 Jun 12;7(1):3325
Effects of digoxin on cell cycle, apoptosis and NF-κB pathway in Burkitt's lymphoma cells and animal model.
Wang T, Xu P, Wang F, Zhou D, Wang R, Meng L, Wang X, Zhou M, Chen B, Ouyang J
Leukemia & lymphoma 2017 Jul;58(7):1673-1685
Leukemia & lymphoma 2017 Jul;58(7):1673-1685
Estrogen receptor-α36 is involved in icaritin induced growth inhibition of triple-negative breast cancer cells.
Wang X, Zheng N, Dong J, Wang X, Liu L, Huang J
The Journal of steroid biochemistry and molecular biology 2017 Jul;171:318-327
The Journal of steroid biochemistry and molecular biology 2017 Jul;171:318-327
Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.
Sheng X, You Q, Zhu H, Chang Z, Li Q, Wang H, Wang C, Wang H, Hui L, Du C, Xie X, Zeng R, Lin A, Shi D, Ruan K, Yan J, Gao GF, Shao F, Hu R
PLoS pathogens 2017 Jul;13(7):e1006534
PLoS pathogens 2017 Jul;13(7):e1006534
Dalbinol, a rotenoid from Amorpha fruticosa L., exerts anti-proliferative activity by facilitating β-catenin degradation in hepatocellular carcinoma cells.
Zhu X, Wu X, Cheng J, Liao H, Di X, Li L, Li R, Zhou Y, Zhang X
Oncotarget 2017 Jul 18;8(29):47755-47766
Oncotarget 2017 Jul 18;8(29):47755-47766
Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.
Hu YH, Chen Q, Lu YX, Zhang JM, Lin C, Zhang F, Zhang WJ, Li XM, Zhang W, Li XN
Oncotarget 2017 Jul 11;8(28):46191-46203
Oncotarget 2017 Jul 11;8(28):46191-46203
Galangin suppresses human osteosarcoma cells: An exploration of its underlying mechanism.
Yang Z, Li X, Han W, Lu X, Jin S, Yang W, Li J, He W, Qian Y
Oncology reports 2017 Jan;37(1):435-441
Oncology reports 2017 Jan;37(1):435-441
H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells.
Zhang Y, Xu C, Gu D, Wu M, Yan B, Xu Z, Wang Y, Liu H
Stem cells (Dayton, Ohio) 2017 Jan;35(1):222-235
Stem cells (Dayton, Ohio) 2017 Jan;35(1):222-235
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Yang J, Qiao L, Zeng Z, Wang J, Zhu T, Wei J, Wu M, Ye S, Huang X, Ma D, Liu R, Gao Q
Toxicology letters 2017 Jan 4;265:131-139
Toxicology letters 2017 Jan 4;265:131-139
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
Xue C, Wang C, Sun Y, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Ma X, Peng J, Liu K
Oncotarget 2017 Jan 31;8(5):8622-8632
Oncotarget 2017 Jan 31;8(5):8622-8632
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
Mao X, Li P, Wang Y, Liang Z, Liu J, Li J, Jiang Y, Bao G, Li L, Zhu B, Ren Y, Zhao X, Zhang J, Liu Y, Yang J, Liu P
Cell death & disease 2017 Jan 12;8(1):e2546
Cell death & disease 2017 Jan 12;8(1):e2546
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, Li Y, Chen Y, Wang X, Meng Y, Zhu M, Wu R, Huang C, Ma X, Geng S, Wu J, Zhong C
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Huang T, Xiao Y, Yi L, Li L, Wang M, Tian C, Ma H, He K, Wang Y, Han B, Ye X, Li X
Scientific reports 2017 Feb 6;7:38524
Scientific reports 2017 Feb 6;7:38524
Circular RNA 0000096 affects cell growth and migration in gastric cancer.
Li P, Chen H, Chen S, Mo X, Li T, Xiao B, Yu R, Guo J
British journal of cancer 2017 Feb 28;116(5):626-633
British journal of cancer 2017 Feb 28;116(5):626-633
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway.
Zang MD, Hu L, Fan ZY, Wang HX, Zhu ZL, Cao S, Wu XY, Li JF, Su LP, Li C, Zhu ZG, Yan M, Liu BY
Journal of translational medicine 2017 Feb 27;15(1):52
Journal of translational medicine 2017 Feb 27;15(1):52
Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells.
Liang Z, Li W, Liu J, Li J, He F, Jiang Y, Yang L, Li P, Wang B, Wang Y, Ren Y, Yang J, Luo Z, Vaziri C, Liu P
Scientific reports 2017 Feb 2;7:41776
Scientific reports 2017 Feb 2;7:41776
TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway.
Xu G, Guo Y, Xu D, Wang Y, Shen Y, Wang F, Lv Y, Song F, Jiang D, Zhang Y, Lou Y, Meng Y, Yang Y, Kang Y
Scientific reports 2017 Feb 16;7:42411
Scientific reports 2017 Feb 16;7:42411
Rhodium (II) complex with 2-benzoylpyridine, a novel potential chemotherapeutic drug, induces cell cycle arrest and apoptosis in HepG2 cells.
Wang X, Li Y, Lin M, Jin J, Huang Z
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2017 Dec;30(6):903-915
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2017 Dec;30(6):903-915
MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling.
Tang H, Lei CT, Ye C, Gao P, Wan C, Chen S, He FF, Wang YM, Su H, Zhang C
Journal of cellular and molecular medicine 2017 Dec;21(12):3435-3444
Journal of cellular and molecular medicine 2017 Dec;21(12):3435-3444
GRP78 positively regulates estrogen‑stimulated cell growth mediated by ER‑α36 in gastric cancer cells.
Fu Z, Wang X, Zhou H, Li Y, Chen Y, Wang Z, Liu L
Molecular medicine reports 2017 Dec;16(6):8329-8334
Molecular medicine reports 2017 Dec;16(6):8329-8334
Knockdown of Rhotekin 2 expression suppresses proliferation and induces apoptosis in colon cancer cells.
Pang X, Li R, Shi D, Pan X, Ma C, Zhang G, Mu C, Chen W
Oncology letters 2017 Dec;14(6):8028-8034
Oncology letters 2017 Dec;14(6):8028-8034
Shrimp miR-34 from Shrimp Stress Response to Virus Infection Suppresses Tumorigenesis of Breast Cancer.
Cui Y, Yang X, Zhang X
Molecular therapy. Nucleic acids 2017 Dec 15;9:387-398
Molecular therapy. Nucleic acids 2017 Dec 15;9:387-398
Effects of high-intensity focused ultrasound on cisplatin-resistant human lung adenocarcinoma in vitro and in vivo.
Zhang T, Chen L, Zhang S, Xu Y, Fan Y, Zhang L
Acta biochimica et biophysica Sinica 2017 Dec 1;49(12):1092-1098
Acta biochimica et biophysica Sinica 2017 Dec 1;49(12):1092-1098
Downregulation of USP32 inhibits cell proliferation, migration and invasion in human small cell lung cancer.
Hu W, Wei H, Li K, Li P, Lin J, Feng R
Cell proliferation 2017 Aug;50(4)
Cell proliferation 2017 Aug;50(4)
Fangchinoline suppresses the proliferation, invasion and tumorigenesis of human osteosarcoma cells through the inhibition of PI3K and downstream signaling pathways.
Li X, Yang Z, Han W, Lu X, Jin S, Yang W, Li J, He W, Qian Y
International journal of molecular medicine 2017 Aug;40(2):311-318
International journal of molecular medicine 2017 Aug;40(2):311-318
Efficient expression of stable recombinant human insulin-like growth factor-1 fusion with human serum albumin in Chinese hamster ovary cells.
Wan A, Xu D, Liu K, Peng L, Cai Y, Chen Y, He Y, Yang J, Jin J, Li H
Preparative biochemistry & biotechnology 2017 Aug 9;47(7):678-686
Preparative biochemistry & biotechnology 2017 Aug 9;47(7):678-686
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
Sun HJ, Xu DY, Sun YX, Xue T, Zhang CX, Zhang ZX, Lin W, Li KX
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
GOLPH3 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in epithelial ovarian cancer.
Sun J, Yang X, Zhang R, Liu S, Gan X, Xi X, Zhang Z, Feng Y, Sun Y
Cancer medicine 2017 Apr;6(4):834-844
Cancer medicine 2017 Apr;6(4):834-844
The role of MIF, cyclinD1 and ERK in the development of pulmonary hypertension in broilers.
Li H, Wang Y, Chen L, Han L, Li L, He H, Li Y, Huang N, Ren H, Pei F, Li G, Cheng J, Wang W
Avian pathology : journal of the W.V.P.A 2017 Apr;46(2):202-208
Avian pathology : journal of the W.V.P.A 2017 Apr;46(2):202-208
Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.
Quan Z, He Y, Luo C, Xia Y, Zhao Y, Liu N, Wu X
Cellular signalling 2017 Apr;32:48-58
Cellular signalling 2017 Apr;32:48-58
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Zhu JY, Yang X, Chen Y, Jiang Y, Wang SJ, Li Y, Wang XQ, Meng Y, Zhu MM, Ma X, Huang C, Wu R, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Phytotherapy research : PTR 2017 Apr;31(4):680-688
GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis.
Wang X, Liu B, Xu Q, Sun H, Shi M, Wang D, Guo M, Yu J, Zhao C, Feng B
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2017 Apr;25(2):270-278
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2017 Apr;25(2):270-278
The Antitumor Effect of DYC-279 on Human Hepatocellular Carcinoma HepG2 Cells.
Junyan P, Shujuan Y, Shulin G, Yan C, Xia X
Pharmacology 2016;97(3-4):177-83
Pharmacology 2016;97(3-4):177-83
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Wang D, Wang D, Wang N, Long Z, Ren X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer.
Chen S, Sun KX, Feng MX, Sang XB, Liu BL, Zhao Y
Drug design, development and therapy 2016;10:1225-32
Drug design, development and therapy 2016;10:1225-32
Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib.
Wei WJ, Shen CT, Song HJ, Qiu ZL, Luo QY
Oncology reports 2016 Sep;36(3):1576-84
Oncology reports 2016 Sep;36(3):1576-84
Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway.
Feng T, Zheng L, Liu F, Xu X, Mao S, Wang X, Liu J, Lu Y, Zhao W, Yu X, Tang W
Oncotarget 2016 Sep 6;7(36):58381-58395
Oncotarget 2016 Sep 6;7(36):58381-58395
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Wang Y, Zhang XN, Xie WH, Zheng YX, Cao JP, Cao PR, Chen QJ, Li X, Sun CD
Nutrients 2016 Sep 27;8(10)
Nutrients 2016 Sep 27;8(10)
Knockdown of USP39 induces cell cycle arrest and apoptosis in melanoma.
Zhao Y, Zhang B, Lei Y, Sun J, Zhang Y, Yang S, Zhang X
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):13167-13176
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):13167-13176
Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma.
Zhan L, Cao H, Wang G, Lyu Y, Sun X, An J, Wu Z, Huang Q, Liu B, Xing J
Oncotarget 2016 Oct 4;7(40):65001-65011
Oncotarget 2016 Oct 4;7(40):65001-65011
Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance.
Zhao Y, Huan ML, Liu M, Cheng Y, Sun Y, Cui H, Liu DZ, Mei QB, Zhou SY
Scientific reports 2016 Oct 12;6:35267
Scientific reports 2016 Oct 12;6:35267
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Yuan S, Wen J, Cheng J, Shen W, Zhou S, Yan W, Shen L, Luo A, Wang S
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
Li H, Zhou F, Du W, Dou J, Xu Y, Gao W, Chen G, Zuo X, Sun L, Zhang X, Yang S
Biotechnology and applied biochemistry 2016 May;63(3):328-33
Biotechnology and applied biochemistry 2016 May;63(3):328-33
LSD1 is Required for Hair Cell Regeneration in Zebrafish.
He Y, Tang D, Cai C, Chai R, Li H
Molecular neurobiology 2016 May;53(4):2421-34
Molecular neurobiology 2016 May;53(4):2421-34
The effects of the 5-HT2A receptor antagonist sarpogrelate hydrochloride on chronic hypoxic pulmonary hypertension in rats.
Geng J, Fan FL, He S, Liu Y, Meng Y, Tian H, Zhang D, Ma Q, Zhang JB, Tian HY
Experimental lung research 2016 May;42(4):190-8
Experimental lung research 2016 May;42(4):190-8
The AhR is involved in the regulation of LoVo cell proliferation through cell cycle-associated proteins.
Yin J, Sheng B, Han B, Pu A, Yang K, Li P, Wang Q, Xiao W, Yang H
Cell biology international 2016 May;40(5):560-8
Cell biology international 2016 May;40(5):560-8
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Chen S, Sun KX, Liu BL, Zong ZH, Zhao Y
Oncotarget 2016 May 10;7(19):27538-51
Oncotarget 2016 May 10;7(19):27538-51
Down-regulation of dihydrofolate reductase inhibits the growth of endothelial EA.hy926 cell through induction of G1 cell cycle arrest via up-regulating p53 and p21(waf1/cip1) expression.
Fei Z, Gao Y, Qiu M, Qi X, Dai Y, Wang S, Quan Z, Liu Y, Ou J
Journal of clinical biochemistry and nutrition 2016 Mar;58(2):105-13
Journal of clinical biochemistry and nutrition 2016 Mar;58(2):105-13
miR-194 inhibits the proliferation, invasion, migration, and enhances the chemosensitivity of non-small cell lung cancer cells by targeting forkhead box A1 protein.
Zhu X, Li D, Yu F, Jia C, Xie J, Ma Y, Fan S, Cai H, Luo Q, Lv Z, Fan L
Oncotarget 2016 Mar 15;7(11):13139-52
Oncotarget 2016 Mar 15;7(11):13139-52
MicroRNA-655-3p functions as a tumor suppressor by regulating ADAM10 and β-catenin pathway in Hepatocellular Carcinoma.
Wu G, Zheng K, Xia S, Wang Y, Meng X, Qin X, Cheng Y
Journal of experimental & clinical cancer research : CR 2016 Jun 4;35(1):89
Journal of experimental & clinical cancer research : CR 2016 Jun 4;35(1):89
The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR.
Zhao S, Cao Y, Liu SB, Wang XA, Bao RF, Shu YJ, Hu YP, Zhang YJ, Jiang L, Zhang F, Liang HB, Li HF, Ma Q, Xu Y, Wang Z, Zhang YC, Chen L, Zhou J, Liu YB
Journal of experimental & clinical cancer research : CR 2016 Jun 18;35(1):97
Journal of experimental & clinical cancer research : CR 2016 Jun 18;35(1):97
Latcripin-13 domain induces apoptosis and cell cycle arrest at the G1 phase in human lung carcinoma A549 cells.
Wang J, Wan X, Gao Y, Zhong M, Sha L, Liu B, Zhang W, Tian L, Ruan W, Cao S, Huang M
Oncology reports 2016 Jul;36(1):441-7
Oncology reports 2016 Jul;36(1):441-7
High Expression of XRCC6 Promotes Human Osteosarcoma Cell Proliferation through the β-Catenin/Wnt Signaling Pathway and Is Associated with Poor Prognosis.
Zhu B, Cheng D, Li S, Zhou S, Yang Q
International journal of molecular sciences 2016 Jul 22;17(7)
International journal of molecular sciences 2016 Jul 22;17(7)
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway.
Zhang J, Wen X, Ren XY, Li YQ, Tang XR, Wang YQ, He QM, Yang XJ, Sun Y, Liu N, Ma J
Journal of experimental & clinical cancer research : CR 2016 Jul 11;35(1):109
Journal of experimental & clinical cancer research : CR 2016 Jul 11;35(1):109
GalNAc-T4 putatively modulates the estrogen regulatory network through FOXA1 glycosylation in human breast cancer cells.
Niang B, Jin L, Chen X, Guo X, Zhang H, Wu Q, Padhiar AA, Xiao M, Fang D, Zhang J
Molecular and cellular biochemistry 2016 Jan;411(1-2):393-402
Molecular and cellular biochemistry 2016 Jan;411(1-2):393-402
Keratinocyte Growth Factor Regulation of Aryl Hydrocarbon Receptor Activation in Colorectal Cancer Cells.
Yin J, Sheng B, Pu A, Han B, Yang K, Wang Q, Sun L, Yang H
Digestive diseases and sciences 2016 Feb;61(2):444-52
Digestive diseases and sciences 2016 Feb;61(2):444-52
miRNA-149* promotes cell proliferation and suppresses apoptosis by mediating JunB in T-cell acute lymphoblastic leukemia.
Fan SJ, Li HB, Cui G, Kong XL, Sun LL, Zhao YQ, Li YH, Zhou J
Leukemia research 2016 Feb;41:62-70
Leukemia research 2016 Feb;41:62-70
MicroRNA-101 targets von Hippel-Lindau tumor suppressor (VHL) to induce HIF1α mediated apoptosis and cell cycle arrest in normoxia condition.
Liu N, Xia WY, Liu SS, Chen HY, Sun L, Liu MY, Li LF, Lu HM, Fu YJ, Wang P, Wu H, Gao JX
Scientific reports 2016 Feb 4;6:20489
Scientific reports 2016 Feb 4;6:20489
Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma.
Wang XQ, Tang ZX, Yu D, Cui SJ, Jiang YH, Zhang Q, Wang J, Yang PY, Liu F
Oncotarget 2016 Feb 23;7(8):8823-38
Oncotarget 2016 Feb 23;7(8):8823-38
Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling.
Liu F, Zhang W, Yang F, Feng T, Zhou M, Yu Y, Yu X, Zhao W, Yi F, Tang W, Lu Y
Scientific reports 2016 Feb 16;6:21260
Scientific reports 2016 Feb 16;6:21260
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway.
Gao H, Sun B, Fu H, Chi X, Wang F, Qi X, Hu J, Shao S
Oncotarget 2016 Aug 16;7(33):53289-53298
Oncotarget 2016 Aug 16;7(33):53289-53298
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Geng S, Zheng Y, Meng M, Guo Z, Cao N, Ma X, Du Z, Li J, Duan Y, Du G
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways.
Jing H, Sun W, Fan J, Zhang Y, Yang J, Jia J, Li J, Guo J, Luo S, Zheng Y
Molecular medicine reports 2016 Apr;13(4):3009-16
Molecular medicine reports 2016 Apr;13(4):3009-16
RNA interference of Biot2 induces G1 phase arrest and apoptosis in mouse colorectal cancer cell line.
Zhou C, Zhang P, Xu GC, Wu DM, Liu RY, Zeng Q, Wang CT
Oncology research 2015;22(2):93-103
Oncology research 2015;22(2):93-103
Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway.
Zhang C, Zhang J, Li X, Sun N, Yu R, Zhao B, Yu D, Cheng Y, Liu Y
Evidence-based complementary and alternative medicine : eCAM 2015;2015:171356
Evidence-based complementary and alternative medicine : eCAM 2015;2015:171356
Pemetrexed induces G1 phase arrest and apoptosis through inhibiting Akt activation in human non small lung cancer cell line A549.
Wu DM, Zhang P, Xu GC, Tong AP, Zhou C, Lang JY, Wang CT
Asian Pacific journal of cancer prevention : APJCP 2015;16(4):1507-13
Asian Pacific journal of cancer prevention : APJCP 2015;16(4):1507-13
Lentivirus-mediated gene silencing of NOB1 suppresses non-small cell lung cancer cell proliferation.
Huang W, Zhong W, Xu J, Su B, Huang G, Du J, Liu Q
Oncology reports 2015 Sep;34(3):1510-6
Oncology reports 2015 Sep;34(3):1510-6
Doxorubicin-poly (ethylene glycol)-alendronate self-assembled micelles for targeted therapy of bone metastatic cancer.
Ye WL, Zhao YP, Li HQ, Na R, Li F, Mei QB, Zhao MG, Zhou SY
Scientific reports 2015 Sep 30;5:14614
Scientific reports 2015 Sep 30;5:14614
Low SFRP1 Expression Correlates with Poor Prognosis and Promotes Cell Invasion by Activating the Wnt/β-Catenin Signaling Pathway in NPC.
Ren XY, Zhou GQ, Jiang W, Sun Y, Xu YF, Li YQ, Tang XR, Wen X, He QM, Yang XJ, Liu N, Ma J
Cancer prevention research (Philadelphia, Pa.) 2015 Oct;8(10):968-77
Cancer prevention research (Philadelphia, Pa.) 2015 Oct;8(10):968-77
miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells.
He K, Tong D, Zhang S, Cai D, Wang L, Yang Y, Gao L, Chang S, Guo B, Song T, Li A, Huang C
International journal of oncology 2015 Oct;47(4):1528-36
International journal of oncology 2015 Oct;47(4):1528-36
Quercetin reverses experimental pulmonary arterial hypertension by modulating the TrkA pathway.
He Y, Cao X, Liu X, Li X, Xu Y, Liu J, Shi J
Experimental cell research 2015 Nov 15;339(1):122-34
Experimental cell research 2015 Nov 15;339(1):122-34
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Zhang Y, Zhang X, Huang J, Dong Q
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
Dai B, Wang W, Liu R, Wang H, Zhang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:227-33
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:227-33
MicroRNA-490-3P targets CDK1 and inhibits ovarian epithelial carcinoma tumorigenesis and progression.
Chen S, Chen X, Xiu YL, Sun KX, Zhao Y
Cancer letters 2015 Jun 28;362(1):122-30
Cancer letters 2015 Jun 28;362(1):122-30
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Xiao W, Jiang Y, Men Q, Yuan L, Huang Z, Liu T, Li W, Liu X
International journal of oncology 2015 Jan;46(1):360-8
International journal of oncology 2015 Jan;46(1):360-8
Knockdown of ANLN by lentivirus inhibits cell growth and migration in human breast cancer.
Zhou W, Wang Z, Shen N, Pi W, Jiang W, Huang J, Hu Y, Li X, Sun L
Molecular and cellular biochemistry 2015 Jan;398(1-2):11-9
Molecular and cellular biochemistry 2015 Jan;398(1-2):11-9
Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins.
Li X, Liu X, Xu Y, He Y, Liu J, Xie M
International journal of oncology 2015 Feb;46(2):677-84
International journal of oncology 2015 Feb;46(2):677-84
Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.
Chen X, Meng Q, Wang C, Liu Q, Sun H, Huo X, Sun P, Yang X, Peng J, Liu K
Pharmaceutical research 2015 Feb;32(2):538-48
Pharmaceutical research 2015 Feb;32(2):538-48
Capsaicin causes inactivation and degradation of the androgen receptor by inducing the restoration of miR-449a in prostate cancer.
Zheng L, Chen J, Ma Z, Liu W, Yang F, Yang Z, Wang K, Wang X, He D, Li L
Oncology reports 2015 Aug;34(2):1027-34
Oncology reports 2015 Aug;34(2):1027-34
STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer.
Xu Y, Zhang S, Niu H, Ye Y, Hu F, Chen S, Li X, Luo X, Jiang S, Liu Y, Chen Y, Li J, Xiang R, Li N
Scientific reports 2015 Aug 10;5:11754
Scientific reports 2015 Aug 10;5:11754
Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation.
Shan X, Fu YS, Aziz F, Wang XQ, Yan Q, Liu JW
PloS one 2014;9(12):e115401
PloS one 2014;9(12):e115401
Gemcitabine resistance in breast cancer cells regulated by PI3K/AKT-mediated cellular proliferation exerts negative feedback via the MEK/MAPK and mTOR pathways.
Yang XL, Lin FJ, Guo YJ, Shao ZM, Ou ZL
OncoTargets and therapy 2014;7:1033-42
OncoTargets and therapy 2014;7:1033-42
USP22 promotes the G1/S phase transition by upregulating FoxM1 expression via β-catenin nuclear localization and is associated with poor prognosis in stage II pancreatic ductal adenocarcinoma.
Ning Z, Wang A, Liang J, Xie Y, Liu J, Feng L, Yan Q, Wang Z
International journal of oncology 2014 Oct;45(4):1594-608
International journal of oncology 2014 Oct;45(4):1594-608
Knockdown of ZFX suppresses renal carcinoma cell growth and induces apoptosis.
Fang Q, Fu WH, Yang J, Li X, Zhou ZS, Chen ZW, Pan JH
Cancer genetics 2014 Oct-Dec;207(10-12):461-6
Cancer genetics 2014 Oct-Dec;207(10-12):461-6
Eupolyphaga sinensis Walker inhibits human chronic myeloid leukemia cell K562 growth by inducing G2-M phase cell cycle arrest and targeting EGFR signaling pathway and in S180 tumor-bearing mice.
Dai B, Zhan Y, Qi J, Zhang Y
Environmental toxicology and pharmacology 2014 May;37(3):1177-85
Environmental toxicology and pharmacology 2014 May;37(3):1177-85
Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells.
Duan F, Lin M, Li C, Ding X, Qian G, Zhang H, Ge S, Fan X, Li J
Cancer biology & therapy 2014 May;15(5):544-59
Cancer biology & therapy 2014 May;15(5):544-59
SOX2 regulates apoptosis through MAP4K4-survivin signaling pathway in human lung cancer cells.
Chen S, Li X, Lu D, Xu Y, Mou W, Wang L, Chen Y, Liu Y, Li X, Li LY, Liu L, Stupack D, Reisfeld RA, Xiang R, Li N
Carcinogenesis 2014 Mar;35(3):613-23
Carcinogenesis 2014 Mar;35(3):613-23
Downregulated protein O-fucosyl transferase 1 (Pofut1) expression exerts antiproliferative and antiadhesive effects on hepatocytes by inhibiting Notch signalling.
Annani-Akollor ME, Wang S, Fan J, Liu L, Padhiar AA, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014 Jul;68(6):785-90
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014 Jul;68(6):785-90
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Zhang Y, Zhan Y, Zhang D, Dai B, Ma W, Qi J, Liu R, He L
Scientific reports 2014 Jul 1;4:5518
Scientific reports 2014 Jul 1;4:5518
Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
Sun Q, Wang R, Wang Y, Luo J, Wang P, Cheng B
Oncology reports 2014 Feb;31(2):933-9
Oncology reports 2014 Feb;31(2):933-9
Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma.
Zhu X, Xu JJ, Hu SS, Feng JG, Jiang LH, Hou XX, Cao J, Han J, Ling ZQ, Ge MH
Journal of experimental & clinical cancer research : CR 2014 Dec 31;33(1):114
Journal of experimental & clinical cancer research : CR 2014 Dec 31;33(1):114
MiR-612 suppresses the stemness of liver cancer via Wnt/β-catenin signaling.
Tang J, Tao ZH, Wen D, Wan JL, Liu DL, Zhang S, Cui JF, Sun HC, Wang L, Zhou J, Fan J, Wu WZ
Biochemical and biophysical research communications 2014 Apr 25;447(1):210-5
Biochemical and biophysical research communications 2014 Apr 25;447(1):210-5
Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom.
Song Y, Gong K, Yan H, Hong W, Wang L, Wu Y, Li W, Li W, Cao Z
The Journal of biological chemistry 2014 Apr 25;289(17):11667-11680
The Journal of biological chemistry 2014 Apr 25;289(17):11667-11680
Hepatitis B viral RNA directly mediates down-regulation of the tumor suppressor microRNA miR-15a/miR-16-1 in hepatocytes.
Wang Y, Jiang L, Ji X, Yang B, Zhang Y, Fu XD
The Journal of biological chemistry 2013 Jun 21;288(25):18484-93
The Journal of biological chemistry 2013 Jun 21;288(25):18484-93
C1orf61 acts as a tumor activator in human hepatocellular carcinoma and is associated with tumorigenesis and metastasis.
Hu HM, Chen Y, Liu L, Zhang CG, Wang W, Gong K, Huang Z, Guo MX, Li WX, Li W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Jan;27(1):163-73
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Jan;27(1):163-73
Brucine, an effective natural compound derived from nux-vomica, induces G1 phase arrest and apoptosis in LoVo cells.
Zheng L, Wang X, Luo W, Zhan Y, Zhang Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Aug;58:332-9
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Aug;58:332-9
Caveolin-1 knockdown is associated with the metastasis and proliferation of human lung cancer cell line NCI-H460.
Song Y, Xue L, Du S, Sun M, Hu J, Hao L, Gong L, Yeh D, Xiong H, Shao S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2012 Sep;66(6):439-47
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2012 Sep;66(6):439-47
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 60186-1-Ig(CCND1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using CCND1 antibody 60186-1-lg at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red).
- Sample type
- cell line
