CCND1

gene product
BCL1, D11S287E, PRAD1, U21B31
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008]
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Invitrogen Antibodies
28 antibodies
NSJ Bioreagents
20 antibodies
GeneTex
29 antibodies
Novus Biologicals
97 antibodies
Abgent
16 antibodies
antibodies-online
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OriGene
60 antibodies
Antibodies.com
4 antibodies
Acris Antibodies GmbH
41 antibodies
Enzo Life Sciences
3 antibodies
LifeSpan BioSciences, Inc.
406 antibodies
Cell Signaling Technology, Inc
6 antibodies
Boster Biological Technology
7 antibodies
R&D Systems
3 antibodies
Biorbyt
101 antibodies
Abnova Corporation
27 antibodies
Affinity Biosciences
8 antibodies
St John's Laboratory
13 antibodies
NovoPro Bioscience Inc.
3 antibodies
Signalway Antibody LLC
1 antibody
Aviva Systems Biology
13 antibodies
Arigo
6 antibodies
Proteintech Group
1 antibody
ProSci
10 antibodies
Bioworld Technology, Inc
3 antibodies
Spring Bioscience
8 antibodies
Creative Biolabs
69 antibodies
RabMAbs
7 antibodies
Abbexa
6 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
GenWay
13 antibodies
United States Biological
105 antibodies
MyBioSource
32 antibodies
BioLegend
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
FabGennix
18 antibodies
ABEOMICS Inc.
2 antibodies
Creative Diagnostics
10 antibodies
RayBiotech, Inc.
3 antibodies
Atlas Antibodies
1 antibody
EMD Millipore
6 antibodies
Abbiotec
4 antibodies
Sigma-Aldrich
5 antibodies
DB Biotech
1 antibody
Exalpha Biologicals, Inc.
1 antibody
Nordic BioSite
2 antibodies