10-7574

antibody from ABEOMICS Inc.

Targeting: CCND1 BCL1, D11S287E, PRAD1, U21B31

Antibody data

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Validation data

Product number: 10-7574 - Provider product page
Provider: ABEOMICS Inc.
Product name: Anti-Cyclin D1 Antibody
Antibody type: Monoclonal
Description: Cyclin D1 (CCND1) is an important positive regulator of the G1/S phase of the cell cycle. It regulate cell cycle transition from G1 phase to S phase It is a well-established human oncogene which is frequently amplified or overexpressed in cancers (25409185). Cyclin D1b is one of two proteins translated from Cyclin D1 transcripts (isoforms a and b) that are generated due to gene polymorphism. Low Cyclin D1b expression in cervical cancer tissue, with an expression level in moderately or poorly differentiated tissues was significantly lower than that in well-differentiated tissues (25120779). Diseases associated with CCND1 include multiple myeloma and mantle cell lymphoma.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: A partial length recombinant Cyclin D1 protein (amino acids 107-275) w as used as the immunogen for this a ntibody.
Isotype: IgG
Antibody clone number: ABM47F5
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing

CCND1 protein structure - 10-7574 shown in red.