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- References [942]
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- Product number
- 60186-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60186-1-Ig, RRID:AB_10793718
- Product name
- Cyclin D1 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Cyclin D1 antibody (Cat. #60186-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2G3G5
- Vial size
- 20ul, 150ul
Submitted references SNX1 inhibits human ovarian cancer progression via regulation of the cell cycle, apoptosis and migration.
Pressurized intraperitoneal cold atmospheric plasma as a novel therapeutic strategy for peritoneal metastatic carcinoma.
Kaempferol stimulates dermal papilla cells and upregulates Wnt/β-catenin signaling pathway for androgenetic alopecia treatment.
Gallium-Doped MXene Nanozymes Protect Liver Through Multi-Death Pathway Blockade and Hepatocyte Regeneration.
Cold Exposure Alleviates Colitis via Parallel Integration of Colonic Mucosal Regeneration and Ileal Antimicrobial Defense.
FFAR4 negatively regulates colorectal cancer growth via blocking oxidative phosphorylation.
Downregulation of B7-H4 contributes to the synergistic effect of USP2a-targeted/anti-PD-1 combination therapy in EGFR mutant lung cancer.
The APC/C subunit APC7 promotes hepatocellular carcinoma progression by mediating ubiquitination and degradation of LATS1 to activate YAP/TAZ.
B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression.
Silencing of MAT2A inhibits gastric cancer cell proliferation, migration, and invasion through activation of the p53 pathway.
MEHP promotes breast cancer progression via GPR30-mediated epithelial-mesenchymal transition.
Transcriptomic analysis identifies CXCL12 as a novel candidate gene for litter size in rabbits.
SPON2 acts as a tumor promoter in HR-positive/HER2-negative breast cancer by regulating β-catenin signaling.
Anti-tumor effect of flavonoids isolated from Bidens Pilosa L. by regulating the activity of myeloid-derived suppressor cells within the tumor microenvironment in mice.
Prognostic value of BTG1 for predicting decitabine sensitivity in de novo acute myeloid leukemia.
MCM8 promotes colorectal cancer progression by competitively inhibiting HRD1-mediated CDC42 ubiquitination and degradation.
Upregulated ARMCX1 suppresses nasopharyngeal carcinoma progression by promoting TRIM21-mediated β-catenin degradation.
Mechanism of Babao Dan on fluorouracil-induced bone marrow suppression and T cell immune disorder through MAPK pathway.
FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo.
Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells.
Hexavalent chromium induced autophagy-dependent mTOR expression mediated by upregulation of HMGA2.
Exploring the potential mechanisms of PFAS exposure on colorectal cancer via combined bioinformatics analyses and experiments.
A novel PVA/QCS/AgNP hydrogel with antibacterial and healing-promoting efficacy for preventing postoperative pancreatic fistula in rats.
Macrophage USP14 suppresses Wnt/β-catenin signaling via NLK deubiquitination to enhance immune response.
Liver-muscle metabolic crosstalk: xanthosine as a key effector of broiler myogenesis.
A human patient-derived organoid biobank to model tumor heterogeneity and therapeutic vulnerability for oral squamous cell carcinoma.
Structural characterization and anti-hepatic fibrosis effects of a novel polysaccharide from Astragalus complanatus seeds.
RARG promotes gastric cancer progression by activating PMEPA1 transcription and Wnt/β-catenin signalling.
TMEM44 as a Novel Prognostic Marker for Hepatocellular Carcinoma is Associated with Tumor Invasion, Migration, and Apoptosis.
The multilayer coatings on polylactic acid implants spatiotemporally regulates the microenvironment to enhance antibacterial and osseointegration capacity.
Nuclear Pirin promotes HCC by acting as a key inflammation-facilitating factor.
Sodium-glucose cotransporter 2 inhibitor ameliorates podocyte hypertrophic stress by suppressing the mTOR/p70S6K/cyclin D1 signaling pathway in obesity-related nephropathy.
Neddylation of STAT3 is a potential therapeutic target for MASLD.
Phenethyl Isothiocyanate Suppresses Hepatocellular Carcinoma Progression and Immune Evasion via ZNF652 Regulation of PD-L1.
CYMP-AS1 Promotes Ovarian Cancer Progression by Enhancing the Intracellular Translocation of hnRNPM and Reducing the Stability of AXIN2 mRNA.
Terpinen-4-ol suppresses proliferation and motility of cutaneous squamous cell carcinoma cells by enhancing calpain-2 expression.
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
Multiaction Antimicrobial, Anti-inflammatory, and Prohealing Hydrogel as a Novel Strategy for Preventing Postoperative Pancreatic Fistula.
Tobacco carcinogen NNK promotes pancreatic cancer proliferation via LINC00857/β-catenin.
DNMT3a promotes LUAD cell proliferation and metastasis by activating the HDAC7 signalling pathway.
Mechanism of Curcumin in Inhibiting Proliferation of Head and Neck Squamous Cell Carcinoma: A Network Pharmacology and Cellular Experimental Study.
Inhibition of PHB1/PHB2 suppresses atherosclerotic plaque formation by interrupting PI3K/AKT/mTOR signaling.
FAM50A as a novel prognostic marker modulates the proliferation of colorectal cancer cells via CylinA2/CDK2 pathway.
STAG2 mutations in the normal colon induce upregulation of oncogenic pathways in neighbouring wildtype cells.
DDIAS promotes endometrial cancer progression via β-catenin signaling.
Hepatic Stellate Cell TM4SF1 Accelerates Hepatic Fibrosis Progression via Interacting With the Tyrosine Kinase c-Src.
Leonurine Attenuates CCl(4)-Induced Hepatic Fibrosis in Mice via the Hippo-YAP Pathway.
Bavachin suppresses proliferation of laryngopharyngeal cancer by regulating the STAT3 and MAPK signaling pathways.
EIF4A3 Promotes Cell Proliferation via CDC5L Upregulation in Human Breast Cancer Cells.
Capsaicin, the Pungent Component of Red Chili Pepper, induces p21-mediated Cell Cycle Arrest in Renal Cell Carcinoma via Downregulating GLI1: an Experimental Research In Vitro.
CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation.
Identification of an Ara-C resistance-related gene risk score and the role of S100A4 in AML via NR6A1-dependent activation and p53 regulation.
Dissecting the multi-omics landscape of TEAD1 in hepatocellular carcinoma: cycle regulation and metastatic potential.
Stimulation of regulatory dendritic cells suppresses cytotoxic T cell function and alleviates DEN-induced liver injury, fibrosis and hepatocellular carcinoma.
Inhibition of colorectal cancer cell growth by downregulation of M2-PK and reduction of aerobic glycolysis by clove active ingredients.
The type I ribosome-inactivating protein α-MMC induced significant apoptosis of lung cancer A549 and 95-D cells by activating the caspase cascade through TNF signaling pathway.
The regulatory role of the circELMOD3-associated ceRNA network in the progression and prognosis of hepatocellular carcinoma.
Developing a prognostic stratification model based on glutathione metabolism in thyroid cancer and validating RRM2's tumor-promoting role.
RBP7 knockdown inhibits proliferation of human hepatocellular carcinoma and activates the p38 MAPK pathway.
MiR-145-5p arrests the cell cycle by modulating SMAD5/cyclin D1 to inhibit gastric cancer progression.
Ginsenoside Rg5 enhances Abemaciclib sensitivity in ER+ breast cancer by modulating cell cycle proteins via transcriptional and post-translational levels.
METTL3 Mediates Wnt/β-Catenin Pathway in Epithelial-Mesenchymal Transition of 16HBE Cells Induced by Beryllium Sulphate.
SIX1 transmits signals for breast cancer progression via the ZEB1/IL6/STAT3 signaling axis.
KDM4C regulates trophoblast proliferation and migration in preeclampsia via the NFATc4/Wnt pathway.
SARS-CoV-2 nucleocapsid protein delays cell cycle in S-phase.
The chromatin remodeling factor BAP18 promotes non-small cell lung cancer progression via the recruitment of β-catenin with the transcriptional coactivator complex ACTL6A-PAF1.
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
TSZAF monomer combination downregulates the Wnt/β-catenin signaling pathway and inhibits neutrophil recruitment to prevent lung cancer metastasis.
Magnolin Promotes PINK1-Parkin-mediated Mitophagy in Diffuse Large B-cell Lymphoma Cells via PPAR-γ Pathway.
H3K36me3-Guided m(6)A Modification of Oncogenic L1CAM-AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma.
Inhibition of ICAM1 diminishes stemness and enhances antitumor immunity in glioblastoma via β-catenin/PD-L1 signaling.
MSCs-EXOs containing miR-21a-5p promoted cell proliferation in the rat retinal Müller cell rMC-1 via targeting LATS1.
Pracinostat inhibits the nefarious biological behavior of pancreatic cancer by targeting the miR-381-3p/MDM2 axis to activate the p53 signaling pathway.
Effect of rumen-protected guanidinoacetic acid provision as a dietary supplement on the growth, slaughter performance, and meat quality in simmental bulls.
Prrx1 promotes mesangial cell proliferation and kidney fibrosis through YAP in diabetic nephropathy.
METTL3-mediated modification of SIRT1 m6A methylation protects osteoblasts from TBHP-induced senescence and promotes osteoblast proliferation.
Comprehensive evaluation of the PCDHB family in gastric cancer: Prognostic significance, immune infiltration, and experimental validation of PCDHB5's oncogenic role.
BATF2-mediated control of astrocyte proliferation.
Integrating network pharmacology and pharmacological evaluation for investigating the active ingredient of Chinese herbal formula Zhuhuang Granule in psoriasis.
Dendrobin A inhibits gastric cancer: Mechanistic insights supported by integrated evidence.
DDX1 facilitates lenvatinib resistance in hepatocellular carcinoma through regulating ephrin-A3 and activating the Wnt/β-catenin signaling pathway.
Uridine-cytidine kinase 2 as a novel potential prognostic and therapeutic biomarker in gastric cancer.
Sorting nexin 9 expression and prognostic implications in lung adenocarcinoma: integrative bioinformatic and in vitro validation.
RTA-408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma.
Histone demethylase KDM9 activates the CCND1/AKT pathway to promote the malignant progression of gliomas through interaction with BRD2.
An integrated study on the role and underlying mechanism of QingFei Oral solution in pulmonary hypertension.
ZNF526 drives tumor growth by enhancing SHMT1-dependent serine metabolism and antioxidant capability in TNBC.
CDC26 facilitates ferroptosis through SLC7A11 degradation and cell cycle arrest.
Distinct functional heterogeneity of TP53 R175 mutations in platinum-resistant ovarian cancer: unveiling molecular mechanisms and therapeutic targets.
Knockdown of SUCLG2 inhibits glioblastoma proliferation and promotes apoptosis through LMNA acetylation and the mediation of H4K16la lactylation.
Genome-wide mapping of EBV-induced genomic variations identifies the role of MUC19 in EBV latency.
Exploring the mechanism of baicalein on breast cancer based on network pharmacology, molecular docking and in vivo experiments.
Deletion of smooth muscle ZFP36 promotes neointimal hyperplasia in mice.
COL1A1 promotes cell proliferation, cell cycle progression, and anoikis resistance in granulosa cells of chicken pre-ovulatory follicles.
HKDC1 promotes colorectal cancer progression by regulating RCOR1 expression to activate the Wnt/β-catenin pathway, enhancing proliferation, migration, and epithelial-mesenchymal transition.
The Role of PAX7 in Breast Cancer Prognosis and Its Mechanistic Involvement in the Wnt/β-Catenin Pathway.
AMPKα alleviates the inhibitory effect of NEFA on the function of bovine follicular granulosa cells cultured in vitro.
Integrated multi-omics characterization of neuroblastoma with bone or bone marrow metastasis.
Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low-Temperature Photothermal Therapy via Targeting HSP90-TXNDC9 Interactions.
Transglutaminase 2 nuclear localization enhances glioblastoma radiation resistance.
Mechanosensitive Piezo1 channel is highly expressed in the age-induced fibrotic uterus.
Targeting of the IL-33/Wnt axis restricts breast cancer stemness and metastasis.
MiR-485-3p/MELK cascade mediates tumor progression in pancreatic cancer.
Study on the molecular mechanism of UBA52 and BARD1 regulating hepatocellular carcinoma through the PI3 K/AKT signaling pathway.
Anlotinib enhances the efficacy of KRAS-G12C inhibitors through c-Myc/ORC2 axis inhibition in non-small cell lung cancer.
Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Expression and Promotes Cell Proliferation through Reduction of Apoptosis.
YTHDF1-targeting nanoassembly reverses tumoral immune evasion through epigenetics and cell cycle modulation.
SNORD9 promotes ovarian cancer tumorigenesis via METTL3/IGF2BP2-mediated NFYA m6A modification and is a potential target for antisense oligonucleotide therapy.
Penta-1,4-dien-3-one and quinoxaline conjugates as potential anticancer agents via inhibiting EphB3/SRC/AKT axis.
Liraglutide improves senescence and ameliorating diabetic sarcopenia via the YAP-TAZ pathway.
The MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.
HOGA1 Suppresses Renal Cell Carcinoma Growth via Inhibiting the Wnt/β-Catenin Signalling Pathway.
GAS41 promotes ITGA4-mediated PI3K/Akt/mTOR signaling pathway and glioma tumorigenesis.
SEPT5 overexpression predicts poor prognosis and promotes progression through feedback regulation of HIF-1α in clear cell renal cell carcinoma.
CTSG restraines the proliferation and metastasis of head and neck squamous cell carcinoma by blocking the JAK2/STAT3 pathway.
The LncRNA lnc-POTEM-4:14 promotes HCC progression by interacting with FOXK1.
Enhancing KRAS G12D inhibitor sensitivity in pancreatic cancer through SHP2/PI3K pathway.
c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy.
TMEM176B inhibits ovarian cancer progression by regulating EMT via the Wnt/β-catenin signaling pathway.
HSPD1-facilitated formation of CTPS cytoophidia promotes proliferation in C2C12 cells.
Tasquinimod promotes the sensitivity of ovarian cancer cells to cisplatin by down-regulating the HDAC4/p21 pathway.
Targeting DUSP3 promotes cell senescence by activating the notch1 pathway to treat hepatocellular carcinoma.
Rictor orchestrates β-catenin/FOXO balance by maintaining redox homeostasis during development of ovarian cancer.
A novel piperine derivative HJ-23 exhibits anti-colorectal cancer effects by activating the p53 pathway.
Impacts of dietary arginine supplementation on performance, nutrient digestion and expression of proteins related to milk fatty acid and casein synthesis in early lactating dairy cows.
Targeting the MDK/c-Myc complex to overcome temozolomide resistance in glioma.
Effect of COL11A1 on oral squamous cell carcinoma.
MAT2A Knockdown Enhances Recombinant Protein Expression in Transgenic CHO Cells Through Regulation of Cell Cycle.
Suppression of MRPL23 induces cellular senescence in hepatocellular carcinoma by targeting HMGB1.
Apigenin prevents hypertensive vascular remodeling by regulating the TP53 pathway.
Serine/threonine/tyrosine kinase 1 drives pancreatic carcinogenesis via GSK3β sequestration-mediated Wnt/β-catenin pathway hyperactivation.
FSTL3 promotes colorectal cancer by activating the HIF1 pathway.
Study on the role of miR-10b-3p as SASP in exosomes of premature senescent hepatocytes induced by hexavalent chromium.
Genome-guided discovery of coublibactins from Nocardia coubleae and their gallium complexes with potent antileukemic activity.
HNF4A promotes tumor progression in gastric cancer by transcriptional activation of KIF2C.
Glycyrrhizic acid promotes liver regeneration through activating β-catenin in acetaminophen-induced liver injury.
Modulation of copper homeostasis and cuproptosis by PDHA1 in acute myeloid leukemia.
Role of thrombus-derived exosomal lncRNA LOC101928697 in regulating endothelial function via FUS protein interaction in myocardial infarction.
Annexin A2: regulating glioma's fate and a potential therapeutic target.
High glucose inhibits proliferation, migration, and osteogenic differentiation of human placenta-derived mesenchymal stem cells.
Elevated SGO2 expression in lung adenocarcinoma promotes migration and invasion via MAD2 and correlates with poor prognosis.
Keratin 6A Overexpression in the Lymphovascular Invasion-Associated Tumor Subgroup Promotes Progression of Triple-Negative Breast Cancer.
CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism.
CircSMAD3 represses VSMC phenotype switching and neointima formation via promoting hnRNPA1 ubiquitination degradation.
Smurf2 Suppresses Proliferation and Cell Cycle of Triple-Negative Breast Cancer Cells by Promoting the Polyubiquitination and Degradation of RPL35A.
IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth.
Delactylation diminished the growth inhibitory role of CA3 by restoring DUOX2 expression in hepatocellular carcinoma.
Environmental high temperature (heat stroke) causes articular cartilage damage in vivo and in vitro.
Elevated SREBP1 accelerates the initiation and growth of pancreatic cancer by targeting SOX9.
miR-28-3p suppresses gastric cancer growth and EMT-driven metastasis by targeting the ARF6/Hedgehog axis.
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis.
Organophosphate flame retardant triphenyl phosphate (TPhP) induced colonic fibrosis by bringing about epithelial-mesenchymal transition.
Environmental high temperature induced cartilage damage through triggering programmed necrosis mediated by producing left-handed DNA.
Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway.
PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53.
Endothelial AGGF1 promotes retinal angiogenesis by coordinating TNFSF12/FN14 signalling.
Low expression of PRTN3 regulates the progression of gastric cancer by inhibition of cell cycle and promotion of apoptosis.
Thermoradiotherapy reverses proliferation, metastasis, and anoikis resistance in glioblastoma through ITGA5-PI3K/AKT axis.
WGCNA-identified COL13A1 drives osteosarcoma metastasis and progression via TGF-β signaling.
Bavachinin exerts anti-tumor effects by activating TLR4/STING axis-dependent PANoptosis and synergistically enhances chemosensitivity in endometrial cancer.
Targeting TRAF6 inhibits cystogenesis in autosomal dominant polycystic kidney disease.
Influence of coated cobalamin on lactation performance, nutrient digestion, and proteins related to mammary epithelial cell proliferation and milk fatty acid synthesis in dairy cows.
Evaluation of anti-tumor activity of borated camptothecin derivatives targeting topoisomerase 1 against hepatocellular carcinoma and intrahepatic cholangiocarcinoma.
Elevated SNHG15 empowers keratinocytes hyperproliferation through activation of STAT3/Cyclin D1 axis in psoriasis.
Albiflorin enhances the antitumor effects of propofol in hepatocellular carcinoma cells by inhibiting the Wnt/β-catenin signaling activation.
TRIM47-facilitated PLK1 stabilization promotes the proliferation of liver cancer cells.
Depleting CBR1 increases chemosensitivity by reducing stemness and quiescence traits in non-small cell lung cancer.
Integrated multi-omics analysis revealed that SMARCAL1 serves as an immune related prognostic marker and promotes liver cancer growth via the Hippo/YAP signaling axis.
THOC1 binds to U2AF2 and regulates ovarian cancer progression through the beta-catenin / c-myc / cyclinD1 signaling pathway.
ZEB1 Contributes to Drug Resistance Through Canonical Wnt Signaling in Lung Cancer.
Application of PVA hydrogel loaded with luteolin nanoparticles in anti EMT treatment after GBM.
Decellularized human amniotic member hydrogel promotes limbal stem cells proliferation.
LIMK1 as a Novel Kinase of β-Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5.
Folic acid-functionalized PLGA nanomedicines encapsulating echinacoside for liver cancer therapy.
WEE1 inhibitor exerts synergistic effect with KRAS G12C inhibitor via MYBL2-RRM2 axis in KRAS(G12C)-mutant lung cancer.
Paris saponin VII restrains PD-L1 mediated immune evasion through the AKT1 and STAT3 signaling pathways.
RNA-binding motif protein RBM39 enhances the proliferation of gastric cancer cells by facilitating an oncogenic splicing switch in MRPL33.
ELK4 induced upregulation of HOMER3 promotes the proliferation and metastasis in glioma via Wnt/β-catenin/EMT signaling pathway.
KIF14 plays a role in the regulation of the cell cycle and has implications for prognosis in clear cell renal cell carcinoma.
A comprehensive analysis of deubiquitinase USP20 on prognosis and immunity in pan-cancer.
Comprehensive analysis illustrating the role of HOXB8 in head and neck squamous cell carcinoma: evidence from multi-omics analysis and experiments validation.
F-box protein FBXO32 ubiquitinates and stabilizes D-type cyclins to drive cancer progression.
SAP30 promotes clear cell renal cell carcinoma proliferation and inhibits apoptosis through the MT1G axis.
CYR61 Acts as an Intracellular Microtubule-Associated Protein and Coordinates Mitotic Progression via PLK1-FBW7 Pathway.
Cross-border regulation of the STK39/MAPK14 pathway by Lycium barbarum miR166a to inhibit triple-negative breast cancer.
CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis.
Apolipoprotein L3 inhibits breast cancer proliferation and modulates cell cycle via the P53 pathway.
GRB7-mediated enhancement of cell malignant characteristics induced by Helicobacter pylori infection.
YTHDC1 Regulates the Migration, Invasion, Proliferation, and Apoptosis of Rheumatoid Fibroblast-Like Synoviocytes.
High glucose-induced NCAPD2 upregulation promotes malignant phenotypes and regulates EMT via the Wnt/β-catenin signaling pathway in HCC.
Brucine Suppresses Malignant Progression of Prostate Cancer by Decreasing Sarcosine Accumulation via Downregulation of GNMT in the Glycine/sarcosine Metabolic Pathway.
Mechanistic elucidation of QiJu-DiHuang Wan in management of age-related dry eye through metabolomics and network pharmacology.
Integrative analysis of the transcriptome and metabolome reveals the importance of hepatokine FGF21 in liver aging.
DCAF7 Acts as A Scaffold to Recruit USP10 for G3BP1 Deubiquitylation and Facilitates Chemoresistance and Metastasis in Nasopharyngeal Carcinoma.
Tudor-SN exacerbates pathological vascular remodeling by promoting the polyubiquitination of PTEN via NEDD4-1.
KIFC3 promotes the proliferation, migration and invasion of non-small cell lung cancer through the PI3K/AKT signaling pathway.
ARMCX1 inhibits lung adenocarcinoma progression by recruiting FBXW7 for c-Myc degradation.
Avermectin B1 mediates antitumor activity and induces autophagy in osteosarcoma through the AMPK/ULK1 signaling pathway.
Xylooligosaccharides alleviate the carbohydrate-enriched diet-induced intestinal barrier dysfunction in carp Megalobrama amblycephala by promoting intestinal development, immunity and gut microbiota.
Investigation on the mechanism of androsta-4,6,8,14-tetraene-3,11,16-trione against acute lymphoblastic leukemia.
Identification and biological evaluation of fused tetrahydroisoquinoline derivatives as Wnt/β-catenin signaling inhibitors to suppress colorectal cancer.
Elevated RBP4 in Subclinical Ketosis Cows Inhibits Follicular Granulosa Cell Proliferation and Steroid Hormone Synthesis.
Glycyrrhizin ameliorates colorectal cancer progression by regulating NHEJ pathway through inhibiting HMGB1-induced DNA damage response.
Discovery of Potent Covalent CRM1 Inhibitors Via a Customized Structure-Based Virtual Screening Pipeline and Bioassays.
FAM83D promotes the progression of 4NQO-induced esophageal carcinoma via inhibiting FBWX7.
NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.
DEAD/H-box helicase 11 is transcriptionally activated by Yin Yang-1 and accelerates oral squamous cell carcinoma progression.
CircZMYM2 plays a pivotal role in osteosarcoma by regulating the translation of NACA and ARPC1B.
Inhibition of the E3 ligase UBR5 stabilizes TERT and protects vascular organoids from oxidative stress.
Enhancing radiosensitivity in osteosarcoma via CDKN2C overexpression: A mechanism involving G1 phase arrest mediated by inhibition of CDK4 expression and Thr172 phosphorylation.
P4HB maintains Wnt-dependent stemness in glioblastoma stem cells as a precision therapeutic target and serum marker.
GOS enhances BDNF-mediated mammary gland development in pubertal mice via the gut-brain axis.
Hypoxia Stimulates PYGB Enzymatic Activity to Promote Glycogen Metabolism and Cholangiocarcinoma Progression.
TBBPA exposure causes cartilage cell damage in both in vitro and in vivo models.
SPIN1 accelerates tumorigenesis and confers radioresistance in non-small cell lung cancer by orchestrating the FOXO3a/FOXM1 axis.
Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells.
Disulfiram Upgrades the Radiosensitivity of Osteosarcoma by Enhancing Apoptosis and P53-Induced Cell Cycle Arrest.
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
Integrating Epigenetics, Proteomics, and Metabolomics to Reveal the Involvement of Wnt/β-Catenin Signaling Pathway in Oridonin-Induced Reproductive Toxicity.
Circ_0001671 regulates prostate cancer progression through miR-27b-3p/BLM axis.
Antitumour effects of artesunate via cell cycle checkpoint controls in human oesophageal squamous carcinoma cells.
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.
IDH1 mutation produces R-2-hydroxyglutarate (R-2HG) and induces mir-182-5p expression to regulate cell cycle and tumor formation in glioma.
Curdepsidone A Induces Intrinsic Apoptosis and Inhibits Protective Autophagy via the ROS/PI3K/AKT Signaling Pathway in HeLa Cells.
Combined SET7/9 and CDK4 inhibition act synergistically against osteosarcoma.
Copper Chaperone Atox1 Protected the Cochlea From Cisplatin by Regulating the Copper Transport Family and Cell Cycle.
Cynaroside Induces G1 Cell Cycle Arrest by Downregulating Cell Division Cycle 25A in Colorectal Cancer.
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
ART1 knockdown decreases the IL-6-induced proliferation of colorectal cancer cells.
YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia.
CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8 + T cell response.
β-catenin/TCF4-induced SCUBE3 upregulation promotes ovarian cancer development via HIF-1 signaling pathway.
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
ZNF862 induces cytostasis and apoptosis via the p21-RB1 and Bcl-xL-Caspase 3 signaling pathways in human gingival fibroblasts.
Bioinspired engineering ADSC nanovesicles thermosensitive hydrogel enhance autophagy of dermal papilla cells for androgenetic alopecia treatment.
AS1411 binds to nucleolin via its parallel structure and disrupts the exos-miRNA-27a-mediated reciprocal activation loop between glioma and astrocytes.
Teriflunomide/leflunomide synergize with chemotherapeutics by decreasing mitochondrial fragmentation via DRP1 in SCLC.
Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinoma.
Potential Molecular Mechanism of Illicium simonsii Maxim Petroleum Ether Fraction in the Treatment of Hepatocellular Carcinoma.
Design, synthesis and biological evaluation of indoline-maleimide conjugates as potential antitumor agents for the treatment of colorectal cancer.
Naringenin enhances the efficacy of ferroptosis inducers by attenuating aerobic glycolysis by activating the AMPK-PGC1α signalling axis in liver cancer.
ANGPTL3 diminishes the resistance of ovarian cancer to paclitaxel by blocking the PI3K-AKT-mTOR signaling pathway.
Overexpression of FHL1 suppresses papillary thyroid cancer proliferation and progression via inhibiting Wnt/β-catenin pathway.
Melatonin promotes cell cycle progression of neural stem cells subjected to manganese via Nurr1.
Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells.
HNF4α improves hepatocyte regeneration by upregulating PXR.
SPP1 could be an immunological and prognostic biomarker: From pan-cancer comprehensive analysis to osteosarcoma validation.
Exploring the key genes associated with breast cancer radiotherapy sensitivity based on the stromal-immune score and analysis of the WGCNA and ceRNA network.
Screening and identification of miRNAs negatively regulating FAM83A/Wnt/β-catenin signaling pathway in non-small cell lung cancer.
Inhibition of DNA Topoisomerase Ι by Flavonoids and Polyacetylenes Isolated from Bidens pilosa L.
miR-126a-5p inhibits H1N1-induced inflammation and matrix protease secretion in lung fibroblasts by targeting ADAMTS-4.
let-7g sensitized liver cancer cells to 5-fluorouracil by downregulating ABCC10 expression.
MALAT1/miR-7-5p/TCF4 Axis Regulating Menstrual Blood Mesenchymal Stem Cells Improve Thin Endometrium Fertility by the Wnt Signaling Pathway.
TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma.
MiR-199a-5p inhibits dermal papilla cells proliferation by regulating VEGFA expression in cashmere goat.
CHEK2 knockout is a therapeutic target for TP53-mutated hepatocellular carcinoma.
Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Cepharanthine suppresses APC-mutant colorectal cancers by down-regulating the expression of β-catenin.
Schisandrin B promotes hepatic differentiation from human umbilical cord mesenchymal stem cells.
ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner.
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
Pharmacological USP2 targeting suppresses ovarian cancer growth by potentiating apoptosis and ferroptosis.
Knockdown of PIK3R6 impedes the onset and advancement of clear cell renal cell carcinoma.
BMP5 promotes trophoblast functions upon N-glycosylation via the BMP5-SMAD1/5 signaling pathway in preeclampsia.
MEK inhibitor trametinib combined with PI3K/mTOR inhibitor BEZ-235 as an effective strategy against NSCLC through impairment of glucose metabolism.
Pharmacological inhibition of SREBP1 suppresses pancreatic cancer growth via inducing GPX4-mediated ferroptosis.
miR-548az-5p induces amniotic epithelial cell senescence by regulating KATNAL1 expression in labor.
GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT3.
F13B regulates angiogenesis and tumor progression in hepatocellular carcinoma via the HIF-1α/VEGF pathway.
Cyclosporine A Causes Gingival Overgrowth by Promoting Entry into the S Phase at the G1/S Cell Cycle Checkpoint in Gingival Fibroblasts Exposed to Lipopolysaccharide.
Enhancing therapeutic efficacy in homologous recombination-proficient pancreatic cancer via the combination of PARP1-PROTAC and a BRD4 inhibitor.
Dendrobium nobile active ingredient Dendrobin A against hepatocellular carcinoma via inhibiting nuclear factor kappa-B signaling.
Antitumorigenic potential of Lactobacillus-derived extracellular vesicles: p53 succinylation and glycolytic reprogramming in intestinal epithelial cells via SIRT5 modulation.
Identification of TAT as a Biomarker Involved in Cell Cycle and DNA Repair in Breast Cancer.
MZT2A serves as a prognostic biomarker and promotes the progression of kidney renal clear cell carcinoma.
Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis.
Bufalin Suppresses Head and Neck Cancer Development by Modulating Immune Responses and Targeting the β-Catenin Signaling Pathway.
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Matairesinoside, a novel inhibitor of TMEM16A ion channel, loaded with functional hydrogel for lung cancer treatment.
TuBG1 promotes hepatocellular carcinoma via ATR/P53-apoptosis and cycling pathways.
Cadmium disrupts spermatogenic cell cycle via piRNA-DQ717867/p53 pathway.
Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
RETRACTED: High PGC-1α Expression as a Poor Prognostic Indicator in Intracranial Glioma.
Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer.
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
Peptide Inhibitor Targeting the Extraterminal Domain in BRD4 Potently Suppresses Breast Cancer Both In Vitro and In Vivo.
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression.
Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma.
PRMT6-mediated transcriptional activation of ythdf2 promotes glioblastoma migration, invasion, and emt via the wnt-β-catenin pathway.
The role of miR-222-2p in exosomes secreted by hexavalent chromium-induced premature senescent hepatocytes as a SASP component.
Isolation and Cultivation of Vascular Smooth Muscle Cells from the Mouse Circle of Willis.
MKRN1/2 serve as tumor suppressors in renal clear cell carcinoma by regulating the expression of p53.
NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner.
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
The cancer/testis antigen HORMAD1 promotes gastric cancer progression by activating the NF-κB signaling pathway and inducing epithelial-mesenchymal transition.
PRMT7 Inhibits the Proliferation and Migration of Gastric Cancer Cells by Suppressing the PI3K/AKT Pathway via PTEN.
HSP105 suppresses the progression of cutaneous squamous cell carcinoma by activating the P53 signaling pathway.
Prognostic and therapeutic implications of iron-related cell death pathways in acute myeloid leukemia.
Role of UDP-glucose ceramide glucosyltransferase in venous malformation.
LINC02870 facilitates SNAIL translation to promote hepatocellular carcinoma progression.
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression.
CCDC85C suppresses colorectal cancer cells proliferation and metastasis through activating GSK-3β and promoting β-catenin degradation.
SUMO-Activating Enzyme Subunit 1 Is Associated with Poor Prognosis, Tumor Progression, and Radio-Resistance in Colorectal Cancer.
Ar-turmerone inhibits the proliferation and mobility of glioma by downregulating cathepsin B.
Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.
DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
MTHFD2 promotes PD-L1 expression via activation of the JAK/STAT signalling pathway in bladder cancer.
Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.
Role of Nucleobindin-2 in the Clinical Pathogenesis and Treatment Resistance of Glioblastoma.
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
A pan-cancer analysis of the role of HOXD1, HOXD3, and HOXD4 and validation in renal cell carcinoma.
IGF2BP2 acts as a m(6)A modification regulator in laryngeal squamous cell carcinoma through facilitating CDK6 mRNA stabilization.
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice.
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
IL-7 promotes CD19-directed CAR-T cells proliferation through miRNA-98-5p by targeting CDKN1A.
A large-scale transcriptional analysis reveals herb-derived ginsenoside F2 suppressing hepatocellular carcinoma via inhibiting STAT3.
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
Tripartite motif 31 drives gastric cancer cell proliferation and invasion through activating the Wnt/β-catenin pathway by regulating Axin1 protein stability.
GAD1-mediated GABA elicits aggressive characteristics of human oral cancer cells.
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
Targeting diacylglycerol kinase α impairs lung tumorigenesis by inhibiting cyclin D3.
The High Level of RANKL Improves IκB/p65/Cyclin D1 Expression and Decreases p-Stat5 Expression in Firm Udder of Dairy Goats.
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Microtubule-associated protein 4 promotes epithelial mesenchymal transition in hepatocellular cancer cells via regulating GSK3β/β-catenin pathway.
Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity.
The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury.
Pan-cancer analysis of PCAT6 and its effect on oesophageal squamous cell carcinoma cell proliferation and migration.
Human umbilical cord mesenchymal stem cells conditioned medium exerts anti-tumor effects on KGN cells in a cell density-dependent manner through activation of the Hippo pathway.
Ursolic acid nanoparticles for glioblastoma therapy.
MicroRNA-137 inhibits pituitary prolactinoma proliferation by targeting AKT2.
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway.
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.
HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma.
eIF3a sustains non-small cell lung cancer stem cell-like properties by promoting YY1-mediated transcriptional activation of β-catenin.
Ethyl acetate extract of Antenoron Filiforme inhibits the proliferation of triple negative breast cancer cells via suppressing Skp2/p21 signaling axis.
Targeting CDK12 obviates the malignant phenotypes of colorectal cancer through the Wnt/β-catenin signaling pathway.
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
ZYY-B-2, a novel ALK inhibitor, overcomes resistance to ceritinib by inhibiting P-gp function and induces apoptosis through mitochondrial pathway in ceritinib-resistant H2228 cells.
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
Analysis of Promoter Methylation of the Bovine FOXO1 Gene and Its Effect on Proliferation and Differentiation of Myoblasts.
Triptonide inhibits growth and metastasis in HCC by suppressing EGFR/PI3K/AKT signaling.
Effects of the CDC10 (Septin 7) Gene on the Proliferation and Differentiation of Bovine Intramuscular Preadipocyte and 3T3-L1 Cells.
Krüppel-like Factor 7 inhibits proliferation and migration of pulmonary smooth muscle cells via p21 activation.
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening.
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1.
ANXA3, associated with YAP1 regulation, participates in the proliferation and chemoresistance of cervical cancer cells.
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
Effects of dietary folic acid supplementation on lactation performance and mammary epithelial cell development of dairy cows and its regulatory mechanism.
Exogenous H(2)S alleviates senescence of glomerular mesangial cells through up-regulating mitophagy by activation of AMPK-ULK1-PINK1-parkin pathway in mice.
NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis.
TC2N Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Targeting the Wnt/β-Catenin Signaling Pathway.
LINC00921 reduces lung cancer radiosensitivity by destabilizing NUDT21 and driving aberrant MED23 alternative polyadenylation.
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Aberrant epithelial cell interaction promotes esophageal squamous-cell carcinoma development and progression.
CD56 polysialylation promotes the tumorigenesis and progression via the Hedgehog and Wnt/β-catenin signaling pathways in clear cell renal cell carcinoma.
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer.
Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.
Lysine-Specific Demethylase 4D Is Critical for the Regulation of the Cell Cycle and Antioxidant Capacity in Goat Fibroblast Cells.
Histone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia.
High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.
Knockdown of KDM5B Leads to DNA Damage and Cell Cycle Arrest in Granulosa Cells via MTF1.
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer.
8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells.
Septin11 promotes hepatocellular carcinoma cell motility by activating RhoA to regulate cytoskeleton and cell adhesion.
Upregulation of TMEM40 is associated with the malignant behavior and promotes tumor progression in cervical cancer.
Structural Characterization and Anti-breast Cancer Activity in vitro of a Novel Polysaccharide From Cymbopogon citratus.
Intervention Mechanism of Hunag-Lian Jie-Du Decoction on Canonical Wnt/β-Catenin Signaling Pathway in Psoriasis Mouse Model.
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.
CCDC65, a Gene Knockout that leads to Early Death of Mice, acts as a potentially Novel Tumor Suppressor in Lung Adenocarcinoma.
CAMTA1 gene affects the ischemia-reperfusion injury by regulating CCND1.
Chrysin Ameliorates Influenza Virus Infection in the Upper Airways by Repressing Virus-Induced Cell Cycle Arrest and Mitochondria-Dependent Apoptosis.
METTL3/m(6)A/IFIT2 regulates proliferation, invasion and immunity in esophageal squamous cell carcinoma.
Targeting type Iγ phosphatidylinositol phosphate kinase overcomes oxaliplatin resistance in colorectal cancer.
E2F1-mediated GINS2 transcriptional activation promotes tumor progression through PI3K/AKT/mTOR pathway in hepatocellular carcinoma.
INPP4B inhibits glioma cell proliferation and immune escape via inhibition of the PI3K/AKT signaling pathway.
Synergistic effects of nab-PTX and anti-PD-1 antibody combination against lung cancer by regulating the Pi3K/AKT pathway through the Serpinc1 gene.
Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.
Increased Methyl-CpG-Binding Domain Protein 2 Promotes Cigarette Smoke-Induced Pulmonary Hypertension.
HRK inhibits colorectal cancer cells proliferation by suppressing the PI3K/AKT/mTOR pathway.
Identification and validation of a potential key gene SGOL1 for poor prognosis in hepatocellular carcinoma based on a bioinformatics approach.
A long noncoding RNA GTF2IRD2P1 suppresses cell proliferation in bladder cancer by inhibiting the Wnt/β‑catenin signaling pathway.
SERPINA5 promotes tumour cell proliferation by modulating the PI3K/AKT/mTOR signalling pathway in gastric cancer.
Combined treatment with dihydrotestosterone and lipopolysaccharide modulates prostate homeostasis by upregulating TNF-α from M1 macrophages and promotes proliferation of prostate stromal cells.
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation through the Chi-miR-214-3p/β-Catenin Axis in Cashmere Goats.
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE.
Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy.
CTPS cytoophidia formation affects cell cycle progression and promotes TSN‑induced apoptosis of MKN45 cells.
HCV Core protein represses DKK3 expression via epigenetic silencing and activates the Wnt/β-catenin signaling pathway during the progression of HCC.
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Transfer RNA-derived fragment 5'tRF-Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen-related cell adhesion molecule 1.
RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Hepatocyte-derived VEGFA accelerates the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via activating hepatic stellate cells.
Lysine stimulates the development of the murine mammary gland at puberty via PI3K/AKT/mTOR signalling axis.
Blockade of c-Met-Mediated Signaling Pathways by E7050 Suppresses Growth and Promotes Apoptosis in Multidrug-Resistant Human Uterine Sarcoma Cells.
Discovery of a Novel Bloom's Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer.
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
Potential mechanisms underlying the promoting effects of 3D collagen scaffold culture on stemness and drug resistance of glioma cells.
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Skimmianine as a novel therapeutic agent suppresses proliferation and migration of human esophageal squamous cell carcinoma via blocking the activation of ERK1/2.
The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway.
In vitro and in vivo anti-lymphoma effects of Ophiorrhiza pumila extract.
Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.
Arylquin 1 (Potent Par-4 Secretagogue) Inhibits Tumor Progression and Induces Apoptosis in Colon Cancer Cells.
Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway.
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
A novel mechanism of the lncRNA PTTG3P/miR-142-5p/JAG1 axis modulating tongue cancer cell phenotypes through the Notch1 signaling.
Cyclin D1 mediated by the nuclear translocation of nuclear factor kappa B exerts an oncogenic role in lung cancer.
Pseudophosphatase STYX is induced by Helicobacter pylori and promotes gastric cancer progression by inhibiting FBXO31 function.
Long noncoding RNA Gm31629 protects against mucosal damage in experimental colitis via YB-1/E2F pathway.
HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway.
Transcription Factor Specificity Protein 1 Regulates Inflammation and Fibrin Deposition in Nasal Polyps Via the Regulation of microRNA-125b and the Wnt/β-catenin Signaling Pathway.
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H(2)S in Diabetes.
Paired box 8 facilitates the c-MYC related cell cycle progress in TP53-mutation uterine corpus endometrial carcinoma through interaction with DDX5.
Near-Infrared Light-Responsive Nanoinhibitors for Tumor Suppression through Targeting and Regulating Anion Channels.
Caffeic Acid, an Active Ingredient in Coffee, Combines with DOX for Multitarget Combination Therapy of Lung Cancer.
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Knockdown of EphB3 inhibits cell proliferation partly through the AKT signaling pathway and represses epithelial-mesenchymal transition in esophageal squamous cell carcinoma.
Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies.
Betulinic acid self-assembled nanoparticles for effective treatment of glioblastoma.
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
PRUNE2 inhibits progression of colorectal cancer in vitro and in vivo.
The miR-34a/WNT7B modulates the sensitivity of cholangiocarcinoma cells to p53-mediated photodynamic therapy toxicity.
FERMT1 contributes to the migration and invasion of nasopharyngeal carcinoma through epithelial-mesenchymal transition and cell cycle arrest.
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Characterization and functional analysis of lncRNA2690 in regulating the growth cycle of the hair follicle in rabbits.
ALG8 Fuels Stemness Through Glycosylation of the WNT/Beta-Catenin Signaling Pathway in Colon Cancer.
PRRX1 promotes colorectal cancer stemness and chemoresistance via the JAK2/STAT3 axis by targeting IL-6.
miR-29b-3p inhibits 22Rv1 prostate cancer cell proliferation through the YWHAE/BCL-2 regulatory axis.
NSUN2-mediated RNA m(5)C modification modulates uveal melanoma cell proliferation and migration.
LAP3 contributes to IFN-γ-induced arginine depletion and malignant transformation of bovine mammary epithelial cells.
lncRNA2919 Suppresses Rabbit Dermal Papilla Cell Proliferation via trans-Regulatory Actions.
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c-Myc pathway in patients with estrogen receptor-positive breast cancer.
DNA Methylation Mediates lncRNA2919 Regulation of Hair Follicle Regeneration.
The effects of Jiawei Duhuo Jisheng mixture on Wnt/β-catenin signaling pathway in the synovium inflamed by knee osteoarthritis: An in vitro and in vivo experiment.
Dematin inhibits glioblastoma malignancy through RhoA-mediated CDKs downregulation and cytoskeleton remodeling.
Elevated FAM84B promotes cell proliferation via interacting with NPM1 in esophageal squamous cell carcinoma.
Bolbostemma paniculatum (Maxim.) Franquet extract suppresses the development of colorectal cancer through downregulation of PI3K/Akt pathway.
CYLD deficiency enhances metabolic reprogramming and tumor progression in nasopharyngeal carcinoma via PFKFB3.
β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway.
CDK5RAP3 acts as a putative tumor inhibitor in papillary thyroid carcinoma via modulation of Akt/GSK-3β/Wnt/β-catenin signaling.
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.
Effect of Photodynamic Therapy on Gemcitabine-Resistant Cholangiocarcinoma in vitro and in vivo Through KLF10 and EGFR.
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
NAP1L1 Functions as a Tumor Promoter via Recruiting Hepatoma-Derived Growth Factor/c-Jun Signal in Hepatocellular Carcinoma.
CORO6 Promotes Cell Growth and Invasion of Clear Cell Renal Cell Carcinoma via Activation of WNT Signaling.
LHPP-Mediated Histidine Dephosphorylation Suppresses the Self-Renewal of Mouse Embryonic Stem Cells.
17β-Estradiol Inhibits Proliferation and Oxidative Stress in Vascular Smooth Muscle Cells by Upregulating BHLHE40 Expression.
Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.
Transcription Factors BARX1 and DLX4 Contribute to Progression of Clear Cell Renal Cell Carcinoma via Promoting Proliferation and Epithelial-Mesenchymal Transition.
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma.
The Mechanism of miR-141 Regulating the Proliferation and Metastasis of Liver Cancer Cells by Targeting STAT4.
Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma.
Increased Collagen Type V α2 (COL5A2) in Colorectal Cancer is Associated with Poor Prognosis and Tumor Progression.
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
A novel function for cyclin D1 as a transcriptional role in oncogenesis and tumor development by ChIP-Seq and RNA-Seq.
Lenvatinib induces anticancer activity in gallbladder cancer by targeting AKT.
Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder Cancer.
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Therapeutic Potential of CUDC-907 (Fimepinostat) for Hepatocarcinoma Treatment Revealed by Tumor Spheroids-Based Drug Screening.
Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for Treatment of Lung Adenocarcinoma.
SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer.
tRNA-Derived Fragment tRF-Glu-TTC-027 Regulates the Progression of Gastric Carcinoma via MAPK Signaling Pathway.
The lncRNA CASC2 Modulates Hepatocellular Carcinoma Cell Sensitivity and Resistance to TRAIL Through Apoptotic and Non-Apoptotic Signaling.
Role of Notch pathway in effect of mono-2-ethylhexyl phthalate on the proliferation and cell cycle of SH-SY5Y cell.
TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma.
The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy.
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.
Bromodomain-containing protein 9 promotes hepatocellular carcinoma progression via activating the Wnt/β-catenin signaling pathway.
LncAY controls BMI1 expression and activates BMI1/Wnt/β-catenin signaling axis in hepatocellular carcinoma.
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Silent information regulator 2 promotes clear cell renal cell carcinoma progression through deacetylation and small ubiquitin-related modifier 1 modification of glucose 6-phosphate dehydrogenase.
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
TMEM16A, a Homoharringtonine Receptor, as a Potential Endogenic Target for Lung Cancer Treatment.
Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration.
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer.
Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness.
Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/β-catenin pathway in hepatocellular carcinoma.
NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth.
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways.
Niacin stimulates EPH4EV mammary epithelial cell proliferation and mammary gland development in pubertal mice through activation of AKT/mTOR and ERK1/2 signaling pathways.
Expression of COX-2 and Nrf2/GPx3 in the anterior vaginal wall tissues of women with pelvic organ prolapse.
Pyrvinium pamoate can overcome artemisinin's resistance in anaplastic thyroid cancer.
Activity Components from Gynostemma pentaphyllum for Preventing Hepatic Fibrosis and of Its Molecular Targets by Network Pharmacology Approach.
CUX1 Enhances Pancreatic Cancer Formation by Synergizing with KRAS and Inducing MEK/ERK-Dependent Proliferation.
Long intergenic non-coding RNA 00473 promotes proliferation and migration of gastric cancer via the miR-16-5p/CCND2 axis and by regulating AQP3.
Nucleolar and spindle‑associated protein 1 promotes non‑small cell lung cancer progression and serves as an effector of myocyte enhancer factor 2D.
Down-regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p.
LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis.
miRNA in food simultaneously controls animal viral disease and human tumorigenesis.
The influence of phenolic environmental estrogen on the transcriptome of uterine leiomyoma cells: A whole transcriptome profiling-based analysis.
FoxP3-miR-150-5p/3p suppresses ovarian tumorigenesis via an IGF1R/IRS1 pathway feedback loop.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway.
CENPE contributes to pulmonary vascular remodeling in pulmonary hypertension.
ND‑09 inhibits chronic myeloid leukemia K562 cell growth by regulating BCR‑ABL signaling.
Effect of fenofibrate on proliferation of SMMC-7721 cells via regulating cell cycle.
METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
BACH1 is transcriptionally inhibited by TET1 in hepatocellular carcinoma in a microRNA-34a-dependent manner to regulate autophagy and inflammation.
miRNA-194 predicts favorable prognosis in gastric cancer and inhibits gastric cancer cell growth by targeting CCND1.
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis.
Circular RNA-DPP4 serves an oncogenic role in prostate cancer progression through regulating miR-195/cyclin D1 axis.
Long noncoding RNA GAS5 accelerates diabetic wound healing and promotes lymphangiogenesis via miR-217/Prox1 axis.
Maternally expressed 3 protects the intestinal barrier from cardiac arrest-induced ischemia/reperfusion injury via miR-34a-3p/sirtuin 1/nuclear factor kappa B signaling.
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
Absence of the MFG-E8 gene prevents hypoxia-induced pulmonary hypertension in mice.
The circular RNA circZFR phosphorylates Rb promoting cervical cancer progression by regulating the SSBP1/CDK2/cyclin E1 complex.
Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma.
Knockdown of CENPF inhibits the progression of lung adenocarcinoma mediated by ERβ2/5 pathway.
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Sericin inhibits MDA‑MB‑468 cell proliferation via the PI3K/Akt pathway in triple‑negative breast cancer.
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
Synergistic inhibitory effect of Smo inhibitor jervine and its combination with decitabine can target Hedgehog signaling pathway to inhibit myelodysplastic syndrome cell line.
Cell division cycle associated 8: A novel diagnostic and prognostic biomarker for hepatocellular carcinoma.
The protective mechanism of Klotho gene-modified bone marrow mesenchymal stem cells on acute kidney injury induced by rhabdomyolysis.
S100A11 regulates nasal epithelial cell remodeling and inflammation in CRSwNPs via the RAGE-mediated AMPK-STAT3 pathway.
Senescence marker protein 30 inhibits tumor growth by reducing HDAC4 expression in non-small cell lung cancer.
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell.
SETD4 in the Proliferation, Migration, Angiogenesis, Myogenic Differentiation and Genomic Methylation of Bone Marrow Mesenchymal Stem Cells.
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
LncRNA LINC00680 promotes lung adenocarcinoma growth via binding to GATA6 and canceling GATA6-mediated suppression of SOX12 expression.
Hybrid-cell membrane-coated nanocomplex-loaded chikusetsusaponin IVa methyl ester for a combinational therapy against breast cancer assisted by Ce6.
SIRT4 is the molecular switch mediating cellular proliferation in colorectal cancer through GLS mediated activation of AKT/GSK3β/CyclinD1 pathway.
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
THAP11 Functions as a Tumor Suppressor in Gastric Cancer through Regulating c-Myc Signaling Pathways.
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
Cancer Cell enters reversible quiescence through Intracellular Acidification to resist Paclitaxel Cytotoxicity.
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Derlin-1 Promotes the Progression of Human Hepatocellular Carcinoma via the Activation of AKT Pathway.
Up-Regulated CCDC34 Contributes to the Proliferation and Metastasis of Hepatocellular Carcinoma.
ΔNp63α promotes the expression and nuclear translocation of PTEN, leading to cisplatin resistance in oral cancer cells.
Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.
AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.
Activated STAT3 Could Reduce Survival in Patients with Esophageal Squamous Cell Carcinoma by Up-regulating VEGF and Cyclin D1 Expression.
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1.
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.
Aristolochic acid induces renal fibrosis by arresting proximal tubular cells in G2/M phase mediated by HIF-1α.
PAK6 promotes cervical cancer progression through activation of the Wnt/β-catenin signaling pathway.
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
UBAC2 promotes bladder cancer proliferation through BCRC-3/miRNA-182-5p/p27 axis.
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
miR‑483‑3p promotes the osteogenesis of human osteoblasts by targeting Dikkopf 2 (DKK2) and the Wnt signaling pathway.
Oncogenic gene RGC-32 is a direct target of miR-26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling.
Melatonin synergizes BRAF-targeting agent dabrafenib for the treatment of anaplastic thyroid cancer by inhibiting AKT/hTERT signalling.
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells.
PRMT5/Wnt4 axis promotes lymph-node metastasis and proliferation of laryngeal carcinoma.
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26.
Mitochondrial UQCC3 Modulates Hypoxia Adaptation by Orchestrating OXPHOS and Glycolysis in Hepatocellular Carcinoma.
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Metformin suppresses proliferation and invasion of drug-resistant breast cancer cells by activation of the Hippo pathway.
Kp-10 promotes bovine mammary epithelial cell proliferation by activating GPR54 and its downstream signaling pathways.
MS-275 combined with cisplatin exerts synergistic antitumor effects in human esophageal squamous cell carcinoma cells.
MiR-193b-5p inhibits proliferation and enhances radio-sensitivity by downregulating the AKT/mTOR signaling pathway in tongue cancer.
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Increased expression of hematological and neurological expressed 1 (HN1) is associated with a poor prognosis of hepatocellular carcinoma and its knockdown inhibits cell growth and migration partly by down-regulation of c-Met.
Ablation of Gsa impairs renal tubule proliferation after injury via CDK2/cyclin E.
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
ASH2L is involved in promotion of endometrial cancer progression via upregulation of PAX2 transcription.
Radiation-Induced DNMT3B Promotes Radioresistance in Nasopharyngeal Carcinoma through Methylation of p53 and p21.
HnRNP A1 - mediated alternative splicing of CCDC50 contributes to cancer progression of clear cell renal cell carcinoma via ZNF395.
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
miR‑96 exerts an oncogenic role in the progression of cervical cancer by targeting CAV‑1.
Garcinol acts as an antineoplastic agent in human gastric cancer by inhibiting the PI3K/AKT signaling pathway.
PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells.
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
The interaction of tumor cells and myeloid-derived suppressor cells in chronic myelogenous leukemia.
Transcription factor E2F4 is a positive regulator of milk biosynthesis and proliferation of bovine mammary epithelial cells.
Par6 regulates cell cycle progression through enhancement of Akt/PI3K/GSK-3β signaling pathway activation in glioma.
LINC00511 contributes to glioblastoma tumorigenesis and epithelial-mesenchymal transition via LINC00511/miR-524-5p/YB1/ZEB1 positive feedback loop.
SOX6 suppresses the development of lung adenocarcinoma by regulating expression of p53, p21(CIPI) , cyclin D1 and β-catenin.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
TOB1 suppresses proliferation in K-Ras wild-type pancreatic cancer.
Acetyl-11-keto-β-boswellic acid triggers premature senescence via induction of DNA damage accompanied by impairment of DNA repair genes in hepatocellular carcinoma cells in vitro and in vivo.
Pizotifen inhibits the proliferation and invasion of gastric cancer cells.
Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.
Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress.
Heat-Shock protein A12A is a novel PCNA-binding protein and promotes hepatocellular carcinoma growth.
Sirtuin 5 regulates the proliferation, invasion and migration of prostate cancer cells through acetyl-CoA acetyltransferase 1.
Notch3 is involved in the proliferation of renal cancer cells via regulation of cell cycle progression and HIF-2α.
MicroRNA-1236-3p inhibits human osteosarcoma growth.
GEF-independent Ran activation shifts a fraction of the protein to the cytoplasm and promotes cell proliferation.
S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression.
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
TMEM16A-inhibitor loaded pH-responsive nanoparticles: A novel dual-targeting antitumor therapy for lung adenocarcinoma.
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Long Non-coding RNA PEBP1P2 Suppresses Proliferative VSMCs Phenotypic Switching and Proliferation in Atherosclerosis.
Prazosin inhibits the proliferation and survival of acute myeloid leukaemia cells through down-regulating TNS1.
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Celastrol attenuates ox-LDL-induced mesangial cell proliferation via suppressing NLRP3 inflammasome activation.
GRP78 regulates milk biosynthesis and the proliferation of bovinemammaryepithelial cells through the mTOR signaling pathway.
Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.
LncRNA FEZF1-AS1 Promotes TGF-β2-Mediated Proliferation and Migration in Human Lens Epithelial Cells SRA01/04.
Strand-specific miR-28-3p and miR-28-5p have differential effects on nasopharyngeal cancer cells proliferation, apoptosis, migration and invasion.
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Adiponectin Suppresses Human Pancreatic Cancer Growth through Attenuating the β-Catenin Signaling Pathway.
Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
Hypermethylation Of ADHFE1 Promotes The Proliferation Of Colorectal Cancer Cell Via Modulating Cell Cycle Progression.
The effect of MTHFD2 on the proliferation and migration of colorectal cancer cell lines.
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism.
Dimethyl fumarate suppresses hepatocellular carcinoma progression via activating SOCS3/JAK1/STAT3 signaling pathway.
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle.
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension.
NUCKS1 is a novel regulator of milk synthesis in and proliferation of mammary epithelial cells via the mTOR signaling pathway.
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
CircNR3C1 inhibits proliferation of bladder cancer cells by sponging miR-27a-3p and downregulating cyclin D1 expression.
miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells.
Regulation of circadian rhythms by NEAT1 mediated TMAO-induced endothelial proliferation: A protective role of asparagus extract.
HMQ‑T‑F2 suppresses migration of the human cervical cancer HeLa cells by reversing EMT via the PI3K/Akt signaling pathway.
Resveratrol inhibits the proliferation of estrogen receptor-positive breast cancer cells by suppressing EZH2 through the modulation of ERK1/2 signaling.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis.
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
LXRα-mediated downregulation of EGFR suppress colorectal cancer cell proliferation.
RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.
O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion.
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells.
Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM.
Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway.
Agmatinase promotes the lung adenocarcinoma tumorigenesis by activating the NO-MAPKs-PI3K/Akt pathway.
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
piRNA-DQ722010 contributes to prostate hyperplasia of the male offspring mice after the maternal exposed to microcystin-leucine arginine.
Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia.
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
miR-340-FHL2 axis inhibits cell growth and metastasis in ovarian cancer.
MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/β-catenin pathway in acute myeloid leukemia.
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Downregulation of EIF5A2 by miR-221-3p inhibits cell proliferation, promotes cell cycle arrest and apoptosis in medulloblastoma cells.
Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression.
UNBS5162 inhibits SKOV3 ovarian cancer cell proliferation by regulating the PI3K/AKT signalling pathway.
A Molecular Targeted Immunotherapeutic Strategy for Ulcerative Colitis via Dual-targeting Nanoparticles Delivering miR-146b to Intestinal Macrophages.
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability.
CORO1C expression is associated with poor survival rates in gastric cancer and promotes metastasis in vitro.
A miR-567-PIK3AP1-PI3K/AKT-c-Myc feedback loop regulates tumour growth and chemoresistance in gastric cancer.
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation.
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
miR-629-5p promotes growth and metastasis of hepatocellular carcinoma by activating β-catenin.
Thyroid hormone (T(3)) is involved in inhibiting the proliferation of newborn calf Sertoli cells via the PI3K/Akt signaling pathway in vitro.
SND1 promotes the proliferation of osteosarcoma cells by upregulating COX‑2/PGE2 expression via activation of NF‑κB.
Nuclear factor I/B promotes colorectal cancer cell proliferation, epithelial-mesenchymal transition and 5-fluorouracil resistance.
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Regulation of Cell Cycle Regulatory Proteins by MicroRNAs in Uterine Leiomyoma.
Down-regulation of miR-1181 indicates a dismal prognosis for nasopharyngeal carcinoma and promoted cell proliferation and metastasis by modulating Wnt/β-catenin signaling.
Overexpression of SIRT4 inhibits the proliferation of gastric cancer cells through cell cycle arrest.
JTC-801 inhibits the proliferation and metastasis of the Hep G2 hepatoblastoma cell line by regulating the phosphatidylinositol 3-kinase/protein kinase B signalling pathway.
Retracted: Inhibition of microRNA-940 suppresses the migration and invasion of human osteosarcoma cells through the secreted frizzled-related protein 1-mediated Wnt/β-catenin signaling pathway.
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway.
CircCDYL inhibits the expression of C-MYC to suppress cell growth and migration in bladder cancer.
Histone deacetylases inhibitor MS-275 suppresses human esophageal squamous cell carcinoma cell growth and progression via the PI3K/Akt/mTOR pathway.
HOXC13-AS promotes breast cancer cell growth through regulating miR-497-5p/PTEN axis.
MiR-6838-5p suppresses cell metastasis and the EMT process in triple-negative breast cancer by targeting WNT3A to inhibit the Wnt pathway.
MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
LncRNA AC007271.3 promotes cell proliferation, invasion, migration and inhibits cell apoptosis of OSCC via the Wnt/β-catenin signaling pathway.
Paper/polymer composited microfluidic platform for screening cell viability and protein expression under a chemical gradient environment.
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment.
Angiotensin blockade attenuates diabetic nephropathy in hypogonadal adult male rats.
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
(-)-Epicatechin mitigates radiation-induced intestinal injury and promotes intestinal regeneration via suppressing oxidative stress.
RING finger protein 10 is a potential drug target for diabetic vascular complications.
Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway.
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer.
Enhanced expression of circular RNA hsa_circ_000984 promotes cells proliferation and metastasis in non-small cell lung cancer by modulating Wnt/β-catenin pathway.
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo.
Poly(ADP-ribose) Polymerase-1 is required for hepatocyte proliferation and liver regeneration in mice.
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
Exogenous biological renal support ameliorates renal pathology after ischemia reperfusion injury in elderly mice.
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
The Long Noncoding RNA 150Rik Promotes Mesangial Cell Proliferation via miR-451/IGF1R/p38 MAPK Signaling in Diabetic Nephropathy.
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
CircRNA8924 Promotes Cervical Cancer Cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8.
Bushenshugan Formula Attenuates the Development of Lung Cancer by Inhibiting Epithelial-Mesenchymal Transition.
Down-regulation of long non-coding RNA ITGB2-AS1 inhibits osteosarcoma proliferation and metastasis by repressing Wnt/β-catenin signalling and predicts favourable prognosis.
Overexpression of Annexin A2 Receptor Inhibits Neovascularization via the Promotion of Krüppel-Like Transcription Factor 2.
SKA3 promotes cell proliferation and migration in cervical cancer by activating the PI3K/Akt signaling pathway.
VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2.
The protective role of human ghrelin in sepsis: Restoration of CD4 T cell proliferation.
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling.
LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
miR-25 Promotes Melanoma Progression by regulating RNA binding motif protein 47.
Knockdown of Sox2 Inhibits OS Cells Invasion and Migration via Modulating Wnt/β-Catenin Signaling Pathway.
Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis.
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
MiR-1301-3p inhibits human breast cancer cell proliferation by regulating cell cycle progression and apoptosis through directly targeting ICT1.
Aclidinium inhibits proliferation and metastasis of ovarian cancer SKOV3 cells via downregulating PI3K/AKT/mTOR signaling pathway.
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Differential anticancer activities of arsenic trioxide on head and neck cancer cells with different human papillomavirus status.
Mitochondrial ATAD3A regulates milk biosynthesis and proliferation of mammary epithelial cells from dairy cow via the mTOR pathway.
Inhibitory effects of aesculetin on the proliferation of colon cancer cells by the Wnt/β-catenin signaling pathway.
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
The NK1 receptor antagonist NKP608 inhibits proliferation of human colorectal cancer cells via Wnt signaling pathway.
MicroRNA-1247 inhibits cell proliferation by directly targeting ZNF346 in childhood neuroblastoma.
HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer.
CCN1/Cyr61 enhances the function of hepatic stellate cells in promoting the progression of hepatocellular carcinoma.
Actin-capping protein CapG is associated with prognosis, proliferation and metastasis in human glioma.
Annexin A2 positively regulates milk synthesis and proliferation of bovine mammary epithelial cells through the mTOR signaling pathway.
Incorporation of Cerium Oxide into Hydroxyapatite Coating Protects Bone Marrow Stromal Cells Against H(2)O(2)-Induced Inhibition of Osteogenic Differentiation.
Cellular response to persistent foot-and-mouth disease virus infection is linked to specific types of alterations in the host cell transcriptome.
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
MicroRNA-384 inhibits the progression of breast cancer by targeting ACVR1.
Curcumin-Loaded Solid Lipid Nanoparticles Enhanced Anticancer Efficiency in Breast Cancer.
NF-κB and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.
LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial-mesenchymal transition through the Notch1 signaling pathway.
DEAD-box helicase 6 (DDX6) is a new negative regulator for milk synthesis and proliferation of bovine mammary epithelial cells.
UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway.
High expression of TMEM40 is associated with the malignant behavior and tumorigenesis in bladder cancer.
Involvement of mitochondrial fission in calcium sensing receptor-mediated vascular smooth muscle cells proliferation during hypertension.
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Vascular peroxidase 1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation, apoptosis resistance and migration.
YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury.
PTBP3 splicing factor promotes hepatocellular carcinoma by destroying the splicing balance of NEAT1 and pre-miR-612.
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway.
Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
Resveratrol inhibits the growth of gastric cancer via the Wnt/β-catenin pathway.
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
Telmisartan inhibits NSCLC A549 cell proliferation and migration by regulating the PI3K/AKT signaling pathway.
Synergistic effect of receptor-interacting protein 140 and simvastatin on the inhibition of proliferation and survival of hepatocellular carcinoma cells.
Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade.
MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation.
Androgen Receptor Is Inactivated and Degraded in Bladder Cancer Cells by Phenyl Glucosamine via miR-449a Restoration.
Anticancer effect of PP31J isolated from Physalis pubescens L. in human cervical carcinoma cells.
Histone deacetylase inhibitor NaBut suppresses cell proliferation and induces apoptosis by targeting p21 in multiple myeloma.
Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer.
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Therapy Effects of Wogonin on Ovarian Cancer Cells.
Metabolic reprogramming induced by inhibition of SLC2A1 suppresses tumor progression in lung adenocarcinoma.
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
CDKL1 promotes tumor proliferation and invasion in colorectal cancer.
Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer.
Mono-ADP-ribosylation of histone 3 at arginine-117 promotes proliferation through its interaction with P300.
Salusin-β mediates high glucose-induced endothelial injury via disruption of AMPK signaling pathway.
Knockdown of tripartite motif-59 inhibits the malignant processes in human colorectal cancer cells.
Knockdown of Immature Colon Carcinoma Transcript 1 Inhibits Proliferation and Promotes Apoptosis of Non-Small Cell Lung Cancer Cells.
EDIL3 knockdown inhibits retinal angiogenesis through the induction of cell cycle arrest in vitro.
Downregulation of Cohesin Loading Factor Nipped-B-Like Protein (NIPBL) Induces Cell Cycle Arrest, Apoptosis, and Autophagy of Breast Cancer Cell Lines.
Twinfilin 1 enhances milk bio-synthesis and proliferation of bovine mammary epithelial cells via the mTOR signaling pathway.
Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma.
DLEU1 contributes to ovarian carcinoma tumourigenesis and development by interacting with miR-490-3p and altering CDK1 expression.
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Fascaplysin inhibit ovarian cancer cell proliferation and metastasis through inhibiting CDK4.
MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication.
(-)-Curine induces cell cycle arrest and cell death in hepatocellular carcinoma cells in a p53-independent way.
The transcription factor FOXA1 induces epithelial ovarian cancer tumorigenesis and progression.
The soy-derived peptide Vglycin inhibits the growth of colon cancer cells in vitro and in vivo.
High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling.
Involvement of the activation of Nrf2/HO-1, p38 MAPK signaling pathways and endoplasmic reticulum stress in furazolidone induced cytotoxicity and S phase arrest in human hepatocyte L02 cells: modulation of curcumin.
miR-491-5p, mediated by Foxi1, functions as a tumor suppressor by targeting Wnt3a/β-catenin signaling in the development of gastric cancer.
Correlations between TBL1XR1 and recurrence of colorectal cancer.
Methylation of SLFN11 is a marker of poor prognosis and cisplatin resistance in colorectal cancer.
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
ω-3 free fatty acids and all-trans retinoic acid synergistically induce growth inhibition of three subtypes of breast cancer cell lines.
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Methylation of DACT2 promotes breast cancer development by activating Wnt signaling.
Effects of digoxin on cell cycle, apoptosis and NF-κB pathway in Burkitt's lymphoma cells and animal model.
Estrogen receptor-α36 is involved in icaritin induced growth inhibition of triple-negative breast cancer cells.
Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.
Dalbinol, a rotenoid from Amorpha fruticosa L., exerts anti-proliferative activity by facilitating β-catenin degradation in hepatocellular carcinoma cells.
Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.
Galangin suppresses human osteosarcoma cells: An exploration of its underlying mechanism.
H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells.
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Circular RNA 0000096 affects cell growth and migration in gastric cancer.
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway.
Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells.
TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway.
Rhodium (II) complex with 2-benzoylpyridine, a novel potential chemotherapeutic drug, induces cell cycle arrest and apoptosis in HepG2 cells.
MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling.
GRP78 positively regulates estrogen‑stimulated cell growth mediated by ER‑α36 in gastric cancer cells.
Knockdown of Rhotekin 2 expression suppresses proliferation and induces apoptosis in colon cancer cells.
Shrimp miR-34 from Shrimp Stress Response to Virus Infection Suppresses Tumorigenesis of Breast Cancer.
Effects of high-intensity focused ultrasound on cisplatin-resistant human lung adenocarcinoma in vitro and in vivo.
Downregulation of USP32 inhibits cell proliferation, migration and invasion in human small cell lung cancer.
Fangchinoline suppresses the proliferation, invasion and tumorigenesis of human osteosarcoma cells through the inhibition of PI3K and downstream signaling pathways.
Efficient expression of stable recombinant human insulin-like growth factor-1 fusion with human serum albumin in Chinese hamster ovary cells.
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
GOLPH3 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in epithelial ovarian cancer.
The role of MIF, cyclinD1 and ERK in the development of pulmonary hypertension in broilers.
Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis.
The Antitumor Effect of DYC-279 on Human Hepatocellular Carcinoma HepG2 Cells.
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer.
Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib.
Berberine enhances the anti‑tumor activity of tamoxifen in drug‑sensitive MCF‑7 and drug‑resistant MCF‑7/TAM cells.
Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway.
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Knockdown of USP39 induces cell cycle arrest and apoptosis in melanoma.
Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma.
Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance.
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
LSD1 is Required for Hair Cell Regeneration in Zebrafish.
The effects of the 5-HT2A receptor antagonist sarpogrelate hydrochloride on chronic hypoxic pulmonary hypertension in rats.
The AhR is involved in the regulation of LoVo cell proliferation through cell cycle-associated proteins.
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Down-regulation of dihydrofolate reductase inhibits the growth of endothelial EA.hy926 cell through induction of G1 cell cycle arrest via up-regulating p53 and p21(waf1/cip1) expression.
miR-194 inhibits the proliferation, invasion, migration, and enhances the chemosensitivity of non-small cell lung cancer cells by targeting forkhead box A1 protein.
MicroRNA-655-3p functions as a tumor suppressor by regulating ADAM10 and β-catenin pathway in Hepatocellular Carcinoma.
The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR.
Latcripin-13 domain induces apoptosis and cell cycle arrest at the G1 phase in human lung carcinoma A549 cells.
High Expression of XRCC6 Promotes Human Osteosarcoma Cell Proliferation through the β-Catenin/Wnt Signaling Pathway and Is Associated with Poor Prognosis.
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway.
GalNAc-T4 putatively modulates the estrogen regulatory network through FOXA1 glycosylation in human breast cancer cells.
Keratinocyte Growth Factor Regulation of Aryl Hydrocarbon Receptor Activation in Colorectal Cancer Cells.
miRNA-149* promotes cell proliferation and suppresses apoptosis by mediating JunB in T-cell acute lymphoblastic leukemia.
MicroRNA-101 targets von Hippel-Lindau tumor suppressor (VHL) to induce HIF1α mediated apoptosis and cell cycle arrest in normoxia condition.
Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma.
Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling.
Paper-based microreactor array for rapid screening of cell signaling cascades.
PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway.
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways.
RNA interference of Biot2 induces G1 phase arrest and apoptosis in mouse colorectal cancer cell line.
Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway.
Pemetrexed induces G1 phase arrest and apoptosis through inhibiting Akt activation in human non small lung cancer cell line A549.
siRNA-mediated knockdown of JUB expression suppresses the proliferation of glioblastoma cells.
Lentivirus-mediated gene silencing of NOB1 suppresses non-small cell lung cancer cell proliferation.
Doxorubicin-poly (ethylene glycol)-alendronate self-assembled micelles for targeted therapy of bone metastatic cancer.
Low SFRP1 Expression Correlates with Poor Prognosis and Promotes Cell Invasion by Activating the Wnt/β-Catenin Signaling Pathway in NPC.
miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells.
Quercetin reverses experimental pulmonary arterial hypertension by modulating the TrkA pathway.
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
MicroRNA-490-3P targets CDK1 and inhibits ovarian epithelial carcinoma tumorigenesis and progression.
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Knockdown of ANLN by lentivirus inhibits cell growth and migration in human breast cancer.
Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins.
Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.
Capsaicin causes inactivation and degradation of the androgen receptor by inducing the restoration of miR-449a in prostate cancer.
STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer.
Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation.
Gemcitabine resistance in breast cancer cells regulated by PI3K/AKT-mediated cellular proliferation exerts negative feedback via the MEK/MAPK and mTOR pathways.
USP22 promotes the G1/S phase transition by upregulating FoxM1 expression via β-catenin nuclear localization and is associated with poor prognosis in stage II pancreatic ductal adenocarcinoma.
Knockdown of ZFX suppresses renal carcinoma cell growth and induces apoptosis.
Eupolyphaga sinensis Walker inhibits human chronic myeloid leukemia cell K562 growth by inducing G2-M phase cell cycle arrest and targeting EGFR signaling pathway and in S180 tumor-bearing mice.
Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells.
SOX2 regulates apoptosis through MAP4K4-survivin signaling pathway in human lung cancer cells.
Downregulated protein O-fucosyl transferase 1 (Pofut1) expression exerts antiproliferative and antiadhesive effects on hepatocytes by inhibiting Notch signalling.
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma.
MiR-612 suppresses the stemness of liver cancer via Wnt/β-catenin signaling.
Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom.
Hepatitis B viral RNA directly mediates down-regulation of the tumor suppressor microRNA miR-15a/miR-16-1 in hepatocytes.
C1orf61 acts as a tumor activator in human hepatocellular carcinoma and is associated with tumorigenesis and metastasis.
Brucine, an effective natural compound derived from nux-vomica, induces G1 phase arrest and apoptosis in LoVo cells.
Caveolin-1 knockdown is associated with the metastasis and proliferation of human lung cancer cell line NCI-H460.
Li P, Yu X, Wen K, Wang L, Yu J, Chen P
Molecular & cellular oncology 2026;13(1):2604899
Molecular & cellular oncology 2026;13(1):2604899
Pressurized intraperitoneal cold atmospheric plasma as a novel therapeutic strategy for peritoneal metastatic carcinoma.
Min T, Zhang B, Ren K, Ma Y, Ma R, Peng Y, Wang X, Xie X, Deng X, Liu Y, Nan Y, Tong S, Zhang Y, Zhu K, Wei Y, Hao N, Liang C, Wang W, Zhang G, Dang C, Sun T, Zhang H
Journal of advanced research 2026 May;83:991-1004
Journal of advanced research 2026 May;83:991-1004
Kaempferol stimulates dermal papilla cells and upregulates Wnt/β-catenin signaling pathway for androgenetic alopecia treatment.
Zhao C, Jia L, Luo R, Yan H, Li Z, Jiang H, Li Y
The Journal of nutritional biochemistry 2026 Mar;149:110214
The Journal of nutritional biochemistry 2026 Mar;149:110214
Gallium-Doped MXene Nanozymes Protect Liver Through Multi-Death Pathway Blockade and Hepatocyte Regeneration.
Cai X, Deng J, Wang L, Su J, Xian D, Yan Y, Yang X, Wu C, Peng T, Ding Y, Quan G, Wang W, Zhou M, Lu C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e09079
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e09079
Cold Exposure Alleviates Colitis via Parallel Integration of Colonic Mucosal Regeneration and Ileal Antimicrobial Defense.
Di Y, Deng J, Hong Z, Liu Z, Jin L, Zhao W, Qu B
Biomedicines 2026 Mar 9;14(3)
Biomedicines 2026 Mar 9;14(3)
FFAR4 negatively regulates colorectal cancer growth via blocking oxidative phosphorylation.
Wei L, Wei W, Wang Q, Li D, Hu B, Fan F, Liu C, Long P
Journal of translational medicine 2026 Mar 5;24(1)
Journal of translational medicine 2026 Mar 5;24(1)
Downregulation of B7-H4 contributes to the synergistic effect of USP2a-targeted/anti-PD-1 combination therapy in EGFR mutant lung cancer.
Sun B, Kong M, Jiang X, Zhu L, Zhang J, Tan L, Wang C, Yuan Z, Chen S, Wang C, Jiang Y, Zhang L
Cancer immunology, immunotherapy : CII 2026 Mar 26;75(4)
Cancer immunology, immunotherapy : CII 2026 Mar 26;75(4)
The APC/C subunit APC7 promotes hepatocellular carcinoma progression by mediating ubiquitination and degradation of LATS1 to activate YAP/TAZ.
Sun Y, Zhang R, Guo Y, Wu D, Wei H, Tan Z, Huang M, Wang Y, Fang Z, Zhang C, Li C, Li W, Wei D, Bian H, Liu ZK
Biology direct 2026 Mar 23;21(1)
Biology direct 2026 Mar 23;21(1)
B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression.
Lin Y, Zhang Y, Yu B, Wang J, Wu Z, Wang H
Cellular oncology (Dordrecht, Netherlands) 2026 Mar 16;49(2)
Cellular oncology (Dordrecht, Netherlands) 2026 Mar 16;49(2)
Silencing of MAT2A inhibits gastric cancer cell proliferation, migration, and invasion through activation of the p53 pathway.
Du Y, Li KX, You LB, Zhang JN, Chen Q, Xiong H, Wang JF, Zhou ZY, Zhang S
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2026 Jun;28(6):2183-2197
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2026 Jun;28(6):2183-2197
MEHP promotes breast cancer progression via GPR30-mediated epithelial-mesenchymal transition.
Qi W, Wang J, Wang Y, Cui J, Wu X, Ding Z, Jiang T, Liu W, Zhai X, Jin S, Ye L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116049
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116049
Transcriptomic analysis identifies CXCL12 as a novel candidate gene for litter size in rabbits.
Bao Z, Yang J, Li J, Cai J, Zhai P, Zhao P, Zhao B, Chen Y, Wu X
Animal bioscience 2026 Jan;39(1):240640
Animal bioscience 2026 Jan;39(1):240640
SPON2 acts as a tumor promoter in HR-positive/HER2-negative breast cancer by regulating β-catenin signaling.
Liu GY, Huang DP, Ge C, Li XY, Chen F, Fan JS, Tu HP
Clinical breast cancer 2026 Jan;26(1):298-305
Clinical breast cancer 2026 Jan;26(1):298-305
Anti-tumor effect of flavonoids isolated from Bidens Pilosa L. by regulating the activity of myeloid-derived suppressor cells within the tumor microenvironment in mice.
Tao Y, Du M, Zhu M, Sun W, Zeng G, Xiong J, Li J, Yang Z, Fan B, Zhang R, Zeng G
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120635
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120635
Prognostic value of BTG1 for predicting decitabine sensitivity in de novo acute myeloid leukemia.
Zhang S, Li M, Xu B, Zhu X, Mao X, Zhou H, Tong X, Su S, Zhu Y, Zhang D
iScience 2026 Jan 16;29(1):114327
iScience 2026 Jan 16;29(1):114327
MCM8 promotes colorectal cancer progression by competitively inhibiting HRD1-mediated CDC42 ubiquitination and degradation.
Qian S, Zeng L, Chen F, Tian Y, Zhao B, Liu Q, Zhang B
Journal of translational medicine 2026 Jan 16;24(1)
Journal of translational medicine 2026 Jan 16;24(1)
Upregulated ARMCX1 suppresses nasopharyngeal carcinoma progression by promoting TRIM21-mediated β-catenin degradation.
Hu Z, Zhuo E, Guo J, Wu Y, Sun X, Qiu H, Zhou Y, Tan X, Zhang X
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 14;49(1):25
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 14;49(1):25
Mechanism of Babao Dan on fluorouracil-induced bone marrow suppression and T cell immune disorder through MAPK pathway.
Yan S, Sun R, Yuan J, Jia P, Yang R, He J, Guo J, Liu Y, Liu J, Chen X, Lin M, Lin J
Scientific reports 2026 Jan 12;16(1):5057
Scientific reports 2026 Jan 12;16(1):5057
FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo.
Fu Q, Ou Y, Wu Q, Gong J, Li F, Wang T, Lin Z, Huang K, Xie J
International journal of molecular medicine 2026 Feb;57(2)
International journal of molecular medicine 2026 Feb;57(2)
Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells.
Jin L, Wei L, Hua J, Zhang R, Chen J, He J, Yang Y
Oncology reports 2026 Feb;55(2)
Oncology reports 2026 Feb;55(2)
Hexavalent chromium induced autophagy-dependent mTOR expression mediated by upregulation of HMGA2.
Li L, Dan M, Li S, Cui X, Bao S, Luo S, Cao J
Toxicology 2026 Feb;520:154368
Toxicology 2026 Feb;520:154368
Exploring the potential mechanisms of PFAS exposure on colorectal cancer via combined bioinformatics analyses and experiments.
Hao W, Chen X, Xin H, Wang Z, Wen T, Xu D, Ma H
Ecotoxicology and environmental safety 2026 Feb;311:119870
Ecotoxicology and environmental safety 2026 Feb;311:119870
A novel PVA/QCS/AgNP hydrogel with antibacterial and healing-promoting efficacy for preventing postoperative pancreatic fistula in rats.
Zhou Y, Chen F, Lin R, Huang H, Pan M
Colloids and surfaces. B, Biointerfaces 2026 Feb;258:115251
Colloids and surfaces. B, Biointerfaces 2026 Feb;258:115251
Macrophage USP14 suppresses Wnt/β-catenin signaling via NLK deubiquitination to enhance immune response.
Zhao M, Shi J, Wei X, Tian W, Chen Y
Cytokine 2026 Feb;198:157079
Cytokine 2026 Feb;198:157079
Liver-muscle metabolic crosstalk: xanthosine as a key effector of broiler myogenesis.
Chen Y, Ding C, Ren M, Li Z, Liu S, Sun H, Yu S, Niu Q, Li X, Li B, Li L, Yang X, Sun Q
Journal of animal science and biotechnology 2026 Feb 8;17(1):24
Journal of animal science and biotechnology 2026 Feb 8;17(1):24
A human patient-derived organoid biobank to model tumor heterogeneity and therapeutic vulnerability for oral squamous cell carcinoma.
Wang Y, Diao P, Lv P, Qi N, Wang Z, Yan E, Li J, Wang Y, Wang D, Wu Y, Cheng J
Cell reports. Medicine 2026 Feb 17;7(2):102622
Cell reports. Medicine 2026 Feb 17;7(2):102622
Structural characterization and anti-hepatic fibrosis effects of a novel polysaccharide from Astragalus complanatus seeds.
Zhu ZF, Wang SY, Liu XF, Liu N, Dong DC, Qi YC, Li N, Wang N, Tan J, Jia C, Cai RQ, Li XQ, Cao W
Carbohydrate polymers 2026 Feb 1;373:124661
Carbohydrate polymers 2026 Feb 1;373:124661
RARG promotes gastric cancer progression by activating PMEPA1 transcription and Wnt/β-catenin signalling.
Qin L, Wen F, Guo S, Zhang W, Cai W, Ma R, Liu C, Ren W, Ye H, Jiao Z
Cellular signalling 2026 Aug;144:112552
Cellular signalling 2026 Aug;144:112552
TMEM44 as a Novel Prognostic Marker for Hepatocellular Carcinoma is Associated with Tumor Invasion, Migration, and Apoptosis.
Wu Z, Qiu B, Liu S, Hong Y, Sun L, Yin X, Huang Y, Chen Z
Biochemical genetics 2026 Apr;64(2):2764-2781
Biochemical genetics 2026 Apr;64(2):2764-2781
The multilayer coatings on polylactic acid implants spatiotemporally regulates the microenvironment to enhance antibacterial and osseointegration capacity.
Lyu J, Jiang S, Ma T, Zhang Y, Yu J, Zhang Z, Teng Z, Helili M, Cao S, Geng X, Wang X, Jiang J, Qiu J, Sun X, Liu X, Ma X
Materials today. Bio 2026 Apr;37:102871
Materials today. Bio 2026 Apr;37:102871
Nuclear Pirin promotes HCC by acting as a key inflammation-facilitating factor.
Ma H, Cao T, Zhang F, Sun D, Chen L, Lin Y, Lai S, Jiang B, Zhou Y, You J, Liu X, Wang Y, Lin F, Liu Y, Wang J, He W, Li Q
Gut 2026 Apr 7;75(5):1016-1029
Gut 2026 Apr 7;75(5):1016-1029
Sodium-glucose cotransporter 2 inhibitor ameliorates podocyte hypertrophic stress by suppressing the mTOR/p70S6K/cyclin D1 signaling pathway in obesity-related nephropathy.
Suzuki M, Fukuda A, Kurimoto R, Kudo A, Shibata H
Scientific reports 2026 Apr 20;
Scientific reports 2026 Apr 20;
Neddylation of STAT3 is a potential therapeutic target for MASLD.
Liu F, Zhao F, Du M, Ma J, Shang Y, Liu Z, Zhu Y, Zhang Z, Xie P
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 15;1872(6):168261
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 15;1872(6):168261
Phenethyl Isothiocyanate Suppresses Hepatocellular Carcinoma Progression and Immune Evasion via ZNF652 Regulation of PD-L1.
Ren D, Wu J, Zhu J, Xie C, Zhong C, Cao H, Han H, Zhu J
Phytotherapy research : PTR 2026 Apr 15;
Phytotherapy research : PTR 2026 Apr 15;
CYMP-AS1 Promotes Ovarian Cancer Progression by Enhancing the Intracellular Translocation of hnRNPM and Reducing the Stability of AXIN2 mRNA.
Wang Y, Meng Y, Xia W, Liang Y, Wang Y, Li P, Fang L
Oncology research 2025;33(8):2141-2159
Oncology research 2025;33(8):2141-2159
Terpinen-4-ol suppresses proliferation and motility of cutaneous squamous cell carcinoma cells by enhancing calpain-2 expression.
Rong D, Su Y, Zeng Z, Yang Y, Lu H, Cao YU
Oncology research 2025;33(3):605-616
Oncology research 2025;33(3):605-616
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
Peng J, Xue Y, Cai Z, Li Z, Han K, Lin X, Li Y, Zhuo Y
Oncology research 2025;33(10):3127-3154
Oncology research 2025;33(10):3127-3154
Multiaction Antimicrobial, Anti-inflammatory, and Prohealing Hydrogel as a Novel Strategy for Preventing Postoperative Pancreatic Fistula.
Zhou Y, Li L, Chen F, Huang T, Pan M, Huang H
Biomaterials research 2025;29:0194
Biomaterials research 2025;29:0194
Tobacco carcinogen NNK promotes pancreatic cancer proliferation via LINC00857/β-catenin.
Zhou C, Cao R, Wang Q, Mo J, Qian W, Feng Z, Zhang S, Chen X, Hao J, Ma Q, Wu Z, Wang Z
Tobacco induced diseases 2025;23
Tobacco induced diseases 2025;23
DNMT3a promotes LUAD cell proliferation and metastasis by activating the HDAC7 signalling pathway.
Jiang M, Zhou X, Feng Y, Ding P, Li J, Lu D, Qin J, Bai Y, Wang A, Xia C, Wang J, Yan X, Ma Z, Zhang R
International journal of biological sciences 2025;21(4):1585-1602
International journal of biological sciences 2025;21(4):1585-1602
Mechanism of Curcumin in Inhibiting Proliferation of Head and Neck Squamous Cell Carcinoma: A Network Pharmacology and Cellular Experimental Study.
He Y, Liao Y, Fang S, Zhu L, Zhao Z, Chen T, Zhang Z
BioMed research international 2025;2025:4318115
BioMed research international 2025;2025:4318115
Inhibition of PHB1/PHB2 suppresses atherosclerotic plaque formation by interrupting PI3K/AKT/mTOR signaling.
Li M, Hu X, Hu X, Gao F, Cui Y, Wei X, Qin Y, An X, Zhao Y, Gao Y
PloS one 2025;20(4):e0320509
PloS one 2025;20(4):e0320509
FAM50A as a novel prognostic marker modulates the proliferation of colorectal cancer cells via CylinA2/CDK2 pathway.
Li L, Ji Z, Li G, Gu H, Sun Y
PloS one 2025;20(2):e0318776
PloS one 2025;20(2):e0318776
STAG2 mutations in the normal colon induce upregulation of oncogenic pathways in neighbouring wildtype cells.
Yew WN, Dean CJ, Chan DKH
PloS one 2025;20(10):pone.0332499.exml
PloS one 2025;20(10):pone.0332499.exml
DDIAS promotes endometrial cancer progression via β-catenin signaling.
Tian X, Liu M, Zhao J, Lao C, Liu B, Suo Y
PloS one 2025;20(10):e0331851
PloS one 2025;20(10):e0331851
Hepatic Stellate Cell TM4SF1 Accelerates Hepatic Fibrosis Progression via Interacting With the Tyrosine Kinase c-Src.
Liu S, Tan P, Chen J, Huang Z, Ren B, Jiang Z, Gu B, Yu W, Sun L, Chen Y, Ruan J, Fu W
Cellular and molecular gastroenterology and hepatology 2025;19(10):101559
Cellular and molecular gastroenterology and hepatology 2025;19(10):101559
Leonurine Attenuates CCl(4)-Induced Hepatic Fibrosis in Mice via the Hippo-YAP Pathway.
Wang P, Bai J, Ye M, Huang Z, Chen J, Sun L, Zhong X, Zheng Y, Ma T, Fu W, Du Y
Drug design, development and therapy 2025;19:6553-6571
Drug design, development and therapy 2025;19:6553-6571
Bavachin suppresses proliferation of laryngopharyngeal cancer by regulating the STAT3 and MAPK signaling pathways.
Yang X, Ding Z, Hua H, Gan R, Meng D, Zang Y, Xiao H, Wang D, Jiang W, Si D, Wei X, Zhang M, Zhang H, Gao C
Journal of Cancer 2025;16(7):2339-2352
Journal of Cancer 2025;16(7):2339-2352
EIF4A3 Promotes Cell Proliferation via CDC5L Upregulation in Human Breast Cancer Cells.
Zhang M, Xie Y, Song S, Wang R, Chen H, Li Y, Liu J, Li J, Jiang Y, Liu P, Wang B
Journal of Cancer 2025;16(6):1958-1970
Journal of Cancer 2025;16(6):1958-1970
Capsaicin, the Pungent Component of Red Chili Pepper, induces p21-mediated Cell Cycle Arrest in Renal Cell Carcinoma via Downregulating GLI1: an Experimental Research In Vitro.
Zheng L, He Y, Huang H, Qu W
Journal of Cancer 2025;16(15):4284-4291
Journal of Cancer 2025;16(15):4284-4291
CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation.
Li J, Wang N, Bi J, Guo M, Xu B, Huang G
Frontiers in genetics 2025;16:1687066
Frontiers in genetics 2025;16:1687066
Identification of an Ara-C resistance-related gene risk score and the role of S100A4 in AML via NR6A1-dependent activation and p53 regulation.
Wang L, Huang A, Cheng B, Hu X, Wang J
Frontiers in pharmacology 2025;16:1574759
Frontiers in pharmacology 2025;16:1574759
Dissecting the multi-omics landscape of TEAD1 in hepatocellular carcinoma: cycle regulation and metastatic potential.
Huai R, Mao C, Xiong L
Frontiers in immunology 2025;16:1567969
Frontiers in immunology 2025;16:1567969
Stimulation of regulatory dendritic cells suppresses cytotoxic T cell function and alleviates DEN-induced liver injury, fibrosis and hepatocellular carcinoma.
Wang J, Gong P, Liu Q, Wang M, Wu D, Li M, Zheng S, Wang H, Long Q
Frontiers in immunology 2025;16:1565486
Frontiers in immunology 2025;16:1565486
Inhibition of colorectal cancer cell growth by downregulation of M2-PK and reduction of aerobic glycolysis by clove active ingredients.
Liu L, Xing G, Guo X, Chen H, Li J, Wang J, Li Y, Liang G, Liu M
Frontiers in pharmacology 2025;16:1552486
Frontiers in pharmacology 2025;16:1552486
The type I ribosome-inactivating protein α-MMC induced significant apoptosis of lung cancer A549 and 95-D cells by activating the caspase cascade through TNF signaling pathway.
Yang D, Peng D, Li H, Jia D, Zhou Y, Hu B, Chen W, Meng Y
Frontiers in pharmacology 2025;16:1529151
Frontiers in pharmacology 2025;16:1529151
The regulatory role of the circELMOD3-associated ceRNA network in the progression and prognosis of hepatocellular carcinoma.
Li D, Liu M, Lai M, Wang L, Wei L, Wu S, Liang S, Liu S, Zeng X
Frontiers in genetics 2025;16:1521360
Frontiers in genetics 2025;16:1521360
Developing a prognostic stratification model based on glutathione metabolism in thyroid cancer and validating RRM2's tumor-promoting role.
Ao W, Liu TH, Yin DT, Zhao WX
Frontiers in oncology 2025;15:1700439
Frontiers in oncology 2025;15:1700439
RBP7 knockdown inhibits proliferation of human hepatocellular carcinoma and activates the p38 MAPK pathway.
Li J, Zhai H, Cai F, Zhang X, Zhou Y, Li S, Song H, Zhang H, Sun G, Zhu M, Yuan J, Zhang N, Yan M
Frontiers in oncology 2025;15:1592616
Frontiers in oncology 2025;15:1592616
MiR-145-5p arrests the cell cycle by modulating SMAD5/cyclin D1 to inhibit gastric cancer progression.
Wang L, Guo J, Lv C, Kong L, Cui J, Wang Z, Guo Y, Jia R, Guan T, Yu B, Li F
Frontiers in cell and developmental biology 2025;13:1619359
Frontiers in cell and developmental biology 2025;13:1619359
Ginsenoside Rg5 enhances Abemaciclib sensitivity in ER+ breast cancer by modulating cell cycle proteins via transcriptional and post-translational levels.
Chen J, Liao D, Wu C, Liu L, Luo J, Li G, Cao L
Journal of ginseng research 2025 Sep;49(5):594-603
Journal of ginseng research 2025 Sep;49(5):594-603
METTL3 Mediates Wnt/β-Catenin Pathway in Epithelial-Mesenchymal Transition of 16HBE Cells Induced by Beryllium Sulphate.
Yan C, Li G, Huang L, Zhang Z
Journal of applied toxicology : JAT 2025 Sep;45(9):1787-1797
Journal of applied toxicology : JAT 2025 Sep;45(9):1787-1797
SIX1 transmits signals for breast cancer progression via the ZEB1/IL6/STAT3 signaling axis.
Guo L, Rao Y, Song Y, Hu J, Luo Z, Sun S, Chen C, Kong D
Oncogene 2025 Sep;44(37):3493-3511
Oncogene 2025 Sep;44(37):3493-3511
KDM4C regulates trophoblast proliferation and migration in preeclampsia via the NFATc4/Wnt pathway.
Shao C, Jia Y, Qiao S, Gao Q, He T, Meng Y, He J, Shan Y
International journal of biological macromolecules 2025 Sep;321(Pt 3):146320
International journal of biological macromolecules 2025 Sep;321(Pt 3):146320
SARS-CoV-2 nucleocapsid protein delays cell cycle in S-phase.
Liu J, Liu M, Yu X, Wang PH, Guan X, Huo W, Zhang J, Cui M, Li X, Zhou X, Liu S, Wang C, Huang C, Yu J
International journal of medical microbiology : IJMM 2025 Sep;320:151671
International journal of medical microbiology : IJMM 2025 Sep;320:151671
The chromatin remodeling factor BAP18 promotes non-small cell lung cancer progression via the recruitment of β-catenin with the transcriptional coactivator complex ACTL6A-PAF1.
Hao J, Hu Q, Li X, Shi S, Na F, Zeng K, Li H, Zhao Y, Zhao M
The Journal of biological chemistry 2025 Sep;301(9):110596
The Journal of biological chemistry 2025 Sep;301(9):110596
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
Huang QH, Tang XY, Huang QY, Zhi SB, Zheng XQ, Gan CY, Huang MF, Pan ZF, Zhong ZX
Biochemical pharmacology 2025 Sep;239:117014
Biochemical pharmacology 2025 Sep;239:117014
TSZAF monomer combination downregulates the Wnt/β-catenin signaling pathway and inhibits neutrophil recruitment to prevent lung cancer metastasis.
Yu P, Yao J, Zhang L, Wang Y, Lu X, Liu J, Que Z, Liu Y, Ba Q, Liu J, Wu Y, Tian J
Chinese journal of natural medicines 2025 Sep;23(9):1069-1079
Chinese journal of natural medicines 2025 Sep;23(9):1069-1079
Magnolin Promotes PINK1-Parkin-mediated Mitophagy in Diffuse Large B-cell Lymphoma Cells via PPAR-γ Pathway.
Zhou X, Guo Q, Qiao Q, Fang X, Jiang Y, Wang X, Hu S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157059
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157059
H3K36me3-Guided m(6)A Modification of Oncogenic L1CAM-AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma.
Wang T, Han L, Huo Y, Zhang L, Huang Y, Zhang N, Yang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
Inhibition of ICAM1 diminishes stemness and enhances antitumor immunity in glioblastoma via β-catenin/PD-L1 signaling.
Guo M, Yuan Z, Jin X, Li X, Deng Y, Zhou S, Niu R, Bae J, Park JB, Shi B, Yin J
Nature communications 2025 Sep 30;16(1):8642
Nature communications 2025 Sep 30;16(1):8642
MSCs-EXOs containing miR-21a-5p promoted cell proliferation in the rat retinal Müller cell rMC-1 via targeting LATS1.
Deng L, Wang Y
Stem cell research & therapy 2025 Sep 29;16(1):529
Stem cell research & therapy 2025 Sep 29;16(1):529
Pracinostat inhibits the nefarious biological behavior of pancreatic cancer by targeting the miR-381-3p/MDM2 axis to activate the p53 signaling pathway.
Cun D, Liu F, Tian D, Li T, Guo Z, Chen P
Pathology, research and practice 2025 Oct;274:156186
Pathology, research and practice 2025 Oct;274:156186
Effect of rumen-protected guanidinoacetic acid provision as a dietary supplement on the growth, slaughter performance, and meat quality in simmental bulls.
Zhang J, Xue C, Lang J, Pei C, Liu Q
Meat science 2025 Oct;228:109889
Meat science 2025 Oct;228:109889
Prrx1 promotes mesangial cell proliferation and kidney fibrosis through YAP in diabetic nephropathy.
Xu L, Shi J, Li H, Liu Y, Wang J, Li X, Ren D, Liu S, Wang H, Lu Y, Song J, Du L, Lu Q, Yin X
Journal of pharmaceutical analysis 2025 Oct;15(10):101247
Journal of pharmaceutical analysis 2025 Oct;15(10):101247
METTL3-mediated modification of SIRT1 m6A methylation protects osteoblasts from TBHP-induced senescence and promotes osteoblast proliferation.
Chen Y, Wang Y, Xiao H, Teng F, Yang A, Liu J, Liu Z, Sheng X, Zhang C, Zhang S, Geng B, Xia Y
Chemico-biological interactions 2025 Oct 22;420:111672
Chemico-biological interactions 2025 Oct 22;420:111672
Comprehensive evaluation of the PCDHB family in gastric cancer: Prognostic significance, immune infiltration, and experimental validation of PCDHB5's oncogenic role.
Zhou J, Zhan J, Zhang H, Liu L, He Y, Le Y, Liu W, Zhou L, Xiang X
International immunopharmacology 2025 Oct 10;163:115318
International immunopharmacology 2025 Oct 10;163:115318
BATF2-mediated control of astrocyte proliferation.
Tinkey RA, Frostino BJ, Habean ML, Williams JL
The Journal of biological chemistry 2025 Nov;301(11):110710
The Journal of biological chemistry 2025 Nov;301(11):110710
Integrating network pharmacology and pharmacological evaluation for investigating the active ingredient of Chinese herbal formula Zhuhuang Granule in psoriasis.
Wang J, Luo M, Zhang Y, Pan Y, Huang P, Zhou R, Yan Y, Wang B, Jiang M, Ran C, Wang H
Pathology, research and practice 2025 Nov;275:156201
Pathology, research and practice 2025 Nov;275:156201
Dendrobin A inhibits gastric cancer: Mechanistic insights supported by integrated evidence.
Fan Y, Chen Y, Lu W, Shi K, Zhao Y, Zhang C, Shen Z, Zheng S, Jie W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157215
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157215
DDX1 facilitates lenvatinib resistance in hepatocellular carcinoma through regulating ephrin-A3 and activating the Wnt/β-catenin signaling pathway.
Huang S, Wang H, Fu S, Cheng F, Liu K, Wu J
Functional & integrative genomics 2025 Nov 4;25(1):230
Functional & integrative genomics 2025 Nov 4;25(1):230
Uridine-cytidine kinase 2 as a novel potential prognostic and therapeutic biomarker in gastric cancer.
Sun W, Guo H, Cai M, Ma G, Zhang L, Yu Y, Zhan H
Translational cancer research 2025 Nov 30;14(11):8070-8085
Translational cancer research 2025 Nov 30;14(11):8070-8085
Sorting nexin 9 expression and prognostic implications in lung adenocarcinoma: integrative bioinformatic and in vitro validation.
Liu W, Yin Y, Wang B, Li T, Chen J
Translational cancer research 2025 Nov 30;14(11):7480-7493
Translational cancer research 2025 Nov 30;14(11):7480-7493
RTA-408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma.
Tsai HP, Qin H, Chong YB, Chen IH, Kuo SH, Tseng TT, Lieu AS
The Kaohsiung journal of medical sciences 2025 Nov 28;:e70142
The Kaohsiung journal of medical sciences 2025 Nov 28;:e70142
Histone demethylase KDM9 activates the CCND1/AKT pathway to promote the malignant progression of gliomas through interaction with BRD2.
Cheng J, Peng X, Tang S, Zhou P, Zhou Z, Mao Z, Li D, Yang L, Peng J
Cellular and molecular life sciences : CMLS 2025 Nov 26;82(1):423
Cellular and molecular life sciences : CMLS 2025 Nov 26;82(1):423
An integrated study on the role and underlying mechanism of QingFei Oral solution in pulmonary hypertension.
Zou X, Cai A, Cheng Y, Li X, Chen Y, Li W, Zhang Y, Pan Z, Liu Y, Zhang Y, Liu T, Huang P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157311
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157311
ZNF526 drives tumor growth by enhancing SHMT1-dependent serine metabolism and antioxidant capability in TNBC.
Qin W, Shao L, Li Q, Zhang D, Jia X, Dong C
Molecular cancer 2025 Nov 20;24(1):295
Molecular cancer 2025 Nov 20;24(1):295
CDC26 facilitates ferroptosis through SLC7A11 degradation and cell cycle arrest.
Lin J, Chen F, Tang H, Cai X, Huang M, Liang R, Kang R, Tang D, Liu J
Clinical and experimental medicine 2025 Nov 18;26(1):11
Clinical and experimental medicine 2025 Nov 18;26(1):11
Distinct functional heterogeneity of TP53 R175 mutations in platinum-resistant ovarian cancer: unveiling molecular mechanisms and therapeutic targets.
Liu Y, Zheng Z, Ni M, Mao S, Xiao Y, Zhao Y, Tian B, Wang L, Xu H, Hua Y
Cell death & disease 2025 Nov 17;16(1):837
Cell death & disease 2025 Nov 17;16(1):837
Knockdown of SUCLG2 inhibits glioblastoma proliferation and promotes apoptosis through LMNA acetylation and the mediation of H4K16la lactylation.
Li W, Zhang Q, Yin H, Li Q, Liu S, Wang J, Yuan G, Pan Y
Cell death discovery 2025 Nov 17;11(1):534
Cell death discovery 2025 Nov 17;11(1):534
Genome-wide mapping of EBV-induced genomic variations identifies the role of MUC19 in EBV latency.
Yu J, Wang Y, Liu Q, Zhou X, Robertson ES, Pei Y
mBio 2025 Nov 12;16(11):e0205525
mBio 2025 Nov 12;16(11):e0205525
Exploring the mechanism of baicalein on breast cancer based on network pharmacology, molecular docking and in vivo experiments.
Zhang G, Liu Z, Xu Y, Cao F, Huo X, Chen Q, Luo D
Toxicology and applied pharmacology 2025 May;498:117297
Toxicology and applied pharmacology 2025 May;498:117297
Deletion of smooth muscle ZFP36 promotes neointimal hyperplasia in mice.
Wang L, He LF, Xiong X, Wu ZN, Tian M, Cao GQ, Lu HX, Ji XP, Zhang YL, Kovarik P, Zhang W, Liu Y
Acta pharmacologica Sinica 2025 May;46(5):1317-1328
Acta pharmacologica Sinica 2025 May;46(5):1317-1328
COL1A1 promotes cell proliferation, cell cycle progression, and anoikis resistance in granulosa cells of chicken pre-ovulatory follicles.
Li X, Luo X, Zhang X, Guo Y, Cheng L, Cheng M, Tang S, Gong Y
International journal of biological macromolecules 2025 May;306(Pt 2):141524
International journal of biological macromolecules 2025 May;306(Pt 2):141524
HKDC1 promotes colorectal cancer progression by regulating RCOR1 expression to activate the Wnt/β-catenin pathway, enhancing proliferation, migration, and epithelial-mesenchymal transition.
Huang S, Pang Q, Zhang Y, Cao J
The Journal of biological chemistry 2025 May;301(5):108478
The Journal of biological chemistry 2025 May;301(5):108478
The Role of PAX7 in Breast Cancer Prognosis and Its Mechanistic Involvement in the Wnt/β-Catenin Pathway.
Ge Q, Zhang W, Li C, Li X, Wang Z, Li X
Journal of cellular and molecular medicine 2025 May;29(10):e70602
Journal of cellular and molecular medicine 2025 May;29(10):e70602
AMPKα alleviates the inhibitory effect of NEFA on the function of bovine follicular granulosa cells cultured in vitro.
Zhao C, Xu R, Xin S, Jiang B, Feng S, Wang X, Xia C
Animal reproduction science 2025 May;276:107831
Animal reproduction science 2025 May;276:107831
Integrated multi-omics characterization of neuroblastoma with bone or bone marrow metastasis.
Huang K, Yang L, Ma Y, Cao L, Li S, Zhao Z, Zhou J, Wang S
Genes & diseases 2025 May;12(3):101511
Genes & diseases 2025 May;12(3):101511
Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low-Temperature Photothermal Therapy via Targeting HSP90-TXNDC9 Interactions.
He D, Chen S, Wang X, Wen X, Gong C, Liu L, He G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2412953
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2412953
Transglutaminase 2 nuclear localization enhances glioblastoma radiation resistance.
Sun C, Du Z, Yang W, Wang Q
Discover oncology 2025 May 30;16(1):952
Discover oncology 2025 May 30;16(1):952
Mechanosensitive Piezo1 channel is highly expressed in the age-induced fibrotic uterus.
Wang Y, Liu X, Wang M, Kang J, Zhang Y
Molecular biology reports 2025 May 28;52(1):510
Molecular biology reports 2025 May 28;52(1):510
Targeting of the IL-33/Wnt axis restricts breast cancer stemness and metastasis.
Fan G, Zuo S, Wang Z, Zhang S, Liu L, Luo H, Xie Y, Zhang Y, Li D
Scientific reports 2025 May 25;15(1):18172
Scientific reports 2025 May 25;15(1):18172
MiR-485-3p/MELK cascade mediates tumor progression in pancreatic cancer.
Huang Y, Yang T, Yang C, Tang B, Su B, Yang X
Scientific reports 2025 May 22;15(1):17870
Scientific reports 2025 May 22;15(1):17870
Study on the molecular mechanism of UBA52 and BARD1 regulating hepatocellular carcinoma through the PI3 K/AKT signaling pathway.
Yang C, Zhang Y, Liu Y, Wu X, Sun F
Discover oncology 2025 May 21;16(1):840
Discover oncology 2025 May 21;16(1):840
Anlotinib enhances the efficacy of KRAS-G12C inhibitors through c-Myc/ORC2 axis inhibition in non-small cell lung cancer.
Liu H, Zhou C, Lu J, Liu Y, Zou P, Zhu L, Lei H, Han B
Cell death & disease 2025 May 2;16(1):356
Cell death & disease 2025 May 2;16(1):356
Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Expression and Promotes Cell Proliferation through Reduction of Apoptosis.
Zhang HJ, Zhao Q, Zhang M, Yang LL, Abiti J, Han MM, Gao YP, Lu JT, Wang JN, Ji MY, Zhang X, Wang W, Qiu LL, Wang XY, Wang TY, Jia YL
ACS synthetic biology 2025 May 16;14(5):1802-1812
ACS synthetic biology 2025 May 16;14(5):1802-1812
YTHDF1-targeting nanoassembly reverses tumoral immune evasion through epigenetics and cell cycle modulation.
Liu H, Zhang X, Ding F, Pan J, Zhu H, Zhou Z, Sun M
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113574
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113574
SNORD9 promotes ovarian cancer tumorigenesis via METTL3/IGF2BP2-mediated NFYA m6A modification and is a potential target for antisense oligonucleotide therapy.
Chen S, Wen JT, Zhang S, Wang JL, Yuan J, Bao HJ, Chen X, Zhao Y
Life sciences 2025 May 1;368:123527
Life sciences 2025 May 1;368:123527
Penta-1,4-dien-3-one and quinoxaline conjugates as potential anticancer agents via inhibiting EphB3/SRC/AKT axis.
Li Q, Zhou M, Yang Y, Jiang Y, Chen C, Hu E, Chen J, Wang D
Life sciences 2025 May 1;368:123510
Life sciences 2025 May 1;368:123510
Liraglutide improves senescence and ameliorating diabetic sarcopenia via the YAP-TAZ pathway.
Xu Q, Qiu X, Di H, Li Z, Liu Z, Liu K
Journal of diabetes and its complications 2025 Mar;39(3):108975
Journal of diabetes and its complications 2025 Mar;39(3):108975
The MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.
Wang J, Li X, Zhao L, Fan X, Cao J, Wang S, Li K, Wang H, Zhang Y, Wang H, Xu C, Ding L, Che T, Chen S, Yang L
International journal of biological macromolecules 2025 Mar;296:139777
International journal of biological macromolecules 2025 Mar;296:139777
HOGA1 Suppresses Renal Cell Carcinoma Growth via Inhibiting the Wnt/β-Catenin Signalling Pathway.
Wang C, Liu Y, Tan Y, Xu F, Wang M, Tang Y, Nie G, Chi X, Xu Z, Xu Y, An B, Tian G, Qi D, Yao C
Journal of cellular and molecular medicine 2025 Mar;29(6):e70490
Journal of cellular and molecular medicine 2025 Mar;29(6):e70490
GAS41 promotes ITGA4-mediated PI3K/Akt/mTOR signaling pathway and glioma tumorigenesis.
Shang G, Zhang W, Jia Y, Ji D, Wei E, Gao C, Zeng C, Wang C, Liu N, Ge P, Li Y, Zeng L
Biochemical pharmacology 2025 Mar;233:116747
Biochemical pharmacology 2025 Mar;233:116747
SEPT5 overexpression predicts poor prognosis and promotes progression through feedback regulation of HIF-1α in clear cell renal cell carcinoma.
Liu W, Ni Y, Wang W, Cui K, Duan Q, Bai Z, Shahzad A, Liu X, Dong Y, Xu Z, Zhang J, Peng D, Teng Z, Gao Y, Yang Z, Zhang Q
Cellular signalling 2025 Mar;127:111591
Cellular signalling 2025 Mar;127:111591
CTSG restraines the proliferation and metastasis of head and neck squamous cell carcinoma by blocking the JAK2/STAT3 pathway.
Hua H, Yang X, Meng D, Gan R, Chen N, He L, Wang D, Jiang W, Si D, Wang X, Zhang X, Wei X, Wang Y, Li B, Zhang H, Gao C
Cellular signalling 2025 Mar;127:111562
Cellular signalling 2025 Mar;127:111562
The LncRNA lnc-POTEM-4:14 promotes HCC progression by interacting with FOXK1.
Peng B, Quan Z, Liang L, Liu M, Hu K, Chen S, Xie Q, Qin J, Chen J, Liao L, He S, Li Z
Scientific reports 2025 Mar 5;15(1):7672
Scientific reports 2025 Mar 5;15(1):7672
Enhancing KRAS G12D inhibitor sensitivity in pancreatic cancer through SHP2/PI3K pathway.
Hao MW, Zhang TX, Dong D, Zhou X, Gao H
Medical oncology (Northwood, London, England) 2025 Mar 27;42(5):139
Medical oncology (Northwood, London, England) 2025 Mar 27;42(5):139
c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy.
Wang Y, Huang J, Song Z, Zhang S, Guo H, Leng Q, Fang N, Ji S, Yang J
Biology direct 2025 Mar 27;20(1):37
Biology direct 2025 Mar 27;20(1):37
TMEM176B inhibits ovarian cancer progression by regulating EMT via the Wnt/β-catenin signaling pathway.
Yan L, Song Z, Yi L, Tian C, Zhang R, Qin X, Wang X, Ren S, Ma X, Wang X, Zhao X, Wang F, Wei J, Jia X, Gu M, Yuan F, Jia D
Journal of translational medicine 2025 Mar 19;23(1):350
Journal of translational medicine 2025 Mar 19;23(1):350
HSPD1-facilitated formation of CTPS cytoophidia promotes proliferation in C2C12 cells.
Liu L, Chen W, Luo H, Zhang W, Zhang Z, Huang X, Fu X
Experimental cell research 2025 Mar 1;446(1):114462
Experimental cell research 2025 Mar 1;446(1):114462
Tasquinimod promotes the sensitivity of ovarian cancer cells to cisplatin by down-regulating the HDAC4/p21 pathway.
Li Z, Wu YH, Guo YQ, Min XJ, Lin Y
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 Mar 1;29(2):191-204
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 Mar 1;29(2):191-204
Targeting DUSP3 promotes cell senescence by activating the notch1 pathway to treat hepatocellular carcinoma.
Zhang WJ, Peng JL, Dai DF, Huang C, Chen XP
Tissue & cell 2025 Jun;94:102781
Tissue & cell 2025 Jun;94:102781
Rictor orchestrates β-catenin/FOXO balance by maintaining redox homeostasis during development of ovarian cancer.
Zhao X, Lai H, Li G, Qin Y, Chen R, Labrie M, Stommel JM, Mills GB, Ma D, Gao Q, Fang Y
Oncogene 2025 Jun;44(23):1820-1832
Oncogene 2025 Jun;44(23):1820-1832
A novel piperine derivative HJ-23 exhibits anti-colorectal cancer effects by activating the p53 pathway.
Zhang M, Liu R, Jiang W, Li H, Zhang S, Cheng W, Ye X, He J, Liu Y, Jing A, Song Y, Wang D, Liu X, Zhang B, Wang X, Ji J
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jun;398(6):7121-7131
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jun;398(6):7121-7131
Impacts of dietary arginine supplementation on performance, nutrient digestion and expression of proteins related to milk fatty acid and casein synthesis in early lactating dairy cows.
Zhang J, Lang J, Bu L, Liu Y, Huo W, Pei C, Liu Q
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Jun;21:267-278
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Jun;21:267-278
Targeting the MDK/c-Myc complex to overcome temozolomide resistance in glioma.
Xi X, Ding X, Wang Q, Liu N, Wang B, Wang G, Zhong W, Lu Y
Clinical and translational medicine 2025 Jun;15(6):e70359
Clinical and translational medicine 2025 Jun;15(6):e70359
Effect of COL11A1 on oral squamous cell carcinoma.
Liu YH, Li D, Zhang HL, Zhang BH, Song WJ, Li TK
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3S):102183
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3S):102183
MAT2A Knockdown Enhances Recombinant Protein Expression in Transgenic CHO Cells Through Regulation of Cell Cycle.
Gao YP, Lu JT, Zhang HJ, Cui ZM, Guo Y, Zhang X, Wang W, Qiu LL, Wang XY, Wang TY, Jia YL
Biotechnology and bioengineering 2025 Jun;122(6):1461-1471
Biotechnology and bioengineering 2025 Jun;122(6):1461-1471
Suppression of MRPL23 induces cellular senescence in hepatocellular carcinoma by targeting HMGB1.
Huang YB, Xu SM, Li M, Chen J, Lu CH, Liu QQ
Discover oncology 2025 Jun 9;16(1):1041
Discover oncology 2025 Jun 9;16(1):1041
Apigenin prevents hypertensive vascular remodeling by regulating the TP53 pathway.
Gao J, Wang D, Zhang X, Yang G, Xi D, Qin X, Wang Y, Jin Y, Guo Y, Li X, Ma K
International immunopharmacology 2025 Jun 5;157:114706
International immunopharmacology 2025 Jun 5;157:114706
Serine/threonine/tyrosine kinase 1 drives pancreatic carcinogenesis via GSK3β sequestration-mediated Wnt/β-catenin pathway hyperactivation.
Zhou C, Dong X, Li S, Xi Y, Liu Y, Qian X, Song Z, Zhou L, Zhang R, Lyu H, Xiao S, Guo D, Zhang Q, Liu W, Xiong Y, Wang Z, Yan C, Zhang Z, Zhu H, Chen XZ, Song Z, Tang J
Signal transduction and targeted therapy 2025 Jun 30;10(1):205
Signal transduction and targeted therapy 2025 Jun 30;10(1):205
FSTL3 promotes colorectal cancer by activating the HIF1 pathway.
Luo XR, Huang LZ, Yin J, Xiong ZM, Li WX, Liao C, Lin ML, Huang W, Zhang S
Gene 2025 Jun 20;954:149435
Gene 2025 Jun 20;954:149435
Study on the role of miR-10b-3p as SASP in exosomes of premature senescent hepatocytes induced by hexavalent chromium.
Liang Q, Huang Z, Wang D, Xin F, Xu J, He J, Luo R, Zeng Y, Ma Y
Ecotoxicology and environmental safety 2025 Jun 15;298:118333
Ecotoxicology and environmental safety 2025 Jun 15;298:118333
Genome-guided discovery of coublibactins from Nocardia coubleae and their gallium complexes with potent antileukemic activity.
Tao Q, Cai T, Xiao Y, Han T, Shen L, Cheng C, Xu S, Li A, Zhang P, Chen J, Zhang Y, Tong Q, Cai X
Bioorganic chemistry 2025 Jun 15;160:108508
Bioorganic chemistry 2025 Jun 15;160:108508
HNF4A promotes tumor progression in gastric cancer by transcriptional activation of KIF2C.
Lu H, Gan JH, Zhou LQ, Yuan YW, Zhou Q, Xin L
Clinical and experimental medicine 2025 Jun 14;25(1):205
Clinical and experimental medicine 2025 Jun 14;25(1):205
Glycyrrhizic acid promotes liver regeneration through activating β-catenin in acetaminophen-induced liver injury.
Cao R, Gong H, Xia S, Hu Z, Fan X, Zhai B, Guo L, Xia C, Jiang Z, Yan M
Journal of ethnopharmacology 2025 Jun 12;349:119895
Journal of ethnopharmacology 2025 Jun 12;349:119895
Modulation of copper homeostasis and cuproptosis by PDHA1 in acute myeloid leukemia.
Chen T, Wei N, Lv W, Qu L, Qu Q, Wu C, Ling Y, Liu H, Liu H
Discover oncology 2025 Jun 10;16(1):1044
Discover oncology 2025 Jun 10;16(1):1044
Role of thrombus-derived exosomal lncRNA LOC101928697 in regulating endothelial function via FUS protein interaction in myocardial infarction.
He Y, Liu W, Zhou Y, Ai L, Qian Y, Huang X, Peng L
Science progress 2025 Jul-Sep;108(3):368504251372111
Science progress 2025 Jul-Sep;108(3):368504251372111
Annexin A2: regulating glioma's fate and a potential therapeutic target.
Liu W, Zhao X, Regmi M, Shamsutdinova MI, Shamsutdinov M, Liu S, Dai Y, Wang Y, Liu H, Wu J, Yang J, Yang C, Sino-Uzbek Regenerative Therapy Consortium (SURE)
Medical oncology (Northwood, London, England) 2025 Jul 28;42(9):386
Medical oncology (Northwood, London, England) 2025 Jul 28;42(9):386
High glucose inhibits proliferation, migration, and osteogenic differentiation of human placenta-derived mesenchymal stem cells.
Duangprom S, Kheolamai P, Tantrawatpan C, Manochantr S
Scientific reports 2025 Jul 2;15(1):22512
Scientific reports 2025 Jul 2;15(1):22512
Elevated SGO2 expression in lung adenocarcinoma promotes migration and invasion via MAD2 and correlates with poor prognosis.
Sun M, Zhou W, Wei G, Lv M, Sun Y, Zhao H, Zhu C
Scientific reports 2025 Jul 15;15(1):25642
Scientific reports 2025 Jul 15;15(1):25642
Keratin 6A Overexpression in the Lymphovascular Invasion-Associated Tumor Subgroup Promotes Progression of Triple-Negative Breast Cancer.
Luo W, Zou Y, Jiang Y, Ma X, Guo S, Wang Y, Liu Y, Hai L, Jia W, Liu W, Meng R, Cao X, Ruan X, Yu Y
Cancer research and treatment 2025 Jul 14;
Cancer research and treatment 2025 Jul 14;
CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism.
Liu M, Gong Y, Cai H, Hua R, Li H, Wang Z, Zhou Y, Ma Y, Quan S
Journal of translational medicine 2025 Jul 10;23(1):763
Journal of translational medicine 2025 Jul 10;23(1):763
CircSMAD3 represses VSMC phenotype switching and neointima formation via promoting hnRNPA1 ubiquitination degradation.
Mei S, Ma X, Zhou L, Wuyun Q, Cai Z, Yan J, Ding H
Cell proliferation 2025 Jan;58(1):e13742
Cell proliferation 2025 Jan;58(1):e13742
Smurf2 Suppresses Proliferation and Cell Cycle of Triple-Negative Breast Cancer Cells by Promoting the Polyubiquitination and Degradation of RPL35A.
Wei S, Liu Y, Wang Z, Wei T, Zhou W, Li W, Zhang J, Liu Z, Liu Z
Journal of cellular and molecular medicine 2025 Jan;29(2):e70394
Journal of cellular and molecular medicine 2025 Jan;29(2):e70394
IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth.
Zhou B, Zhao Q, Hou G, He J, Sha N, Zheng K, Peng H, Wang W, Zhou Y, Chen T, Jiang Y
Cell reports 2025 Jan 28;44(1):115116
Cell reports 2025 Jan 28;44(1):115116
Delactylation diminished the growth inhibitory role of CA3 by restoring DUOX2 expression in hepatocellular carcinoma.
Yan J, Zhou Y, Xu J, Dong Y, Yang X, Yang X, Wu A, Chang S, Wang Y, Zhang Q, Ayaka T, Yu L, Zhao L, Meng H, Liu D
Experimental cell research 2025 Jan 15;444(2):114392
Experimental cell research 2025 Jan 15;444(2):114392
Environmental high temperature (heat stroke) causes articular cartilage damage in vivo and in vitro.
Yingfei S, Feng Y, Haoning M
Ecotoxicology and environmental safety 2025 Jan 15;290:117535
Ecotoxicology and environmental safety 2025 Jan 15;290:117535
Elevated SREBP1 accelerates the initiation and growth of pancreatic cancer by targeting SOX9.
Zhou C, Feng Z, Qian W, Zhu Z, Cao R, Wang Q, Zhang W, Liu R, Wu S, Hao J, Wang Z, Ma Q, Wu Z, Li X
Biology direct 2025 Jan 14;20(1):6
Biology direct 2025 Jan 14;20(1):6
miR-28-3p suppresses gastric cancer growth and EMT-driven metastasis by targeting the ARF6/Hedgehog axis.
Ji H, Liu S, Yang L, Wu Y, Zhang H, Liu X, Li L, Li L
Molecular and cellular probes 2025 Feb;79:102010
Molecular and cellular probes 2025 Feb;79:102010
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis.
Zhang Y, Zhu X, Chen L, Gao T, Chen G, Zhu J, Wang G, Zuo D
Neoplasia (New York, N.Y.) 2025 Feb;60:101096
Neoplasia (New York, N.Y.) 2025 Feb;60:101096
Organophosphate flame retardant triphenyl phosphate (TPhP) induced colonic fibrosis by bringing about epithelial-mesenchymal transition.
Peng C, Wang M, Zheng C, Zhang X, Chen Y, Wang L
Ecotoxicology and environmental safety 2025 Feb;291:117913
Ecotoxicology and environmental safety 2025 Feb;291:117913
Environmental high temperature induced cartilage damage through triggering programmed necrosis mediated by producing left-handed DNA.
Yingfei S, Feng Y, Haoning M
Ecotoxicology and environmental safety 2025 Feb;291:117894
Ecotoxicology and environmental safety 2025 Feb;291:117894
Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway.
Fan XP, Wang JR, Chen SY, Li XR, Cao JL, Wang HB, Ding LY, Che TJ, Yang L
Scientific reports 2025 Feb 8;15(1):4748
Scientific reports 2025 Feb 8;15(1):4748
PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53.
Fan Y, Li Y, Luo X, Xiang S, Hu J, Zhan J, Chang W, Deng R, Ran X, Zhang Y, Cai Y, Zhu W, Wang H, Liu Z, Wang D
Journal of translational medicine 2025 Feb 4;23(1):157
Journal of translational medicine 2025 Feb 4;23(1):157
Endothelial AGGF1 promotes retinal angiogenesis by coordinating TNFSF12/FN14 signalling.
Cheng Y, Zhang M, Li C, Su L, Fu L, Wu S, Xu C, Sun B, Chen L
Nature communications 2025 Feb 4;16(1):1332
Nature communications 2025 Feb 4;16(1):1332
Low expression of PRTN3 regulates the progression of gastric cancer by inhibition of cell cycle and promotion of apoptosis.
Zhu H, Wang F, Lu X, Wu H, Shi C, Matsas S, Peixoto RD, Aruquipa MPS, Tang C, Feng S
Translational cancer research 2025 Feb 28;14(2):1415-1427
Translational cancer research 2025 Feb 28;14(2):1415-1427
Thermoradiotherapy reverses proliferation, metastasis, and anoikis resistance in glioblastoma through ITGA5-PI3K/AKT axis.
Shi Y, An H, Wang W, Nan D, Cui Y, He M, Lian J, Zhang X, Peng J, Yang X, Liu P
Translational oncology 2025 Dec;62:102552
Translational oncology 2025 Dec;62:102552
WGCNA-identified COL13A1 drives osteosarcoma metastasis and progression via TGF-β signaling.
Xiao KW, Chen Z, Zhang C, Yang Z, Guo L, Xie Y, Lei J, Cai L
Journal of bone oncology 2025 Dec;55:100721
Journal of bone oncology 2025 Dec;55:100721
Bavachinin exerts anti-tumor effects by activating TLR4/STING axis-dependent PANoptosis and synergistically enhances chemosensitivity in endometrial cancer.
Shu W, Chen G, Zhang J, Dong K, Zhou T, Cheng S, Zhang T, Zhang J, Li H, Yao Y, Yu S, Liu Y, Zhou X, Shen X, Wang H
Biochemical pharmacology 2025 Dec;242(Pt 2):117321
Biochemical pharmacology 2025 Dec;242(Pt 2):117321
Targeting TRAF6 inhibits cystogenesis in autosomal dominant polycystic kidney disease.
Ren Y, Pan Y, Zhu X, Li L, Zhao W, Fu K, Chen Y, Sun Y, Guo D
Biochemical pharmacology 2025 Dec;242(Pt 2):117222
Biochemical pharmacology 2025 Dec;242(Pt 2):117222
Influence of coated cobalamin on lactation performance, nutrient digestion, and proteins related to mammary epithelial cell proliferation and milk fatty acid synthesis in dairy cows.
Zhang J, Lang J, Xue C, Liu Q, Pei C
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Dec;23:329-340
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Dec;23:329-340
Evaluation of anti-tumor activity of borated camptothecin derivatives targeting topoisomerase 1 against hepatocellular carcinoma and intrahepatic cholangiocarcinoma.
Zhang M, Xiang Y, Li C, Xu C, Chen G, Long R, Chen C, Liu Y, Ye F
Bioorganic chemistry 2025 Dec;167:109186
Bioorganic chemistry 2025 Dec;167:109186
Elevated SNHG15 empowers keratinocytes hyperproliferation through activation of STAT3/Cyclin D1 axis in psoriasis.
Tang L, Li G, Chang J, Xian H, Liu Y, Lin L, Dai Z, Liu Z, Qiu X, Zhang B, Su Z, Feng B, Zhu Y, Wang M, Chen Y, Liu H, Wu D, Li C, Zhao J, Li M, Zhu Y, Xie X, Deng H, Ye S, Fan S, Bi H, Lu C, Zheng G
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6430-6443
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6430-6443
Albiflorin enhances the antitumor effects of propofol in hepatocellular carcinoma cells by inhibiting the Wnt/β-catenin signaling activation.
Ji T, Ye L, Xu C, Ma C, Yin G
Translational cancer research 2025 Dec 31;14(12):8875-8888
Translational cancer research 2025 Dec 31;14(12):8875-8888
TRIM47-facilitated PLK1 stabilization promotes the proliferation of liver cancer cells.
Xie T, Fan X, Yu T, Zhu Q, Zhang Q, Li N, Wang T, Qian Y, Deng K, Xin H, Li Y, Huang X
Cellular oncology (Dordrecht, Netherlands) 2025 Dec 29;49(1):7
Cellular oncology (Dordrecht, Netherlands) 2025 Dec 29;49(1):7
Depleting CBR1 increases chemosensitivity by reducing stemness and quiescence traits in non-small cell lung cancer.
Li W, Zhao J, Lan W, Ye X, Ying K
Journal of Zhejiang University. Science. B 2025 Dec 17;26(12):1216-1232
Journal of Zhejiang University. Science. B 2025 Dec 17;26(12):1216-1232
Integrated multi-omics analysis revealed that SMARCAL1 serves as an immune related prognostic marker and promotes liver cancer growth via the Hippo/YAP signaling axis.
Huang T, Tang M, Tang Q, Di Y, Wang J, Duan Y, Zhang C, Bi F
International journal of surgery (London, England) 2025 Dec 17;112(4):10192-205
International journal of surgery (London, England) 2025 Dec 17;112(4):10192-205
THOC1 binds to U2AF2 and regulates ovarian cancer progression through the beta-catenin / c-myc / cyclinD1 signaling pathway.
Feng Y, Liu J, Zhang S, Zhang Z, Zhang D, Cao Y, Li M
Cancer cell international 2025 Dec 11;26(1):17
Cancer cell international 2025 Dec 11;26(1):17
ZEB1 Contributes to Drug Resistance Through Canonical Wnt Signaling in Lung Cancer.
Shi H, Wang M, Zhao Q, Xu Y
IUBMB life 2025 Aug;77(8):e70053
IUBMB life 2025 Aug;77(8):e70053
Application of PVA hydrogel loaded with luteolin nanoparticles in anti EMT treatment after GBM.
Zhou L, Zhao Q, Gu L, Tian R, Li Y, Xiong X
Materials today. Bio 2025 Aug;33:101956
Materials today. Bio 2025 Aug;33:101956
Decellularized human amniotic member hydrogel promotes limbal stem cells proliferation.
Tan Y, Wang W, Xu L, Zhou X, Shen J, Zhou T, Duan C, Wang X, Liu Z, Wang M, Li G
Colloids and surfaces. B, Biointerfaces 2025 Aug;252:114656
Colloids and surfaces. B, Biointerfaces 2025 Aug;252:114656
LIMK1 as a Novel Kinase of β-Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5.
Li SJ, Liang ZR, Liu ZC, Luo XP, Li JY, Yu XM, Huang XZ, He Y, Xu TY, Xu JJ, Peng SC, Song YX, He Y, Zhuang XW, Zheng CC, Zhang F, Lam AK, Dai W, He ML, Liu B, Zhao Q, Lu GL, Liu JB, Wang ZN, Li ZG, Liu ZX, Xu WW, Li B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e03223
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e03223
Folic acid-functionalized PLGA nanomedicines encapsulating echinacoside for liver cancer therapy.
Han Y, Fan J, Xia W, Dong X, Ye Y
Biochemical and biophysical research communications 2025 Aug 8;774:152049
Biochemical and biophysical research communications 2025 Aug 8;774:152049
WEE1 inhibitor exerts synergistic effect with KRAS G12C inhibitor via MYBL2-RRM2 axis in KRAS(G12C)-mutant lung cancer.
Zhou C, Liu Y, Liu H, Lu J, Zhang B, Zhu L, Wang S, Lei H, Han B
Cell death & disease 2025 Aug 30;16(1):661
Cell death & disease 2025 Aug 30;16(1):661
Paris saponin VII restrains PD-L1 mediated immune evasion through the AKT1 and STAT3 signaling pathways.
Wang Y, Li Y, Zhang Y, Li Y, Zhao L, Tong L, Zhu X, Wang J, Dong Y
Chemico-biological interactions 2025 Aug 25;417:111562
Chemico-biological interactions 2025 Aug 25;417:111562
RNA-binding motif protein RBM39 enhances the proliferation of gastric cancer cells by facilitating an oncogenic splicing switch in MRPL33.
Lu CP, Li JB, Li DB, Wang YH, Jiang XG, Ma JJ, Xu G
Acta pharmacologica Sinica 2025 Apr;46(4):1068-1081
Acta pharmacologica Sinica 2025 Apr;46(4):1068-1081
ELK4 induced upregulation of HOMER3 promotes the proliferation and metastasis in glioma via Wnt/β-catenin/EMT signaling pathway.
Wang F, Zhou H, Tian Y, Wang X, Huang Y, Tu Y, Li L, Zhen H
Biology direct 2025 Apr 9;20(1):48
Biology direct 2025 Apr 9;20(1):48
KIF14 plays a role in the regulation of the cell cycle and has implications for prognosis in clear cell renal cell carcinoma.
Wang J, Lai X, Sun Z, Feng S, Li B, Zhao H
BMC urology 2025 Apr 4;25(1):74
BMC urology 2025 Apr 4;25(1):74
A comprehensive analysis of deubiquitinase USP20 on prognosis and immunity in pan-cancer.
Wang T, Bai Y, Dong Y, Qin J, Zhou X, Wang A, Liu D, Li X, Ma Z, Hu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70499
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70499
Comprehensive analysis illustrating the role of HOXB8 in head and neck squamous cell carcinoma: evidence from multi-omics analysis and experiments validation.
Zhang JW, Gao XL, Wang J, Fan XL, Liang QW
BMC cancer 2025 Apr 30;25(1):804
BMC cancer 2025 Apr 30;25(1):804
F-box protein FBXO32 ubiquitinates and stabilizes D-type cyclins to drive cancer progression.
Li F, Yu H, Zhang Y, Ma Y, Chen X, Zhang J, Sun L, Guo R, Wu Y, Zheng P, Wang X, Bie P, He F, Zhang L, Xie C, Xiong H
Nature communications 2025 Apr 30;16(1):4060
Nature communications 2025 Apr 30;16(1):4060
SAP30 promotes clear cell renal cell carcinoma proliferation and inhibits apoptosis through the MT1G axis.
Guo W, Wang S, Yang Z, Dong Y, Xia Z, Xue W, Zhang C
European journal of medical research 2025 Apr 18;30(1):306
European journal of medical research 2025 Apr 18;30(1):306
CYR61 Acts as an Intracellular Microtubule-Associated Protein and Coordinates Mitotic Progression via PLK1-FBW7 Pathway.
Hu K, Xie L, Wu W, Zhang J, Li Y, He J, Zhang Y, Lu D, Koeffler HP, Lin L, Yin D
International journal of biological sciences 2024;20(8):3140-3155
International journal of biological sciences 2024;20(8):3140-3155
Cross-border regulation of the STK39/MAPK14 pathway by Lycium barbarum miR166a to inhibit triple-negative breast cancer.
Hou Y, Li J, Li X, Lv Y, Yuan C, Tian J, Liu X
American journal of translational research 2024;16(6):2683-2698
American journal of translational research 2024;16(6):2683-2698
CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis.
Zhang P, Yang Q, Chen X, Chen X, Wang Q, Chen K, An Y, Jiang K, Sun F
Journal of Cancer 2024;15(3):858-870
Journal of Cancer 2024;15(3):858-870
Apolipoprotein L3 inhibits breast cancer proliferation and modulates cell cycle via the P53 pathway.
Yu H, Li S, Li X, Liu Y, Wang Z, Cui M, Jin F, Yu X
Journal of Cancer 2024;15(14):4623-4635
Journal of Cancer 2024;15(14):4623-4635
GRB7-mediated enhancement of cell malignant characteristics induced by Helicobacter pylori infection.
Zhao H, Chen S, Bai X, Zhang J, Liu S, Sun Z, Cao X, Wang J, Zhang Y, Li B, Ji X
Frontiers in microbiology 2024;15:1469953
Frontiers in microbiology 2024;15:1469953
YTHDC1 Regulates the Migration, Invasion, Proliferation, and Apoptosis of Rheumatoid Fibroblast-Like Synoviocytes.
Feng ZW, Yang CF, Xiao HF, Yuan F, Chen F, Zhang B, Zhang J, Tan M, Guo MG
Frontiers in immunology 2024;15:1440398
Frontiers in immunology 2024;15:1440398
High glucose-induced NCAPD2 upregulation promotes malignant phenotypes and regulates EMT via the Wnt/β-catenin signaling pathway in HCC.
Mai Y, Liao C, Wang S, Zhou X, Meng L, Chen C, Qin Y, Deng G
American journal of cancer research 2024;14(4):1685-1711
American journal of cancer research 2024;14(4):1685-1711
Brucine Suppresses Malignant Progression of Prostate Cancer by Decreasing Sarcosine Accumulation via Downregulation of GNMT in the Glycine/sarcosine Metabolic Pathway.
Miao L, Liu Y, Chen W, Gao C, Zhang Y, Wei J, Cao X
Cell biochemistry and biophysics 2024 Sep;82(3):2373-2385
Cell biochemistry and biophysics 2024 Sep;82(3):2373-2385
Mechanistic elucidation of QiJu-DiHuang Wan in management of age-related dry eye through metabolomics and network pharmacology.
Shi J, Fang C, Liu Q, Chen X, Chen H, Tian S, Peng Q, Yao X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155884
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155884
Integrative analysis of the transcriptome and metabolome reveals the importance of hepatokine FGF21 in liver aging.
Wang W, Qian J, Shang M, Qiao Y, Huang J, Gao X, Ye Z, Tong X, Xu K, Li X, Liu Z, Zhou L, Zheng S
Genes & diseases 2024 Sep;11(5):101161
Genes & diseases 2024 Sep;11(5):101161
DCAF7 Acts as A Scaffold to Recruit USP10 for G3BP1 Deubiquitylation and Facilitates Chemoresistance and Metastasis in Nasopharyngeal Carcinoma.
Li QJ, Fang XL, Li YQ, Lin JY, Huang CL, He SW, Huang SY, Li JY, Gong S, Liu N, Ma J, Zhao Y, Tang LL
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2403262
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2403262
Tudor-SN exacerbates pathological vascular remodeling by promoting the polyubiquitination of PTEN via NEDD4-1.
Wu Y, Chen Z, Zheng Z, Li X, Shu J, Mao R, An J, Fan S, Luo R, Guo Y, Xu W, Liang M, Huang K, Wang C
Journal of biomedical science 2024 Sep 5;31(1):88
Journal of biomedical science 2024 Sep 5;31(1):88
KIFC3 promotes the proliferation, migration and invasion of non-small cell lung cancer through the PI3K/AKT signaling pathway.
Ma Y, Zhang Y, Jiang X, Guan J, Wang H, Zhang J, Tong Y, Qiu X, Zhou R
Scientific reports 2024 Sep 3;14(1):20471
Scientific reports 2024 Sep 3;14(1):20471
ARMCX1 inhibits lung adenocarcinoma progression by recruiting FBXW7 for c-Myc degradation.
Hu Z, Wu Y, Sun X, Tong Y, Qiu H, Zhuo E
Biology direct 2024 Sep 16;19(1):82
Biology direct 2024 Sep 16;19(1):82
Avermectin B1 mediates antitumor activity and induces autophagy in osteosarcoma through the AMPK/ULK1 signaling pathway.
Fei X, Li Z, Pan Z, Liang Y, Tan C, Cheng D, Yang Q
Cancer chemotherapy and pharmacology 2024 Oct;94(4):599-613
Cancer chemotherapy and pharmacology 2024 Oct;94(4):599-613
Xylooligosaccharides alleviate the carbohydrate-enriched diet-induced intestinal barrier dysfunction in carp Megalobrama amblycephala by promoting intestinal development, immunity and gut microbiota.
Chen WL, Dong YZ, Zhang L, Liu ZS, He CF, Liu WB, Li XF
International journal of biological macromolecules 2024 Oct;277(Pt 2):134346
International journal of biological macromolecules 2024 Oct;277(Pt 2):134346
Investigation on the mechanism of androsta-4,6,8,14-tetraene-3,11,16-trione against acute lymphoblastic leukemia.
Chen D, Wang Y, Xiao S, Cheng G, Liu Y, Zhao T, Cao J, Wen Y
The Journal of steroid biochemistry and molecular biology 2024 Oct;243:106573
The Journal of steroid biochemistry and molecular biology 2024 Oct;243:106573
Identification and biological evaluation of fused tetrahydroisoquinoline derivatives as Wnt/β-catenin signaling inhibitors to suppress colorectal cancer.
Zhou J, Xu B, Shen Q, Zhang Z, Hu Y, Wang M, Su Y, Lei Z, Zhang W, Liu T, Liu H, Hu T, Zhou Y
European journal of medicinal chemistry 2024 Oct 5;276:116664
European journal of medicinal chemistry 2024 Oct 5;276:116664
Elevated RBP4 in Subclinical Ketosis Cows Inhibits Follicular Granulosa Cell Proliferation and Steroid Hormone Synthesis.
Zhao C, Xu R, Yan W, Jiang B, Feng S, Wang X, Ding H
Animals : an open access journal from MDPI 2024 Oct 29;14(21)
Animals : an open access journal from MDPI 2024 Oct 29;14(21)
Glycyrrhizin ameliorates colorectal cancer progression by regulating NHEJ pathway through inhibiting HMGB1-induced DNA damage response.
Han Y, Sheng W, Liu X, Liu H, Jia X, Li H, Wang C, Wang B, Hu T, Ma Y
Scientific reports 2024 Oct 23;14(1):24948
Scientific reports 2024 Oct 23;14(1):24948
Discovery of Potent Covalent CRM1 Inhibitors Via a Customized Structure-Based Virtual Screening Pipeline and Bioassays.
Liu H, Shen C, Li H, Hou T, Yang Y
Journal of chemical information and modeling 2024 Oct 14;64(19):7422-7431
Journal of chemical information and modeling 2024 Oct 14;64(19):7422-7431
FAM83D promotes the progression of 4NQO-induced esophageal carcinoma via inhibiting FBWX7.
Li J, Tian J, Ma M, Qin Z, Cao B, Yang J, Wang X, Yang X
Experimental cell research 2024 Oct 1;442(2):114252
Experimental cell research 2024 Oct 1;442(2):114252
NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.
Yun F, Wu N, Yi X, Zhang X, Feng Y, Ni Q, Gai Y, Li E, Yang Z, Zhang Q, Sai B, Kuang Y, Zhu Y
Cell death & disease 2024 Oct 1;15(10):720
Cell death & disease 2024 Oct 1;15(10):720
DEAD/H-box helicase 11 is transcriptionally activated by Yin Yang-1 and accelerates oral squamous cell carcinoma progression.
Yang G, Shi X, Zhang M, Wang K, Tian X, Wang X
Cell biology international 2024 Nov;48(11):1731-1742
Cell biology international 2024 Nov;48(11):1731-1742
CircZMYM2 plays a pivotal role in osteosarcoma by regulating the translation of NACA and ARPC1B.
Li F, Wei J, Ren X, Hao Y, Tian S, Li L
Heliyon 2024 Nov 30;10(22):e37744
Heliyon 2024 Nov 30;10(22):e37744
Inhibition of the E3 ligase UBR5 stabilizes TERT and protects vascular organoids from oxidative stress.
Zhao H, Cao N, Liu Q, Zhang Y, Jin R, Lai H, Zheng L, Zhang H, Zhu Y, Ma Y, Yang Z, Wu Z, Li W, Liu Y, Cheng L, Chen Y
Journal of translational medicine 2024 Nov 28;22(1):1080
Journal of translational medicine 2024 Nov 28;22(1):1080
Enhancing radiosensitivity in osteosarcoma via CDKN2C overexpression: A mechanism involving G1 phase arrest mediated by inhibition of CDK4 expression and Thr172 phosphorylation.
Lian Q, Zhao H, Wang B, Ling P, Li J, Dai P, Ge J, Su X, Wang Z, Qiao S
Biochemical and biophysical research communications 2024 Nov 26;735:150840
Biochemical and biophysical research communications 2024 Nov 26;735:150840
P4HB maintains Wnt-dependent stemness in glioblastoma stem cells as a precision therapeutic target and serum marker.
Yuan Z, Jing H, Deng Y, Liu M, Jiang T, Jin X, Lin W, Liu Y, Yin J
Oncogenesis 2024 Nov 23;13(1):42
Oncogenesis 2024 Nov 23;13(1):42
GOS enhances BDNF-mediated mammary gland development in pubertal mice via the gut-brain axis.
Ge Y, Cao Y, Zhang J, Li F, Wang J, Sun M, Liu Y, Long X, Guo W, Liu J, Fu S
NPJ biofilms and microbiomes 2024 Nov 19;10(1):130
NPJ biofilms and microbiomes 2024 Nov 19;10(1):130
Hypoxia Stimulates PYGB Enzymatic Activity to Promote Glycogen Metabolism and Cholangiocarcinoma Progression.
Pan Y, Zhou Y, Shen Y, Xu L, Liu H, Zhang N, Huang T, Meng K, Liu Y, Wang L, Bai G, Chen Q, Zhu Y, Zou X, Wang S, Wang Z, Wang L
Cancer research 2024 Nov 15;84(22):3803-3817
Cancer research 2024 Nov 15;84(22):3803-3817
TBBPA exposure causes cartilage cell damage in both in vitro and in vivo models.
Yin B, Liu C, Sun H, Zhang W
Ecotoxicology and environmental safety 2024 Nov 15;287:117271
Ecotoxicology and environmental safety 2024 Nov 15;287:117271
SPIN1 accelerates tumorigenesis and confers radioresistance in non-small cell lung cancer by orchestrating the FOXO3a/FOXM1 axis.
Zhong M, Fang Z, Zou J, Chen X, Qiu Z, Zhou L, Le Y, Chen Z, Liao Y, Nie F, Wei X, Zhan J, Xiong J, Xiang X, Fang Z
Cell death & disease 2024 Nov 15;15(11):832
Cell death & disease 2024 Nov 15;15(11):832
Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells.
Wu Q, Chen M, Lin Y, Zhang J, Gao X, Wu Y, Wu C, Wen J, Li J, Li C, Bao W, Zhang D, Zheng M, Zhu A
Heliyon 2024 Nov 15;10(21):e38650
Heliyon 2024 Nov 15;10(21):e38650
Disulfiram Upgrades the Radiosensitivity of Osteosarcoma by Enhancing Apoptosis and P53-Induced Cell Cycle Arrest.
Lian Q, Chen F, Sha Z, Zhao H, Li J, Chen T, Liu C, Wang B, Wang Z, Qiao S
Radiation research 2024 Nov 1;202(5):752-764
Radiation research 2024 Nov 1;202(5):752-764
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
Huang Q, Chu Z, Wang Z, Li Q, Meng S, Lu Y, Ma K, Cui S, Hu W, Zhang W, Wei Q, Qu Y, Li H, Fu X, Zhang C
Nature communications 2024 May 9;15(1):3904
Nature communications 2024 May 9;15(1):3904
Integrating Epigenetics, Proteomics, and Metabolomics to Reveal the Involvement of Wnt/β-Catenin Signaling Pathway in Oridonin-Induced Reproductive Toxicity.
Wu Q, Gao X, Lin Y, Wu C, Zhang J, Chen M, Wen J, Wu Y, Tian K, Bao W, Sun P, Zhu A
Toxics 2024 May 7;12(5)
Toxics 2024 May 7;12(5)
Circ_0001671 regulates prostate cancer progression through miR-27b-3p/BLM axis.
Yang L, Ruan Y, Chen B, Zhu Y, Xu H
Scientific reports 2024 May 28;14(1):12181
Scientific reports 2024 May 28;14(1):12181
Antitumour effects of artesunate via cell cycle checkpoint controls in human oesophageal squamous carcinoma cells.
Mao L, Deng G, Li M, Lu SH, Jiang W, Yu X
European journal of medical research 2024 May 22;29(1):293
European journal of medical research 2024 May 22;29(1):293
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.
Zhang Q, Li Y, Zhu Q, Xie T, Xiao Y, Zhang F, Li N, Deng K, Xin H, Huang X
Cell death & disease 2024 May 22;15(5):355
Cell death & disease 2024 May 22;15(5):355
IDH1 mutation produces R-2-hydroxyglutarate (R-2HG) and induces mir-182-5p expression to regulate cell cycle and tumor formation in glioma.
Zhao H, Meng L, Du P, Liao X, Mo X, Gong M, Chen J, Liao Y
Biological research 2024 May 17;57(1):30
Biological research 2024 May 17;57(1):30
Curdepsidone A Induces Intrinsic Apoptosis and Inhibits Protective Autophagy via the ROS/PI3K/AKT Signaling Pathway in HeLa Cells.
Xu S, Li Z, Xin X, An F
Marine drugs 2024 May 17;22(5)
Marine drugs 2024 May 17;22(5)
Combined SET7/9 and CDK4 inhibition act synergistically against osteosarcoma.
Shi Y, Wang Z, Shao Y, Guang Q, Zhang J, Liu B, Wu C, Wang Y, Sui P
Biochemical and biophysical research communications 2024 May 14;708:149808
Biochemical and biophysical research communications 2024 May 14;708:149808
Copper Chaperone Atox1 Protected the Cochlea From Cisplatin by Regulating the Copper Transport Family and Cell Cycle.
Chen X, Xiang W, Li L, Xu K
International journal of toxicology 2024 Mar-Apr;43(2):134-145
International journal of toxicology 2024 Mar-Apr;43(2):134-145
Cynaroside Induces G1 Cell Cycle Arrest by Downregulating Cell Division Cycle 25A in Colorectal Cancer.
Lei S, Cao W, Zeng Z, Wang L, Lan J, Chen T
Molecules (Basel, Switzerland) 2024 Mar 28;29(7)
Molecules (Basel, Switzerland) 2024 Mar 28;29(7)
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
Fei X, Zhu C, Liu P, Liu S, Ren L, Lu R, Hou J, Gao Y, Wang X, Pan Y
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
ART1 knockdown decreases the IL-6-induced proliferation of colorectal cancer cells.
Lin T, Zhang S, Tang Y, Xiao M, Li M, Gong H, Xie H, Wang Y
BMC cancer 2024 Mar 19;24(1):354
BMC cancer 2024 Mar 19;24(1):354
YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia.
Liu Z, Li S, Chen S, Sheng J, Li Z, Lv T, Yu W, Fan Y, Wang J, Liu W, Hu S, Jin J
iScience 2024 Mar 15;27(3):109125
iScience 2024 Mar 15;27(3):109125
CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8 + T cell response.
Cen Q, Chen J, Guo J, Chen M, Wang H, Wu S, Zhang H, Xie X, Li Y
Journal of translational medicine 2024 Mar 14;22(1):278
Journal of translational medicine 2024 Mar 14;22(1):278
β-catenin/TCF4-induced SCUBE3 upregulation promotes ovarian cancer development via HIF-1 signaling pathway.
Shen J, Ma X, Wei Z, Qian Q, Jing A, Ding Y, Geng T, Qin J, Ma L, Chen Y, Ji J, Liu B, Huang J
Molecular and cellular endocrinology 2024 Mar 1;582:112127
Molecular and cellular endocrinology 2024 Mar 1;582:112127
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
Guo Y, Feng Y, Jiang F, Hu L, Shan T, Li H, Liao H, Bao H, Shi H, Si Y
Brain research 2024 Mar 1;1826:148731
Brain research 2024 Mar 1;1826:148731
ZNF862 induces cytostasis and apoptosis via the p21-RB1 and Bcl-xL-Caspase 3 signaling pathways in human gingival fibroblasts.
Zhu Y, Zhao T, Wu Y, Xie S, Sun W, Wu J
Journal of periodontal research 2024 Jun;59(3):599-610
Journal of periodontal research 2024 Jun;59(3):599-610
Bioinspired engineering ADSC nanovesicles thermosensitive hydrogel enhance autophagy of dermal papilla cells for androgenetic alopecia treatment.
Xiong J, Liu Z, Jia L, Sun Y, Guo R, Xi T, Li Z, Wu M, Jiang H, Li Y
Bioactive materials 2024 Jun;36:112-125
Bioactive materials 2024 Jun;36:112-125
AS1411 binds to nucleolin via its parallel structure and disrupts the exos-miRNA-27a-mediated reciprocal activation loop between glioma and astrocytes.
Sun X, Zhang W, Gou C, Wang X, Wang X, Shao X, Chen X, Chen Z
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167211
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167211
Teriflunomide/leflunomide synergize with chemotherapeutics by decreasing mitochondrial fragmentation via DRP1 in SCLC.
Mirzapoiazova T, Tseng L, Mambetsariev B, Li H, Lou CH, Pozhitkov A, Ramisetty SK, Nam S, Mambetsariev I, Armstrong B, Malhotra J, Arvanitis L, Nasser MW, Batra SK, Rosen ST, Wheeler DL, Singhal SS, Kulkarni P, Salgia R
iScience 2024 Jun 21;27(6):110132
iScience 2024 Jun 21;27(6):110132
Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinoma.
Zhang R, Dai J, Yao F, Zhou S, Huang W, Xu J, Yu K, Chen Y, Fan B, Zhang L, Xu J, Li Q
iScience 2024 Jun 21;27(6):109821
iScience 2024 Jun 21;27(6):109821
Potential Molecular Mechanism of Illicium simonsii Maxim Petroleum Ether Fraction in the Treatment of Hepatocellular Carcinoma.
Zou S, Wu Y, Wen M, Liu J, Chen M, Yuan J, Zhou B
Pharmaceuticals (Basel, Switzerland) 2024 Jun 19;17(6)
Pharmaceuticals (Basel, Switzerland) 2024 Jun 19;17(6)
Design, synthesis and biological evaluation of indoline-maleimide conjugates as potential antitumor agents for the treatment of colorectal cancer.
Tang J, Zhang Y, Zhou L, Song X, Wei Y, Qi J, Wu J, Song Z, Zhan L
Bioorganic & medicinal chemistry 2024 Jun 15;108:117786
Bioorganic & medicinal chemistry 2024 Jun 15;108:117786
Naringenin enhances the efficacy of ferroptosis inducers by attenuating aerobic glycolysis by activating the AMPK-PGC1α signalling axis in liver cancer.
Li YZ, Deng J, Zhang XD, Li DY, Su LX, Li S, Pan JM, Lu L, Ya JQ, Yang N, Zhou J, Yang LH
Heliyon 2024 Jun 15;10(11):e32288
Heliyon 2024 Jun 15;10(11):e32288
ANGPTL3 diminishes the resistance of ovarian cancer to paclitaxel by blocking the PI3K-AKT-mTOR signaling pathway.
Wu D, Liu J, Yang X, Wu Z, Wang T, Xiao M
Heliyon 2024 Jun 15;10(11):e31520
Heliyon 2024 Jun 15;10(11):e31520
Overexpression of FHL1 suppresses papillary thyroid cancer proliferation and progression via inhibiting Wnt/β-catenin pathway.
Chen J, Zeng C, Jin J, Zhang P, Zhang Y, Zhang H, Li Y, Guan H
Endocrine 2024 Jul;85(1):238-249
Endocrine 2024 Jul;85(1):238-249
Melatonin promotes cell cycle progression of neural stem cells subjected to manganese via Nurr1.
Chen N, Zhou H, He B, Peng S, Ding F, Liu QH, Ma Z, Liu W, Xu B
Environmental toxicology 2024 Jul;39(7):3883-3896
Environmental toxicology 2024 Jul;39(7):3883-3896
Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells.
Song Y, Deng M, Qiu Y, Cui Y, Zhang B, Xin J, Feng L, Mu X, Cui J, Li H, Sun Y, Yi W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155592
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155592
HNF4α improves hepatocyte regeneration by upregulating PXR.
Qiu S, Pan Y, Cui Y, Li M, Yue T, Pu S, Zhang Q, Wang M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23830
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23830
SPP1 could be an immunological and prognostic biomarker: From pan-cancer comprehensive analysis to osteosarcoma validation.
Zhang Z, Liu B, Lin Z, Mei L, Chen R, Li Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23783
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23783
Exploring the key genes associated with breast cancer radiotherapy sensitivity based on the stromal-immune score and analysis of the WGCNA and ceRNA network.
Sun X, Wu C, Lin Y, Zhang S, Zhao X, Wang X
Heliyon 2024 Jul 30;10(14):e34630
Heliyon 2024 Jul 30;10(14):e34630
Screening and identification of miRNAs negatively regulating FAM83A/Wnt/β-catenin signaling pathway in non-small cell lung cancer.
Yuan W, Liu W, Huang H, Chen X, Zhang R, Lyu H, Xiao S, Guo D, Zhang Q, Ali DW, Michalak M, Chen XZ, Zhou C, Tang J
Scientific reports 2024 Jul 29;14(1):17394
Scientific reports 2024 Jul 29;14(1):17394
Inhibition of DNA Topoisomerase Ι by Flavonoids and Polyacetylenes Isolated from Bidens pilosa L.
Zeng G, Wang Y, Zhu M, Yi J, Ma J, Yang B, Sun W, Dai F, Yin J, Zeng G
Molecules (Basel, Switzerland) 2024 Jul 27;29(15)
Molecules (Basel, Switzerland) 2024 Jul 27;29(15)
miR-126a-5p inhibits H1N1-induced inflammation and matrix protease secretion in lung fibroblasts by targeting ADAMTS-4.
Fang F, Wang B, Lu X, Wang L, Chen X, Wang G, Yang Y
Archives of virology 2024 Jul 11;169(8):164
Archives of virology 2024 Jul 11;169(8):164
let-7g sensitized liver cancer cells to 5-fluorouracil by downregulating ABCC10 expression.
Chen Y, Zhang B, Zhong C, Zhou Y, Xue L, Luo C, Yi L, Gong Q, Long Y
Chemical biology & drug design 2024 Jan;103(1):e14396
Chemical biology & drug design 2024 Jan;103(1):e14396
MALAT1/miR-7-5p/TCF4 Axis Regulating Menstrual Blood Mesenchymal Stem Cells Improve Thin Endometrium Fertility by the Wnt Signaling Pathway.
Wang H, Chen K, Zong L, Zhao X, Wang J, Fan S, Shen B, Zheng S
Cell transplantation 2024 Jan-Dec;33:9636897241259552
Cell transplantation 2024 Jan-Dec;33:9636897241259552
TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma.
Chen Y, Han Z, Zhang L, Gao C, Wei J, Yang X, Han Y, Li Y, Zhang C, Wei Y, Dong J, Xun W, Sun W, Zhang T, Zhang H, Chen J, Yuan P
Journal of translational medicine 2024 Jan 4;22(1):21
Journal of translational medicine 2024 Jan 4;22(1):21
MiR-199a-5p inhibits dermal papilla cells proliferation by regulating VEGFA expression in cashmere goat.
Zhang T, Zheng Y, Zhang F, Wang X, Du J, Wang X
Gene 2024 Jan 30;893:147901
Gene 2024 Jan 30;893:147901
CHEK2 knockout is a therapeutic target for TP53-mutated hepatocellular carcinoma.
Chen Y, Zhu Z, Wu X, Li H, Guan W, Ren H
Cell death discovery 2024 Jan 19;10(1):37
Cell death discovery 2024 Jan 19;10(1):37
Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.
Shi M, Huang K, Wei J, Wang S, Yang W, Wang H, Li Y
International journal of molecular sciences 2024 Jan 14;25(2)
International journal of molecular sciences 2024 Jan 14;25(2)
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Zhan J, Zhou L, Zhang H, Zhou J, He Y, Hu T, Le Y, Lin Y, Wang J, Yu H, Liu Y, Xiang X
Translational oncology 2024 Feb;40:101843
Translational oncology 2024 Feb;40:101843
Cepharanthine suppresses APC-mutant colorectal cancers by down-regulating the expression of β-catenin.
Su G, Wang D, Yang Q, Kong L, Ju X, Yang Q, Zhu Y, Zhang S, Li Y
Natural products and bioprospecting 2024 Feb 29;14(1):18
Natural products and bioprospecting 2024 Feb 29;14(1):18
Schisandrin B promotes hepatic differentiation from human umbilical cord mesenchymal stem cells.
Jin M, Yi X, Zhu X, Hu W, Wang S, Chen Q, Yang W, Li Y, Li S, Peng Q, Pan M, Gao Y, Xu S, Zhang Y, Zhou S
iScience 2024 Feb 16;27(2):108912
iScience 2024 Feb 16;27(2):108912
ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner.
Zhang C, Yu Z, Yang S, Liu Y, Song J, Mao J, Li M, Zhao Y
Molecular cancer 2024 Feb 14;23(1):33
Molecular cancer 2024 Feb 14;23(1):33
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
Xu J, Wu X, Zhu H, Zhu Y, Du K, Deng X, Wang C
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
Pharmacological USP2 targeting suppresses ovarian cancer growth by potentiating apoptosis and ferroptosis.
Yang D, Liu X, Yang Y, Long Y, Nan D, Shi B, Wang J, Yang M, Cong H, Xing L, Zhou F, Yuan Q, Ta N, Zhang Y, Ma R, Liu F, Liu S
Archives of biochemistry and biophysics 2024 Dec;762:110193
Archives of biochemistry and biophysics 2024 Dec;762:110193
Knockdown of PIK3R6 impedes the onset and advancement of clear cell renal cell carcinoma.
Yang J, Zhong X, Gao X, Xie W, Chen Y, Liao Y, Zhang P
Cell adhesion & migration 2024 Dec;18(1):1-12
Cell adhesion & migration 2024 Dec;18(1):1-12
BMP5 promotes trophoblast functions upon N-glycosylation via the BMP5-SMAD1/5 signaling pathway in preeclampsia.
Wang H, Fan N, Cui X, Xie R, Tang Y, Thomas AM, Li S, Zhang JV, Liu S, Qin H
Placenta 2024 Dec;158:240-252
Placenta 2024 Dec;158:240-252
MEK inhibitor trametinib combined with PI3K/mTOR inhibitor BEZ-235 as an effective strategy against NSCLC through impairment of glucose metabolism.
Liu Y, Qing B, Ke W, Wang M
Cellular signalling 2024 Dec;124:111415
Cellular signalling 2024 Dec;124:111415
Pharmacological inhibition of SREBP1 suppresses pancreatic cancer growth via inducing GPX4-mediated ferroptosis.
Cao R, Feng Z, Mo J, Wu J, Li J, Li W, Wang Z, Ma Q, Wu Z, Zhou C
Cellular signalling 2024 Dec;124:111381
Cellular signalling 2024 Dec;124:111381
miR-548az-5p induces amniotic epithelial cell senescence by regulating KATNAL1 expression in labor.
Jing D, Liu Q, Zhang H, Li Y, Jiang X, Cai Y, Wang X, Li L
Scientific reports 2024 Dec 5;14(1):30380
Scientific reports 2024 Dec 5;14(1):30380
GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT3.
Chen Z, Xu L, Lin S, Huang H, Long Q, Liu J
Cancer biology & therapy 2024 Dec 31;25(1):2420383
Cancer biology & therapy 2024 Dec 31;25(1):2420383
F13B regulates angiogenesis and tumor progression in hepatocellular carcinoma via the HIF-1α/VEGF pathway.
Jiang D, Qi Z, Xu ZY, Li YR
Biomolecules & biomedicine 2024 Dec 11;25(1):189-209
Biomolecules & biomedicine 2024 Dec 11;25(1):189-209
Cyclosporine A Causes Gingival Overgrowth by Promoting Entry into the S Phase at the G1/S Cell Cycle Checkpoint in Gingival Fibroblasts Exposed to Lipopolysaccharide.
Takeuchi R, Kuwahara N, Amino Y, Hayashi S, Taguchi C, Suzuki I, Suzuki H, Nagashima T, Arikawa K, Okada Y, Nomoto T, Hiratsuka K
Diseases (Basel, Switzerland) 2024 Dec 10;12(12)
Diseases (Basel, Switzerland) 2024 Dec 10;12(12)
Enhancing therapeutic efficacy in homologous recombination-proficient pancreatic cancer via the combination of PARP1-PROTAC and a BRD4 inhibitor.
Pu C, Liu Y, Lan S, Fan H, Liu L, Liu J, Guo Y
Bioorganic & medicinal chemistry 2024 Dec 1;115:117970
Bioorganic & medicinal chemistry 2024 Dec 1;115:117970
Dendrobium nobile active ingredient Dendrobin A against hepatocellular carcinoma via inhibiting nuclear factor kappa-B signaling.
Yu Y, Fan Y, Mei W, Xu X, Chen Y, Zhao Y, Ruan B, Shen Z, Lu Y, Zheng S, Jie W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117013
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117013
Antitumorigenic potential of Lactobacillus-derived extracellular vesicles: p53 succinylation and glycolytic reprogramming in intestinal epithelial cells via SIRT5 modulation.
Zhang J, Huang X, Zhang T, Gu C, Zuo W, Fu L, Dong Y, Liu H
Cell biology and toxicology 2024 Aug 7;40(1):66
Cell biology and toxicology 2024 Aug 7;40(1):66
Identification of TAT as a Biomarker Involved in Cell Cycle and DNA Repair in Breast Cancer.
Xie F, Hua S, Guo Y, Wang T, Shan C, Zhang L, He T
Biomolecules 2024 Aug 30;14(9)
Biomolecules 2024 Aug 30;14(9)
MZT2A serves as a prognostic biomarker and promotes the progression of kidney renal clear cell carcinoma.
Cao L, Jing X, Liu L, Wang H, Zhu J, Zhou J, Peng H, Zhang J, Li F, Wang X, Zhao L
Heliyon 2024 Aug 15;10(15):e35695
Heliyon 2024 Aug 15;10(15):e35695
Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis.
Li T, Gao S, Wei Y, Wu G, Feng Y, Wang Y, Jiang X, Kuang H, Han W
Journal of pharmaceutical and biomedical analysis 2024 Aug 1;245:116163
Journal of pharmaceutical and biomedical analysis 2024 Aug 1;245:116163
Bufalin Suppresses Head and Neck Cancer Development by Modulating Immune Responses and Targeting the β-Catenin Signaling Pathway.
Mhaidly N, Barake N, Trelcat A, Journe F, Saussez S, Descamps G
Cancers 2024 Aug 1;16(15)
Cancers 2024 Aug 1;16(15)
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
Liu Z, Zhao P
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Wang P, Zhang H, Guo K, Liu C, Chen S, Pu B, Chen S, Feng T, Jiao H, Gao C
Oncology letters 2024 Apr;27(4):140
Oncology letters 2024 Apr;27(4):140
Matairesinoside, a novel inhibitor of TMEM16A ion channel, loaded with functional hydrogel for lung cancer treatment.
Wang Z, Geng R, Chen Y, Qin J, Guo S
International journal of biological macromolecules 2024 Apr;264(Pt 2):130618
International journal of biological macromolecules 2024 Apr;264(Pt 2):130618
TuBG1 promotes hepatocellular carcinoma via ATR/P53-apoptosis and cycling pathways.
Zhang Y, Wang ZZ, Han AQ, Yang MY, Zhu LX, Pan FM, Wang Y
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Apr;23(2):195-209
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Apr;23(2):195-209
Cadmium disrupts spermatogenic cell cycle via piRNA-DQ717867/p53 pathway.
Wei J, Dai J, Shi X, Zhao R, Fu G, Li R, Xia C, Zhang L, Zhou T, Wang H, Shi Y
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108554
Reproductive toxicology (Elmsford, N.Y.) 2024 Apr;125:108554
Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis.
Liu B, Xian Y, Chen X, Shi Y, Dong J, Yang L, An X, Shen T, Wu W, Ma Y, He Y, Gong W, Peng R, Lin J, Liu N, Guo B, Jiang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307338
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307338
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
RETRACTED: High PGC-1α Expression as a Poor Prognostic Indicator in Intracranial Glioma.
Cheng YW, Lee JH, Chang CH, Tseng TT, Chai CY, Lieu AS, Kwan AL
Biomedicines 2024 Apr 29;12(5)
Biomedicines 2024 Apr 29;12(5)
Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer.
Han JY, Che N, Mo J, Zhang DF, Liang XH, Dong XY, Zhao XL, Sun BC
BMC cancer 2024 Apr 26;24(1):532
BMC cancer 2024 Apr 26;24(1):532
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
Zhang M, Cai F, Guo J, Liu S, Ma G, Cai M, Zhang R, Deng J
Cell death & disease 2024 Apr 26;15(4):297
Cell death & disease 2024 Apr 26;15(4):297
Peptide Inhibitor Targeting the Extraterminal Domain in BRD4 Potently Suppresses Breast Cancer Both In Vitro and In Vivo.
Huang QX, Fan DM, Zheng ZZ, Ran T, Bai A, Xiao RQ, Hu GS, Liu W
Journal of medicinal chemistry 2024 Apr 25;67(8):6658-6672
Journal of medicinal chemistry 2024 Apr 25;67(8):6658-6672
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression.
Wu J, Wen T, Marzio A, Song D, Chen S, Yang C, Zhao F, Zhang B, Zhao G, Ferri A, Cheng H, Ma J, Ren H, Chen QY, Yang Y, Qin S
Cell death & disease 2024 Apr 20;15(4):282
Cell death & disease 2024 Apr 20;15(4):282
Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma.
Sun Y, Chen Y, Zhao H, Wang J, Liu Y, Bai J, Hu C, Shang Z
iScience 2024 Apr 19;27(4):109340
iScience 2024 Apr 19;27(4):109340
PRMT6-mediated transcriptional activation of ythdf2 promotes glioblastoma migration, invasion, and emt via the wnt-β-catenin pathway.
Yu P, Xu T, Ma W, Fang X, Bao Y, Xu C, Huang J, Sun Y, Li G
Journal of experimental & clinical cancer research : CR 2024 Apr 18;43(1):116
Journal of experimental & clinical cancer research : CR 2024 Apr 18;43(1):116
The role of miR-222-2p in exosomes secreted by hexavalent chromium-induced premature senescent hepatocytes as a SASP component.
Ma Y, Li S, Ye S, Luo S, Wei L, Su Y, Zeng Y, Shi Y, Bian H, Xiao F
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123535
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123535
Isolation and Cultivation of Vascular Smooth Muscle Cells from the Mouse Circle of Willis.
Chang W, Li Y, Liu F, Zang K, Zhang P, Qu S, Zhao J, Xue J
Journal of vascular research 2023;60(4):234-244
Journal of vascular research 2023;60(4):234-244
MKRN1/2 serve as tumor suppressors in renal clear cell carcinoma by regulating the expression of p53.
Yang Y, Luo Y, Huang S, Tao Y, Li C, Wang C
Cancer biomarkers : section A of Disease markers 2023;36(4):267-278
Cancer biomarkers : section A of Disease markers 2023;36(4):267-278
NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner.
Zhou Y, Qian W, Li X, Wei W
Oxidative medicine and cellular longevity 2023;2023:7098313
Oxidative medicine and cellular longevity 2023;2023:7098313
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Zhu Y, Sun W, Jiang X, Bai R, Luo Y, Gao Y, Li S, Huang Z, Gong Y, Xie C
PloS one 2023;18(1):e0281132
PloS one 2023;18(1):e0281132
The cancer/testis antigen HORMAD1 promotes gastric cancer progression by activating the NF-κB signaling pathway and inducing epithelial-mesenchymal transition.
Bian G, Li W, Huang D, Zhang Q, Ding X, Zang X, Ye Y, Cao J, Li P
American journal of translational research 2023;15(9):5808-5825
American journal of translational research 2023;15(9):5808-5825
PRMT7 Inhibits the Proliferation and Migration of Gastric Cancer Cells by Suppressing the PI3K/AKT Pathway via PTEN.
Wang X, Xu W, Zhu C, Cheng Y, Qi J
Journal of Cancer 2023;14(15):2833-2844
Journal of Cancer 2023;14(15):2833-2844
HSP105 suppresses the progression of cutaneous squamous cell carcinoma by activating the P53 signaling pathway.
Jia M, Zhou KY, Deng LJ, Fang S
American journal of cancer research 2023;13(7):3013-3026
American journal of cancer research 2023;13(7):3013-3026
Prognostic and therapeutic implications of iron-related cell death pathways in acute myeloid leukemia.
Li T, Lin T, Zhu J, Zhou M, Fan S, Zhou H, Mu Q, Sheng L, Ouyang G
Frontiers in oncology 2023;13:1222098
Frontiers in oncology 2023;13:1222098
Role of UDP-glucose ceramide glucosyltransferase in venous malformation.
Chen S, Wang Y, Kong L, Ji Y, Cui J, Shen W
Frontiers in cell and developmental biology 2023;11:1178045
Frontiers in cell and developmental biology 2023;11:1178045
LINC02870 facilitates SNAIL translation to promote hepatocellular carcinoma progression.
Guo M, Zhuang H, Huang J, Shao X, Bai N, Li M, Niu M, Wei W, Sun L, Li Y, Qiang Z
Molecular and cellular biochemistry 2023 Sep;478(9):1899-1914
Molecular and cellular biochemistry 2023 Sep;478(9):1899-1914
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression.
An X, Wu W, Yang L, Dong J, Liu B, Guo J, Chen J, Guo B, Cao W, Jiang Q
Translational research : the journal of laboratory and clinical medicine 2023 Sep;259:62-71
Translational research : the journal of laboratory and clinical medicine 2023 Sep;259:62-71
CCDC85C suppresses colorectal cancer cells proliferation and metastasis through activating GSK-3β and promoting β-catenin degradation.
Hu W, Shen J, Tao Y, Dong D, Lu S, Li L, Sun D, Fan M, Xu C, Shen W, Yu C, Cheng H
Cellular signalling 2023 Sep;109:110799
Cellular signalling 2023 Sep;109:110799
SUMO-Activating Enzyme Subunit 1 Is Associated with Poor Prognosis, Tumor Progression, and Radio-Resistance in Colorectal Cancer.
Wu YJ, Huang ST, Chang YH, Lin SY, Lin WL, Chen YJ, Chien ST
Current issues in molecular biology 2023 Sep 30;45(10):8013-8026
Current issues in molecular biology 2023 Sep 30;45(10):8013-8026
Ar-turmerone inhibits the proliferation and mobility of glioma by downregulating cathepsin B.
Cao W, Chen X, Xiao C, Lin D, Li Y, Luo S, Zeng Z, Sun B, Lei S
Aging 2023 Sep 26;15(18):9377-9390
Aging 2023 Sep 26;15(18):9377-9390
Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.
Guo Z, Guo L
Experimental cell research 2023 Sep 15;430(2):113714
Experimental cell research 2023 Sep 15;430(2):113714
DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.
Wen R, Zhou L, Jiang S, Fan H, Zheng K, Yu Y, Gao X, Hao L, Lou Z, Yu G, Yang F, Zhang W
International journal of radiation oncology, biology, physics 2023 Sep 1;117(1):198-210
International journal of radiation oncology, biology, physics 2023 Sep 1;117(1):198-210
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Wu Y, Chen W, Zhang B, Liu H
Tissue & cell 2023 Oct;84:102193
Tissue & cell 2023 Oct;84:102193
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
Yao X, Liu H, Wang Z, Lu F, Chen W, Feng Q, Miao Y, Zhang J, Wang Y, Chen Y, Xue L, Liu Y, Chen L, Zhang Q
Oncogene 2023 Oct;42(43):3206-3218
Oncogene 2023 Oct;42(43):3206-3218
MTHFD2 promotes PD-L1 expression via activation of the JAK/STAT signalling pathway in bladder cancer.
Li L, Zhang Y, Hu W, Zou F, Ning J, Rao T, Ruan Y, Yu W, Cheng F
Journal of cellular and molecular medicine 2023 Oct;27(19):2922-2936
Journal of cellular and molecular medicine 2023 Oct;27(19):2922-2936
Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.
Yin J, Hu T, Xu L, Zhang L, Zhu J, Ye Y, Pang Z
International immunopharmacology 2023 Oct;123:110763
International immunopharmacology 2023 Oct;123:110763
Role of Nucleobindin-2 in the Clinical Pathogenesis and Treatment Resistance of Glioblastoma.
Lin IC, Chang CH, Chong YB, Kuo SH, Cheng YW, Lieu AS, Tseng TT, Lin CJ, Tsai HP, Kwan AL
Cells 2023 Oct 9;12(19)
Cells 2023 Oct 9;12(19)
PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer.
Zhao S, Li Y, Li G, Ye J, Wang R, Zhang X, Li F, Gao C, Li J, Jiang J, Mi Y
European journal of pharmacology 2023 Oct 15;957:176004
European journal of pharmacology 2023 Oct 15;957:176004
A pan-cancer analysis of the role of HOXD1, HOXD3, and HOXD4 and validation in renal cell carcinoma.
Wang L, Wang X, Sun H, Wang W, Cao L
Aging 2023 Oct 12;15(19):10746-10766
Aging 2023 Oct 12;15(19):10746-10766
IGF2BP2 acts as a m(6)A modification regulator in laryngeal squamous cell carcinoma through facilitating CDK6 mRNA stabilization.
Tang X, Tang Q, Li S, Li M, Yang T
Cell death discovery 2023 Oct 10;9(1):371
Cell death discovery 2023 Oct 10;9(1):371
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice.
Jiang PY, Lin S, Liu JR, Liu Y, Zheng LM, Hong Q, Fan YJ, Xu DX, Chen YH
Archives of toxicology 2023 Nov;97(11):2929-2941
Archives of toxicology 2023 Nov;97(11):2929-2941
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Ma H, Jiang S, Yuan Y, Li J, Li Y, Lv Y, Du T, Guan J, Jiang X, Tian L, Zheng Q, Yang L, Li Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
IL-7 promotes CD19-directed CAR-T cells proliferation through miRNA-98-5p by targeting CDKN1A.
Yang LR, Li L, Meng MY, Li TT, Zhao YY, Yang SL, Gao H, Tang WW, Yang Y, Yang LL, Wang WJ, Liao LW, Hou ZL
International immunopharmacology 2023 Nov;124(Pt B):110974
International immunopharmacology 2023 Nov;124(Pt B):110974
A large-scale transcriptional analysis reveals herb-derived ginsenoside F2 suppressing hepatocellular carcinoma via inhibiting STAT3.
Tan X, Ma X, Dai Y, An J, Yu X, Li S, Liao Y, Pei T, Tang Y, Gui Y, Zhou S, Guo D, Deng Y, Hu K, Wang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155031
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155031
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
Zhang Y, Fan Y, Hu H, Zhang X, Wang Z, Wu Z, Wang L, Yu X, Song X, Xiang P, Zhang X, Wang T, Tan S, Li C, Gao L, Liang X, Li S, Li N, Yue X, Ma C
Nature communications 2023 Nov 18;14(1):7527
Nature communications 2023 Nov 18;14(1):7527
Tripartite motif 31 drives gastric cancer cell proliferation and invasion through activating the Wnt/β-catenin pathway by regulating Axin1 protein stability.
Feng Q, Nie F, Gan L, Wei X, Liu P, Liu H, Zhang K, Fang Z, Wang H, Fang N
Scientific reports 2023 Nov 16;13(1):20099
Scientific reports 2023 Nov 16;13(1):20099
GAD1-mediated GABA elicits aggressive characteristics of human oral cancer cells.
Dou Z, Li M, Shen Z, Jiang H, Pang X, Li T, Liang X, Tang Y
Biochemical and biophysical research communications 2023 Nov 12;681:80-89
Biochemical and biophysical research communications 2023 Nov 12;681:80-89
Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway.
Wang S, Zhang X, Lei H, Song L, Huang Y, Kang T, Zhang M, Wang N, Yang P, Feng S, Wang J, Bai R, Wang N, Wang W, Zheng Y
Molecular carcinogenesis 2023 May;62(5):613-627
Molecular carcinogenesis 2023 May;62(5):613-627
Targeting diacylglycerol kinase α impairs lung tumorigenesis by inhibiting cyclin D3.
Zhou D, Liu T, Rao X, Jie X, Chen Y, Wu Z, Deng H, Zhang D, Wang J, Wu G
Thoracic cancer 2023 May;14(13):1179-1191
Thoracic cancer 2023 May;14(13):1179-1191
The High Level of RANKL Improves IκB/p65/Cyclin D1 Expression and Decreases p-Stat5 Expression in Firm Udder of Dairy Goats.
Gao Z, Shao D, Zhao C, Liu H, Zhao X, Wei Q, Ma B
International journal of molecular sciences 2023 May 16;24(10)
International journal of molecular sciences 2023 May 16;24(10)
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Li Z, Chen C, Yong H, Jiang L, Wang P, Meng S, Chu S, Li Z, Guo Q, Zheng J, Bai J, Li H
Cell death & disease 2023 May 12;14(5):322
Cell death & disease 2023 May 12;14(5):322
Microtubule-associated protein 4 promotes epithelial mesenchymal transition in hepatocellular cancer cells via regulating GSK3β/β-catenin pathway.
Hu P, Zong B, Chen Q, Shao R, Chen M, Yang Y, Shao G
Heliyon 2023 Mar;9(3):e14309
Heliyon 2023 Mar;9(3):e14309
Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity.
Zhao H, Tang S, Tao Q, Ming T, Lei J, Liang Y, Peng Y, Wang M, Liu M, Yang H, Ren S, Xu H
Journal of agricultural and food chemistry 2023 Mar 8;71(9):3981-3993
Journal of agricultural and food chemistry 2023 Mar 8;71(9):3981-3993
The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury.
Chen Z, He S, Lian S, Shen Y, Jiang W, Zhou L, Zhou L, Zhang X
Bioscience reports 2023 Mar 31;43(3)
Bioscience reports 2023 Mar 31;43(3)
Pan-cancer analysis of PCAT6 and its effect on oesophageal squamous cell carcinoma cell proliferation and migration.
Luo Q, Kuang Y, Tao X, Zhu X, Zhao X, Lu G, Zhang W, Sun E, Chen B
Medical oncology (Northwood, London, England) 2023 Mar 22;40(4):125
Medical oncology (Northwood, London, England) 2023 Mar 22;40(4):125
Human umbilical cord mesenchymal stem cells conditioned medium exerts anti-tumor effects on KGN cells in a cell density-dependent manner through activation of the Hippo pathway.
Wan W, Miao Y, Niu Y, Zhu K, Ma Y, Pan M, Ma B, Wei Q
Stem cell research & therapy 2023 Mar 20;14(1):46
Stem cell research & therapy 2023 Mar 20;14(1):46
Ursolic acid nanoparticles for glioblastoma therapy.
Li Y, Zhao L, Zhao Q, Zhou Y, Zhou L, Song P, Liu B, Chen Q, Deng G
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102684
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102684
MicroRNA-137 inhibits pituitary prolactinoma proliferation by targeting AKT2.
Xu Q, Yu ZX, Xie YL, Bai L, Liang SR, Ji QH, Zhou J
Journal of endocrinological investigation 2023 Jun;46(6):1145-1154
Journal of endocrinological investigation 2023 Jun;46(6):1145-1154
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway.
Sun Y, Weng J, Chen X, Ma S, Zhang Y, Zhang F, Zhang Z, Wang F, Shao J, Zheng S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114653
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114653
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
Yi Q, Zhao Y, Xia R, Wei Q, Chao F, Zhang R, Bian P, Lv L
Cell death discovery 2023 Jun 26;9(1):191
Cell death discovery 2023 Jun 26;9(1):191
Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.
Fan TW, Winnike J, Al-Attar A, Belshoff AC, Lorkiewicz PK, Tan JL, Wu M, Higashi RM, Lane AN
Metabolites 2023 Jun 21;13(7)
Metabolites 2023 Jun 21;13(7)
HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
Ma H, Qi G, Han F, Gai P, Peng J, Kong B
Cell communication and signaling : CCS 2023 Jun 16;21(1):144
Cell communication and signaling : CCS 2023 Jun 16;21(1):144
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma.
Miao Y, Wang X, Lai Y, Huang Y, Yin H, Meng X, Liu H, Hou R, Lin W, Zhang X, Zhang X, Chai BC, Zhang F, Guo L, Yang S
International journal of oncology 2023 Jul;63(1)
International journal of oncology 2023 Jul;63(1)
eIF3a sustains non-small cell lung cancer stem cell-like properties by promoting YY1-mediated transcriptional activation of β-catenin.
Zheng JY, Zhu T, Zhuo W, Mao XY, Yin JY, Li X, He YJ, Zhang W, Liu C, Liu ZQ
Biochemical pharmacology 2023 Jul;213:115616
Biochemical pharmacology 2023 Jul;213:115616
Ethyl acetate extract of Antenoron Filiforme inhibits the proliferation of triple negative breast cancer cells via suppressing Skp2/p21 signaling axis.
Liao Y, Li S, An J, Yu X, Tan X, Gui Y, Wang Y, Huang L, Zhou S, Wang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154856
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154856
Targeting CDK12 obviates the malignant phenotypes of colorectal cancer through the Wnt/β-catenin signaling pathway.
Liu S, Wu J, Lu X, Guo C, Zheng Q, Wang Y, Hu Q, Bian S, Luo L, Cheng Q, Liu Z, Dai W
Experimental cell research 2023 Jul 1;428(1):113613
Experimental cell research 2023 Jul 1;428(1):113613
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Chen W, Yu H, Sun C, Dong M, Zhao N, Wang Y, Yu K, Zhang J, Xu N, Liu W
Toxicology letters 2023 Jul 1;383:177-191
Toxicology letters 2023 Jul 1;383:177-191
ZYY-B-2, a novel ALK inhibitor, overcomes resistance to ceritinib by inhibiting P-gp function and induces apoptosis through mitochondrial pathway in ceritinib-resistant H2228 cells.
Gao Y, Liu T, Liu J, Yang Y, Sun K, Li Z, Zhai X, Zuo D
Chemico-biological interactions 2023 Jul 1;379:110516
Chemico-biological interactions 2023 Jul 1;379:110516
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
Ye Z, Xia Y, Li L, Li B, Chen W, Han S, Zhou X, Chen L, Yu W, Ruan Y, Cheng F
Translational oncology 2023 Jan;27:101578
Translational oncology 2023 Jan;27:101578
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
Zhao D, Gao Y, Su Y, Zhou Y, Yang T, Li Y, Wang Y, Sun Y, Chen L, Zhang F, Zhang Z, Wang F, Shao J, Zheng S
Pharmacological research 2023 Jan;187:106590
Pharmacological research 2023 Jan;187:106590
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Liu H, Yu L, Ding Y, Peng M, Deng Y
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
Yin W, Fu X, Chang W, Han L, Meng J, Cao A, Ren X, Fan Z, Zhou S
The Journal of pharmacy and pharmacology 2023 Jan 31;75(1):87-97
The Journal of pharmacy and pharmacology 2023 Jan 31;75(1):87-97
Analysis of Promoter Methylation of the Bovine FOXO1 Gene and Its Effect on Proliferation and Differentiation of Myoblasts.
Shi P, Ruan Y, Liu W, Sun J, Xu J, Xu H
Animals : an open access journal from MDPI 2023 Jan 16;13(2)
Animals : an open access journal from MDPI 2023 Jan 16;13(2)
Triptonide inhibits growth and metastasis in HCC by suppressing EGFR/PI3K/AKT signaling.
Zhang H, Mao Y, Zou X, Niu J, Jiang J, Chen X, Zhu M, Yang X, Dong T
Neoplasma 2023 Feb;70(1):94-102
Neoplasma 2023 Feb;70(1):94-102
Effects of the CDC10 (Septin 7) Gene on the Proliferation and Differentiation of Bovine Intramuscular Preadipocyte and 3T3-L1 Cells.
Cheng Z, Li X, Bao S, Yamada T, Cao G, Liu J, Chen A, Tong B
Animals : an open access journal from MDPI 2023 Feb 9;13(4)
Animals : an open access journal from MDPI 2023 Feb 9;13(4)
Krüppel-like Factor 7 inhibits proliferation and migration of pulmonary smooth muscle cells via p21 activation.
Zeng Z, Zhou X, Zhu Y, Huang X, Tong X, Liu J, Zhang T, Wu W
European journal of pharmacology 2023 Feb 5;940:175473
European journal of pharmacology 2023 Feb 5;940:175473
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening.
Deng L, Yang L, Zhu S, Li M, Wang Y, Cao X, Wang Q, Guo L
Cell death discovery 2023 Feb 2;9(1):40
Cell death discovery 2023 Feb 2;9(1):40
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Zhou C, Zhu X, Liu N, Dong X, Zhang X, Huang H, Tang Y, Liu S, Hu M, Wang M, Deng X, Li S, Zhang R, Huang Y, Lyu H, Xiao S, Luo S, Ali DW, Michalak M, Chen XZ, Wang Z, Tang J
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1.
Li J, Zhao B, Yao S, Dai Y, Zhang X, Yang N, Bao Z, Cai J, Chen Y, Wu X
International journal of molecular sciences 2023 Feb 16;24(4)
International journal of molecular sciences 2023 Feb 16;24(4)
ANXA3, associated with YAP1 regulation, participates in the proliferation and chemoresistance of cervical cancer cells.
Huang J, Wei W, Kang F, Tan S, Li Y, Lu X, Wang N
Genes & genomics 2023 Dec;45(12):1575-1586
Genes & genomics 2023 Dec;45(12):1575-1586
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
Bai Y, Zhou L, Zhang C, Guo M, Xia L, Tang Z, Liu Y, Deng S
Oncogene 2023 Dec;42(49):3605-3618
Oncogene 2023 Dec;42(49):3605-3618
Effects of dietary folic acid supplementation on lactation performance and mammary epithelial cell development of dairy cows and its regulatory mechanism.
Zhang J, Liu YP, Bu LJ, Liu Q, Pei CX, Huo WJ
Animal biotechnology 2023 Dec;34(8):3796-3807
Animal biotechnology 2023 Dec;34(8):3796-3807
Exogenous H(2)S alleviates senescence of glomerular mesangial cells through up-regulating mitophagy by activation of AMPK-ULK1-PINK1-parkin pathway in mice.
E Y, Lin Y, Yan G, Yang J, Jiao L, Wu R, Yan Q, Chen Y, Chen Y, Yan X, Li H
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119568
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119568
NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis.
Peng Y, Zhang Y, Luo M, Pan Y, Zhou R, Yan YN, Yi T, Luo F, Wang B, Wang L, Ran C, Wang H
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119525
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119525
TC2N Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Targeting the Wnt/β-Catenin Signaling Pathway.
Lou YX, Gu J, Zhu L, Sun SQ, Hao XL, Chen JP, Han F, Wang DD, Jiang X, Liu JY
Laboratory investigation; a journal of technical methods and pathology 2023 Dec;103(12):100260
Laboratory investigation; a journal of technical methods and pathology 2023 Dec;103(12):100260
LINC00921 reduces lung cancer radiosensitivity by destabilizing NUDT21 and driving aberrant MED23 alternative polyadenylation.
Zhang N, Liu X, Huang L, Zeng J, Ma C, Han L, Li W, Yu J, Yang M
Cell reports 2023 Dec 26;42(12):113479
Cell reports 2023 Dec 26;42(12):113479
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Bao H, Peng Z, Cheng X, Jian C, Li X, Shi Y, Zhu W, Hu Y, Jiang M, Song J, Fang F, Chen J, Shu X
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Aberrant epithelial cell interaction promotes esophageal squamous-cell carcinoma development and progression.
Chen L, Zhu S, Liu T, Zhao X, Xiang T, Hu X, Wu C, Lin D
Signal transduction and targeted therapy 2023 Dec 15;8(1):453
Signal transduction and targeted therapy 2023 Dec 15;8(1):453
CD56 polysialylation promotes the tumorigenesis and progression via the Hedgehog and Wnt/β-catenin signaling pathways in clear cell renal cell carcinoma.
Jian Y, Zhang L, Gong L, Ding M, Sun X, Yu X, Lv S, Li J, Yang D, Wang S
Cancer cell international 2023 Dec 12;23(1):319
Cancer cell international 2023 Dec 12;23(1):319
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer.
Tian W, Tang Y, Luo Y, Xie J, Zheng S, Zou Y, Huang X, Wu L, Zhang J, Sun Y, Tang H, Du W, Li X, Xie X
Cell death & disease 2023 Dec 1;14(12):790
Cell death & disease 2023 Dec 1;14(12):790
Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.
Zhang X, Wu N, Huang H, Li S, Liu S, Zhang R, Huang Y, Lyu H, Xiao S, Ali DW, Michalak M, Chen XZ, Zhou C, Tang J
Oncogene 2023 Aug;42(32):2439-2455
Oncogene 2023 Aug;42(32):2439-2455
Lysine-Specific Demethylase 4D Is Critical for the Regulation of the Cell Cycle and Antioxidant Capacity in Goat Fibroblast Cells.
Chen X, Yang Y, Cai Y, Yang H, Wang F, Deng M
Biology 2023 Aug 7;12(8)
Biology 2023 Aug 7;12(8)
Histone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia.
Wang H, Qiu Y, Zhang H, Chang N, Hu Y, Chen J, Hu R, Liao P, Li Z, Yang Y, Cen Q, Ding X, Li M, Xie X, Li Y
Cell death & disease 2023 Aug 4;14(8):498
Cell death & disease 2023 Aug 4;14(8):498
High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.
Chen YT, Chung CL, Cheng YW, Lin CJ, Tseng TT, Hsu SS, Tsai HP, Kwan AL
International journal of molecular sciences 2023 Aug 29;24(17)
International journal of molecular sciences 2023 Aug 29;24(17)
Knockdown of KDM5B Leads to DNA Damage and Cell Cycle Arrest in Granulosa Cells via MTF1.
Yang Y, Cai Y, Guo J, Dai K, Liu L, Chen Z, Wang F, Deng M
Current issues in molecular biology 2023 Apr 7;45(4):3219-3237
Current issues in molecular biology 2023 Apr 7;45(4):3219-3237
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer.
Yang H, Pu L, Li R, Zhu R
Journal of gastrointestinal oncology 2023 Apr 29;14(2):900-912
Journal of gastrointestinal oncology 2023 Apr 29;14(2):900-912
8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells.
Zhang D, Fu Y, Liu Y, Wu Y, Chen J, Zhang L, Wang R, Chen Z, Liu T
International journal of molecular sciences 2023 Apr 28;24(9)
International journal of molecular sciences 2023 Apr 28;24(9)
Septin11 promotes hepatocellular carcinoma cell motility by activating RhoA to regulate cytoskeleton and cell adhesion.
Fu L, Wang X, Yang Y, Chen M, Kuerban A, Liu H, Dong Y, Cai Q, Ma M, Wu X
Cell death & disease 2023 Apr 20;14(4):280
Cell death & disease 2023 Apr 20;14(4):280
Upregulation of TMEM40 is associated with the malignant behavior and promotes tumor progression in cervical cancer.
Zhang ZF, Liu F, Zhang HR, Liu B, Zheng SQ, Ye WQ, Ding JN, Zhou ZJ, Luo HX, Wu F, Guo XM, Zhou JY, Guo YH
Discover oncology 2023 Apr 13;14(1):43
Discover oncology 2023 Apr 13;14(1):43
Structural Characterization and Anti-breast Cancer Activity in vitro of a Novel Polysaccharide From Cymbopogon citratus.
Chen Y, Qiao S, Liu H, Xing H, Chen P
Frontiers in nutrition 2022;9:911838
Frontiers in nutrition 2022;9:911838
Intervention Mechanism of Hunag-Lian Jie-Du Decoction on Canonical Wnt/β-Catenin Signaling Pathway in Psoriasis Mouse Model.
Yang X, Luo G, Fu L, Huang H, Wang L, Yin L, Zhang X, Wang T, Ma X, Feng T, Ye J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3193572
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3193572
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
Li J, Yang T, Wang Q, Li Y, Wu H, Zhang M, Qi H, Zhang H, Li J
International journal of biological sciences 2022;18(9):3576-3591
International journal of biological sciences 2022;18(9):3576-3591
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.
Peng S, Chen X, Huang C, Yang C, Situ M, Zhou Q, Ling Y, Huang H, Huang M, Zhang Y, Cheng L, Zhang Q, Guo Z, Lai Y, Huang J
International journal of biological sciences 2022;18(8):3528-3543
International journal of biological sciences 2022;18(8):3528-3543
CCDC65, a Gene Knockout that leads to Early Death of Mice, acts as a potentially Novel Tumor Suppressor in Lung Adenocarcinoma.
Zhang Z, Xu P, Hu Z, Fu Z, Deng T, Deng X, Peng L, Xie Y, Long L, Zheng D, Shen P, Zhang M, Gong B, Zhu Z, Lin J, Chen R, Liu Z, Yang H, Li R, Fang W
International journal of biological sciences 2022;18(10):4171-4186
International journal of biological sciences 2022;18(10):4171-4186
CAMTA1 gene affects the ischemia-reperfusion injury by regulating CCND1.
Liu Y, Shang G, Zhang X, Liu F, Zhang C, Li Z, Jia J, Xu Y, Zhang Z, Yang S, Zhou B, Luan Y, Huang Y, Peng Y, Han T, He Y, Zheng H
Frontiers in cellular neuroscience 2022;16:868291
Frontiers in cellular neuroscience 2022;16:868291
Chrysin Ameliorates Influenza Virus Infection in the Upper Airways by Repressing Virus-Induced Cell Cycle Arrest and Mitochondria-Dependent Apoptosis.
Liu Y, Song X, Li C, Hu H, Li W, Wang L, Hu J, Liao C, Liang H, He Z, Ye L
Frontiers in immunology 2022;13:872958
Frontiers in immunology 2022;13:872958
METTL3/m(6)A/IFIT2 regulates proliferation, invasion and immunity in esophageal squamous cell carcinoma.
Ge F, Li Z, Hu J, Pu Y, Zhao F, Kong L
Frontiers in pharmacology 2022;13:1002565
Frontiers in pharmacology 2022;13:1002565
Targeting type Iγ phosphatidylinositol phosphate kinase overcomes oxaliplatin resistance in colorectal cancer.
Yu M, Wang H, Zhao W, Ge X, Huang W, Lin F, Tang W, Li A, Liu S, Li RK, Jiang SH, Xue J
Theranostics 2022;12(9):4386-4398
Theranostics 2022;12(9):4386-4398
E2F1-mediated GINS2 transcriptional activation promotes tumor progression through PI3K/AKT/mTOR pathway in hepatocellular carcinoma.
Zhang Y, Hao X, Han G, Lu Y, Chen Z, Zhang L, Wu J, Wang X
American journal of cancer research 2022;12(4):1707-1726
American journal of cancer research 2022;12(4):1707-1726
INPP4B inhibits glioma cell proliferation and immune escape via inhibition of the PI3K/AKT signaling pathway.
Sun X, Chen Y, Tao X, Zhang W, Wang X, Wang X, Ruan Z, Chen Z
Frontiers in oncology 2022;12:983537
Frontiers in oncology 2022;12:983537
Synergistic effects of nab-PTX and anti-PD-1 antibody combination against lung cancer by regulating the Pi3K/AKT pathway through the Serpinc1 gene.
Zhang J, Tang Z, Guo X, Wang Y, Zhou Y, Cai W
Frontiers in oncology 2022;12:933646
Frontiers in oncology 2022;12:933646
Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.
Yu M, Jia Y, Ma Z, Ji D, Wang C, Liang Y, Zhang Q, Yi H, Zeng L
Frontiers in oncology 2022;12:906807
Frontiers in oncology 2022;12:906807
Increased Methyl-CpG-Binding Domain Protein 2 Promotes Cigarette Smoke-Induced Pulmonary Hypertension.
Wu J, Huang Q, Li Q, Gu Y, Zhan Y, Wang T, Chen J, Zeng Z, Lv Y, Zhao J, Xia J, Xie J
Frontiers in oncology 2022;12:879793
Frontiers in oncology 2022;12:879793
HRK inhibits colorectal cancer cells proliferation by suppressing the PI3K/AKT/mTOR pathway.
Wang H, Chen Y, Yuan Q, Chen L, Dai P, Li X
Frontiers in oncology 2022;12:1053510
Frontiers in oncology 2022;12:1053510
Identification and validation of a potential key gene SGOL1 for poor prognosis in hepatocellular carcinoma based on a bioinformatics approach.
Fei X, Liu S, Liu P, Wang X, Zhu C, Hou J, Cai J, Pan Y
Frontiers in oncology 2022;12:1043161
Frontiers in oncology 2022;12:1043161
A long noncoding RNA GTF2IRD2P1 suppresses cell proliferation in bladder cancer by inhibiting the Wnt/β‑catenin signaling pathway.
Huang Z, Gao H, Qing L, Wang B, He C, Luo N, Lu C, Fan S, Gu P, Zhao H
PeerJ 2022;10:e13220
PeerJ 2022;10:e13220
SERPINA5 promotes tumour cell proliferation by modulating the PI3K/AKT/mTOR signalling pathway in gastric cancer.
Fan M, Xiong X, Han L, Zhang L, Gao S, Liu L, Wang X, Huang C, Tong D, Yang J, Zhao L, Shao Y
Journal of cellular and molecular medicine 2022 Sep;26(18):4837-4846
Journal of cellular and molecular medicine 2022 Sep;26(18):4837-4846
Combined treatment with dihydrotestosterone and lipopolysaccharide modulates prostate homeostasis by upregulating TNF-α from M1 macrophages and promotes proliferation of prostate stromal cells.
Tong Y, Guo YJ, Zhang Q, Bi HX, Kai K, Zhou RY
Asian journal of andrology 2022 Sep-Oct;24(5):513-520
Asian journal of andrology 2022 Sep-Oct;24(5):513-520
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
Gu H, Zhu S, Peng C, Wei Z, Shen Y, Yuan C, Yang H, Cui H, Yang L
International journal of molecular sciences 2022 Sep 5;23(17)
International journal of molecular sciences 2022 Sep 5;23(17)
Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.
Wang Z, Wang MM, Geng Y, Ye CY, Zang YS
Journal of translational medicine 2022 Sep 5;20(1):402
Journal of translational medicine 2022 Sep 5;20(1):402
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
Xing J, Chen W, Chen K, Zhu S, Lin F, Qi Y, Zhang Y, Han S, Rao T, Ruan Y, Zhao S, Yu W, Cheng F
Cancers 2022 Sep 30;14(19)
Cancers 2022 Sep 30;14(19)
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
Li H, Li K, Shu D, Shen M, Tan Z, Zhang W, Pu D, Tan W, Tang Z, Jin A, Liu S
Life (Basel, Switzerland) 2022 Sep 20;12(10)
Life (Basel, Switzerland) 2022 Sep 20;12(10)
Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation through the Chi-miR-214-3p/β-Catenin Axis in Cashmere Goats.
Zhang Y, Li F, Shi Y, Zhang T, Wang X
International journal of molecular sciences 2022 Sep 2;23(17)
International journal of molecular sciences 2022 Sep 2;23(17)
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Yao H, Ren D, Wang Y, Wu L, Wu Y, Wang W, Li Q, Liu L
Cell death & disease 2022 Sep 2;13(9):761
Cell death & disease 2022 Sep 2;13(9):761
Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE.
Ye C, Li H, Li Y, Zhang Y, Liu G, Mi H, Li H, Xiao Q, Niu L, Yu X
iScience 2022 Sep 16;25(9):104872
iScience 2022 Sep 16;25(9):104872
Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy.
Bian Y, Shi C, Song S, Mu L, Wu M, Qiu D, Dong J, Zhang W, Yuan C, Wang D, Zhou Z, Dong X, Shi Y
Cell and tissue research 2022 Oct;390(1):93-112
Cell and tissue research 2022 Oct;390(1):93-112
CTPS cytoophidia formation affects cell cycle progression and promotes TSN‑induced apoptosis of MKN45 cells.
Fu X, Chen W, Pan Y, Liu C, Zhang Z, Shao S, Zhang W
Molecular medicine reports 2022 Oct;26(4)
Molecular medicine reports 2022 Oct;26(4)
HCV Core protein represses DKK3 expression via epigenetic silencing and activates the Wnt/β-catenin signaling pathway during the progression of HCC.
Wang X, Zhou Y, Wang C, Zhao Y, Cheng Y, Yu S, Li X, Zhang W, Zhang Y, Quan H
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Oct;24(10):1998-2009
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Oct;24(10):1998-2009
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Liang W, Chen Q, Cheng S, Wei R, Li Y, Yao C, Ouyang Z, Kang D, Chen A, Liu Z, Li K, Bai X, Li Q, Huang B
Nature aging 2022 Oct;2(10):906-922
Nature aging 2022 Oct;2(10):906-922
Transfer RNA-derived fragment 5'tRF-Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen-related cell adhesion molecule 1.
Liu D, Wu C, Wang J, Zhang L, Sun Z, Chen S, Ding Y, Wang W
Cancer science 2022 Oct;113(10):3476-3488
Cancer science 2022 Oct;113(10):3476-3488
RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
Xu J, Shi P, Xia F, Zhao X, Chen J, Geng R, Cui H, Yang L
International journal of molecular sciences 2022 Oct 10;23(19)
International journal of molecular sciences 2022 Oct 10;23(19)
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Fang J, Ma Y, Li Y, Li J, Zhang X, Han X, Ma S, Guan F
Molecular carcinogenesis 2022 Nov;61(11):1043-1055
Molecular carcinogenesis 2022 Nov;61(11):1043-1055
Hepatocyte-derived VEGFA accelerates the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via activating hepatic stellate cells.
Shen H, Yu H, Li QY, Wei YT, Fu J, Dong H, Cao D, Guo LN, Chen L, Yang Y, Xu Y, Wu MC, Wang HY, Chen Y
Acta pharmacologica Sinica 2022 Nov;43(11):2917-2928
Acta pharmacologica Sinica 2022 Nov;43(11):2917-2928
Lysine stimulates the development of the murine mammary gland at puberty via PI3K/AKT/mTOR signalling axis.
Li W, Long X, Li F, Cao Y, Liu J, Fu S, Guo W, Hu G
Journal of animal physiology and animal nutrition 2022 Nov;106(6):1420-1430
Journal of animal physiology and animal nutrition 2022 Nov;106(6):1420-1430
Blockade of c-Met-Mediated Signaling Pathways by E7050 Suppresses Growth and Promotes Apoptosis in Multidrug-Resistant Human Uterine Sarcoma Cells.
Huang TT, Chen CM, Lan YW, Lin SS, Choo KB, Chong KY
International journal of molecular sciences 2022 Nov 28;23(23)
International journal of molecular sciences 2022 Nov 28;23(23)
Discovery of a Novel Bloom's Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer.
Ma XY, Xu HQ, Zhao JF, Ruan Y, Chen B
International journal of molecular sciences 2022 Nov 26;23(23)
International journal of molecular sciences 2022 Nov 26;23(23)
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
Peng T, Liu M, Hu L, Guo D, Wang D, Qi B, Ren G, Hu C, Zhang F, Chun HJ, Song L, Hu J, Li Y
Biology direct 2022 Nov 16;17(1):32
Biology direct 2022 Nov 16;17(1):32
Potential mechanisms underlying the promoting effects of 3D collagen scaffold culture on stemness and drug resistance of glioma cells.
Jia W, Zhu H, Zhao M, Zhou Q, Yin W, Liu W, Wang L, Xiao Z, Jiang X, Dai J, Ren C
Biochimica et biophysica acta. Molecular basis of disease 2022 Nov 1;1868(11):166522
Biochimica et biophysica acta. Molecular basis of disease 2022 Nov 1;1868(11):166522
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Huang Z, Chen H, Tan P, Huang M, Shi H, Sun B, Cheng Y, Li T, Mou Z, Li Q, Fu W
Drug development research 2022 May;83(3):721-734
Drug development research 2022 May;83(3):721-734
Skimmianine as a novel therapeutic agent suppresses proliferation and migration of human esophageal squamous cell carcinoma via blocking the activation of ERK1/2.
Liu Y, Kang L, Shi SM, Li BJ, Zhang Y, Zhang XZ, Guo XW, Fu G, Zheng GN, Hao H, Zhao HF
Neoplasma 2022 May;69(3):571-582
Neoplasma 2022 May;69(3):571-582
The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway.
Yu W, Xu G, Chen H, Xiao L, Liu G, Hu P, Li S, Kasim V, Zeng C, Tong X
Acta pharmaceutica Sinica. B 2022 May;12(5):2315-2329
Acta pharmaceutica Sinica. B 2022 May;12(5):2315-2329
In vitro and in vivo anti-lymphoma effects of Ophiorrhiza pumila extract.
Fan L, Liao W, Chen Z, Li S, Yang A, Chen MM, Liu H, Liu F
Aging 2022 May 3;14(9):3801-3812
Aging 2022 May 3;14(9):3801-3812
Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.
Zheng ZY, Chu MY, Lin W, Zheng YQ, Xu XE, Chen Y, Liao LD, Wu ZY, Wang SH, Li EM, Xu LY
Cell death & disease 2022 May 25;13(5):496
Cell death & disease 2022 May 25;13(5):496
Arylquin 1 (Potent Par-4 Secretagogue) Inhibits Tumor Progression and Induces Apoptosis in Colon Cancer Cells.
Chen YT, Tseng TT, Tsai HP, Huang MY
International journal of molecular sciences 2022 May 18;23(10)
International journal of molecular sciences 2022 May 18;23(10)
Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway.
Zhao B, Li J, Zhang X, Dai Y, Yang N, Bao Z, Chen Y, Wu X
International journal of biological macromolecules 2022 May 15;207:110-120
International journal of biological macromolecules 2022 May 15;207:110-120
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
Xu H, Cui Y, Liu X, Zheng X, Liu J, Hu X, Gao F, Hu X, Li M, Wei X, Gao Y, Zhao Y
Molecular biology reports 2022 Mar;49(3):1871-1882
Molecular biology reports 2022 Mar;49(3):1871-1882
A novel mechanism of the lncRNA PTTG3P/miR-142-5p/JAG1 axis modulating tongue cancer cell phenotypes through the Notch1 signaling.
Zhang T, Liu X, Su K, Zheng Q, Liu P, Xu Z, Zhang Y
Cells & development 2022 Mar;169:203762
Cells & development 2022 Mar;169:203762
Cyclin D1 mediated by the nuclear translocation of nuclear factor kappa B exerts an oncogenic role in lung cancer.
Wang X, Liu X, Yang Y, Yang D
Bioengineered 2022 Mar;13(3):6866-6879
Bioengineered 2022 Mar;13(3):6866-6879
Pseudophosphatase STYX is induced by Helicobacter pylori and promotes gastric cancer progression by inhibiting FBXO31 function.
Liu J, Zang Y, Ma C, Wang D, Tian Z, Xu X, Li W, Jia J, Liu Z
Cell death & disease 2022 Mar 25;13(3):268
Cell death & disease 2022 Mar 25;13(3):268
Long noncoding RNA Gm31629 protects against mucosal damage in experimental colitis via YB-1/E2F pathway.
Feng X, Xiao Y, He J, Yang M, Guo Q, Su T, Huang Y, Yi J, Li CJ, Luo XH, Liu XW, Zhou HY
JCI insight 2022 Mar 22;7(6)
JCI insight 2022 Mar 22;7(6)
HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway.
Guo K, Ma Z, Zhang Y, Han L, Shao C, Feng Y, Gao F, Di S, Zhang Z, Zhang J, Tabbò F, Ekman S, Suda K, Cappuzzo F, Han J, Li X, Yan X
Journal of experimental & clinical cancer research : CR 2022 Mar 11;41(1):91
Journal of experimental & clinical cancer research : CR 2022 Mar 11;41(1):91
Transcription Factor Specificity Protein 1 Regulates Inflammation and Fibrin Deposition in Nasal Polyps Via the Regulation of microRNA-125b and the Wnt/β-catenin Signaling Pathway.
Song L, Wang X, Qu X, Lv C
Inflammation 2022 Jun;45(3):1118-1132
Inflammation 2022 Jun;45(3):1118-1132
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
Ji R, Shi Q, Cao Y, Zhang J, Zhao C, Zhao H, Sayyed Y, Fu L, Li LY
The Journal of biological chemistry 2022 Jun;298(6):102033
The Journal of biological chemistry 2022 Jun;298(6):102033
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H(2)S in Diabetes.
Xi Y, Wen X, Zhang Y, Jiao L, Bai S, Shi S, Chang G, Wu R, Sun F, Hao J, Li H
Aging and disease 2022 Jun;13(3):910-926
Aging and disease 2022 Jun;13(3):910-926
Paired box 8 facilitates the c-MYC related cell cycle progress in TP53-mutation uterine corpus endometrial carcinoma through interaction with DDX5.
Qiu P, Jie Y, Ma C, Chen H, Qin Y, Tu K, Wang L, Zhang Z
Cell death discovery 2022 Jun 7;8(1):276
Cell death discovery 2022 Jun 7;8(1):276
Near-Infrared Light-Responsive Nanoinhibitors for Tumor Suppression through Targeting and Regulating Anion Channels.
Li C, Shi S, Gao D, Li B, Song G, Chen Y, An H, Xing C
ACS applied materials & interfaces 2022 Jul 20;14(28):31715-31726
ACS applied materials & interfaces 2022 Jul 20;14(28):31715-31726
Caffeic Acid, an Active Ingredient in Coffee, Combines with DOX for Multitarget Combination Therapy of Lung Cancer.
Bai X, Li S, Liu X, An H, Kang X, Guo S
Journal of agricultural and food chemistry 2022 Jul 13;70(27):8326-8337
Journal of agricultural and food chemistry 2022 Jul 13;70(27):8326-8337
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Li H, Sun F, Bai S, Chang G, Wu R, Wei Y, Wen X, Xi Y, Hao J, Zaid A
International journal of molecular medicine 2022 Jan;49(1)
International journal of molecular medicine 2022 Jan;49(1)
Knockdown of EphB3 inhibits cell proliferation partly through the AKT signaling pathway and represses epithelial-mesenchymal transition in esophageal squamous cell carcinoma.
Tang L, Wang L, Yu T, Xu T, Zhang L, Shu Y
Translational cancer research 2022 Jan;11(1):85-98
Translational cancer research 2022 Jan;11(1):85-98
Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies.
Wu X, Wang Y, Fan X, Xu X, Sun W
Aging 2022 Jan 7;14(1):410-429
Aging 2022 Jan 7;14(1):410-429
Betulinic acid self-assembled nanoparticles for effective treatment of glioblastoma.
Li Y, Wang Y, Gao L, Tan Y, Cai J, Ye Z, Chen AT, Xu Y, Zhao L, Tong S, Sun Q, Liu B, Zhang S, Tian D, Deng G, Zhou J, Chen Q
Journal of nanobiotechnology 2022 Jan 21;20(1):39
Journal of nanobiotechnology 2022 Jan 21;20(1):39
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
He X, Wang J, Zhou R, Yu S, Jiang J, Zhou Q
Toxicology and applied pharmacology 2022 Jan 15;435:115834
Toxicology and applied pharmacology 2022 Jan 15;435:115834
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
Jin YM, Ye Y, Bao WQ, Tong Y, Ni SB, Liu JP, Zhao B
Journal of receptor and signal transduction research 2022 Feb;42(1):1-8
Journal of receptor and signal transduction research 2022 Feb;42(1):1-8
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
Tang W, Xue J, Luo L, Wang Y, Cai X, Liu Y, Huang D, Wang X, He T, Lu D, Yang F
Molecular medicine reports 2022 Feb;25(2)
Molecular medicine reports 2022 Feb;25(2)
PRUNE2 inhibits progression of colorectal cancer in vitro and in vivo.
Li T, Huang S, Yan W, Zhang Y, Guo Q
Experimental and therapeutic medicine 2022 Feb;23(2):169
Experimental and therapeutic medicine 2022 Feb;23(2):169
The miR-34a/WNT7B modulates the sensitivity of cholangiocarcinoma cells to p53-mediated photodynamic therapy toxicity.
Han Y, Yang Y, Huang S, Yao L, Wu L
Biochemical and biophysical research communications 2022 Feb 5;591:54-61
Biochemical and biophysical research communications 2022 Feb 5;591:54-61
FERMT1 contributes to the migration and invasion of nasopharyngeal carcinoma through epithelial-mesenchymal transition and cell cycle arrest.
Li L, Li P, Zhang W, Zhou H, Guo E, Hu G, Zhang L
Cancer cell international 2022 Feb 10;22(1):70
Cancer cell international 2022 Feb 10;22(1):70
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
Qin J, Sun X, Ma Y, Cheng Y, Ma Q, Jing W, Qu S, Liu L
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Xu M, Ren L, Fan J, Huang L, Zhou L, Li X, Ye X
Life sciences 2022 Feb 1;290:120266
Life sciences 2022 Feb 1;290:120266
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Bian Y, Xue M, Guo X, Jiang W, Zhao Y, Zhang Z, Wang X, Hu Y, Zhang Q, Dun W, Zhang L
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Characterization and functional analysis of lncRNA2690 in regulating the growth cycle of the hair follicle in rabbits.
Bao Z, Zhai P, Yao F, Ren Y, Zhao B, Chen Y, Wu X
Animal genetics 2022 Dec;53(6):841-848
Animal genetics 2022 Dec;53(6):841-848
ALG8 Fuels Stemness Through Glycosylation of the WNT/Beta-Catenin Signaling Pathway in Colon Cancer.
Wu X, Wang B, Su Y, He D, Mo H, Zheng M, Meng Z, Ren L, Zhang X, Ren D, Li C
DNA and cell biology 2022 Dec;41(12):1075-1083
DNA and cell biology 2022 Dec;41(12):1075-1083
PRRX1 promotes colorectal cancer stemness and chemoresistance via the JAK2/STAT3 axis by targeting IL-6.
Zhong L, Tan W, Yang Q, Zou Z, Zhou R, Huang Y, Qiu Z, Zheng K, Huang Z
Journal of gastrointestinal oncology 2022 Dec;13(6):2989-3008
Journal of gastrointestinal oncology 2022 Dec;13(6):2989-3008
miR-29b-3p inhibits 22Rv1 prostate cancer cell proliferation through the YWHAE/BCL-2 regulatory axis.
Zhao J, Ma X, Xu H
Oncology letters 2022 Aug;24(2):289
Oncology letters 2022 Aug;24(2):289
NSUN2-mediated RNA m(5)C modification modulates uveal melanoma cell proliferation and migration.
Luo G, Xu W, Chen X, Wang S, Wang J, Dong F, Hu DN, Reinach PS, Yan D
Epigenetics 2022 Aug;17(8):922-933
Epigenetics 2022 Aug;17(8):922-933
LAP3 contributes to IFN-γ-induced arginine depletion and malignant transformation of bovine mammary epithelial cells.
Li L, Li F, Hu X, Wu Z, Ren W, Wang T, Ji Z, Li N, Gu J, Sun C, Feng X, Han W, Huang J, Lei L
BMC cancer 2022 Aug 8;22(1):864
BMC cancer 2022 Aug 8;22(1):864
lncRNA2919 Suppresses Rabbit Dermal Papilla Cell Proliferation via trans-Regulatory Actions.
Zhao B, Li J, Liu M, Hu S, Yang N, Liang S, Zhang X, Dai Y, Bao Z, Chen Y, Wu X
Cells 2022 Aug 6;11(15)
Cells 2022 Aug 6;11(15)
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Hu P, Xu Y, Jiang Y, Huang J, Liu Y, Wang D, Tao T, Sun Z, Liu Y
European journal of pharmacology 2022 Aug 5;928:175093
European journal of pharmacology 2022 Aug 5;928:175093
S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c-Myc pathway in patients with estrogen receptor-positive breast cancer.
Mo H, Liu X, Xue Y, Chen H, Guo S, Li Z, Wang S, Li C, Han J, Fu M, Song Y, Li D, Ma F
Molecular cancer 2022 Aug 30;21(1):171
Molecular cancer 2022 Aug 30;21(1):171
DNA Methylation Mediates lncRNA2919 Regulation of Hair Follicle Regeneration.
Zhao B, Li J, Liu M, Yang N, Bao Z, Zhang X, Dai Y, Cai J, Chen Y, Wu X
International journal of molecular sciences 2022 Aug 22;23(16)
International journal of molecular sciences 2022 Aug 22;23(16)
The effects of Jiawei Duhuo Jisheng mixture on Wnt/β-catenin signaling pathway in the synovium inflamed by knee osteoarthritis: An in vitro and in vivo experiment.
Shi Q, Huang L, Duan J, Kuang G, Lu M, Tan X
Journal of ethnopharmacology 2022 Aug 10;294:115363
Journal of ethnopharmacology 2022 Aug 10;294:115363
Dematin inhibits glioblastoma malignancy through RhoA-mediated CDKs downregulation and cytoskeleton remodeling.
Wang M, Chen B, Zhang W, Zhang F, Qiu Y, Lin Y, Yang S
Experimental cell research 2022 Aug 1;417(1):113196
Experimental cell research 2022 Aug 1;417(1):113196
Elevated FAM84B promotes cell proliferation via interacting with NPM1 in esophageal squamous cell carcinoma.
Wang F, Cheng C, Wang X, Chen F, Li H, Zhou Y, Wang Y, Hu X, Kong P, Zhang L, Cheng X, Cui Y
Cell death discovery 2022 Apr 8;8(1):182
Cell death discovery 2022 Apr 8;8(1):182
Bolbostemma paniculatum (Maxim.) Franquet extract suppresses the development of colorectal cancer through downregulation of PI3K/Akt pathway.
Li Y, Sun Y, Zhang Q, Liu Y, Niu Y, Li X, Cai D
Journal of ethnopharmacology 2022 Apr 6;287:114937
Journal of ethnopharmacology 2022 Apr 6;287:114937
CYLD deficiency enhances metabolic reprogramming and tumor progression in nasopharyngeal carcinoma via PFKFB3.
Wang L, Lin Y, Zhou X, Chen Y, Li X, Luo W, Zhou Y, Cai L
Cancer letters 2022 Apr 28;532:215586
Cancer letters 2022 Apr 28;532:215586
β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway.
Nie Q, Peng WW, Wang Y, Zhong L, Zhang X, Zeng L
Gene 2022 Apr 15;818:146207
Gene 2022 Apr 15;818:146207
CDK5RAP3 acts as a putative tumor inhibitor in papillary thyroid carcinoma via modulation of Akt/GSK-3β/Wnt/β-catenin signaling.
Feng X, Jiang J, Sun L, Zhou Q
Toxicology and applied pharmacology 2022 Apr 1;440:115940
Toxicology and applied pharmacology 2022 Apr 1;440:115940
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Jin C, Ou Q, Chen J, Wang T, Zhang J, Wang Z, Wang Y, Tian H, Xu JY, Gao F, Wang J, Li J, Lu L, Xu GT
Stem cell research & therapy 2022 Apr 1;13(1):136
Stem cell research & therapy 2022 Apr 1;13(1):136
Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.
Lei X, Chen G, Li J, Wen W, Gong J, Fu J
PeerJ 2021;9:e12141
PeerJ 2021;9:e12141
Effect of Photodynamic Therapy on Gemcitabine-Resistant Cholangiocarcinoma in vitro and in vivo Through KLF10 and EGFR.
Yang Y, Li J, Yao L, Wu L
Frontiers in cell and developmental biology 2021;9:710721
Frontiers in cell and developmental biology 2021;9:710721
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
Dang NN, Li XB, Zhang M, Han C, Fan XY, Huang SH
Frontiers in cell and developmental biology 2021;9:662763
Frontiers in cell and developmental biology 2021;9:662763
NAP1L1 Functions as a Tumor Promoter via Recruiting Hepatoma-Derived Growth Factor/c-Jun Signal in Hepatocellular Carcinoma.
Zhang YW, Chen Q, Li B, Li HY, Zhao XK, Xiao YY, Liu S, Zuo S
Frontiers in cell and developmental biology 2021;9:659680
Frontiers in cell and developmental biology 2021;9:659680
CORO6 Promotes Cell Growth and Invasion of Clear Cell Renal Cell Carcinoma via Activation of WNT Signaling.
Wang X, Xiao Y, Li S, Yan Z, Luo G
Frontiers in cell and developmental biology 2021;9:647301
Frontiers in cell and developmental biology 2021;9:647301
LHPP-Mediated Histidine Dephosphorylation Suppresses the Self-Renewal of Mouse Embryonic Stem Cells.
Xia RM, Yao DB, Cai XM, Xu XQ
Frontiers in cell and developmental biology 2021;9:638815
Frontiers in cell and developmental biology 2021;9:638815
17β-Estradiol Inhibits Proliferation and Oxidative Stress in Vascular Smooth Muscle Cells by Upregulating BHLHE40 Expression.
Feng DD, Zheng B, Yu J, Zhang ML, Ma Y, Hao X, Wen JK, Zhang XH
Frontiers in cardiovascular medicine 2021;8:768662
Frontiers in cardiovascular medicine 2021;8:768662
Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.
Liu C, Chi K, Geng X, Hong Q, Mao Z, Huang Q, Liu D, Wang Y, Zhang Y, Zhou F, Cai G, Chen X, Sun X
Frontiers in medicine 2021;8:655787
Frontiers in medicine 2021;8:655787
Transcription Factors BARX1 and DLX4 Contribute to Progression of Clear Cell Renal Cell Carcinoma via Promoting Proliferation and Epithelial-Mesenchymal Transition.
Sun G, Ge Y, Zhang Y, Yan L, Wu X, Ouyang W, Wang Z, Ding B, Zhang Y, Long G, Liu M, Shi R, Zhou H, Chen Z, Ye Z
Frontiers in molecular biosciences 2021;8:626328
Frontiers in molecular biosciences 2021;8:626328
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, Qian W, Wang D, Yu D, Zhong C
Nutrition and cancer 2021;73(7):1157-1167
Nutrition and cancer 2021;73(7):1157-1167
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Zhang D, Li C, Zhang L, Li B, Wang Y, Wang R, Chen Z, Xu L, Liu T
Nutrition and cancer 2021;73(11-12):2491-2501
Nutrition and cancer 2021;73(11-12):2491-2501
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma.
Zhu L, Zheng Y, Hu R, Hu C
BioMed research international 2021;2021:5486131
BioMed research international 2021;2021:5486131
The Mechanism of miR-141 Regulating the Proliferation and Metastasis of Liver Cancer Cells by Targeting STAT4.
Ma L, Shao H, Chen H, Deng Q
Journal of oncology 2021;2021:5425491
Journal of oncology 2021;2021:5425491
Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma.
Zhang X, Xu X, Zhang Z, Xue C, Kong Z, Wu S, Yun X, Fu Y, Zhu C, Qin X
International journal of biological sciences 2021;17(3):768-780
International journal of biological sciences 2021;17(3):768-780
Increased Collagen Type V α2 (COL5A2) in Colorectal Cancer is Associated with Poor Prognosis and Tumor Progression.
Wang J, Jiang YH, Yang PY, Liu F
OncoTargets and therapy 2021;14:2991-3002
OncoTargets and therapy 2021;14:2991-3002
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
Zhang JJ, Song CG, Dai JM, Zhang XQ, Lin P, Li L, Yang XM, Chen ZN
American journal of translational research 2021;13(5):3967-3986
American journal of translational research 2021;13(5):3967-3986
A novel function for cyclin D1 as a transcriptional role in oncogenesis and tumor development by ChIP-Seq and RNA-Seq.
Xiong Y, Wang Y, Li T, Yu X, Zeng Y, Xiao G, Zhou F, Zhou Y
Journal of Cancer 2021;12(17):5181-5192
Journal of Cancer 2021;12(17):5181-5192
Lenvatinib induces anticancer activity in gallbladder cancer by targeting AKT.
Ye J, Qi L, Liang J, Zong K, Liu W, Li R, Feng R, Zhai W
Journal of Cancer 2021;12(12):3548-3557
Journal of Cancer 2021;12(12):3548-3557
Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder Cancer.
Zhang P, Yang Q
Frontiers in genetics 2021;12:682856
Frontiers in genetics 2021;12:682856
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Wang Y, Shen H, Sun Q, Zhao L, Liu H, Ye L, Xu Y, Cai J, Li Y, Gao L, Tan Y, Liu B, Chen Q
Frontiers in pharmacology 2021;12:659511
Frontiers in pharmacology 2021;12:659511
Therapeutic Potential of CUDC-907 (Fimepinostat) for Hepatocarcinoma Treatment Revealed by Tumor Spheroids-Based Drug Screening.
Liao W, Yang W, Xu J, Yan Z, Pan M, Xu X, Zhou S, Zhu Y, Lan J, Zeng M, Han X, Li S, Li Y, Liang K, Gao Y, Peng Q
Frontiers in pharmacology 2021;12:658197
Frontiers in pharmacology 2021;12:658197
Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for Treatment of Lung Adenocarcinoma.
Guo S, Bai X, Liu Y, Shi S, Wang X, Zhan Y, Kang X, Chen Y, An H
Frontiers in pharmacology 2021;12:643489
Frontiers in pharmacology 2021;12:643489
SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.
Jiang M, Kuang Z, He Y, Cao Y, Yu T, Cheng J, Liu W, Wang W
Frontiers in endocrinology 2021;12:624309
Frontiers in endocrinology 2021;12:624309
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Liu W, Zhan Z, Zhang M, Sun B, Shi Q, Luo F, Zhang M, Zhang W, Hou Y, Xiao X, Li Y, Feng H
Theranostics 2021;11(13):6278-6292
Theranostics 2021;11(13):6278-6292
Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer.
Wang D, Li Z, Yin H
Frontiers in oncology 2021;11:751903
Frontiers in oncology 2021;11:751903
tRNA-Derived Fragment tRF-Glu-TTC-027 Regulates the Progression of Gastric Carcinoma via MAPK Signaling Pathway.
Xu W, Zhou B, Wang J, Tang L, Hu Q, Wang J, Chen H, Zheng J, Yan F, Chen H
Frontiers in oncology 2021;11:733763
Frontiers in oncology 2021;11:733763
The lncRNA CASC2 Modulates Hepatocellular Carcinoma Cell Sensitivity and Resistance to TRAIL Through Apoptotic and Non-Apoptotic Signaling.
Sun J, Xu H, Lei Z, Li Z, Zhu H, Deng Z, Yu X, Jin X, Yang Z
Frontiers in oncology 2021;11:726622
Frontiers in oncology 2021;11:726622
Role of Notch pathway in effect of mono-2-ethylhexyl phthalate on the proliferation and cell cycle of SH-SY5Y cell.
Zhang B, Li X, Zhang X, Ye J, Zhao W, Zhang M, Xing J, Qi W, Ye L
Environmental toxicology 2021 Sep;36(9):1944-1952
Environmental toxicology 2021 Sep;36(9):1944-1952
TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.
Zhu G, Herlyn M, Yang X
Nature cell biology 2021 Sep;23(9):978-991
Nature cell biology 2021 Sep;23(9):978-991
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
Bai ZM, Li XF, Yang Y, Yang YF, Lv DR, Tang LL
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma.
Wang B, Yin X, Gan W, Pan F, Li S, Xiang Z, Han X, Li D
Autophagy 2021 Sep;17(9):2475-2493
Autophagy 2021 Sep;17(9):2475-2493
The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy.
Liu H, Wei J, Sang N, Zhong X, Zhou X, Yang X, Zhang J, Zuo Z, Zhou Y, Yang S, Du J, Zhao Y
Medical oncology (Northwood, London, England) 2021 Sep 7;38(10):124
Medical oncology (Northwood, London, England) 2021 Sep 7;38(10):124
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
Zeng S, Chen L, Sun Q, Zhao H, Yang H, Ren S, Liu M, Meng X, Xu H
European journal of pharmacology 2021 Sep 5;906:174253
European journal of pharmacology 2021 Sep 5;906:174253
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.
Zhang YL, Chen GL, Liu Y, Zhuang XC, Guo MQ
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Bromodomain-containing protein 9 promotes hepatocellular carcinoma progression via activating the Wnt/β-catenin signaling pathway.
Fang D, Wang MR, Guan JL, Han YY, Sheng JQ, Tian DA, Li PY
Experimental cell research 2021 Sep 15;406(2):112727
Experimental cell research 2021 Sep 15;406(2):112727
LncAY controls BMI1 expression and activates BMI1/Wnt/β-catenin signaling axis in hepatocellular carcinoma.
Chen MH, Fu LS, Zhang F, Yang Y, Wu XZ
Life sciences 2021 Sep 1;280:119748
Life sciences 2021 Sep 1;280:119748
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
Huang L, Zhang H, Zhao D, Hu H, Lu Z
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Zhou C, Liang Y, Zhou L, Yan Y, Liu N, Zhang R, Huang Y, Wang M, Tang Y, Ali DW, Wang Y, Michalak M, Chen XZ, Tang J
Autophagy 2021 Oct;17(10):3175-3195
Autophagy 2021 Oct;17(10):3175-3195
Silent information regulator 2 promotes clear cell renal cell carcinoma progression through deacetylation and small ubiquitin-related modifier 1 modification of glucose 6-phosphate dehydrogenase.
Ni Y, Yang Z, Agbana YL, Bai H, Wang L, Yang L, Yi Z, Cheng J, Zhang Q, Kuang Y, Zhu Y
Cancer science 2021 Oct;112(10):4075-4086
Cancer science 2021 Oct;112(10):4075-4086
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Zhang J, Zou L, Shi D, Liu J, Zhang J, Zhao R, Wang G, Zhang L, Ouyang L, Liu B
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Wang S, Xu X, Che D, Fan R, Gao M, Cao Y, Ge C, Feng Y, Li J, Xie S, Wang C, Dai F, Gao L, Wang Y
International journal of molecular sciences 2021 Oct 12;22(20)
International journal of molecular sciences 2021 Oct 12;22(20)
TMEM16A, a Homoharringtonine Receptor, as a Potential Endogenic Target for Lung Cancer Treatment.
Guo S, Bai X, Shi S, Deng Y, Kang X, An H
International journal of molecular sciences 2021 Oct 10;22(20)
International journal of molecular sciences 2021 Oct 10;22(20)
Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration.
Song AN, Yin XJ, Gao P, Tang H, Meng XF, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21959
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21959
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Chen W, Zhao S, Yu W, Rao T, Ruan Y, Zhu S, Xia Y, Song H, Cheng F
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer.
Tay DJT, Song Y, Peng B, Toh TB, Hooi L, Toh DK, Hong H, Tang SJ, Han J, Gan WL, Chan THM, Krishna MS, Patil KM, Maraswami M, Loh TP, Dan YY, Zhou L, Bonney GK, Chow PK, Chen G, Chow EK, Le MTN, Chen L
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Nov 3;29(11):3258-3273
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Nov 3;29(11):3258-3273
Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness.
Xie X, Chen J, Wo D, Ma E, Ning Y, Peng J, Zhu W, Ren DN
Journal of ethnopharmacology 2021 Nov 15;280:114449
Journal of ethnopharmacology 2021 Nov 15;280:114449
Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/β-catenin pathway in hepatocellular carcinoma.
Liu X, Shan W, Li T, Gao X, Kong F, You H, Kong D, Qiao S, Tang R
BMC cancer 2021 Nov 14;21(1):1224
BMC cancer 2021 Nov 14;21(1):1224
NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth.
Liu S, Zhang Y, Cui S, Song D, Li B, Chen Q, Yao G, Gong B
Cancer cell international 2021 Nov 13;21(1):605
Cancer cell international 2021 Nov 13;21(1):605
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Li C, Li L, Ali I, Kuang M, Wang X, Wang G
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways.
Kong L, Yu Y, Guan H, Jiang L, Sun F, Li X, Huang W, Li B
International journal of molecular medicine 2021 May;47(5)
International journal of molecular medicine 2021 May;47(5)
Niacin stimulates EPH4EV mammary epithelial cell proliferation and mammary gland development in pubertal mice through activation of AKT/mTOR and ERK1/2 signaling pathways.
Cao Y, Zhang Y, Ma L, Wang J, Guo W, Cheng J, Hu G, Fu S, Liu J
Cell and tissue research 2021 May;384(2):313-324
Cell and tissue research 2021 May;384(2):313-324
Expression of COX-2 and Nrf2/GPx3 in the anterior vaginal wall tissues of women with pelvic organ prolapse.
Lin T, Ji Y, Zhao Y, Xia Z
Archives of gynecology and obstetrics 2021 May;303(5):1245-1253
Archives of gynecology and obstetrics 2021 May;303(5):1245-1253
Pyrvinium pamoate can overcome artemisinin's resistance in anaplastic thyroid cancer.
Li Y
BMC complementary medicine and therapies 2021 May 28;21(1):156
BMC complementary medicine and therapies 2021 May 28;21(1):156
Activity Components from Gynostemma pentaphyllum for Preventing Hepatic Fibrosis and of Its Molecular Targets by Network Pharmacology Approach.
Zhang Y, Shi G, Luo Z, Wang J, Wu S, Zhang X, Zhao Y
Molecules (Basel, Switzerland) 2021 May 18;26(10)
Molecules (Basel, Switzerland) 2021 May 18;26(10)
CUX1 Enhances Pancreatic Cancer Formation by Synergizing with KRAS and Inducing MEK/ERK-Dependent Proliferation.
Griesmann H, Mühl S, Riedel J, Theuerkorn K, Sipos B, Esposito I, Vanden Heuvel GB, Michl P
Cancers 2021 May 18;13(10)
Cancers 2021 May 18;13(10)
Long intergenic non-coding RNA 00473 promotes proliferation and migration of gastric cancer via the miR-16-5p/CCND2 axis and by regulating AQP3.
Zhuo S, Sun M, Bai R, Lu D, Di S, Ma T, Zou Z, Li H, Zhang Z
Cell death & disease 2021 May 15;12(5):496
Cell death & disease 2021 May 15;12(5):496
Nucleolar and spindle‑associated protein 1 promotes non‑small cell lung cancer progression and serves as an effector of myocyte enhancer factor 2D.
Ling B, Wei P, Xiao J, Cen B, Wei H, Feng X, Ye G, Li S, Zhang Z, Liang W, Huang S, Huang W
Oncology reports 2021 Mar;45(3):1044-1058
Oncology reports 2021 Mar;45(3):1044-1058
Down-regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p.
Wu J, Li Y, Liu J, Xu Y
The journal of gene medicine 2021 Mar;23(3):e3293
The journal of gene medicine 2021 Mar;23(3):e3293
LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis.
Zhu C, He X, Chen K, Huang Z, Yao A, Tian X, You Y, Zeng M
Cell cycle (Georgetown, Tex.) 2021 Mar-Mar;20(5-6):575-590
Cell cycle (Georgetown, Tex.) 2021 Mar-Mar;20(5-6):575-590
miRNA in food simultaneously controls animal viral disease and human tumorigenesis.
Cui Y, Wan H, Zhang X
Molecular therapy. Nucleic acids 2021 Mar 5;23:995-1006
Molecular therapy. Nucleic acids 2021 Mar 5;23:995-1006
The influence of phenolic environmental estrogen on the transcriptome of uterine leiomyoma cells: A whole transcriptome profiling-based analysis.
Li Z, Yin H, Shen Y, Ren M, Xu X
Ecotoxicology and environmental safety 2021 Mar 15;211:111945
Ecotoxicology and environmental safety 2021 Mar 15;211:111945
FoxP3-miR-150-5p/3p suppresses ovarian tumorigenesis via an IGF1R/IRS1 pathway feedback loop.
Zhang Q, Zhou X, Wan M, Zeng X, Luo J, Xu Y, Ji L, Zhang JA, Fan P, Zhong J, Wu J
Cell death & disease 2021 Mar 15;12(3):275
Cell death & disease 2021 Mar 15;12(3):275
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Wang F, Younis M, Luo Y, Zhang L, Yuan L
International immunopharmacology 2021 Jun;95:107532
International immunopharmacology 2021 Jun;95:107532
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Jia R, Yang F, Yan P, Ma L, Yang L, Li L
Free radical biology & medicine 2021 Jun;169:158-168
Free radical biology & medicine 2021 Jun;169:158-168
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Luo X, Cao M, Gao F, He X
Experimental hematology & oncology 2021 Jun 4;10(1):35
Experimental hematology & oncology 2021 Jun 4;10(1):35
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Jiao X, Wang B, Feng C, Song S, Tian B, Zhou C, Gao X, Sun W, Liu P
BMC cancer 2021 Jun 30;21(1):760
BMC cancer 2021 Jun 30;21(1):760
MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway.
Wang Y, Zheng Y, Chen Q, Dai Y, Li T
Archives of biochemistry and biophysics 2021 Jun 15;704:108719
Archives of biochemistry and biophysics 2021 Jun 15;704:108719
CENPE contributes to pulmonary vascular remodeling in pulmonary hypertension.
Fang X, Xie M, Liu X, He Y
Biochemical and biophysical research communications 2021 Jun 11;557:40-47
Biochemical and biophysical research communications 2021 Jun 11;557:40-47
ND‑09 inhibits chronic myeloid leukemia K562 cell growth by regulating BCR‑ABL signaling.
Liu YH, Zhu M, Lei PP, Pan XY, Ma WN
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
Effect of fenofibrate on proliferation of SMMC-7721 cells via regulating cell cycle.
Li B, Jiang HY, Wang ZH, Ma YC, Bao YN, Jin Y
Human & experimental toxicology 2021 Jul;40(7):1208-1221
Human & experimental toxicology 2021 Jul;40(7):1208-1221
METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
Wang XK, Zhang YW, Wang CM, Li B, Zhang TZ, Zhou WJ, Cheng LJ, Huo MY, Zhang CH, He YL
Journal of cellular and molecular medicine 2021 Jul;25(14):6602-6617
Journal of cellular and molecular medicine 2021 Jul;25(14):6602-6617
BACH1 is transcriptionally inhibited by TET1 in hepatocellular carcinoma in a microRNA-34a-dependent manner to regulate autophagy and inflammation.
Sun X, Zhu H, Cao R, Zhang J, Wang X
Pharmacological research 2021 Jul;169:105611
Pharmacological research 2021 Jul;169:105611
miRNA-194 predicts favorable prognosis in gastric cancer and inhibits gastric cancer cell growth by targeting CCND1.
Wang J, Zhang M, Hu X, She J, Sun R, Qin S, Li D
FEBS open bio 2021 Jul;11(7):1814-1826
FEBS open bio 2021 Jul;11(7):1814-1826
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
Luo P, He WX, Li C, Chang MJ
Neuroreport 2021 Jul 7;32(10):875-881
Neuroreport 2021 Jul 7;32(10):875-881
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Li H, Dang C, Tai X, Xue L, Meng Y, Ma S, Zhang J
Scientific reports 2021 Jul 22;11(1):14985
Scientific reports 2021 Jul 22;11(1):14985
Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis.
Yang B, Li L, Tong G, Zeng Z, Tan J, Su Z, Liu Z, Lin J, Gao W, Chen J, Zeng S, Wu G, Li L, Zhu S, Liu Q, Lin L
Journal of experimental & clinical cancer research : CR 2021 Jul 16;40(1):235
Journal of experimental & clinical cancer research : CR 2021 Jul 16;40(1):235
Circular RNA-DPP4 serves an oncogenic role in prostate cancer progression through regulating miR-195/cyclin D1 axis.
Yang D, Yang B, Zhu Y, Xia Q, Zhang Y, Zhu X, Guo J, Ding T, Zheng J
Cancer cell international 2021 Jul 16;21(1):379
Cancer cell international 2021 Jul 16;21(1):379
Long noncoding RNA GAS5 accelerates diabetic wound healing and promotes lymphangiogenesis via miR-217/Prox1 axis.
He ZY, Huang MT, Cui X, Zhou ST, Wu Y, Zhang PH, Zhou J
Molecular and cellular endocrinology 2021 Jul 15;532:111283
Molecular and cellular endocrinology 2021 Jul 15;532:111283
Maternally expressed 3 protects the intestinal barrier from cardiac arrest-induced ischemia/reperfusion injury via miR-34a-3p/sirtuin 1/nuclear factor kappa B signaling.
Huang X, Pan M, Du P, Chen Y, Zhang C, Lu W, Lin J
Annals of translational medicine 2021 Jan;9(2):122
Annals of translational medicine 2021 Jan;9(2):122
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
Jiang F, Ren S, Chen Y, Zhang A, Zhu Y, Zhang Z, Li Z, Piao D
Oncology reports 2021 Jan;45(1):139-150
Oncology reports 2021 Jan;45(1):139-150
Absence of the MFG-E8 gene prevents hypoxia-induced pulmonary hypertension in mice.
Wang J, Wu J, Zhu X, Chen J, Zhao J, Xu Y, Xie J
Journal of cellular physiology 2021 Jan;236(1):587-600
Journal of cellular physiology 2021 Jan;236(1):587-600
The circular RNA circZFR phosphorylates Rb promoting cervical cancer progression by regulating the SSBP1/CDK2/cyclin E1 complex.
Zhou M, Yang Z, Wang D, Chen P, Zhang Y
Journal of experimental & clinical cancer research : CR 2021 Jan 30;40(1):48
Journal of experimental & clinical cancer research : CR 2021 Jan 30;40(1):48
Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma.
Ma J, Chen X, Lin M, Wang Z, Wu Y, Li J
Cancer cell international 2021 Jan 21;21(1):65
Cancer cell international 2021 Jan 21;21(1):65
Knockdown of CENPF inhibits the progression of lung adenocarcinoma mediated by ERβ2/5 pathway.
Hexiao T, Yuquan B, Lecai X, Yanhong W, Li S, Weidong H, Ming X, Xuefeng Z, Gaofeng P, Li Z, Minglin Z, Zheng T, Zetian Y, Xiao Z, Yi C, Lanuti M, Jinping Z
Aging 2021 Jan 10;13(2):2604-2625
Aging 2021 Jan 10;13(2):2604-2625
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Liu S, Gong Y, Xu XD, Shen H, Gao S, Bao HD, Guo SB, Yu XF, Gong J
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
Sericin inhibits MDA‑MB‑468 cell proliferation via the PI3K/Akt pathway in triple‑negative breast cancer.
Niu L, Yang S, Zhao X, Liu X, Si L, Wei M, Liu L, Cheng L, Qiao Y, Chen Z
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Wang J, Hu X, Hu X, Gao F, Li M, Cui Y, Wei X, Qin Y, Zhang C, Zhao Y, Gao Y
The international journal of biochemistry & cell biology 2021 Feb;131:105873
The international journal of biochemistry & cell biology 2021 Feb;131:105873
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Fan H, Xin T, Dong X, Yang F, Zhang R, Feng S, He D, Guo H, Pang Q
Experimental and molecular pathology 2021 Feb;118:104571
Experimental and molecular pathology 2021 Feb;118:104571
Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
Qin J, Qu S, Zhu K, Cheng Y, Pan G, Jing W, Liu X, Sun X, Liu L
Bioorganic & medicinal chemistry 2021 Feb 15;32:116003
Bioorganic & medicinal chemistry 2021 Feb 15;32:116003
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Liu S, Chen L, Chen H, Xu K, Peng X, Zhang M
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
Feng S, Liu H, Du P, Dong X, Pang Q, Guo H
Annals of translational medicine 2021 Dec;9(23):1729
Annals of translational medicine 2021 Dec;9(23):1729
Synergistic inhibitory effect of Smo inhibitor jervine and its combination with decitabine can target Hedgehog signaling pathway to inhibit myelodysplastic syndrome cell line.
Zhao F, Wang J, Yao L, Qin YT, Tuerxun N, Wang H, Jiang M, Hao JP
Hematology (Amsterdam, Netherlands) 2021 Dec;26(1):518-528
Hematology (Amsterdam, Netherlands) 2021 Dec;26(1):518-528
Cell division cycle associated 8: A novel diagnostic and prognostic biomarker for hepatocellular carcinoma.
Cui XH, Peng QJ, Li RZ, Lyu XJ, Zhu CF, Qin XH
Journal of cellular and molecular medicine 2021 Dec;25(24):11097-11112
Journal of cellular and molecular medicine 2021 Dec;25(24):11097-11112
The protective mechanism of Klotho gene-modified bone marrow mesenchymal stem cells on acute kidney injury induced by rhabdomyolysis.
Ni W, Zhang Y, Yin Z
Regenerative therapy 2021 Dec;18:255-267
Regenerative therapy 2021 Dec;18:255-267
S100A11 regulates nasal epithelial cell remodeling and inflammation in CRSwNPs via the RAGE-mediated AMPK-STAT3 pathway.
Liu C, Du H, Wang Y, Gong N, Qi W, Zhou X, Shi L
Molecular immunology 2021 Dec;140:35-46
Molecular immunology 2021 Dec;140:35-46
Senescence marker protein 30 inhibits tumor growth by reducing HDAC4 expression in non-small cell lung cancer.
Shao C, Guo K, Xu L, Zhang Y, Duan H, Feng Y, Pan M, Lu D, Ren X, Ganti AK, Hakozaki T, Han J, Yan X, Ma Z
Translational lung cancer research 2021 Dec;10(12):4558-4573
Translational lung cancer research 2021 Dec;10(12):4558-4573
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
Chen C, Wang YS, Zhang ET, Li GA, Liu WY, Li Y, Jin YH
International journal of molecular sciences 2021 Dec 6;22(23)
International journal of molecular sciences 2021 Dec 6;22(23)
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
Gong X, Tian M, Cao N, Yang P, Xu Z, Zheng S, Liao Q, Chen C, Zeng C, Jose PA, Wang DZ, Jian Z, Xiao Y, Jiang DS, Wei X, Zhang B, Wang Y, Chen K, Wu G, Zeng C
The Journal of clinical investigation 2021 Dec 15;131(24)
The Journal of clinical investigation 2021 Dec 15;131(24)
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
Cheng Y, Hu Y, Wang H, Zhao Z, Jiang X, Zhang Y, Zhang J, Tong Y, Qiu X
Journal of cellular and molecular medicine 2021 Aug;25(16):7796-7808
Journal of cellular and molecular medicine 2021 Aug;25(16):7796-7808
Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell.
Chang L, Zhou R, He Y, Meng M, Hu J, Liu Y, Pan Y, Tang Z, Yue Z
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
SETD4 in the Proliferation, Migration, Angiogenesis, Myogenic Differentiation and Genomic Methylation of Bone Marrow Mesenchymal Stem Cells.
Liao X, Wu C, Shao Z, Zhang S, Zou Y, Wang K, Ha Y, Xing J, Zheng A, Shen Z, Zheng S, Guo J, Jie W
Stem cell reviews and reports 2021 Aug;17(4):1374-1389
Stem cell reviews and reports 2021 Aug;17(4):1374-1389
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
Zhang X, Shi X, Wang J, Xu Z, He J
Aging 2021 Aug 30;13(16):20748-20761
Aging 2021 Aug 30;13(16):20748-20761
LncRNA LINC00680 promotes lung adenocarcinoma growth via binding to GATA6 and canceling GATA6-mediated suppression of SOX12 expression.
Sun X, Wang R, Tan M, Tian X, Meng J
Experimental cell research 2021 Aug 1;405(1):112653
Experimental cell research 2021 Aug 1;405(1):112653
Hybrid-cell membrane-coated nanocomplex-loaded chikusetsusaponin IVa methyl ester for a combinational therapy against breast cancer assisted by Ce6.
Xie Q, Liu Y, Long Y, Wang Z, Jiang S, Ahmed R, Daniyal M, Li B, Liu B, Wang W
Biomaterials science 2021 Apr 21;9(8):2991-3004
Biomaterials science 2021 Apr 21;9(8):2991-3004
SIRT4 is the molecular switch mediating cellular proliferation in colorectal cancer through GLS mediated activation of AKT/GSK3β/CyclinD1 pathway.
Cui Y, Bai Y, Yang J, Yao Y, Zhang C, Liu C, Shi J, Li Q, Zhang J, Lu X, Zhang Y
Carcinogenesis 2021 Apr 17;42(3):481-492
Carcinogenesis 2021 Apr 17;42(3):481-492
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
Sheng J, He X, Yu W, Chen Y, Long Y, Wang K, Zhu S, Liu Q
Cancer letters 2021 Apr 10;503:54-68
Cancer letters 2021 Apr 10;503:54-68
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
Yuan C, Yang D, Ma J, Yang J, Xue J, Song F, Liu X
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
THAP11 Functions as a Tumor Suppressor in Gastric Cancer through Regulating c-Myc Signaling Pathways.
Zhang J, Zhang H, Shi H, Wang F, Du J, Wang Y, Wei Y, Xue W, Li D, Feng Y, Yan J, Gao Y, Li J, Han J
BioMed research international 2020;2020:7838924
BioMed research international 2020;2020:7838924
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
Mao Y, Li W, Hua B, Gu X, Pan W, Chen Q, Xu B, Wang Z, Lu C
BioMed research international 2020;2020:2406159
BioMed research international 2020;2020:2406159
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
Zhang R, Liu J, Zhang W, Hua L, Qian LT, Zhou SB
Cancer cell international 2020;20:20
Cancer cell international 2020;20:20
Cancer Cell enters reversible quiescence through Intracellular Acidification to resist Paclitaxel Cytotoxicity.
Jia M, Zheng D, Wang X, Zhang Y, Chen S, Cai X, Mo L, Hu Z, Li H, Zhou Z, Li J
International journal of medical sciences 2020;17(11):1652-1664
International journal of medical sciences 2020;17(11):1652-1664
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
Song D, Xu B, Shi D, Li S, Cai Y
Open medicine (Warsaw, Poland) 2020;15(1):317-326
Open medicine (Warsaw, Poland) 2020;15(1):317-326
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Zhang X, Luo Y, Li Q
OncoTargets and therapy 2020;13:5819-5830
OncoTargets and therapy 2020;13:5819-5830
Derlin-1 Promotes the Progression of Human Hepatocellular Carcinoma via the Activation of AKT Pathway.
Fan J, Tian L, Huang S, Zhang J, Zhao B
OncoTargets and therapy 2020;13:5407-5417
OncoTargets and therapy 2020;13:5407-5417
Up-Regulated CCDC34 Contributes to the Proliferation and Metastasis of Hepatocellular Carcinoma.
Lin Z, Qu S, Peng W, Yang P, Zhang R, Zhang P, Guo D, Du J, Wu W, Tao K, Wang J
OncoTargets and therapy 2020;13:51-60
OncoTargets and therapy 2020;13:51-60
ΔNp63α promotes the expression and nuclear translocation of PTEN, leading to cisplatin resistance in oral cancer cells.
Hao T, Gan YH
American journal of translational research 2020;12(10):6187-6203
American journal of translational research 2020;12(10):6187-6203
Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.
Jing X, Chen Y, Chen Y, Shi G, Lv S, Cheng N, Feng C, Xin Z, Zhang L, Wu J
Cancer management and research 2020;12:2185-2194
Cancer management and research 2020;12:2185-2194
AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.
Xu F, Xu Y, Xiong JH, Zhang JH, Wu J, Luo J, Xiong JP
Cancer management and research 2020;12:1789-1798
Cancer management and research 2020;12:1789-1798
Activated STAT3 Could Reduce Survival in Patients with Esophageal Squamous Cell Carcinoma by Up-regulating VEGF and Cyclin D1 Expression.
Zhang N, Zhang M, Wang Z, Gao W, Sun ZG
Journal of Cancer 2020;11(7):1859-1868
Journal of Cancer 2020;11(7):1859-1868
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ren Y, Wang Y, Hao S, Yang Y, Xiong W, Qiu L, Tao J, Tang A
Journal of Cancer 2020;11(23):6939-6949
Journal of Cancer 2020;11(23):6939-6949
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1.
Yang M, Hu C, Cao Y, Liang W, Yang X, Xiao T
Frontiers in pharmacology 2020;11:622212
Frontiers in pharmacology 2020;11:622212
AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway.
Gao L, Liu J, Xu P, Deng G, Liu B, Yuan F, Tan Y, Sun Q, Xu Y, Zhang H, Qi Y, Han S, Yang K, Geng R, Jiang H, Chen Q
Frontiers in pharmacology 2020;11:1102
Frontiers in pharmacology 2020;11:1102
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Meng F, Liu X, Lin C, Xu L, Liu J, Zhang P, Zhang X, Song J, Yan Y, Ren Z, Zhang Y
American journal of cancer research 2020;10(3):997-1011
American journal of cancer research 2020;10(3):997-1011
GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.
Cheng L, Gou L, Wei T, Zhang J
International journal of oncology 2020 Sep;57(3):858-870
International journal of oncology 2020 Sep;57(3):858-870
Aristolochic acid induces renal fibrosis by arresting proximal tubular cells in G2/M phase mediated by HIF-1α.
Zhao H, Jiang N, Han Y, Yang M, Gao P, Xiong X, Xiong S, Zeng L, Xiao Y, Wei L, Li L, Li C, Yang J, Tang C, Xiao L, Liu F, Liu Y, Sun L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12599-12614
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12599-12614
PAK6 promotes cervical cancer progression through activation of the Wnt/β-catenin signaling pathway.
Yang Q, Zhao Y, Chen Y, Chang Y, Huang A, Xu T, Li G, Wu G
Oncology letters 2020 Sep;20(3):2387-2395
Oncology letters 2020 Sep;20(3):2387-2395
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
Liu J, Shangguan Y, Sun J, Cong W, Xie Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
UBAC2 promotes bladder cancer proliferation through BCRC-3/miRNA-182-5p/p27 axis.
Gu C, Zhao K, Zhou N, Liu F, Xie F, Yu S, Feng Y, Chen L, Yang J, Tian F, Jiang G
Cell death & disease 2020 Sep 10;11(9):733
Cell death & disease 2020 Sep 10;11(9):733
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
Yu G, Liu P, Shi Y, Li S, Liu Y, Fan Z, Zhu W
Journal of neurosurgery 2020 Sep 1;133(3):918-926
Journal of neurosurgery 2020 Sep 1;133(3):918-926
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
Wang L, Xu X, Liu T, Wang J, Shen J, Guo M, Wu Y, Zhai X, Zuo D
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
Matic S, D'Souza DH, Wu T, Pangloli P, Dia VP
Immunological investigations 2020 Oct;49(7):711-725
Immunological investigations 2020 Oct;49(7):711-725
miR‑483‑3p promotes the osteogenesis of human osteoblasts by targeting Dikkopf 2 (DKK2) and the Wnt signaling pathway.
Zhou B, Peng K, Wang G, Chen W, Liu P, Chen F, Kang Y
International journal of molecular medicine 2020 Oct;46(4):1571-1581
International journal of molecular medicine 2020 Oct;46(4):1571-1581
Oncogenic gene RGC-32 is a direct target of miR-26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling.
Yang ZH, Li J, Chen WZ, Kong FS
Cell biochemistry and function 2020 Oct;38(7):943-954
Cell biochemistry and function 2020 Oct;38(7):943-954
Melatonin synergizes BRAF-targeting agent dabrafenib for the treatment of anaplastic thyroid cancer by inhibiting AKT/hTERT signalling.
Liao Y, Gao Y, Chang A, Li Z, Wang H, Cao J, Gu W, Tang R
Journal of cellular and molecular medicine 2020 Oct;24(20):12119-12130
Journal of cellular and molecular medicine 2020 Oct;24(20):12119-12130
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Feng AL, Han X, Meng X, Chen Z, Li Q, Shu W, Dai H, Zhu J, Yang Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells.
Wu Z, Zhan Y, Wang L, Tong J, Zhang L, Lin M, Jin X, Jiang L, Lou Y, Qiu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110556
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110556
PRMT5/Wnt4 axis promotes lymph-node metastasis and proliferation of laryngeal carcinoma.
Wang N, Yan H, Wu D, Zhao Z, Chen X, Long Q, Zhang C, Wang X, Deng W, Liu X
Cell death & disease 2020 Oct 15;11(10):864
Cell death & disease 2020 Oct 15;11(10):864
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26.
Jin C, Li Y, Su Y, Guo Z, Wang X, Wang S, Zhang F, Zhang Z, Shao J, Zheng S
Cell death & disease 2020 Oct 11;11(10):844
Cell death & disease 2020 Oct 11;11(10):844
Mitochondrial UQCC3 Modulates Hypoxia Adaptation by Orchestrating OXPHOS and Glycolysis in Hepatocellular Carcinoma.
Yang Y, Zhang G, Guo F, Li Q, Luo H, Shu Y, Shen Y, Gan J, Xu L, Yang H
Cell reports 2020 Nov 3;33(5):108340
Cell reports 2020 Nov 3;33(5):108340
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Zhang Y, Liu X, Yu M, Xu M, Xiao Y, Ma W, Huang L, Li X, Ye X
Life sciences 2020 Nov 1;260:118413
Life sciences 2020 Nov 1;260:118413
Metformin suppresses proliferation and invasion of drug-resistant breast cancer cells by activation of the Hippo pathway.
Liu J, Li J, Chen H, Wang R, Li P, Miao Y, Liu P
Journal of cellular and molecular medicine 2020 May;24(10):5786-5796
Journal of cellular and molecular medicine 2020 May;24(10):5786-5796
Kp-10 promotes bovine mammary epithelial cell proliferation by activating GPR54 and its downstream signaling pathways.
Li Y, Cao Y, Wang J, Fu S, Cheng J, Ma L, Zhang Q, Guo W, Kan X, Liu J
Journal of cellular physiology 2020 May;235(5):4481-4493
Journal of cellular physiology 2020 May;235(5):4481-4493
MS-275 combined with cisplatin exerts synergistic antitumor effects in human esophageal squamous cell carcinoma cells.
Liu T, Guan F, Wang Y, Zhang Z, Li Y, Cui Y, Li Z, Liu H, Zhang Y, Wang Y, Ma S
Toxicology and applied pharmacology 2020 May 15;395:114971
Toxicology and applied pharmacology 2020 May 15;395:114971
MiR-193b-5p inhibits proliferation and enhances radio-sensitivity by downregulating the AKT/mTOR signaling pathway in tongue cancer.
Jiang L, He C, Zhang X, Chen Y, Li G
Translational cancer research 2020 Mar;9(3):1851-1860
Translational cancer research 2020 Mar;9(3):1851-1860
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Li K, Zhang J, Tian Y, He Y, Xu X, Pan W, Gao Y, Chen F, Wei L
Oncogene 2020 Mar;39(11):2258-2274
Oncogene 2020 Mar;39(11):2258-2274
Increased expression of hematological and neurological expressed 1 (HN1) is associated with a poor prognosis of hepatocellular carcinoma and its knockdown inhibits cell growth and migration partly by down-regulation of c-Met.
Chen JJ, Sun X, Mao QQ, Jiang XY, Zhao XG, Xu WJ, Zhong L
The Kaohsiung journal of medical sciences 2020 Mar;36(3):196-205
The Kaohsiung journal of medical sciences 2020 Mar;36(3):196-205
Ablation of Gsa impairs renal tubule proliferation after injury via CDK2/cyclin E.
Liu L, Deng Y, Cai Y, Lu P, Guo Y, Zhang C, Li Q, Zhang T, Han M, Xu G
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F793-F803
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F793-F803
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Pan H, Liu F, Wang J, Zhao M, Wang D, Jia C, Wang T, Chen Z, Fan Y, Liang D, Meng Q
Molecular carcinogenesis 2020 Jun;59(6):575-589
Molecular carcinogenesis 2020 Jun;59(6):575-589
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
Peng F, Li G, Xie Y, Yin HY, Li XJ, Yang YD
Journal of food biochemistry 2020 Jun;44(6):e13222
Journal of food biochemistry 2020 Jun;44(6):e13222
ASH2L is involved in promotion of endometrial cancer progression via upregulation of PAX2 transcription.
Zeng K, Wu Y, Wang C, Wang S, Sun H, Zou R, Sun G, Song H, Liu W, Sun N, Wei S, Liu W, Su Y, Zhou T, Zhang Y, Zhao Y
Cancer science 2020 Jun;111(6):2062-2077
Cancer science 2020 Jun;111(6):2062-2077
Radiation-Induced DNMT3B Promotes Radioresistance in Nasopharyngeal Carcinoma through Methylation of p53 and p21.
Wu C, Guo E, Ming J, Sun W, Nie X, Sun L, Peng S, Luo M, Liu D, Zhang L, Mei Q, Long G, Hu G, Hu G
Molecular therapy oncolytics 2020 Jun 26;17:306-319
Molecular therapy oncolytics 2020 Jun 26;17:306-319
HnRNP A1 - mediated alternative splicing of CCDC50 contributes to cancer progression of clear cell renal cell carcinoma via ZNF395.
Sun G, Zhou H, Chen K, Zeng J, Zhang Y, Yan L, Yao W, Hu J, Wang T, Xing J, Xiao K, Wu L, Ye Z, Xu H
Journal of experimental & clinical cancer research : CR 2020 Jun 19;39(1):116
Journal of experimental & clinical cancer research : CR 2020 Jun 19;39(1):116
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196
International journal of oncology 2020 Jul;57(1):183-196
miR‑96 exerts an oncogenic role in the progression of cervical cancer by targeting CAV‑1.
Chen Y, Liu C, Xie B, Chen S, Zhuang Y, Zhang S
Molecular medicine reports 2020 Jul;22(1):543-550
Molecular medicine reports 2020 Jul;22(1):543-550
Garcinol acts as an antineoplastic agent in human gastric cancer by inhibiting the PI3K/AKT signaling pathway.
Zheng Y, Guo C, Zhang X, Wang X, Ma A
Oncology letters 2020 Jul;20(1):667-676
Oncology letters 2020 Jul;20(1):667-676
PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells.
Chen J, Yang HM, Zhou HC, Peng RR, Niu ZX, Kang CY
Oncology letters 2020 Jul;20(1):639-646
Oncology letters 2020 Jul;20(1):639-646
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J
Molecular cancer 2020 Jul 29;19(1):118
Molecular cancer 2020 Jul 29;19(1):118
The interaction of tumor cells and myeloid-derived suppressor cells in chronic myelogenous leukemia.
Xu H, Liu J, Shen N, Zhao Z, Cui J, Zhou S, Jiang L, Zhu X, Tang L, Liang H, Liu W, Zhu Z, Meng L, Zhu X
Leukemia & lymphoma 2020 Jan;61(1):128-137
Leukemia & lymphoma 2020 Jan;61(1):128-137
Transcription factor E2F4 is a positive regulator of milk biosynthesis and proliferation of bovine mammary epithelial cells.
Zhen Z, Zhang M, Yuan X, Li M
Cell biology international 2020 Jan;44(1):229-241
Cell biology international 2020 Jan;44(1):229-241
Par6 regulates cell cycle progression through enhancement of Akt/PI3K/GSK-3β signaling pathway activation in glioma.
Liu P, Zhu C, Luo J, Lan S, Su D, Wang Q, Wei Z, Cui W, Xu C, Yang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1481-1496
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1481-1496
LINC00511 contributes to glioblastoma tumorigenesis and epithelial-mesenchymal transition via LINC00511/miR-524-5p/YB1/ZEB1 positive feedback loop.
Du X, Tu Y, Liu S, Zhao P, Bao Z, Li C, Li J, Pan M, Ji J
Journal of cellular and molecular medicine 2020 Jan;24(2):1474-1487
Journal of cellular and molecular medicine 2020 Jan;24(2):1474-1487
SOX6 suppresses the development of lung adenocarcinoma by regulating expression of p53, p21(CIPI) , cyclin D1 and β-catenin.
Lv L, Zhou M, Zhang J, Liu F, Qi L, Zhang S, Bi Y, Yu Y
FEBS open bio 2020 Jan;10(1):135-146
FEBS open bio 2020 Jan;10(1):135-146
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
Wu J, Lu K, Zhu M, Xie X, Ding Y, Shao X, Chen Y, Liu J, Xu M, Xu Y, Zhou J, Shen X, Zhu C
Biochemical and biophysical research communications 2020 Jan 22;521(4):984-990
Biochemical and biophysical research communications 2020 Jan 22;521(4):984-990
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
Liao X, Song G, Xu Z, Bu Y, Chang F, Jia F, Xiao X, Ren X, Zhang M, Jia Q
BMC cancer 2020 Jan 13;20(1):31
BMC cancer 2020 Jan 13;20(1):31
TOB1 suppresses proliferation in K-Ras wild-type pancreatic cancer.
Bai Y, Qiao L, Xie N, Li Y, Nie Y, Pan Y, Shi Y, Wang J, Liu N
Cancer medicine 2020 Feb;9(4):1503-1514
Cancer medicine 2020 Feb;9(4):1503-1514
Acetyl-11-keto-β-boswellic acid triggers premature senescence via induction of DNA damage accompanied by impairment of DNA repair genes in hepatocellular carcinoma cells in vitro and in vivo.
Wang S, Wang H, Sun B, Li D, Wu J, Li J, Tian X, Qin C, Chang H, Liu Y
Fundamental & clinical pharmacology 2020 Feb;34(1):65-76
Fundamental & clinical pharmacology 2020 Feb;34(1):65-76
Pizotifen inhibits the proliferation and invasion of gastric cancer cells.
Jiang Y, Wang W, Wu X, Shi J
Experimental and therapeutic medicine 2020 Feb;19(2):817-824
Experimental and therapeutic medicine 2020 Feb;19(2):817-824
Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.
Liu Y, Zhang M, He T, Yang W, Wang L, Zhang L, Guo M
Clinical epigenetics 2020 Feb 10;12(1):22
Clinical epigenetics 2020 Feb 10;12(1):22
Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress.
Gou W, Luo N, Wei H, Wu H, Yu X, Duan Y, Bi C, Ning H, Hou W, Li Y
Pharmaceutical biology 2020 Dec;58(1):707-715
Pharmaceutical biology 2020 Dec;58(1):707-715
Heat-Shock protein A12A is a novel PCNA-binding protein and promotes hepatocellular carcinoma growth.
Cheng H, Cao X, Min X, Zhang X, Kong Q, Mao Q, Li R, Xue B, Fang L, Liu L, Ding Z
The FEBS journal 2020 Dec;287(24):5464-5477
The FEBS journal 2020 Dec;287(24):5464-5477
Sirtuin 5 regulates the proliferation, invasion and migration of prostate cancer cells through acetyl-CoA acetyltransferase 1.
Guan J, Jiang X, Gai J, Sun X, Zhao J, Li J, Li Y, Cheng M, Du T, Fu L, Li Q
Journal of cellular and molecular medicine 2020 Dec;24(23):14039-14049
Journal of cellular and molecular medicine 2020 Dec;24(23):14039-14049
Notch3 is involved in the proliferation of renal cancer cells via regulation of cell cycle progression and HIF-2α.
Han Q, Han F, Fan Y, Lian B, Xiao J, Sun W, Han D, Kou H, Li C, Wu B
Oncology letters 2020 Dec;20(6):379
Oncology letters 2020 Dec;20(6):379
MicroRNA-1236-3p inhibits human osteosarcoma growth.
Li J, Chen J, Hu Z, Xu W
Oncology letters 2020 Dec;20(6):367
Oncology letters 2020 Dec;20(6):367
GEF-independent Ran activation shifts a fraction of the protein to the cytoplasm and promotes cell proliferation.
Zhou J, Tan Y, Zhang Y, Tong A, Shen X, Sun X, Jia D, Sun Q
Molecular biomedicine 2020 Dec 30;1(1):18
Molecular biomedicine 2020 Dec 30;1(1):18
S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression.
He W, Zhang J, Liu B, Liu X, Liu G, Xie L, He J, Wei M, Li K, Ma J, Dong R, Ma D, Dong K, Ye M
Molecular therapy oncolytics 2020 Dec 16;19:149-162
Molecular therapy oncolytics 2020 Dec 16;19:149-162
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Liu D, Zhang H, Cui M, Chen C, Feng Y
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
TMEM16A-inhibitor loaded pH-responsive nanoparticles: A novel dual-targeting antitumor therapy for lung adenocarcinoma.
Guo S, Qiu L, Chen Y, Wang X, Ma B, Qu C, Cui J, Zhang H, Xing C, Zhan Y, An H
Biochemical pharmacology 2020 Aug;178:114062
Biochemical pharmacology 2020 Aug;178:114062
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.
Deng X, Zhao J, Qu L, Duan Z, Fu R, Zhu C, Fan D
Biochemical pharmacology 2020 Aug;178:114038
Biochemical pharmacology 2020 Aug;178:114038
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Liu YC, Tsai JJ, Weng YS, Hsu FT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Long Non-coding RNA PEBP1P2 Suppresses Proliferative VSMCs Phenotypic Switching and Proliferation in Atherosclerosis.
He X, Lian Z, Yang Y, Wang Z, Fu X, Liu Y, Li M, Tian J, Yu T, Xin H
Molecular therapy. Nucleic acids 2020 Aug 19;22:84-98
Molecular therapy. Nucleic acids 2020 Aug 19;22:84-98
Prazosin inhibits the proliferation and survival of acute myeloid leukaemia cells through down-regulating TNS1.
Sun X, Yang S, Song W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109731
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Apr;124:109731
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Chen Z, Yuan SJ, Li K, Zhang Q, Li TF, An HC, Xu HZ, Yue Y, Han M, Xu YH, Komatsu N, Zhao L, Chen X
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
Li X, Zhang Y, Chai X, Zhou S, Zhang H, He J, Zhou R, Cai L, Chen L, Tao G
American journal of cancer research 2019;9(5):887-905
American journal of cancer research 2019;9(5):887-905
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473
Theranostics 2019;9(5):1453-1473
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L
Theranostics 2019;9(17):5065-5084
Theranostics 2019;9(17):5065-5084
Celastrol attenuates ox-LDL-induced mesangial cell proliferation via suppressing NLRP3 inflammasome activation.
Sun Z, Li Y, Qian Y, Wu M, Huang S, Zhang A, Zhang Y, Jia Z
Cell death discovery 2019;5:114
Cell death discovery 2019;5:114
GRP78 regulates milk biosynthesis and the proliferation of bovinemammaryepithelial cells through the mTOR signaling pathway.
Liu Y, Wang X, Zhen Z, Yu Y, Qiu Y, Xiang W
Cellular & molecular biology letters 2019;24:57
Cellular & molecular biology letters 2019;24:57
Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.
Li W, Cao J, Liu J, Chu W, Zhang C, Chen S, Kang Z
Cellular & molecular biology letters 2019;24:19
Cellular & molecular biology letters 2019;24:19
LncRNA FEZF1-AS1 Promotes TGF-β2-Mediated Proliferation and Migration in Human Lens Epithelial Cells SRA01/04.
Wang Y, Chen L, Gu Y, Wang Y, Yuan Y, Zhu Q, Bi M, Gu S
Journal of ophthalmology 2019;2019:4736203
Journal of ophthalmology 2019;2019:4736203
Strand-specific miR-28-3p and miR-28-5p have differential effects on nasopharyngeal cancer cells proliferation, apoptosis, migration and invasion.
Lv Y, Yang H, Ma X, Wu G
Cancer cell international 2019;19:187
Cancer cell international 2019;19:187
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, Hu X, Liang H, Wen N, Zhang S, Guo B, Zhang L
International journal of medical sciences 2019;16(12):1573-1582
International journal of medical sciences 2019;16(12):1573-1582
Adiponectin Suppresses Human Pancreatic Cancer Growth through Attenuating the β-Catenin Signaling Pathway.
Jiang J, Fan Y, Zhang W, Shen Y, Liu T, Yao M, Gu J, Tu H, Gan Y
International journal of biological sciences 2019;15(2):253-264
International journal of biological sciences 2019;15(2):253-264
Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
Zhao Y, Zhang Y, Vazirinejad Mehdiabad M, Zhou K, Chen Y, Li L, Guo J, Xu C
PloS one 2019;14(10):e0223232
PloS one 2019;14(10):e0223232
Hypermethylation Of ADHFE1 Promotes The Proliferation Of Colorectal Cancer Cell Via Modulating Cell Cycle Progression.
Hu YH, Ma S, Zhang XN, Zhang ZY, Zhu HF, Ji YH, Li J, Qian XL, Wang YX
OncoTargets and therapy 2019;12:8105-8115
OncoTargets and therapy 2019;12:8105-8115
The effect of MTHFD2 on the proliferation and migration of colorectal cancer cell lines.
Wei Y, Liu P, Li Q, Du J, Chen Y, Wang Y, Shi H, Wang Y, Zhang H, Xue W, Gao Y, Li D, Feng Y, Yan J, Han J, Zhang J
OncoTargets and therapy 2019;12:6361-6370
OncoTargets and therapy 2019;12:6361-6370
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism.
Chen Z, Lin J, Feng S, Chen X, Huang H, Wang C, Yu Y, He Y, Han S, Zheng L, Huang G
OncoTargets and therapy 2019;12:2397-2408
OncoTargets and therapy 2019;12:2397-2408
Dimethyl fumarate suppresses hepatocellular carcinoma progression via activating SOCS3/JAK1/STAT3 signaling pathway.
Liu H, Feng XD, Yang B, Tong RL, Lu YJ, Chen DY, Zhou L, Xie HY, Zheng SS, Wu J
American journal of translational research 2019;11(8):4713-4725
American journal of translational research 2019;11(8):4713-4725
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
Ma Y, Guan L, Han Y, Zhou Y, Li X, Liu Y, Zhang X, Zhang W, Li X, Wang S, Lu W
Cancer management and research 2019;11:5799-5811
Cancer management and research 2019;11:5799-5811
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Zhang Q, Meng X, Qin G, Xue X, Dang N
Journal of Cancer 2019;10(5):1197-1208
Journal of Cancer 2019;10(5):1197-1208
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
Li X, Fu Y, Xia X, Zhang X, Xiao K, Zhuang X, Zhang Y
Cancer medicine 2019 Sep;8(12):5750-5759
Cancer medicine 2019 Sep;8(12):5750-5759
Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle.
Han Y, Liu C, Zhang D, Men H, Huo L, Geng Q, Wang S, Gao Y, Zhang W, Zhang Y, Jia Z
International journal of oncology 2019 Sep;55(3):629-644
International journal of oncology 2019 Sep;55(3):629-644
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Tian F, Yu C, Wu M, Wu X, Wan L, Zhu X
Cell proliferation 2019 Sep;52(5):e12635
Cell proliferation 2019 Sep;52(5):e12635
Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension.
Wang D, Xu H, Wu B, Jiang S, Pan H, Wang R, Chen J
International journal of molecular medicine 2019 Sep;44(3):871-884
International journal of molecular medicine 2019 Sep;44(3):871-884
NUCKS1 is a novel regulator of milk synthesis in and proliferation of mammary epithelial cells via the mTOR signaling pathway.
Yuan X, Zhang M, Ao J, Zhen Z, Gao X, Li M
Journal of cellular physiology 2019 Sep;234(9):15825-15835
Journal of cellular physiology 2019 Sep;234(9):15825-15835
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, Zhong C
Oncology letters 2019 Sep;18(3):3081-3091
Oncology letters 2019 Sep;18(3):3081-3091
CircNR3C1 inhibits proliferation of bladder cancer cells by sponging miR-27a-3p and downregulating cyclin D1 expression.
Zheng F, Wang M, Li Y, Huang C, Tao D, Xie F, Zhang H, Sun J, Zhang C, Gu C, Wang Z, Jiang G
Cancer letters 2019 Sep 28;460:139-151
Cancer letters 2019 Sep 28;460:139-151
miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells.
Xu X, Chen X, Xu M, Liu X, Pan B, Qin J, Xu T, Zeng K, Pan Y, He B, Sun H, Sun L, Wang S
Aging 2019 Sep 22;11(18):7357-7385
Aging 2019 Sep 22;11(18):7357-7385
Regulation of circadian rhythms by NEAT1 mediated TMAO-induced endothelial proliferation: A protective role of asparagus extract.
Wu X, Chen L, Zeb F, Huang Y, An J, Ren J, Yang F, Feng Q
Experimental cell research 2019 Sep 1;382(1):111451
Experimental cell research 2019 Sep 1;382(1):111451
HMQ‑T‑F2 suppresses migration of the human cervical cancer HeLa cells by reversing EMT via the PI3K/Akt signaling pathway.
Dai B, Yu R, Fan M, Yang T, Wang B, Zhang Y
Oncology reports 2019 Oct;42(4):1451-1458
Oncology reports 2019 Oct;42(4):1451-1458
Resveratrol inhibits the proliferation of estrogen receptor-positive breast cancer cells by suppressing EZH2 through the modulation of ERK1/2 signaling.
Hu C, Liu Y, Teng M, Jiao K, Zhen J, Wu M, Li Z
Cell biology and toxicology 2019 Oct;35(5):445-456
Cell biology and toxicology 2019 Oct;35(5):445-456
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Luo XF, Wu XJ, Wei X, Wang AG, Wang SH, Wang JL
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis.
Gao X, Zhang Y, Zhang R, Zhao Z, Zhang H, Wu J, Shen W, Zhong M
Experimental and therapeutic medicine 2019 Oct;18(4):3062-3070
Experimental and therapeutic medicine 2019 Oct;18(4):3062-3070
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
Li F, Wu JT, Wang PF, Qu LZ
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
Yang J, Zeng Z, Qiao L, Jiang X, Ma J, Wang J, Ye S, Ma Q, Wei J, Wu M, Huang X, Ma D, Gao Q
Molecular cancer research : MCR 2019 Oct;17(10):2015-2028
Molecular cancer research : MCR 2019 Oct;17(10):2015-2028
LXRα-mediated downregulation of EGFR suppress colorectal cancer cell proliferation.
Liang X, Cao Y, Xiang S, Xiang Z
Journal of cellular biochemistry 2019 Oct;120(10):17391-17404
Journal of cellular biochemistry 2019 Oct;120(10):17391-17404
RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
Liu X, Yang Y, Xu C, Yang H, Chen S, Chen H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109377
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109377
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.
Shi Y, Fan S, Wu M, Zuo Z, Li X, Jiang L, Shen Q, Xu P, Zeng L, Zhou Y, Huang Y, Yang Z, Zhou J, Gao J, Zhou H, Xu S, Ji H, Shi P, Wu DD, Yang C, Chen Y
Nature communications 2019 Oct 25;10(1):4892
Nature communications 2019 Oct 25;10(1):4892
O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion.
Han X, Li X, Liu H, Zhang H, Li A, Dong M, Xu Y, Yan B, Sui L, Kong Y
Oncology reports 2019 Nov;42(5):2065-2074
Oncology reports 2019 Nov;42(5):2065-2074
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells.
Wang Z, Zhang M, Shan R, Wang YJ, Chen J, Huang J, Sun LQ, Zhou WB
Oncology reports 2019 Nov;42(5):1915-1923
Oncology reports 2019 Nov;42(5):1915-1923
Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM.
Cheng X, Tan S, Duan F, Yuan Q, Li Q, Deng G
Breast cancer (Tokyo, Japan) 2019 Nov;26(6):766-775
Breast cancer (Tokyo, Japan) 2019 Nov;26(6):766-775
Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway.
Yue G, Chen C, Bai L, Wang G, Huang Y, Wang Y, Cui H, Xiao Y
Molecular medicine reports 2019 Nov;20(5):4551-4557
Molecular medicine reports 2019 Nov;20(5):4551-4557
Agmatinase promotes the lung adenocarcinoma tumorigenesis by activating the NO-MAPKs-PI3K/Akt pathway.
Zhu HE, Yin JY, Chen DX, He S, Chen H
Cell death & disease 2019 Nov 7;10(11):854
Cell death & disease 2019 Nov 7;10(11):854
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
Wang Q, Lv Q, Bian H, Yang L, Guo KL, Ye SS, Dong XF, Tao LL
Cancer medicine 2019 May;8(5):2360-2371
Cancer medicine 2019 May;8(5):2360-2371
piRNA-DQ722010 contributes to prostate hyperplasia of the male offspring mice after the maternal exposed to microcystin-leucine arginine.
Han R, Zhang L, Gan W, Fu K, Jiang K, Ding J, Wu J, Han X, Li D
The Prostate 2019 May;79(7):798-812
The Prostate 2019 May;79(7):798-812
Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia.
Peng W, Tong C, Li L, Huang C, Ran Y, Chen X, Bai Y, Liu Y, Zhao J, Tan B, Luo X, Wang H, Wen L, Zhang C, Zhang H, Ding Y, Qi H, Baker PN
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6327-6338
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6327-6338
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Wu W, He K, Guo Q, Chen J, Zhang M, Huang K, Yang D, Wu L, Deng Y, Luo X, Yu H, Ding Q, Xiang G
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
miR-340-FHL2 axis inhibits cell growth and metastasis in ovarian cancer.
Huang Z, Li Q, Luo K, Zhang Q, Geng J, Zhou X, Xu Y, Qian M, Zhang JA, Ji L, Wu J
Cell death & disease 2019 May 8;10(5):372
Cell death & disease 2019 May 8;10(5):372
MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/β-catenin pathway in acute myeloid leukemia.
Liu B, Ma H, Liu Q, Xiao Y, Pan S, Zhou H, Jia L
Journal of experimental & clinical cancer research : CR 2019 May 16;38(1):200
Journal of experimental & clinical cancer research : CR 2019 May 16;38(1):200
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Yanchun M, Yi W, Lu W, Yu Q, Jian Y, Pengzhou K, Ting Y, Hongyi L, Fang W, Xiaolong C, Yongping C
European journal of pharmacology 2019 May 15;851:43-51
European journal of pharmacology 2019 May 15;851:43-51
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, Zhang B, Sun C, Ning J, Feng L, Zhang H, Ma X
Toxicology and applied pharmacology 2019 May 15;371:63-73
Toxicology and applied pharmacology 2019 May 15;371:63-73
Downregulation of EIF5A2 by miR-221-3p inhibits cell proliferation, promotes cell cycle arrest and apoptosis in medulloblastoma cells.
Yang Y, Cui H, Wang X
Bioscience, biotechnology, and biochemistry 2019 Mar;83(3):400-408
Bioscience, biotechnology, and biochemistry 2019 Mar;83(3):400-408
Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression.
Zhang X, Yang X, Zhu S, Li Q, Zou N
Oncology reports 2019 Mar;41(3):1960-1970
Oncology reports 2019 Mar;41(3):1960-1970
UNBS5162 inhibits SKOV3 ovarian cancer cell proliferation by regulating the PI3K/AKT signalling pathway.
Wang Q, Shi W
Oncology letters 2019 Mar;17(3):2976-2982
Oncology letters 2019 Mar;17(3):2976-2982
A Molecular Targeted Immunotherapeutic Strategy for Ulcerative Colitis via Dual-targeting Nanoparticles Delivering miR-146b to Intestinal Macrophages.
Deng F, He S, Cui S, Shi Y, Tan Y, Li Z, Huang C, Liu D, Zhi F, Peng L
Journal of Crohn's & colitis 2019 Mar 30;13(4):482-494
Journal of Crohn's & colitis 2019 Mar 30;13(4):482-494
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability.
Shen Z, Liao X, Shao Z, Feng M, Yuan J, Wang S, Gan S, Ha Y, He Z, Jie W
BMC cancer 2019 Mar 22;19(1):262
BMC cancer 2019 Mar 22;19(1):262
CORO1C expression is associated with poor survival rates in gastric cancer and promotes metastasis in vitro.
Cheng X, Wang X, Wu Z, Tan S, Zhu T, Ding K
FEBS open bio 2019 Jun;9(6):1097-1108
FEBS open bio 2019 Jun;9(6):1097-1108
A miR-567-PIK3AP1-PI3K/AKT-c-Myc feedback loop regulates tumour growth and chemoresistance in gastric cancer.
Zhang F, Li K, Yao X, Wang H, Li W, Wu J, Li M, Zhou R, Xu L, Zhao L
EBioMedicine 2019 Jun;44:311-321
EBioMedicine 2019 Jun;44:311-321
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
Dong S, Ji J, Hu L, Wang H
Life sciences 2019 Jun 15;227:20-29
Life sciences 2019 Jun 15;227:20-29
Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
Lu GQ, Li XY, Mohamed O K, Wang D, Meng FH
European journal of medicinal chemistry 2019 Jun 1;171:282-296
European journal of medicinal chemistry 2019 Jun 1;171:282-296
IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation.
Zhang W, Lu Y, Li X, Zhang J, Lin W, Zhang W, Zheng L, Li X
Journal of experimental & clinical cancer research : CR 2019 Jul 9;38(1):296
Journal of experimental & clinical cancer research : CR 2019 Jul 9;38(1):296
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
Deng L, Sun J, Chen X, Liu L, Wu D
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
miR-629-5p promotes growth and metastasis of hepatocellular carcinoma by activating β-catenin.
Tao X, Yang X, Wu K, Yang L, Huang Y, Jin Q, Chen S
Experimental cell research 2019 Jul 15;380(2):124-130
Experimental cell research 2019 Jul 15;380(2):124-130
Thyroid hormone (T(3)) is involved in inhibiting the proliferation of newborn calf Sertoli cells via the PI3K/Akt signaling pathway in vitro.
Wang C, Zheng P, Adeniran SO, Ma M, Huang F, Adegoke EO, Zhang G
Theriogenology 2019 Jul 15;133:1-9
Theriogenology 2019 Jul 15;133:1-9
SND1 promotes the proliferation of osteosarcoma cells by upregulating COX‑2/PGE2 expression via activation of NF‑κB.
Zhou M, Wang A, Yin B, Wu D, Han S, Zhang W, Liu J, Sun K
Oncology reports 2019 Jan;41(1):579-589
Oncology reports 2019 Jan;41(1):579-589
Nuclear factor I/B promotes colorectal cancer cell proliferation, epithelial-mesenchymal transition and 5-fluorouracil resistance.
Liu Z, Chen J, Yuan W, Ruan H, Shu Y, Ji J, Wu L, Tang Q, Zhou Z, Zhang X, Cheng Y, He S, Shu X
Cancer science 2019 Jan;110(1):86-98
Cancer science 2019 Jan;110(1):86-98
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Zhang X, Liu J, Gu Y, Sun C, Qu F
Cell biology international 2019 Feb;43(2):158-166
Cell biology international 2019 Feb;43(2):158-166
Regulation of Cell Cycle Regulatory Proteins by MicroRNAs in Uterine Leiomyoma.
Chuang TD, Khorram O
Reproductive sciences (Thousand Oaks, Calif.) 2019 Feb;26(2):250-258
Reproductive sciences (Thousand Oaks, Calif.) 2019 Feb;26(2):250-258
Down-regulation of miR-1181 indicates a dismal prognosis for nasopharyngeal carcinoma and promoted cell proliferation and metastasis by modulating Wnt/β-catenin signaling.
Hua X, Fan KC
European review for medical and pharmacological sciences 2019 Feb;23(3):1077-1086
European review for medical and pharmacological sciences 2019 Feb;23(3):1077-1086
Overexpression of SIRT4 inhibits the proliferation of gastric cancer cells through cell cycle arrest.
Hu Y, Lin J, Lin Y, Chen X, Zhu G, Huang G
Oncology letters 2019 Feb;17(2):2171-2176
Oncology letters 2019 Feb;17(2):2171-2176
JTC-801 inhibits the proliferation and metastasis of the Hep G2 hepatoblastoma cell line by regulating the phosphatidylinositol 3-kinase/protein kinase B signalling pathway.
Zhao B, Hu T
Oncology letters 2019 Feb;17(2):1939-1945
Oncology letters 2019 Feb;17(2):1939-1945
Retracted: Inhibition of microRNA-940 suppresses the migration and invasion of human osteosarcoma cells through the secreted frizzled-related protein 1-mediated Wnt/β-catenin signaling pathway.
Lin ZW, Zhang W, Jiang SD, Wei WB, Li XF
Journal of cellular biochemistry 2019 Feb;120(2):2657-2670
Journal of cellular biochemistry 2019 Feb;120(2):2657-2670
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Zhang Y, Li Q, Yu S, Zhu C, Zhang Z, Cao H, Xu J
Biochemical and biophysical research communications 2019 Feb 12;509(3):753-762
Biochemical and biophysical research communications 2019 Feb 12;509(3):753-762
Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway.
Li T, Xiong Y, Wang Q, Chen F, Zeng Y, Yu X, Wang Y, Zhou F, Zhou Y
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):4001-4011
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):4001-4011
CircCDYL inhibits the expression of C-MYC to suppress cell growth and migration in bladder cancer.
Sun J, Zhang H, Tao D, Xie F, Liu F, Gu C, Wang M, Wang L, Jiang G, Wang Z, Xiao X
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):1349-1356
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):1349-1356
Histone deacetylases inhibitor MS-275 suppresses human esophageal squamous cell carcinoma cell growth and progression via the PI3K/Akt/mTOR pathway.
Ma S, Liu T, Xu L, Wang Y, Zhou J, Huang T, Li P, Liu H, Zhang Y, Zhou X, Cui Y, Zang X, Wang Y, Guan F
Journal of cellular physiology 2019 Dec;234(12):22400-22410
Journal of cellular physiology 2019 Dec;234(12):22400-22410
HOXC13-AS promotes breast cancer cell growth through regulating miR-497-5p/PTEN axis.
Li X, Wang Q, Rui Y, Zhang C, Wang W, Gu J, Tang J, Ding Y
Journal of cellular physiology 2019 Dec;234(12):22343-22351
Journal of cellular physiology 2019 Dec;234(12):22343-22351
MiR-6838-5p suppresses cell metastasis and the EMT process in triple-negative breast cancer by targeting WNT3A to inhibit the Wnt pathway.
Liu G, Wang P, Zhang H
The journal of gene medicine 2019 Dec;21(12):e3129
The journal of gene medicine 2019 Dec;21(12):e3129
MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.
Guan F, Zhou X, Li P, Wang Y, Liu M, Li F, Cui Y, Huang T, Yao M, Zhang Y, Ma J, Ma S
Progress in neuro-psychopharmacology & biological psychiatry 2019 Dec 20;95:109684
Progress in neuro-psychopharmacology & biological psychiatry 2019 Dec 20;95:109684
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
Liu JZ, Hu YL, Feng Y, Guo YB, Liu YF, Yang JL, Mao QS, Xue WJ
Experimental cell research 2019 Dec 15;385(2):111691
Experimental cell research 2019 Dec 15;385(2):111691
LncRNA AC007271.3 promotes cell proliferation, invasion, migration and inhibits cell apoptosis of OSCC via the Wnt/β-catenin signaling pathway.
Shao TR, Zheng ZN, Chen YC, Wu QQ, Huang GZ, Li F, Zeng WS, Lv XZ
Life sciences 2019 Dec 15;239:117087
Life sciences 2019 Dec 15;239:117087
Paper/polymer composited microfluidic platform for screening cell viability and protein expression under a chemical gradient environment.
Lei KF, Goh A, Huang CH
Talanta 2019 Dec 1;205:120124
Talanta 2019 Dec 1;205:120124
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment.
Assani G, Segbo J, Yu X, Yessoufou A, Xiong Y, Zhou F, Zhou Y
Asian Pacific journal of cancer prevention : APJCP 2019 Dec 1;20(12):3679-3687
Asian Pacific journal of cancer prevention : APJCP 2019 Dec 1;20(12):3679-3687
Angiotensin blockade attenuates diabetic nephropathy in hypogonadal adult male rats.
Makary S, Abdo M, Hassan WA, Tawfik MK
Canadian journal of physiology and pharmacology 2019 Aug;97(8):708-720
Canadian journal of physiology and pharmacology 2019 Aug;97(8):708-720
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
(-)-Epicatechin mitigates radiation-induced intestinal injury and promotes intestinal regeneration via suppressing oxidative stress.
Li Y, Ma S, Zhang Y, Yao M, Zhu X, Guan F
Free radical research 2019 Aug;53(8):851-864
Free radical research 2019 Aug;53(8):851-864
RING finger protein 10 is a potential drug target for diabetic vascular complications.
Li S, Yu G, Huang W, Wang R, Pu P, Chen M
Molecular medicine reports 2019 Aug;20(2):931-938
Molecular medicine reports 2019 Aug;20(2):931-938
Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway.
Zheng M, Tian C, Fan T, Xu B
Experimental eye research 2019 Aug;185:107681
Experimental eye research 2019 Aug;185:107681
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Song T, Ma K, Zhao C, Yang J, Liu J
Oncology letters 2019 Aug;18(2):2043-2049
Oncology letters 2019 Aug;18(2):2043-2049
Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer.
Pan JH, Zhou H, Zhu SB, Huang JL, Zhao XX, Ding H, Qin L, Pan YL
Journal of cellular physiology 2019 Apr;234(4):4385-4395
Journal of cellular physiology 2019 Apr;234(4):4385-4395
Enhanced expression of circular RNA hsa_circ_000984 promotes cells proliferation and metastasis in non-small cell lung cancer by modulating Wnt/β-catenin pathway.
Li XY, Liu YR, Zhou JH, Li W, Guo HH, Ma HP
European review for medical and pharmacological sciences 2019 Apr;23(8):3366-3374
European review for medical and pharmacological sciences 2019 Apr;23(8):3366-3374
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, Peng W, Han D, Zhou X, Wu J, He H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo.
Xiong Y, Li T, Assani G, Ling H, Zhou Q, Zeng Y, Zhou F, Zhou Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108602
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108602
Poly(ADP-ribose) Polymerase-1 is required for hepatocyte proliferation and liver regeneration in mice.
Ju C, Liu C, Yan S, Wang Y, Mao X, Liang M, Huang K
Biochemical and biophysical research communications 2019 Apr 9;511(3):531-535
Biochemical and biophysical research communications 2019 Apr 9;511(3):531-535
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
Lin F, Xie YJ, Zhang XK, Huang TJ, Xu HF, Mei Y, Liang H, Hu H, Lin ST, Luo FF, Lang YH, Peng LX, Qian CN, Huang BJ
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
Exogenous biological renal support ameliorates renal pathology after ischemia reperfusion injury in elderly mice.
Liu D, Yin Z, Huang Q, Ren Y, Li D, Wang L, Cui S, Zhang Y, Ning Y, Lun L, Cai G, Bai X, Sun X, Chen X
Aging 2019 Apr 12;11(7):2031-2044
Aging 2019 Apr 12;11(7):2031-2044
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
Li K, Xu X, He Y, Tian Y, Pan W, Xu L, Ma Y, Gao Y, Gao J, Qi Y, Wei L, Zhang J
Journal of Cancer 2018;9(10):1821-1835
Journal of Cancer 2018;9(10):1821-1835
The Long Noncoding RNA 150Rik Promotes Mesangial Cell Proliferation via miR-451/IGF1R/p38 MAPK Signaling in Diabetic Nephropathy.
Zhang Y, Sun Y, Peng R, Liu H, He W, Zhang L, Peng H, Zhang Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(3):1410-1428
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(3):1410-1428
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Wang Y, Tang H, He G, Shi Y, Kang X, Lyu J, Zhou M, Zhu M, Zhang J, Tang K
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
CircRNA8924 Promotes Cervical Cancer Cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8.
Liu J, Wang D, Long Z, Liu J, Li W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(1):173-184
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(1):173-184
Bushenshugan Formula Attenuates the Development of Lung Cancer by Inhibiting Epithelial-Mesenchymal Transition.
Fan Z, Xue W, Dou M, Li L, Lu J, Ma B, Deng X, Zhang M, Zhai Y, Wang S, Zhao J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):1977-1988
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(5):1977-1988
Down-regulation of long non-coding RNA ITGB2-AS1 inhibits osteosarcoma proliferation and metastasis by repressing Wnt/β-catenin signalling and predicts favourable prognosis.
Dai J, Xu LJ, Han GD, Jiang HT, Sun HL, Zhu GT, Tang XM
Artificial cells, nanomedicine, and biotechnology 2018;46(sup3):S783-S790
Artificial cells, nanomedicine, and biotechnology 2018;46(sup3):S783-S790
Overexpression of Annexin A2 Receptor Inhibits Neovascularization via the Promotion of Krüppel-Like Transcription Factor 2.
Guo T, Song H, Zhao Z, Qi Z, Zhao S
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(4):1617-1627
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(4):1617-1627
SKA3 promotes cell proliferation and migration in cervical cancer by activating the PI3K/Akt signaling pathway.
Hu R, Wang MQ, Niu WB, Wang YJ, Liu YY, Liu LY, Wang M, Zhong J, You HY, Wu XH, Deng N, Lu L, Wei LB
Cancer cell international 2018;18:183
Cancer cell international 2018;18:183
VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2.
Zhao L, Zhu Z, Yao C, Huang Y, Zhi E, Chen H, Tian R, Li P, Yuan Q, Xue Y, Wan Z, Yang C, Gong Y, He Z, Li Z
Cell cycle (Georgetown, Tex.) 2018;17(2):225-239
Cell cycle (Georgetown, Tex.) 2018;17(2):225-239
The protective role of human ghrelin in sepsis: Restoration of CD4 T cell proliferation.
Zhou M, Aziz M, Ochani M, Yang WL, Sharma A, Wang P
PloS one 2018;13(7):e0201139
PloS one 2018;13(7):e0201139
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, Zhang C, Bi Y, Zhang C, Bian H
Chinese medicine 2018;13:17
Chinese medicine 2018;13:17
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Cao S, Chen G, Yan L, Li L, Huang X
OncoTargets and therapy 2018;11:7385-7394
OncoTargets and therapy 2018;11:7385-7394
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Song H, Guo T, Zhao Z, Wei Y, Luo H, Weng W, Zhang R, Zhong M, Chen C, Su J, Shen W
Biomaterials 2018 Sep;178:23-35
Biomaterials 2018 Sep;178:23-35
POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling.
Du Y, Li D, Li N, Su C, Yang C, Lin C, Chen M, Wu R, Li X, Hu G
Cell death & disease 2018 Sep 24;9(10):995
Cell death & disease 2018 Sep 24;9(10):995
LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
Zeng K, Chen X, Hu X, Liu X, Xu T, Sun H, Pan Y, He B, Wang S
Oncogene 2018 Oct;37(41):5534-5551
Oncogene 2018 Oct;37(41):5534-5551
miR-25 Promotes Melanoma Progression by regulating RNA binding motif protein 47.
Jiang QQ, Liu WB
Medecine sciences : M/S 2018 Oct;34 Focus issue F1:59-65
Medecine sciences : M/S 2018 Oct;34 Focus issue F1:59-65
Knockdown of Sox2 Inhibits OS Cells Invasion and Migration via Modulating Wnt/β-Catenin Signaling Pathway.
Tang L, Wang D, Gu D
Pathology oncology research : POR 2018 Oct;24(4):907-913
Pathology oncology research : POR 2018 Oct;24(4):907-913
Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis.
Xie F, Li Y, Wang M, Huang C, Tao D, Zheng F, Zhang H, Zeng F, Xiao X, Jiang G
Molecular cancer 2018 Oct 3;17(1):144
Molecular cancer 2018 Oct 3;17(1):144
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
Yu M, Wang H, Liu J, Qin H, Liu S, Yan Q
FEBS letters 2018 Nov;592(22):3696-3707
FEBS letters 2018 Nov;592(22):3696-3707
MiR-1301-3p inhibits human breast cancer cell proliferation by regulating cell cycle progression and apoptosis through directly targeting ICT1.
Peng X, Yan B, Shen Y
Breast cancer (Tokyo, Japan) 2018 Nov;25(6):742-752
Breast cancer (Tokyo, Japan) 2018 Nov;25(6):742-752
Aclidinium inhibits proliferation and metastasis of ovarian cancer SKOV3 cells via downregulating PI3K/AKT/mTOR signaling pathway.
Qiao J, Wang WJ, Zhang Y
Oncology letters 2018 Nov;16(5):6417-6422
Oncology letters 2018 Nov;16(5):6417-6422
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Yin LL, Wen XM, Li M, Xu YM, Zhao XF, Li J, Wang XW
Oncology letters 2018 Nov;16(5):6283-6292
Oncology letters 2018 Nov;16(5):6283-6292
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Tian T, Sun J, Wang J, Liu Y, Liu H
Oncology letters 2018 Nov;16(5):6133-6139
Oncology letters 2018 Nov;16(5):6133-6139
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Chen X, Liu C, Zhao R, Zhao P, Wu J, Zhou N, Ying M
Molecular pharmaceutics 2018 Nov 5;15(11):4974-4984
Molecular pharmaceutics 2018 Nov 5;15(11):4974-4984
Differential anticancer activities of arsenic trioxide on head and neck cancer cells with different human papillomavirus status.
Du S, Liu K, Gao P, Li Z, Zheng J
Life sciences 2018 Nov 1;212:182-193
Life sciences 2018 Nov 1;212:182-193
Mitochondrial ATAD3A regulates milk biosynthesis and proliferation of mammary epithelial cells from dairy cow via the mTOR pathway.
Chen D, Yuan X, Liu L, Zhang M, Qu B, Zhen Z, Gao X
Cell biology international 2018 May;42(5):533-542
Cell biology international 2018 May;42(5):533-542
Inhibitory effects of aesculetin on the proliferation of colon cancer cells by the Wnt/β-catenin signaling pathway.
Li T, Zhang L, Huo X
Oncology letters 2018 May;15(5):7118-7122
Oncology letters 2018 May;15(5):7118-7122
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
Liu YP, Li L, Xu L, Dai EN, Chen WD
Oncology letters 2018 May;15(5):6527-6532
Oncology letters 2018 May;15(5):6527-6532
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, Geng S, Wu J, Zhong C, Li M
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Journal of cellular biochemistry 2018 May;119(5):4134-4141
The NK1 receptor antagonist NKP608 inhibits proliferation of human colorectal cancer cells via Wnt signaling pathway.
Niu XL, Hou JF, Li JX
Biological research 2018 May 30;51(1):14
Biological research 2018 May 30;51(1):14
MicroRNA-1247 inhibits cell proliferation by directly targeting ZNF346 in childhood neuroblastoma.
Wu T, Lin Y, Xie Z
Biological research 2018 May 24;51(1):13
Biological research 2018 May 24;51(1):13
HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer.
Fu F, Wang T, Wu Z, Feng Y, Wang W, Zhou S, Ma X, Wang S
Cell death & disease 2018 May 22;9(6):594
Cell death & disease 2018 May 22;9(6):594
CCN1/Cyr61 enhances the function of hepatic stellate cells in promoting the progression of hepatocellular carcinoma.
Li ZQ, Wu WR, Zhao C, Zhao C, Zhang XL, Yang Z, Pan J, Si WK
International journal of molecular medicine 2018 Mar;41(3):1518-1528
International journal of molecular medicine 2018 Mar;41(3):1518-1528
Actin-capping protein CapG is associated with prognosis, proliferation and metastasis in human glioma.
Yun DP, Wang YQ, Meng DL, Ji YY, Chen JX, Chen HY, Lu DR
Oncology reports 2018 Mar;39(3):1011-1022
Oncology reports 2018 Mar;39(3):1011-1022
Annexin A2 positively regulates milk synthesis and proliferation of bovine mammary epithelial cells through the mTOR signaling pathway.
Zhang M, Chen D, Zhen Z, Ao J, Yuan X, Gao X
Journal of cellular physiology 2018 Mar;233(3):2464-2475
Journal of cellular physiology 2018 Mar;233(3):2464-2475
Incorporation of Cerium Oxide into Hydroxyapatite Coating Protects Bone Marrow Stromal Cells Against H(2)O(2)-Induced Inhibition of Osteogenic Differentiation.
Li K, Shen Q, Xie Y, You M, Huang L, Zheng X
Biological trace element research 2018 Mar;182(1):91-104
Biological trace element research 2018 Mar;182(1):91-104
Cellular response to persistent foot-and-mouth disease virus infection is linked to specific types of alterations in the host cell transcriptome.
Han L, Xin X, Wang H, Li J, Hao Y, Wang M, Zheng C, Shen C
Scientific reports 2018 Mar 22;8(1):5074
Scientific reports 2018 Mar 22;8(1):5074
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
Qian W, Kong X, Zhang T, Wang D, Song J, Li Y, Li X, Geng H, Min J, Kong Q, Liu J, Liu Z, Wang D, Zhang Z, Yu D, Zhong C
Oncogenesis 2018 Mar 13;7(3):24
Oncogenesis 2018 Mar 13;7(3):24
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Zhang Q, Li XT, Chen Y, Chen JQ, Zhu JY, Meng Y, Wang XQ, Li Y, Geng SS, Xie CF, Wu JS, Zhong CY, Han HY
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
Jia W, Jiang X, Liu W, Wang L, Zhu B, Zhu H, Liu X, Zhong M, Xie D, Huang W, Jia W, Li S, Liu X, Zuo X, Cheng D, Dai J, Ren C
International journal of oncology 2018 Jun;52(6):1787-1800
International journal of oncology 2018 Jun;52(6):1787-1800
MicroRNA-384 inhibits the progression of breast cancer by targeting ACVR1.
Wang Y, Zhang Z, Wang J
Oncology reports 2018 Jun;39(6):2563-2574
Oncology reports 2018 Jun;39(6):2563-2574
Curcumin-Loaded Solid Lipid Nanoparticles Enhanced Anticancer Efficiency in Breast Cancer.
Wang W, Chen T, Xu H, Ren B, Cheng X, Qi R, Liu H, Wang Y, Yan L, Chen S, Yang Q, Chen C
Molecules (Basel, Switzerland) 2018 Jun 29;23(7)
Molecules (Basel, Switzerland) 2018 Jun 29;23(7)
NF-κB and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.
Zeng GZ, Wang Z, Zhao LM, Fan JT, Tan NH
Journal of ethnopharmacology 2018 Jun 28;220:220-227
Journal of ethnopharmacology 2018 Jun 28;220:220-227
LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial-mesenchymal transition through the Notch1 signaling pathway.
Liu W, Zhang J, Gan X, Shen F, Yang X, Du N, Xia D, Liu L, Qiao L, Pan J, Sun Y, Xi X
Cancer medicine 2018 Jul;7(7):3132-3142
Cancer medicine 2018 Jul;7(7):3132-3142
DEAD-box helicase 6 (DDX6) is a new negative regulator for milk synthesis and proliferation of bovine mammary epithelial cells.
Zhen Z, Zhang M, Yuan X, Qu B, Yu Y, Gao X, Qiu Y
In vitro cellular & developmental biology. Animal 2018 Jan;54(1):52-60
In vitro cellular & developmental biology. Animal 2018 Jan;54(1):52-60
UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway.
He D, Zhang S
Molecular medicine reports 2018 Jan;17(1):549-555
Molecular medicine reports 2018 Jan;17(1):549-555
High expression of TMEM40 is associated with the malignant behavior and tumorigenesis in bladder cancer.
Zhang ZF, Zhang HR, Zhang QY, Lai SY, Feng YZ, Zhou Y, Zheng SR, Shi R, Zhou JY
Journal of translational medicine 2018 Jan 19;16(1):9
Journal of translational medicine 2018 Jan 19;16(1):9
Involvement of mitochondrial fission in calcium sensing receptor-mediated vascular smooth muscle cells proliferation during hypertension.
Zhang X, Chen W, Li J, Qi S, Hong S, Wang Y, Gao L, Shi Z, Liu Y, Liu W, Chi Y, Liu C, Fu Y, Yin X
Biochemical and biophysical research communications 2018 Jan 1;495(1):454-460
Biochemical and biophysical research communications 2018 Jan 1;495(1):454-460
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Xiao Y, Tian C, Huang T, Han B, Wang M, Ma H, Li Z, Ye X, Li X
Life sciences 2018 Jan 1;192:259-269
Life sciences 2018 Jan 1;192:259-269
Vascular peroxidase 1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation, apoptosis resistance and migration.
You B, Liu Y, Chen J, Huang X, Peng H, Liu Z, Tang Y, Zhang K, Xu Q, Li X, Cheng G, Shi R, Zhang G
Cardiovascular research 2018 Jan 1;114(1):188-199
Cardiovascular research 2018 Jan 1;114(1):188-199
YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury.
Deng F, Peng L, Li Z, Tan G, Liang E, Chen S, Zhao X, Zhi F
Cell death & disease 2018 Feb 2;9(2):153
Cell death & disease 2018 Feb 2;9(2):153
PTBP3 splicing factor promotes hepatocellular carcinoma by destroying the splicing balance of NEAT1 and pre-miR-612.
Yang X, Qu S, Wang L, Zhang H, Yang Z, Wang J, Dai B, Tao K, Shang R, Liu Z, Li X, Zhang Z, Xia C, Ma B, Liu W, Li H, Dou K
Oncogene 2018 Dec;37(50):6399-6413
Oncogene 2018 Dec;37(50):6399-6413
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Chen Y, Li Y, Wang XQ, Meng Y, Zhang Q, Zhu JY, Chen JQ, Cao WS, Wang XQ, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway.
Liu B, Xu L, Dai EN, Tian JX, Li JM
Bioscience reports 2018 Dec 21;38(6)
Bioscience reports 2018 Dec 21;38(6)
Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.
Li K, Ma YB, Zhang Z, Tian YH, Xu XL, He YQ, Xu L, Gao Y, Pan WT, Song WJ, He X, Wei L
Cancer medicine 2018 Aug;7(8):3875-3888
Cancer medicine 2018 Aug;7(8):3875-3888
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
Yu Z, Tian X, Peng Y, Sun Z, Wang C, Tang N, Li B, Jian Y, Wang W, Huo X, Ma X
Journal of pineal research 2018 Aug;65(1):e12478
Journal of pineal research 2018 Aug;65(1):e12478
Resveratrol inhibits the growth of gastric cancer via the Wnt/β-catenin pathway.
Dai H, Deng HB, Wang YH, Guo JJ
Oncology letters 2018 Aug;16(2):1579-1583
Oncology letters 2018 Aug;16(2):1579-1583
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
Meng M, Chen Y, Jia J, Li L, Yang S
Biological research 2018 Aug 10;51(1):24
Biological research 2018 Aug 10;51(1):24
Telmisartan inhibits NSCLC A549 cell proliferation and migration by regulating the PI3K/AKT signaling pathway.
Zhang S, Wang Y
Oncology letters 2018 Apr;15(4):5859-5864
Oncology letters 2018 Apr;15(4):5859-5864
Synergistic effect of receptor-interacting protein 140 and simvastatin on the inhibition of proliferation and survival of hepatocellular carcinoma cells.
Xia K, Zhang P, Hu J, Hou H, Xiong M, Xiong J, Yan N
Oncology letters 2018 Apr;15(4):4344-4350
Oncology letters 2018 Apr;15(4):4344-4350
Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade.
Lu QB, Wan MY, Wang PY, Zhang CX, Xu DY, Liao X, Sun HJ
Redox biology 2018 Apr;14:656-668
Redox biology 2018 Apr;14:656-668
MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation.
Ren T, Wang J, Zhang H, Yuan P, Zhu J, Wu Y, Huang Q, Guo X, Zhang J, Ji L, Li J, Zhang H, Yang H, Xing J
Antioxidants & redox signaling 2018 Apr 20;28(12):1120-1136
Antioxidants & redox signaling 2018 Apr 20;28(12):1120-1136
Androgen Receptor Is Inactivated and Degraded in Bladder Cancer Cells by Phenyl Glucosamine via miR-449a Restoration.
Guo J, Hu J, Cao R, Chen Q, Li K
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 16;24:2294-2301
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 16;24:2294-2301
Anticancer effect of PP31J isolated from Physalis pubescens L. in human cervical carcinoma cells.
Zeng W, Wang Q, Chen L, Huang L, Zhao X
American journal of translational research 2017;9(5):2466-2472
American journal of translational research 2017;9(5):2466-2472
Histone deacetylase inhibitor NaBut suppresses cell proliferation and induces apoptosis by targeting p21 in multiple myeloma.
Yao R, Han D, Sun X, Fu C, Wu Q, Yao Y, Li H, Li Z, Xu K
American journal of translational research 2017;9(11):4994-5002
American journal of translational research 2017;9(11):4994-5002
Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.
Wang Y, He T, Herman JG, Linghu E, Yang Y, Fuks F, Zhou F, Song L, Guo M
Clinical epigenetics 2017;9:115
Clinical epigenetics 2017;9:115
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Yang HF, Yu M, Jin HD, Yao JQ, Lu ZL, Yabasin IB, Yan Q, Wen QP
Frontiers in physiology 2017;8:510
Frontiers in physiology 2017;8:510
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer.
Wei WJ, Sun ZK, Shen CT, Song HJ, Zhang XY, Qiu ZL, Luo QY
Theranostics 2017;7(4):987-1001
Theranostics 2017;7(4):987-1001
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Sun W, Yang J, Zhang Y, Xi Y, Wen X, Yuan D, Wang Y, Wei C, Wang R, Wu L, Li H, Xu C
Cell & bioscience 2017;7:67
Cell & bioscience 2017;7:67
Therapy Effects of Wogonin on Ovarian Cancer Cells.
Ruibin J, Bo J, Danying W, Chihong Z, Jianguo F, Linhui G
BioMed research international 2017;2017:9381513
BioMed research international 2017;2017:9381513
Metabolic reprogramming induced by inhibition of SLC2A1 suppresses tumor progression in lung adenocarcinoma.
Wang Y, Shi S, Ding Y, Wang Z, Liu S, Yang J, Xu T
International journal of clinical and experimental pathology 2017;10(11):10759-10769
International journal of clinical and experimental pathology 2017;10(11):10759-10769
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
Wang B, Shen J, Wang J
OncoTargets and therapy 2017;10:5303-5309
OncoTargets and therapy 2017;10:5303-5309
CDKL1 promotes tumor proliferation and invasion in colorectal cancer.
Qin C, Ren L, Ji M, Lv S, Wei Y, Zhu D, Lin Q, Xu P, Chang W, Xu J
OncoTargets and therapy 2017;10:1613-1624
OncoTargets and therapy 2017;10:1613-1624
Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer.
Zhang B, Liu Y, Liu D, Yang L
Journal of biosciences 2017 Sep;42(3):417-425
Journal of biosciences 2017 Sep;42(3):417-425
Mono-ADP-ribosylation of histone 3 at arginine-117 promotes proliferation through its interaction with P300.
Ling F, Tang Y, Li M, Li QS, Li X, Yang L, Zhao W, Jin CC, Zeng Z, Liu C, Wu CF, Chen WW, Lin X, Wang YL, Threadgill MD
Oncotarget 2017 Sep 22;8(42):72773-72787
Oncotarget 2017 Sep 22;8(42):72773-72787
Salusin-β mediates high glucose-induced endothelial injury via disruption of AMPK signaling pathway.
Zhu X, Zhou Y, Cai W, Sun H, Qiu L
Biochemical and biophysical research communications 2017 Sep 16;491(2):515-521
Biochemical and biophysical research communications 2017 Sep 16;491(2):515-521
Knockdown of tripartite motif-59 inhibits the malignant processes in human colorectal cancer cells.
Wu W, Chen J, Wu J, Lin J, Yang S, Yu H
Oncology reports 2017 Oct;38(4):2480-2488
Oncology reports 2017 Oct;38(4):2480-2488
Knockdown of Immature Colon Carcinoma Transcript 1 Inhibits Proliferation and Promotes Apoptosis of Non-Small Cell Lung Cancer Cells.
Wang Y, He J, Zhang S, Yang Q, Wang B, Liu Z, Wu X
Technology in cancer research & treatment 2017 Oct;16(5):559-569
Technology in cancer research & treatment 2017 Oct;16(5):559-569
EDIL3 knockdown inhibits retinal angiogenesis through the induction of cell cycle arrest in vitro.
Shen W, Zhu S, Qin H, Zhong M, Wu J, Zhang R, Song H
Molecular medicine reports 2017 Oct;16(4):4054-4060
Molecular medicine reports 2017 Oct;16(4):4054-4060
Downregulation of Cohesin Loading Factor Nipped-B-Like Protein (NIPBL) Induces Cell Cycle Arrest, Apoptosis, and Autophagy of Breast Cancer Cell Lines.
Zhou H, Zheng L, Lu K, Gao Y, Guo L, Xu W, Wang X
Medical science monitor : international medical journal of experimental and clinical research 2017 Oct 7;23:4817-4825
Medical science monitor : international medical journal of experimental and clinical research 2017 Oct 7;23:4817-4825
Twinfilin 1 enhances milk bio-synthesis and proliferation of bovine mammary epithelial cells via the mTOR signaling pathway.
Li L, Liu L, Qu B, Li X, Gao X, Zhang M
Biochemical and biophysical research communications 2017 Oct 21;492(3):289-294
Biochemical and biophysical research communications 2017 Oct 21;492(3):289-294
Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma.
Lin B, Zhou X, Lin S, Wang X, Zhang M, Cao B, Dong Y, Yang S, Wang JM, Guo M, Huang J
Journal of molecular medicine (Berlin, Germany) 2017 Nov;95(11):1237-1249
Journal of molecular medicine (Berlin, Germany) 2017 Nov;95(11):1237-1249
DLEU1 contributes to ovarian carcinoma tumourigenesis and development by interacting with miR-490-3p and altering CDK1 expression.
Wang LL, Sun KX, Wu DD, Xiu YL, Chen X, Chen S, Zong ZH, Sang XB, Liu Y, Zhao Y
Journal of cellular and molecular medicine 2017 Nov;21(11):3055-3065
Journal of cellular and molecular medicine 2017 Nov;21(11):3055-3065
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, Yu D, Zhong C
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Fascaplysin inhibit ovarian cancer cell proliferation and metastasis through inhibiting CDK4.
Chen S, Guan X, Wang LL, Li B, Sang XB, Liu Y, Zhao Y
Gene 2017 Nov 30;635:3-8
Gene 2017 Nov 30;635:3-8
MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication.
Zheng C, Zheng Z, Sun J, Zhang Y, Wei C, Ke X, Liu Y, Deng L, Wang H
Scientific reports 2017 Nov 27;7(1):16422
Scientific reports 2017 Nov 27;7(1):16422
(-)-Curine induces cell cycle arrest and cell death in hepatocellular carcinoma cells in a p53-independent way.
Gong S, Xu D, Zou F, Peng R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:894-901
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:894-901
The transcription factor FOXA1 induces epithelial ovarian cancer tumorigenesis and progression.
Wang LL, Xiu YL, Chen X, Sun KX, Chen S, Wu DD, Liu BL, Zhao Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317706210
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317706210
The soy-derived peptide Vglycin inhibits the growth of colon cancer cells in vitro and in vivo.
Gao C, Sun R, Xie YR, Jiang AL, Lin M, Li M, Chen ZW, Zhang P, Jin H, Feng JP
Experimental biology and medicine (Maywood, N.J.) 2017 May;242(10):1034-1043
Experimental biology and medicine (Maywood, N.J.) 2017 May;242(10):1034-1043
High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling.
He S, Zhong W, Yin L, Wang Y, Qiu Z, Song G
Molecular medicine reports 2017 May;15(5):2567-2573
Molecular medicine reports 2017 May;15(5):2567-2573
Involvement of the activation of Nrf2/HO-1, p38 MAPK signaling pathways and endoplasmic reticulum stress in furazolidone induced cytotoxicity and S phase arrest in human hepatocyte L02 cells: modulation of curcumin.
Dai C, Lei L, Li B, Lin Y, Xiao X, Tang S
Toxicology mechanisms and methods 2017 Mar;27(3):165-172
Toxicology mechanisms and methods 2017 Mar;27(3):165-172
miR-491-5p, mediated by Foxi1, functions as a tumor suppressor by targeting Wnt3a/β-catenin signaling in the development of gastric cancer.
Sun R, Liu Z, Tong D, Yang Y, Guo B, Wang X, Zhao L, Huang C
Cell death & disease 2017 Mar 30;8(3):e2714
Cell death & disease 2017 Mar 30;8(3):e2714
Correlations between TBL1XR1 and recurrence of colorectal cancer.
Liu H, Xu Y, Zhang Q, Li K, Wang D, Li S, Ning S, Yang H, Shi W, Liu Z, Chen Y
Scientific reports 2017 Mar 15;7:44275
Scientific reports 2017 Mar 15;7:44275
Methylation of SLFN11 is a marker of poor prognosis and cisplatin resistance in colorectal cancer.
He T, Zhang M, Zheng R, Zheng S, Linghu E, Herman JG, Guo M
Epigenomics 2017 Jun;9(6):849-862
Epigenomics 2017 Jun;9(6):849-862
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, Li Y, Wang X, Meng Y, Zhu M, Ma X, Huang C, Wu R, Xie C, Geng S, Wu J, Zhong C, Han H
The Journal of nutritional biochemistry 2017 Jun;44:80-91
The Journal of nutritional biochemistry 2017 Jun;44:80-91
ω-3 free fatty acids and all-trans retinoic acid synergistically induce growth inhibition of three subtypes of breast cancer cell lines.
Lin G, Zhu S, Wu Y, Song C, Wang W, Zhang Y, Chen YL, He Z
Scientific reports 2017 Jun 7;7(1):2929
Scientific reports 2017 Jun 7;7(1):2929
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Chen Y, Wang XQ, Zhang Q, Zhu JY, Li Y, Xie CF, Li XT, Wu JS, Geng SS, Zhong CY, Han HY
Nutrients 2017 Jun 3;9(6)
Nutrients 2017 Jun 3;9(6)
Methylation of DACT2 promotes breast cancer development by activating Wnt signaling.
Li J, Zhang M, He T, Li H, Cao T, Zheng L, Guo M
Scientific reports 2017 Jun 12;7(1):3325
Scientific reports 2017 Jun 12;7(1):3325
Effects of digoxin on cell cycle, apoptosis and NF-κB pathway in Burkitt's lymphoma cells and animal model.
Wang T, Xu P, Wang F, Zhou D, Wang R, Meng L, Wang X, Zhou M, Chen B, Ouyang J
Leukemia & lymphoma 2017 Jul;58(7):1673-1685
Leukemia & lymphoma 2017 Jul;58(7):1673-1685
Estrogen receptor-α36 is involved in icaritin induced growth inhibition of triple-negative breast cancer cells.
Wang X, Zheng N, Dong J, Wang X, Liu L, Huang J
The Journal of steroid biochemistry and molecular biology 2017 Jul;171:318-327
The Journal of steroid biochemistry and molecular biology 2017 Jul;171:318-327
Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.
Sheng X, You Q, Zhu H, Chang Z, Li Q, Wang H, Wang C, Wang H, Hui L, Du C, Xie X, Zeng R, Lin A, Shi D, Ruan K, Yan J, Gao GF, Shao F, Hu R
PLoS pathogens 2017 Jul;13(7):e1006534
PLoS pathogens 2017 Jul;13(7):e1006534
Dalbinol, a rotenoid from Amorpha fruticosa L., exerts anti-proliferative activity by facilitating β-catenin degradation in hepatocellular carcinoma cells.
Zhu X, Wu X, Cheng J, Liao H, Di X, Li L, Li R, Zhou Y, Zhang X
Oncotarget 2017 Jul 18;8(29):47755-47766
Oncotarget 2017 Jul 18;8(29):47755-47766
Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.
Hu YH, Chen Q, Lu YX, Zhang JM, Lin C, Zhang F, Zhang WJ, Li XM, Zhang W, Li XN
Oncotarget 2017 Jul 11;8(28):46191-46203
Oncotarget 2017 Jul 11;8(28):46191-46203
Galangin suppresses human osteosarcoma cells: An exploration of its underlying mechanism.
Yang Z, Li X, Han W, Lu X, Jin S, Yang W, Li J, He W, Qian Y
Oncology reports 2017 Jan;37(1):435-441
Oncology reports 2017 Jan;37(1):435-441
H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells.
Zhang Y, Xu C, Gu D, Wu M, Yan B, Xu Z, Wang Y, Liu H
Stem cells (Dayton, Ohio) 2017 Jan;35(1):222-235
Stem cells (Dayton, Ohio) 2017 Jan;35(1):222-235
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Yang J, Qiao L, Zeng Z, Wang J, Zhu T, Wei J, Wu M, Ye S, Huang X, Ma D, Liu R, Gao Q
Toxicology letters 2017 Jan 4;265:131-139
Toxicology letters 2017 Jan 4;265:131-139
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
Xue C, Wang C, Sun Y, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Ma X, Peng J, Liu K
Oncotarget 2017 Jan 31;8(5):8622-8632
Oncotarget 2017 Jan 31;8(5):8622-8632
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
Mao X, Li P, Wang Y, Liang Z, Liu J, Li J, Jiang Y, Bao G, Li L, Zhu B, Ren Y, Zhao X, Zhang J, Liu Y, Yang J, Liu P
Cell death & disease 2017 Jan 12;8(1):e2546
Cell death & disease 2017 Jan 12;8(1):e2546
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, Li Y, Chen Y, Wang X, Meng Y, Zhu M, Wu R, Huang C, Ma X, Geng S, Wu J, Zhong C
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Huang T, Xiao Y, Yi L, Li L, Wang M, Tian C, Ma H, He K, Wang Y, Han B, Ye X, Li X
Scientific reports 2017 Feb 6;7:38524
Scientific reports 2017 Feb 6;7:38524
Circular RNA 0000096 affects cell growth and migration in gastric cancer.
Li P, Chen H, Chen S, Mo X, Li T, Xiao B, Yu R, Guo J
British journal of cancer 2017 Feb 28;116(5):626-633
British journal of cancer 2017 Feb 28;116(5):626-633
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway.
Zang MD, Hu L, Fan ZY, Wang HX, Zhu ZL, Cao S, Wu XY, Li JF, Su LP, Li C, Zhu ZG, Yan M, Liu BY
Journal of translational medicine 2017 Feb 27;15(1):52
Journal of translational medicine 2017 Feb 27;15(1):52
Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells.
Liang Z, Li W, Liu J, Li J, He F, Jiang Y, Yang L, Li P, Wang B, Wang Y, Ren Y, Yang J, Luo Z, Vaziri C, Liu P
Scientific reports 2017 Feb 2;7:41776
Scientific reports 2017 Feb 2;7:41776
TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway.
Xu G, Guo Y, Xu D, Wang Y, Shen Y, Wang F, Lv Y, Song F, Jiang D, Zhang Y, Lou Y, Meng Y, Yang Y, Kang Y
Scientific reports 2017 Feb 16;7:42411
Scientific reports 2017 Feb 16;7:42411
Rhodium (II) complex with 2-benzoylpyridine, a novel potential chemotherapeutic drug, induces cell cycle arrest and apoptosis in HepG2 cells.
Wang X, Li Y, Lin M, Jin J, Huang Z
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2017 Dec;30(6):903-915
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2017 Dec;30(6):903-915
MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling.
Tang H, Lei CT, Ye C, Gao P, Wan C, Chen S, He FF, Wang YM, Su H, Zhang C
Journal of cellular and molecular medicine 2017 Dec;21(12):3435-3444
Journal of cellular and molecular medicine 2017 Dec;21(12):3435-3444
GRP78 positively regulates estrogen‑stimulated cell growth mediated by ER‑α36 in gastric cancer cells.
Fu Z, Wang X, Zhou H, Li Y, Chen Y, Wang Z, Liu L
Molecular medicine reports 2017 Dec;16(6):8329-8334
Molecular medicine reports 2017 Dec;16(6):8329-8334
Knockdown of Rhotekin 2 expression suppresses proliferation and induces apoptosis in colon cancer cells.
Pang X, Li R, Shi D, Pan X, Ma C, Zhang G, Mu C, Chen W
Oncology letters 2017 Dec;14(6):8028-8034
Oncology letters 2017 Dec;14(6):8028-8034
Shrimp miR-34 from Shrimp Stress Response to Virus Infection Suppresses Tumorigenesis of Breast Cancer.
Cui Y, Yang X, Zhang X
Molecular therapy. Nucleic acids 2017 Dec 15;9:387-398
Molecular therapy. Nucleic acids 2017 Dec 15;9:387-398
Effects of high-intensity focused ultrasound on cisplatin-resistant human lung adenocarcinoma in vitro and in vivo.
Zhang T, Chen L, Zhang S, Xu Y, Fan Y, Zhang L
Acta biochimica et biophysica Sinica 2017 Dec 1;49(12):1092-1098
Acta biochimica et biophysica Sinica 2017 Dec 1;49(12):1092-1098
Downregulation of USP32 inhibits cell proliferation, migration and invasion in human small cell lung cancer.
Hu W, Wei H, Li K, Li P, Lin J, Feng R
Cell proliferation 2017 Aug;50(4)
Cell proliferation 2017 Aug;50(4)
Fangchinoline suppresses the proliferation, invasion and tumorigenesis of human osteosarcoma cells through the inhibition of PI3K and downstream signaling pathways.
Li X, Yang Z, Han W, Lu X, Jin S, Yang W, Li J, He W, Qian Y
International journal of molecular medicine 2017 Aug;40(2):311-318
International journal of molecular medicine 2017 Aug;40(2):311-318
Efficient expression of stable recombinant human insulin-like growth factor-1 fusion with human serum albumin in Chinese hamster ovary cells.
Wan A, Xu D, Liu K, Peng L, Cai Y, Chen Y, He Y, Yang J, Jin J, Li H
Preparative biochemistry & biotechnology 2017 Aug 9;47(7):678-686
Preparative biochemistry & biotechnology 2017 Aug 9;47(7):678-686
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
Sun HJ, Xu DY, Sun YX, Xue T, Zhang CX, Zhang ZX, Lin W, Li KX
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
GOLPH3 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in epithelial ovarian cancer.
Sun J, Yang X, Zhang R, Liu S, Gan X, Xi X, Zhang Z, Feng Y, Sun Y
Cancer medicine 2017 Apr;6(4):834-844
Cancer medicine 2017 Apr;6(4):834-844
The role of MIF, cyclinD1 and ERK in the development of pulmonary hypertension in broilers.
Li H, Wang Y, Chen L, Han L, Li L, He H, Li Y, Huang N, Ren H, Pei F, Li G, Cheng J, Wang W
Avian pathology : journal of the W.V.P.A 2017 Apr;46(2):202-208
Avian pathology : journal of the W.V.P.A 2017 Apr;46(2):202-208
Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.
Quan Z, He Y, Luo C, Xia Y, Zhao Y, Liu N, Wu X
Cellular signalling 2017 Apr;32:48-58
Cellular signalling 2017 Apr;32:48-58
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Zhu JY, Yang X, Chen Y, Jiang Y, Wang SJ, Li Y, Wang XQ, Meng Y, Zhu MM, Ma X, Huang C, Wu R, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Phytotherapy research : PTR 2017 Apr;31(4):680-688
GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis.
Wang X, Liu B, Xu Q, Sun H, Shi M, Wang D, Guo M, Yu J, Zhao C, Feng B
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2017 Apr;25(2):270-278
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2017 Apr;25(2):270-278
The Antitumor Effect of DYC-279 on Human Hepatocellular Carcinoma HepG2 Cells.
Junyan P, Shujuan Y, Shulin G, Yan C, Xia X
Pharmacology 2016;97(3-4):177-83
Pharmacology 2016;97(3-4):177-83
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Wang D, Wang D, Wang N, Long Z, Ren X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer.
Chen S, Sun KX, Feng MX, Sang XB, Liu BL, Zhao Y
Drug design, development and therapy 2016;10:1225-32
Drug design, development and therapy 2016;10:1225-32
Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib.
Wei WJ, Shen CT, Song HJ, Qiu ZL, Luo QY
Oncology reports 2016 Sep;36(3):1576-84
Oncology reports 2016 Sep;36(3):1576-84
Berberine enhances the anti‑tumor activity of tamoxifen in drug‑sensitive MCF‑7 and drug‑resistant MCF‑7/TAM cells.
Wen C, Wu L, Fu L, Zhang X, Zhou H
Molecular medicine reports 2016 Sep;14(3):2250-6
Molecular medicine reports 2016 Sep;14(3):2250-6
Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway.
Feng T, Zheng L, Liu F, Xu X, Mao S, Wang X, Liu J, Lu Y, Zhao W, Yu X, Tang W
Oncotarget 2016 Sep 6;7(36):58381-58395
Oncotarget 2016 Sep 6;7(36):58381-58395
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Wang Y, Zhang XN, Xie WH, Zheng YX, Cao JP, Cao PR, Chen QJ, Li X, Sun CD
Nutrients 2016 Sep 27;8(10)
Nutrients 2016 Sep 27;8(10)
Knockdown of USP39 induces cell cycle arrest and apoptosis in melanoma.
Zhao Y, Zhang B, Lei Y, Sun J, Zhang Y, Yang S, Zhang X
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):13167-13176
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):13167-13176
Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma.
Zhan L, Cao H, Wang G, Lyu Y, Sun X, An J, Wu Z, Huang Q, Liu B, Xing J
Oncotarget 2016 Oct 4;7(40):65001-65011
Oncotarget 2016 Oct 4;7(40):65001-65011
Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance.
Zhao Y, Huan ML, Liu M, Cheng Y, Sun Y, Cui H, Liu DZ, Mei QB, Zhou SY
Scientific reports 2016 Oct 12;6:35267
Scientific reports 2016 Oct 12;6:35267
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Yuan S, Wen J, Cheng J, Shen W, Zhou S, Yan W, Shen L, Luo A, Wang S
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
Li H, Zhou F, Du W, Dou J, Xu Y, Gao W, Chen G, Zuo X, Sun L, Zhang X, Yang S
Biotechnology and applied biochemistry 2016 May;63(3):328-33
Biotechnology and applied biochemistry 2016 May;63(3):328-33
LSD1 is Required for Hair Cell Regeneration in Zebrafish.
He Y, Tang D, Cai C, Chai R, Li H
Molecular neurobiology 2016 May;53(4):2421-34
Molecular neurobiology 2016 May;53(4):2421-34
The effects of the 5-HT2A receptor antagonist sarpogrelate hydrochloride on chronic hypoxic pulmonary hypertension in rats.
Geng J, Fan FL, He S, Liu Y, Meng Y, Tian H, Zhang D, Ma Q, Zhang JB, Tian HY
Experimental lung research 2016 May;42(4):190-8
Experimental lung research 2016 May;42(4):190-8
The AhR is involved in the regulation of LoVo cell proliferation through cell cycle-associated proteins.
Yin J, Sheng B, Han B, Pu A, Yang K, Li P, Wang Q, Xiao W, Yang H
Cell biology international 2016 May;40(5):560-8
Cell biology international 2016 May;40(5):560-8
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Chen S, Sun KX, Liu BL, Zong ZH, Zhao Y
Oncotarget 2016 May 10;7(19):27538-51
Oncotarget 2016 May 10;7(19):27538-51
Down-regulation of dihydrofolate reductase inhibits the growth of endothelial EA.hy926 cell through induction of G1 cell cycle arrest via up-regulating p53 and p21(waf1/cip1) expression.
Fei Z, Gao Y, Qiu M, Qi X, Dai Y, Wang S, Quan Z, Liu Y, Ou J
Journal of clinical biochemistry and nutrition 2016 Mar;58(2):105-13
Journal of clinical biochemistry and nutrition 2016 Mar;58(2):105-13
miR-194 inhibits the proliferation, invasion, migration, and enhances the chemosensitivity of non-small cell lung cancer cells by targeting forkhead box A1 protein.
Zhu X, Li D, Yu F, Jia C, Xie J, Ma Y, Fan S, Cai H, Luo Q, Lv Z, Fan L
Oncotarget 2016 Mar 15;7(11):13139-52
Oncotarget 2016 Mar 15;7(11):13139-52
MicroRNA-655-3p functions as a tumor suppressor by regulating ADAM10 and β-catenin pathway in Hepatocellular Carcinoma.
Wu G, Zheng K, Xia S, Wang Y, Meng X, Qin X, Cheng Y
Journal of experimental & clinical cancer research : CR 2016 Jun 4;35(1):89
Journal of experimental & clinical cancer research : CR 2016 Jun 4;35(1):89
The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR.
Zhao S, Cao Y, Liu SB, Wang XA, Bao RF, Shu YJ, Hu YP, Zhang YJ, Jiang L, Zhang F, Liang HB, Li HF, Ma Q, Xu Y, Wang Z, Zhang YC, Chen L, Zhou J, Liu YB
Journal of experimental & clinical cancer research : CR 2016 Jun 18;35(1):97
Journal of experimental & clinical cancer research : CR 2016 Jun 18;35(1):97
Latcripin-13 domain induces apoptosis and cell cycle arrest at the G1 phase in human lung carcinoma A549 cells.
Wang J, Wan X, Gao Y, Zhong M, Sha L, Liu B, Zhang W, Tian L, Ruan W, Cao S, Huang M
Oncology reports 2016 Jul;36(1):441-7
Oncology reports 2016 Jul;36(1):441-7
High Expression of XRCC6 Promotes Human Osteosarcoma Cell Proliferation through the β-Catenin/Wnt Signaling Pathway and Is Associated with Poor Prognosis.
Zhu B, Cheng D, Li S, Zhou S, Yang Q
International journal of molecular sciences 2016 Jul 22;17(7)
International journal of molecular sciences 2016 Jul 22;17(7)
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway.
Zhang J, Wen X, Ren XY, Li YQ, Tang XR, Wang YQ, He QM, Yang XJ, Sun Y, Liu N, Ma J
Journal of experimental & clinical cancer research : CR 2016 Jul 11;35(1):109
Journal of experimental & clinical cancer research : CR 2016 Jul 11;35(1):109
GalNAc-T4 putatively modulates the estrogen regulatory network through FOXA1 glycosylation in human breast cancer cells.
Niang B, Jin L, Chen X, Guo X, Zhang H, Wu Q, Padhiar AA, Xiao M, Fang D, Zhang J
Molecular and cellular biochemistry 2016 Jan;411(1-2):393-402
Molecular and cellular biochemistry 2016 Jan;411(1-2):393-402
Keratinocyte Growth Factor Regulation of Aryl Hydrocarbon Receptor Activation in Colorectal Cancer Cells.
Yin J, Sheng B, Pu A, Han B, Yang K, Wang Q, Sun L, Yang H
Digestive diseases and sciences 2016 Feb;61(2):444-52
Digestive diseases and sciences 2016 Feb;61(2):444-52
miRNA-149* promotes cell proliferation and suppresses apoptosis by mediating JunB in T-cell acute lymphoblastic leukemia.
Fan SJ, Li HB, Cui G, Kong XL, Sun LL, Zhao YQ, Li YH, Zhou J
Leukemia research 2016 Feb;41:62-70
Leukemia research 2016 Feb;41:62-70
MicroRNA-101 targets von Hippel-Lindau tumor suppressor (VHL) to induce HIF1α mediated apoptosis and cell cycle arrest in normoxia condition.
Liu N, Xia WY, Liu SS, Chen HY, Sun L, Liu MY, Li LF, Lu HM, Fu YJ, Wang P, Wu H, Gao JX
Scientific reports 2016 Feb 4;6:20489
Scientific reports 2016 Feb 4;6:20489
Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma.
Wang XQ, Tang ZX, Yu D, Cui SJ, Jiang YH, Zhang Q, Wang J, Yang PY, Liu F
Oncotarget 2016 Feb 23;7(8):8823-38
Oncotarget 2016 Feb 23;7(8):8823-38
Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling.
Liu F, Zhang W, Yang F, Feng T, Zhou M, Yu Y, Yu X, Zhao W, Yi F, Tang W, Lu Y
Scientific reports 2016 Feb 16;6:21260
Scientific reports 2016 Feb 16;6:21260
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway.
Gao H, Sun B, Fu H, Chi X, Wang F, Qi X, Hu J, Shao S
Oncotarget 2016 Aug 16;7(33):53289-53298
Oncotarget 2016 Aug 16;7(33):53289-53298
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Geng S, Zheng Y, Meng M, Guo Z, Cao N, Ma X, Du Z, Li J, Duan Y, Du G
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways.
Jing H, Sun W, Fan J, Zhang Y, Yang J, Jia J, Li J, Guo J, Luo S, Zheng Y
Molecular medicine reports 2016 Apr;13(4):3009-16
Molecular medicine reports 2016 Apr;13(4):3009-16
RNA interference of Biot2 induces G1 phase arrest and apoptosis in mouse colorectal cancer cell line.
Zhou C, Zhang P, Xu GC, Wu DM, Liu RY, Zeng Q, Wang CT
Oncology research 2015;22(2):93-103
Oncology research 2015;22(2):93-103
Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway.
Zhang C, Zhang J, Li X, Sun N, Yu R, Zhao B, Yu D, Cheng Y, Liu Y
Evidence-based complementary and alternative medicine : eCAM 2015;2015:171356
Evidence-based complementary and alternative medicine : eCAM 2015;2015:171356
Pemetrexed induces G1 phase arrest and apoptosis through inhibiting Akt activation in human non small lung cancer cell line A549.
Wu DM, Zhang P, Xu GC, Tong AP, Zhou C, Lang JY, Wang CT
Asian Pacific journal of cancer prevention : APJCP 2015;16(4):1507-13
Asian Pacific journal of cancer prevention : APJCP 2015;16(4):1507-13
siRNA-mediated knockdown of JUB expression suppresses the proliferation of glioblastoma cells.
Ouyang H, Guo Z, Cheng Z, Guo Y
Cancer biomarkers : section A of Disease markers 2015;15(4):477-84
Cancer biomarkers : section A of Disease markers 2015;15(4):477-84
Lentivirus-mediated gene silencing of NOB1 suppresses non-small cell lung cancer cell proliferation.
Huang W, Zhong W, Xu J, Su B, Huang G, Du J, Liu Q
Oncology reports 2015 Sep;34(3):1510-6
Oncology reports 2015 Sep;34(3):1510-6
Doxorubicin-poly (ethylene glycol)-alendronate self-assembled micelles for targeted therapy of bone metastatic cancer.
Ye WL, Zhao YP, Li HQ, Na R, Li F, Mei QB, Zhao MG, Zhou SY
Scientific reports 2015 Sep 30;5:14614
Scientific reports 2015 Sep 30;5:14614
Low SFRP1 Expression Correlates with Poor Prognosis and Promotes Cell Invasion by Activating the Wnt/β-Catenin Signaling Pathway in NPC.
Ren XY, Zhou GQ, Jiang W, Sun Y, Xu YF, Li YQ, Tang XR, Wen X, He QM, Yang XJ, Liu N, Ma J
Cancer prevention research (Philadelphia, Pa.) 2015 Oct;8(10):968-77
Cancer prevention research (Philadelphia, Pa.) 2015 Oct;8(10):968-77
miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells.
He K, Tong D, Zhang S, Cai D, Wang L, Yang Y, Gao L, Chang S, Guo B, Song T, Li A, Huang C
International journal of oncology 2015 Oct;47(4):1528-36
International journal of oncology 2015 Oct;47(4):1528-36
Quercetin reverses experimental pulmonary arterial hypertension by modulating the TrkA pathway.
He Y, Cao X, Liu X, Li X, Xu Y, Liu J, Shi J
Experimental cell research 2015 Nov 15;339(1):122-34
Experimental cell research 2015 Nov 15;339(1):122-34
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Zhang Y, Zhang X, Huang J, Dong Q
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
Dai B, Wang W, Liu R, Wang H, Zhang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:227-33
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:227-33
MicroRNA-490-3P targets CDK1 and inhibits ovarian epithelial carcinoma tumorigenesis and progression.
Chen S, Chen X, Xiu YL, Sun KX, Zhao Y
Cancer letters 2015 Jun 28;362(1):122-30
Cancer letters 2015 Jun 28;362(1):122-30
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Xiao W, Jiang Y, Men Q, Yuan L, Huang Z, Liu T, Li W, Liu X
International journal of oncology 2015 Jan;46(1):360-8
International journal of oncology 2015 Jan;46(1):360-8
Knockdown of ANLN by lentivirus inhibits cell growth and migration in human breast cancer.
Zhou W, Wang Z, Shen N, Pi W, Jiang W, Huang J, Hu Y, Li X, Sun L
Molecular and cellular biochemistry 2015 Jan;398(1-2):11-9
Molecular and cellular biochemistry 2015 Jan;398(1-2):11-9
Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins.
Li X, Liu X, Xu Y, He Y, Liu J, Xie M
International journal of oncology 2015 Feb;46(2):677-84
International journal of oncology 2015 Feb;46(2):677-84
Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.
Chen X, Meng Q, Wang C, Liu Q, Sun H, Huo X, Sun P, Yang X, Peng J, Liu K
Pharmaceutical research 2015 Feb;32(2):538-48
Pharmaceutical research 2015 Feb;32(2):538-48
Capsaicin causes inactivation and degradation of the androgen receptor by inducing the restoration of miR-449a in prostate cancer.
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 60186-1-Ig(CCND1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using CCND1 antibody 60186-1-lg at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red).
- Sample type
- cell line
