Tissue expression
Cell line expression
Protein structure

CCND1

Cyclin D1
BCL1, D11S287E, PRAD1, U21B31 
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of human cancers. [provided by RefSeq, Dec 2019]
More gene data

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2419 antibodies from 54 providers.

Antibody properties

Applications

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
149 antibodies
NSJ Bioreagents
22 antibodies
GeneTex
29 antibodies
Novus Biologicals
108 antibodies
Boster Biological Technology
8 antibodies
Abgent
16 antibodies
antibodies-online
689 antibodies
OriGene
60 antibodies
Biorbyt
319 antibodies
Antibodies.com
4 antibodies
Acris Antibodies GmbH
41 antibodies
Enzo Life Sciences
3 antibodies
Cell Signaling Technology, Inc
6 antibodies
Cusabio Biotech Co., Ltd
15 antibodies
St John's Laboratory
39 antibodies
Proteintech Group
3 antibodies
R&D Systems
3 antibodies
Abnova Corporation
27 antibodies
Affinity Biosciences
8 antibodies
HUABIO Research
3 antibodies
NovoPro Bioscience Inc.
3 antibodies
Signalway Antibody LLC
1 antibody
Aviva Systems Biology
13 antibodies
Arigo
6 antibodies
FineTest Biotech
2 antibodies
Exalpha Biologicals, Inc.
1 antibody
ProSci
10 antibodies
Bioworld Technology, Inc
3 antibodies
Spring Bioscience
8 antibodies
Creative Biolabs
87 antibodies
RabMAbs
7 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
GenWay
13 antibodies
Cambridge Research Biochemicals
1 antibody
Everest Biotech
1 antibody
United States Biological
105 antibodies
Leading Biology
22 antibodies
MyBioSource
32 antibodies
MilliporeSigma / Merck KGaA
11 antibodies
BioLegend
1 antibody
Abbexa
46 antibodies
FabGennix
18 antibodies
ABEOMICS Inc.
2 antibodies
Creative Diagnostics
11 antibodies
RayBiotech, Inc.
3 antibodies
Atlas Antibodies
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
EMD Millipore
6 antibodies
Abbiotec
4 antibodies
DB Biotech
1 antibody
Nordic BioSite
2 antibodies
CPTAC
6 antibodies