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- Antibody Data
- Antigen structure
- References [574]
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- Product number
- 26939-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Cyclin D1 antibody
- Antibody type
- Polyclonal
- Description
- Cyclin D1 antibody (Cat. #26939-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CCT5 as a candidate biomarker in bladder cancer: functional validation and mechanistic clues.
Asiatic Acid Ameliorates MNNG-Induced Chronic Atrophic Gastritis by Inhibiting the Activation of the HRAS/PI3K/AKT/GSK3β Signaling Axis.
Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression.
TRIM35 inhibits endometrial cancer progression via ubiquitination and degradation of EIF3E.
Plasma-activated hydrogel promotes postoperative colonic anastomotic leak healing.
TFAP2A regulates SGPP2 transcription to promote lipid accumulation and activate the Wnt/β-catenin signaling pathway to promote malignant progression in lung adenocarcinoma.
Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation.
A new candidate tumor suppressor tRF-Ser inhibits gastric cancer progression by regulating the CNBP/HSPA8 axis.
CCT3-mediated regulation of XPO1/RB1 axis stability promotes cellular senescence and tumor progression in clear cell renal carcinoma.
The role of FPR3 in remodeling the immune microenvironment and lung metastasis of colon adenocarcinoma.
A multimodal ROS logic-gated therapeutic platform disrupts the vicious cycle of senescence to promote aged bone defect repair.
Design, synthesis and anti-bladder cancer activity of novel dihydroartemisinin-ibuprofen hybrids.
Pyrimethamine regulates m6A modification of CCND1 via METTL14/YTHDF2 to inhibit hepatocellular carcinoma.
QiShenYiQi dripping pills ameliorate post-myocardial infarction cardiac fibrosis via modulation of the cAMP/Rap1 and PI3K/Akt signaling pathways.
SIGLEC15 modulates the immunosuppressive microenvironment and suppresses malignant phenotypes in triple-negative breast cancer.
Time-resolved multiomics profiling reveals chromatin O-GlcNAc modification promotes senescence-associated transcriptional program.
Cyclin D1/D2-CDK4 Drives Cell Migration by Orchestrating Cytoskeletal Dynamics Through a TGFβ-FAK-Rac1 Axis.
Inhibition of the RORC/GPX4 mediated ferroptosis regulatory axis suppresses tumor growth and alleviates enzalutamide resistance in prostate cancer.
The prognostic value of miR-323b-5p in non-small cell lung cancer and its mechanism of targeting IL1A in regulating the proliferation and cell cycle of non-small cell lung cancer cells.
TRV130 inhibits colon cancer progression via suppressing the Hedgehog signaling pathway: in vitro and in vivo evidence.
Mechanisms underlying the therapeutic effects of Amygdalin in treating Cervical Cancer based on multi-omics analysis.
Decoding the healing secrets of Gegenqinlian decoction: A promising approach to radiation-induced intestinal injury.
Genome-wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer.
SREBP1 knockdown triggers ferroptosis by suppressing the Nrf2-XCT/GPX4 axis in ovarian cancer.
m6A methylation-modified ETV1 drives multiple myeloma progression and M2 polarization of tumor-associated macrophage through transcriptional activation of RBMS1.
DNA Methylation-Regulated FAM107A Affects Colorectal Carcinogenesis by Inhibiting FOXM1.
Genetic and pharmaceutical manipulation of H3K9 methyltransferase Suv39h1 promotes liver regeneration by unleashing HMGB2 transcription.
Gut microbial metabolite, sphingosine-1-phosphate (S1P), drives mesangial cell phenotypic transformation and accelerates progression of IgA nephropathy via CCL2-MET-FAK pathway.
LTF regulates glioblastoma progression and temozolomide resistance via the NF-κB signaling pathway.
TIMM8A-TIMM13 Complex Exerts Oncogenic Functions in Lung Cancer.
Exosome-Delivered circFOXP1 Upregulates Autophagy and Promotes Hepatocellular Carcinoma Progression Through Its Encoded p196 Protein Targeting the KHDRBS3/ULK1 Axis.
Overexpression of MCM3 as a prognostic biomarker correlated with cell proliferation, cell cycle and immune regulation in hepatocellular carcinoma.
NCAPG promotes the malignant progression of endometrioid cancer through LEF1/SEMA7A/PI3K-AKT.
PSMD12 promotes hepatocellular carcinoma progression by stabilizing CDK1.
Gen-miR-5 derived from Gentianella acuta inhibits PFKP to prevent fibroblast activation and alleviate myocardial fibrosis.
Triptolide alleviates psoriasis through inhibiting the Wnt5a/β-Catenin signaling pathway.
Exploration of the Mechanism of Action of Dendrobium officinale in the Treatment of Liver Cancer Based on Network Pharmacology, Molecular Docking and in vitro Validation.
Triflupromazine and tranylcypromine alleviate primary cisplatin resistance in lung adenocarcinoma by promoting LDHA-mediated AMBRA1 ubiquitination.
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
Mechanism of ferroptosis in hypoxia-induced pulmonary vascular remodeling in hypoxia pulmonary hypertension: a study based on the ACE2-Ang-(1-7)-Mas axis.
CHD4 drives gastric cancer metastasis via MYH9/GSK3β/β-catenin axis and WNT/EMT pathway activation.
NCAPH-YAP1 interaction promotes breast cancer stemness and tumor progression.
Exosomal miR-3529-3p increases the sensitivity of trastuzumab via Wnt/β-catenin signaling pathway by targeting HOOK3.
Kuwanon A Targeted YWHAB in Hepatocellular Carcinoma Cells to Inhibit the Raf/MEK/ERK Signaling Pathway.
Transplanting neural stem cells overexpressing miRNA-21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28-let-7 signaling pathway.
Chidamide Accelerates the Death of Senescence-Like Diffuse Large B-Cell Lymphoma Cells With TP53 Mutation Induced by Doxorubicin.
Canagliflozin inhibits hepatic stellate cells activation and proliferation by inhibiting PP2A-mediated β-catenin dephosphorylation to attenuate hepatic fibrosis.
TRIM21 as a potential prognostic biomarker and therapeutic target affects the growth of pancreatic cancer.
CRL4(DCAF12) regulation of MCMBP ensures optimal licensing of DNA replication.
Pan-cancer analysis of role of LOXL4 and experiment validation in osteosarcoma.
RSL3 promotes PARP1 apoptotic functions by distinct mechanisms during ferroptosis.
Hexokinase HK2 regulates the MYH9-GSK3β/β-catenin axis to promote myocardial regeneration and repair after injury.
miR-423-3p inhibits CTNNBIP1/WNT preventing hyperandrogenic polycystic ovary syndrome†.
Centromere protein I facilitates breast cancer tumorigenesis and disease progression through modulation of Wnt/β-Catenin signaling.
FAM111B enhances glycolysis and promotes metastasis of prostate cancer by upregulating LDHA.
A synergy of CD133 overexpression and TGF-β supplementation in tumorigenesis of ovarian cancer cell lines in a three-dimensional sphere forming model.
Polystyrene nanoplastics impair endometrial decidualization via cell cycle arrest and JNK-MAPK pathway-mediated oxidative stress in early pregnant mice.
O-GlcNAcylation of PRDX1 enhances its stability and promotes liver cancer progression via activating LRP6-mediated Wnt signaling.
EBV-miR-BART5-3p promotes the proliferation of Burkitt lymphoma cells via glycolytic pathway.
MYST1-Mediated Lysine Acetylation Stabilizes KLF4 to Promote Intimal Hyperplasia.
Histone demethylase KDM9 activates the CCND1/AKT pathway to promote the malignant progression of gliomas through interaction with BRD2.
tiRNA: An efficient and controllable gene silencing technology via translation inhibition.
The local anesthetic, lidocaine, suppresses the growth of colon cancer SW480 cells by decreasing the voltage-gated sodium channel subunit Na(v)1.5.
Radix Rehmanniae Praeparata Extract Enhances Liver Regeneration Through AMPK-Driven Metabolic Reprogramming.
Dual-Targeted Biomimetic Nanoparticles for Enhanced Delivery of Polyphyllin B Synergistically Induce Ferroptosis and Immunogenic Cell Death in Gastric Cancer.
Analysis of differential transcriptome expression reveals that ISG15 provides support for embryo development by promoting angiogenesis in porcine mesometrium.
PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it.
AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep.
Arjunolic acid inhibits Wnt3a-mediated macrophage M2 polarization to suppress osteosarcoma progression.
SERCA2 dysfunction accelerates angiotensin II-induced aortic aneurysm and atherosclerosis by induction of oxidative stress in aortic smooth muscle cells.
CENPF (+) cancer cells promote malignant progression of early-stage TP53 mutant lung adenocarcinoma.
NPC1L1 Drives Osteoporosis by Activating the C/EBPα/Cyp27a1/27-Hydroxycholesterol Axis: A Novel Therapeutic Target for Bone Loss.
Deuterium-depleted water inhibits the malignant progression of colorectal cancer cells by modulating oxidative stress.
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β-Catenin Signaling Pathway.
Three-Dimensional Bioprinted Scaffolds Loaded with Multifunctional Magnesium-Based Metal-Organic Frameworks Improve the Senescence Microenvironment Prompting Aged Bone Defect Repair.
Cytohesin-4/ARF6 facilitates the progression of acute myeloid leukemia through activating PIK3R5/PI3K/AKT pathway.
Hepatic micropeptide modulates mitochondrial RNA processing machinery in hepatocellular carcinoma.
Mechanism of berbamine-mediated DNA damage in synovial fibroblasts to alleviate rheumatoid arthritis.
KLF4 mediates the contradictory effects of phenylethyl isothiocyanate in gastric cancer intervention.
PELI2 inhibits colorectal cancer development through MAPK signaling pathway.
YY1/HIF-1α/mROS positive-feedback loop exacerbates glomerular mesangial cell proliferation in mouse early diabetic kidney disease.
Phytochemical profile of bioactive Siraitia grosvenorii root fraction and its potential against nonsmall cell lung cancer in vitro and in vivo.
METTL3 regulates Ambra1 expression in an m6A-YTHDF2-dependent manner to promote mantle cell lymphoma progression.
Circular RNA circLIMK1-005 promotes the progression of lung adenocarcinoma by interacting with RPA1 protein to activate CDK4 signaling.
Lycorine hydrochloride interferes with energy metabolism to inhibit chemoresistant glioblastoma multiforme cell growth through suppressing PDK3.
Role of semaphorin7A in epithelial-mesenchymal transition and proliferative vitreoretinopathy.
Taraxasterol regulates p53 transcriptional activity to inhibit pancreatic cancer by inducing MDM2 ubiquitination degradation.
Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
FAM49B drives colorectal cancer progression by stabilizing c-Myc through NEK9 phosphorylation.
RNF112, whose transcription is regulated by KLF4, inhibits colorectal cancer growth via promoting ubiquitin-dependent degradation of NAA40.
Shanyao regulates the PI3K/AKT/P21 pathway to promote oogonial stem cell proliferation and stemness restoration to alleviate premature ovarian insufficiency.
Ubiquitin-conjugating enzyme E2T confers chemoresistance of colorectal cancer by enhancing the signal propagation of Wnt/β-catenin pathway in an ERK-dependent manner.
Identification of KRT16 and ANXA10 as cell cycle regulation genes for lung adenocarcinoma based on self-transcriptome sequencing of surgical samples and TCGA public data mining.
TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination.
Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma.
Zuogui pills ameliorate chemotherapy-induced ovarian aging by improving stemness, regulating cell cycle and reducing apoptosis of oogonial stem cells via the Notch1/Nrf2 pathway.
Regulation of the β‑catenin/LEF‑1 pathway by the siRNA knockdown of RUVBL1 expression inhibits breast cancer cell proliferation, migration and invasion.
Ilicicolin C suppresses the progression of prostate cancer by inhibiting PI3K/AKT/mTOR pathway.
Synthesis of novel deuterated EGFR/ALK dual-target inhibitors and their activity against non-small cell lung cancer.
The Unveiled Novel regulator of Adeno-associated virus production in HEK293 cells.
Unbalanced occlusal loading elicited remodeling responses in growing rat temporomandibular joints and Notch1/Hes1 signaling pathway expression.
Aqueous extract of Cornus officinalis alleviate NAFLD via protecting hepatocytes proliferation through regulation of the tricarboxylic acid cycle.
B7-H3 enhances the malignant phenotype of colorectal cancer by activating the Wnt/β-catenin pathway mediated by CYP1B1.
TTK Defines a High-Risk Oral Squamous Cell Carcinoma Subtype Through Dual mTORC1/NF-κB Activation.
Exosome-mediated perturbation of the immune-bone metabolism axis: a mechanistic investigation into bone loss in a simulated microgravity environment.
Bovine tubulin cofactor D (TBCD) disrupts tubulin dimers and inhibits tumor growth via the TNF-α signaling pathways-mediated ROS production.
The suprachiasmatic nucleus regulates brown fat thermogenesis in male mice through an adrenergic receptor ADRB3-S100B signaling pathway.
Terpine-4-ol alleviates lipopolysaccharide-induced intestinal injury in weaned piglets by regulating intestinal epithelial cell homeostasis via the Wnt/β-catenin signaling pathway.
The RNA-binding protein Quaking modulates cell proliferation through the SFRP1 mediated Wnt signaling pathway in NIH3T3 fibroblasts.
UBE2M inhibits neoplastic cell proliferation via MKK7-JNK-EGR1 axis in melanoma.
Multi-omics analysis reveals that ALYREF-mediated m(5)C modification promotes platinum resistance in ovarian cancer via the NSUN2/ALYREF/LGR4 axis.
LGR5 interacts with HSP90AB1 to mediate enzalutamide resistance by activating the WNT/β-catenin/AR axis in prostate cancer.
Bruceine D promotes TNBC regression by inhibiting M2-like tumor-associated macrophage polarization induced Wnt3a/β-catenin pathway.
Targeting TRIM15-mediated Axin1 depolymerization suppresses Wnt signaling and inhibits colorectal cancer growth.
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
Shikonin inhibits multiple tumor malignant phenotypes and is associated with Hedgehog pathway downregulation in lung adenocarcinoma.
Targeting intrinsically disordered nuclear protein 1 (NUPR1) with single-domain antibodies alleviates triple-negative breast cancer (TNBC) progression in vivo.
GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.
Evaluation of the clinical characteristics and potentially prognostic factors in HER2-positive breast cancer.
Synthesis, molecular modeling, biological and pharmacokinetic evaluation of hydroxy pyrimidinones and pyrimidinediones as novel LDHA inhibitors.
Repetitive unidirectional spinal tactile stimulation engages microglial Bmal1 pathways to promote synaptic remodeling in the mPFC of adolescent VPA-exposed mice.
Knockdown of MiD49 and MiD51 alleviates collagen-induced arthritis and suppresses mitophagy and fatty acid oxidation (FAO) in rheumatoid arthritis fibroblast-like synoviocytes.
FTO curbs trophoblast cell biological behaviors through repressing ALDH1A1 expression.
Dujieqing decoction suppresses multiple myeloma growth by inhibiting the Wnt/β-catenin pathway.
The LINC01315-encoded small protein YAPer-ORF competes with PRP4k to hijack YAP signaling to aberrantly promote cell growth.
NUTF2 Promotes Proliferation of Oral Squamous Cell Carcinoma Through PI3K/AKT Signaling Pathway.
PIMREG modulation of PI3K/Akt pathway enhances sorafenib resistance in Huh7 cells.
SETD2 drives METTL14-mediated m(6)A to suppress Piezo1 Attenuation and activate TGM2 to promote pulmonary hypertension.
Non-SMC condensin I complex subunit H promotes cell proliferation and inhibits cell apoptosis of clear cell renal cell carcinoma by activating the PI3K/AKT pathway.
Overexpression of FOS enhances the malignant potential of eutopic endometrial stromal cells in patients with endometriosis‑associated ovarian cancer.
Design, synthesis and antitumor activity evaluation of novel modified 18β-glycyrrhetinate derivatives as PPARγ agonists.
EGCG inhibits tobacco smoke-promoted proliferation of lung cancer cells through targeting CCL5.
GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy.
Simultaneous cyclin D1 overexpression and p27(kip1) knockdown enable robust Müller glia cell cycle reactivation in uninjured mouse retina.
THBS2-producing matrix CAFs promote colorectal cancer progression and link to poor prognosis via the CD47-MAPK axis.
EPHA5 promotes cell proliferation and inhibits apoptosis in Follicular Thyroid Cancer via the STAT3 signaling pathway.
A novel feedback regulation loop of METTL11A-MAFG-NPL4 promotes bladder cancer cell proliferation and tumor progression.
CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy.
Pulsatilla saponin D inhibited the growth of osteosarcoma by regulating the JNK/ATF3 signaling pathway.
The anti-tumor activity of tangeretin in esophageal squamous cell carcinoma by inhibiting GLI2-mediated transcription of GPNMB.
ADAR1 plays a protective role in proximal tubular cells under high glucose conditions by attenuating the PI3K/AKT/mTOR signaling pathway.
KRT80 Promotes Lung Adenocarcinoma Progression and Serves as a Substrate for VCP.
Apolipoprotein L3 inhibits breast cancer proliferation and modulates cell cycle via the P53 pathway.
TXNDC12 inhibits pancreatic tumor cells ferroptosis by regulating GSH/GGT7 and promotes its growth and metastasis.
PSAT1 mediated EMT of colorectal cancer cells by regulating Pl3K/AKT signaling pathway.
B4 suppresses lymphoma progression by inhibiting fibroblast growth factor binding protein 1 through intrinsic apoptosis.
Development of an anoikis-related gene signature and prognostic model for predicting the tumor microenvironment and response to immunotherapy in colorectal cancer.
Comprehensive analysis of ferroptosis-related genes indicates that TRIM46 is a novel biomarker and promotes the progression of ovarian cancer via modulating ferroptosis and Wnt signaling pathway.
MK8722 initiates early-stage autophagy while inhibiting late-stage autophagy via FASN-dependent reprogramming of lipid metabolism.
The long noncoding RNA MIR4435-2HG enhances the migration, promotion, and glycolysis of nonsmall cell lung cancer cells by targeting the miR-371a-5p/SOX2/PI3K/Akt axis.
A potent new-scaffold androgen receptor antagonist discovered on the basis of a MIEC-SVM model.
Alternative splicing of ALDOA confers tamoxifen resistance in breast cancer.
TTYH3 Promotes Cervical Cancer Progression by Activating the Wnt/β-Catenin Signaling Pathway.
α-Ketoglutarate promotes cardiomyocyte proliferation and heart regeneration after myocardial infarction.
PSMD11 promotes the proliferation of hepatocellular carcinoma by regulating the ubiquitination degradation of CDK4.
USP22 is required for human endometrial stromal cell proliferation and decidualization by deubiquitinating FoxM1.
SFRP1 reduces neutrophil infiltration and inhibits the Wnt/β-catenin pathway to alleviate oral submucous fibrosis.
MIA3 promotes the degradation of GSH (glutathione) by binding to CHAC1, thereby promoting the progression of hepatocellular carcinoma.
Evaluation of 3-O-β-D-galactosylated resveratrol-loaded polydopamine nanoparticles for hepatocellular carcinoma treatment.
Rho GTPase activating protein 11A promotes tongue squamous cell carcinoma proliferation and is a transcriptional target of forkhead box M1.
EREG silencing inhibits tumorigenesis via inactivating ERK/p38 MAPK pathway in pancreatic ductal adenocarcinoma.
The expression and role of SUZ12 in lung adenocarcinoma.
N-acetylgalactosaminyltransferase GALNT6 is a potential therapeutic target of clear cell renal cell carcinoma progression.
Zuogui Pills alleviate cyclophosphamide-induced ovarian aging by reducing oxidative stress and restoring the stemness of oogonial stem cells through the Nrf2/HO-1 signaling pathway.
PTPN11 is a potential biomarker for type 2 diabetes mellitus complicated with colorectal cancer.
A quinoline-2-thione derivative as a novel chemotherapy drug candidate displays anti-tumor activity in vitro and in vivo.
DEAD/H-box helicase 11 is transcriptionally activated by Yin Yang-1 and accelerates oral squamous cell carcinoma progression.
NSUN2 regulates Wnt signaling pathway depending on the m5C RNA modification to promote the progression of hepatocellular carcinoma.
Hepatocyte-Specific HuR Protects Against Acetaminophen-Induced Liver Injury in Mice.
Talaketides A-G, linear polyketides with prostate cancer cytotoxic activity from the mangrove sediment-derived fungus Talaromyces sp. SCSIO 41027.
Sterile Alpha Motif Domain-Containing 5 Suppresses Malignant Phenotypes and Tumor Growth in Breast Cancer: Regulation of Polo-Like Kinase 1 and c-Myc Signaling in a Xenograft Model.
ZNF652 exerts a tumor suppressor role in lung cancer by transcriptionally downregulating cyclin D3.
Erianin inhibits the progression of DDP-resistant lung adenocarcinoma by regulating the Wnt/β-catenin pathway and activating the caspase-3 for apoptosis in vitro and in vivo.
Dapagliflozin suppressed gastric cancer growth via regulating OTUD5 mediated YAP1 deubiquitination.
Inhibition of mitochondrial OMA1 ameliorates osteosarcoma tumorigenesis.
Dihydroartemisinin-driven selective anti-lung cancer proliferation by binding to EGFR and inhibition of NRAS signaling pathway-induced DNA damage.
Allosteric SHP2 inhibition enhances regorafenib's effectiveness in colorectal cancer treatment.
MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer.
Combined SET7/9 and CDK4 inhibition act synergistically against osteosarcoma.
A novel disulfide death-related genes prognostic signature identifies the role of IPO4 in glioma progression.
Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping.
METTL3-mediated m(6)A modification of SOX4 regulates osteoblast proliferation and differentiation via YTHDF3 recognition.
The mechanism of Chebulae Fructus Immaturus promote diabetic wound healing based on network pharmacology and experimental verification.
YTHDF1 Promotes Proliferation and Inhibits Apoptosis of Gastric Cancer Cells via Upregulating TCF7 mRNA Translation.
FTO demethylates regulates cell-cycle progression by controlling CCND1 expression in luteinizing goat granulosa cells.
Lentinan mitigates pemetrexed chemoresistance by the PI3K/Akt pathway in non-small cell lung cancer.
p16 and p53 can Serve as Prognostic Markers for Head and Neck Squamous Cell Carcinoma.
Anti-pancreatic cancer activity of cassane diterpenoids isolated from the seeds of Caesalpinia sappan mediated by autophagy activation via ROS/AMPK/mTORC1 pathway.
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway.
HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis.
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Hydrogel loaded with thiolated chitosan modified taxifolin liposome promotes osteoblast proliferation and regulates Wnt signaling pathway to repair rat skull defects.
A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC.
FOLR1-stabilized β-catenin promotes laryngeal carcinoma progression through EGFR/AKT/GSK-3β pathway.
Metformin: A promising clinical therapeutical approach for BPH treatment via inhibiting dysregulated steroid hormones-induced prostatic epithelial cells proliferation.
Transcriptomics and molecular docking reveal the potential mechanism of lycorine against pancreatic cancer.
IGF2BP2 Drives Cell Cycle Progression in Triple-Negative Breast Cancer by Recruiting EIF4A1 to Promote the m6A-Modified CDK6 Translation Initiation Process.
Unlocking the role of EIF5A: A potential diagnostic marker regulating the cell cycle and showing negative correlation with immune infiltration in lung adenocarcinoma.
MiR-199a-5p inhibits dermal papilla cells proliferation by regulating VEGFA expression in cashmere goat.
Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer.
A transcriptome based molecular classification scheme for cholangiocarcinoma and subtype-derived prognostic biomarker.
Silencing geranylgeranyltransferase I inhibits the migration and invasion of salivary adenoid cystic carcinoma through RhoA/ROCK1/MLC signaling and suppresses proliferation through cell cycle regulation.
Elafibranor emerged as a potential chemotherapeutic drug for non-muscle invasive bladder cancer.
Decreased PDLIM1 expression in endothelial cells contributes to the development of intracranial aneurysm.
Aurora kinase B disruption suppresses pathological retinal angiogenesis by affecting cell cycle progression.
Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation.
Prognosis and biological function of SGOL1 in clear cell renal cell carcinoma: a multiomics analysis.
Effects of sulforaphane on prostate cancer stem cells-like properties: In vitro and molecular docking studies.
Circ-RNF111 Promotes Proliferation of Ovarian Cancer Cell SKOV-3 by Targeting the MiR-556-5p/CCND1 Axis.
FOXG1 interaction with SATB2 promotes autophagy to alleviate neuroinflammation and mechanical abnormal pain in rats with lumbar disc herniation.
Revealing the mechanism of Gualou-Xiebai against myocardial ischemia based on network pharmacology and energy metabolism strategies.
Testosterone-Induced H3K27 Deacetylation Participates in Granulosa Cell Proliferation Suppression and Pathogenesis of Polycystic Ovary Syndrome.
Methyltransferase-Like 3-Driven N6-Methyladenosine Modification of Recombination Signal Binding Protein for Immunoglobulin Kappa J Region Promotes Vascular Remodeling in Pulmonary Hypertension.
MiR-135b-5p promotes cetuximab resistance in colorectal cancer by regulating FOXN3.
CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β-catenin signaling pathway.
Network pharmacology and anticancer mechanism study of Dendrobium nobile dendrobine in the treatment of colorectal cancer.
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
Upregulation of collagen type X alpha 1 promotes the progress of triple-negative breast cancer via Wnt/β-catenin signaling.
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells.
Long non-coding RNA NEAT1 induced by BHLHE40 activates Wnt/β-catenin signaling and potentiates colorectal cancer progression.
Bacillus subtilis alleviates excessive apoptosis of intestinal epithelial cells in intrauterine growth restriction suckling piglets via the members of Bcl-2 and caspase families.
N-desmethyldauricine from Menispermum dauricum DC suppresses triple-negative breast cancer growth in 2D and 3D models by downregulating the NF-κB signaling pathway.
Liensinine inhibits progression of intrahepatic cholangiocarcinoma by regulating TGF-β1 /P-smad3 signaling through HIF-1a.
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Eukaryotic initiation factor 3a promotes the development of diffuse large B-cell lymphoma through regulating cell proliferation.
Glutamine Promotes Porcine Intestinal Epithelial Cell Proliferation through the Wnt/β-Catenin Pathway.
CHOP regulated by METTL14-m6A affects cell cycle arrest and regorafenib sensitivity in HCC cells.
DCDC2 inhibits hepatic stellate cell activation and ameliorates CCl(4)-induced liver fibrosis by suppressing Wnt/β-catenin signaling.
METTL14 promotes neuroblastoma formation by inhibiting YWHAH via an m6A-YTHDF1-dependent mechanism.
B-Myb deficiency boosts bortezomib-induced immunogenic cell death in colorectal cancer.
LAMP5 may promote MM progression by activating p38.
Effects of Ginsenoside Rg1 on the Biological Behavior of Human Amnion-Derived Mesenchymal Stem/Stromal Cells (hAD-MSCs).
P16(INK4a) Regulates ROS-Related Autophagy and CDK4/6-Mediated Proliferation: A New Target of Myocardial Regeneration Therapy.
Comprehensive Analysis of Sideroflexin 4 in Hepatocellular Carcinoma by Bioinformatics and Experiments.
The Potent Novel CDK4/6 Inhibitor TQB3616 in Hormone Receptor Positive Breast Cancer: Preclinical Characterization with in vitro and Human Tumor Xenograft Models.
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
SHCBP1 Promotes the Proliferation of Breast Cancer Cells by Inhibiting CXCL2.
HECW2 promotes the progression and chemoresistance of colorectal cancer via AKT/mTOR signaling activation by mediating the ubiquitin-proteasome degradation of lamin B1.
Reduced FANCE Confers Genomic Instability and Malignant Behavior by Regulating Cell Cycle Progression in Endometrial Cancer.
Significance of NotchScore and JAG1 in predicting prognosis and immune response of low-grade glioma.
Adjuvant therapy with Huatan Sanjie Granules improves the prognosis of patients with primary liver cancer: a cohort study and the investigation of its mechanism of action based on network pharmacology.
Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study.
Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI.
PFDN2 promotes cell cycle progression via the hnRNPD-MYBL2 axis in gastric cancer.
A Novel Gene Pair CSTF2/DPE2A Impacts Prognosis and Cell Cycle of Hepatocellular Carcinoma.
Knockdown of NF-κB activating protein promotes pancreatic cancer growth and metastasis through mTOR signaling pathway.
Royal jelly acid suppresses hepatocellular carcinoma tumorigenicity by inhibiting H3 histone lactylation at H3K9la and H3K14la sites.
Large HBV Surface Protein-Induced Unfolded Protein Response Dynamically Regulates p27 Degradation in Hepatocellular Carcinoma Progression.
SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3β signaling pathway through P53.
Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression.
PAQR5 inhibits the growth and metastasis of clear cell renal cell carcinoma by suppressing the JAK/STAT3 signaling pathway.
Brexpiprazole suppresses cell proliferation and de novo lipogenesis through AMPK/SREBP1 pathway in colorectal cancer.
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
Aquaporin-7 Facilitates Proliferation and Adipogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Regulating Hydrogen Peroxide Transport.
Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via a nuclear receptor (Nur77)-mediated epigenetic regulation of glutaminase 1.
Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase I.
LGR4 promotes tumorigenesis by activating TGF-β1/Smad signaling pathway in multiple myeloma.
Mechanism of the HIF-1α/VEGF/VEGFR-2 pathway in the proliferation and apoptosis of human haemangioma endothelial cells.
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Network pharmacology integrated with experimental validation revealed potential molecular mechanisms of Camellia nitidissima C. W. Chi in the treatment of lung cancer.
Elucidating the pharmacological effects of Compound Kushen injection on MYC-P15-CCND1 signaling pathway in nasopharyngeal carcinoma - An in vitro study.
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.
Inhibition of autophagy can promote the apoptosis of bladder cancer cells induced by SC66 through the endoplasmic reticulum stress pathway.
3-Acetyldeoxynivalenol induces apoptosis, barrier dysfunction and endoplasmic reticulum stress by inhibiting mTORC1-dependent autophagy in porcine enterocytes.
Comprehensive analysis of HOXC8 associated with tumor microenvironment characteristics in colorectal cancer.
Diallyl trisulfide inhibits gastric cancer stem cell properties through ΔNp63/sonic hedgehog pathway.
Methylation of lncSHGL promotes adipocyte differentiation by regulating miR-149/Mospd3 axis.
NAP1L5 facilitates pancreatic ductal adenocarcinoma progression via TRIM29-mediated ubiquitination of PHLPP1.
A novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation.
INHBA gene silencing inhibits proliferation, migration, and invasion of osteosarcoma cells by repressing TGF-β signaling pathway activation.
HDAC1-Mediated lncRNA Stimulatory Factor of Follicular Development to Inhibit the Apoptosis of Granulosa Cells and Regulate Sexual Maturity through miR-202-3p-COX1 Axis.
Circular RNA ZBTB46 depletion alleviates the progression of Atherosclerosis by regulating the ubiquitination and degradation of hnRNPA2B1 via the AKT/mTOR pathway.
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Upregulated TC1 and downregulated Chibby were correlated with the aberrant β-catenin expression in laryngeal squamous cell carcinoma.
Angelicin inhibits cell growth and promotes apoptosis in oral squamous cell carcinoma by negatively regulating DUSP6/cMYC signaling pathway.
Exploring the effect and mechanism of Haizao Yuhu decoction containing three variants of glycyrrhiza on goiter using an integrated strategy of network pharmacology and RNA sequencing.
Circular RNA transcriptome across multiple tissues reveal skeletal muscle-specific circPSME4 regulating myogenesis.
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
YWHAB knockdown inhibits cell proliferation whilst promoting cell cycle arrest and apoptosis in colon cancer cells through PIK3R2.
Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42.
Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition.
Knockdown of FGFR3 inhibits the proliferation, migration and invasion of intrahepatic cholangiocarcinoma.
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
The effects of the prognostic biomarker SAAL1 on cancer growth and its association with the immune microenvironment in lung adenocarcinoma.
Vacuolar protein sorting 35 (VPS35) acts as a tumor promoter via facilitating cell cycle progression in pancreatic ductal adenocarcinoma.
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress.
The location of estrogen receptor variant ER-α36 is associated with the invasion of glioblastoma.
A study of the role of multiple layer-by-layer assembled bionic extracellular matrix in promoting wound healing via activation of the Wnt signaling pathway.
MTAP-ANRIL gene fusion promotes melanoma epithelial-mesenchymal transition-like process by activating the JNK and p38 signaling pathways.
Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma.
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
NVS-ZP7-4 inhibits hepatocellular carcinoma tumorigenesis and promotes apoptosis via PI3K/AKT signaling.
Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription.
NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.
Biochemical and clinical effects of RPS20 expression in renal clear cell carcinoma.
MicroRNA-1205 Suppresses Hepatocellular Carcinoma Cell Proliferation via a CSNK2B/CDK4 Axis.
USP39 stabilizes β-catenin by deubiquitination and suppressing E3 ligase TRIM26 pre-mRNA maturation to promote HCC progression.
DNMT1-mediated lncRNA IFFD controls the follicular development via targeting GLI1 by sponging miR-370.
Exploration the role of INHBA in Hu sheep granulosa cells using RNA-Seq.
Astaxanthin Promotes the Survival of Adipose-Derived Stem Cells by Alleviating Oxidative Stress via Activating the Nrf2 Signaling Pathway.
Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK.
AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway.
Chidamide Induces Epstein-Barr Virus (EBV) Lytic Infection and Acts Synergistically with Tenofovir to Eliminate EBV-Positive Burkitt Lymphoma.
GTF2E2 downregulated by miR-340-5p inhibits the malignant progression of glioblastoma.
Glucose-responsive, antioxidative HA-PBA-FA/EN106 hydrogel enhanced diabetic wound healing through modulation of FEM1b-FNIP1 axis and promoting angiogenesis.
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
CircRNA0007766 accelerates cancer progression via miR-34c-5p/cyclin D1 axis in adenocarcinoma of the esophagogastric junction (AEG).
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Lnc-PKNOX1-1 inhibits tumor progression in cutaneous malignant melanoma by regulating NF-κB/IL-8 axis.
Fucoxanthin diminishes oxidative stress damage in human placenta-derived mesenchymal stem cells through the PI3K/Akt/Nrf-2 pathway.
GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase.
Molecular mechanism and therapeutic potential of HDAC9 in intervertebral disc degeneration.
Artesunate and cisplatin synergistically inhibit HNSCC cell growth and promote apoptosis with artesunate‑induced decreases in Rb and phosphorylated Rb levels.
The MAD2B-APC/C-MDM2 axis mediates acute kidney injury by modulating p53.
miR-101-5p overexpression suppresses the proliferation of goat spermatogonial stem cells by targeting EZH2.
221S-1a inhibits endothelial proliferation in pathological angiogenesis through ERK/c-Myc signaling.
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
HHEX suppresses advanced thyroid cancer by interacting with TLE3.
WITHDRAWN: Expression of Tmem41b and MMP13 associated with poor outcome in osteosarcomas.
MFAP2 promotes the progression of oral squamous cell carcinoma by activating the Wnt/β-catenin signaling pathway through autophagy.
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Inhibition of hyaluronic acid degradation pathway suppresses glioma progression by inducing apoptosis and cell cycle arrest.
NUCKS1 promotes the progression of colorectal cancer via activating PI3K/AKT/mTOR signaling pathway.
Atractylenolide III suppresses senescence-associated secretome via inhibiting cGAS/NF-κB pathway in hepatic stellate cells.
CircHGS enhances the progression of bladder cancer by regulating the miR-513a-5p/VEGFC axis and activating the AKT/mTOR signaling pathway.
Exosome miR-3184-5p inhibits gastric cancer growth by targeting XBP1 to regulate the AKT, STAT3, and IRE1 signalling pathways.
Therapeutic efficacy of a MMAE-based anti-DR5 drug conjugate Oba01 in preclinical models of pancreatic cancer.
[HSDL2 overexpression promotes rectal cancer progression by regulating cancer cell cycle and promoting cell proliferation].
Berberine promotes IGF2BP3 ubiquitination by TRIM21 to induce G1/S phase arrest in colorectal cancer cells.
Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells.
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
Aldolase A promotes cell proliferation and cisplatin resistance via the EGFR pathway in gastric cancer.
CSTF2 Acts as a Prognostic Marker Correlated with Immune Infiltration in Hepatocellular Carcinoma.
Analysis of regulating activities of 5'-epiequisetin on proliferation, apoptosis, and migration of prostate cancer cells in vitro and in vivo.
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.
The SKA3-DUSP2 Axis Promotes Gastric Cancer Tumorigenesis and Epithelial-Mesenchymal Transition by Activating the MAPK/ERK Pathway.
A novel HCC prognosis predictor PDSS1 affects the cell cycle through the STAT3 signaling pathway in HCC.
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
Omentin-1 promoted proliferation and ameliorated inflammation, apoptosis, and degeneration in human nucleus pulposus cells.
Inhibition of cannabinoid receptor type 1 sensitizes triple-negative breast cancer cells to ferroptosis via regulating fatty acid metabolism.
High expression of eIF4A1 predicts unfavorable prognosis in clear cell renal cell carcinoma.
Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies.
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway.
L-arginine stimulates the proliferation of mouse mammary epithelial cells and the development of mammary gland in pubertal mice by activating the GPRC6A/PI3K/AKT/mTOR signalling pathway.
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway.
Integrative and Comprehensive Pan-Cancer Analysis of Lymphocyte-Specific Protein Tyrosine Kinase in Human Tumors.
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.
G protein subunit gamma 5 promotes the proliferation, metastasis and glycolysis of breast cancer cells through the Wnt/β-catenin pathway.
MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.
FL118, acting as a 'molecular glue degrader', binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c-Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy.
MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion.
Taraxasterol prompted the anti-tumor effect in mice burden hepatocellular carcinoma by regulating T lymphocytes.
NCAPH regulates gastric cancer progression through DNA damage response.
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury.
Cucurbitacin E Triggers Cellular Senescence in Colon Cancer Cells via Regulating the miR-371b-5p/TFAP4 Signaling Pathway.
Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways.
Multifunctional photodynamic/photothermal nano-agents for the treatment of oral leukoplakia.
The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.
Depletion of B7-H4 from C3H10 T1/2 Mesenchymal Stem Cells Attenuates their Immunomodulatory Therapy in Experimental Autoimmune Encephalomyelitis Mice.
Suppression of the Inhibitory Effect of circ_0036176-Translated Myo9a-208 on Cardiac Fibroblast Proliferation by miR-218-5p.
Damnacanthal isolated from morinda species inhibited ovarian cancer cell proliferation and migration through activating autophagy.
N-methyl-D-aspartate receptor blockers attenuate bleomycin-induced pulmonary fibrosis by inhibiting endogenous mesenchymal stem cells senescence.
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.
Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress.
Role of lncRNA LINC01194 in hepatocellular carcinoma via the miR-655-3p/SMAD family member 5 axis.
Interplay between liver circadian rhythm and regeneration after PHx.
ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.
Anlotinib combined with temozolomide suppresses glioblastoma growth via mediation of JAK2/STAT3 signaling pathway.
l-Argine regulates the proliferation, apoptosis and endocrine activity by alleviating oxidative stress in sheep endometrial epithelial cells.
Polygonum cuspidatum inhibits the growth of osteosarcoma cells via impeding Akt/ERK/EGFR signaling pathways.
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment.
Ginsenoside Rh4 Suppressed Metastasis of Lung Adenocarcinoma via Inhibiting JAK2/STAT3 Signaling.
Blockade of Nuclear β-Catenin Signaling via Direct Targeting of RanBP3 with NU2058 Induces Cell Senescence to Suppress Colorectal Tumorigenesis.
HMGB1 induces radioresistance through PI3K/AKT/ATM pathway in esophageal squamous cell carcinoma.
Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma.
lncRNA NEAT1-let 7b-P21 axis mediates the proliferation of neural stem cells cultured in vitro promoted by radial extracorporeal shock wave.
Tumor-targeted dual-starvation therapy based on redox-responsive micelle nanosystem with co-loaded LND and BPTES.
Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis.
NORAD promotes multiple myeloma cell progression via BMP6/P-ERK1/2 axis.
Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats.
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis.
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
FANCD2 promotes the malignant behavior of endometrial cancer cells and its prognostic value.
Aerobic glycolysis and tumor progression of hepatocellular carcinoma are mediated by ubiquitin of P53 K48-linked regulated by TRIM37.
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Long noncoding RNA BMPR1B-AS1 facilitates endometrial cancer cell proliferation and metastasis by sponging miR-7-2-3p to modulate the DCLK1/Akt/NF-κB pathway.
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
Alpha-linolenic acid inhibits hepatocellular carcinoma cell growth through Farnesoid X receptor/β-catenin signaling pathway.
High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis.
FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.
MiR-125b enhances doxorubicin-induced cardiotoxicity by suppressing the nucleus-cytoplasmic translocation of YAP via targeting STARD13.
Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.
Histone methyltransferase KMT2D cooperates with MEF2A to promote the stem-like properties of oral squamous cell carcinoma.
Lactation Activity and Mechanism of Milk-Protein Synthesis by Peptides from Oyster Hydrolysates.
Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling.
MicroRNA-146a promotes proliferation, migration, and invasion of HepG2 via regulating FLAP.
Identification and Validation of HOTAIRM1 as a Novel Biomarker for Oral Squamous Cell Carcinoma.
Transmembrane Protein Ttyh1 Maintains the Quiescence of Neural Stem Cells Through Ca(2+)/NFATc3 Signaling.
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
Sinomenine Suppresses Development of Hepatocellular Carcinoma Cells via Inhibiting MARCH1 and AMPK/STAT3 Signaling Pathway.
Acyl-CoA Thioesterase 7 is Transcriptionally Activated by Krüppel-Like Factor 13 and Promotes the Progression of Hepatocellular Carcinoma.
Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.
In Hepatocellular Carcinoma, miRNA-296-3p Targets MSL2 and Suppresses Cell Proliferation and Invasion.
MRC2 Promotes Proliferation and Inhibits Apoptosis of Diabetic Nephropathy.
Effects of MicroRNA-195-5p on Biological Behaviors and Radiosensitivity of Lung Adenocarcinoma Cells via Targeting HOXA10.
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Downregulation of m(6)A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.
Loss of DAB2IP Contributes to Cell Proliferation and Cisplatin Resistance in Gastric Cancer.
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
ACTL6A Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells and Correlates with Poor Clinical Outcomes.
Network pharmacology-guided mechanism study uncovers inhibitory effect of Mahuang Decoction on lung cancer growth by impeding Akt/ERK signaling pathways.
Coronin 6 promotes hepatocellular carcinoma progression by enhancing canonical Wnt/beta-catenin signaling pathway.
ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2.
Kaempferol Ameliorates the Inhibitory Activity of Dexamethasone in the Osteogenesis of MC3T3-E1 Cells by JNK and p38-MAPK Pathways.
Exploring the Prognostic Value, Immune Implication and Biological Function of H2AFY Gene in Hepatocellular Carcinoma.
Myricetin Induces Autophagy and Cell Cycle Arrest of HCC by Inhibiting MARCH1-Regulated Stat3 and p38 MAPK Signaling Pathways.
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Periplocymarin Induced Colorectal Cancer Cells Apoptosis Via Impairing PI3K/AKT Pathway.
CDCA7 Facilitates Tumor Progression by Directly Regulating CCNA2 Expression in Esophageal Squamous Cell Carcinoma.
Oleic Acid and Insulin as Key Characteristics of T2D Promote Colorectal Cancer Deterioration in Xenograft Mice Revealed by Functional Metabolomics.
Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
The lncRNA ADAMTS9-AS2 Regulates RPL22 to Modulate TNBC Progression via Controlling the TGF-β Signaling Pathway.
Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway.
miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.
Paired-like homeodomain transcription factor 2 affects endometrial cell function and embryo implantation through the Wnt/β-catenin pathway.
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.
PHLDA3 exerts an antitumor function in prostate cancer by down-regulating Wnt/β-catenin pathway via inhibition of Akt.
ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway.
Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-AKT signaling pathway as revealed by network pharmacology and in vitro experimental verification.
Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities.
TMEM98, a novel secretory protein, promotes endothelial cell adhesion as well as vascular smooth muscle cell proliferation and migration.
MiR-3663-3p Inhibits the Progression of Gastric Cancer Through the CCND1 Pathway.
Apatinib regulates the growth of gastric cancer cells by modulating apoptosis and autophagy.
Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.
LINC00857 contributes to proliferation and lymphomagenesis by regulating miR-370-3p/CBX3 axis in diffuse large B-cell lymphoma.
eIF6 promotes the malignant progression of human hepatocellular carcinoma via the mTOR signaling pathway.
LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.
Role of Glycated High Mobility Group Box-1 in Gastric Cancer.
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.
Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway.
Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells.
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
DNA methylation mediated RSPO2 to promote follicular development in mammals.
Epidermal stem cells maintain stemness via a biomimetic micro/nanofiber scaffold that promotes wound healing by activating the Notch signaling pathway.
Puromycin-sensitive aminopeptidase is required for C2C12 myoblast proliferation and differentiation.
Tacrolimus inhibits oral carcinogenesis through cell cycle control.
Methylation of NRN1 is a novel synthetic lethal marker of PI3K-Akt-mTOR and ATR inhibitors in esophageal cancer.
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V) 1.5-mediated EMT and FAK/Paxillin signaling pathway.
Long Non-Coding RNA LOC648987 Promotes Proliferation and Metastasis of Renal Cell Carcinoma by Regulating Epithelial-Mesenchymal Transition.
ActivinA activates Notch1-Shh signaling to regulate proliferation in C2C12 skeletal muscle cells.
Ezrin Promotes the Proliferation, Migration, and Invasion of Ovarian Cancer Cells.
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L-formate axis.
MicroRNA-4423-3p inhibits proliferation of fibroblast-like synoviocytes by targeting matrix metalloproteinase 13 in rheumatoid arthritis.
MiR-130a-3p suppresses colorectal cancer growth by targeting Wnt Family Member 1 (WNT1).
α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway.
Roles of WNT6 in Sheep Endometrial Epithelial Cell Cycle Progression and Uterine Glands Organogenesis.
CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.
LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma.
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Dimethyl fumarate inhibits antibody-induced platelet destruction in immune thrombocytopenia mouse.
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
ESM1 promotes triple-negative breast cancer cell proliferation through activating AKT/NF-κB/Cyclin D1 pathway.
M2 Macrophage-Derived Exosomal miR-590-3p Attenuates DSS-Induced Mucosal Damage and Promotes Epithelial Repair via the LATS1/YAP/ β-Catenin Signalling Axis.
Circular RNA circ_0005774 contributes to proliferation and suppresses apoptosis of acute myeloid leukemia cells via circ_0005774/miR-192-5p/ULK1 ceRNA pathway.
Ixazomib inhibits myeloma cell proliferation by targeting UBE2K.
F4/80(+) Kupffer Cell-Derived Oncostatin M Sustains the Progression Phase of Liver Regeneration through Inhibition of TGF-β2 Pathway.
Helium/Argon-Generated Cold Atmospheric Plasma Facilitates Cutaneous Wound Healing.
Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer.
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Integrated Bioinformatics Analysis of the Clinical Value and Biological Function of ATAD2 in Hepatocellular Carcinoma.
UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.
Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells.
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
miR-454 suppresses the proliferation and invasion of ovarian cancer by targeting E2F6.
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration.
GRHL2 Upregulation Predicts a Poor Prognosis and Promotes the Resistance of Serous Ovarian Cancer to Cisplatin.
A Novel lncRNA ENST00000512916 Facilitates Cell Proliferation, Migration and Cell Cycle Progression in Ameloblastoma.
NCAPG Induces Cell Proliferation in Cardia Adenocarcinoma via PI3K/AKT Signaling Pathway.
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.
CDC27 Promotes Tumor Progression and Affects PD-L1 Expression in T-Cell Lymphoblastic Lymphoma.
Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression.
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer.
Let-7b downgrades CCND1 to repress osteogenic proliferation and differentiation of MC3T3-E1 cells: An implication in osteoporosis.
Fatty acid synthase contributes to epithelial-mesenchymal transition and invasion of salivary adenoid cystic carcinoma through PRRX1/Wnt/β-catenin pathway.
CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer.
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Anthocyanins from Aronia melanocarpa Induce Apoptosis in Caco-2 Cells through Wnt/β-Catenin Signaling Pathway.
LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest.
Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota.
Cell adhesion molecule 4 suppresses cell growth and metastasis by inhibiting the Akt signaling pathway in non-small cell lung cancer.
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway.
Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer.
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression.
HOTAIR-EZH2 inhibitor AC1Q3QWB upregulates CWF19L1 and enhances cell cycle inhibition of CDK4/6 inhibitor palbociclib in glioma.
Knockdown of Rab9 Suppresses the Progression of Gastric Cancer Through Regulation of Akt Signaling Pathway.
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Neutrophil extracellular traps mediate the crosstalk between glioma progression and the tumor microenvironment via the HMGB1/RAGE/IL-8 axis.
ERO1L promotes NSCLC development by modulating cell cycle-related molecules.
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
lncRNA RP11-624L4.1 Is Associated with Unfavorable Prognosis and Promotes Proliferation via the CDK4/6-Cyclin D1-Rb-E2F1 Pathway in NPC.
siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation.
Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells.
Magnetic targeting enhances the cutaneous wound healing effects of human mesenchymal stem cell-derived iron oxide exosomes.
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
METTL3/YTHDF2 m(6) A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
Mechanism of inhibiting proliferation of hepatocellular carcinoma Hepa1-6 cells by embryonic stem cell-conditioned medium.
Effect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways.
Loss of hnRNPA2B1 inhibits malignant capability and promotes apoptosis via down-regulating Lin28B expression in ovarian cancer.
UHRF1 Promotes Proliferation of Human Adipose-Derived Stem Cells and Suppresses Adipogenesis via Inhibiting Peroxisome Proliferator-Activated Receptor γ.
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer.
Oxymatrine Inhibits the Proliferation and Invasion of Breast Cancer Cells via the PI3K Pathway.
miR-671-5p Inhibits Tumor Proliferation by Blocking Cell Cycle in Osteosarcoma.
REG4 is an indicator for KRAS mutant lung adenocarcinoma with TTF-1 low expression.
Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway.
Upregulation of ERp57 promotes clear cell renal cell carcinoma progression by initiating a STAT3/ILF3 feedback loop.
Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism.
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.
Forkhead Box R2 Knockdown Decreases Chemoresistance to Cisplatin via MYC Pathway in Bladder Cancer.
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Upregulation of lncRNA DGCR5 correlates with better prognosis and inhibits bladder cancer progression via transcriptionally facilitating P21 expression.
PLAGL2 and POFUT1 are regulated by an evolutionarily conserved bidirectional promoter and are collaboratively involved in colorectal cancer by maintaining stemness.
Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer.
[MiR-222-3р Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2].
MiR-26b suppresses hepatocellular carcinoma development by negatively regulating ZNRD1 and Wnt/β-catenin signaling.
Glycogen phosphorylase B promotes ovarian cancer progression via Wnt/β-catenin signaling and is regulated by miR-133a-3p.
Phenotypic transition of tumor cells between epithelial- and mesenchymal-like state during adaptation to acidosis.
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
miR-10b promoted melanoma progression through Wnt/β-catenin pathway by repressing ITCH expression.
lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.
Role of Daucosterol Linoleate on Breast Cancer: Studies on Apoptosis and Metastasis.
Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.
The natural agent rhein induces β-catenin degradation and tumour growth arrest.
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.
Modulation of cyclins and p53 in mesangial cell proliferation and apoptosis during Habu nephritis.
FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
GOLPH3 is a potential therapeutic target and a prognostic indicator of poor survival in bladder cancer treated by cystectomy.
Zhang X, Fu Y, Du Y, Xiong W, Wang J, Zhang H, Luo Y, Zhao Y, Shang P
American journal of cancer research 2026;16(1):51-69
American journal of cancer research 2026;16(1):51-69
Asiatic Acid Ameliorates MNNG-Induced Chronic Atrophic Gastritis by Inhibiting the Activation of the HRAS/PI3K/AKT/GSK3β Signaling Axis.
Zhou F, Zhu C, Yuan W, Peng W, Xu Q, Yang H, Cao R, Wang B, Wang M, Xu H
Phytotherapy research : PTR 2026 May;40(5):2210-2229
Phytotherapy research : PTR 2026 May;40(5):2210-2229
Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression.
Deng C, Cai S, Guo C, Khan S, Liu L, Tian Q, Ma Z, Zhang J, Zhao L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e20917
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(26):e20917
TRIM35 inhibits endometrial cancer progression via ubiquitination and degradation of EIF3E.
Wang Q, Ning N, Li Y
Cellular signalling 2026 Mar;139:112339
Cellular signalling 2026 Mar;139:112339
Plasma-activated hydrogel promotes postoperative colonic anastomotic leak healing.
Deng X, Ren K, Min T, Ma Y, Peng Y, Wang S, Zhang B, Xie X, Nan Y, Tong S, Liu Y, Zhang Y, Li K, Wang W, Hao N, Zhang G, Dang C, Sun T, Zhu K, Zhang H
Journal of advanced research 2026 Mar 6;
Journal of advanced research 2026 Mar 6;
TFAP2A regulates SGPP2 transcription to promote lipid accumulation and activate the Wnt/β-catenin signaling pathway to promote malignant progression in lung adenocarcinoma.
Li Q, Li J, Zhang C, Deng Y, Yang B, Ma L, Liu Y, Wang C, Xu L, Mei J
Journal of translational medicine 2026 Mar 4;24(1)
Journal of translational medicine 2026 Mar 4;24(1)
Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation.
Lin TS, Wan J, He J, Cui S, Huang Y, Zhang B, Huang HY, Zhu K, Chen J, Zhang T, Li S, Hu L, Wang Y, Huang HD, Tang P, Lin YC
Pharmaceutics 2026 Mar 3;18(3)
Pharmaceutics 2026 Mar 3;18(3)
A new candidate tumor suppressor tRF-Ser inhibits gastric cancer progression by regulating the CNBP/HSPA8 axis.
Jiao J, Wang G, Liu J, Xiao K, Gao Z, Dong D, Shan K, Cui H, Shang L, Li L, Zhang C
Cell death & disease 2026 Mar 25;17(1)
Cell death & disease 2026 Mar 25;17(1)
CCT3-mediated regulation of XPO1/RB1 axis stability promotes cellular senescence and tumor progression in clear cell renal carcinoma.
Cao Y, Xu C, Liu Y, Shi B, Li X, Li J, Zhang B, Zhang Z, Dai S, Sun Q, Gu J
iScience 2026 Mar 20;29(3):114840
iScience 2026 Mar 20;29(3):114840
The role of FPR3 in remodeling the immune microenvironment and lung metastasis of colon adenocarcinoma.
Xu N, Xia T, Wu M, Ye F, Zhao W, Zhao M, Mao Y, Ge Y, Du J
Cellular signalling 2026 Jun;142:112420
Cellular signalling 2026 Jun;142:112420
A multimodal ROS logic-gated therapeutic platform disrupts the vicious cycle of senescence to promote aged bone defect repair.
Sun X, Xie S, Fang Y, Zhang D, Wang W, Sun Z, Lu J, Yue X, Kong W, Fu D, Xu X, Dai K, Wang J, Wei J, Sun X
Bioactive materials 2026 Jul;61:692-711
Bioactive materials 2026 Jul;61:692-711
Design, synthesis and anti-bladder cancer activity of novel dihydroartemisinin-ibuprofen hybrids.
Yu H, Liu D, Xu J, Li A, Yan X, Bejoma T, Li Y, Yang J, Peng P, Zhao Q
Bioorganic chemistry 2026 Jul 15;176:109893
Bioorganic chemistry 2026 Jul 15;176:109893
Pyrimethamine regulates m6A modification of CCND1 via METTL14/YTHDF2 to inhibit hepatocellular carcinoma.
Han X, Wang K, Liu C, Yin S, Shao Y, Zhang J, Wang D, Pan G, Yu H
Bioorganic chemistry 2026 Jul 15;176:109892
Bioorganic chemistry 2026 Jul 15;176:109892
QiShenYiQi dripping pills ameliorate post-myocardial infarction cardiac fibrosis via modulation of the cAMP/Rap1 and PI3K/Akt signaling pathways.
Liu Z, Chen S, Fu H, Li K, Liu H, Qin L, Wang L, Jin J, Yin L, Chen J
Fitoterapia 2026 Jan;188:107020
Fitoterapia 2026 Jan;188:107020
SIGLEC15 modulates the immunosuppressive microenvironment and suppresses malignant phenotypes in triple-negative breast cancer.
Tan Z, Xin H, Chen J, Lei M, Tu G, Tang L
Genes & diseases 2026 Jan;13(1):101799
Genes & diseases 2026 Jan;13(1):101799
Time-resolved multiomics profiling reveals chromatin O-GlcNAc modification promotes senescence-associated transcriptional program.
Zhang N, Zhao R, Zhong X, Dong Q, Liu Y, Yu K, Han L, Meng F, Wu J, Chen Q, Li X, Chen Q, Zhang K, Huang H, Zhang J, Wu S, Ren Y, Wang W, Liu Y
Nature communications 2026 Jan 8;17(1):1406
Nature communications 2026 Jan 8;17(1):1406
Cyclin D1/D2-CDK4 Drives Cell Migration by Orchestrating Cytoskeletal Dynamics Through a TGFβ-FAK-Rac1 Axis.
Guo R, Wang Y, Zhang A, Jirawatnotai S, Chu C, Liu L
International journal of molecular sciences 2026 Jan 26;27(3)
International journal of molecular sciences 2026 Jan 26;27(3)
Inhibition of the RORC/GPX4 mediated ferroptosis regulatory axis suppresses tumor growth and alleviates enzalutamide resistance in prostate cancer.
Li Y, Zhang B, Zhang Z, Yan W, Wang H, Xu X, Lv A, Liao Z, Guo L
Cellular & molecular biology letters 2026 Jan 24;31(1):11
Cellular & molecular biology letters 2026 Jan 24;31(1):11
The prognostic value of miR-323b-5p in non-small cell lung cancer and its mechanism of targeting IL1A in regulating the proliferation and cell cycle of non-small cell lung cancer cells.
Wu Y, Duan Z, Yan D, Yue J, Liu C
Discover oncology 2026 Jan 23;17(1):314
Discover oncology 2026 Jan 23;17(1):314
TRV130 inhibits colon cancer progression via suppressing the Hedgehog signaling pathway: in vitro and in vivo evidence.
Zhuang Y, Jiang C, Guo Y, Sun J
Hereditas 2026 Jan 19;163(1):26
Hereditas 2026 Jan 19;163(1):26
Mechanisms underlying the therapeutic effects of Amygdalin in treating Cervical Cancer based on multi-omics analysis.
Jiang Q, Xu R, Cheng J, Shi Y, Zhu T, Yu M, Cui X, Lin C
Journal of pharmaceutical and biomedical analysis 2026 Jan 15;268:117232
Journal of pharmaceutical and biomedical analysis 2026 Jan 15;268:117232
Decoding the healing secrets of Gegenqinlian decoction: A promising approach to radiation-induced intestinal injury.
Zhang M, Wang SJ, Du XQ, Li GA, Yu YY, Zhang YQ, Liu WJ, Song F, Cao W, Sun Y, Li XQ
Journal of ethnopharmacology 2026 Jan 10;354:120473
Journal of ethnopharmacology 2026 Jan 10;354:120473
Genome-wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer.
Wang X, Mi B, Lv J, Tang X, Huang J, Liu F, Xing Y, Wen X, Wang Y, Zhong Y
Oncology letters 2026 Feb;31(2):62
Oncology letters 2026 Feb;31(2):62
SREBP1 knockdown triggers ferroptosis by suppressing the Nrf2-XCT/GPX4 axis in ovarian cancer.
Nie R, Zhou H, Chen L, Quan H, Zhang Y, Lin Z
Cell death discovery 2026 Feb 18;12(1)
Cell death discovery 2026 Feb 18;12(1)
m6A methylation-modified ETV1 drives multiple myeloma progression and M2 polarization of tumor-associated macrophage through transcriptional activation of RBMS1.
Liu Y, Geng Y, Zheng B, Zhang A, Yang K, Mao Y, Jiang L
Journal of translational medicine 2026 Feb 13;24(1)
Journal of translational medicine 2026 Feb 13;24(1)
DNA Methylation-Regulated FAM107A Affects Colorectal Carcinogenesis by Inhibiting FOXM1.
Liu Y, Sun J, Shi Y, Wang L, Zhang X, Chen L
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2026 Dec;39(1):2633933
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2026 Dec;39(1):2633933
Genetic and pharmaceutical manipulation of H3K9 methyltransferase Suv39h1 promotes liver regeneration by unleashing HMGB2 transcription.
Lu Y, Zhou J, Miao X, Zeng S, Qin L, Xu Y, Wang S, Li Z
Experimental & molecular medicine 2026 Apr;58(4):1158-1171
Experimental & molecular medicine 2026 Apr;58(4):1158-1171
Gut microbial metabolite, sphingosine-1-phosphate (S1P), drives mesangial cell phenotypic transformation and accelerates progression of IgA nephropathy via CCL2-MET-FAK pathway.
Tang YY, Zhang DL, Huang LS, Hu P, Liu P, Wu JJ, Xie T, Sun WQ, Xu XD, Jin MP, He HD
Current research in microbial sciences 2025;9:100494
Current research in microbial sciences 2025;9:100494
LTF regulates glioblastoma progression and temozolomide resistance via the NF-κB signaling pathway.
Gao L, Xiao H, Lu H, Ma J, Zhu H
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e13821
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e13821
TIMM8A-TIMM13 Complex Exerts Oncogenic Functions in Lung Cancer.
Li S, Shi K, Wang Y, Zhang Y
Oncology research 2025;33(9):2435-2449
Oncology research 2025;33(9):2435-2449
Exosome-Delivered circFOXP1 Upregulates Autophagy and Promotes Hepatocellular Carcinoma Progression Through Its Encoded p196 Protein Targeting the KHDRBS3/ULK1 Axis.
Zhao P, Yin C, Liu R, Shao S, Ke W, Song Z
International journal of nanomedicine 2025;20:5247-5265
International journal of nanomedicine 2025;20:5247-5265
Overexpression of MCM3 as a prognostic biomarker correlated with cell proliferation, cell cycle and immune regulation in hepatocellular carcinoma.
Ju L, Wang H, Luo Y, Wang Y, Chen L, Han X, Lu R
Journal of Cancer 2025;16(5):1538-1554
Journal of Cancer 2025;16(5):1538-1554
NCAPG promotes the malignant progression of endometrioid cancer through LEF1/SEMA7A/PI3K-AKT.
Ren Z, Li X, Fu C
Journal of Cancer 2025;16(2):445-459
Journal of Cancer 2025;16(2):445-459
PSMD12 promotes hepatocellular carcinoma progression by stabilizing CDK1.
Peng X, Liu Z, Luo C, Sun R, Zhang Y, Li B, Zou Y, Zhu J, Yuan R
Frontiers in immunology 2025;16:1581398
Frontiers in immunology 2025;16:1581398
Gen-miR-5 derived from Gentianella acuta inhibits PFKP to prevent fibroblast activation and alleviate myocardial fibrosis.
Ge H, Du Z, Liu W, Wang L, Li J, Yang G, Li A
Frontiers in pharmacology 2025;16:1578877
Frontiers in pharmacology 2025;16:1578877
Triptolide alleviates psoriasis through inhibiting the Wnt5a/β-Catenin signaling pathway.
Chen E, Wang L, Wang Q, Cai Y, Dou Y, Qu H, Zhu J, Zhao H, Zheng S, Zhao C, Chen B
Frontiers in pharmacology 2025;16:1534118
Frontiers in pharmacology 2025;16:1534118
Exploration of the Mechanism of Action of Dendrobium officinale in the Treatment of Liver Cancer Based on Network Pharmacology, Molecular Docking and in vitro Validation.
Zhan S, Lu X, Guo H, Liu Y, Li Z, Xu W, Xia F, Tang H, Tian Y, Chen J, Lin X
Journal of hepatocellular carcinoma 2025;12:1973-1990
Journal of hepatocellular carcinoma 2025;12:1973-1990
Triflupromazine and tranylcypromine alleviate primary cisplatin resistance in lung adenocarcinoma by promoting LDHA-mediated AMBRA1 ubiquitination.
Wang Q, Zhang Y, Zhang Y, Zhai Y, Zhou X, Qin Y, Ding M, Tian Y, Zhang Z, Zhang P, Xu F
Biochemical pharmacology 2025 Sep;239:117073
Biochemical pharmacology 2025 Sep;239:117073
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
Huang QH, Tang XY, Huang QY, Zhi SB, Zheng XQ, Gan CY, Huang MF, Pan ZF, Zhong ZX
Biochemical pharmacology 2025 Sep;239:117014
Biochemical pharmacology 2025 Sep;239:117014
Mechanism of ferroptosis in hypoxia-induced pulmonary vascular remodeling in hypoxia pulmonary hypertension: a study based on the ACE2-Ang-(1-7)-Mas axis.
Abudukeremu A, Aikemu A, Yang T, Fang L, Shanahati D, Nijiati Y
Chemico-biological interactions 2025 Sep 5;418:111596
Chemico-biological interactions 2025 Sep 5;418:111596
CHD4 drives gastric cancer metastasis via MYH9/GSK3β/β-catenin axis and WNT/EMT pathway activation.
Shi Y, Zhao Z, Zhou S, Zhou Z, Huang Z, Zhou Z, Zhang C
Cancer letters 2025 Sep 28;628:217813
Cancer letters 2025 Sep 28;628:217813
NCAPH-YAP1 interaction promotes breast cancer stemness and tumor progression.
Qiu C, Wei Y, Li J
Stem cell research & therapy 2025 Sep 25;16(1):494
Stem cell research & therapy 2025 Sep 25;16(1):494
Exosomal miR-3529-3p increases the sensitivity of trastuzumab via Wnt/β-catenin signaling pathway by targeting HOOK3.
Zhu J, Lu Y, Zhang Q
International immunopharmacology 2025 Sep 23;162:115160
International immunopharmacology 2025 Sep 23;162:115160
Kuwanon A Targeted YWHAB in Hepatocellular Carcinoma Cells to Inhibit the Raf/MEK/ERK Signaling Pathway.
Xu J, Chang H, Wang Y, Du Y, Zhong L, Cui H
Cells 2025 Sep 23;14(19)
Cells 2025 Sep 23;14(19)
Transplanting neural stem cells overexpressing miRNA-21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28-let-7 signaling pathway.
Dai W, Li Y, Du J, Shen G, Fan M, Su Z, Xu F, Yuan F
Animal models and experimental medicine 2025 Oct;8(10):1760-1774
Animal models and experimental medicine 2025 Oct;8(10):1760-1774
Chidamide Accelerates the Death of Senescence-Like Diffuse Large B-Cell Lymphoma Cells With TP53 Mutation Induced by Doxorubicin.
Yin YY, Liu Y, Lu YQ, Tang ZM, Zhu ZX, Zhu MY, Chen HY, Hui H, Xu JY, Li H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71167
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71167
Canagliflozin inhibits hepatic stellate cells activation and proliferation by inhibiting PP2A-mediated β-catenin dephosphorylation to attenuate hepatic fibrosis.
Peng L, Zou Z, Zhou L, Li L, Lu W, Chen C, Xu Y, Liu Y, Lin J, Ye J
International immunopharmacology 2025 Oct 30;164:115347
International immunopharmacology 2025 Oct 30;164:115347
TRIM21 as a potential prognostic biomarker and therapeutic target affects the growth of pancreatic cancer.
Sun D, Zheng S, Wang S, Xue Y, Song S, Bai Y, Li X, Ci Y
Discover oncology 2025 Oct 30;16(1):1993
Discover oncology 2025 Oct 30;16(1):1993
CRL4(DCAF12) regulation of MCMBP ensures optimal licensing of DNA replication.
Yadav AK, Abdirov A, Ondruskova K, Negi S, Jamrichova K, Kolarova K, Dibus N, Krejci J, Polasek-Sedlackova H, Cermak L
Nature communications 2025 Oct 27;16(1):9391
Nature communications 2025 Oct 27;16(1):9391
Pan-cancer analysis of role of LOXL4 and experiment validation in osteosarcoma.
Chen W, Xie F, Lv J, Huang D, Zhong R, Wen Z, Sun J, Zheng S, Liu W, Zhong H, Huang S
Discover oncology 2025 Oct 21;16(1):1926
Discover oncology 2025 Oct 21;16(1):1926
RSL3 promotes PARP1 apoptotic functions by distinct mechanisms during ferroptosis.
Chen D, Xie F, Mo Y, Qin D, Zheng B, Chen L
Cellular & molecular biology letters 2025 Oct 2;30(1):109
Cellular & molecular biology letters 2025 Oct 2;30(1):109
Hexokinase HK2 regulates the MYH9-GSK3β/β-catenin axis to promote myocardial regeneration and repair after injury.
Zhang L, Zhang H, Ni J, Wu R, Feng Z, Wang Z, Qian L
European journal of pharmacology 2025 Oct 15;1005:178087
European journal of pharmacology 2025 Oct 15;1005:178087
miR-423-3p inhibits CTNNBIP1/WNT preventing hyperandrogenic polycystic ovary syndrome†.
Zhang S, Liu Y, Wang M, Ponikwicka-Tyszko D, Wolczynski S, Chen L, Huang X, Yao B, Rahman NA, Li X
Biology of reproduction 2025 Oct 14;113(4):856-869
Biology of reproduction 2025 Oct 14;113(4):856-869
Centromere protein I facilitates breast cancer tumorigenesis and disease progression through modulation of Wnt/β-Catenin signaling.
Wu C, Zhou Y, Mu Y, Cheng Y, Xu W, Huang M, Xu J, Li M, Gu J, Meng X, Qian D
Cancer cell international 2025 Oct 10;25(1):348
Cancer cell international 2025 Oct 10;25(1):348
FAM111B enhances glycolysis and promotes metastasis of prostate cancer by upregulating LDHA.
He Q, Li H, Cong Y, Chen K, Cheng L, Lv F, Zhang P, Ju Y, Yu Z, Chen J, Wang C, Song Y, Li X, Chen L, Xing Y
Neoplasia (New York, N.Y.) 2025 Nov;69:101227
Neoplasia (New York, N.Y.) 2025 Nov;69:101227
A synergy of CD133 overexpression and TGF-β supplementation in tumorigenesis of ovarian cancer cell lines in a three-dimensional sphere forming model.
Hung HC, Mao TL, Tsui KH, Fan MH, Minhalina AP, Liu CL
Cellular immunology 2025 Nov;417:105015
Cellular immunology 2025 Nov;417:105015
Polystyrene nanoplastics impair endometrial decidualization via cell cycle arrest and JNK-MAPK pathway-mediated oxidative stress in early pregnant mice.
Li JA, Wang LQ, Xu QJ, Wu XM, Pang XQ, He JX, Qiao QF, You HN, Wu YC, Zhou YJ
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115707
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115707
O-GlcNAcylation of PRDX1 enhances its stability and promotes liver cancer progression via activating LRP6-mediated Wnt signaling.
Dai L, Xu Z, Fan Y, Gao W, Yuan G, He S, Mao L
Cellular signalling 2025 Nov;135:112055
Cellular signalling 2025 Nov;135:112055
EBV-miR-BART5-3p promotes the proliferation of Burkitt lymphoma cells via glycolytic pathway.
Da D, Qi Y, Dang C, Xue L, Huang X, Wang X, Li H
Annals of hematology 2025 Nov;104(11):5731-5742
Annals of hematology 2025 Nov;104(11):5731-5742
MYST1-Mediated Lysine Acetylation Stabilizes KLF4 to Promote Intimal Hyperplasia.
Wang S, Liu Z, Wen J, Zhang C, Wu F, Zeng Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71247
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71247
Histone demethylase KDM9 activates the CCND1/AKT pathway to promote the malignant progression of gliomas through interaction with BRD2.
Cheng J, Peng X, Tang S, Zhou P, Zhou Z, Mao Z, Li D, Yang L, Peng J
Cellular and molecular life sciences : CMLS 2025 Nov 26;82(1):423
Cellular and molecular life sciences : CMLS 2025 Nov 26;82(1):423
tiRNA: An efficient and controllable gene silencing technology via translation inhibition.
Xia B, Cai J, He Z, Zhu Q
New biotechnology 2025 Nov 25;89:177-190
New biotechnology 2025 Nov 25;89:177-190
The local anesthetic, lidocaine, suppresses the growth of colon cancer SW480 cells by decreasing the voltage-gated sodium channel subunit Na(v)1.5.
Haraguchi-Suzuki K, Suzuki T, Nakasone C, Kawabata-Iwakawa R, Saito S
Scientific reports 2025 Nov 22;15(1):45018
Scientific reports 2025 Nov 22;15(1):45018
Radix Rehmanniae Praeparata Extract Enhances Liver Regeneration Through AMPK-Driven Metabolic Reprogramming.
Li C, Zheng Q, Li F, Zhang Y, Duan S, Liu J, Han Q, Liu R
Nutrients 2025 Nov 15;17(22)
Nutrients 2025 Nov 15;17(22)
Dual-Targeted Biomimetic Nanoparticles for Enhanced Delivery of Polyphyllin B Synergistically Induce Ferroptosis and Immunogenic Cell Death in Gastric Cancer.
Zu D, Yao J, Li X, Huang Y, Hu C, Deng M, Bao Q, Shi Y, Ye Z, Cheng X
ACS applied materials & interfaces 2025 Nov 12;17(45):61676-61694
ACS applied materials & interfaces 2025 Nov 12;17(45):61676-61694
Analysis of differential transcriptome expression reveals that ISG15 provides support for embryo development by promoting angiogenesis in porcine mesometrium.
Gan J, Wang Y, Zhang F, Zang X, Meng F, Gu T, Xu Z, Li Z, Cai G, Wu Z, Hong L
International journal of biological macromolecules 2025 May;306(Pt 4):141601
International journal of biological macromolecules 2025 May;306(Pt 4):141601
PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it.
Wu C, Gao Y, Jin Z, Huang Z, Wang H, Lu S, Guo S, Zhang F, Zhang J, Huang J, Tao X, Liu X, Zhang X, You L, Li Q, Wu J
Pharmacological research 2025 May;215:107743
Pharmacological research 2025 May;215:107743
AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep.
Xu H, Cai Y, Yang H, Zhang C, Liu W, Zhao B, Wang F, Zhang Y
Communications biology 2025 May 29;8(1):824
Communications biology 2025 May 29;8(1):824
Arjunolic acid inhibits Wnt3a-mediated macrophage M2 polarization to suppress osteosarcoma progression.
Li J, Zhang S, Yu C, Chen X, Zhong W, Shen Y
Genes & nutrition 2025 May 21;20(1):11
Genes & nutrition 2025 May 21;20(1):11
SERCA2 dysfunction accelerates angiotensin II-induced aortic aneurysm and atherosclerosis by induction of oxidative stress in aortic smooth muscle cells.
Wang L, Song J, Yang Z, Zhang H, Wang Y, Liu J, Wang S, Shi J, Tong X
Journal of molecular and cellular cardiology 2025 Mar;200:68-81
Journal of molecular and cellular cardiology 2025 Mar;200:68-81
CENPF (+) cancer cells promote malignant progression of early-stage TP53 mutant lung adenocarcinoma.
Xiong Y, Lei J, Wen M, Ma Y, Zhao J, Tian Y, Wan Z, Li X, Zhu J, Wang W, Ji X, Sun Y, Yang J, Zhang J, Xin S, Liu Y, Jia L, Han Y, Jiang T
Oncogenesis 2025 Mar 5;14(1):5
Oncogenesis 2025 Mar 5;14(1):5
NPC1L1 Drives Osteoporosis by Activating the C/EBPα/Cyp27a1/27-Hydroxycholesterol Axis: A Novel Therapeutic Target for Bone Loss.
Li B, Zhou W, Yu Y, Chen B, Lv Z, Zhang J, Zhang T, Sun S, Zhou L, Wang M
FASEB bioAdvances 2025 Jun;7(6):e70020
FASEB bioAdvances 2025 Jun;7(6):e70020
Deuterium-depleted water inhibits the malignant progression of colorectal cancer cells by modulating oxidative stress.
Li C, Cheng X, Jiang Y
Oncology reports 2025 Jun;53(6)
Oncology reports 2025 Jun;53(6)
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
He W, Wang X, Zhang J, Cao H, Ren S, Sun X, Yu H, Zhang G, Li C, Liu L, Wang C, He J
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β-Catenin Signaling Pathway.
Hao Y, Zhang X, Ran S, Li Y, Ye W, Wang S, Li X, Luo Z, Zhao J, Zong J, Zheng K, Li R, Zhang H, Lai L, Huang P, Zou Z, Zhan W, Yue Z, Wu J, Xia J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2413964
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2413964
Three-Dimensional Bioprinted Scaffolds Loaded with Multifunctional Magnesium-Based Metal-Organic Frameworks Improve the Senescence Microenvironment Prompting Aged Bone Defect Repair.
Sun X, Xu X, Zhao X, Ma J, Wang T, Yue X, Sun X, Li X, Sun X, Zhang W, Zhang K, Zhang D, Zhao X, Jin W, Wang J
ACS nano 2025 Jun 24;19(24):22141-22162
ACS nano 2025 Jun 24;19(24):22141-22162
Cytohesin-4/ARF6 facilitates the progression of acute myeloid leukemia through activating PIK3R5/PI3K/AKT pathway.
Qiu XF, He CM, Zeng YM, Deng XL, Liang GL, Zhong MX, Zou M, Xiong XJ, Zhang JD, Ye Y, Niu Q, Chen XL
iScience 2025 Jun 20;28(6):112634
iScience 2025 Jun 20;28(6):112634
Hepatic micropeptide modulates mitochondrial RNA processing machinery in hepatocellular carcinoma.
Zhu L, Liu F, Shi C, Su X, Tan M, Xie S, Yu M, Zou S, Tan Y, Xie S, Liu J, Yan Q, Neculai D, Sun Q, Liu W, Ding Y, Fu X, Shao J, Li X, Ding K, Yuan Y, Zhou T, Lin A
Molecular cell 2025 Jun 19;85(12):2303-2319.e7
Molecular cell 2025 Jun 19;85(12):2303-2319.e7
Mechanism of berbamine-mediated DNA damage in synovial fibroblasts to alleviate rheumatoid arthritis.
Huang Y, Gong K, Tao M, Zhu Y, Li Y, Wang Y, Wu H, Hao W, Sun X
European journal of pharmacology 2025 Jun 15;997:177597
European journal of pharmacology 2025 Jun 15;997:177597
KLF4 mediates the contradictory effects of phenylethyl isothiocyanate in gastric cancer intervention.
Zhang Q, Yang C, Zhou B, Gao X, Zhong C, Shi Y, Cao H, Zhu M
Medical oncology (Northwood, London, England) 2025 Jun 12;42(7):253
Medical oncology (Northwood, London, England) 2025 Jun 12;42(7):253
PELI2 inhibits colorectal cancer development through MAPK signaling pathway.
Liu J, Hu S, Zhao L, Yang Y, Wu G, Duan Y, Ma X, Wang P, Zhang Z, Zong H
Molecular medicine (Cambridge, Mass.) 2025 Jun 12;31(1):235
Molecular medicine (Cambridge, Mass.) 2025 Jun 12;31(1):235
YY1/HIF-1α/mROS positive-feedback loop exacerbates glomerular mesangial cell proliferation in mouse early diabetic kidney disease.
Yang TT, Shao YT, Cheng Q, He YT, Qiu Z, Pan DD, Zhang HM, Jiang ZZ, Yan M, Ying CJ, Li BJ, Liu JJ, Qian ST, Wang T, Yin XX, Lu Q
Acta pharmacologica Sinica 2025 Jul;46(7):1974-1989
Acta pharmacologica Sinica 2025 Jul;46(7):1974-1989
Phytochemical profile of bioactive Siraitia grosvenorii root fraction and its potential against nonsmall cell lung cancer in vitro and in vivo.
Wei Y, Jiang X, Song J, Yan X, Zhang J, Dong F, Li D, Liu H, Lu F
Fitoterapia 2025 Jul;184:106602
Fitoterapia 2025 Jul;184:106602
METTL3 regulates Ambra1 expression in an m6A-YTHDF2-dependent manner to promote mantle cell lymphoma progression.
Li S, Jiang Z, Wei W, Deng S, Duan T
Journal of translational medicine 2025 Jul 1;23(1):703
Journal of translational medicine 2025 Jul 1;23(1):703
Circular RNA circLIMK1-005 promotes the progression of lung adenocarcinoma by interacting with RPA1 protein to activate CDK4 signaling.
Yang X, Liu L, Yu Z, Chen Y, Xu S, Liu M, Wang M, Guo H, Zhang Z, Shan B, Cai S, Pan M, Zhang J, Wang F, Zheng Y
Cell death discovery 2025 Jul 1;11(1):297
Cell death discovery 2025 Jul 1;11(1):297
Lycorine hydrochloride interferes with energy metabolism to inhibit chemoresistant glioblastoma multiforme cell growth through suppressing PDK3.
Dong Q, Niu W, Mu M, Ye C, Wu P, Hu S, Niu C
Molecular and cellular biochemistry 2025 Jan;480(1):355-369
Molecular and cellular biochemistry 2025 Jan;480(1):355-369
Role of semaphorin7A in epithelial-mesenchymal transition and proliferative vitreoretinopathy.
Song S, Yang R, Su Y, Wang F
Experimental eye research 2025 Jan;250:110153
Experimental eye research 2025 Jan;250:110153
Taraxasterol regulates p53 transcriptional activity to inhibit pancreatic cancer by inducing MDM2 ubiquitination degradation.
Han A, Liu J, Du P, Li W, Quan H, Lin Z, Chen L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156298
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156298
Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
Wang ZQ, Wu ZX, Chen JW, Li HF, Wu HD, Bao JX, Cheng Y, Dai YW, Wang OC, Dai XX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156287
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156287
FAM49B drives colorectal cancer progression by stabilizing c-Myc through NEK9 phosphorylation.
Lu C, Liu T, Yimin E, Miao L, Yu C, Zhang J, Luo X
BioFactors (Oxford, England) 2025 Jan-Feb;51(1):e2158
BioFactors (Oxford, England) 2025 Jan-Feb;51(1):e2158
RNF112, whose transcription is regulated by KLF4, inhibits colorectal cancer growth via promoting ubiquitin-dependent degradation of NAA40.
Li C, Guan W, Geng D, Feng Y
Cell biology and toxicology 2025 Jan 6;41(1):22
Cell biology and toxicology 2025 Jan 6;41(1):22
Shanyao regulates the PI3K/AKT/P21 pathway to promote oogonial stem cell proliferation and stemness restoration to alleviate premature ovarian insufficiency.
Zou Y, Li Z, Lin Y, Zheng Y, Liu Z, Li Y, Huang L, Chen Z, Zhu L
Journal of ethnopharmacology 2025 Jan 31;340:119168
Journal of ethnopharmacology 2025 Jan 31;340:119168
Ubiquitin-conjugating enzyme E2T confers chemoresistance of colorectal cancer by enhancing the signal propagation of Wnt/β-catenin pathway in an ERK-dependent manner.
Liu B, Liu R, Zhang X, Tian L, Li Z, Yu J
Chemico-biological interactions 2025 Jan 25;406:111347
Chemico-biological interactions 2025 Jan 25;406:111347
Identification of KRT16 and ANXA10 as cell cycle regulation genes for lung adenocarcinoma based on self-transcriptome sequencing of surgical samples and TCGA public data mining.
Liu WJ, Shen JP, Zhang RQ, Fan XY
Discover oncology 2025 Jan 22;16(1):78
Discover oncology 2025 Jan 22;16(1):78
TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination.
Yu C, Zhang C, Zhang Q, Zhang C, Han J, Li J
iScience 2025 Jan 17;28(1):111590
iScience 2025 Jan 17;28(1):111590
Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma.
Chen L, Wu L, Tang M, Cheng Y, Wang K, Zhang J, Deng W, Zhu L, Chen J
BMC urology 2025 Jan 16;25(1):8
BMC urology 2025 Jan 16;25(1):8
Zuogui pills ameliorate chemotherapy-induced ovarian aging by improving stemness, regulating cell cycle and reducing apoptosis of oogonial stem cells via the Notch1/Nrf2 pathway.
Li Z, Lin Y, Zou Y, Liang Y, Zeng L, Wang Y, Li Y, Zong Y, Zhang Y, Zheng Y, Cui Y, Huang L, Chen Z, Pan X, Zhu L
Journal of ethnopharmacology 2025 Jan 13;339:119105
Journal of ethnopharmacology 2025 Jan 13;339:119105
Regulation of the β‑catenin/LEF‑1 pathway by the siRNA knockdown of RUVBL1 expression inhibits breast cancer cell proliferation, migration and invasion.
Zhang X, Cui D, Sun W, Yang G, Wang W, Mi C
Oncology reports 2025 Feb;53(2)
Oncology reports 2025 Feb;53(2)
Ilicicolin C suppresses the progression of prostate cancer by inhibiting PI3K/AKT/mTOR pathway.
Gan X, Luo X, Chen J, Fang W, Nie M, Lu H, Liu Y, Wang X
Molecular and cellular biochemistry 2025 Feb;480(2):1089-1104
Molecular and cellular biochemistry 2025 Feb;480(2):1089-1104
Synthesis of novel deuterated EGFR/ALK dual-target inhibitors and their activity against non-small cell lung cancer.
Nie H, Zhang S, Wang L, Wang M, Qiu J, Jia F, Li X, Tian G, An B
European journal of medicinal chemistry 2025 Feb 5;283:117146
European journal of medicinal chemistry 2025 Feb 5;283:117146
The Unveiled Novel regulator of Adeno-associated virus production in HEK293 cells.
Yan J, Li Z, Shu Y, Chen H, Wang T, Li X, Zhang Y, Li L, Zhang Y
Gene 2025 Feb 20;938:149122
Gene 2025 Feb 20;938:149122
Unbalanced occlusal loading elicited remodeling responses in growing rat temporomandibular joints and Notch1/Hes1 signaling pathway expression.
Xiao M, Yue Q, Qin Z, Hang X, Chen X, Ni S
BMC oral health 2025 Feb 19;25(1):267
BMC oral health 2025 Feb 19;25(1):267
Aqueous extract of Cornus officinalis alleviate NAFLD via protecting hepatocytes proliferation through regulation of the tricarboxylic acid cycle.
Liu B, Shao T, Xiao D, Yang S, Lin W, Sun L, Zhang W, Luo M, Zhao J, Yang L, Bai S, Deng D, Wang C, Wang S, Zhang R, Liu Z, An L
Journal of ethnopharmacology 2025 Feb 11;341:119330
Journal of ethnopharmacology 2025 Feb 11;341:119330
B7-H3 enhances the malignant phenotype of colorectal cancer by activating the Wnt/β-catenin pathway mediated by CYP1B1.
Liu X, Ding J, Zong Q, Mao Y
Tissue & cell 2025 Dec;97:103066
Tissue & cell 2025 Dec;97:103066
TTK Defines a High-Risk Oral Squamous Cell Carcinoma Subtype Through Dual mTORC1/NF-κB Activation.
Jin H, Liu T, Guo Y, Bu W, Liu F, Hou Y
International dental journal 2025 Dec;75(6):103945
International dental journal 2025 Dec;75(6):103945
Exosome-mediated perturbation of the immune-bone metabolism axis: a mechanistic investigation into bone loss in a simulated microgravity environment.
Yang F, Chen C, Yang C, Chen R, Liu Z, Wen L, Xiao H, Zhou L, Geng B, Xia Y
Artificial cells, nanomedicine, and biotechnology 2025 Dec;53(1):494-513
Artificial cells, nanomedicine, and biotechnology 2025 Dec;53(1):494-513
Bovine tubulin cofactor D (TBCD) disrupts tubulin dimers and inhibits tumor growth via the TNF-α signaling pathways-mediated ROS production.
Wang H, Guo J, Yang J, Wu X, Wu F, Wu H, Zhan Y, Zhang H
International journal of biological macromolecules 2025 Dec;334(Pt 1):148987
International journal of biological macromolecules 2025 Dec;334(Pt 1):148987
The suprachiasmatic nucleus regulates brown fat thermogenesis in male mice through an adrenergic receptor ADRB3-S100B signaling pathway.
Zeng Y, Song X, Chen Q, Gu Y, Zhang J, Zhou T, Li Z, Wang T, Chang L, Yao H, Wang Y, Miao L, Qian L, Guo T, Zhang Y, Rodriguez-Fernandez S, Vidal-Puig A, Xu Y
PLoS biology 2025 Dec;23(12):e3003534
PLoS biology 2025 Dec;23(12):e3003534
Terpine-4-ol alleviates lipopolysaccharide-induced intestinal injury in weaned piglets by regulating intestinal epithelial cell homeostasis via the Wnt/β-catenin signaling pathway.
Dong L, Zhou Y, Wang M, Yuan Q, Qiu G, Liu J, Wang H, Wu A, Yu L, Chen D
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Dec;23:178-190
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Dec;23:178-190
The RNA-binding protein Quaking modulates cell proliferation through the SFRP1 mediated Wnt signaling pathway in NIH3T3 fibroblasts.
Ma B, Gao D, Han G, Zhang H, Yang W, Tao Y, Liu W, Tang K, Wang A, Jin Y, Chen H
Cellular signalling 2025 Dec;136:112102
Cellular signalling 2025 Dec;136:112102
UBE2M inhibits neoplastic cell proliferation via MKK7-JNK-EGR1 axis in melanoma.
Xu L, Pan C, Wang Y, Ni L, Zeng P, Lin X, Lyu X, Huang S, Dang N
Journal of translational medicine 2025 Dec 8;24(1):52
Journal of translational medicine 2025 Dec 8;24(1):52
Multi-omics analysis reveals that ALYREF-mediated m(5)C modification promotes platinum resistance in ovarian cancer via the NSUN2/ALYREF/LGR4 axis.
Yang S, He P, Wang W, Xu X, Xi X, Li Y
Cell death & disease 2025 Dec 5;17(1):77
Cell death & disease 2025 Dec 5;17(1):77
LGR5 interacts with HSP90AB1 to mediate enzalutamide resistance by activating the WNT/β-catenin/AR axis in prostate cancer.
Gao Z, Xiong Z, Tao Y, Wang Q, Guo K, Xu K, Huang H
Chinese medical journal 2025 Dec 5;138(23):3184-3194
Chinese medical journal 2025 Dec 5;138(23):3184-3194
Bruceine D promotes TNBC regression by inhibiting M2-like tumor-associated macrophage polarization induced Wnt3a/β-catenin pathway.
Ma Y, Cao D, Han X, Hu Z, Ding X, Wang J
International immunopharmacology 2025 Dec 3;166:115596
International immunopharmacology 2025 Dec 3;166:115596
Targeting TRIM15-mediated Axin1 depolymerization suppresses Wnt signaling and inhibits colorectal cancer growth.
Liang H, Zheng F, Wu J, Zhou H, Sun Z, Zhang P, Wu W, Zhu G
Cell death & disease 2025 Dec 29;17(1):152
Cell death & disease 2025 Dec 29;17(1):152
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
Chen YM, Huo YX, Wei WS, Liu YX, Wang SH, Jiang L, Rong-He, Zhang HL, Jiang LH
Scientific reports 2025 Dec 29;15(1):44684
Scientific reports 2025 Dec 29;15(1):44684
Shikonin inhibits multiple tumor malignant phenotypes and is associated with Hedgehog pathway downregulation in lung adenocarcinoma.
Wang HG, Lu MX, Sheng ML, Lou YB, Xiao YC, Guo A, Yu ZH
Scientific reports 2025 Dec 24;15(1):44516
Scientific reports 2025 Dec 24;15(1):44516
Targeting intrinsically disordered nuclear protein 1 (NUPR1) with single-domain antibodies alleviates triple-negative breast cancer (TNBC) progression in vivo.
Wang T, Wang M, Chen X, Yin Y, Xu J, Sun Y, Wu A, Liu Z, Ma Z
Cell death & disease 2025 Dec 22;16(1):913
Cell death & disease 2025 Dec 22;16(1):913
GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.
Dong C, Gao Z, Li X
Journal of translational medicine 2025 Dec 2;23(1):1369
Journal of translational medicine 2025 Dec 2;23(1):1369
Evaluation of the clinical characteristics and potentially prognostic factors in HER2-positive breast cancer.
Shi L, Xi PW, Li Z, Wu J, Zhang X, Zhang L
Amino acids 2025 Dec 16;58(1):4
Amino acids 2025 Dec 16;58(1):4
Synthesis, molecular modeling, biological and pharmacokinetic evaluation of hydroxy pyrimidinones and pyrimidinediones as novel LDHA inhibitors.
Sharma H, Elliott T, Good A, Sharma P, Mondal S, Luckett Chastain L, Ihnat MA
European journal of medicinal chemistry 2025 Dec 15;300:118156
European journal of medicinal chemistry 2025 Dec 15;300:118156
Repetitive unidirectional spinal tactile stimulation engages microglial Bmal1 pathways to promote synaptic remodeling in the mPFC of adolescent VPA-exposed mice.
Chen YN, Zhao ST, Hu MA, Li W, Yu J, Ma MJ, Tang LY, Feng X, Li JS, Zhang YX
Journal of neuroinflammation 2025 Dec 11;23(1):23
Journal of neuroinflammation 2025 Dec 11;23(1):23
Knockdown of MiD49 and MiD51 alleviates collagen-induced arthritis and suppresses mitophagy and fatty acid oxidation (FAO) in rheumatoid arthritis fibroblast-like synoviocytes.
Liu J, Zhang C, Ma R, Yin C, Ren J, Yang S, Zhao Y, Tang Y, Wei J, Li X
Free radical biology & medicine 2025 Dec 1;240:514-531
Free radical biology & medicine 2025 Dec 1;240:514-531
FTO curbs trophoblast cell biological behaviors through repressing ALDH1A1 expression.
Liu L, Liu H, Jia R, Zhang X, Lu X
Cytotechnology 2025 Aug;77(4):124
Cytotechnology 2025 Aug;77(4):124
Dujieqing decoction suppresses multiple myeloma growth by inhibiting the Wnt/β-catenin pathway.
Jiawei XU, Haisong LU, Yushi S, Yu L, Xueping LI, Weimin C
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Aug;45(4):720-729
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Aug;45(4):720-729
The LINC01315-encoded small protein YAPer-ORF competes with PRP4k to hijack YAP signaling to aberrantly promote cell growth.
Xie Z, Li C, Huang R, Wu B, Huang Q, Zhang Z, Zhao T, Wu L, Li C, Shen J, Wang H
Cell death and differentiation 2025 Aug;32(8):1428-1440
Cell death and differentiation 2025 Aug;32(8):1428-1440
NUTF2 Promotes Proliferation of Oral Squamous Cell Carcinoma Through PI3K/AKT Signaling Pathway.
Chen Z, Zhao Z, Xu T, Zou F, Yang Y, Lu P, Chen Y, Zhu Z, He Y, Wu Y, Ding X, Song X
Oral diseases 2025 Aug;31(8):2441-2455
Oral diseases 2025 Aug;31(8):2441-2455
PIMREG modulation of PI3K/Akt pathway enhances sorafenib resistance in Huh7 cells.
Zhang L, Gao A, Peng K
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2025 Aug;26(3):241-249
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2025 Aug;26(3):241-249
SETD2 drives METTL14-mediated m(6)A to suppress Piezo1 Attenuation and activate TGM2 to promote pulmonary hypertension.
Zhao SS, Yuan C, Liu JL, Wu QC, Zhou XL
Cellular and molecular life sciences : CMLS 2025 Aug 8;82(1):302
Cellular and molecular life sciences : CMLS 2025 Aug 8;82(1):302
Non-SMC condensin I complex subunit H promotes cell proliferation and inhibits cell apoptosis of clear cell renal cell carcinoma by activating the PI3K/AKT pathway.
Ha H, Wang J, Zhang X, Du Y, Xiong W, Li S, Shang P
Translational andrology and urology 2025 Aug 30;14(8):2153-2170
Translational andrology and urology 2025 Aug 30;14(8):2153-2170
Overexpression of FOS enhances the malignant potential of eutopic endometrial stromal cells in patients with endometriosis‑associated ovarian cancer.
Chen J, He K, Li X, Wang M, Yang Z, Wang Z, Wang K, Jiang W, Zhao L, Cui M
Oncology reports 2025 Apr;53(4)
Oncology reports 2025 Apr;53(4)
Design, synthesis and antitumor activity evaluation of novel modified 18β-glycyrrhetinate derivatives as PPARγ agonists.
Lin H, Cui S, Xu X, Chen Q, Ge J, Ai D, Zhu J, Tao Y, Wang L, Ruan L, Ge W
Bioorganic chemistry 2025 Apr;157:108307
Bioorganic chemistry 2025 Apr;157:108307
EGCG inhibits tobacco smoke-promoted proliferation of lung cancer cells through targeting CCL5.
Dong Z, Wu J, He L, Xie C, Geng S, Wu J, Ji X, Chen X, Zhong C, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156512
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156512
GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy.
Du L, Liu S, Lu Y, Ren D, Yu X, Hu Y, Yang T, Yang Q, Ming J, Zhang J, Yin X, Lu Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2407462
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2407462
Simultaneous cyclin D1 overexpression and p27(kip1) knockdown enable robust Müller glia cell cycle reactivation in uninjured mouse retina.
Wu Z, Liao B, Ying J, Keung J, Zheng Z, Ahola V, Xiong W
eLife 2025 Apr 3;13
eLife 2025 Apr 3;13
THBS2-producing matrix CAFs promote colorectal cancer progression and link to poor prognosis via the CD47-MAPK axis.
Liu Z, Ba Y, Shan D, Zhou X, Zuo A, Zhang Y, Xu H, Liu S, Liu B, Zhao Y, Weng S, Wang R, Deng J, Luo P, Cheng Q, Hu X, Yang S, Wang F, Han X
Cell reports 2025 Apr 22;44(4):115555
Cell reports 2025 Apr 22;44(4):115555
EPHA5 promotes cell proliferation and inhibits apoptosis in Follicular Thyroid Cancer via the STAT3 signaling pathway.
Wang G, Xu G, Fan Y, Wang G, Xu J, Zhang N, Chen J, Chen H, Li Z, Cao X, Zhao Y
Oncogenesis 2025 Apr 22;14(1):12
Oncogenesis 2025 Apr 22;14(1):12
A novel feedback regulation loop of METTL11A-MAFG-NPL4 promotes bladder cancer cell proliferation and tumor progression.
Lu BS, Liu KL, Yin YW, Zhang YP, Qi JC, Zhao CM, Niu YL, Guo PY, Li W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70466
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70466
CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy.
Gao X, Liu F, Zhang B, Ren T, Zheng Y, Niu Z, Ren H, Liu C, Jiang C, Wang C, Huang H, Ma L, Sun Q
Cell death & disease 2025 Apr 11;16(1):276
Cell death & disease 2025 Apr 11;16(1):276
Pulsatilla saponin D inhibited the growth of osteosarcoma by regulating the JNK/ATF3 signaling pathway.
Jin K, Shen C, Yu W, Lin J, Zhu J, Tao H, Liu B
Chemico-biological interactions 2025 Apr 1;410:111420
Chemico-biological interactions 2025 Apr 1;410:111420
The anti-tumor activity of tangeretin in esophageal squamous cell carcinoma by inhibiting GLI2-mediated transcription of GPNMB.
Yang D, Zhang Q, Kuang H, Liu J, Wu S, Wei L, Yao W
PloS one 2024;19(6):e0291531
PloS one 2024;19(6):e0291531
ADAR1 plays a protective role in proximal tubular cells under high glucose conditions by attenuating the PI3K/AKT/mTOR signaling pathway.
Wang Y, Chang J, Wang F, Lai L, Yang S, Fu Y, Ma X, Yun C
Open medicine (Warsaw, Poland) 2024;19(1):20241037
Open medicine (Warsaw, Poland) 2024;19(1):20241037
KRT80 Promotes Lung Adenocarcinoma Progression and Serves as a Substrate for VCP.
Huang S, Tong W, Yang B, Ma L, Zhang J, Wang C, Xu L, Mei J
Journal of Cancer 2024;15(8):2229-2244
Journal of Cancer 2024;15(8):2229-2244
Apolipoprotein L3 inhibits breast cancer proliferation and modulates cell cycle via the P53 pathway.
Yu H, Li S, Li X, Liu Y, Wang Z, Cui M, Jin F, Yu X
Journal of Cancer 2024;15(14):4623-4635
Journal of Cancer 2024;15(14):4623-4635
TXNDC12 inhibits pancreatic tumor cells ferroptosis by regulating GSH/GGT7 and promotes its growth and metastasis.
Xu X, Hei Y, Wang B, Tian S, Chen X, Zhang J, Wang F
Journal of Cancer 2024;15(12):3913-3929
Journal of Cancer 2024;15(12):3913-3929
PSAT1 mediated EMT of colorectal cancer cells by regulating Pl3K/AKT signaling pathway.
Wang M, Zhang H, Lu Z, Su W, Tan Y, Wang J, Jia X
Journal of Cancer 2024;15(10):3183-3198
Journal of Cancer 2024;15(10):3183-3198
B4 suppresses lymphoma progression by inhibiting fibroblast growth factor binding protein 1 through intrinsic apoptosis.
Varier KM, Dan G, Li X, Liu W, Jiang F, Linghu KG, Li Y, Ben-David Y, Zhang N, Xiao C, Gajendran B, Shen X
Frontiers in pharmacology 2024;15:1408389
Frontiers in pharmacology 2024;15:1408389
Development of an anoikis-related gene signature and prognostic model for predicting the tumor microenvironment and response to immunotherapy in colorectal cancer.
Li C, Weng J, Yang L, Gong H, Liu Z
Frontiers in immunology 2024;15:1378305
Frontiers in immunology 2024;15:1378305
Comprehensive analysis of ferroptosis-related genes indicates that TRIM46 is a novel biomarker and promotes the progression of ovarian cancer via modulating ferroptosis and Wnt signaling pathway.
Liu S, Xiao C, Rong Y, Liu M, Yang K, Tang J, Wang Z
American journal of cancer research 2024;14(10):4686-4707
American journal of cancer research 2024;14(10):4686-4707
MK8722 initiates early-stage autophagy while inhibiting late-stage autophagy via FASN-dependent reprogramming of lipid metabolism.
Wang L, Zhu H, Shi Z, Chen B, Huang H, Lin G, Li J, Yu H, Xu S, Chen G, Ou R, Dai C
Theranostics 2024;14(1):75-95
Theranostics 2024;14(1):75-95
The long noncoding RNA MIR4435-2HG enhances the migration, promotion, and glycolysis of nonsmall cell lung cancer cells by targeting the miR-371a-5p/SOX2/PI3K/Akt axis.
Yang J, Su Y, Wang Y, Gao K, Li C, Li M
SAGE open medicine 2024;12:20503121241289290
SAGE open medicine 2024;12:20503121241289290
A potent new-scaffold androgen receptor antagonist discovered on the basis of a MIEC-SVM model.
Wang XY, Chai X, Shan LH, Xu XH, Xu L, Hou TJ, Sun HY, Li D
Acta pharmacologica Sinica 2024 Sep;45(9):1978-1991
Acta pharmacologica Sinica 2024 Sep;45(9):1978-1991
Alternative splicing of ALDOA confers tamoxifen resistance in breast cancer.
Yu S, Wu R, Si Y, Fan Z, Wang Y, Yao C, Sun R, Xue Y, Chen Y, Wang Z, Dong S, Wang N, Ling X, Liang Z, Bi C, Yang Y, Dong W, Sun H
Oncogene 2024 Sep;43(39):2901-2913
Oncogene 2024 Sep;43(39):2901-2913
TTYH3 Promotes Cervical Cancer Progression by Activating the Wnt/β-Catenin Signaling Pathway.
Huang X, Li Q, Zheng X, Jiang C
Cancer investigation 2024 Sep;42(8):726-739
Cancer investigation 2024 Sep;42(8):726-739
α-Ketoglutarate promotes cardiomyocyte proliferation and heart regeneration after myocardial infarction.
Shi Y, Tian M, Zhao X, Tang L, Wang F, Wu H, Liao Q, Ren H, Fu W, Zheng S, Jose PA, Li L, Zeng C
Nature cardiovascular research 2024 Sep;3(9):1083-1097
Nature cardiovascular research 2024 Sep;3(9):1083-1097
PSMD11 promotes the proliferation of hepatocellular carcinoma by regulating the ubiquitination degradation of CDK4.
Sun L, Liu Z, Wu Z, Wu Z, Qiu B, Liu S, Hu J, Yin X
Cellular signalling 2024 Sep;121:111279
Cellular signalling 2024 Sep;121:111279
USP22 is required for human endometrial stromal cell proliferation and decidualization by deubiquitinating FoxM1.
Zhou M, Gao Y, Wu S, Wang Y, Yang J
Cellular signalling 2024 Sep;121:111265
Cellular signalling 2024 Sep;121:111265
SFRP1 reduces neutrophil infiltration and inhibits the Wnt/β-catenin pathway to alleviate oral submucous fibrosis.
Zhou R, Yin L, Zhang X, Zhu K
In vitro cellular & developmental biology. Animal 2024 Oct;60(9):1034-1045
In vitro cellular & developmental biology. Animal 2024 Oct;60(9):1034-1045
MIA3 promotes the degradation of GSH (glutathione) by binding to CHAC1, thereby promoting the progression of hepatocellular carcinoma.
Wanbiao Z, Jing M, Shi Z, Tengxiang C, Xueke Z, Haiyang L
Molecular and cellular biochemistry 2024 Oct;479(10):2769-2784
Molecular and cellular biochemistry 2024 Oct;479(10):2769-2784
Evaluation of 3-O-β-D-galactosylated resveratrol-loaded polydopamine nanoparticles for hepatocellular carcinoma treatment.
Shan X, Lv S, Cheng H, Zhou L, Gao Y, Xing C, Li D, Tao W, Zhang C
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2024 Oct;203:114454
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2024 Oct;203:114454
Rho GTPase activating protein 11A promotes tongue squamous cell carcinoma proliferation and is a transcriptional target of forkhead box M1.
Zhang W, Bai X, Liu T, Mao Y, Zhang L, Wang W, Yu H
Journal of dental sciences 2024 Oct;19(4):2268-2277
Journal of dental sciences 2024 Oct;19(4):2268-2277
EREG silencing inhibits tumorigenesis via inactivating ERK/p38 MAPK pathway in pancreatic ductal adenocarcinoma.
Liu F, Wu W, Cao W, Feng L, Yuan J, Ren Z, Dai N, Wang X, Li X, Yue S
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167336
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167336
The expression and role of SUZ12 in lung adenocarcinoma.
Hu X, Hu C, Zhong P
Cancer medicine 2024 Oct;13(19):e70190
Cancer medicine 2024 Oct;13(19):e70190
N-acetylgalactosaminyltransferase GALNT6 is a potential therapeutic target of clear cell renal cell carcinoma progression.
Sun L, Li Z, Shu P, Lu M
Cancer science 2024 Oct;115(10):3320-3332
Cancer science 2024 Oct;115(10):3320-3332
Zuogui Pills alleviate cyclophosphamide-induced ovarian aging by reducing oxidative stress and restoring the stemness of oogonial stem cells through the Nrf2/HO-1 signaling pathway.
Li Z, Liang Y, Wang Y, Lin Y, Zeng L, Zhang Y, Zhu L
Journal of ethnopharmacology 2024 Oct 28;333:118505
Journal of ethnopharmacology 2024 Oct 28;333:118505
PTPN11 is a potential biomarker for type 2 diabetes mellitus complicated with colorectal cancer.
Sun M, Han Z, Luo Z, Ge L, Zhang X, Feng K, Zhang G, Xu F, Zhou H, Han H, Jiang W
Scientific reports 2024 Oct 24;14(1):25155
Scientific reports 2024 Oct 24;14(1):25155
A quinoline-2-thione derivative as a novel chemotherapy drug candidate displays anti-tumor activity in vitro and in vivo.
Zhao JJ, Zhao J, Lin F, Xu LL, Chen ZG, Jiang YQ, Zhao GA
BMC cancer 2024 Oct 13;24(1):1272
BMC cancer 2024 Oct 13;24(1):1272
DEAD/H-box helicase 11 is transcriptionally activated by Yin Yang-1 and accelerates oral squamous cell carcinoma progression.
Yang G, Shi X, Zhang M, Wang K, Tian X, Wang X
Cell biology international 2024 Nov;48(11):1731-1742
Cell biology international 2024 Nov;48(11):1731-1742
NSUN2 regulates Wnt signaling pathway depending on the m5C RNA modification to promote the progression of hepatocellular carcinoma.
Xing H, Gu X, Liu Y, Xu L, He Y, Xue C
Oncogene 2024 Nov;43(47):3469-3482
Oncogene 2024 Nov;43(47):3469-3482
Hepatocyte-Specific HuR Protects Against Acetaminophen-Induced Liver Injury in Mice.
Lu L, Chen J, Jiang H, Li N, Li X, Liu Y, Zong C
Journal of cellular and molecular medicine 2024 Nov;28(22):e70246
Journal of cellular and molecular medicine 2024 Nov;28(22):e70246
Talaketides A-G, linear polyketides with prostate cancer cytotoxic activity from the mangrove sediment-derived fungus Talaromyces sp. SCSIO 41027.
Chen C, Wang X, Fang W, Liang J, Cai J, Yang D, Luo X, Gao C, Yi X, Liu Y, Zhou X
Chinese journal of natural medicines 2024 Nov;22(11):1047-1056
Chinese journal of natural medicines 2024 Nov;22(11):1047-1056
Sterile Alpha Motif Domain-Containing 5 Suppresses Malignant Phenotypes and Tumor Growth in Breast Cancer: Regulation of Polo-Like Kinase 1 and c-Myc Signaling in a Xenograft Model.
Tuo Y, Ye Y
Cureus 2024 Nov;16(11):e73259
Cureus 2024 Nov;16(11):e73259
ZNF652 exerts a tumor suppressor role in lung cancer by transcriptionally downregulating cyclin D3.
Xie C, Zhou X, Wu J, Chen W, Ren D, Zhong C, Meng Z, Shi Y, Zhu J
Cell death & disease 2024 Nov 5;15(11):792
Cell death & disease 2024 Nov 5;15(11):792
Erianin inhibits the progression of DDP-resistant lung adenocarcinoma by regulating the Wnt/β-catenin pathway and activating the caspase-3 for apoptosis in vitro and in vivo.
Tang L, Ruan Y, Wang B, Zhang M, Xue J, Wang T
Hereditas 2024 Nov 27;161(1):48
Hereditas 2024 Nov 27;161(1):48
Dapagliflozin suppressed gastric cancer growth via regulating OTUD5 mediated YAP1 deubiquitination.
Ren K, Wang X, Ma R, Chen H, Min T, Ma Y, Xie X, Wang W, Deng X, Zhou Z, Li K, Zhu K, Hao N, Dang C, Sun T, Zhang H
European journal of pharmacology 2024 Nov 15;983:177002
European journal of pharmacology 2024 Nov 15;983:177002
Inhibition of mitochondrial OMA1 ameliorates osteosarcoma tumorigenesis.
Chen L, Chen D, Pan Y, Mo Y, Lai B, Chen H, Zhang DW, Xia XD
Cell death & disease 2024 Nov 1;15(11):786
Cell death & disease 2024 Nov 1;15(11):786
Dihydroartemisinin-driven selective anti-lung cancer proliferation by binding to EGFR and inhibition of NRAS signaling pathway-induced DNA damage.
Li LG, Peng XC, Yang ZY, Han N, Gou CL, Shi J, Yu LL, Chen NN, Yu TT, Li TF, Li XY, Hu J
Scientific reports 2024 May 22;14(1):11704
Scientific reports 2024 May 22;14(1):11704
Allosteric SHP2 inhibition enhances regorafenib's effectiveness in colorectal cancer treatment.
Han X, Wang W, Wang R, Zhang W, Zhu L, Xu Q, Guo W, Gu Y
Biochemical and biophysical research communications 2024 May 21;709:149812
Biochemical and biophysical research communications 2024 May 21;709:149812
MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer.
Zheng SM, Feng YC, Zhu Q, Li RQ, Yan QQ, Teng L, Yue YM, Han MM, Ye K, Zhang SN, Qi TF, Tang CX, Zhao XH, Zhang YY, Xu L, Xu R, Xing J, Baker M, Liu T, Thorne RF, Jin L, Preiss T, Zhang XD, Cang S, Gao JN
Cancer research 2024 May 2;84(9):1460-1474
Cancer research 2024 May 2;84(9):1460-1474
Combined SET7/9 and CDK4 inhibition act synergistically against osteosarcoma.
Shi Y, Wang Z, Shao Y, Guang Q, Zhang J, Liu B, Wu C, Wang Y, Sui P
Biochemical and biophysical research communications 2024 May 14;708:149808
Biochemical and biophysical research communications 2024 May 14;708:149808
A novel disulfide death-related genes prognostic signature identifies the role of IPO4 in glioma progression.
Wu H, Yang Z, Chang C, Wang Z, Zhang D, Guo Q, Zhao B
Cancer cell international 2024 May 11;24(1):168
Cancer cell international 2024 May 11;24(1):168
Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping.
Hao DJ, Qin Y, Zhou SJ, Dong BH, Yang JS, Zou P, Wang LP, Zhao YT
Journal of pharmaceutical analysis 2024 Mar;14(3):335-347
Journal of pharmaceutical analysis 2024 Mar;14(3):335-347
METTL3-mediated m(6)A modification of SOX4 regulates osteoblast proliferation and differentiation via YTHDF3 recognition.
Feng ZW, Peng B, Wang SH, Zhao DC, Wang YB, Yang A, Zhan HW, Sheng XY, Xu LH, Ren XJ, Yang F, Geng B, Xia YY
Cellular signalling 2024 Mar;115:111038
Cellular signalling 2024 Mar;115:111038
The mechanism of Chebulae Fructus Immaturus promote diabetic wound healing based on network pharmacology and experimental verification.
Qiu F, Fan S, Diao Y, Liu J, Li B, Li K, Zhang W
Journal of ethnopharmacology 2024 Mar 25;322:117579
Journal of ethnopharmacology 2024 Mar 25;322:117579
YTHDF1 Promotes Proliferation and Inhibits Apoptosis of Gastric Cancer Cells via Upregulating TCF7 mRNA Translation.
Li Y, Guo X, Liang X, Wang Z
Frontiers in bioscience (Landmark edition) 2024 Mar 20;29(3):117
Frontiers in bioscience (Landmark edition) 2024 Mar 20;29(3):117
FTO demethylates regulates cell-cycle progression by controlling CCND1 expression in luteinizing goat granulosa cells.
Li D, Zhou L, Liu Z, Zhang Z, Mao W, Shi W, Zhu M, Wang F, Wan Y
Theriogenology 2024 Mar 1;216:20-29
Theriogenology 2024 Mar 1;216:20-29
Lentinan mitigates pemetrexed chemoresistance by the PI3K/Akt pathway in non-small cell lung cancer.
Tian P, Du D, Yang L, Zhou N, Tao L
Cell biochemistry and biophysics 2024 Jun;82(2):1421-1431
Cell biochemistry and biophysics 2024 Jun;82(2):1421-1431
p16 and p53 can Serve as Prognostic Markers for Head and Neck Squamous Cell Carcinoma.
Wang Y, Wang F, Wang S, Zhang L, Fu H, Sun L, Wang W, Liu C, Ren W, Gao L, Xing G, Ma X
International dental journal 2024 Jun;74(3):543-552
International dental journal 2024 Jun;74(3):543-552
Anti-pancreatic cancer activity of cassane diterpenoids isolated from the seeds of Caesalpinia sappan mediated by autophagy activation via ROS/AMPK/mTORC1 pathway.
Su J, Wang DS, Hu GX, Liu YY, Hu M, Chen Y, Wang QQ, Yan RC, Wu Y, Li YJ, Ma K, Qi YY, Ding LF, Wu XD
Phytochemistry 2024 Jun;222:114105
Phytochemistry 2024 Jun;222:114105
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway.
Wu X, Fu Y, Ma J, Li C, He A, Zhang T
Tissue engineering and regenerative medicine 2024 Jul;21(5):791-807
Tissue engineering and regenerative medicine 2024 Jul;21(5):791-807
HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis.
Zhang H, Han B, Tian S, Gong Y, Chen L, Liu L
Aging 2024 Jul 9;16(13):11103-11116
Aging 2024 Jul 9;16(13):11103-11116
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Zhang G, Zeng C, Sun X, Zhang Q, Wang Y, Xia R, Mai Q, Xue G, Huang H, Wang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
Hydrogel loaded with thiolated chitosan modified taxifolin liposome promotes osteoblast proliferation and regulates Wnt signaling pathway to repair rat skull defects.
Ding Q, Liu W, Zhang S, Sun S, Yang J, Zhang L, Wang N, Ma S, Chai G, Shen L, Gao Y, Ding C, Liu X
Carbohydrate polymers 2024 Jul 15;336:122115
Carbohydrate polymers 2024 Jul 15;336:122115
A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC.
Goto Y, Koshizuka K, Ando T, Izumi H, Wu X, Sato K, Ishikawa T, Ford K, Feng X, Wang Z, Arang N, Allevato MM, Kishore A, Mali P, Gutkind JS
Cancer research communications 2024 Jul 1;4(7):1850-1862
Cancer research communications 2024 Jul 1;4(7):1850-1862
FOLR1-stabilized β-catenin promotes laryngeal carcinoma progression through EGFR/AKT/GSK-3β pathway.
Tuo H, Li X, Du H, Li M, Xu C, Yu Z, Zhao H
Molecular carcinogenesis 2024 Jan;63(1):34-44
Molecular carcinogenesis 2024 Jan;63(1):34-44
Metformin: A promising clinical therapeutical approach for BPH treatment via inhibiting dysregulated steroid hormones-induced prostatic epithelial cells proliferation.
Yang T, Yuan J, Peng Y, Pang J, Qiu Z, Chen S, Huang Y, Jiang Z, Fan Y, Liu J, Wang T, Zhou X, Qian S, Song J, Xu Y, Lu Q, Yin X
Journal of pharmaceutical analysis 2024 Jan;14(1):52-68
Journal of pharmaceutical analysis 2024 Jan;14(1):52-68
Transcriptomics and molecular docking reveal the potential mechanism of lycorine against pancreatic cancer.
Zhou X, Guo Z, Liu S, Chen Z, Wang Y, Yang R, Li X, Ma K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155128
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155128
IGF2BP2 Drives Cell Cycle Progression in Triple-Negative Breast Cancer by Recruiting EIF4A1 to Promote the m6A-Modified CDK6 Translation Initiation Process.
Xia T, Dai XY, Sang MY, Zhang X, Xu F, Wu J, Shi L, Wei JF, Ding Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(1):e2305142
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(1):e2305142
Unlocking the role of EIF5A: A potential diagnostic marker regulating the cell cycle and showing negative correlation with immune infiltration in lung adenocarcinoma.
Yang Z, Yuan H, He H, Qi S, Zhu X, Hu X, Jin M, Zhang XX, Yuan ZG
International immunopharmacology 2024 Jan 5;126:111227
International immunopharmacology 2024 Jan 5;126:111227
MiR-199a-5p inhibits dermal papilla cells proliferation by regulating VEGFA expression in cashmere goat.
Zhang T, Zheng Y, Zhang F, Wang X, Du J, Wang X
Gene 2024 Jan 30;893:147901
Gene 2024 Jan 30;893:147901
Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer.
Lian Z, Tian P, Ma S, Chang T, Liu R, Feng Q, Li J
Aging 2024 Jan 24;16(2):1938-1951
Aging 2024 Jan 24;16(2):1938-1951
A transcriptome based molecular classification scheme for cholangiocarcinoma and subtype-derived prognostic biomarker.
Fan Z, Zou X, Wang G, Liu Y, Jiang Y, Wang H, Zhang P, Wei F, Du X, Wang M, Sun X, Ji B, Hu X, Chen L, Zhou P, Wang D, Bai J, Xiao X, Zuo L, Xia X, Yi X, Lv G
Nature communications 2024 Jan 11;15(1):484
Nature communications 2024 Jan 11;15(1):484
Silencing geranylgeranyltransferase I inhibits the migration and invasion of salivary adenoid cystic carcinoma through RhoA/ROCK1/MLC signaling and suppresses proliferation through cell cycle regulation.
Chi Z, Wang Q, Tong L, Qiu J, Yang F, Guo Q, Li W, Zheng J, Chen Z
Cell biology international 2024 Feb;48(2):174-189
Cell biology international 2024 Feb;48(2):174-189
Elafibranor emerged as a potential chemotherapeutic drug for non-muscle invasive bladder cancer.
Wang W, Shan D, Wang G, Mao X, You W, Wang X, Wang Z
Cell insight 2024 Feb;3(1):100149
Cell insight 2024 Feb;3(1):100149
Decreased PDLIM1 expression in endothelial cells contributes to the development of intracranial aneurysm.
Yan Y, Qin X, Zheng Y, Jin T, Hu Y, An Q, Leng B
Vascular medicine (London, England) 2024 Feb;29(1):5-16
Vascular medicine (London, England) 2024 Feb;29(1):5-16
Aurora kinase B disruption suppresses pathological retinal angiogenesis by affecting cell cycle progression.
Zhu W, Gui X, Zhou Y, Gao X, Zhang R, Li Q, Zhang H, Zhao J, Cui X, Gao G, Tang H, Huan C, Pan D, Song H, Zhou Z, Shen W
Experimental eye research 2024 Feb;239:109753
Experimental eye research 2024 Feb;239:109753
Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation.
Li H, Song C, Zhang Y, Liu G, Mi H, Li Y, Chen Z, Ma X, Zhang P, Cheng L, Peng P, Zhu H, Chen Z, Dong M, Chen S, Meng H, Xiao Q, Li H, Wu Q, Wang B, Zhang S, Shu K, Wan F, Guo D, Zhou W, Zhou L, Mao F, Rich JN, Yu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2305620
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2305620
Prognosis and biological function of SGOL1 in clear cell renal cell carcinoma: a multiomics analysis.
Yang Z, Jiang Y, Wang L, Yu B, Cai H, Fan J, Zhang M
BMC medical genomics 2024 Feb 21;17(1):60
BMC medical genomics 2024 Feb 21;17(1):60
Effects of sulforaphane on prostate cancer stem cells-like properties: In vitro and molecular docking studies.
Xuan Y, Xu J, Que H, Zhu J
Archives of biochemistry and biophysics 2024 Dec;762:110216
Archives of biochemistry and biophysics 2024 Dec;762:110216
Circ-RNF111 Promotes Proliferation of Ovarian Cancer Cell SKOV-3 by Targeting the MiR-556-5p/CCND1 Axis.
Zuo L, Tan Y, Xu QL, Li XL, Xiao M
Biochemical genetics 2024 Dec;62(6):4884-4895
Biochemical genetics 2024 Dec;62(6):4884-4895
FOXG1 interaction with SATB2 promotes autophagy to alleviate neuroinflammation and mechanical abnormal pain in rats with lumbar disc herniation.
Wang Z, Gu Y, Wang H, Chen Y, Chen H, Wang X, Yuan W
Annals of medicine 2024 Dec;56(1):2399967
Annals of medicine 2024 Dec;56(1):2399967
Revealing the mechanism of Gualou-Xiebai against myocardial ischemia based on network pharmacology and energy metabolism strategies.
Jiang Q, Wen Y, Chen P, Hong X, Qian R, Liu J, Li J, Huang F, Han L
Biomedical chromatography : BMC 2024 Dec;38(12):e6007
Biomedical chromatography : BMC 2024 Dec;38(12):e6007
Testosterone-Induced H3K27 Deacetylation Participates in Granulosa Cell Proliferation Suppression and Pathogenesis of Polycystic Ovary Syndrome.
Tong X, Hu Z, Zhou H, Zhang Y, Zhang YL, Zhang S, Jin J
The American journal of pathology 2024 Dec;194(12):2326-2340
The American journal of pathology 2024 Dec;194(12):2326-2340
Methyltransferase-Like 3-Driven N6-Methyladenosine Modification of Recombination Signal Binding Protein for Immunoglobulin Kappa J Region Promotes Vascular Remodeling in Pulmonary Hypertension.
Du Q, Zhang C, Qu T, Zhou X, Liu Y, Chen Z, Shen Z, Chen P, Zhang R
The American journal of pathology 2024 Dec;194(12):2252-2271
The American journal of pathology 2024 Dec;194(12):2252-2271
MiR-135b-5p promotes cetuximab resistance in colorectal cancer by regulating FOXN3.
Peng C, Li X, Yao Y, Nie Y, Fan L, Zhu C
Cancer biology & therapy 2024 Dec 31;25(1):2373497
Cancer biology & therapy 2024 Dec 31;25(1):2373497
CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β-catenin signaling pathway.
Wei Z, Xia K, Liu W, Huang X, Wei Z, Guo W
Molecular medicine (Cambridge, Mass.) 2024 Dec 20;30(1):260
Molecular medicine (Cambridge, Mass.) 2024 Dec 20;30(1):260
Network pharmacology and anticancer mechanism study of Dendrobium nobile dendrobine in the treatment of colorectal cancer.
Luo P, Huang C, Guo J, Yao X, Pan C, Bao A, Li F, Li YY
Discover oncology 2024 Dec 18;15(1):768
Discover oncology 2024 Dec 18;15(1):768
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
Gong K, Zheng Y, Liu Y, Zhang T, Song Y, Chen W, Guo L, Zhou J, Liu W, Fang T, Chen Y, Wang J, Pan F, Shi K
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
Upregulation of collagen type X alpha 1 promotes the progress of triple-negative breast cancer via Wnt/β-catenin signaling.
Peng J, Liu X, Mao Y, Lv M, Ma T, Liu J, Zhou Q, Han Y, Li X, Wang H
Molecular carcinogenesis 2024 Aug;63(8):1588-1598
Molecular carcinogenesis 2024 Aug;63(8):1588-1598
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells.
Gao Y, Hou J, Fei X, Ren L, Lu R, Liu P, Liu S, Zhu C, Wang X, Pan Y
Cellular signalling 2024 Aug;120:111227
Cellular signalling 2024 Aug;120:111227
Long non-coding RNA NEAT1 induced by BHLHE40 activates Wnt/β-catenin signaling and potentiates colorectal cancer progression.
Ji A, Li H, Fu X, Zhang Y, Liu Y
Cell division 2024 Aug 4;19(1):25
Cell division 2024 Aug 4;19(1):25
Bacillus subtilis alleviates excessive apoptosis of intestinal epithelial cells in intrauterine growth restriction suckling piglets via the members of Bcl-2 and caspase families.
Xie Z, Yun Y, Yu G, Zhang X, Zhang H, Wang T, Zhang L
Journal of the science of food and agriculture 2024 Aug 30;104(11):6924-6932
Journal of the science of food and agriculture 2024 Aug 30;104(11):6924-6932
N-desmethyldauricine from Menispermum dauricum DC suppresses triple-negative breast cancer growth in 2D and 3D models by downregulating the NF-κB signaling pathway.
Liu W, Yu Y, Hou T, Wei H, Lv F, Shen A, Liu Y, Wang J, Fu D
Chemico-biological interactions 2024 Aug 1;398:111113
Chemico-biological interactions 2024 Aug 1;398:111113
Liensinine inhibits progression of intrahepatic cholangiocarcinoma by regulating TGF-β1 /P-smad3 signaling through HIF-1a.
Zhu X, Bao W, Xie X, Chen B, Li R, Zhao J, Wu L, Yu Z, Li S, Zhu Q, Chen G, Li J
Molecular carcinogenesis 2024 Apr;63(4):772-784
Molecular carcinogenesis 2024 Apr;63(4):772-784
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Du C, Zhao S, Shan T, Han X, Jiang Q, Chen J, Gu L, Wei T, Yang T, Wang S, Wang H, Guo X, Wang L
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Eukaryotic initiation factor 3a promotes the development of diffuse large B-cell lymphoma through regulating cell proliferation.
Sun H, Shang J, Liu X, Ren S, Hu S, Wang X
BMC cancer 2024 Apr 8;24(1):432
BMC cancer 2024 Apr 8;24(1):432
Glutamine Promotes Porcine Intestinal Epithelial Cell Proliferation through the Wnt/β-Catenin Pathway.
Fang YX, Lu EQ, Cheng YJ, Xu E, Zhu M, Chen X
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7155-7166
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7155-7166
CHOP regulated by METTL14-m6A affects cell cycle arrest and regorafenib sensitivity in HCC cells.
Pan Y, You B, Zhao X, Zhang S, Li W
BMC cancer 2024 Apr 25;24(1):525
BMC cancer 2024 Apr 25;24(1):525
DCDC2 inhibits hepatic stellate cell activation and ameliorates CCl(4)-induced liver fibrosis by suppressing Wnt/β-catenin signaling.
Liu QQ, Chen J, Ma T, Huang W, Lu CH
Scientific reports 2024 Apr 24;14(1):9425
Scientific reports 2024 Apr 24;14(1):9425
METTL14 promotes neuroblastoma formation by inhibiting YWHAH via an m6A-YTHDF1-dependent mechanism.
Wang J, Yin H, Li G, Wu D, Xu Y, Chen Y, Wang X, Xing Y, Zhang T, Fei D, Yang P, Fang F, Tao Y, Li X, Yu J, Yang Y, Li Z, Shi L, Zhang Z, Pan J
Cell death discovery 2024 Apr 22;10(1):186
Cell death discovery 2024 Apr 22;10(1):186
B-Myb deficiency boosts bortezomib-induced immunogenic cell death in colorectal cancer.
Hui YJ, Yu TT, Li LG, Peng XC, Di MJ, Liu H, Gu WL, Li TF, Zhao KL, Wang WX
Scientific reports 2024 Apr 2;14(1):7733
Scientific reports 2024 Apr 2;14(1):7733
LAMP5 may promote MM progression by activating p38.
Chen Y, Ma T
Pathology oncology research : POR 2023;29:1611083
Pathology oncology research : POR 2023;29:1611083
Effects of Ginsenoside Rg1 on the Biological Behavior of Human Amnion-Derived Mesenchymal Stem/Stromal Cells (hAD-MSCs).
Ling L, Shu H, Huang Y, Hou J, Hua Y
Stem cells international 2023;2023:7074703
Stem cells international 2023;2023:7074703
P16(INK4a) Regulates ROS-Related Autophagy and CDK4/6-Mediated Proliferation: A New Target of Myocardial Regeneration Therapy.
Sun J, Zhou L, Yang T, Deng B, Bao Y, Gu L, Wang H, Wang L
Oxidative medicine and cellular longevity 2023;2023:1696190
Oxidative medicine and cellular longevity 2023;2023:1696190
Comprehensive Analysis of Sideroflexin 4 in Hepatocellular Carcinoma by Bioinformatics and Experiments.
Du Z, Zhang Z, Han X, Xie H, Yan W, Tian D, Liu M, Rao C
International journal of medical sciences 2023;20(10):1300-1315
International journal of medical sciences 2023;20(10):1300-1315
The Potent Novel CDK4/6 Inhibitor TQB3616 in Hormone Receptor Positive Breast Cancer: Preclinical Characterization with in vitro and Human Tumor Xenograft Models.
Hu W, Wang L, Luo J, Zhang J, Li N
Breast cancer (Dove Medical Press) 2023;15:899-912
Breast cancer (Dove Medical Press) 2023;15:899-912
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Wang M, Zhang Y, Liu M, Jia Y, He J, Xu X, Shi H, Zhang Y, Zhang J, Liu Y
Journal of Cancer 2023;14(4):611-627
Journal of Cancer 2023;14(4):611-627
SHCBP1 Promotes the Proliferation of Breast Cancer Cells by Inhibiting CXCL2.
Yu X, Feng G, Nian R, Han S, Ke M, Wang L, Li W, Tian S, Lu H
Journal of Cancer 2023;14(18):3444-3456
Journal of Cancer 2023;14(18):3444-3456
HECW2 promotes the progression and chemoresistance of colorectal cancer via AKT/mTOR signaling activation by mediating the ubiquitin-proteasome degradation of lamin B1.
Li F, Wang L, Wang Y, Shen H, Kou Q, Shen C, Xu X, Zhang Y, Zhang J
Journal of Cancer 2023;14(15):2820-2832
Journal of Cancer 2023;14(15):2820-2832
Reduced FANCE Confers Genomic Instability and Malignant Behavior by Regulating Cell Cycle Progression in Endometrial Cancer.
Zheng C, Ren Z, Chen H, Yuan X, Suye S, Yin H, Fu C
Journal of Cancer 2023;14(14):2670-2685
Journal of Cancer 2023;14(14):2670-2685
Significance of NotchScore and JAG1 in predicting prognosis and immune response of low-grade glioma.
Shi B, Ge F, Cai L, Yang Y, Guo X, Wu R, Fan Z, Cao B, Wang N, Si Y, Lin X, Dong W, Sun H
Frontiers in immunology 2023;14:1247288
Frontiers in immunology 2023;14:1247288
Adjuvant therapy with Huatan Sanjie Granules improves the prognosis of patients with primary liver cancer: a cohort study and the investigation of its mechanism of action based on network pharmacology.
Yuan J, Abdurahman A, Cui N, Hao T, Zou J, Liu L, Wu Y
Frontiers in pharmacology 2023;14:1091177
Frontiers in pharmacology 2023;14:1091177
Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study.
Li Y, Yang X, Wang F, Zhao J, Zhang C, Wu D, Yang B, Gao R, Zhao P, Zan Y, Su M, He Z, Liu Y, Wang J, Tang D
Frontiers in pharmacology 2023;14:1076815
Frontiers in pharmacology 2023;14:1076815
Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI.
Li B, Xia Y, Mei S, Ye Z, Song B, Yan X, Lin F, Rao T, Yu W, Mei C, Lv J, Wu M, Mao Z, Zhou X, Cheng F
Theranostics 2023;13(6):1860-1875
Theranostics 2023;13(6):1860-1875
PFDN2 promotes cell cycle progression via the hnRNPD-MYBL2 axis in gastric cancer.
He Q, Ding Z, Chen T, Wu H, Song J, Xiang Z, Yang C, Wang S, Xiong B
Frontiers in oncology 2023;13:1164070
Frontiers in oncology 2023;13:1164070
A Novel Gene Pair CSTF2/DPE2A Impacts Prognosis and Cell Cycle of Hepatocellular Carcinoma.
Huang Y, Xu J, Xie C, Liao Y, Lin R, Zeng Y, Yu F
Journal of hepatocellular carcinoma 2023;10:1639-1657
Journal of hepatocellular carcinoma 2023;10:1639-1657
Knockdown of NF-κB activating protein promotes pancreatic cancer growth and metastasis through mTOR signaling pathway.
Xu X, Hou D, Wang Y, Zhang J, Hei Y, Wang B, Tian S, Zhang Y, Wang F
Molecular biology reports 2023 Sep;50(9):7501-7513
Molecular biology reports 2023 Sep;50(9):7501-7513
Royal jelly acid suppresses hepatocellular carcinoma tumorigenicity by inhibiting H3 histone lactylation at H3K9la and H3K14la sites.
Xu H, Li L, Wang S, Wang Z, Qu L, Wang C, Xu K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154940
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154940
Large HBV Surface Protein-Induced Unfolded Protein Response Dynamically Regulates p27 Degradation in Hepatocellular Carcinoma Progression.
Guo Y, Shao J, Zhang R, Han M, Kong L, Liu Z, Li H, Wei D, Lu M, Zhang S, Zhang C, Wei H, Chen Z, Bian H
International journal of molecular sciences 2023 Sep 7;24(18)
International journal of molecular sciences 2023 Sep 7;24(18)
SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3β signaling pathway through P53.
Zou F, Chen W, Song T, Xing J, Zhang Y, Chen K, Hu W, Li L, Ning J, Li C, Yu W, Cheng F
Cancer cell international 2023 Sep 28;23(1):221
Cancer cell international 2023 Sep 28;23(1):221
Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression.
Liu T, Fan MQ, Xie XX, Shu QP, Du XH, Qi LZ, Zhang XD, Zhang MH, Shan G, Du RL, Li SZ
Journal of translational medicine 2023 Sep 22;21(1):656
Journal of translational medicine 2023 Sep 22;21(1):656
PAQR5 inhibits the growth and metastasis of clear cell renal cell carcinoma by suppressing the JAK/STAT3 signaling pathway.
Wang L, Yue Y, Zhang L, Jing M, Ma M, Liu C, Li Y, Xu S, Wang K, Wang X, Fan J, Zhang M
Cellular oncology (Dordrecht, Netherlands) 2023 Oct;46(5):1317-1332
Cellular oncology (Dordrecht, Netherlands) 2023 Oct;46(5):1317-1332
Brexpiprazole suppresses cell proliferation and de novo lipogenesis through AMPK/SREBP1 pathway in colorectal cancer.
Li T, Liu X, Long X, Li Y, Xiang J, Lv Y, Zhao X, Shi S, Chen W
Environmental toxicology 2023 Oct;38(10):2352-2360
Environmental toxicology 2023 Oct;38(10):2352-2360
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
Fan R, Wang S, Wu Y, Feng Y, Gao M, Cao Y, Ma X, Xie S, Wang C, Gao L, Wang Y, Dai F
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
Aquaporin-7 Facilitates Proliferation and Adipogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Regulating Hydrogen Peroxide Transport.
Ma Y, Zhang J, Li Y, Hu H, Ye Q, Yang C, Yang L, Zhang B, Ma T
Stem cell reviews and reports 2023 Oct;19(7):2378-2390
Stem cell reviews and reports 2023 Oct;19(7):2378-2390
Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via a nuclear receptor (Nur77)-mediated epigenetic regulation of glutaminase 1.
Chen L, Liang B, Xia S, Wang F, Li Z, Shao J, Zhang Z, Chen A, Zheng S, Zhang F
British journal of pharmacology 2023 Oct;180(19):2577-2598
British journal of pharmacology 2023 Oct;180(19):2577-2598
Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase I.
Zhang M, Zhu LZ, Yang CJ, Yan JX, Wang ZP, Bai YP, Peng LZ, Luo HB, Zhang ZJ, Li L, Xu CR, Liu YQ
Bioorganic chemistry 2023 Oct;139:106652
Bioorganic chemistry 2023 Oct;139:106652
LGR4 promotes tumorigenesis by activating TGF-β1/Smad signaling pathway in multiple myeloma.
Yi Z, Ma T, Liu J, Tie W, Li Y, Bai J, Li L, Zhang L
Cellular signalling 2023 Oct;110:110814
Cellular signalling 2023 Oct;110:110814
Mechanism of the HIF-1α/VEGF/VEGFR-2 pathway in the proliferation and apoptosis of human haemangioma endothelial cells.
Zhang W, Sun L, Gao H, Wang S
International journal of experimental pathology 2023 Oct;104(5):258-268
International journal of experimental pathology 2023 Oct;104(5):258-268
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Wang H, Cui X, Wang L, Fan N, Yu M, Qin H, Liu S, Yan Q
Cell death & disease 2023 Oct 6;14(10):651
Cell death & disease 2023 Oct 6;14(10):651
Network pharmacology integrated with experimental validation revealed potential molecular mechanisms of Camellia nitidissima C. W. Chi in the treatment of lung cancer.
Zhou A, Zhou C, Wang D, Qian M, Huang L
Journal of ethnopharmacology 2023 Oct 5;314:116576
Journal of ethnopharmacology 2023 Oct 5;314:116576
Elucidating the pharmacological effects of Compound Kushen injection on MYC-P15-CCND1 signaling pathway in nasopharyngeal carcinoma - An in vitro study.
Wu Z, Wu C, Shi J, Huang Z, Lu S, Tan Y, You R, Hai L, Huang J, Guo S, Gao Y, Jin Z, Tao X, You L, Wu J
Journal of ethnopharmacology 2023 Oct 28;315:116702
Journal of ethnopharmacology 2023 Oct 28;315:116702
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.
Luo H, Huang K, Cheng M, Long X, Zhu X, Wu M
Aging 2023 Oct 17;15(20):11052-11066
Aging 2023 Oct 17;15(20):11052-11066
Inhibition of autophagy can promote the apoptosis of bladder cancer cells induced by SC66 through the endoplasmic reticulum stress pathway.
Wang L, Song R, Ma M, Chen Y, Jiang Y, Li J, Yang Z, Zhang L, Jing M, Wang X, Zhang M, Fan J
Chemico-biological interactions 2023 Oct 1;384:110725
Chemico-biological interactions 2023 Oct 1;384:110725
3-Acetyldeoxynivalenol induces apoptosis, barrier dysfunction and endoplasmic reticulum stress by inhibiting mTORC1-dependent autophagy in porcine enterocytes.
Zhang T, Bai J, Chen G, Chen Z, Zeng S, Yang Y, Wu Z
Chemico-biological interactions 2023 Oct 1;384:110695
Chemico-biological interactions 2023 Oct 1;384:110695
Comprehensive analysis of HOXC8 associated with tumor microenvironment characteristics in colorectal cancer.
Wu S, Zhu D, Feng H, Li Y, Zhou J, Li Y, Hou T
Heliyon 2023 Nov;9(11):e21346
Heliyon 2023 Nov;9(11):e21346
Diallyl trisulfide inhibits gastric cancer stem cell properties through ΔNp63/sonic hedgehog pathway.
Ge M, Zhu J, Yi K, Chen Y, Cao W, Wang M, Xie C, Li X, Geng S, Wu J, Zhong C, Cao H, Jiang Z, Han H
Molecular carcinogenesis 2023 Nov;62(11):1673-1685
Molecular carcinogenesis 2023 Nov;62(11):1673-1685
Methylation of lncSHGL promotes adipocyte differentiation by regulating miR-149/Mospd3 axis.
Huang X, Liu X, Lin J
Cell cycle (Georgetown, Tex.) 2023 Nov;22(21-22):2361-2380
Cell cycle (Georgetown, Tex.) 2023 Nov;22(21-22):2361-2380
NAP1L5 facilitates pancreatic ductal adenocarcinoma progression via TRIM29-mediated ubiquitination of PHLPP1.
Xiao B, Ge Y, Zhao R, Zhang Y, Guo Y, Zhang S, Li B, Qiu P, Chao Z, Zuo S
Biochemical pharmacology 2023 Nov;217:115811
Biochemical pharmacology 2023 Nov;217:115811
A novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation.
An B, Nie W, Hu J, Fan Y, Nie H, Wang M, Zhao Y, Yao H, Ren Y, Zhang C, Wei M, Li W, Liu J, Yang C, Zhang Y, Li X, Tian G
Cell death & disease 2023 Nov 9;14(11):728
Cell death & disease 2023 Nov 9;14(11):728
INHBA gene silencing inhibits proliferation, migration, and invasion of osteosarcoma cells by repressing TGF-β signaling pathway activation.
Zhang H, Huang Y, Wen Q, Li Y, Guo L, Ge N
Journal of orthopaedic surgery and research 2023 Nov 8;18(1):848
Journal of orthopaedic surgery and research 2023 Nov 8;18(1):848
HDAC1-Mediated lncRNA Stimulatory Factor of Follicular Development to Inhibit the Apoptosis of Granulosa Cells and Regulate Sexual Maturity through miR-202-3p-COX1 Axis.
Zhou X, He Y, Quan H, Pan X, Zhou Y, Zhang Z, Yuan X, Li J
Cells 2023 Nov 29;12(23)
Cells 2023 Nov 29;12(23)
Circular RNA ZBTB46 depletion alleviates the progression of Atherosclerosis by regulating the ubiquitination and degradation of hnRNPA2B1 via the AKT/mTOR pathway.
Fu Y, Jia Q, Ren M, Bie H, Zhang X, Zhang Q, He S, Li C, Zhou H, Wang Y, Gan X, Tao Z, Chen X, Jia E
Immunity & ageing : I & A 2023 Nov 21;20(1):66
Immunity & ageing : I & A 2023 Nov 21;20(1):66
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Cheng Z, Wang H, Yang Z, Li J, Chen X
BMC cancer 2023 Nov 20;23(1):1128
BMC cancer 2023 Nov 20;23(1):1128
Upregulated TC1 and downregulated Chibby were correlated with the aberrant β-catenin expression in laryngeal squamous cell carcinoma.
Ren G, Ma B, Wang J, Xu J, Zhang X, Yin C
Medicine 2023 Nov 17;102(46):e36066
Medicine 2023 Nov 17;102(46):e36066
Angelicin inhibits cell growth and promotes apoptosis in oral squamous cell carcinoma by negatively regulating DUSP6/cMYC signaling pathway.
Liu N, Li C, Shang Q, Qi J, Li Q, Deng J, Dan H, Xie L, Chen Q
Experimental cell research 2023 Nov 15;432(2):113793
Experimental cell research 2023 Nov 15;432(2):113793
Exploring the effect and mechanism of Haizao Yuhu decoction containing three variants of glycyrrhiza on goiter using an integrated strategy of network pharmacology and RNA sequencing.
Li M, Xiu L, Liao W, Ren Y, Huo M, Liu H, Chen S, Li N, Gao Y, Yu X, Fan A, Zhong G
Journal of ethnopharmacology 2023 Nov 15;316:116750
Journal of ethnopharmacology 2023 Nov 15;316:116750
Circular RNA transcriptome across multiple tissues reveal skeletal muscle-specific circPSME4 regulating myogenesis.
Zeng M, Yan S, Yang P, Li Q, Li J, Fan X, Liu X, Yao Y, Wang W, Chen R, Han G, Yang Y, Tang Z
International journal of biological macromolecules 2023 Nov 1;251:126322
International journal of biological macromolecules 2023 Nov 1;251:126322
miR-27a-3p relieves heat stress-induced mitochondrial damage and aberrant milk protein synthesis through MEK/ERK pathway in BMECs.
Wang Y, Wu J, Xia SW, Zhao F, Ding Q, Ye XM, Zhong JF, Chen KL, Wang HL
Cell stress & chaperones 2023 May;28(3):265-274
Cell stress & chaperones 2023 May;28(3):265-274
YWHAB knockdown inhibits cell proliferation whilst promoting cell cycle arrest and apoptosis in colon cancer cells through PIK3R2.
Zhou X, Chen A, Zhang T
Experimental and therapeutic medicine 2023 May;25(5):193
Experimental and therapeutic medicine 2023 May;25(5):193
Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
Wu M, Song D, Li H, Ahmad N, Xu H, Yang X, Wang Q, Cheng X, Deng S, Shu X
International journal of molecular sciences 2023 May 29;24(11)
International journal of molecular sciences 2023 May 29;24(11)
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
Jin Y, Zhao L, Wang S, Zhang X, Quan J, Lin Z, Piao J
Carcinogenesis 2023 May 26;44(2):129-142
Carcinogenesis 2023 May 26;44(2):129-142
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Jiang Z, Zhang A, Wei W, Li S
Scientific reports 2023 May 24;13(1):8389
Scientific reports 2023 May 24;13(1):8389
Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42.
Wang X, Zhang X, Sun J, Sun Y, Zhang Y, He L, Wang P, Li F, Sun C
Toxicology and applied pharmacology 2023 May 15;467:116492
Toxicology and applied pharmacology 2023 May 15;467:116492
Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition.
Yang J, Li G, Huang Y, Liu Y
Toxicology and applied pharmacology 2023 May 1;466:116458
Toxicology and applied pharmacology 2023 May 1;466:116458
Knockdown of FGFR3 inhibits the proliferation, migration and invasion of intrahepatic cholangiocarcinoma.
Chen YH, Yang SH, Liu LX, Hu S, Wang XJ, Liao ZJ, Huan YF, He K, Zhang XW
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Mar;55(3):400-406
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Mar;55(3):400-406
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
Wu T, Zhu D, Wu X, Zhang N, Zhang Q
Oncology letters 2023 Mar;25(3):119
Oncology letters 2023 Mar;25(3):119
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
Chen Y, Yang P, Wang J, Gao S, Xiao S, Zhang W, Zhu M, Wang Y, Ke X, Jing H
Experimental hematology & oncology 2023 Mar 7;12(1):28
Experimental hematology & oncology 2023 Mar 7;12(1):28
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
Chen J, Lei C, Zhang H, Huang X, Yang Y, Liu J, Jia Y, Shi H, Zhang Y, Zhang J, Du J
BMC molecular and cell biology 2023 Mar 3;24(1):7
BMC molecular and cell biology 2023 Mar 3;24(1):7
The effects of the prognostic biomarker SAAL1 on cancer growth and its association with the immune microenvironment in lung adenocarcinoma.
Tong S, Jiang N, Wan JH, Chen CR, Wang SH, Wu CY, Guo Q, Xiao XY, Huang H, Zhou T
BMC cancer 2023 Mar 27;23(1):275
BMC cancer 2023 Mar 27;23(1):275
Vacuolar protein sorting 35 (VPS35) acts as a tumor promoter via facilitating cell cycle progression in pancreatic ductal adenocarcinoma.
Gai Y, Qian L, Jiang S, Li J, Zhang X, Yang X, Pan H, Liao Y, Wang H, Huang S, Zhang S, Nie H, Ma M, Li H
Functional & integrative genomics 2023 Mar 18;23(2):90
Functional & integrative genomics 2023 Mar 18;23(2):90
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress.
Wang X, Su Y, Cai Z, Xu Y, Wu X, Al Rudaisat M, Hua C, Chen S, Lai L, Cheng H, Song Y, Zhou Q
Life sciences 2023 Mar 15;317:121439
Life sciences 2023 Mar 15;317:121439
The location of estrogen receptor variant ER-α36 is associated with the invasion of glioblastoma.
Li H, Ge N, Guan X, Han C, Li Y, Shen L, Chen M, Zhang B, Qu C, Zou W
Steroids 2023 Jun;194:109224
Steroids 2023 Jun;194:109224
A study of the role of multiple layer-by-layer assembled bionic extracellular matrix in promoting wound healing via activation of the Wnt signaling pathway.
Wang Z, Cao K, Yan D, Ge Y, Li R, Liu Y, Ma T, Sun X
Journal of biomedical materials research. Part B, Applied biomaterials 2023 Jun;111(6):1159-1170
Journal of biomedical materials research. Part B, Applied biomaterials 2023 Jun;111(6):1159-1170
MTAP-ANRIL gene fusion promotes melanoma epithelial-mesenchymal transition-like process by activating the JNK and p38 signaling pathways.
Lin Z, Lei Y, Wen M, He Q, Tian D, Xie H
Scientific reports 2023 Jun 5;13(1):9073
Scientific reports 2023 Jun 5;13(1):9073
Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma.
Jiang L, Liu Y, Pan Y, Tan Z, Wang J, Zheng G, Qian C, Xu S, Zhu X, Ma W, Guerrini S, Infante-Cossio P, Wu J, Ge M, Cai X
Gland surgery 2023 Jun 30;12(6):834-852
Gland surgery 2023 Jun 30;12(6):834-852
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Liang C, Yi K, Zhou X, Li X, Zhong C, Cao H, Xie C, Zhu J
Phytotherapy research : PTR 2023 Jul;37(7):2995-3008
Phytotherapy research : PTR 2023 Jul;37(7):2995-3008
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
Wu H, Li A, Zheng Q, Gu J, Zhou W
Cancer cell international 2023 Jul 4;23(1):130
Cancer cell international 2023 Jul 4;23(1):130
NVS-ZP7-4 inhibits hepatocellular carcinoma tumorigenesis and promotes apoptosis via PI3K/AKT signaling.
Tong Q, Yan D, Cao Y, Dong X, Abula Y, Yang H, Kong P, Yi M
Scientific reports 2023 Jul 21;13(1):11795
Scientific reports 2023 Jul 21;13(1):11795
Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription.
Zhang J, Meng X, Zhou Y, Jiang Z, Chen H, Meng Z, Zhang Q, Chen W
Cancer cell international 2023 Jul 19;23(1):142
Cancer cell international 2023 Jul 19;23(1):142
NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.
Guo J, Ke S, Chen Q, Zhou J, Guo J, Qiu T
International journal of molecular sciences 2023 Jul 18;24(14)
International journal of molecular sciences 2023 Jul 18;24(14)
Biochemical and clinical effects of RPS20 expression in renal clear cell carcinoma.
Shen C, Chen Z, Zhang Y, Xu W, Peng R, Jiang J, Zuo W, Fan Y, Zheng B
Oncology reports 2023 Jan;49(1)
Oncology reports 2023 Jan;49(1)
MicroRNA-1205 Suppresses Hepatocellular Carcinoma Cell Proliferation via a CSNK2B/CDK4 Axis.
Li X, Xie S, Xia Q, Yan J, Chen S, Shen J
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338221150544
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338221150544
USP39 stabilizes β-catenin by deubiquitination and suppressing E3 ligase TRIM26 pre-mRNA maturation to promote HCC progression.
Wang W, Lei Y, Zhang G, Li X, Yuan J, Li T, Zhong W, Zhang Y, Tan X, Song G
Cell death & disease 2023 Jan 27;14(1):63
Cell death & disease 2023 Jan 27;14(1):63
DNMT1-mediated lncRNA IFFD controls the follicular development via targeting GLI1 by sponging miR-370.
Zhou X, He Y, Pan X, Quan H, He B, Li Y, Bai G, Li N, Zhang Z, Zhang H, Li J, Yuan X
Cell death and differentiation 2023 Feb;30(2):576-588
Cell death and differentiation 2023 Feb;30(2):576-588
Exploration the role of INHBA in Hu sheep granulosa cells using RNA-Seq.
Bao Y, Li X, El-Samahy MA, Yang H, Wang Z, Yang F, Yao X, Wang F
Theriogenology 2023 Feb;197:198-208
Theriogenology 2023 Feb;197:198-208
Astaxanthin Promotes the Survival of Adipose-Derived Stem Cells by Alleviating Oxidative Stress via Activating the Nrf2 Signaling Pathway.
Yang CS, Guo XS, Yue YY, Wang Y, Jin XL
International journal of molecular sciences 2023 Feb 14;24(4)
International journal of molecular sciences 2023 Feb 14;24(4)
Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK.
He Y, Luo M, Lei S, Zeng Z, Chen T, Wu Y, Wang D, Wang L, Wang L
Molecules (Basel, Switzerland) 2023 Feb 12;28(4)
Molecules (Basel, Switzerland) 2023 Feb 12;28(4)
AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway.
Li X, Dong H, Zheng Y, Ding S, Li Y, Li H, Huang H, Zhong C, Xie T, Xu Y
Molecular and cellular probes 2023 Dec;72:101939
Molecular and cellular probes 2023 Dec;72:101939
Chidamide Induces Epstein-Barr Virus (EBV) Lytic Infection and Acts Synergistically with Tenofovir to Eliminate EBV-Positive Burkitt Lymphoma.
Xu L, Zhang M, Tu D, Lu Z, Lu T, Ma D, Zhou Y, Zhang S, Ma Y, Yan D, Wang X, Sang W
The Journal of pharmacology and experimental therapeutics 2023 Dec;387(3):288-298
The Journal of pharmacology and experimental therapeutics 2023 Dec;387(3):288-298
GTF2E2 downregulated by miR-340-5p inhibits the malignant progression of glioblastoma.
Qiao X, Chen Y, Wang Z, Peng N, Niu W, Hou S, Wu J, Ji Y, Niu C, Cheng C
Cancer gene therapy 2023 Dec;30(12):1702-1714
Cancer gene therapy 2023 Dec;30(12):1702-1714
Glucose-responsive, antioxidative HA-PBA-FA/EN106 hydrogel enhanced diabetic wound healing through modulation of FEM1b-FNIP1 axis and promoting angiogenesis.
Zhang W, Zha K, Xiong Y, Hu W, Chen L, Lin Z, Yu C, Zhou W, Cao F, Hu H, Mi B, Liu G
Bioactive materials 2023 Dec;30:29-45
Bioactive materials 2023 Dec;30:29-45
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
Wang T, Zhou Y, Bao H, Liu B, Wang M, Wang L, Pan T
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
CircRNA0007766 accelerates cancer progression via miR-34c-5p/cyclin D1 axis in adenocarcinoma of the esophagogastric junction (AEG).
Wu F, Guo X, Ren Y, Peng Y, Lai Z, Xu J
Cellular signalling 2023 Dec;112:110912
Cellular signalling 2023 Dec;112:110912
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Cui L, Lu Y, Zheng J, Guo B, Zhao X
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Lnc-PKNOX1-1 inhibits tumor progression in cutaneous malignant melanoma by regulating NF-κB/IL-8 axis.
Hong A, Cao M, Li D, Wang Y, Zhang G, Fang F, Zhao L, Wang Q, Lin T, Wang Y
Carcinogenesis 2023 Dec 30;44(12):871-883
Carcinogenesis 2023 Dec 30;44(12):871-883
Fucoxanthin diminishes oxidative stress damage in human placenta-derived mesenchymal stem cells through the PI3K/Akt/Nrf-2 pathway.
Suwanmanee G, Tantrawatpan C, Kheolamai P, Paraoan L, Manochantr S
Scientific reports 2023 Dec 27;13(1):22974
Scientific reports 2023 Dec 27;13(1):22974
GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase.
Huang J, Xie Y, Chen B, Xia Y, Jiang Y, Sun Z, Liu Y
European journal of pharmacology 2023 Dec 15;961:176123
European journal of pharmacology 2023 Dec 15;961:176123
Molecular mechanism and therapeutic potential of HDAC9 in intervertebral disc degeneration.
Lei M, Lin H, Shi D, Hong P, Song H, Herman B, Liao Z, Yang C
Cellular & molecular biology letters 2023 Dec 13;28(1):104
Cellular & molecular biology letters 2023 Dec 13;28(1):104
Artesunate and cisplatin synergistically inhibit HNSCC cell growth and promote apoptosis with artesunate‑induced decreases in Rb and phosphorylated Rb levels.
Okamoto H, Yoshikawa K, Shimada A, Sano R, Inukai D, Yamanaka S, Suzuki S, Ueda R, Ueda H, Fujimoto Y, Ogawa T
Oncology reports 2023 Aug;50(2)
Oncology reports 2023 Aug;50(2)
The MAD2B-APC/C-MDM2 axis mediates acute kidney injury by modulating p53.
Hao Z, Yuan Q, Tang H, Lei C, Chen Y, Su H, Zhang C
The FEBS journal 2023 Aug;290(15):3858-3876
The FEBS journal 2023 Aug;290(15):3858-3876
miR-101-5p overexpression suppresses the proliferation of goat spermatogonial stem cells by targeting EZH2.
Cai Y, Liu Z, Zhang G, Yang Y, Zhang Y, Wang F, Deng M
Animal reproduction science 2023 Aug;255:107281
Animal reproduction science 2023 Aug;255:107281
221S-1a inhibits endothelial proliferation in pathological angiogenesis through ERK/c-Myc signaling.
Yao X, Xue Y, Ma Q, Bai Y, Jia P, Zhang Y, Lai B, He S, Ma Q, Zhang J, Tian H, Yin Q, Zheng X, Zheng X
European journal of pharmacology 2023 Aug 5;952:175805
European journal of pharmacology 2023 Aug 5;952:175805
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Cheng M, Cao H, Yao P, Guan J, Wu P, Ji H, Jiang S, Yuan Y, Fu L, Zheng Q, Li Q
Cell death & disease 2023 Aug 25;14(8):558
Cell death & disease 2023 Aug 25;14(8):558
HHEX suppresses advanced thyroid cancer by interacting with TLE3.
Xu Z, Feng Y, Yan Y, Jin H, Chen Y, Han Y, Huang S, Feng F, Fu H, Yin Y, Huang Y, Wang H, Cheng W
Molecular and cellular endocrinology 2023 Aug 20;574:111988
Molecular and cellular endocrinology 2023 Aug 20;574:111988
WITHDRAWN: Expression of Tmem41b and MMP13 associated with poor outcome in osteosarcomas.
Li GH, Liu X, Feng LJ, Zhang L
Neoplasma 2023 Aug 20;
Neoplasma 2023 Aug 20;
MFAP2 promotes the progression of oral squamous cell carcinoma by activating the Wnt/β-catenin signaling pathway through autophagy.
Zhang H, Shen S, Feng C, Chen G, Wang X
Acta biochimica et biophysica Sinica 2023 Aug 17;55(9):1445-1455
Acta biochimica et biophysica Sinica 2023 Aug 17;55(9):1445-1455
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Jia Y, Huang X, Shi H, Wang M, Chen J, Zhang H, Hou D, Jing H, Du J, Han H, Zhang J
Experimental cell research 2023 Aug 15;429(2):113629
Experimental cell research 2023 Aug 15;429(2):113629
Inhibition of hyaluronic acid degradation pathway suppresses glioma progression by inducing apoptosis and cell cycle arrest.
Yan T, Yang H, Xu C, Liu J, Meng Y, Jiang Q, Li J, Kang G, Zhou L, Xiao S, Xue Y, Xu J, Chen X, Che F
Cancer cell international 2023 Aug 11;23(1):163
Cancer cell international 2023 Aug 11;23(1):163
NUCKS1 promotes the progression of colorectal cancer via activating PI3K/AKT/mTOR signaling pathway.
Zhu LL, Shi JJ, Guo YD, Yang C, Wang RL, Li SS, Gan DX, Ma PX, Li JQ, Su HC
Neoplasma 2023 Apr;70(2):272-286
Neoplasma 2023 Apr;70(2):272-286
Atractylenolide III suppresses senescence-associated secretome via inhibiting cGAS/NF-κB pathway in hepatic stellate cells.
Wu H, Wu L, Xiao L, Gu Y, Liu H, Zhang L, Zhang M, Qi L
Clinical and experimental pharmacology & physiology 2023 Apr;50(4):316-324
Clinical and experimental pharmacology & physiology 2023 Apr;50(4):316-324
CircHGS enhances the progression of bladder cancer by regulating the miR-513a-5p/VEGFC axis and activating the AKT/mTOR signaling pathway.
Zhu Y, Zuo L, Xiong H, Li S, Chen R, Liu H
Cell cycle (Georgetown, Tex.) 2023 Apr;22(8):919-938
Cell cycle (Georgetown, Tex.) 2023 Apr;22(8):919-938
Exosome miR-3184-5p inhibits gastric cancer growth by targeting XBP1 to regulate the AKT, STAT3, and IRE1 signalling pathways.
Lin S, Que Y, Que C, Li F, Deng M, Xu D
Asia-Pacific journal of clinical oncology 2023 Apr;19(2):e27-e38
Asia-Pacific journal of clinical oncology 2023 Apr;19(2):e27-e38
Therapeutic efficacy of a MMAE-based anti-DR5 drug conjugate Oba01 in preclinical models of pancreatic cancer.
Zheng C, Zhou D, Li W, Duan Y, Xu M, Liu J, Cheng J, Xiao Y, Xiao H, Gan T, Liang J, Zheng D, Wang L, Zhang S
Cell death & disease 2023 Apr 29;14(4):295
Cell death & disease 2023 Apr 29;14(4):295
[HSDL2 overexpression promotes rectal cancer progression by regulating cancer cell cycle and promoting cell proliferation].
Cheng Y, He X, Wang L, Xu Y, Shen M, Zhang W, Xia Y, Zhang J, Zhang M, Wang Y, Hu J, Hu J
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Apr 20;43(4):544-551
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Apr 20;43(4):544-551
Berberine promotes IGF2BP3 ubiquitination by TRIM21 to induce G1/S phase arrest in colorectal cancer cells.
Gui Z, Li J, Li J, Li X, Chen L, Ma Z, Tang X, Gong X, Chai X, Lu F, Li M, Ma H, Li X, Ye X
Chemico-biological interactions 2023 Apr 1;374:110408
Chemico-biological interactions 2023 Apr 1;374:110408
Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells.
Sun YS, Wang ZW, Gao Z, Zhao W, Thakur K, Zhong Q, Wei ZJ
Current research in food science 2022;5:904-917
Current research in food science 2022;5:904-917
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
Chen X, Zhang L, Geng J, Chen Z, Cui X
Journal of oncology 2022;2022:8267891
Journal of oncology 2022;2022:8267891
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Shi L, Li Y, Shi M, Li X, Li G, Cen J, Liu D, Wei C, Lin Y
Oxidative medicine and cellular longevity 2022;2022:5142381
Oxidative medicine and cellular longevity 2022;2022:5142381
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
Ma L, Shen T, Peng H, Wu J, Wang W, Gao X
Journal of oncology 2022;2022:2352360
Journal of oncology 2022;2022:2352360
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
Gou W, Luo N, Yu B, Wu H, Wu S, Tian C, Guo J, Ning H, Bi C, Wei H, Hou W, Li Y
International journal of biological sciences 2022;18(6):2639-2651
International journal of biological sciences 2022;18(6):2639-2651
Aldolase A promotes cell proliferation and cisplatin resistance via the EGFR pathway in gastric cancer.
Gu M, Jiang B, Li H, Zhu D, Jiang Y, Xu W
American journal of translational research 2022;14(9):6586-6595
American journal of translational research 2022;14(9):6586-6595
CSTF2 Acts as a Prognostic Marker Correlated with Immune Infiltration in Hepatocellular Carcinoma.
Zhang W, Wan Y, Zhang Y, Liu Q, Zhu X
Cancer management and research 2022;14:2691-2709
Cancer management and research 2022;14:2691-2709
Analysis of regulating activities of 5'-epiequisetin on proliferation, apoptosis, and migration of prostate cancer cells in vitro and in vivo.
Wang X, Luo X, Gan X, Chen C, Yang Z, Wen J, Fang W, Huang H, Gao C, Zhou X, Feng X, Liu Y
Frontiers in pharmacology 2022;13:920554
Frontiers in pharmacology 2022;13:920554
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.
Deng Y, Li H, Song Y, Cen J, Zhang Y, Sui Y, Cui D, Li TC, Xu Y, Wang CC, Chung PWJ, Tang T
Frontiers in endocrinology 2022;13:781149
Frontiers in endocrinology 2022;13:781149
The SKA3-DUSP2 Axis Promotes Gastric Cancer Tumorigenesis and Epithelial-Mesenchymal Transition by Activating the MAPK/ERK Pathway.
Zhang C, Zhao S, Tan Y, Pan S, An W, Chen Q, Wang X, Xu H
Frontiers in pharmacology 2022;13:777612
Frontiers in pharmacology 2022;13:777612
A novel HCC prognosis predictor PDSS1 affects the cell cycle through the STAT3 signaling pathway in HCC.
Rao Z, Li H, Yao W, Wang Q, Ma B, Xue D, Meng X
Frontiers in oncology 2022;12:927468
Frontiers in oncology 2022;12:927468
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
Wang H, Zhao S, Liu Y, Sun F, Huang X, Wu T
Frontiers in oncology 2022;12:898047
Frontiers in oncology 2022;12:898047
Omentin-1 promoted proliferation and ameliorated inflammation, apoptosis, and degeneration in human nucleus pulposus cells.
Cabral VLF, Wang F, Peng X, Gao J, Zhou Z, Sun R, Bao J, Wu X
Archives of gerontology and geriatrics 2022 Sep-Oct;102:104748
Archives of gerontology and geriatrics 2022 Sep-Oct;102:104748
Inhibition of cannabinoid receptor type 1 sensitizes triple-negative breast cancer cells to ferroptosis via regulating fatty acid metabolism.
Li P, Lin Q, Sun S, Yang N, Xia Y, Cao S, Zhang W, Li Q, Guo H, Zhu M, Wang Y, Zheng Z, Li S
Cell death & disease 2022 Sep 21;13(9):808
Cell death & disease 2022 Sep 21;13(9):808
High expression of eIF4A1 predicts unfavorable prognosis in clear cell renal cell carcinoma.
Zhang LL, Chang W, He SB, Zhang B, Ma G, Shang PF, Yue ZJ
Molecular and cellular probes 2022 Oct;65:101845
Molecular and cellular probes 2022 Oct;65:101845
Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies.
Pan C, Qin H, Jin H, Chen W, Guo H, Han X
Toxicology 2022 Oct;480:153326
Toxicology 2022 Oct;480:153326
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Zhao X, Shu D, Sun W, Si S, Ran W, Guo B, Cui L
Cancer communications (London, England) 2022 Oct;42(10):987-1007
Cancer communications (London, England) 2022 Oct;42(10):987-1007
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
Wen P, Wang H, Li Y, Sui X, Hou Z, Guo X, Xue W, Liu D, Wang Y, Gao J
Cell communication and signaling : CCS 2022 Oct 28;20(1):170
Cell communication and signaling : CCS 2022 Oct 28;20(1):170
CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway.
Zhang X, Tian L, Li Z, Liu R, Yu J, Liu B
Biochemical and biophysical research communications 2022 Oct 20;626:220-228
Biochemical and biophysical research communications 2022 Oct 20;626:220-228
L-arginine stimulates the proliferation of mouse mammary epithelial cells and the development of mammary gland in pubertal mice by activating the GPRC6A/PI3K/AKT/mTOR signalling pathway.
Ge Y, Li F, He Y, Cao Y, Guo W, Hu G, Liu J, Fu S
Journal of animal physiology and animal nutrition 2022 Nov;106(6):1383-1395
Journal of animal physiology and animal nutrition 2022 Nov;106(6):1383-1395
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Chen L, Chen D, Li J, He L, Chen T, Song D, Shan S, Wang J, Lu X, Lu B
Cell death & disease 2022 Nov 28;13(11):1007
Cell death & disease 2022 Nov 28;13(11):1007
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway.
Zhang H, Liu J, Dang Q, Wang X, Chen J, Lin X, Yang N, Du J, Shi H, Liu Y, Han J
BMC molecular and cell biology 2022 Nov 16;23(1):48
BMC molecular and cell biology 2022 Nov 16;23(1):48
Integrative and Comprehensive Pan-Cancer Analysis of Lymphocyte-Specific Protein Tyrosine Kinase in Human Tumors.
Han M, Li Y, Guo Y, Zhu W, Jiang J
International journal of molecular sciences 2022 Nov 13;23(22)
International journal of molecular sciences 2022 Nov 13;23(22)
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.
Zhao R, Ge Y, Gong Y, Li B, Xiao B, Zuo S
Aging 2022 Nov 11;14(22):9000-9019
Aging 2022 Nov 11;14(22):9000-9019
G protein subunit gamma 5 promotes the proliferation, metastasis and glycolysis of breast cancer cells through the Wnt/β-catenin pathway.
Yuan Z, Ren R, Xu Z
Anti-cancer drugs 2022 Nov 1;33(10):1004-1011
Anti-cancer drugs 2022 Nov 1;33(10):1004-1011
MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.
Gong J, Shen Y, Jiang F, Wang Y, Chu L, Sun J, Shen P, Chen M
Oncology letters 2022 May;23(5):148
Oncology letters 2022 May;23(5):148
FL118, acting as a 'molecular glue degrader', binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c-Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy.
Ling X, Wu W, Aljahdali IAM, Liao J, Santha S, Fountzilas C, Boland PM, Li F
Clinical and translational medicine 2022 May;12(5):e881
Clinical and translational medicine 2022 May;12(5):e881
MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion.
Lu Y, Zhang X, Li X, Deng L, Wei C, Yang D, Tan X, Pan W, Pang L
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):82
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):82
Taraxasterol prompted the anti-tumor effect in mice burden hepatocellular carcinoma by regulating T lymphocytes.
Ren F, Zhang Y, Qin Y, Shang J, Wang Y, Wei P, Guo J, Jia H, Zhao T
Cell death discovery 2022 May 16;8(1):264
Cell death discovery 2022 May 16;8(1):264
NCAPH regulates gastric cancer progression through DNA damage response.
Wang Y, Li JQ, Yang ZL, Wang L, Zhang JC, Sun YF, Li ZY, Qin L
Neoplasma 2022 Mar;69(2):283-291
Neoplasma 2022 Mar;69(2):283-291
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Wang F, Luo Y, Zhang L, Younis M, Yuan L
Cancer gene therapy 2022 Mar;29(3-4):292-303
Cancer gene therapy 2022 Mar;29(3-4):292-303
Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury.
Tang W, Guo ZD, Chai WN, Du DL, Yang XM, Cao L, Chen H, Zhou C, Cheng CJ, Sun XC, Huang ZJ, Zhong JJ
Neural regeneration research 2022 Mar;17(3):577-586
Neural regeneration research 2022 Mar;17(3):577-586
Cucurbitacin E Triggers Cellular Senescence in Colon Cancer Cells via Regulating the miR-371b-5p/TFAP4 Signaling Pathway.
Yang P, Lian Q, Fu R, Ding GB, Amin S, Li Z, Li Z
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2936-2947
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2936-2947
Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways.
Pan B, Xia Y, Gao Z, Zhao G, Wang L, Fang S, Liu L, Yan S
Chinese medicine 2022 Mar 9;17(1):36
Chinese medicine 2022 Mar 9;17(1):36
Multifunctional photodynamic/photothermal nano-agents for the treatment of oral leukoplakia.
Lin L, Song C, Wei Z, Zou H, Han S, Cao Z, Zhang X, Zhang G, Ran J, Cai Y, Han W
Journal of nanobiotechnology 2022 Mar 4;20(1):106
Journal of nanobiotechnology 2022 Mar 4;20(1):106
The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.
Wei P, Jiang J, Xiao M, Zeng M, Liu X, Zhao B, Chen F
Experimental cell research 2022 Mar 1;412(1):113009
Experimental cell research 2022 Mar 1;412(1):113009
Depletion of B7-H4 from C3H10 T1/2 Mesenchymal Stem Cells Attenuates their Immunomodulatory Therapy in Experimental Autoimmune Encephalomyelitis Mice.
Li H, Sun S, Yin Z, Cao S, Ji X, Duan X, Gao H, Wang M, Fang Q, Dong W, Zhang X, Gu Y, Xue Q
Neurotoxicity research 2022 Jun;40(3):763-774
Neurotoxicity research 2022 Jun;40(3):763-774
Suppression of the Inhibitory Effect of circ_0036176-Translated Myo9a-208 on Cardiac Fibroblast Proliferation by miR-218-5p.
Guo J, Chen LW, Huang ZQ, Guo JS, Li H, Shan Y, Chen ZR, Yan YM, Zhu JN, Guo HM, Fang XH, Shan ZX
Journal of cardiovascular translational research 2022 Jun;15(3):548-559
Journal of cardiovascular translational research 2022 Jun;15(3):548-559
Damnacanthal isolated from morinda species inhibited ovarian cancer cell proliferation and migration through activating autophagy.
Li R, Li H, Lan J, Yang D, Lin X, Xu H, Han B, Yang M, Su B, Liu F, Jiang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154084
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154084
N-methyl-D-aspartate receptor blockers attenuate bleomycin-induced pulmonary fibrosis by inhibiting endogenous mesenchymal stem cells senescence.
Huang P, Zhou Y, Li XH, Zhang YN, Cheng HP, Fu JF, Liu W, Yue S, Luo ZQ
Annals of translational medicine 2022 Jun;10(11):642
Annals of translational medicine 2022 Jun;10(11):642
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.
Liang JJ, Yu WL, Yang L, Qin KM, Yin YP, Li D, Ni YH, Yan JJ, Zhong YX, Deng ZX, Hong K
European journal of medicinal chemistry 2022 Jun 5;236:114313
European journal of medicinal chemistry 2022 Jun 5;236:114313
Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress.
Hao X, Bu W, Lv G, Xu L, Hou D, Wang J, Liu X, Yang T, Zhang X, Liu Q, Gong Y, Shao C
Oncogene 2022 Jan;41(3):427-443
Oncogene 2022 Jan;41(3):427-443
Role of lncRNA LINC01194 in hepatocellular carcinoma via the miR-655-3p/SMAD family member 5 axis.
Liu Y, Liu J, Cui J, Zhong R, Sun G
Bioengineered 2022 Jan;13(1):1115-1125
Bioengineered 2022 Jan;13(1):1115-1125
Interplay between liver circadian rhythm and regeneration after PHx.
Wei S, Zheng Q, Pan Y, Xu Y, Tang J, Cai X
Genomics 2022 Jan;114(1):1-8
Genomics 2022 Jan;114(1):1-8
ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.
Dong S, Liang S, Cheng Z, Zhang X, Luo L, Li L, Zhang W, Li S, Xu Q, Zhong M, Zhu J, Zhang G, Hu S
Journal of experimental & clinical cancer research : CR 2022 Jan 8;41(1):15
Journal of experimental & clinical cancer research : CR 2022 Jan 8;41(1):15
Anlotinib combined with temozolomide suppresses glioblastoma growth via mediation of JAK2/STAT3 signaling pathway.
Xu P, Wang H, Pan H, Chen J, Deng C
Cancer chemotherapy and pharmacology 2022 Feb;89(2):183-196
Cancer chemotherapy and pharmacology 2022 Feb;89(2):183-196
l-Argine regulates the proliferation, apoptosis and endocrine activity by alleviating oxidative stress in sheep endometrial epithelial cells.
Gao X, Li X, Wang Z, Li K, Liang Y, Yao X, Zhang G, Wang F
Theriogenology 2022 Feb;179:187-196
Theriogenology 2022 Feb;179:187-196
Polygonum cuspidatum inhibits the growth of osteosarcoma cells via impeding Akt/ERK/EGFR signaling pathways.
Zhao J, Pan B, Zhou X, Wu C, Hao F, Zhang J, Liu L
Bioengineered 2022 Feb;13(2):2992-3006
Bioengineered 2022 Feb;13(2):2992-3006
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Chen X, Song QL, Ji R, Wang JY, Li ZH, Guo D, Yin TL, Wang SJ, Yang J
Placenta 2022 Feb;118:20-31
Placenta 2022 Feb;118:20-31
Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment.
Liang JJ, Yu WL, Yang L, Xie BH, Qin KM, Yin YP, Yan JJ, Gong S, Liu TY, Zhou HB, Hong K
European journal of medicinal chemistry 2022 Feb 5;229:114081
European journal of medicinal chemistry 2022 Feb 5;229:114081
Ginsenoside Rh4 Suppressed Metastasis of Lung Adenocarcinoma via Inhibiting JAK2/STAT3 Signaling.
Zhang Y, Ma P, Duan Z, Liu Y, Mi Y, Fan D
International journal of molecular sciences 2022 Feb 11;23(4)
International journal of molecular sciences 2022 Feb 11;23(4)
Blockade of Nuclear β-Catenin Signaling via Direct Targeting of RanBP3 with NU2058 Induces Cell Senescence to Suppress Colorectal Tumorigenesis.
Zheng CC, Liao L, Liu YP, Yang YM, He Y, Zhang GG, Li SJ, Liu T, Xu WW, Li B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(34):e2202528
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(34):e2202528
HMGB1 induces radioresistance through PI3K/AKT/ATM pathway in esophageal squamous cell carcinoma.
Zhang X, Zou N, Deng W, Song C, Yan K, Shen W, Zhu S
Molecular biology reports 2022 Dec;49(12):11933-11945
Molecular biology reports 2022 Dec;49(12):11933-11945
Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma.
Fuller AM, DeVine A, Murazzi I, Mason NJ, Weber K, Eisinger-Mathason TSK
Cellular oncology (Dordrecht, Netherlands) 2022 Dec;45(6):1277-1295
Cellular oncology (Dordrecht, Netherlands) 2022 Dec;45(6):1277-1295
lncRNA NEAT1-let 7b-P21 axis mediates the proliferation of neural stem cells cultured in vitro promoted by radial extracorporeal shock wave.
Han K, Kang N, Yu X, Lu J, Ma Y
Regenerative therapy 2022 Dec;21:139-147
Regenerative therapy 2022 Dec;21:139-147
Tumor-targeted dual-starvation therapy based on redox-responsive micelle nanosystem with co-loaded LND and BPTES.
Fu Z, Du H, Meng S, Yao M, Zhao P, Li X, Zheng X, Yuan Z, Yang H, Cai K, Dai L
Materials today. Bio 2022 Dec;16:100449
Materials today. Bio 2022 Dec;16:100449
Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis.
Varier KM, Dan G, Liu W, Wu G, Xiao C, Lei H, Ling T, Jiang Y, Chen Y, Ben-David Y, Li Y, Zhang N, Gajendran B, Shen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113887
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113887
NORAD promotes multiple myeloma cell progression via BMP6/P-ERK1/2 axis.
Ma T, Chen Y, Yi ZG, Liu J, Li YH, Bai J, Tie WT, Huang M, Zhu XF, Wang J, Du J, Zuo XQ, Li Q, Lin FL, Tang L, Guo J, Xiao HW, Lei Q, Ma XL, Li LJ, Zhang LS
Cellular signalling 2022 Dec;100:110474
Cellular signalling 2022 Dec;100:110474
Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats.
Hao J, Xi Y, Jiao L, Wen X, Wu R, Chang G, Sun F, Wei C, Li H
Cellular signalling 2022 Dec;100:110465
Cellular signalling 2022 Dec;100:110465
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Wu X, Zhang H, Jiang G, Peng M, Li C, Lu J, Jiang S, Yang X, Jiang Y
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis.
Chen CC, Xie XM, Zhao XK, Zuo S, Li HY
Journal of clinical and translational hepatology 2022 Dec 28;10(6):1125-1137
Journal of clinical and translational hepatology 2022 Dec 28;10(6):1125-1137
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Yang W, Guo C, Herman JG, Zhu C, Lv H, Su X, Zhang L, Zhang M, Guo M
Clinical epigenetics 2022 Dec 2;14(1):164
Clinical epigenetics 2022 Dec 2;14(1):164
FANCD2 promotes the malignant behavior of endometrial cancer cells and its prognostic value.
Zheng C, Ren Z, Chen H, Yuan X, Suye S, Yin H, Zhou Z, Fu C
Experimental cell research 2022 Dec 15;421(2):113388
Experimental cell research 2022 Dec 15;421(2):113388
Aerobic glycolysis and tumor progression of hepatocellular carcinoma are mediated by ubiquitin of P53 K48-linked regulated by TRIM37.
Ge Y, Zhao R, Li B, Xiao B, Zhou L, Zuo S
Experimental cell research 2022 Dec 15;421(2):113377
Experimental cell research 2022 Dec 15;421(2):113377
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Li H, Liu J, Fan N, Wang H, Thomas AM, Yan Q, Li S, Qin H
Pathology, research and practice 2022 Aug;236:153984
Pathology, research and practice 2022 Aug;236:153984
Long noncoding RNA BMPR1B-AS1 facilitates endometrial cancer cell proliferation and metastasis by sponging miR-7-2-3p to modulate the DCLK1/Akt/NF-κB pathway.
Lai T, Qiu H, Si L, Zhen Y, Chu D, Guo R
Cell cycle (Georgetown, Tex.) 2022 Aug;21(15):1599-1618
Cell cycle (Georgetown, Tex.) 2022 Aug;21(15):1599-1618
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
Deng W, Sun Z, Chen S, Li G, Liu X, Huang L, Zhang Z
Toxicology research 2022 Aug;11(4):605-615
Toxicology research 2022 Aug;11(4):605-615
Alpha-linolenic acid inhibits hepatocellular carcinoma cell growth through Farnesoid X receptor/β-catenin signaling pathway.
Feng S, Xie X, Chen C, Zuo S, Zhao X, Li H
Nutrition & metabolism 2022 Aug 23;19(1):57
Nutrition & metabolism 2022 Aug 23;19(1):57
High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis.
Zhang G, Liu B, Shang H, Wu G, Wu D, Wang L, Li S, Wang Z, Wang S, Yuan J
BMC medical genomics 2022 Aug 15;15(1):180
BMC medical genomics 2022 Aug 15;15(1):180
FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.
Ke S, Liu Z, Wang Q, Zhai G, Shao H, Yu X, Guo J
Cancers 2022 Aug 13;14(16)
Cancers 2022 Aug 13;14(16)
MiR-125b enhances doxorubicin-induced cardiotoxicity by suppressing the nucleus-cytoplasmic translocation of YAP via targeting STARD13.
Jin X, Yu W, Ye P
Environmental toxicology 2022 Apr;37(4):730-740
Environmental toxicology 2022 Apr;37(4):730-740
Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.
Lu H, Yin H, Qu L, Ma X, Fu R, Fan D
Food & function 2022 Apr 4;13(7):3793-3811
Food & function 2022 Apr 4;13(7):3793-3811
Histone methyltransferase KMT2D cooperates with MEF2A to promote the stem-like properties of oral squamous cell carcinoma.
Wang X, Li R, Wu L, Chen Y, Liu S, Zhao H, Wang Y, Wang L, Shao Z
Cell & bioscience 2022 Apr 27;12(1):49
Cell & bioscience 2022 Apr 27;12(1):49
Lactation Activity and Mechanism of Milk-Protein Synthesis by Peptides from Oyster Hydrolysates.
Chen S, Qin X, Zhang C, Cao W, Zheng H, Lin H
Nutrients 2022 Apr 24;14(9)
Nutrients 2022 Apr 24;14(9)
Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling.
Zhao N, Gui X, Fang Q, Zhang R, Zhu W, Zhang H, Li Q, Zhou Y, Zhao J, Cui X, Gao G, Tang H, Shen N, Chen T, Song H, Shen W
Journal of nanobiotechnology 2022 Apr 2;20(1):174
Journal of nanobiotechnology 2022 Apr 2;20(1):174
MicroRNA-146a promotes proliferation, migration, and invasion of HepG2 via regulating FLAP.
Wang H, Zhang S, Li T, Wang L, Lv W, Wang S, Ma D, Zang Y, Zhu X, Xu Y, Zheng L, Shen J, Wei W
Cancer cell international 2022 Apr 11;22(1):149
Cancer cell international 2022 Apr 11;22(1):149
Identification and Validation of HOTAIRM1 as a Novel Biomarker for Oral Squamous Cell Carcinoma.
Yu Y, Niu J, Zhang X, Wang X, Song H, Liu Y, Jiao X, Chen F
Frontiers in bioengineering and biotechnology 2021;9:798584
Frontiers in bioengineering and biotechnology 2021;9:798584
Transmembrane Protein Ttyh1 Maintains the Quiescence of Neural Stem Cells Through Ca(2+)/NFATc3 Signaling.
Cao Y, Wu HN, Cao XL, Yue KY, Han WJ, Cao ZP, Zhang YF, Gao XY, Luo C, Jiang XF, Han H, Zheng MH
Frontiers in cell and developmental biology 2021;9:779373
Frontiers in cell and developmental biology 2021;9:779373
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806
Frontiers in cell and developmental biology 2021;9:679806
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
Ou G, Jiang X, Gao A, Li X, Lin Z, Pei S
Frontiers in veterinary science 2021;8:801407
Frontiers in veterinary science 2021;8:801407
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
Feng F, Zhao Z, Zhou Y, Cheng Y, Wu X, Heng X
Frontiers in molecular biosciences 2021;8:705008
Frontiers in molecular biosciences 2021;8:705008
Sinomenine Suppresses Development of Hepatocellular Carcinoma Cells via Inhibiting MARCH1 and AMPK/STAT3 Signaling Pathway.
Yang W, Feng Q, Li M, Su J, Wang P, Wang X, Yin Y, Wang X, Zhao M
Frontiers in molecular biosciences 2021;8:684262
Frontiers in molecular biosciences 2021;8:684262
Acyl-CoA Thioesterase 7 is Transcriptionally Activated by Krüppel-Like Factor 13 and Promotes the Progression of Hepatocellular Carcinoma.
Xie X, Chen C, Feng S, Zuo S, Zhao X, Li H
Journal of hepatocellular carcinoma 2021;8:1623-1641
Journal of hepatocellular carcinoma 2021;8:1623-1641
Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.
Zhang Y, Chen G, Zhuang X, Guo M
Oxidative medicine and cellular longevity 2021;2021:8807676
Oxidative medicine and cellular longevity 2021;2021:8807676
In Hepatocellular Carcinoma, miRNA-296-3p Targets MSL2 and Suppresses Cell Proliferation and Invasion.
Li X, An M, Gao Z
Journal of oncology 2021;2021:7430468
Journal of oncology 2021;2021:7430468
MRC2 Promotes Proliferation and Inhibits Apoptosis of Diabetic Nephropathy.
Li L, Chen X, Zhang H, Wang M, Lu W
Analytical cellular pathology (Amsterdam) 2021;2021:6619870
Analytical cellular pathology (Amsterdam) 2021;2021:6619870
Effects of MicroRNA-195-5p on Biological Behaviors and Radiosensitivity of Lung Adenocarcinoma Cells via Targeting HOXA10.
Yuan C, Bai R, Gao Y, Jiang X, Li S, Sun W, Li Y, Huang Z, Gong Y, Xie C
Oxidative medicine and cellular longevity 2021;2021:4522210
Oxidative medicine and cellular longevity 2021;2021:4522210
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
Bai R, Yuan C, Sun W, Zhang J, Luo Y, Gao Y, Li Y, Gong Y, Xie C
International journal of biological sciences 2021;17(8):1995-2008
International journal of biological sciences 2021;17(8):1995-2008
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Bai M, Cui M, Li M, Yao X, Wu Y, Zheng L, Sun L, Song Q, Wang S, Liu L, Yu C, Huang Y
International journal of biological sciences 2021;17(13):3493-3507
International journal of biological sciences 2021;17(13):3493-3507
Downregulation of m(6)A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.
Wang J, Tan L, Jia B, Yu X, Yao R, OUYang N, Yu X, Cao X, Tong J, Chen T, Chen R, Li J
International journal of biological sciences 2021;17(10):2633-2651
International journal of biological sciences 2021;17(10):2633-2651
Loss of DAB2IP Contributes to Cell Proliferation and Cisplatin Resistance in Gastric Cancer.
Wang G, Wang X, Han M, Wang X
OncoTargets and therapy 2021;14:979-988
OncoTargets and therapy 2021;14:979-988
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
Chen Z, Zhang Y, Wu X, Zhang J, Xu W, Shen C, Zheng B
OncoTargets and therapy 2021;14:2941-2952
OncoTargets and therapy 2021;14:2941-2952
ACTL6A Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells and Correlates with Poor Clinical Outcomes.
Li RZ, Li YY, Qin H, Li SS
OncoTargets and therapy 2021;14:199-211
OncoTargets and therapy 2021;14:199-211
Network pharmacology-guided mechanism study uncovers inhibitory effect of Mahuang Decoction on lung cancer growth by impeding Akt/ERK signaling pathways.
Pan Y, Chen Y, Wu C, Ai J, Wang Y, Jia J, Liu L
American journal of translational research 2021;13(4):2094-2110
American journal of translational research 2021;13(4):2094-2110
Coronin 6 promotes hepatocellular carcinoma progression by enhancing canonical Wnt/beta-catenin signaling pathway.
Zhang J, Li P, Li T, Zhou Z, Wu H, Zhang L
Journal of Cancer 2021;12(24):7465-7476
Journal of Cancer 2021;12(24):7465-7476
ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2.
Yang HL, Xu C, Yang YK, Tang WQ, Hong M, Pan L, Chen HY
Journal of Cancer 2021;12(24):7266-7276
Journal of Cancer 2021;12(24):7266-7276
Kaempferol Ameliorates the Inhibitory Activity of Dexamethasone in the Osteogenesis of MC3T3-E1 Cells by JNK and p38-MAPK Pathways.
Xie B, Zeng Z, Liao S, Zhou C, Wu L, Xu D
Frontiers in pharmacology 2021;12:739326
Frontiers in pharmacology 2021;12:739326
Exploring the Prognostic Value, Immune Implication and Biological Function of H2AFY Gene in Hepatocellular Carcinoma.
Huang Y, Huang S, Ma L, Wang Y, Wang X, Xiao L, Qin W, Li L, Yuan X
Frontiers in immunology 2021;12:723293
Frontiers in immunology 2021;12:723293
Myricetin Induces Autophagy and Cell Cycle Arrest of HCC by Inhibiting MARCH1-Regulated Stat3 and p38 MAPK Signaling Pathways.
Yang W, Su J, Li M, Li T, Wang X, Zhao M, Hu X
Frontiers in pharmacology 2021;12:709526
Frontiers in pharmacology 2021;12:709526
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Yang M, Li WY, Xie J, Wang ZL, Wen YL, Zhao CC, Tao L, Li LF, Tian Y, Sheng J
Frontiers in pharmacology 2021;12:639256
Frontiers in pharmacology 2021;12:639256
Periplocymarin Induced Colorectal Cancer Cells Apoptosis Via Impairing PI3K/AKT Pathway.
Cheng Y, Wang G, Zhao L, Dai S, Han J, Hu X, Zhou C, Wang F, Ma H, Li B, Meng Z
Frontiers in oncology 2021;11:753598
Frontiers in oncology 2021;11:753598
CDCA7 Facilitates Tumor Progression by Directly Regulating CCNA2 Expression in Esophageal Squamous Cell Carcinoma.
Li H, Weng Y, Wang S, Wang F, Wang Y, Kong P, Zhang L, Cheng C, Cui H, Xu E, Wei S, Guo D, Chen F, Bi Y, Meng Y, Cheng X, Cui Y
Frontiers in oncology 2021;11:734655
Frontiers in oncology 2021;11:734655
Oleic Acid and Insulin as Key Characteristics of T2D Promote Colorectal Cancer Deterioration in Xenograft Mice Revealed by Functional Metabolomics.
Zhang Y, Wang D, Lv B, Hou X, Liu Q, Liao C, Xu R, Zhang Y, Xu F, Zhang P
Frontiers in oncology 2021;11:685059
Frontiers in oncology 2021;11:685059
Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
Zhu X, Li R, Wang C, Zhou S, Fan Y, Ma S, Gao D, Gai N, Yang J
Frontiers in oncology 2021;11:661184
Frontiers in oncology 2021;11:661184
The lncRNA ADAMTS9-AS2 Regulates RPL22 to Modulate TNBC Progression via Controlling the TGF-β Signaling Pathway.
Ni K, Huang Z, Zhu Y, Xue D, Jin Q, Zhang C, Gu C
Frontiers in oncology 2021;11:654472
Frontiers in oncology 2021;11:654472
Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway.
Shi S, Li C, Zhang Y, Deng C, Liu W, Du J, Li Q, Ji Y, Guo L, Liu L, Hu H, Liu Y, Cui H
Frontiers in oncology 2021;11:648052
Frontiers in oncology 2021;11:648052
miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.
Lei S, Zeng Z, He Z, Cao W
Oncology reports 2021 Sep;46(3)
Oncology reports 2021 Sep;46(3)
Paired-like homeodomain transcription factor 2 affects endometrial cell function and embryo implantation through the Wnt/β-catenin pathway.
Zhang H, Qi J, Guo J, Wang Y, Guan Y, Fan J, Sui L, Xu Y, Kong L, Yan B, Kong Y
Cell biology international 2021 Sep;45(9):1957-1965
Cell biology international 2021 Sep;45(9):1957-1965
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.
Meng H, Shen M, Li J, Zhang R, Li X, Zhao L, Huang G, Liu J
European journal of pharmacology 2021 Sep 5;906:174280
European journal of pharmacology 2021 Sep 5;906:174280
PHLDA3 exerts an antitumor function in prostate cancer by down-regulating Wnt/β-catenin pathway via inhibition of Akt.
Ma S, Quan P, Yu C, Fan X, Yang S, Jia W, Zhang L, Wang F, Liu F, Yang L, Qin W, Yang X
Biochemical and biophysical research communications 2021 Sep 24;571:66-73
Biochemical and biophysical research communications 2021 Sep 24;571:66-73
ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway.
Yu S, Wang S, Sun X, Wu Y, Zhao J, Liu J, Yang D, Jiang Y
Oncology letters 2021 Oct;22(4):736
Oncology letters 2021 Oct;22(4):736
Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-AKT signaling pathway as revealed by network pharmacology and in vitro experimental verification.
Wang Y, Chu F, Lin J, Li Y, Johnson N, Zhang J, Gai C, Su Z, Cheng H, Wang L, Ding X
Journal of ethnopharmacology 2021 Oct 28;279:114399
Journal of ethnopharmacology 2021 Oct 28;279:114399
Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities.
Wang S, Zhang RH, Zhang H, Wang YC, Yang D, Zhao YL, Yan GY, Xu GB, Guan HY, Zhou YH, Cui DB, Liu T, Li YJ, Liao SG, Zhou M
European journal of medicinal chemistry 2021 Oct 15;222:113573
European journal of medicinal chemistry 2021 Oct 15;222:113573
TMEM98, a novel secretory protein, promotes endothelial cell adhesion as well as vascular smooth muscle cell proliferation and migration.
Li M, Zhu H, Hu X, Gao F, Hu X, Cui Y, Wei X, Xie C, Lv G, Zhao Y, Gao Y
Canadian journal of physiology and pharmacology 2021 May;99(5):536-548
Canadian journal of physiology and pharmacology 2021 May;99(5):536-548
MiR-3663-3p Inhibits the Progression of Gastric Cancer Through the CCND1 Pathway.
Takao K, Konishi H, Matsubara D, Shoda K, Arita T, Shimizu H, Komatsu S, Shiozaki A, Yamamoto Y, Kubota T, Fujiwara H, Okamoto K, Otsuji E
Anticancer research 2021 May;41(5):2441-2449
Anticancer research 2021 May;41(5):2441-2449
Apatinib regulates the growth of gastric cancer cells by modulating apoptosis and autophagy.
Liu X, Zheng Q, Yu Q, Hu Y, Cheng Y, Shao Z, Chen L, Ding W, Gao D
Naunyn-Schmiedeberg's archives of pharmacology 2021 May;394(5):1009-1018
Naunyn-Schmiedeberg's archives of pharmacology 2021 May;394(5):1009-1018
Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.
Ren M, Xu H, Xia H, Tang Q, Bi F
Cell death discovery 2021 May 29;7(1):125
Cell death discovery 2021 May 29;7(1):125
LINC00857 contributes to proliferation and lymphomagenesis by regulating miR-370-3p/CBX3 axis in diffuse large B-cell lymphoma.
Huang Y, Lin Y, Song X, Wu D
Carcinogenesis 2021 May 28;42(5):733-741
Carcinogenesis 2021 May 28;42(5):733-741
eIF6 promotes the malignant progression of human hepatocellular carcinoma via the mTOR signaling pathway.
Sun L, Liu S, Wang X, Zheng X, Chen Y, Shen H
Journal of translational medicine 2021 May 20;19(1):216
Journal of translational medicine 2021 May 20;19(1):216
LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.
Tao Y, Zhang J, Chen L, Liu X, Yao M, Zhang H
Cell death & disease 2021 May 18;12(6):510
Cell death & disease 2021 May 18;12(6):510
Role of Glycated High Mobility Group Box-1 in Gastric Cancer.
Kishi S, Nishiguchi Y, Honoki K, Mori S, Fujiwara-Tani R, Sasaki T, Fujii K, Kawahara I, Goto K, Nakashima C, Kido A, Tanaka Y, Luo Y, Kuniyasu H
International journal of molecular sciences 2021 May 13;22(10)
International journal of molecular sciences 2021 May 13;22(10)
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
Long Y, Wang Z, Fan J, Yuan L, Tong C, Zhao Y, Liu B
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.
Zhu J, Li X, Liang C, Zhou X, Ge M, Chen Y, Jin J, Yin J, Xu H, Xie C, Zhong C
Cell death discovery 2021 May 12;7(1):102
Cell death discovery 2021 May 12;7(1):102
Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway.
Chen Y, Xu T, Li M, Li C, Ma Y, Chen G, Sun Y, Zheng H, Wu G, Liao W, Liao Y, Chen Y, Bin J
Clinical science (London, England : 1979) 2021 Mar 26;135(6):811-828
Clinical science (London, England : 1979) 2021 Mar 26;135(6):811-828
Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells.
Wu H, Cui M, Li C, Li H, Dai Y, Cui K, Li Z
Journal of agricultural and food chemistry 2021 Mar 17;69(10):3060-3068
Journal of agricultural and food chemistry 2021 Mar 17;69(10):3060-3068
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Zhang Z, Wu H, Huang S, Chen L, Chen X, Zhang W, Liao L, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
DNA methylation mediated RSPO2 to promote follicular development in mammals.
Zhou X, He Y, Li N, Bai G, Pan X, Zhang Z, Zhang H, Li J, Yuan X
Cell death & disease 2021 Jun 26;12(7):653
Cell death & disease 2021 Jun 26;12(7):653
Epidermal stem cells maintain stemness via a biomimetic micro/nanofiber scaffold that promotes wound healing by activating the Notch signaling pathway.
Lin Z, Zhao C, Lei Z, Zhang Y, Huang R, Lin B, Dong Y, Zhang H, Li J, Li X
Stem cell research & therapy 2021 Jun 10;12(1):341
Stem cell research & therapy 2021 Jun 10;12(1):341
Puromycin-sensitive aminopeptidase is required for C2C12 myoblast proliferation and differentiation.
Osana S, Kitajima Y, Suzuki N, Nunomiya A, Takada H, Kubota T, Murayama K, Nagatomi R
Journal of cellular physiology 2021 Jul;236(7):5293-5305
Journal of cellular physiology 2021 Jul;236(7):5293-5305
Tacrolimus inhibits oral carcinogenesis through cell cycle control.
Li Y, Wang Y, Li J, Ling Z, Chen W, Zhang L, Hu Q, Wu T, Cheng B, Wang Y, Xia J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111545
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111545
Methylation of NRN1 is a novel synthetic lethal marker of PI3K-Akt-mTOR and ATR inhibitors in esophageal cancer.
Du W, Gao A, Herman JG, Wang L, Zhang L, Jiao S, Guo M
Cancer science 2021 Jul;112(7):2870-2883
Cancer science 2021 Jul;112(7):2870-2883
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Li P, Cao S, Huang Y, Zhang Y, Liu J, Cai X, Zhou L, Li J, Jiang Z, Ding L, Zheng Z, Li S, Ye Q
Cell death discovery 2021 Jul 29;7(1):198
Cell death discovery 2021 Jul 29;7(1):198
miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.
Xiong X, Xu W, Gong J, Wang L, Dai M, Chen G, Yuan L
Cellular signalling 2021 Jan;77:109818
Cellular signalling 2021 Jan;77:109818
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Jin J, Zhou M, Wang X, Liu M, Huang H, Yan F, Yu Z, Shu X, Huo X, Feng L, Zhang B, Huang S, Deng S, Wang C, Ma X
Fitoterapia 2021 Jan;148:104779
Fitoterapia 2021 Jan;148:104779
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V) 1.5-mediated EMT and FAK/Paxillin signaling pathway.
Liu C, Yu M, Li Y, Wang H, Xu C, Zhang X, Li M, Guo H, Ma D, Guo X
Cancer medicine 2021 Jan;10(1):337-349
Cancer medicine 2021 Jan;10(1):337-349
Long Non-Coding RNA LOC648987 Promotes Proliferation and Metastasis of Renal Cell Carcinoma by Regulating Epithelial-Mesenchymal Transition.
Su Y, Zhou L, Yu Q, Lu J, Liu W
Technology in cancer research & treatment 2021 Jan-Dec;20:1533033821997834
Technology in cancer research & treatment 2021 Jan-Dec;20:1533033821997834
ActivinA activates Notch1-Shh signaling to regulate proliferation in C2C12 skeletal muscle cells.
Ma L, Li C, Lian S, Xu B, Yuan J, Lu J, Yang H, Guo J, Ji H
Molecular and cellular endocrinology 2021 Jan 1;519:111055
Molecular and cellular endocrinology 2021 Jan 1;519:111055
Ezrin Promotes the Proliferation, Migration, and Invasion of Ovarian Cancer Cells.
Li MJ, Xiong D, Huang H, Wen ZY
Biomedical and environmental sciences : BES 2021 Feb 20;34(2):139-151
Biomedical and environmental sciences : BES 2021 Feb 20;34(2):139-151
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Zhang M, Wang L, Yue Y, Zhang L, Liu T, Jing M, Liang X, Ma M, Xu S, Wang K, Wang X, Fan J
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L-formate axis.
Cui L, Zhao X, Jin Z, Wang H, Yang SF, Hu S
Journal of pineal research 2021 Dec;71(4):e12767
Journal of pineal research 2021 Dec;71(4):e12767
MicroRNA-4423-3p inhibits proliferation of fibroblast-like synoviocytes by targeting matrix metalloproteinase 13 in rheumatoid arthritis.
Xu W, Ye L, Wu H
Bioengineered 2021 Dec;12(2):9411-9423
Bioengineered 2021 Dec;12(2):9411-9423
MiR-130a-3p suppresses colorectal cancer growth by targeting Wnt Family Member 1 (WNT1).
Song GL, Xiao M, Wan XY, Deng J, Ling JD, Tian YG, Li M, Yin J, Zheng RY, Tang Y, Liu GY
Bioengineered 2021 Dec;12(1):8407-8418
Bioengineered 2021 Dec;12(1):8407-8418
α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway.
Zhang S, Wang J, Chen T, Wang J, Wang Y, Yu Z, Zhao K, Zheng K, Chen Y, Wang Z, Li B, Wang C, Huang W, Fu Z, Chen J
Bioengineered 2021 Dec;12(1):5688-5704
Bioengineered 2021 Dec;12(1):5688-5704
Roles of WNT6 in Sheep Endometrial Epithelial Cell Cycle Progression and Uterine Glands Organogenesis.
Gao X, Yao X, Li X, Liang Y, Liu Z, Wang Z, Li K, Li Y, Zhang G, Wang F
Veterinary sciences 2021 Dec 9;8(12)
Veterinary sciences 2021 Dec 9;8(12)
CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.
Liao Q, Ren Y, Yang Y, Zhu X, Zhi Y, Zhang Y, Chen Y, Ding Y, Zhao L
Oncogenesis 2021 Dec 3;10(12):84
Oncogenesis 2021 Dec 3;10(12):84
LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma.
He X, Sheng J, Yu W, Wang K, Zhu S, Liu Q
Cellular and molecular neurobiology 2021 Aug;41(6):1271-1284
Cellular and molecular neurobiology 2021 Aug;41(6):1271-1284
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Sun W, Li S, Tang G, Sun S, Luo Y, Bai R, Han L, Jiang X, Gao Y, Huang Z, Zhang J, Gong Y, Xie C
Cancer medicine 2021 Aug;10(15):5256-5269
Cancer medicine 2021 Aug;10(15):5256-5269
Dimethyl fumarate inhibits antibody-induced platelet destruction in immune thrombocytopenia mouse.
Tong H, Ding Y, Gui X, Sun Z, Wang G, Zhang S, Xu Z, Wang X, Xu X, Ju W, Li Y, Li Z, Zeng L, Xu K, Qiao J
Thrombosis journal 2021 Aug 28;19(1):61
Thrombosis journal 2021 Aug 28;19(1):61
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J, Zhong C
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
ESM1 promotes triple-negative breast cancer cell proliferation through activating AKT/NF-κB/Cyclin D1 pathway.
Liu W, Yang Y, He B, Ma F, Sun F, Guo M, Zhang M, Dong Z
Annals of translational medicine 2021 Apr;9(7):533
Annals of translational medicine 2021 Apr;9(7):533
M2 Macrophage-Derived Exosomal miR-590-3p Attenuates DSS-Induced Mucosal Damage and Promotes Epithelial Repair via the LATS1/YAP/ β-Catenin Signalling Axis.
Deng F, Yan J, Lu J, Luo M, Xia P, Liu S, Wang X, Zhi F, Liu D
Journal of Crohn's & colitis 2021 Apr 6;15(4):665-677
Journal of Crohn's & colitis 2021 Apr 6;15(4):665-677
Circular RNA circ_0005774 contributes to proliferation and suppresses apoptosis of acute myeloid leukemia cells via circ_0005774/miR-192-5p/ULK1 ceRNA pathway.
Li Q, Luan Q, Zhu H, Zhao Y, Ji J, Wu F, Yan J
Biochemical and biophysical research communications 2021 Apr 30;551:78-85
Biochemical and biophysical research communications 2021 Apr 30;551:78-85
Ixazomib inhibits myeloma cell proliferation by targeting UBE2K.
Wang Q, Dong Z, Su J, Huang J, Xiao P, Tian L, Chen Y, Ma L, Chen X
Biochemical and biophysical research communications 2021 Apr 16;549:1-7
Biochemical and biophysical research communications 2021 Apr 16;549:1-7
F4/80(+) Kupffer Cell-Derived Oncostatin M Sustains the Progression Phase of Liver Regeneration through Inhibition of TGF-β2 Pathway.
Lu Q, Shen H, Yu H, Fu J, Dong H, Chen Y, Wang H
Molecules (Basel, Switzerland) 2021 Apr 13;26(8)
Molecules (Basel, Switzerland) 2021 Apr 13;26(8)
Helium/Argon-Generated Cold Atmospheric Plasma Facilitates Cutaneous Wound Healing.
Lou BS, Hsieh JH, Chen CM, Hou CW, Wu HY, Chou PY, Lai CH, Lee JW
Frontiers in bioengineering and biotechnology 2020;8:683
Frontiers in bioengineering and biotechnology 2020;8:683
Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer.
Zeng Y, Zou M, Liu Y, Que K, Wang Y, Liu C, Gong J, You Y
Frontiers in medicine 2020;7:572494
Frontiers in medicine 2020;7:572494
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Feng B, Zhao C, Li J, Yu J, Zhang Y, Zhang X, Tian T, Zhao L
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Integrated Bioinformatics Analysis of the Clinical Value and Biological Function of ATAD2 in Hepatocellular Carcinoma.
Meng X, Wang L, Zhu B, Zhang J, Guo S, Li Q, Zhang T, Zheng Z, Wu G, Zhao Y
BioMed research international 2020;2020:8657468
BioMed research international 2020;2020:8657468
UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.
Kuang M, Yang M, Li L, Li C, Wang G
Oxidative medicine and cellular longevity 2020;2020:4045674
Oxidative medicine and cellular longevity 2020;2020:4045674
Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells.
Lin W, Tong C, Zhang W, Cen W, Wang Y, Li J, Zhu Z, Yu J, Lu B
BioMed research international 2020;2020:3235786
BioMed research international 2020;2020:3235786
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
Mao Y, Li W, Hua B, Gu X, Pan W, Chen Q, Xu B, Wang Z, Lu C
BioMed research international 2020;2020:2406159
BioMed research international 2020;2020:2406159
miR-454 suppresses the proliferation and invasion of ovarian cancer by targeting E2F6.
An Y, Zhang J, Cheng X, Li B, Tian Y, Zhang X, Zhao F
Cancer cell international 2020;20:237
Cancer cell international 2020;20:237
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration.
Liu H, Liao W, Fan L, Zheng Z, Liu D, Zhang QW, Yang A, Liu F
Chinese medicine 2020;15:11
Chinese medicine 2020;15:11
GRHL2 Upregulation Predicts a Poor Prognosis and Promotes the Resistance of Serous Ovarian Cancer to Cisplatin.
Nie Y, Ding Y, Yang M
OncoTargets and therapy 2020;13:6303-6314
OncoTargets and therapy 2020;13:6303-6314
A Novel lncRNA ENST00000512916 Facilitates Cell Proliferation, Migration and Cell Cycle Progression in Ameloblastoma.
Sun Y, Niu X, Wang G, Qiao X, Chen L, Zhong M
OncoTargets and therapy 2020;13:1519-1531
OncoTargets and therapy 2020;13:1519-1531
NCAPG Induces Cell Proliferation in Cardia Adenocarcinoma via PI3K/AKT Signaling Pathway.
Zhang X, Wang H, Han Y, Zhu M, Song Z, Zhan D, Jia J
OncoTargets and therapy 2020;13:11315-11326
OncoTargets and therapy 2020;13:11315-11326
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
Guo W, Zhao L, Wei G, Liu P, Zhang Y, Fu L
Cancer management and research 2020;12:7291-7303
Cancer management and research 2020;12:7291-7303
A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.
Pan B, Wang Y, Wu C, Jia J, Huang C, Fang S, Liu L
Frontiers in pharmacology 2020;11:592903
Frontiers in pharmacology 2020;11:592903
CDC27 Promotes Tumor Progression and Affects PD-L1 Expression in T-Cell Lymphoblastic Lymphoma.
Song Y, Song W, Li Z, Song W, Wen Y, Li J, Xia Q, Zhang M
Frontiers in oncology 2020;10:488
Frontiers in oncology 2020;10:488
Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression.
Wang Z, Zhao Y, Zhao H, Zhou J, Feng D, Tang F, Li Y, Lv L, Chen Z, Ma X, Tian X, Yao J
Molecular therapy. Nucleic acids 2020 Sep 4;21:751-763
Molecular therapy. Nucleic acids 2020 Sep 4;21:751-763
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Guo X, Dai X, Liu J, Cheng A, Qin C, Wang Z
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer.
Yang Z, Wang T, Wu D, Min Z, Tan J, Yu B
Journal of experimental & clinical cancer research : CR 2020 Sep 29;39(1):203
Journal of experimental & clinical cancer research : CR 2020 Sep 29;39(1):203
Let-7b downgrades CCND1 to repress osteogenic proliferation and differentiation of MC3T3-E1 cells: An implication in osteoporosis.
Wang LJ, Cai HQ
The Kaohsiung journal of medical sciences 2020 Oct;36(10):775-785
The Kaohsiung journal of medical sciences 2020 Oct;36(10):775-785
Fatty acid synthase contributes to epithelial-mesenchymal transition and invasion of salivary adenoid cystic carcinoma through PRRX1/Wnt/β-catenin pathway.
Zhang WL, Wang SS, Jiang YP, Liu Y, Yu XH, Wu JB, Wang K, Pang X, Liao P, Liang XH, Tang YL
Journal of cellular and molecular medicine 2020 Oct;24(19):11465-11476
Journal of cellular and molecular medicine 2020 Oct;24(19):11465-11476
CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer.
Cui Y, Song Y, Yan S, Cao M, Huang J, Jia D, Liu Y, Zhang S, Fan W, Cai L, Li C, Xing Y
Aging 2020 Oct 25;12(20):20047-20068
Aging 2020 Oct 25;12(20):20047-20068
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Chen Y, Niu J, Li L, Li Z, Jiang J, Zhu M, Dong T, Zhang J, Shi C, Xu P, Lu Y, Jiang Y, Liu P, Chen W
Life sciences 2020 Oct 1;258:118158
Life sciences 2020 Oct 1;258:118158
Anthocyanins from Aronia melanocarpa Induce Apoptosis in Caco-2 Cells through Wnt/β-Catenin Signaling Pathway.
Wei J, Yu W, Hao R, Fan J, Gao J
Chemistry & biodiversity 2020 Nov;17(11):e2000654
Chemistry & biodiversity 2020 Nov;17(11):e2000654
LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.
Jin X, Ge LP, Li DQ, Shao ZM, Di GH, Xu XE, Jiang YZ
Molecular cancer 2020 May 11;19(1):87
Molecular cancer 2020 May 11;19(1):87
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Chen T, Lei S, Zeng Z, Pan S, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
International journal of molecular medicine 2020 Mar;45(3):886-896
International journal of molecular medicine 2020 Mar;45(3):886-896
Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.
Gucer H, Caliskan S, Kefeli M, Mete O
Endocrine pathology 2020 Mar;31(1):33-38
Endocrine pathology 2020 Mar;31(1):33-38
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
Yu C, Cheng Z, Cui S, Mao X, Li B, Fu Y, Wang H, Jin H, Ye Q, Zhao X, Jiang L, Qin W
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest.
Zeng ZM, Du HY, Xiong L, Zeng XL, Zhang P, Cai J, Huang L, Liu AW
Life sciences 2020 Mar 1;244:117342
Life sciences 2020 Mar 1;244:117342
Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota.
Wang D, Zhu X, Tang X, Li H, Yizhen X, Chen D
Journal of food science 2020 Jun;85(6):1872-1890
Journal of food science 2020 Jun;85(6):1872-1890
Cell adhesion molecule 4 suppresses cell growth and metastasis by inhibiting the Akt signaling pathway in non-small cell lung cancer.
Luo F, Zhao Y, Liu J
The international journal of biochemistry & cell biology 2020 Jun;123:105750
The international journal of biochemistry & cell biology 2020 Jun;123:105750
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Zheng Y, Nie P, Xu S
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway.
Yan X, Yang C, Hu W, Chen T, Wang Q, Pan F, Qiu B, Tang B
Oncology reports 2020 Jul;44(1):103-114
Oncology reports 2020 Jul;44(1):103-114
Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer.
Zhou H, Xiong Y, Zhang G, Liu Z, Li L, Hou S, Zhou T
Bioscience reports 2020 Jul 31;40(7)
Bioscience reports 2020 Jul 31;40(7)
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
Wang B, Ye Q, Zou C
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression.
Dang Y, An Y, He J, Huang B, Zhu J, Gao M, Zhang S, Wang X, Yang B, Xie Z
Aging cell 2020 Jan;19(1):e13060
Aging cell 2020 Jan;19(1):e13060
HOTAIR-EZH2 inhibitor AC1Q3QWB upregulates CWF19L1 and enhances cell cycle inhibition of CDK4/6 inhibitor palbociclib in glioma.
Shi J, Lv S, Wu M, Wang X, Deng Y, Li Y, Li K, Zhao H, Zhu X, Ye M
Clinical and translational medicine 2020 Jan;10(1):182-198
Clinical and translational medicine 2020 Jan;10(1):182-198
Knockdown of Rab9 Suppresses the Progression of Gastric Cancer Through Regulation of Akt Signaling Pathway.
Zhu Y, Shi F, Wang M, Ding J
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820915958
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820915958
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Ying Y, Li J, Xie H, Yan H, Jin K, He L, Ma X, Wu J, Xu X, Fang J, Wang X, Zheng X, Liu B, Xie L
Cell proliferation 2020 Feb;53(2):e12751
Cell proliferation 2020 Feb;53(2):e12751
Neutrophil extracellular traps mediate the crosstalk between glioma progression and the tumor microenvironment via the HMGB1/RAGE/IL-8 axis.
Zha C, Meng X, Li L, Mi S, Qian D, Li Z, Wu P, Hu S, Zhao S, Cai J, Liu Y
Cancer biology & medicine 2020 Feb 15;17(1):154-168
Cancer biology & medicine 2020 Feb 15;17(1):154-168
ERO1L promotes NSCLC development by modulating cell cycle-related molecules.
Shi X, Wu J, Liu Y, Jiang Y, Zhi C, Li J
Cell biology international 2020 Dec;44(12):2473-2484
Cell biology international 2020 Dec;44(12):2473-2484
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
Zhao Q, Sun P, Qin S, Liu J
Environmental toxicology 2020 Dec;35(12):1299-1307
Environmental toxicology 2020 Dec;35(12):1299-1307
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
Wang Z, Qi Y, Wang R, Wu W, Li Z, Wang M, Liu R, Zhang C, Li W, Wang S
Journal of cellular physiology 2020 Dec;235(12):9538-9556
Journal of cellular physiology 2020 Dec;235(12):9538-9556
lncRNA RP11-624L4.1 Is Associated with Unfavorable Prognosis and Promotes Proliferation via the CDK4/6-Cyclin D1-Rb-E2F1 Pathway in NPC.
Zhou L, Liu R, Liang X, Zhang S, Bi W, Yang M, He Y, Jin J, Li S, Yang X, Fu J, Zhang P
Molecular therapy. Nucleic acids 2020 Dec 4;22:1025-1039
Molecular therapy. Nucleic acids 2020 Dec 4;22:1025-1039
siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation.
Osana S, Kitajima Y, Suzuki N, Xu Y, Murayama K, Nagatomi R
Experimental cell research 2020 Dec 1;397(1):112337
Experimental cell research 2020 Dec 1;397(1):112337
Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells.
Zhang L, Wang Z, Kong D, Zhao X, Chen X, Chai W
Bioscience, biotechnology, and biochemistry 2020 Aug;84(8):1603-1613
Bioscience, biotechnology, and biochemistry 2020 Aug;84(8):1603-1613
Magnetic targeting enhances the cutaneous wound healing effects of human mesenchymal stem cell-derived iron oxide exosomes.
Li X, Wang Y, Shi L, Li B, Li J, Wei Z, Lv H, Wu L, Zhang H, Yang B, Xu X, Jiang J
Journal of nanobiotechnology 2020 Aug 14;18(1):113
Journal of nanobiotechnology 2020 Aug 14;18(1):113
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
Wu J, He J, Tian X, Li H, Wen Y, Shao Q, Cheng C, Wang G, Sun X
Neuroscience 2020 Aug 1;440:160-174
Neuroscience 2020 Aug 1;440:160-174
METTL3/YTHDF2 m(6) A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
Xie H, Li J, Ying Y, Yan H, Jin K, Ma X, He L, Xu X, Liu B, Wang X, Zheng X, Xie L
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
Mechanism of inhibiting proliferation of hepatocellular carcinoma Hepa1-6 cells by embryonic stem cell-conditioned medium.
Li L, Zheng Y, Zheng Q, Jiang J
Experimental and therapeutic medicine 2020 Apr;19(4):2406-2414
Experimental and therapeutic medicine 2020 Apr;19(4):2406-2414
Effect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways.
Yu ZY, Jiang XY, Zhao RR, Qin JJ, Luo CJ, Ren YX, Ren W, Ma ZJ, Jiao ZY
Chinese medical journal 2020 Apr 20;133(8):919-928
Chinese medical journal 2020 Apr 20;133(8):919-928
Loss of hnRNPA2B1 inhibits malignant capability and promotes apoptosis via down-regulating Lin28B expression in ovarian cancer.
Yang Y, Wei Q, Tang Y, Yuanyuan Wang, Luo Q, Zhao H, He M, Wang H, Zeng Q, Lu W, Xu J, Liu T, Yi P
Cancer letters 2020 Apr 10;475:43-52
Cancer letters 2020 Apr 10;475:43-52
UHRF1 Promotes Proliferation of Human Adipose-Derived Stem Cells and Suppresses Adipogenesis via Inhibiting Peroxisome Proliferator-Activated Receptor γ.
Chen K, Guo Z, Luo Y, Yuan J, Mo Z
BioMed research international 2019;2019:9456847
BioMed research international 2019;2019:9456847
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
Zhang C, Wang B, Wang X, Sheng X, Cui Y
Cancer cell international 2019;19:339
Cancer cell international 2019;19:339
HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer.
Li F, Su M, Zhao H, Xie W, Cao S, Xu Y, Chen W, Wang L, Hou L, Tan W
American journal of translational research 2019;11(11):7035-7048
American journal of translational research 2019;11(11):7035-7048
Oxymatrine Inhibits the Proliferation and Invasion of Breast Cancer Cells via the PI3K Pathway.
Guo L, Yang T
Cancer management and research 2019;11:10499-10508
Cancer management and research 2019;11:10499-10508
miR-671-5p Inhibits Tumor Proliferation by Blocking Cell Cycle in Osteosarcoma.
Xin C, Lu S, Li Y, Zhang Y, Tian J, Zhang S, Yang S, Gao T, Xu J
DNA and cell biology 2019 Sep;38(9):996-1004
DNA and cell biology 2019 Sep;38(9):996-1004
REG4 is an indicator for KRAS mutant lung adenocarcinoma with TTF-1 low expression.
Sun S, Hu Z, Huang S, Ye X, Wang J, Chang J, Wu X, Wang Q, Zhang L, Hu X, Yu H
Journal of cancer research and clinical oncology 2019 Sep;145(9):2273-2283
Journal of cancer research and clinical oncology 2019 Sep;145(9):2273-2283
Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway.
Cui Y, Zhang L, Wang W, Ma S, Liu H, Zang X, Zhang Y, Guan F
Molecular and cellular biochemistry 2019 Oct;460(1-2):93-103
Molecular and cellular biochemistry 2019 Oct;460(1-2):93-103
Upregulation of ERp57 promotes clear cell renal cell carcinoma progression by initiating a STAT3/ILF3 feedback loop.
Liu Y, Wang JX, Nie ZY, Wen Y, Jia XJ, Zhang LN, Duan HJ, Shi YH
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):439
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):439
Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism.
Yap JLY, Tai YK, Fröhlich J, Fong CHH, Yin JN, Foo ZL, Ramanan S, Beyer C, Toh SJ, Casarosa M, Bharathy N, Kala MP, Egli M, Taneja R, Lee CN, Franco-Obregón A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12853-12872
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12853-12872
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Lanxiang W, Bin W, Ge X, Yutang H, Chunjie W, Honghao Z
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.
Su D, Zhang D, Jin J, Ying L, Han M, Chen K, Li B, Wu J, Xie Z, Zhang F, Lin Y, Cheng G, Li JY, Huang M, Wang J, Wang K, Zhang J, Li F, Xiong L, Futreal A, Mao W
Nature communications 2019 Nov 7;10(1):5076
Nature communications 2019 Nov 7;10(1):5076
Forkhead Box R2 Knockdown Decreases Chemoresistance to Cisplatin via MYC Pathway in Bladder Cancer.
Li Y, Zu X, Hu X, Wang L, He W
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 25;25:8928-8939
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 25;25:8928-8939
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Shen J, Wang J, Du J, Wang L, Zhou X, Chang X, Li Z, Zhai X, Zuo D, Wu Y
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Upregulation of lncRNA DGCR5 correlates with better prognosis and inhibits bladder cancer progression via transcriptionally facilitating P21 expression.
Fang C, He W, Xu T, Dai J, Xu L, Sun F
Journal of cellular physiology 2019 May;234(5):6254-6262
Journal of cellular physiology 2019 May;234(5):6254-6262
PLAGL2 and POFUT1 are regulated by an evolutionarily conserved bidirectional promoter and are collaboratively involved in colorectal cancer by maintaining stemness.
Li D, Lin C, Li N, Du Y, Yang C, Bai Y, Feng Z, Su C, Wu R, Song S, Yan P, Chen M, Jain A, Huang L, Zhang Y, Li X
EBioMedicine 2019 Jul;45:124-138
EBioMedicine 2019 Jul;45:124-138
Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer.
Li Y, Kong R, Chen H, Zhao Z, Li L, Li J, Hu J, Zhang G, Pan S, Wang Y, Wang G, Chen H, Sun B
Aging 2019 Jul 21;11(14):5035-5057
Aging 2019 Jul 21;11(14):5035-5057
[MiR-222-3р Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2].
Yang DL, Gan ML, Tan Y, Ge GH, Li Q, Jiang YZ, Tang GQ, Li MZ, Wang JY, Li XW, Zhang SH, Zhu L
Molekuliarnaia biologiia 2019 Jan-Feb;53(1):44-52
Molekuliarnaia biologiia 2019 Jan-Feb;53(1):44-52
MiR-26b suppresses hepatocellular carcinoma development by negatively regulating ZNRD1 and Wnt/β-catenin signaling.
Hu X, Wang R, Ren Z, Liu X, Gu J, Cui G, Li Q
Cancer medicine 2019 Dec;8(17):7359-7371
Cancer medicine 2019 Dec;8(17):7359-7371
Glycogen phosphorylase B promotes ovarian cancer progression via Wnt/β-catenin signaling and is regulated by miR-133a-3p.
Zhou Y, Jin Z, Wang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109449
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109449
Phenotypic transition of tumor cells between epithelial- and mesenchymal-like state during adaptation to acidosis.
Zhang Y, Xu L, Wang P, Jian H, Shi X, Jia M, Mo L, Hu Z, Li H, Li J
Cell cycle (Georgetown, Tex.) 2019 Aug;18(16):1938-1947
Cell cycle (Georgetown, Tex.) 2019 Aug;18(16):1938-1947
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
Que Z, Zhou Z, Luo B, Dong C, Jiang Y, Li H, Tian J
BMC complementary and alternative medicine 2019 Aug 7;19(1):204
BMC complementary and alternative medicine 2019 Aug 7;19(1):204
miR-10b promoted melanoma progression through Wnt/β-catenin pathway by repressing ITCH expression.
Wang S, Wu Y, Xu Y, Tang X
Gene 2019 Aug 20;710:39-47
Gene 2019 Aug 20;710:39-47
lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.
Du Y, Wang L, Chen S, Liu Y, Zhao Y
Molecular carcinogenesis 2018 Sep;57(9):1191-1200
Molecular carcinogenesis 2018 Sep;57(9):1191-1200
Role of Daucosterol Linoleate on Breast Cancer: Studies on Apoptosis and Metastasis.
Han B, Jiang P, Liu W, Xu H, Li Y, Li Z, Ma H, Yu Y, Li X, Ye X
Journal of agricultural and food chemistry 2018 Jun 20;66(24):6031-6041
Journal of agricultural and food chemistry 2018 Jun 20;66(24):6031-6041
Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.
Tian Y, He J, Liu N, Huang D, Liu Z, Yang Y, Chen J, Zhao B, Zhao S, Liang B
RSC advances 2018 Jun 13;8(39):21759-21767
RSC advances 2018 Jun 13;8(39):21759-21767
The natural agent rhein induces β-catenin degradation and tumour growth arrest.
Liu S, Wang J, Shao T, Song P, Kong Q, Hua H, Luo T, Jiang Y
Journal of cellular and molecular medicine 2018 Jan;22(1):589-599
Journal of cellular and molecular medicine 2018 Jan;22(1):589-599
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
Cao N, Ma X, Guo Z, Zheng Y, Geng S, Meng M, Du Z, Lin H, Duan Y, Du G
Oncotarget 2016 Sep 20;7(38):61093-61106
Oncotarget 2016 Sep 20;7(38):61093-61106
KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.
Li X, He Y, Xu Y, Huang X, Liu J, Xie M, Liu X
American journal of physiology. Lung cellular and molecular physiology 2016 Feb 15;310(4):L299-310
American journal of physiology. Lung cellular and molecular physiology 2016 Feb 15;310(4):L299-310
Modulation of cyclins and p53 in mesangial cell proliferation and apoptosis during Habu nephritis.
Lu Y, Wen J, Chen D, Wu L, Li Q, Xie Y, Wu D, Liu X, Chen X
Clinical and experimental nephrology 2016 Apr;20(2):178-86
Clinical and experimental nephrology 2016 Apr;20(2):178-86
FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.
Peng X, Luo Z, Kang Q, Deng D, Wang Q, Peng H, Wang S, Wei Z
Cancer biology & therapy 2015;16(7):1099-109
Cancer biology & therapy 2015;16(7):1099-109
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Hao L, Zhou X, Liu S, Sun M, Song Y, Du S, Sun B, Guo C, Gong L, Hu J, Guan H, Shao S
Proteomics 2015 Sep;15(17):3087-100
Proteomics 2015 Sep;15(17):3087-100
GOLPH3 is a potential therapeutic target and a prognostic indicator of poor survival in bladder cancer treated by cystectomy.
Zhang Q, Zhuang J, Deng Y, Zhao X, Tang B, Yao D, Zhao W, Chang C, Lu Q, Chen W, Zhang S, Ji C, Cao L, Guo H
Oncotarget 2015 Oct 13;6(31):32177-92
Oncotarget 2015 Oct 13;6(31):32177-92
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