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- References [304]
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- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- MA5-16356 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Cyclin D1 Recombinant Rabbit Monoclonal Antibody (SP4)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Description
- This antibody is predicted to react with mouse and rat based on sequence homology.
- Antibody clone number
- SP4
- Concentration
- 0.045 mg/mL
Submitted references Additive Effect of CD73 Inhibitor in Colorectal Cancer Treatment With CDK4/6 Inhibitor Through Regulation of PD-L1.
IKKα Induces Epithelial-Mesenchymal Changes in Mouse Skin Carcinoma Cells That Can Be Partially Reversed by Apigenin.
Aberrant expression of semaphorin 6B affects cell phenotypes in thyroid carcinoma by activating the Notch signalling pathway.
Circ-UBAP2 functions as sponges of miR-1205 and miR-382 to promote glioma progression by modulating STC1 expression.
The function and mechanism of the JARID2/CCND1 axis in modulating glioma cell growth and sensitivity to temozolomide (TMZ).
Transmembrane protein ADAM29 facilitates cell proliferation, invasion and migration in clear cell renal cell carcinoma.
Implications of cell division cycle associated 4 on the Wilm's tumor cells viability via AKT/mTOR signaling pathway.
Stapled peptide targeting the CDK4/Cyclin D interface combined with Abemaciclib inhibits KRAS mutant lung cancer growth.
Involvement of MicroRNA-1-FAM83A Axis Dysfunction in the Growth and Motility of Lung Cancer Cells.
A 30-Year Long-Term Experience in Appendix Neuroendocrine Neoplasms-Granting a Positive Outcome.
Development of prediction models for lymph node metastasis in endometrioid endometrial carcinoma.
STAT3 is a key molecule in the oncogenic behavior of diffuse intrinsic pontine glioma.
Phosphorylation of eukaryotic initiation factor 4E is dispensable for skeletal muscle hypertrophy.
Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis.
Modeling Wnt signaling by CRISPR-Cas9 genome editing recapitulates neoplasia in human Barrett epithelial organoids.
Association of p27 and Cyclin D1 Expression and Benefit from Adjuvant Trastuzumab Treatment in HER2-Positive Early Breast Cancer: A TransHERA Study.
Clear cell sarcomas of the kidney are characterised by BCOR gene abnormalities, including exon 15 internal tandem duplications and BCOR-CCNB3 gene fusion.
Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation.
High-Risk HPV, Biomarkers, and Outcome in Matched Cohorts of Head and Neck Cancer Patients Positive and Negative for HIV.
Primary cardiac diffuse large B-cell lymphoma in immunocompetent patients: clinical, histologic, immunophenotypic, and genotypic features of 3 cases.
In Utero Exposure to Valproic Acid Induces Neocortical Dysgenesis via Dysregulation of Neural Progenitor Cell Proliferation/Differentiation.
Renal cell carcinoma in kidney allografts: histologic types, including biphasic papillary carcinoma.
Cyclin D1 expression in peripheral T-cell lymphomas.
MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration.
Arm Selection Preference of MicroRNA-193a Varies in Breast Cancer.
The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells.
Everolimus-induced epithelial to mesenchymal transition (EMT) in bronchial/pulmonary cells: when the dosage does matter in transplantation.
Overexpression of β-Catenin and Cyclin D1 is Associated with Poor Overall Survival in Patients with Stage IA-IIA Squamous Cell Lung Cancer Irrespective of Adjuvant Chemotherapy.
Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages.
Survivin and cycline D1 expressions are associated with malignant potential in mucinous ovarian neoplasms.
Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.
Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome.
miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway.
Concurrent radiotherapy with gefitinib in elderly patients with esophageal squamous cell carcinoma: Preliminary results of a phase II study.
Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance.
Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex.
Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies.
Altered PPP2R2A and Cyclin D1 expression defines a subgroup of aggressive luminal-like breast cancer.
In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells.
The role of core needle biopsy in the preoperative diagnosis of follicular neoplasm of the thyroid.
Sequential immunohistochemistry: a promising new tool for the pathology laboratory.
Development of a conditionally immortalized human pancreatic β cell line.
Immunohistochemical and FISH analysis of EGFR and its prognostic value in patients with oral squamous cell carcinoma.
Longer survival in patients with breast cancer with cyclin d1 over-expression after tumor recurrence: longer, but occupied with disease.
A growth-promoting signaling component cyclin D1 in neural stem cells has antiastrogliogenic function to execute self-renewal.
Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes.
The expression of apoptosis inducing factor (AIF) is associated with aging-related cell death in the cortex but not in the hippocampus in the TgCRND8 mouse model of Alzheimer's disease.
Immunohistochemistry-based subtyping of breast carcinoma in Egyptian women: a clinicopathologic study on 125 patients.
Well-differentiated follicular patterned tumors of the thyroid with high-grade features can metastasize in the absence of capsular or vascular invasion: report of a case.
4EGI-1 targets breast cancer stem cells by selective inhibition of translation that persists in CSC maintenance, proliferation and metastasis.
A tissue quality index: an intrinsic control for measurement of effects of preanalytical variables on FFPE tissue.
Chromosome instability predicts progression of premalignant lesions of the larynx.
Expression Profiling of Proliferation and Apoptotic Markers along the Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis Patients.
Cyclin D1 is required for proliferation of Olig2-expressing progenitor cells in the injured cerebral cortex.
The THO ribonucleoprotein complex is required for stem cell homeostasis in the adult mouse small intestine.
Florid lobular carcinoma in situ: molecular profiling and comparison to classic lobular carcinoma in situ and pleomorphic lobular carcinoma in situ.
The impact of molecular morphology techniques on the expert diagnosis in melanocytic skin neoplasms.
Cooperation between Dmp1 loss and cyclin D1 overexpression in breast cancer.
The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit.
Identification of novel target proteins in sebaceous gland carcinoma.
Regional differences in gallbladder cancer pathogenesis: insights from a comparison of cell cycle-regulatory, PI3K, and pro-angiogenic protein expression.
SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity.
Immunohistochemical analysis of the expression of MAGE-A and NY-ESO-1 cancer/testis antigens in diffuse large B-cell testicular lymphoma.
Diffuse large B-cell lymphoma of the ocular adnexal region: a nation-based study.
The PPARγ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency.
Diffuse large B-cell lymphoma and mantle cell lymphoma of the ocular adnexal region, and lymphoma of the lacrimal gland: an investigation of clinical and histopathological features.
Clonally related follicular lymphomas and Langerhans cell neoplasms: expanding the spectrum of transdifferentiation.
Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a clinicopathologic and molecular study.
Plant stanols induce intestinal tumor formation by up-regulating Wnt and EGFR signaling in Apc Min mice.
Correct timing of proliferation and differentiation is necessary for normal inner ear development and auditory hair cell viability.
MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism.
Clonally related composite follicular lymphoma and mantle cell lymphoma with clinicopathologic features and biological implications.
A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.
The CDKN2A and MAP kinase pathways: molecular roads to primary oral mucosal melanoma.
VR09 cell line: an EBV-positive lymphoblastoid cell line with in vivo characteristics of diffuse large B cell lymphoma of activated B-cell type.
COUP-TFII controls mouse pancreatic β-cell mass through GLP-1-β-catenin signaling pathways.
Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood.
Cyclin D1 overexpression associates with favourable prognostic factors in invasive breast carcinoma.
Cyclin D1 induction preceding neuronal death via the excitotoxic NMDA pathway involves selective stimulation of extrasynaptic NMDA receptors and JNK pathway.
SMARCB1/INI1 inactivation in renal medullary carcinoma.
CD5-positive mucosa-associated lymphoid tissue (MALT) lymphoma: a clinicopathologic study of 14 cases.
Attenuation of the retinoblastoma pathway in pancreatic neuroendocrine tumors due to increased cdk4/cdk6.
Cell cycle regulation in mouse heart during embryonic and postnatal stages.
Genetic characterization of mesenchymal, clear cell, and dedifferentiated chondrosarcoma.
Fibrin-associated large B-cell lymphoma: part of the spectrum of cardiac lymphomas.
UM-SCC-104: a new human papillomavirus-16-positive cancer stem cell-containing head and neck squamous cell carcinoma cell line.
Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres.
Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer.
The 3-layered ductal epithelium in gynecomastia.
Prognostic role of SOX11 in a population-based cohort of mantle cell lymphoma.
Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis.
Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development.
EBV+ diffuse large B-cell lymphoma arising within atrial myxoma. An example of a distinct primary cardiac EBV+ DLBCL of immunocompetent patients.
Endometrial tumorigenesis in Pten(+/-) mice is independent of coexistence of estrogen and estrogen receptor α.
Cyclin D1 and FADD as biomarkers in head and neck squamous cell carcinoma.
γ-Tocotrienol inhibits cell viability through suppression of β-catenin/Tcf signaling in human colon carcinoma HT-29 cells.
FADD expression as a prognosticator in early-stage glottic squamous cell carcinoma of the larynx treated primarily with radiotherapy.
Early changes in carcinogenesis of colorectal adenomas.
Early changes in carcinogenesis of colorectal adenomas.
Evaluation of immunohistochemical expression of p53, p21, p27, cyclin D1, and Ki67 in oral and oropharyngeal squamous cell carcinoma.
Alteration of G1/S transition regulators influences recurrences in head and neck squamous carcinomas.
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Routine pathologic parameters can predict Oncotype DX recurrence scores in subsets of ER positive patients: who does not always need testing?
A rare S33C mutation of CTNNB1 encoding β-catenin in a parathyroid adenoma found in an Italian primary hyperparathyroid cohort.
Reduced chondrocyte proliferation, earlier cell cycle exit and increased apoptosis in neuronal nitric oxide synthase-deficient mice.
FOXA1 promotes tumor progression in prostate cancer and represents a novel hallmark of castration-resistant prostate cancer.
Cyclin D1 overexpression and poor clinical outcomes in Taiwanese oral cavity squamous cell carcinoma.
Immunophenotyping of male breast cancer.
Cyclin D1, E-cadherin and beta-catenin expression in FIGO Stage IA cervical squamous carcinoma: diagnostic value and evidence for epithelial-mesenchymal transition.
Prognostic and predictive markers in medullary thyroid carcinoma.
Biomarkers of parathyroid carcinoma.
Quantitative assessment of effect of preanalytic cold ischemic time on protein expression in breast cancer tissues.
Pulmonary involvement by chronic lymphocytic leukemia/small lymphocytic lymphoma is a specific pathologic finding independent of inflammatory infiltration.
Identification of prognostic biomarkers for glioblastomas using protein expression profiling.
Restrictions in cell cycle progression of adult vestibular supporting cells in response to ectopic cyclin D1 expression.
Transgenic expression of entire hepatitis B virus in mice induces hepatocarcinogenesis independent of chronic liver injury.
Comparative analysis of biological profiles of benign prostate hyperplasia and prostate cancer as potential diagnostic, prognostic and predictive indicators.
Translocation (5; 11) in a conjunctival MALT lymphoma.
Delineation of chondroid lipoma: an immunohistochemical and molecular biological analysis.
An assessment of the usefulness of immunohistochemical stains in the diagnosis of hairy cell leukemia.
Small cell variant of mantle cell lymphoma is an indolent lymphoma characterized by bone marrow involvement, splenomegaly, and a low Ki-67 index.
Inducible nitric oxide synthase-nitric oxide signaling mediates the mitogenic activity of Rac1 during endochondral bone growth.
Expression of CD19 and lack of miR-223 distinguish extramedullary plasmacytoma from multiple myeloma.
Acute sensitivity of the oral mucosa to oncogenic K-ras.
Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features.
FHL2 exhibits anti-proliferative and anti-apoptotic activities in liver cancer cells.
Protein kinase Cα signaling regulates inhibitor of DNA binding 1 in the intestinal epithelium.
TNFR2 interposes the proliferative and NF-κB-mediated inflammatory response by podocytes to TNF-α.
Cyclin D1 positive diffuse large B-cell lymphoma is a post-germinal center-type lymphoma without alterations in the CCND1 gene locus.
The Forkhead factor FoxQ1 influences epithelial differentiation.
Altered expression of cell-cell adhesion molecules β-catenin/E-cadherin and related Wnt-signaling pathway in sporadic and syndromal keratocystic odontogenic tumors.
The transforming growth factor-α and cyclin D1 genes are direct targets of β-catenin signaling in hepatocyte proliferation.
Photodynamic therapy reduces the histological features of actinic damage and the expression of early oncogenic markers.
Expression and localization of E-cadherin and β-catenin in uterine carcinosarcoma.
APRIL promotes cell-cycle progression in primary multiple myeloma cells: influence of D-type cyclin group and translocation status.
Molecular characteristics of mantle cell lymphoma presenting with clonal plasma cell component.
Epithelioid/mixed phenotype in gastrointestinal stromal tumors with KIT mutation from the stomach is associated with accelerated passage of late phases of the cell cycle and shorter disease-free survival.
Effects of long-term storage on the detection of proteins, DNA, and mRNA in tissue microarray slides.
Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells.
CK5/6, EGFR, Ki-67, cyclin D1, and nm23-H1 protein expressions as predictors of pathological complete response to neoadjuvant chemotherapy in triple-negative breast cancer patients.
Flow cytometry as an accurate tool to complement fine needle aspiration cytology in the diagnosis of low grade malignant lymphomas.
Extraosseous (extramedullary) plasmacytomas: a clinicopathologic and immunophenotypic study of 32 Chinese cases.
An inexpensive method of small paraffin tissue microarrays using mechanical pencil tips.
CD5(-) diffuse large B-cell lymphoma with peculiar cyclin D1+ phenotype. Pathologic and molecular characterization of a single case.
Aberrant Wnt1/β-catenin expression is an independent poor prognostic marker of non-small cell lung cancer after surgery.
High-level cytoplasmic cyclin D1 expression in lymph node metastases from prostate cancer independently predicts early biochemical failure and death in surgically treated patients.
Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling.
Primary follicular lymphoma of the duodenum is a distinct mucosal/submucosal variant of follicular lymphoma: a retrospective study of 63 cases.
Use of cyclin D1 in conjunction with human papillomavirus status to predict outcome in oropharyngeal cancer.
Pediatric lymphomas in Brazil.
Pediatric lymphomas in Brazil.
Unique patterns of tumor growth related with the risk of lymph node metastasis in papillary thyroid carcinoma.
Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis.
Acute dyspnoea and single tracheal localisation of mantle cell lymphoma.
Immunohistochemical comparative study of the odontogenic keratocysts and other odontogenic lesions.
Immunohistochemical comparative study of the odontogenic keratocysts and other odontogenic lesions.
D-type cyclins in superficial and muscle-invasive bladder urothelial carcinoma: correlation with clinicopathological data and prognostic significance.
Immunohistochemical characteristics of diffuse sclerosing variant of papillary carcinoma: comparison with conventional papillary carcinoma.
Cyclin D1 expression in B-cell lymphomas.
Idiopathic cervical fibrosis--a new member of IgG4-related sclerosing diseases: report of 4 cases, 1 complicated by composite lymphoma.
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis.
Mantle cell lymphoma 12 years after allogeneic bone marrow transplantation occurring simultaneously in recipient and donor.
Protein profiling in pathology: analysis and evaluation of 239 frozen tissue biopsies for diagnosis of B-cell lymphomas.
Primary plasmacytoma of the cervix in a 21-year-old female patient.
Characterization of D-cyclin proteins in hematolymphoid neoplasms: lack of specificity of cyclin-D2 and D3 expression in lymphoma subtypes.
Most morphologic features in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) do not reliably predict underlying FISH genetics or immunoglobulin heavy chain variable region somatic mutational status.
The checkpoint kinase ATM protects against stress-induced elevation of cyclin D1 and potential cell death in neurons.
p16 and pRb immunohistochemical expression increases with increasing tumour grade in mammary phyllodes tumours.
Impact of RING and BRCT domain mutations on BRCA1 protein stability, localization and recruitment to DNA damage.
Morphological and immunophenotypic features of primary and metastatic giant cell tumour of bone.
Citraconic anhydride: a new antigen retrieval solution.
Papillary microcarcinoma in comparison with larger papillary thyroid carcinoma in BRAF(V600E) mutation, clinicopathological features, and immunohistochemical findings.
Cell cycle regulation in the inner ear sensory epithelia: role of cyclin D1 and cyclin-dependent kinase inhibitors.
Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type.
The role of immunohistochemistry in discriminating primary from secondary extramammary Paget disease.
CD20-positive multiple myeloma - differential expression of cyclins D1 and D2 suggests a heterogeneous disease.
Diagnostic and differential diagnostic criteria of lymphoid neoplasms in bone marrow trephine biopsies: a study of 87 cases.
Targets for molecular therapy in esophageal squamous cell carcinoma: an immunohistochemical analysis.
Differences in protein expression and gene amplification of cyclins between colon and rectal adenocarcinomas.
Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer.
A novel small molecule with potent anticancer activity inhibits cell growth by modulating intracellular labile zinc homeostasis.
CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differentiation from chromophobe renal cell carcinoma.
Improved diagnostic segregation of mantle cell lymphoma by determination of cyclin D1/D3 expression ratio in formalin-fixed tissue.
Clinical and biological significance of CDK4 amplification in well-differentiated and dedifferentiated liposarcomas.
Complex analysis of cyclin D1 expression in mantle cell lymphoma: two cyclin D1-negative cases detected.
Lumican inhibits B16F1 melanoma cell lung metastasis.
Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer.
Reduced p16 and increased cyclin D1 and pRb expression are correlated with progression in cutaneous melanocytic tumors.
Differential diagnosis of cyclin D2+ mantle cell lymphoma based on fluorescence in situ hybridization and quantitative real-time-PCR.
Comparative clinicopathologic and immunohistochemical analysis of uterine sarcomas diagnosed using the World Health Organization classification system.
IgG4-related Sclerosing disease: a potential new etiology of cutaneous pseudolymphoma.
Diffuse blastoid B-cell lymphoma: a histologically aggressive variant of t(14;18)-negative follicular lymphoma.
Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation.
Mantle cell lymphoma with flow cytometric evidence of clonal plasmacytic differentiation: a case report.
Marginal zone variant of mantle cell lymphoma: CD5-negative cyclin D1-positive variant posing a diagnostic dilemma.
Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice.
Epstein-Barr virus-positive B-cell lymphoma of the elderly at a United States tertiary medical center: an uncommon aggressive lymphoma with a nongerminal center B-cell phenotype.
Determinants of response to epidermal growth factor receptor tyrosine kinase inhibition in squamous cell carcinoma of the head and neck.
Loss of VHL and hypoxia provokes PAX2 up-regulation in clear cell renal cell carcinoma.
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.
Clinical significance of cyclin D1, fibroblast growth factor receptor 3, and p53 immunohistochemistry in plasma cell myeloma treated with a thalidomide-based regimen.
Immunohistochemical evaluation of 95 bone marrow reactive plasmacytoses.
IgG4-related sclerosing mastitis: description of a new member of the IgG4-related sclerosing diseases.
Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis.
Clinical and immunohistochemical features associated with a response to bortezomib in patients with multiple myeloma.
Role of cyclin D1 as a mediator of c-Met- and beta-catenin-induced hepatocarcinogenesis.
Radiotherapy in laryngeal carcinoma: can a panel of 13 markers predict response?
Lithium chloride treatment induces epithelial cell proliferation in xenografted human endometrium.
The in vivo modulatory effects of an anterior-chamber microenvironment on uveal melanoma.
CD43 expression is an adverse prognostic factor in diffuse large B-Cell lymphoma.
Glycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapy.
Jagged 1 is necessary for normal mouse lens formation.
Stromal, fibrous, and fatty gastrointestinal tumors in a patient with a PDGFRA gene mutation.
Morphologic features of 115 lymphomas of the orbit and ocular adnexa categorized according to the World Health Organization classification: are marginal zone lymphomas in the orbit mucosa-associated lymphoid tissue-type lymphomas?
Differences and molecular immunohistochemical parameters in the subtypes of infiltrating ductal breast cancer.
Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients.
Notch signaling regulates growth and differentiation in the mammalian lens.
p16, cyclin D1, Ki-67, and AMACR as markers for dysplasia in Barrett esophagus.
The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival.
Immunohistochemical and biogenetic features of diffuse-type tenosynovial giant cell tumors: the potential roles of cyclin A, P53, and deletion of 15q in sarcomatous transformation.
Exploration of the APC/beta-catenin (WNT) pathway and a histologic classification system for pulmonary artery intimal sarcoma. A study of 18 cases.
Activated Akt as an indicator of prognosis in gastric cancer.
Immunohistochemical evaluation of a panel of tumor cell markers during malignant progression in Barrett esophagus.
Heterozygous mutations in the tumor suppressor gene PATCHED provoke basal cell carcinoma-like features in human organotypic skin cultures.
Oligomeric proanthocyanidin complexes (OPC) exert anti-proliferative and pro-apoptotic effects on prostate cancer cells.
Proliferating active cells, lymphocyte subsets, and dendritic cells in recurrent tonsillitis: their effect on hypertrophy.
Cyclin D1 overexpression, p16 loss, and pRb inactivation play a key role in pulmonary carcinogenesis and have a prognostic implication for the long-term survival in non-small cell lung carcinoma patients.
S100A4 expression is associated with lymph node metastasis in papillary microcarcinoma of the thyroid.
Regulation of keratinocyte proliferation in rats with deep, partial-thickness scald: modulation of cyclin D1-cyclin-dependent kinase 4 and histone H1 kinase activity of M-phase promoting factor.
Mantle cell lymphoma lacking the t(11;14) translocation: a case report and brief review of the literature.
Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs).
MYC translocation in chronic lymphocytic leukaemia is associated with increased prolymphocytes and a poor prognosis.
Molecular characterization of synovial sarcoma in children and adolescents: evidence of akt activation.
Impaired E-cadherin expression and glutamine synthetase overexpression in solid pseudopapillary neoplasm of the pancreas.
Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells.
Gene expression profile analysis of epilepsy-associated gangliogliomas.
Effects of estradiol and medroxyprogesterone acetate on expression of the cell cycle proteins cyclin D1, p21 and p27 in cultured human breast tissues.
Effects of estradiol and medroxyprogesterone acetate on expression of the cell cycle proteins cyclin D1, p21 and p27 in cultured human breast tissues.
Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche.
Human thyroid tumours, the puzzling lessons from E7 and RET/PTC3 transgenic mice.
Chromosome 11 genomic changes in parathyroid adenoma and hyperplasia: array CGH, FISH, and tissue microarrays.
Ocular adnexal lymphoma associated with IgG4+ chronic sclerosing dacryoadenitis: a previously undescribed complication of IgG4-related sclerosing disease.
Cyclin D1 in excitatory neurons of the adult brain enhances kainate-induced neurotoxicity.
Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast.
Primary extramedullary plasmacytoma: similarities with and differences from multiple myeloma revealed by interphase cytogenetics.
Immunoexpression and prognostic role of hTERT and cyclin D1 in urothelial carcinoma.
Wnt pathway-related gene expression during malignant progression in ulcerative colitis.
The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma.
The reliability of lymphoma diagnosis in small tissue samples is heavily influenced by lymphoma subtype.
Co-expression of cyclin D1 and phosphorylated ribosomal S6 proteins in hemimegalencephaly.
Clinical outcome of incidental pelvic node malignant B-cell lymphomas discovered at the time of radical prostatectomy.
The effect of the sun on expression of beta-catenin, p16 and cyclin d1 proteins in melanocytic lesions.
Selective cortical interneuron and GABA deficits in cyclin D2-null mice.
Immunohistochemical analysis with multiple antibodies in search of prognostic markers for clear cell renal cell carcinoma.
Cyclin D1 and t(11;14)-positive B-cell neoplasms resembling marginal zone B-cell lymphoma: a morphological variant of mantle cell lymphoma.
Should parafibromin staining replace HRTP2 gene analysis as an additional tool for histologic diagnosis of parathyroid carcinoma?
Leptin-mediated decrease of cyclin A2 and increase of cyclin D1 expression: relevance for the control of prepubertal rat Leydig cell division and differentiation.
Involvement of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice.
Immunophenotypic profiling of nonsmall cell lung cancer progression using the tissue microarray approach.
Immunohistochemical expression of beta-catenin, E-cadherin, cyclin D1 and c-myc in benign trichogenic tumors.
Pathological and biological differences between screen-detected and interval ductal carcinoma in situ of the breast.
The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry.
Expression of cyclin D1 and Ki-67 in squamous cell carcinoma of the penis.
Cell cycle regulators and outcome of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer: the International Adjuvant Lung Cancer Trial Biologic Program.
Developmental expression of cell cycle regulators in the baboon fetal adrenal gland.
The t(14;19)(q32;q13)-positive small B-cell leukaemia: a clinicopathologic and cytogenetic study of seven cases.
Expression of human telomerase reverse transcriptase and cyclin-D1 in olfactory neuroblastoma.
Proximal tubular epithelial cells are generated by division of differentiated cells in the healthy kidney.
Frequency and distribution of trisomy 11 in multiple myeloma patients: relation with overexpression of CCND1 and t(11;14).
Cell cycle regulators show diagnostic and prognostic utility for differentiated thyroid cancer.
The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome in 'pure' ductal carcinoma in situ of the breast.
Diagnostic value of galectin-3, HBME-1, cytokeratin 19, high molecular weight cytokeratin, cyclin D1 and p27(kip1) in the differential diagnosis of thyroid nodules.
Synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: case report.
New evidence for geographic variation in the role of human papillomavirus in tonsillar carcinogenesis.
Overlapping morphologic and immunophenotypic profiles in small B-cell lymphoma. A report of two cases.
Tissue microarray profiling of primary and xenotransplanted synovial sarcomas demonstrates the immunophenotypic similarities existing between SYT-SSX fusion gene confirmed, biphasic, and monophasic fibrous variants.
Lymphomas involving the pleura: a clinicopathologic study of 34 cases diagnosed by pleural biopsy.
P27, SKP2, and extra-cellular signal-related kinase signalling in human salivary gland mucoepidermoid carcinoma.
Identification of target genes in laryngeal squamous cell carcinoma by high-resolution copy number and gene expression microarray analyses.
FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas.
Molecular and cytogenetic subgroups of oropharyngeal squamous cell carcinoma.
Molecular characterization of composite mantle cell and follicular lymphoma.
Overexpression of cyclins D1 and D3 during estrogen-induced breast oncogenesis in female ACI rats.
Loss of parafibromin expression in a subset of parathyroid adenomas.
Mantle cell lymphoma in Taiwan: clinicopathological and molecular study of 21 cases including one cyclin D1-negative tumor expressing cyclin D2.
Ocular adnexal marginal zone B cell lymphoma: a clinical and pathologic study of 23 cases.
Z-138 cell line was derived from a patient with blastoid variant mantle cell lymphoma.
Immunohistochemical analysis identifies two cyclin D1+ subsets of plasma cell myeloma, each associated with favorable survival.
Immunophenotypic profile of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia.
Transforming growth factor beta 1 promotes cell cycle exit through the cyclin-dependent kinase inhibitor p21 in the developing cerebral cortex.
The kd/kd mouse is a model of collapsing glomerulopathy.
Ethanol disrupts cell cycle regulation in developing rat cortex interaction with transforming growth factor beta1.
Increase in Ara-C cytotoxicity in the presence of valproate, a histone deacetylase inhibitor, is associated with the concurrent expression of cyclin D1 and p27(Kip 1) in acute myeloblastic leukemia cells.
Antibody selection in immunohistochemical detection of cyclin D1 in mantle cell lymphoma.
The cell cycle-apoptosis connection revisited in the adult brain.
Mantle cell lymphomas with low levels of cyclin D1 long mRNA transcripts are highly proliferative and can be discriminated by elevated cyclin A2 and cyclin B1.
Low level of cyclin D1 protein expression in thyroid microcarcinomas from an autopsy series.
HDPR1, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencing.
Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling.
Clinicopathologic and genetic profile of intracranial marginal zone lymphoma: a primary low-grade CNS lymphoma that mimics meningioma.
Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase-immortalized human mesenchymal stem cells.
Consistent immunostaining for cyclin D1 can be achieved on a routine basis using a newly available rabbit monoclonal antibody.
Consistent immunostaining for cyclin D1 can be achieved on a routine basis using a newly available rabbit monoclonal antibody.
The small leucine-rich proteoglycan lumican inhibits melanoma progression.
Noh JY, Lee IP, Han NR, Kim M, Min YK, Lee SY, Yun SH, Kim SI, Park T, Chung H, Park D, Lee CH
Cellular and molecular gastroenterology and hepatology 2022;14(4):769-788
Cellular and molecular gastroenterology and hepatology 2022;14(4):769-788
IKKα Induces Epithelial-Mesenchymal Changes in Mouse Skin Carcinoma Cells That Can Be Partially Reversed by Apigenin.
García-García VA, Alameda JP, Page A, Mérida-García A, Navarro M, Tejero A, Paramio JM, García-Fernández RA, Casanova ML
International journal of molecular sciences 2022 Jan 25;23(3)
International journal of molecular sciences 2022 Jan 25;23(3)
Aberrant expression of semaphorin 6B affects cell phenotypes in thyroid carcinoma by activating the Notch signalling pathway.
Lv XJ, Chen X, Wang Y, Yu S, Pang L, Huang C
Endokrynologia Polska 2021;72(1):29-36
Endokrynologia Polska 2021;72(1):29-36
Circ-UBAP2 functions as sponges of miR-1205 and miR-382 to promote glioma progression by modulating STC1 expression.
Wang J, Li T, Wang B
Cancer medicine 2021 Mar;10(5):1815-1828
Cancer medicine 2021 Mar;10(5):1815-1828
The function and mechanism of the JARID2/CCND1 axis in modulating glioma cell growth and sensitivity to temozolomide (TMZ).
Kuang W, Jiang W, Chen Y, Tian Y, Liu Z
Cancer biology & therapy 2021 Jun 3;22(5-6):392-403
Cancer biology & therapy 2021 Jun 3;22(5-6):392-403
Transmembrane protein ADAM29 facilitates cell proliferation, invasion and migration in clear cell renal cell carcinoma.
Li SL, Jiang TQ, Cao QW, Liu SM
Journal of chemotherapy (Florence, Italy) 2021 Feb;33(1):40-50
Journal of chemotherapy (Florence, Italy) 2021 Feb;33(1):40-50
Implications of cell division cycle associated 4 on the Wilm's tumor cells viability via AKT/mTOR signaling pathway.
Li S, Qin C, Chen Y, Wei D, Tan Z, Meng J
Renal failure 2021 Dec;43(1):1470-1478
Renal failure 2021 Dec;43(1):1470-1478
Stapled peptide targeting the CDK4/Cyclin D interface combined with Abemaciclib inhibits KRAS mutant lung cancer growth.
Bouclier C, Simon M, Laconde G, Pellerano M, Diot S, Lantuejoul S, Busser B, Vanwonterghem L, Vollaire J, Josserand V, Legrand B, Coll JL, Amblard M, Hurbin A, Morris MC
Theranostics 2020;10(5):2008-2028
Theranostics 2020;10(5):2008-2028
Involvement of MicroRNA-1-FAM83A Axis Dysfunction in the Growth and Motility of Lung Cancer Cells.
Liu PJ, Chen YH, Tsai KW, Yeah HY, Yeh CY, Tu YT, Yang CY
International journal of molecular sciences 2020 Nov 22;21(22)
International journal of molecular sciences 2020 Nov 22;21(22)
A 30-Year Long-Term Experience in Appendix Neuroendocrine Neoplasms-Granting a Positive Outcome.
Vinagre J, Pinheiro J, Martinho O, Reis RM, Preto J, Soares P, Lopes JM
Cancers 2020 May 26;12(6)
Cancers 2020 May 26;12(6)
Development of prediction models for lymph node metastasis in endometrioid endometrial carcinoma.
Berg HF, Ju Z, Myrvold M, Fasmer KE, Halle MK, Hoivik EA, Westin SN, Trovik J, Haldorsen IS, Mills GB, Krakstad C, Werner HMJ
British journal of cancer 2020 Mar;122(7):1014-1022
British journal of cancer 2020 Mar;122(7):1014-1022
STAT3 is a key molecule in the oncogenic behavior of diffuse intrinsic pontine glioma.
Park J, Lee W, Yun S, Kim SP, Kim KH, Kim JI, Kim SK, Wang KC, Lee JY
Oncology letters 2020 Aug;20(2):1989-1998
Oncology letters 2020 Aug;20(2):1989-1998
Phosphorylation of eukaryotic initiation factor 4E is dispensable for skeletal muscle hypertrophy.
Figueiredo VC, Englund DA, Vechetti IJ Jr, Alimov A, Peterson CA, McCarthy JJ
American journal of physiology. Cell physiology 2019 Dec 1;317(6):C1247-C1255
American journal of physiology. Cell physiology 2019 Dec 1;317(6):C1247-C1255
Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis.
Kiyama T, Chen CK, Wang SW, Pan P, Ju Z, Wang J, Takada S, Klein WH, Mao CA
Molecular neurodegeneration 2018 Oct 17;13(1):56
Molecular neurodegeneration 2018 Oct 17;13(1):56
Modeling Wnt signaling by CRISPR-Cas9 genome editing recapitulates neoplasia in human Barrett epithelial organoids.
Liu X, Cheng Y, Abraham JM, Wang Z, Wang Z, Ke X, Yan R, Shin EJ, Ngamruengphong S, Khashab MA, Zhang G, McNamara G, Ewald AJ, Lin D, Liu Z, Meltzer SJ
Cancer letters 2018 Nov 1;436:109-118
Cancer letters 2018 Nov 1;436:109-118
Association of p27 and Cyclin D1 Expression and Benefit from Adjuvant Trastuzumab Treatment in HER2-Positive Early Breast Cancer: A TransHERA Study.
Filipits M, Dafni U, Gnant M, Polydoropoulou V, Hills M, Kiermaier A, de Azambuja E, Larsimont D, Rojo F, Viale G, Toi M, Harbeck N, Prichard KI, Gelber RD, Dinh P, Zardavas D, Leyland-Jones B, Piccart-Gebhart MJ, Dowsett M, TransHERA investigators
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3079-3086
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3079-3086
Clear cell sarcomas of the kidney are characterised by BCOR gene abnormalities, including exon 15 internal tandem duplications and BCOR-CCNB3 gene fusion.
Wong MK, Ng CCY, Kuick CH, Aw SJ, Rajasegaran V, Lim JQ, Sudhanshi J, Loh E, Yin M, Ma J, Zhang Z, Iyer P, Loh AHP, Lian DWQ, Wang S, Goh SGH, Lim TH, Lim AST, Ng T, Goytain A, Loh AHL, Tan PH, Teh BT, Chang KTE
Histopathology 2018 Jan;72(2):320-329
Histopathology 2018 Jan;72(2):320-329
Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation.
Lázaro S, Pérez-Crespo M, Enguita AB, Hernández P, Martínez-Palacio J, Oteo M, Sage J, Paramio JM, Santos M
Oncotarget 2017 Jan 17;8(3):4373-4386
Oncotarget 2017 Jan 17;8(3):4373-4386
High-Risk HPV, Biomarkers, and Outcome in Matched Cohorts of Head and Neck Cancer Patients Positive and Negative for HIV.
Walline HM, Carey TE, Goudsmit CM, Bellile EL, D'Souza G, Peterson LA, McHugh JB, Pai SI, Lee JJ, Shin DM, Ferris RL, HNC SPORE HIV supplement consortium
Molecular cancer research : MCR 2017 Feb;15(2):179-188
Molecular cancer research : MCR 2017 Feb;15(2):179-188
Primary cardiac diffuse large B-cell lymphoma in immunocompetent patients: clinical, histologic, immunophenotypic, and genotypic features of 3 cases.
Soon G, Ow GW, Chan HL, Ng SB, Wang S
Annals of diagnostic pathology 2016 Oct;24:40-6
Annals of diagnostic pathology 2016 Oct;24:40-6
In Utero Exposure to Valproic Acid Induces Neocortical Dysgenesis via Dysregulation of Neural Progenitor Cell Proliferation/Differentiation.
Fujimura K, Mitsuhashi T, Shibata S, Shimozato S, Takahashi T
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Oct 19;36(42):10908-10919
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Oct 19;36(42):10908-10919
Renal cell carcinoma in kidney allografts: histologic types, including biphasic papillary carcinoma.
Troxell ML, Higgins JP
Human pathology 2016 Nov;57:28-36
Human pathology 2016 Nov;57:28-36
Cyclin D1 expression in peripheral T-cell lymphomas.
Song JY, Song L, Herrera AF, Venkataraman G, Murata-Collins JL, Bedell VH, Chen YY, Kim YS, Tadros R, Nathwani BN, Weisenburger DD, Feldman AL
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 Nov;29(11):1306-1312
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 Nov;29(11):1306-1312
MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration.
Antony AN, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, Rubin E, Csordás G, Seifert EL, Hoek JB, Hajnóczky G
Nature communications 2016 Mar 9;7:10955
Nature communications 2016 Mar 9;7:10955
Arm Selection Preference of MicroRNA-193a Varies in Breast Cancer.
Tsai KW, Leung CM, Lo YH, Chen TW, Chan WC, Yu SY, Tu YT, Lam HC, Li SC, Ger LP, Liu WS, Chang HT
Scientific reports 2016 Jun 16;6:28176
Scientific reports 2016 Jun 16;6:28176
The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells.
Mayr C, Wagner A, Loeffelberger M, Bruckner D, Jakab M, Berr F, Di Fazio P, Ocker M, Neureiter D, Pichler M, Kiesslich T
Oncotarget 2016 Jan 5;7(1):745-58
Oncotarget 2016 Jan 5;7(1):745-58
Everolimus-induced epithelial to mesenchymal transition (EMT) in bronchial/pulmonary cells: when the dosage does matter in transplantation.
Tomei P, Masola V, Granata S, Bellin G, Carratù P, Ficial M, Ventura VA, Onisto M, Resta O, Gambaro G, Chilosi M, Lupo A, Zaza G
Journal of nephrology 2016 Dec;29(6):881-891
Journal of nephrology 2016 Dec;29(6):881-891
Overexpression of β-Catenin and Cyclin D1 is Associated with Poor Overall Survival in Patients with Stage IA-IIA Squamous Cell Lung Cancer Irrespective of Adjuvant Chemotherapy.
Kim Y, Jin D, Lee BB, Cho EY, Han J, Shim YM, Kim HK, Kim DH
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 Dec;11(12):2193-2201
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 Dec;11(12):2193-2201
Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages.
Doobin DJ, Kemal S, Dantas TJ, Vallee RB
Nature communications 2016 Aug 24;7:12551
Nature communications 2016 Aug 24;7:12551
Survivin and cycline D1 expressions are associated with malignant potential in mucinous ovarian neoplasms.
Kanter M, Turan G, Usta C, Usta A, Esen HH, Tavlı L, Celik C, Demirkol Y, Kanter B
Journal of molecular histology 2016 Apr;47(2):145-52
Journal of molecular histology 2016 Apr;47(2):145-52
Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.
Shain AH, Garrido M, Botton T, Talevich E, Yeh I, Sanborn JZ, Chung J, Wang NJ, Kakavand H, Mann GJ, Thompson JF, Wiesner T, Roy R, Olshen AB, Gagnon A, Gray JW, Huh N, Hur JS, Busam KJ, Scolyer RA, Cho RJ, Murali R, Bastian BC
Nature genetics 2015 Oct;47(10):1194-9
Nature genetics 2015 Oct;47(10):1194-9
Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome.
Chaudhary SC, Tang X, Arumugam A, Li C, Srivastava RK, Weng Z, Xu J, Zhang X, Kim AL, McKay K, Elmets CA, Kopelovich L, Bickers DR, Athar M
Oncotarget 2015 Nov 3;6(34):36789-814
Oncotarget 2015 Nov 3;6(34):36789-814
miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway.
van Jaarsveld MT, van Kuijk PF, Boersma AW, Helleman J, van IJcken WF, Mathijssen RH, Pothof J, Berns EM, Verweij J, Wiemer EA
Molecular cancer 2015 Nov 17;14:196
Molecular cancer 2015 Nov 17;14:196
Concurrent radiotherapy with gefitinib in elderly patients with esophageal squamous cell carcinoma: Preliminary results of a phase II study.
Xu Y, Zheng Y, Sun X, Yu X, Gu J, Wu W, Zhang G, Hu J, Sun W, Mao W
Oncotarget 2015 Nov 10;6(35):38429-39
Oncotarget 2015 Nov 10;6(35):38429-39
Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance.
Dabydeen SA, Kang K, Díaz-Cruz ES, Alamri A, Axelrod ML, Bouker KB, Al-Kharboosh R, Clarke R, Hennighausen L, Furth PA
Carcinogenesis 2015 Jan;36(1):122-32
Carcinogenesis 2015 Jan;36(1):122-32
Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex.
Wong FK, Fei JF, Mora-Bermúdez F, Taverna E, Haffner C, Fu J, Anastassiadis K, Stewart AF, Huttner WB
PLoS biology 2015 Aug;13(8):e1002217
PLoS biology 2015 Aug;13(8):e1002217
Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies.
Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt AW, Anderson S, Moskalev I, Haegert A, Alshalalfa M, Erho N, Davicioni E, Fazli L, Li E, Collins C, Wang Y, Black PC
Oncotarget 2015 Aug 28;6(25):21522-32
Oncotarget 2015 Aug 28;6(25):21522-32
Altered PPP2R2A and Cyclin D1 expression defines a subgroup of aggressive luminal-like breast cancer.
Beca F, Pereira M, Cameselle-Teijeiro JF, Martins D, Schmitt F
BMC cancer 2015 Apr 15;15:285
BMC cancer 2015 Apr 15;15:285
In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells.
Berkenkamp B, Susnik N, Baisantry A, Kuznetsova I, Jacobi C, Sörensen-Zender I, Broecker V, Haller H, Melk A, Schmitt R
PloS one 2014;9(2):e88071
PloS one 2014;9(2):e88071
The role of core needle biopsy in the preoperative diagnosis of follicular neoplasm of the thyroid.
Min HS, Kim JH, Ryoo I, Jung SL, Jung CK
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2014 Oct;122(10):993-1000
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2014 Oct;122(10):993-1000
Sequential immunohistochemistry: a promising new tool for the pathology laboratory.
van den Brand M, Hoevenaars BM, Sigmans JH, Meijer JW, van Cleef PH, Groenen PJ, Hebeda KM, van Krieken JH
Histopathology 2014 Nov;65(5):651-7
Histopathology 2014 Nov;65(5):651-7
Development of a conditionally immortalized human pancreatic β cell line.
Scharfmann R, Pechberty S, Hazhouz Y, von Bülow M, Bricout-Neveu E, Grenier-Godard M, Guez F, Rachdi L, Lohmann M, Czernichow P, Ravassard P
The Journal of clinical investigation 2014 May;124(5):2087-98
The Journal of clinical investigation 2014 May;124(5):2087-98
Immunohistochemical and FISH analysis of EGFR and its prognostic value in patients with oral squamous cell carcinoma.
Gröbe A, Eichhorn W, Fraederich M, Kluwe L, Vashist Y, Wikner J, Smeets R, Simon R, Sauter G, Heiland M, Blessmann M
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2014 Mar;43(3):205-10
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2014 Mar;43(3):205-10
Longer survival in patients with breast cancer with cyclin d1 over-expression after tumor recurrence: longer, but occupied with disease.
Chung J, Noh H, Park KH, Choi E, Han A
Journal of breast cancer 2014 Mar;17(1):47-53
Journal of breast cancer 2014 Mar;17(1):47-53
A growth-promoting signaling component cyclin D1 in neural stem cells has antiastrogliogenic function to execute self-renewal.
Bizen N, Inoue T, Shimizu T, Tabu K, Kagawa T, Taga T
Stem cells (Dayton, Ohio) 2014 Jun;32(6):1602-15
Stem cells (Dayton, Ohio) 2014 Jun;32(6):1602-15
Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes.
Tane S, Kubota M, Okayama H, Ikenishi A, Yoshitome S, Iwamoto N, Satoh Y, Kusakabe A, Ogawa S, Kanai A, Molkentin JD, Nakamura K, Ohbayashi T, Takeuchi T
The Journal of biological chemistry 2014 Jun 27;289(26):18033-44
The Journal of biological chemistry 2014 Jun 27;289(26):18033-44
The expression of apoptosis inducing factor (AIF) is associated with aging-related cell death in the cortex but not in the hippocampus in the TgCRND8 mouse model of Alzheimer's disease.
Yu W, Bonnet M, Farso M, Ma K, Chabot JG, Martin E, Torriglia A, Guan Z, McLaurin J, Quirion R, Krantic S
BMC neuroscience 2014 Jun 10;15:73
BMC neuroscience 2014 Jun 10;15:73
Immunohistochemistry-based subtyping of breast carcinoma in Egyptian women: a clinicopathologic study on 125 patients.
Elesawy BH, Abd El hafez A, Shawky Ael-A, Arafa M
Annals of diagnostic pathology 2014 Feb;18(1):21-6
Annals of diagnostic pathology 2014 Feb;18(1):21-6
Well-differentiated follicular patterned tumors of the thyroid with high-grade features can metastasize in the absence of capsular or vascular invasion: report of a case.
Bongiovanni M, Mazzucchelli L, Giovanella L, Frattini M, Pusztaszeri M
International journal of surgical pathology 2014 Dec;22(8):749-56
International journal of surgical pathology 2014 Dec;22(8):749-56
4EGI-1 targets breast cancer stem cells by selective inhibition of translation that persists in CSC maintenance, proliferation and metastasis.
Yi T, Kabha E, Papadopoulos E, Wagner G
Oncotarget 2014 Aug 15;5(15):6028-37
Oncotarget 2014 Aug 15;5(15):6028-37
A tissue quality index: an intrinsic control for measurement of effects of preanalytical variables on FFPE tissue.
Neumeister VM, Parisi F, England AM, Siddiqui S, Anagnostou V, Zarrella E, Vassilakopolou M, Bai Y, Saylor S, Sapino A, Kluger Y, Hicks DG, Bussolati G, Kwei S, Rimm DL
Laboratory investigation; a journal of technical methods and pathology 2014 Apr;94(4):467-74
Laboratory investigation; a journal of technical methods and pathology 2014 Apr;94(4):467-74
Chromosome instability predicts progression of premalignant lesions of the larynx.
Bergshoeff VE, Van der Heijden SJ, Haesevoets A, Litjens SG, Bot FJ, Voogd AC, Chenault MN, Hopman AH, Schuuring E, Van der Wal JM, Manni JJ, Ramaekers FC, Kremer B, Speel EJ
Pathology 2014 Apr;46(3):216-24
Pathology 2014 Apr;46(3):216-24
Expression Profiling of Proliferation and Apoptotic Markers along the Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis Patients.
Wang J, El-Masry N, Talbot I, Tomlinson I, Alison MR, El-Bahrawy M
Gastroenterology research and practice 2013;2013:107534
Gastroenterology research and practice 2013;2013:107534
Cyclin D1 is required for proliferation of Olig2-expressing progenitor cells in the injured cerebral cortex.
Nobs L, Nestel S, Kulik A, Nitsch C, Atanasoski S
Glia 2013 Sep;61(9):1443-55
Glia 2013 Sep;61(9):1443-55
The THO ribonucleoprotein complex is required for stem cell homeostasis in the adult mouse small intestine.
Pitzonka L, Wang X, Ullas S, Wolff DW, Wang Y, Goodrich DW
Molecular and cellular biology 2013 Sep;33(17):3505-14
Molecular and cellular biology 2013 Sep;33(17):3505-14
Florid lobular carcinoma in situ: molecular profiling and comparison to classic lobular carcinoma in situ and pleomorphic lobular carcinoma in situ.
Shin SJ, Lal A, De Vries S, Suzuki J, Roy R, Hwang ES, Schnitt SJ, Waldman FM, Chen YY
Human pathology 2013 Oct;44(10):1998-2009
Human pathology 2013 Oct;44(10):1998-2009
The impact of molecular morphology techniques on the expert diagnosis in melanocytic skin neoplasms.
Ferrara G, Misciali C, Brenn T, Cerroni L, Kazakov DW, Perasole A, Russo R, Ricci R, Crisman G, Fanti PA, Passarini B, Patrizi A
International journal of surgical pathology 2013 Oct;21(5):483-92
International journal of surgical pathology 2013 Oct;21(5):483-92
Cooperation between Dmp1 loss and cyclin D1 overexpression in breast cancer.
Zhu S, Mott RT, Fry EA, Taneja P, Kulik G, Sui G, Inoue K
The American journal of pathology 2013 Oct;183(4):1339-1350
The American journal of pathology 2013 Oct;183(4):1339-1350
The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit.
Spencer SL, Cappell SD, Tsai FC, Overton KW, Wang CL, Meyer T
Cell 2013 Oct 10;155(2):369-83
Cell 2013 Oct 10;155(2):369-83
Identification of novel target proteins in sebaceous gland carcinoma.
Erovic BM, Al Habeeb A, Harris L, Goldstein DP, Kim D, Ghazarian D, Irish JC
Head & neck 2013 May;35(5):642-8
Head & neck 2013 May;35(5):642-8
Regional differences in gallbladder cancer pathogenesis: insights from a comparison of cell cycle-regulatory, PI3K, and pro-angiogenic protein expression.
Butte JM, Torres J, Veras EF, Matsuo K, Gönen M, D'Angelica MI, Waugh E, Meneses M, Inayama Y, Fong Y, Dematteo RP, De La Fuente H, Endo I, Klimstra DS, Jarnagin WR
Annals of surgical oncology 2013 May;20(5):1470-81
Annals of surgical oncology 2013 May;20(5):1470-81
SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity.
Noah TK, Lo YH, Price A, Chen G, King E, Washington MK, Aronow BJ, Shroyer NF
Gastroenterology 2013 May;144(5):1012-1023.e6
Gastroenterology 2013 May;144(5):1012-1023.e6
Immunohistochemical analysis of the expression of MAGE-A and NY-ESO-1 cancer/testis antigens in diffuse large B-cell testicular lymphoma.
Hudolin T, Kastelan Z, Ilic I, Levarda-Hudolin K, Basic-Jukic N, Rieken M, Spagnoli GC, Juretic A, Mengus C
Journal of translational medicine 2013 May 16;11:123
Journal of translational medicine 2013 May 16;11:123
Diffuse large B-cell lymphoma of the ocular adnexal region: a nation-based study.
Rasmussen PK, Ralfkiaer E, Prause JU, Sjö LD, Toft PB, Siersma VD, Heegaard S
Acta ophthalmologica 2013 Mar;91(2):163-9
Acta ophthalmologica 2013 Mar;91(2):163-9
The PPARγ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency.
Nakles RE, Kallakury BV, Furth PA
The American journal of pathology 2013 Jun;182(6):1976-85
The American journal of pathology 2013 Jun;182(6):1976-85
Diffuse large B-cell lymphoma and mantle cell lymphoma of the ocular adnexal region, and lymphoma of the lacrimal gland: an investigation of clinical and histopathological features.
Rasmussen PK
Acta ophthalmologica 2013 Jul;91 Thesis 5:1-27
Acta ophthalmologica 2013 Jul;91 Thesis 5:1-27
Clonally related follicular lymphomas and Langerhans cell neoplasms: expanding the spectrum of transdifferentiation.
West DS, Dogan A, Quint PS, Tricker-Klar ML, Porcher JC, Ketterling RP, Law ME, McPhail ED, Viswanatha DS, Kurtin PJ, Dao LN, Ritzer RD, Nowakowski GS, Feldman AL
The American journal of surgical pathology 2013 Jul;37(7):978-86
The American journal of surgical pathology 2013 Jul;37(7):978-86
Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a clinicopathologic and molecular study.
Hoeller S, Zhou Y, Kanagal-Shamanna R, Xu-Monette ZY, Hoehn D, Bihl M, Swerdlow SH, Rosenwald A, Ott G, Said J, Dunphy CH, Bueso-Ramos CE, Lin P, Wang M, Miranda RN, Tzankov A, Medeiros LJ, Young KH
Human pathology 2013 Jan;44(1):110-21
Human pathology 2013 Jan;44(1):110-21
Plant stanols induce intestinal tumor formation by up-regulating Wnt and EGFR signaling in Apc Min mice.
Marttinen M, Päivärinta E, Storvik M, Huikko L, Luoma-Halkola H, Piironen V, Pajari AM, Mutanen M
The Journal of nutritional biochemistry 2013 Jan;24(1):343-52
The Journal of nutritional biochemistry 2013 Jan;24(1):343-52
Correct timing of proliferation and differentiation is necessary for normal inner ear development and auditory hair cell viability.
Kopecky BJ, Jahan I, Fritzsch B
Developmental dynamics : an official publication of the American Association of Anatomists 2013 Feb;242(2):132-47
Developmental dynamics : an official publication of the American Association of Anatomists 2013 Feb;242(2):132-47
MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism.
Alvelos MI, Vinagre J, Fonseca E, Barbosa E, Teixeira-Gomes J, Sobrinho-Simões M, Soares P
European journal of endocrinology 2013 Feb;168(2):119-28
European journal of endocrinology 2013 Feb;168(2):119-28
Clonally related composite follicular lymphoma and mantle cell lymphoma with clinicopathologic features and biological implications.
Wang S, Tzankov A, Xu-Monette ZY, Hoeller S, Wang SA, Richards KL, Zhang S, Said JW, Medeiros LJ, Young KH
Human pathology 2013 Dec;44(12):2658-67
Human pathology 2013 Dec;44(12):2658-67
A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.
Pribluda A, Elyada E, Wiener Z, Hamza H, Goldstein RE, Biton M, Burstain I, Morgenstern Y, Brachya G, Billauer H, Biton S, Snir-Alkalay I, Vucic D, Schlereth K, Mernberger M, Stiewe T, Oren M, Alitalo K, Pikarsky E, Ben-Neriah Y
Cancer cell 2013 Aug 12;24(2):242-56
Cancer cell 2013 Aug 12;24(2):242-56
The CDKN2A and MAP kinase pathways: molecular roads to primary oral mucosal melanoma.
Hsieh R, Nico MM, Coutinho-Camillo CM, Buim ME, Sangueza M, Lourenço SV
The American Journal of dermatopathology 2013 Apr;35(2):167-75
The American Journal of dermatopathology 2013 Apr;35(2):167-75
VR09 cell line: an EBV-positive lymphoblastoid cell line with in vivo characteristics of diffuse large B cell lymphoma of activated B-cell type.
Nichele I, Zamò A, Bertolaso A, Bifari F, Tinelli M, Franchini M, Stradoni R, Aprili F, Pizzolo G, Krampera M
PloS one 2012;7(12):e52811
PloS one 2012;7(12):e52811
COUP-TFII controls mouse pancreatic β-cell mass through GLP-1-β-catenin signaling pathways.
Boutant M, Ramos OH, Tourrel-Cuzin C, Movassat J, Ilias A, Vallois D, Planchais J, Pégorier JP, Schuit F, Petit PX, Bossard P, Maedler K, Grapin-Botton A, Vasseur-Cognet M
PloS one 2012;7(1):e30847
PloS one 2012;7(1):e30847
Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood.
Anttonen T, Kirjavainen A, Belevich I, Laos M, Richardson WD, Jokitalo E, Brakebusch C, Pirvola U
Scientific reports 2012;2:978
Scientific reports 2012;2:978
Cyclin D1 overexpression associates with favourable prognostic factors in invasive breast carcinoma.
El-Hafez AA, El Aaty Shawky A, Hasan B
Cancer biomarkers : section A of Disease markers 2012;12(4):149-54
Cancer biomarkers : section A of Disease markers 2012;12(4):149-54
Cyclin D1 induction preceding neuronal death via the excitotoxic NMDA pathway involves selective stimulation of extrasynaptic NMDA receptors and JNK pathway.
Efthimiadi L, Farso M, Quirion R, Krantic S
Neuro-degenerative diseases 2012;10(1-4):80-91
Neuro-degenerative diseases 2012;10(1-4):80-91
SMARCB1/INI1 inactivation in renal medullary carcinoma.
Calderaro J, Moroch J, Pierron G, Pedeutour F, Grison C, Maillé P, Soyeux P, de la Taille A, Couturier J, Vieillefond A, Rousselet MC, Delattre O, Allory Y
Histopathology 2012 Sep;61(3):428-35
Histopathology 2012 Sep;61(3):428-35
CD5-positive mucosa-associated lymphoid tissue (MALT) lymphoma: a clinicopathologic study of 14 cases.
Jaso J, Chen L, Li S, Lin P, Chen W, Miranda RN, Konoplev S, Medeiros LJ, Yin CC
Human pathology 2012 Sep;43(9):1436-43
Human pathology 2012 Sep;43(9):1436-43
Attenuation of the retinoblastoma pathway in pancreatic neuroendocrine tumors due to increased cdk4/cdk6.
Tang LH, Contractor T, Clausen R, Klimstra DS, Du YC, Allen PJ, Brennan MF, Levine AJ, Harris CR
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Sep 1;18(17):4612-20
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Sep 1;18(17):4612-20
Cell cycle regulation in mouse heart during embryonic and postnatal stages.
Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, Obayashi T, Hayashi T, Takeuchi T
Development, growth & differentiation 2012 Oct;54(8):731-8
Development, growth & differentiation 2012 Oct;54(8):731-8
Genetic characterization of mesenchymal, clear cell, and dedifferentiated chondrosarcoma.
Meijer D, de Jong D, Pansuriya TC, van den Akker BE, Picci P, Szuhai K, Bovée JV
Genes, chromosomes & cancer 2012 Oct;51(10):899-909
Genes, chromosomes & cancer 2012 Oct;51(10):899-909
Fibrin-associated large B-cell lymphoma: part of the spectrum of cardiac lymphomas.
Gruver AM, Huba MA, Dogan A, Hsi ED
The American journal of surgical pathology 2012 Oct;36(10):1527-37
The American journal of surgical pathology 2012 Oct;36(10):1527-37
UM-SCC-104: a new human papillomavirus-16-positive cancer stem cell-containing head and neck squamous cell carcinoma cell line.
Tang AL, Hauff SJ, Owen JH, Graham MP, Czerwinski MJ, Park JJ, Walline H, Papagerakis S, Stoerker J, McHugh JB, Chepeha DB, Bradford CR, Carey TE, Prince ME
Head & neck 2012 Oct;34(10):1480-91
Head & neck 2012 Oct;34(10):1480-91
Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres.
Virolainen SM, Achim K, Peltopuro P, Salminen M, Partanen J
Development (Cambridge, England) 2012 Oct;139(20):3795-805
Development (Cambridge, England) 2012 Oct;139(20):3795-805
Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer.
Myklebust MP, Li Z, Tran TH, Rui H, Knudsen ES, Elsaleh H, Fluge Ø, Vonen B, Myrvold HE, Leh S, Tveit KM, Pestell RG, Dahl O
British journal of cancer 2012 Nov 6;107(10):1684-91
British journal of cancer 2012 Nov 6;107(10):1684-91
The 3-layered ductal epithelium in gynecomastia.
Kornegoor R, Verschuur-Maes AH, Buerger H, van Diest PJ
The American journal of surgical pathology 2012 May;36(5):762-8
The American journal of surgical pathology 2012 May;36(5):762-8
Prognostic role of SOX11 in a population-based cohort of mantle cell lymphoma.
Nygren L, Baumgartner Wennerholm S, Klimkowska M, Christensson B, Kimby E, Sander B
Blood 2012 May 3;119(18):4215-23
Blood 2012 May 3;119(18):4215-23
Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis.
Lax S, Schauer G, Prein K, Kapitan M, Silbert D, Berghold A, Berger A, Trauner M
International journal of cancer 2012 May 15;130(10):2232-9
International journal of cancer 2012 May 15;130(10):2232-9
Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development.
Le TT, Conley KW, Mead TJ, Rowan S, Yutzey KE, Brown NL
Developmental dynamics : an official publication of the American Association of Anatomists 2012 Mar;241(3):493-504
Developmental dynamics : an official publication of the American Association of Anatomists 2012 Mar;241(3):493-504
EBV+ diffuse large B-cell lymphoma arising within atrial myxoma. An example of a distinct primary cardiac EBV+ DLBCL of immunocompetent patients.
Svec A, Rangaiah M, Giles M, Jaksa R, McAulay KA
Pathology, research and practice 2012 Mar 15;208(3):172-6
Pathology, research and practice 2012 Mar 15;208(3):172-6
Endometrial tumorigenesis in Pten(+/-) mice is independent of coexistence of estrogen and estrogen receptor α.
Joshi A, Wang H, Jiang G, Douglas W, Chan JS, Korach KS, Ellenson LH
The American journal of pathology 2012 Jun;180(6):2536-47
The American journal of pathology 2012 Jun;180(6):2536-47
Cyclin D1 and FADD as biomarkers in head and neck squamous cell carcinoma.
Rasamny JJ, Allak A, Krook KA, Jo VY, Policarpio-Nicolas ML, Sumner HM, Moskaluk CA, Frierson HF Jr, Jameson MJ
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2012 Jun;146(6):923-31
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2012 Jun;146(6):923-31
γ-Tocotrienol inhibits cell viability through suppression of β-catenin/Tcf signaling in human colon carcinoma HT-29 cells.
Xu W, Du M, Zhao Y, Wang Q, Sun W, Chen B
The Journal of nutritional biochemistry 2012 Jul;23(7):800-7
The Journal of nutritional biochemistry 2012 Jul;23(7):800-7
FADD expression as a prognosticator in early-stage glottic squamous cell carcinoma of the larynx treated primarily with radiotherapy.
Schrijvers ML, Pattje WJ, Slagter-Menkema L, Mastik MF, Gibcus JH, Langendijk JA, van der Wal JE, van der Laan BF, Schuuring E
International journal of radiation oncology, biology, physics 2012 Jul 15;83(4):1220-6
International journal of radiation oncology, biology, physics 2012 Jul 15;83(4):1220-6
Early changes in carcinogenesis of colorectal adenomas.
Toru S, Bilezikçi B
The West Indian medical journal 2012 Jan;61(1):10-6
The West Indian medical journal 2012 Jan;61(1):10-6
Early changes in carcinogenesis of colorectal adenomas.
Toru S, Bilezikçi B
The West Indian medical journal 2012 Jan;61(1):10-6
The West Indian medical journal 2012 Jan;61(1):10-6
Evaluation of immunohistochemical expression of p53, p21, p27, cyclin D1, and Ki67 in oral and oropharyngeal squamous cell carcinoma.
Perisanidis C, Perisanidis B, Wrba F, Brandstetter A, El Gazzar S, Papadogeorgakis N, Seemann R, Ewers R, Kyzas PA, Filipits M
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2012 Jan;41(1):40-6
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2012 Jan;41(1):40-6
Alteration of G1/S transition regulators influences recurrences in head and neck squamous carcinomas.
Canzonieri V, Barzan L, Franchin G, Vaccher E, Talamini R, Sulfaro S, Baldassarre G
Journal of cellular physiology 2012 Jan;227(1):233-8
Journal of cellular physiology 2012 Jan;227(1):233-8
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Moustafa T, Fickert P, Magnes C, Guelly C, Thueringer A, Frank S, Kratky D, Sattler W, Reicher H, Sinner F, Gumhold J, Silbert D, Fauler G, Höfler G, Lass A, Zechner R, Trauner M
Gastroenterology 2012 Jan;142(1):140-151.e12
Gastroenterology 2012 Jan;142(1):140-151.e12
Routine pathologic parameters can predict Oncotype DX recurrence scores in subsets of ER positive patients: who does not always need testing?
Allison KH, Kandalaft PL, Sitlani CM, Dintzis SM, Gown AM
Breast cancer research and treatment 2012 Jan;131(2):413-24
Breast cancer research and treatment 2012 Jan;131(2):413-24
A rare S33C mutation of CTNNB1 encoding β-catenin in a parathyroid adenoma found in an Italian primary hyperparathyroid cohort.
Guarnieri V, Baorda F, Battista C, Bisceglia M, Balsamo T, Gruppioni E, Fiorentino M, Muscarella LA, Coco M, Barbano R, Corbetta S, Spada A, Cole DE, Canaff L, Hendy GN, Carella M, Scillitani A
Endocrine 2012 Feb;41(1):152-5
Endocrine 2012 Feb;41(1):152-5
Reduced chondrocyte proliferation, earlier cell cycle exit and increased apoptosis in neuronal nitric oxide synthase-deficient mice.
Yan Q, Feng Q, Beier F
Osteoarthritis and cartilage 2012 Feb;20(2):144-51
Osteoarthritis and cartilage 2012 Feb;20(2):144-51
FOXA1 promotes tumor progression in prostate cancer and represents a novel hallmark of castration-resistant prostate cancer.
Gerhardt J, Montani M, Wild P, Beer M, Huber F, Hermanns T, Müntener M, Kristiansen G
The American journal of pathology 2012 Feb;180(2):848-61
The American journal of pathology 2012 Feb;180(2):848-61
Cyclin D1 overexpression and poor clinical outcomes in Taiwanese oral cavity squamous cell carcinoma.
Huang SF, Cheng SD, Chuang WY, Chen IH, Liao CT, Wang HM, Hsieh LL
World journal of surgical oncology 2012 Feb 16;10:40
World journal of surgical oncology 2012 Feb 16;10:40
Immunophenotyping of male breast cancer.
Kornegoor R, Verschuur-Maes AH, Buerger H, Hogenes MC, de Bruin PC, Oudejans JJ, Hinrichs B, van Diest PJ
Histopathology 2012 Dec;61(6):1145-55
Histopathology 2012 Dec;61(6):1145-55
Cyclin D1, E-cadherin and beta-catenin expression in FIGO Stage IA cervical squamous carcinoma: diagnostic value and evidence for epithelial-mesenchymal transition.
Koay MH, Crook M, Stewart CJ
Histopathology 2012 Dec;61(6):1125-33
Histopathology 2012 Dec;61(6):1125-33
Prognostic and predictive markers in medullary thyroid carcinoma.
Erovic BM, Kim D, Cassol C, Goldstein DP, Irish JC, Asa SL, Mete O
Endocrine pathology 2012 Dec;23(4):232-42
Endocrine pathology 2012 Dec;23(4):232-42
Biomarkers of parathyroid carcinoma.
Erovic BM, Harris L, Jamali M, Goldstein DP, Irish JC, Asa SL, Mete O
Endocrine pathology 2012 Dec;23(4):221-31
Endocrine pathology 2012 Dec;23(4):221-31
Quantitative assessment of effect of preanalytic cold ischemic time on protein expression in breast cancer tissues.
Neumeister VM, Anagnostou V, Siddiqui S, England AM, Zarrella ER, Vassilakopoulou M, Parisi F, Kluger Y, Hicks DG, Rimm DL
Journal of the National Cancer Institute 2012 Dec 5;104(23):1815-24
Journal of the National Cancer Institute 2012 Dec 5;104(23):1815-24
Pulmonary involvement by chronic lymphocytic leukemia/small lymphocytic lymphoma is a specific pathologic finding independent of inflammatory infiltration.
Hill BT, Weil AC, Kalaycio M, Cook JR
Leukemia & lymphoma 2012 Apr;53(4):589-95
Leukemia & lymphoma 2012 Apr;53(4):589-95
Identification of prognostic biomarkers for glioblastomas using protein expression profiling.
Jung Y, Joo KM, Seong DH, Choi YL, Kong DS, Kim Y, Kim MH, Jin J, Suh YL, Seol HJ, Shin CS, Lee JI, Kim JH, Song SY, Nam DH
International journal of oncology 2012 Apr;40(4):1122-32
International journal of oncology 2012 Apr;40(4):1122-32
Restrictions in cell cycle progression of adult vestibular supporting cells in response to ectopic cyclin D1 expression.
Loponen H, Ylikoski J, Albrecht JH, Pirvola U
PloS one 2011;6(11):e27360
PloS one 2011;6(11):e27360
Transgenic expression of entire hepatitis B virus in mice induces hepatocarcinogenesis independent of chronic liver injury.
Na B, Huang Z, Wang Q, Qi Z, Tian Y, Lu CC, Yu J, Hanes MA, Kakar S, Huang EJ, Ou JH, Liu L, Yen TS
PloS one 2011;6(10):e26240
PloS one 2011;6(10):e26240
Comparative analysis of biological profiles of benign prostate hyperplasia and prostate cancer as potential diagnostic, prognostic and predictive indicators.
Makarewicz R, Zyromska A, Andrusewicz H
Folia histochemica et cytobiologica 2011;49(3):452-7
Folia histochemica et cytobiologica 2011;49(3):452-7
Translocation (5; 11) in a conjunctival MALT lymphoma.
Clement CG, Potluri VR, Gonzales J, Qian YW
International journal of clinical and experimental pathology 2011;4(7):722-6
International journal of clinical and experimental pathology 2011;4(7):722-6
Delineation of chondroid lipoma: an immunohistochemical and molecular biological analysis.
de Vreeze RS, van Coevorden F, Boerrigter L, Nederlof PM, Haas RL, Bras J, Rosenwald A, Mentzel T, de Jong D
Sarcoma 2011;2011:638403
Sarcoma 2011;2011:638403
An assessment of the usefulness of immunohistochemical stains in the diagnosis of hairy cell leukemia.
Sherman MJ, Hanson CA, Hoyer JD
American journal of clinical pathology 2011 Sep;136(3):390-9
American journal of clinical pathology 2011 Sep;136(3):390-9
Small cell variant of mantle cell lymphoma is an indolent lymphoma characterized by bone marrow involvement, splenomegaly, and a low Ki-67 index.
Kimura Y, Sato K, Imamura Y, Arakawa F, Kiyasu J, Takeuchi M, Miyoshi H, Yoshida M, Niino D, Sugita Y, Morito T, Yoshino T, Nakamura S, Ohshima K
Cancer science 2011 Sep;102(9):1734-41
Cancer science 2011 Sep;102(9):1734-41
Inducible nitric oxide synthase-nitric oxide signaling mediates the mitogenic activity of Rac1 during endochondral bone growth.
Wang G, Yan Q, Woods A, Aubrey LA, Feng Q, Beier F
Journal of cell science 2011 Oct 15;124(Pt 20):3405-13
Journal of cell science 2011 Oct 15;124(Pt 20):3405-13
Expression of CD19 and lack of miR-223 distinguish extramedullary plasmacytoma from multiple myeloma.
Yu SC, Chen SU, Lu W, Liu TY, Lin CW
Histopathology 2011 May;58(6):896-905
Histopathology 2011 May;58(6):896-905
Acute sensitivity of the oral mucosa to oncogenic K-ras.
van der Weyden L, Alcolea MP, Jones PH, Rust AG, Arends MJ, Adams DJ
The Journal of pathology 2011 May;224(1):22-32
The Journal of pathology 2011 May;224(1):22-32
Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features.
Huh YO, Schweighofer CD, Ketterling RP, Knudson RA, Vega F, Kim JE, Luthra R, Keating MJ, Medeiros LJ, Abruzzo LV
American journal of clinical pathology 2011 May;135(5):686-96
American journal of clinical pathology 2011 May;135(5):686-96
FHL2 exhibits anti-proliferative and anti-apoptotic activities in liver cancer cells.
Ng CF, Ng PK, Lui VW, Li J, Chan JY, Fung KP, Ng YK, Lai PB, Tsui SK
Cancer letters 2011 May 28;304(2):97-106
Cancer letters 2011 May 28;304(2):97-106
Protein kinase Cα signaling regulates inhibitor of DNA binding 1 in the intestinal epithelium.
Hao F, Pysz MA, Curry KJ, Haas KN, Seedhouse SJ, Black AR, Black JD
The Journal of biological chemistry 2011 May 20;286(20):18104-17
The Journal of biological chemistry 2011 May 20;286(20):18104-17
TNFR2 interposes the proliferative and NF-κB-mediated inflammatory response by podocytes to TNF-α.
Bruggeman LA, Drawz PE, Kahoud N, Lin K, Barisoni L, Nelson PJ
Laboratory investigation; a journal of technical methods and pathology 2011 Mar;91(3):413-25
Laboratory investigation; a journal of technical methods and pathology 2011 Mar;91(3):413-25
Cyclin D1 positive diffuse large B-cell lymphoma is a post-germinal center-type lymphoma without alterations in the CCND1 gene locus.
Vela-Chávez T, Adam P, Kremer M, Bink K, Bacon CM, Menon G, Ferry JA, Fend F, Jaffe ES, Quintanilla-Martínez L
Leukemia & lymphoma 2011 Mar;52(3):458-66
Leukemia & lymphoma 2011 Mar;52(3):458-66
The Forkhead factor FoxQ1 influences epithelial differentiation.
Feuerborn A, Srivastava PK, Küffer S, Grandy WA, Sijmonsma TP, Gretz N, Brors B, Gröne HJ
Journal of cellular physiology 2011 Mar;226(3):710-9
Journal of cellular physiology 2011 Mar;226(3):710-9
Altered expression of cell-cell adhesion molecules β-catenin/E-cadherin and related Wnt-signaling pathway in sporadic and syndromal keratocystic odontogenic tumors.
Hakim SG, Kosmehl H, Sieg P, Trenkle T, Jacobsen HC, Attila Benedek G, Ribbat J, Driemel O
Clinical oral investigations 2011 Jun;15(3):321-8
Clinical oral investigations 2011 Jun;15(3):321-8
The transforming growth factor-α and cyclin D1 genes are direct targets of β-catenin signaling in hepatocyte proliferation.
Torre C, Benhamouche S, Mitchell C, Godard C, Veber P, Letourneur F, Cagnard N, Jacques S, Finzi L, Perret C, Colnot S
Journal of hepatology 2011 Jul;55(1):86-95
Journal of hepatology 2011 Jul;55(1):86-95
Photodynamic therapy reduces the histological features of actinic damage and the expression of early oncogenic markers.
Bagazgoitia L, Cuevas Santos J, Juarranz A, Jaén P
The British journal of dermatology 2011 Jul;165(1):144-51
The British journal of dermatology 2011 Jul;165(1):144-51
Expression and localization of E-cadherin and β-catenin in uterine carcinosarcoma.
Nishimura I, Ohishi Y, Oda Y, Kishimoto J, Yasunaga M, Okuma E, Kobayashi H, Wake N, Tsuneyoshi M
Virchows Archiv : an international journal of pathology 2011 Jan;458(1):85-94
Virchows Archiv : an international journal of pathology 2011 Jan;458(1):85-94
APRIL promotes cell-cycle progression in primary multiple myeloma cells: influence of D-type cyclin group and translocation status.
Quinn J, Glassford J, Percy L, Munson P, Marafioti T, Rodriguez-Justo M, Yong K
Blood 2011 Jan 20;117(3):890-901
Blood 2011 Jan 20;117(3):890-901
Molecular characteristics of mantle cell lymphoma presenting with clonal plasma cell component.
Visco C, Hoeller S, Malik JT, Xu-Monette ZY, Wiggins ML, Liu J, Sanger WG, Liu Z, Chang J, Ranheim EA, Gradowski JF, Serrano S, Wang HY, Liu Q, Dave S, Olsen B, Gascoyne RD, Campo E, Swerdlow SH, Chan WC, Tzankov A, Young KH
The American journal of surgical pathology 2011 Feb;35(2):177-89
The American journal of surgical pathology 2011 Feb;35(2):177-89
Epithelioid/mixed phenotype in gastrointestinal stromal tumors with KIT mutation from the stomach is associated with accelerated passage of late phases of the cell cycle and shorter disease-free survival.
Haller F, Cortis J, Helfrich J, Cameron S, Schüler P, Schwager S, Gunawan B, Füzesi L, Agaimy A
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011 Feb;24(2):248-55
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011 Feb;24(2):248-55
Effects of long-term storage on the detection of proteins, DNA, and mRNA in tissue microarray slides.
Karlsson C, Karlsson MG
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2011 Dec;59(12):1113-21
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2011 Dec;59(12):1113-21
Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells.
Lui VW, Lau CP, Ho K, Ng MH, Cheng SH, Tsao SW, Tsang CM, Lei KI, Chan AT, Mok TS
Investigational new drugs 2011 Dec;29(6):1241-52
Investigational new drugs 2011 Dec;29(6):1241-52
CK5/6, EGFR, Ki-67, cyclin D1, and nm23-H1 protein expressions as predictors of pathological complete response to neoadjuvant chemotherapy in triple-negative breast cancer patients.
Li XR, Liu M, Zhang YJ, Wang JD, Zheng YQ, Li J, Ma B, Song X
Medical oncology (Northwood, London, England) 2011 Dec;28 Suppl 1:S129-34
Medical oncology (Northwood, London, England) 2011 Dec;28 Suppl 1:S129-34
Flow cytometry as an accurate tool to complement fine needle aspiration cytology in the diagnosis of low grade malignant lymphomas.
Schmid S, Tinguely M, Cione P, Moch H, Bode B
Cytopathology : official journal of the British Society for Clinical Cytology 2011 Dec;22(6):397-406
Cytopathology : official journal of the British Society for Clinical Cytology 2011 Dec;22(6):397-406
Extraosseous (extramedullary) plasmacytomas: a clinicopathologic and immunophenotypic study of 32 Chinese cases.
Zuo Z, Tang Y, Bi CF, Zhang WY, Zhao S, Wang XQ, Yang QP, Zou LQ, Liu WP
Diagnostic pathology 2011 Dec 19;6:123
Diagnostic pathology 2011 Dec 19;6:123
An inexpensive method of small paraffin tissue microarrays using mechanical pencil tips.
Shebl AM, Zalata KR, Amin MM, El-Hawary AK
Diagnostic pathology 2011 Dec 1;6:117
Diagnostic pathology 2011 Dec 1;6:117
CD5(-) diffuse large B-cell lymphoma with peculiar cyclin D1+ phenotype. Pathologic and molecular characterization of a single case.
Lucioni M, Novara F, Riboni R, Fiandrino G, Nicola M, Kindl S, Boveri E, Jemos V, Arcaini L, Zuffardi O, Paulli M
Human pathology 2011 Aug;42(8):1204-8
Human pathology 2011 Aug;42(8):1204-8
Aberrant Wnt1/β-catenin expression is an independent poor prognostic marker of non-small cell lung cancer after surgery.
Xu X, Sun PL, Li JZ, Jheon S, Lee CT, Chung JH
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011 Apr;6(4):716-24
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011 Apr;6(4):716-24
High-level cytoplasmic cyclin D1 expression in lymph node metastases from prostate cancer independently predicts early biochemical failure and death in surgically treated patients.
Fleischmann A, Rocha C, Saxer-Sekulic N, Zlobec I, Sauter G, Thalmann GN
Histopathology 2011 Apr;58(5):781-9
Histopathology 2011 Apr;58(5):781-9
Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling.
Pighi C, Gu TL, Dalai I, Barbi S, Parolini C, Bertolaso A, Pedron S, Parisi A, Ren J, Cecconi D, Chilosi M, Menestrina F, Zamò A
Cellular oncology (Dordrecht) 2011 Apr;34(2):141-53
Cellular oncology (Dordrecht) 2011 Apr;34(2):141-53
Primary follicular lymphoma of the duodenum is a distinct mucosal/submucosal variant of follicular lymphoma: a retrospective study of 63 cases.
Schmatz AI, Streubel B, Kretschmer-Chott E, Püspök A, Jäger U, Mannhalter C, Tiemann M, Ott G, Fischbach W, Herzog P, Seitz G, Stolte M, Raderer M, Chott A
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Apr 10;29(11):1445-51
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Apr 10;29(11):1445-51
Use of cyclin D1 in conjunction with human papillomavirus status to predict outcome in oropharyngeal cancer.
Hong AM, Dobbins TA, Lee CS, Jones D, Fei J, Clark JR, Armstrong BK, Harnett GB, Milross CG, Tran N, Peculis LD, Ng C, Milne AG, Loo C, Hughes LJ, Forstner DF, O'Brien CJ, Rose BR
International journal of cancer 2011 Apr 1;128(7):1532-45
International journal of cancer 2011 Apr 1;128(7):1532-45
Pediatric lymphomas in Brazil.
Gualco G, Klumb CE, Barber GN, Weiss LM, Bacchi CE
Clinics (Sao Paulo, Brazil) 2010;65(12):1267-77
Clinics (Sao Paulo, Brazil) 2010;65(12):1267-77
Pediatric lymphomas in Brazil.
Gualco G, Klumb CE, Barber GN, Weiss LM, Bacchi CE
Clinics (Sao Paulo, Brazil) 2010;65(12):1267-77
Clinics (Sao Paulo, Brazil) 2010;65(12):1267-77
Unique patterns of tumor growth related with the risk of lymph node metastasis in papillary thyroid carcinoma.
Jung CK, Kang YG, Bae JS, Lim DJ, Choi YJ, Lee KY
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010 Sep;23(9):1201-8
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010 Sep;23(9):1201-8
Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis.
Lee G, Goretsky T, Managlia E, Dirisina R, Singh AP, Brown JB, May R, Yang GY, Ragheb JW, Evers BM, Weber CR, Turner JR, He XC, Katzman RB, Li L, Barrett TA
Gastroenterology 2010 Sep;139(3):869-81, 881.e1-9
Gastroenterology 2010 Sep;139(3):869-81, 881.e1-9
Acute dyspnoea and single tracheal localisation of mantle cell lymphoma.
Ianotto JC, Tempescul A, Eveillard JR, André N, Morel F, Quintin-Roué I, Berthou C
Journal of hematology & oncology 2010 Sep 28;3:34
Journal of hematology & oncology 2010 Sep 28;3:34
Immunohistochemical comparative study of the odontogenic keratocysts and other odontogenic lesions.
de Vicente JC, Torre-Iturraspe A, Gutiérrez AM, Lequerica-Fernández P
Medicina oral, patologia oral y cirugia bucal 2010 Sep 1;15(5):e709-15
Medicina oral, patologia oral y cirugia bucal 2010 Sep 1;15(5):e709-15
Immunohistochemical comparative study of the odontogenic keratocysts and other odontogenic lesions.
de Vicente JC, Torre-Iturraspe A, Gutiérrez AM, Lequerica-Fernández P
Medicina oral, patologia oral y cirugia bucal 2010 Sep 1;15(5):e709-15
Medicina oral, patologia oral y cirugia bucal 2010 Sep 1;15(5):e709-15
D-type cyclins in superficial and muscle-invasive bladder urothelial carcinoma: correlation with clinicopathological data and prognostic significance.
Levidou G, Saetta AA, Karlou M, Thymara I, Pratsinis H, Pavlopoulos P, Isaiadis D, Diamantopoulou K, Patsouris E, Korkolopoulou P
Journal of cancer research and clinical oncology 2010 Oct;136(10):1563-71
Journal of cancer research and clinical oncology 2010 Oct;136(10):1563-71
Immunohistochemical characteristics of diffuse sclerosing variant of papillary carcinoma: comparison with conventional papillary carcinoma.
Koo JS, Shin E, Hong SW
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2010 Oct;118(10):744-52
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2010 Oct;118(10):744-52
Cyclin D1 expression in B-cell lymphomas.
Gladkikh A, Potashnikova D, Korneva E, Khudoleeva O, Vorobjev I
Experimental hematology 2010 Nov;38(11):1047-57
Experimental hematology 2010 Nov;38(11):1047-57
Idiopathic cervical fibrosis--a new member of IgG4-related sclerosing diseases: report of 4 cases, 1 complicated by composite lymphoma.
Cheuk W, Tam FK, Chan AN, Luk IS, Yuen AP, Chan WK, Hung TC, Chan JK
The American journal of surgical pathology 2010 Nov;34(11):1678-85
The American journal of surgical pathology 2010 Nov;34(11):1678-85
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis.
Gonzalez-Suarez E, Jacob AP, Jones J, Miller R, Roudier-Meyer MP, Erwert R, Pinkas J, Branstetter D, Dougall WC
Nature 2010 Nov 4;468(7320):103-7
Nature 2010 Nov 4;468(7320):103-7
Mantle cell lymphoma 12 years after allogeneic bone marrow transplantation occurring simultaneously in recipient and donor.
Christian B, Zhao W, Hamadani M, Sotomayor EM, Navarro W, Devine SM, Racke F, Blum KA
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010 Nov 1;28(31):e629-32
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010 Nov 1;28(31):e629-32
Protein profiling in pathology: analysis and evaluation of 239 frozen tissue biopsies for diagnosis of B-cell lymphomas.
Jansen C, Feuth T, Raemaekers JM, Rijntjes J, Meijer JW, Westenend PJ, van Baarlen J, van Krieken JH, Hebeda KM, Groenen PJ
Proteomics. Clinical applications 2010 May;4(5):519-27
Proteomics. Clinical applications 2010 May;4(5):519-27
Primary plasmacytoma of the cervix in a 21-year-old female patient.
Schor AP, Moraes MP, Bisson FW, Bisson MA, Luiz OM, Bacchi CE
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2010 May;29(3):290-3
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2010 May;29(3):290-3
Characterization of D-cyclin proteins in hematolymphoid neoplasms: lack of specificity of cyclin-D2 and D3 expression in lymphoma subtypes.
Metcalf RA, Zhao S, Anderson MW, Lu ZS, Galperin I, Marinelli RJ, Cherry AM, Lossos IS, Natkunam Y
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010 Mar;23(3):420-33
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010 Mar;23(3):420-33
Most morphologic features in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) do not reliably predict underlying FISH genetics or immunoglobulin heavy chain variable region somatic mutational status.
Garcia CF, Hunt KE, Kang H, Babb A, Gale JM, Vasef MA, Reichard KK
Applied immunohistochemistry & molecular morphology : AIMM 2010 Mar;18(2):119-27
Applied immunohistochemistry & molecular morphology : AIMM 2010 Mar;18(2):119-27
The checkpoint kinase ATM protects against stress-induced elevation of cyclin D1 and potential cell death in neurons.
Hitomi M, Stacey DW
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2010 Jun;77(6):524-33
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2010 Jun;77(6):524-33
p16 and pRb immunohistochemical expression increases with increasing tumour grade in mammary phyllodes tumours.
Karim RZ, Gerega SK, Yang YH, Spillane A, Carmalt H, Scolyer RA, Lee CS
Histopathology 2010 Jun;56(7):868-75
Histopathology 2010 Jun;56(7):868-75
Impact of RING and BRCT domain mutations on BRCA1 protein stability, localization and recruitment to DNA damage.
Nelson AC, Holt JT
Radiation research 2010 Jul;174(1):1-13
Radiation research 2010 Jul;174(1):1-13
Morphological and immunophenotypic features of primary and metastatic giant cell tumour of bone.
Alberghini M, Kliskey K, Krenacs T, Picci P, Kindblom L, Forsyth R, Athanasou NA
Virchows Archiv : an international journal of pathology 2010 Jan;456(1):97-103
Virchows Archiv : an international journal of pathology 2010 Jan;456(1):97-103
Citraconic anhydride: a new antigen retrieval solution.
Leong AS, Haffajee Z
Pathology 2010 Jan;42(1):77-81
Pathology 2010 Jan;42(1):77-81
Papillary microcarcinoma in comparison with larger papillary thyroid carcinoma in BRAF(V600E) mutation, clinicopathological features, and immunohistochemical findings.
Park YJ, Kim YA, Lee YJ, Kim SH, Park SY, Kim KW, Chung JK, Youn YK, Kim KH, Park DJ, Cho BY
Head & neck 2010 Jan;32(1):38-45
Head & neck 2010 Jan;32(1):38-45
Cell cycle regulation in the inner ear sensory epithelia: role of cyclin D1 and cyclin-dependent kinase inhibitors.
Laine H, Sulg M, Kirjavainen A, Pirvola U
Developmental biology 2010 Jan 1;337(1):134-46
Developmental biology 2010 Jan 1;337(1):134-46
Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type.
Huang Y, de Reyniès A, de Leval L, Ghazi B, Martin-Garcia N, Travert M, Bosq J, Brière J, Petit B, Thomas E, Coppo P, Marafioti T, Emile JF, Delfau-Larue MH, Schmitt C, Gaulard P
Blood 2010 Feb 11;115(6):1226-37
Blood 2010 Feb 11;115(6):1226-37
The role of immunohistochemistry in discriminating primary from secondary extramammary Paget disease.
Perrotto J, Abbott JJ, Ceilley RI, Ahmed I
The American Journal of dermatopathology 2010 Apr;32(2):137-43
The American Journal of dermatopathology 2010 Apr;32(2):137-43
CD20-positive multiple myeloma - differential expression of cyclins D1 and D2 suggests a heterogeneous disease.
Quinn J, Percy L, Glassford J, Somana K, Rodriguez-Justo M, Yong K
British journal of haematology 2010 Apr;149(1):156-9
British journal of haematology 2010 Apr;149(1):156-9
Diagnostic and differential diagnostic criteria of lymphoid neoplasms in bone marrow trephine biopsies: a study of 87 cases.
Horváth E, Mezei T, Pávai Z, Turcu M, Demian S, Tóth E, Chira L, Jung I
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2009;50(3):399-406
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2009;50(3):399-406
Targets for molecular therapy in esophageal squamous cell carcinoma: an immunohistochemical analysis.
Boone J, van Hillegersberg R, Offerhaus GJ, van Diest PJ, Borel Rinkes IH, Ten Kate FJ
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 2009;22(6):496-504
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 2009;22(6):496-504
Differences in protein expression and gene amplification of cyclins between colon and rectal adenocarcinomas.
Aamodt R, Jonsdottir K, Andersen SN, Bondi J, Bukholm G, Bukholm IR
Gastroenterology research and practice 2009;2009:285830
Gastroenterology research and practice 2009;2009:285830
Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer.
Jacquemier J, Charafe-Jauffret E, Monville F, Esterni B, Extra JM, Houvenaeghel G, Xerri L, Bertucci F, Birnbaum D
Breast cancer research : BCR 2009;11(2):R23
Breast cancer research : BCR 2009;11(2):R23
A novel small molecule with potent anticancer activity inhibits cell growth by modulating intracellular labile zinc homeostasis.
Huesca M, Lock LS, Khine AA, Viau S, Peralta R, Cukier IH, Jin H, Al-Qawasmeh RA, Lee Y, Wright J, Young A
Molecular cancer therapeutics 2009 Sep;8(9):2586-96
Molecular cancer therapeutics 2009 Sep;8(9):2586-96
CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differentiation from chromophobe renal cell carcinoma.
Sukov WR, Ketterling RP, Lager DJ, Carlson AW, Sinnwell JP, Chow GK, Jenkins RB, Cheville JC
Human pathology 2009 Sep;40(9):1296-303
Human pathology 2009 Sep;40(9):1296-303
Improved diagnostic segregation of mantle cell lymphoma by determination of cyclin D1/D3 expression ratio in formalin-fixed tissue.
Mangseth K, Helgeland L, Klos J, Molven A, Vintermyr OK
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2009 Sep;18(3):150-5
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2009 Sep;18(3):150-5
Clinical and biological significance of CDK4 amplification in well-differentiated and dedifferentiated liposarcomas.
Italiano A, Bianchini L, Gjernes E, Keslair F, Ranchere-Vince D, Dumollard JM, Haudebourg J, Leroux A, Mainguené C, Terrier P, Chibon F, Coindre JM, Pedeutour F
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Sep 15;15(18):5696-703
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Sep 15;15(18):5696-703
Complex analysis of cyclin D1 expression in mantle cell lymphoma: two cyclin D1-negative cases detected.
Stefancikova L, Moulis M, Fabian P, Falkova I, Vasova I, Kren L, Macak J, Smardova J
Journal of clinical pathology 2009 Oct;62(10):948-50
Journal of clinical pathology 2009 Oct;62(10):948-50
Lumican inhibits B16F1 melanoma cell lung metastasis.
Brezillon S, Zeltz C, Schneider L, Terryn C, Vuillermoz B, Ramont L, Perrau C, Pluot M, Diebold MD, Radwanska A, Malicka-Blaszkiewicz M, Maquart FX, Wegrowski Y
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2009 Oct;60 Suppl 4:15-22
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2009 Oct;60 Suppl 4:15-22
Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer.
Volate SR, Muga SJ, Issa AY, Nitcheva D, Smith T, Wargovich MJ
Molecular carcinogenesis 2009 Oct;48(10):920-33
Molecular carcinogenesis 2009 Oct;48(10):920-33
Reduced p16 and increased cyclin D1 and pRb expression are correlated with progression in cutaneous melanocytic tumors.
Karim RZ, Li W, Sanki A, Colman MH, Yang YH, Thompson JF, Scolyer RA
International journal of surgical pathology 2009 Oct;17(5):361-7
International journal of surgical pathology 2009 Oct;17(5):361-7
Differential diagnosis of cyclin D2+ mantle cell lymphoma based on fluorescence in situ hybridization and quantitative real-time-PCR.
Quintanilla-Martinez L, Slotta-Huspenina J, Koch I, Klier M, Hsi ED, de Leval L, Klapper W, Gesk S, Siebert R, Fend F
Haematologica 2009 Nov;94(11):1595-8
Haematologica 2009 Nov;94(11):1595-8
Comparative clinicopathologic and immunohistochemical analysis of uterine sarcomas diagnosed using the World Health Organization classification system.
D'Angelo E, Spagnoli LG, Prat J
Human pathology 2009 Nov;40(11):1571-85
Human pathology 2009 Nov;40(11):1571-85
IgG4-related Sclerosing disease: a potential new etiology of cutaneous pseudolymphoma.
Cheuk W, Lee KC, Chong LY, Yuen ST, Chan JK
The American journal of surgical pathology 2009 Nov;33(11):1713-9
The American journal of surgical pathology 2009 Nov;33(11):1713-9
Diffuse blastoid B-cell lymphoma: a histologically aggressive variant of t(14;18)-negative follicular lymphoma.
Chiu A, Frizzera G, Mathew S, Hyjek EM, Chadburn A, Tam W, Knowles DM, Orazi A
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009 Nov;22(11):1507-17
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009 Nov;22(11):1507-17
Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation.
McCarthy A, Lord CJ, Savage K, Grigoriadis A, Smith DP, Weigelt B, Reis-Filho JS, Ashworth A
The Journal of pathology 2009 Nov;219(3):306-16
The Journal of pathology 2009 Nov;219(3):306-16
Mantle cell lymphoma with flow cytometric evidence of clonal plasmacytic differentiation: a case report.
Naushad H, Choi WW, Page CJ, Sanger WG, Weisenburger DD, Aoun P
Cytometry. Part B, Clinical cytometry 2009 May;76(3):218-24
Cytometry. Part B, Clinical cytometry 2009 May;76(3):218-24
Marginal zone variant of mantle cell lymphoma: CD5-negative cyclin D1-positive variant posing a diagnostic dilemma.
Golardi N, Velasco MR, Elghetany MT
Pathology international 2009 May;59(5):317-21
Pathology international 2009 May;59(5):317-21
Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice.
Svärd J, Rozell B, Toftgård R, Teglund S
Molecular carcinogenesis 2009 May;48(5):408-19
Molecular carcinogenesis 2009 May;48(5):408-19
Epstein-Barr virus-positive B-cell lymphoma of the elderly at a United States tertiary medical center: an uncommon aggressive lymphoma with a nongerminal center B-cell phenotype.
Gibson SE, Hsi ED
Human pathology 2009 May;40(5):653-61
Human pathology 2009 May;40(5):653-61
Determinants of response to epidermal growth factor receptor tyrosine kinase inhibition in squamous cell carcinoma of the head and neck.
Rogers SJ, Box C, Chambers P, Barbachano Y, Nutting CM, Rhŷs-Evans P, Workman P, Harrington KJ, Eccles SA
The Journal of pathology 2009 May;218(1):122-30
The Journal of pathology 2009 May;218(1):122-30
Loss of VHL and hypoxia provokes PAX2 up-regulation in clear cell renal cell carcinoma.
Luu VD, Boysen G, Struckmann K, Casagrande S, von Teichman A, Wild PJ, Sulser T, Schraml P, Moch H
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 May 15;15(10):3297-304
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 May 15;15(10):3297-304
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.
Pysz MA, Leontieva OV, Bateman NW, Uronis JM, Curry KJ, Threadgill DW, Janssen KP, Robine S, Velcich A, Augenlicht LH, Black AR, Black JD
Experimental cell research 2009 May 1;315(8):1415-28
Experimental cell research 2009 May 1;315(8):1415-28
Clinical significance of cyclin D1, fibroblast growth factor receptor 3, and p53 immunohistochemistry in plasma cell myeloma treated with a thalidomide-based regimen.
Kelley TW, Baz R, Hussein M, Karafa M, Cook JR
Human pathology 2009 Mar;40(3):405-12
Human pathology 2009 Mar;40(3):405-12
Immunohistochemical evaluation of 95 bone marrow reactive plasmacytoses.
Ioannou MG, Stathakis E, Lazaris AC, Papathomas T, Tsiambas E, Koukoulis GK
Pathology oncology research : POR 2009 Mar;15(1):25-9
Pathology oncology research : POR 2009 Mar;15(1):25-9
IgG4-related sclerosing mastitis: description of a new member of the IgG4-related sclerosing diseases.
Cheuk W, Chan AC, Lam WL, Chow SM, Crowley P, Lloydd R, Campbell I, Thorburn M, Chan JK
The American journal of surgical pathology 2009 Jul;33(7):1058-64
The American journal of surgical pathology 2009 Jul;33(7):1058-64
Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis.
Da Silva L, Buck L, Simpson PT, Reid L, McCallum N, Madigan BJ, Lakhani SR
Virchows Archiv : an international journal of pathology 2009 Jan;454(1):107-14
Virchows Archiv : an international journal of pathology 2009 Jan;454(1):107-14
Clinical and immunohistochemical features associated with a response to bortezomib in patients with multiple myeloma.
Dawson MA, Opat SS, Taouk Y, Donovan M, Zammit M, Monaghan K, Horvath N, Roberts AW, Prince HM, Hertzberg M, McLean CA, Spencer A
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Jan 15;15(2):714-22
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Jan 15;15(2):714-22
Role of cyclin D1 as a mediator of c-Met- and beta-catenin-induced hepatocarcinogenesis.
Patil MA, Lee SA, Macias E, Lam ET, Xu C, Jones KD, Ho C, Rodriguez-Puebla M, Chen X
Cancer research 2009 Jan 1;69(1):253-61
Cancer research 2009 Jan 1;69(1):253-61
Radiotherapy in laryngeal carcinoma: can a panel of 13 markers predict response?
Wildeman MA, Gibcus JH, Hauptmann M, Begg AC, van Velthuysen ML, Hoebers FJ, Mastik MF, Schuuring E, van der Wal JE, van den Brekel MW
The Laryngoscope 2009 Feb;119(2):316-22
The Laryngoscope 2009 Feb;119(2):316-22
Lithium chloride treatment induces epithelial cell proliferation in xenografted human endometrium.
Polotsky AJ, Zhu L, Santoro N, Pollard JW
Human reproduction (Oxford, England) 2009 Aug;24(8):1960-7
Human reproduction (Oxford, England) 2009 Aug;24(8):1960-7
The in vivo modulatory effects of an anterior-chamber microenvironment on uveal melanoma.
Mudhar HS, Saunders E, Rundle P, Rennie IG, Sisley K
The British journal of ophthalmology 2009 Apr;93(4):535-40
The British journal of ophthalmology 2009 Apr;93(4):535-40
CD43 expression is an adverse prognostic factor in diffuse large B-Cell lymphoma.
Mitrovic Z, Ilic I, Nola M, Aurer I, Sonicki Z, Basic-Kinda S, Radman I, Ajdukovic R, Labar B
Clinical lymphoma & myeloma 2009 Apr;9(2):133-7
Clinical lymphoma & myeloma 2009 Apr;9(2):133-7
Glycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapy.
Mamaghani S, Patel S, Hedley DW
BMC cancer 2009 Apr 30;9:132
BMC cancer 2009 Apr 30;9:132
Jagged 1 is necessary for normal mouse lens formation.
Le TT, Conley KW, Brown NL
Developmental biology 2009 Apr 1;328(1):118-26
Developmental biology 2009 Apr 1;328(1):118-26
Stromal, fibrous, and fatty gastrointestinal tumors in a patient with a PDGFRA gene mutation.
Carney JA, Stratakis CA
The American journal of surgical pathology 2008 Sep;32(9):1412-20
The American journal of surgical pathology 2008 Sep;32(9):1412-20
Morphologic features of 115 lymphomas of the orbit and ocular adnexa categorized according to the World Health Organization classification: are marginal zone lymphomas in the orbit mucosa-associated lymphoid tissue-type lymphomas?
Lagoo AS, Haggerty C, Kim Y, Hammons M, Neufeld K, Redher C, Woodward J, Klintworth GK
Archives of pathology & laboratory medicine 2008 Sep;132(9):1405-16
Archives of pathology & laboratory medicine 2008 Sep;132(9):1405-16
Differences and molecular immunohistochemical parameters in the subtypes of infiltrating ductal breast cancer.
Bertolo C, Guerrero D, Vicente F, Cordoba A, Esteller M, Ropero S, Guillen-Grima F, Martinez-Peñuela JM, Lera JM
American journal of clinical pathology 2008 Sep;130(3):414-24
American journal of clinical pathology 2008 Sep;130(3):414-24
Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients.
Tan DS, Marchió C, Jones RL, Savage K, Smith IE, Dowsett M, Reis-Filho JS
Breast cancer research and treatment 2008 Sep;111(1):27-44
Breast cancer research and treatment 2008 Sep;111(1):27-44
Notch signaling regulates growth and differentiation in the mammalian lens.
Rowan S, Conley KW, Le TT, Donner AL, Maas RL, Brown NL
Developmental biology 2008 Sep 1;321(1):111-22
Developmental biology 2008 Sep 1;321(1):111-22
p16, cyclin D1, Ki-67, and AMACR as markers for dysplasia in Barrett esophagus.
Shi XY, Bhagwandeen B, Leong AS
Applied immunohistochemistry & molecular morphology : AIMM 2008 Oct;16(5):447-52
Applied immunohistochemistry & molecular morphology : AIMM 2008 Oct;16(5):447-52
The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival.
Wang X, Asplund AC, Porwit A, Flygare J, Smith CI, Christensson B, Sander B
British journal of haematology 2008 Oct;143(2):248-52
British journal of haematology 2008 Oct;143(2):248-52
Immunohistochemical and biogenetic features of diffuse-type tenosynovial giant cell tumors: the potential roles of cyclin A, P53, and deletion of 15q in sarcomatous transformation.
Huang HY, West RB, Tzeng CC, van de Rijn M, Wang JW, Chou SC, Huang WW, Eng HL, Lin CN, Yu SC, Wu JM, Lu CC, Li CF
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Oct 1;14(19):6023-32
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Oct 1;14(19):6023-32
Exploration of the APC/beta-catenin (WNT) pathway and a histologic classification system for pulmonary artery intimal sarcoma. A study of 18 cases.
Gaumann A, Bode-Lesniewska B, Zimmermann DR, Fanburg-Smith JC, Kirkpatrick CJ, Hofstädter F, Woenckhaus M, Stoehr R, Obermann EC, Dietmaier W, Hartmann A
Virchows Archiv : an international journal of pathology 2008 Nov;453(5):473-84
Virchows Archiv : an international journal of pathology 2008 Nov;453(5):473-84
Activated Akt as an indicator of prognosis in gastric cancer.
Cinti C, Vindigni C, Zamparelli A, La Sala D, Epistolato MC, Marrelli D, Cevenini G, Tosi P
Virchows Archiv : an international journal of pathology 2008 Nov;453(5):449-55
Virchows Archiv : an international journal of pathology 2008 Nov;453(5):449-55
Immunohistochemical evaluation of a panel of tumor cell markers during malignant progression in Barrett esophagus.
van Dekken H, Hop WC, Tilanus HW, Haringsma J, van der Valk H, Wink JC, Vissers KJ
American journal of clinical pathology 2008 Nov;130(5):745-53
American journal of clinical pathology 2008 Nov;130(5):745-53
Heterozygous mutations in the tumor suppressor gene PATCHED provoke basal cell carcinoma-like features in human organotypic skin cultures.
Brellier F, Bergoglio V, Valin A, Barnay S, Chevallier-Lagente O, Vielh P, Spatz A, Gorry P, Avril MF, Magnaldo T
Oncogene 2008 Nov 20;27(51):6601-6
Oncogene 2008 Nov 20;27(51):6601-6
Oligomeric proanthocyanidin complexes (OPC) exert anti-proliferative and pro-apoptotic effects on prostate cancer cells.
Neuwirt H, Arias MC, Puhr M, Hobisch A, Culig Z
The Prostate 2008 Nov 1;68(15):1647-54
The Prostate 2008 Nov 1;68(15):1647-54
Proliferating active cells, lymphocyte subsets, and dendritic cells in recurrent tonsillitis: their effect on hypertrophy.
Alatas N, Baba F
Archives of otolaryngology--head & neck surgery 2008 May;134(5):477-83
Archives of otolaryngology--head & neck surgery 2008 May;134(5):477-83
Cyclin D1 overexpression, p16 loss, and pRb inactivation play a key role in pulmonary carcinogenesis and have a prognostic implication for the long-term survival in non-small cell lung carcinoma patients.
Myong NH
Cancer research and treatment 2008 Jun;40(2):45-52
Cancer research and treatment 2008 Jun;40(2):45-52
S100A4 expression is associated with lymph node metastasis in papillary microcarcinoma of the thyroid.
Min HS, Choe G, Kim SW, Park YJ, Park DJ, Youn YK, Park SH, Cho BY, Park SY
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008 Jun;21(6):748-55
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008 Jun;21(6):748-55
Regulation of keratinocyte proliferation in rats with deep, partial-thickness scald: modulation of cyclin D1-cyclin-dependent kinase 4 and histone H1 kinase activity of M-phase promoting factor.
Xie T, Niu Y, Ge K, Lu S
The Journal of surgical research 2008 Jun 1;147(1):9-14
The Journal of surgical research 2008 Jun 1;147(1):9-14
Mantle cell lymphoma lacking the t(11;14) translocation: a case report and brief review of the literature.
Hunt KE, Reichard KK, Wilson CS
Journal of clinical pathology 2008 Jul;61(7):869-70
Journal of clinical pathology 2008 Jul;61(7):869-70
Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs).
Haller F, Löbke C, Ruschhaupt M, Cameron S, Schulten HJ, Schwager S, von Heydebreck A, Gunawan B, Langer C, Ramadori G, Sültmann H, Poustka A, Korf U, Füzesi L
The Journal of pathology 2008 Jul;215(3):253-62
The Journal of pathology 2008 Jul;215(3):253-62
MYC translocation in chronic lymphocytic leukaemia is associated with increased prolymphocytes and a poor prognosis.
Huh YO, Lin KI, Vega F, Schlette E, Yin CC, Keating MJ, Luthra R, Medeiros LJ, Abruzzo LV
British journal of haematology 2008 Jul;142(1):36-44
British journal of haematology 2008 Jul;142(1):36-44
Molecular characterization of synovial sarcoma in children and adolescents: evidence of akt activation.
Bozzi F, Ferrari A, Negri T, Conca E, Luca da R, Losa M, Casieri P, Orsenigo M, Lampis A, Meazza C, Casanova M, Pierotti MA, Tamborini E, Pilotti S
Translational oncology 2008 Jul;1(2):95-101
Translational oncology 2008 Jul;1(2):95-101
Impaired E-cadherin expression and glutamine synthetase overexpression in solid pseudopapillary neoplasm of the pancreas.
Audard V, Cavard C, Richa H, Infante M, Couvelard A, Sauvanet A, Terris B, Paye F, Flejou JF
Pancreas 2008 Jan;36(1):80-3
Pancreas 2008 Jan;36(1):80-3
Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells.
Vogetseder A, Picard N, Gaspert A, Walch M, Kaissling B, Le Hir M
American journal of physiology. Cell physiology 2008 Jan;294(1):C22-8
American journal of physiology. Cell physiology 2008 Jan;294(1):C22-8
Gene expression profile analysis of epilepsy-associated gangliogliomas.
Aronica E, Boer K, Becker A, Redeker S, Spliet WG, van Rijen PC, Wittink F, Breit T, Wadman WJ, Lopes da Silva FH, Troost D, Gorter JA
Neuroscience 2008 Jan 2;151(1):272-92
Neuroscience 2008 Jan 2;151(1):272-92
Effects of estradiol and medroxyprogesterone acetate on expression of the cell cycle proteins cyclin D1, p21 and p27 in cultured human breast tissues.
Eigeliene N, Härkönen P, Erkkola R
Cell cycle (Georgetown, Tex.) 2008 Jan 1;7(1):71-80
Cell cycle (Georgetown, Tex.) 2008 Jan 1;7(1):71-80
Effects of estradiol and medroxyprogesterone acetate on expression of the cell cycle proteins cyclin D1, p21 and p27 in cultured human breast tissues.
Eigeliene N, Härkönen P, Erkkola R
Cell cycle (Georgetown, Tex.) 2008 Jan 1;7(1):71-80
Cell cycle (Georgetown, Tex.) 2008 Jan 1;7(1):71-80
Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche.
Kubota Y, Takubo K, Suda T
Biochemical and biophysical research communications 2008 Feb 8;366(2):335-9
Biochemical and biophysical research communications 2008 Feb 8;366(2):335-9
Human thyroid tumours, the puzzling lessons from E7 and RET/PTC3 transgenic mice.
Jin L, Burniat A, Dumont JE, Miot F, Corvilain B, Franc B
British journal of cancer 2008 Dec 2;99(11):1874-83
British journal of cancer 2008 Dec 2;99(11):1874-83
Chromosome 11 genomic changes in parathyroid adenoma and hyperplasia: array CGH, FISH, and tissue microarrays.
Yi Y, Nowak NJ, Pacchia AL, Morrison C
Genes, chromosomes & cancer 2008 Aug;47(8):639-48
Genes, chromosomes & cancer 2008 Aug;47(8):639-48
Ocular adnexal lymphoma associated with IgG4+ chronic sclerosing dacryoadenitis: a previously undescribed complication of IgG4-related sclerosing disease.
Cheuk W, Yuen HK, Chan AC, Shih LY, Kuo TT, Ma MW, Lo YF, Chan WK, Chan JK
The American journal of surgical pathology 2008 Aug;32(8):1159-67
The American journal of surgical pathology 2008 Aug;32(8):1159-67
Cyclin D1 in excitatory neurons of the adult brain enhances kainate-induced neurotoxicity.
Koeller HB, Ross ME, Glickstein SB
Neurobiology of disease 2008 Aug;31(2):230-41
Neurobiology of disease 2008 Aug;31(2):230-41
Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast.
Marchiò C, Iravani M, Natrajan R, Lambros MB, Savage K, Tamber N, Fenwick K, Mackay A, Senetta R, Di Palma S, Schmitt FC, Bussolati G, Ellis LO, Ashworth A, Sapino A, Reis-Filho JS
The Journal of pathology 2008 Aug;215(4):398-410
The Journal of pathology 2008 Aug;215(4):398-410
Primary extramedullary plasmacytoma: similarities with and differences from multiple myeloma revealed by interphase cytogenetics.
Bink K, Haralambieva E, Kremer M, Ott G, Beham-Schmid C, de Leval L, Peh SC, Laeng HR, Jütting U, Hutzler P, Quintanilla-Martinez L, Fend F
Haematologica 2008 Apr;93(4):623-6
Haematologica 2008 Apr;93(4):623-6
Immunoexpression and prognostic role of hTERT and cyclin D1 in urothelial carcinoma.
Yang CH, Hung WC, Wang SL, Kang WY, Chen WT, Huang YC, Su YC, Chai CY
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2008 Apr;116(4):309-16
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2008 Apr;116(4):309-16
Wnt pathway-related gene expression during malignant progression in ulcerative colitis.
van Dekken H, Wink JC, Vissers KJ, Franken PF, Ruud Schouten W, J Hop WC, Kuipers EJ, Fodde R, Janneke van der Woude C
Acta histochemica 2007;109(4):266-72
Acta histochemica 2007;109(4):266-72
The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma.
van der Vegt B, de Roos MA, Peterse JL, Patriarca C, Hilkens J, de Bock GH, Wesseling J
Histopathology 2007 Sep;51(3):322-35
Histopathology 2007 Sep;51(3):322-35
The reliability of lymphoma diagnosis in small tissue samples is heavily influenced by lymphoma subtype.
Farmer PL, Bailey DJ, Burns BF, Day A, LeBrun DP
American journal of clinical pathology 2007 Sep;128(3):474-80
American journal of clinical pathology 2007 Sep;128(3):474-80
Co-expression of cyclin D1 and phosphorylated ribosomal S6 proteins in hemimegalencephaly.
Aronica E, Boer K, Baybis M, Yu J, Crino P
Acta neuropathologica 2007 Sep;114(3):287-93
Acta neuropathologica 2007 Sep;114(3):287-93
Clinical outcome of incidental pelvic node malignant B-cell lymphomas discovered at the time of radical prostatectomy.
He H, Cheng L, Weiss LM, Chu PG
Leukemia & lymphoma 2007 Oct;48(10):1976-80
Leukemia & lymphoma 2007 Oct;48(10):1976-80
The effect of the sun on expression of beta-catenin, p16 and cyclin d1 proteins in melanocytic lesions.
Demirkan NC, Kesen Z, Akdag B, Larue L, Delmas V
Clinical and experimental dermatology 2007 Nov;32(6):733-9
Clinical and experimental dermatology 2007 Nov;32(6):733-9
Selective cortical interneuron and GABA deficits in cyclin D2-null mice.
Glickstein SB, Moore H, Slowinska B, Racchumi J, Suh M, Chuhma N, Ross ME
Development (Cambridge, England) 2007 Nov;134(22):4083-93
Development (Cambridge, England) 2007 Nov;134(22):4083-93
Immunohistochemical analysis with multiple antibodies in search of prognostic markers for clear cell renal cell carcinoma.
Phuoc NB, Ehara H, Gotoh T, Nakano M, Yokoi S, Deguchi T, Hirose Y
Urology 2007 May;69(5):843-8
Urology 2007 May;69(5):843-8
Cyclin D1 and t(11;14)-positive B-cell neoplasms resembling marginal zone B-cell lymphoma: a morphological variant of mantle cell lymphoma.
Mansoor A, Akbari M, Auer I, Lai R
Human pathology 2007 May;38(5):797-802
Human pathology 2007 May;38(5):797-802
Should parafibromin staining replace HRTP2 gene analysis as an additional tool for histologic diagnosis of parathyroid carcinoma?
Cetani F, Ambrogini E, Viacava P, Pardi E, Fanelli G, Naccarato AG, Borsari S, Lemmi M, Berti P, Miccoli P, Pinchera A, Marcocci C
European journal of endocrinology 2007 May;156(5):547-54
European journal of endocrinology 2007 May;156(5):547-54
Leptin-mediated decrease of cyclin A2 and increase of cyclin D1 expression: relevance for the control of prepubertal rat Leydig cell division and differentiation.
Fombonne J, Charrier C, Goddard I, Moyse E, Krantic S
Endocrinology 2007 May;148(5):2126-37
Endocrinology 2007 May;148(5):2126-37
Involvement of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice.
Okano J, Suzuki S, Shiota K
Toxicology and applied pharmacology 2007 May 15;221(1):42-56
Toxicology and applied pharmacology 2007 May 15;221(1):42-56
Immunophenotypic profiling of nonsmall cell lung cancer progression using the tissue microarray approach.
Papay J, Krenacs T, Moldvay J, Stelkovics E, Furak J, Molnar B, Kopper L
Applied immunohistochemistry & molecular morphology : AIMM 2007 Mar;15(1):19-30
Applied immunohistochemistry & molecular morphology : AIMM 2007 Mar;15(1):19-30
Immunohistochemical expression of beta-catenin, E-cadherin, cyclin D1 and c-myc in benign trichogenic tumors.
Demirkan NC, Bir F, Erdem O, Düzcan E
Journal of cutaneous pathology 2007 Jun;34(6):467-73
Journal of cutaneous pathology 2007 Jun;34(6):467-73
Pathological and biological differences between screen-detected and interval ductal carcinoma in situ of the breast.
de Roos MA, van der Vegt B, de Vries J, Wesseling J, de Bock GH
Annals of surgical oncology 2007 Jul;14(7):2097-104
Annals of surgical oncology 2007 Jul;14(7):2097-104
The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry.
Wong SC, Chan JK, Lo ES, Chan AK, Wong MC, Chan CM, Lam MY, Chan AT
Archives of pathology & laboratory medicine 2007 Jul;131(7):1047-55
Archives of pathology & laboratory medicine 2007 Jul;131(7):1047-55
Expression of cyclin D1 and Ki-67 in squamous cell carcinoma of the penis.
Papadopoulos O, Betsi E, Tsakistou G, Frangoulis M, Kouvatseas G, Anagnostakis D, Kouvidou Ch
Anticancer research 2007 Jul-Aug;27(4B):2167-74
Anticancer research 2007 Jul-Aug;27(4B):2167-74
Cell cycle regulators and outcome of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer: the International Adjuvant Lung Cancer Trial Biologic Program.
Filipits M, Pirker R, Dunant A, Lantuejoul S, Schmid K, Huynh A, Haddad V, André F, Stahel R, Pignon JP, Soria JC, Popper HH, Le Chevalier T, Brambilla E
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007 Jul 1;25(19):2735-40
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007 Jul 1;25(19):2735-40
Developmental expression of cell cycle regulators in the baboon fetal adrenal gland.
Dumitrescu A, Aberdeen GW, Pepe GJ, Albrecht ED
The Journal of endocrinology 2007 Jan;192(1):237-47
The Journal of endocrinology 2007 Jan;192(1):237-47
The t(14;19)(q32;q13)-positive small B-cell leukaemia: a clinicopathologic and cytogenetic study of seven cases.
Huh YO, Abruzzo LV, Rassidakis GZ, Parry-Jones N, Schlette E, Brito-Bapabulle V, Matutes E, Wotherspoon A, Keating MJ, Medeiros LJ, Catovsky D
British journal of haematology 2007 Jan;136(2):220-8
British journal of haematology 2007 Jan;136(2):220-8
Expression of human telomerase reverse transcriptase and cyclin-D1 in olfactory neuroblastoma.
Wang SL, Chen WT, Li SH, Li SW, Yang SF, Chai CY
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2007 Jan;115(1):17-21
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2007 Jan;115(1):17-21
Proximal tubular epithelial cells are generated by division of differentiated cells in the healthy kidney.
Vogetseder A, Palan T, Bacic D, Kaissling B, Le Hir M
American journal of physiology. Cell physiology 2007 Feb;292(2):C807-13
American journal of physiology. Cell physiology 2007 Feb;292(2):C807-13
Frequency and distribution of trisomy 11 in multiple myeloma patients: relation with overexpression of CCND1 and t(11;14).
Guglielmelli T, Giugliano E, Cappia S, Papotti M, Saglio G
Cancer genetics and cytogenetics 2007 Feb;173(1):51-6
Cancer genetics and cytogenetics 2007 Feb;173(1):51-6
Cell cycle regulators show diagnostic and prognostic utility for differentiated thyroid cancer.
Melck A, Masoudi H, Griffith OL, Rajput A, Wilkins G, Bugis S, Jones SJ, Wiseman SM
Annals of surgical oncology 2007 Dec;14(12):3403-11
Annals of surgical oncology 2007 Dec;14(12):3403-11
The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome in 'pure' ductal carcinoma in situ of the breast.
de Roos MA, van der Vegt B, Peterse JL, Patriarca C, de Vries J, de Bock GH, Wesseling J
Histopathology 2007 Aug;51(2):227-38
Histopathology 2007 Aug;51(2):227-38
Diagnostic value of galectin-3, HBME-1, cytokeratin 19, high molecular weight cytokeratin, cyclin D1 and p27(kip1) in the differential diagnosis of thyroid nodules.
Park YJ, Kwak SH, Kim DC, Kim H, Choe G, Park DJ, Jang HC, Park SH, Cho BY, Park SY
Journal of Korean medical science 2007 Aug;22(4):621-8
Journal of Korean medical science 2007 Aug;22(4):621-8
Synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: case report.
El Demellawy D, Ross C, Sur M, Alowami S
Diagnostic pathology 2007 Aug 30;2:34
Diagnostic pathology 2007 Aug 30;2:34
New evidence for geographic variation in the role of human papillomavirus in tonsillar carcinogenesis.
Li W, Tran N, Lee SC, O'Brien CJ, Tse GM, Scolyer RA, Hong A, Milross C, Yu KH, Rose BR
Pathology 2007 Apr;39(2):217-22
Pathology 2007 Apr;39(2):217-22
Overlapping morphologic and immunophenotypic profiles in small B-cell lymphoma. A report of two cases.
Kostopoulos I, Cocco M, Ginanneschi C, D'Amuri A, Lazzi S, Fabbri A, Forconi F, De Santi MM, Leoncini L
Virchows Archiv : an international journal of pathology 2006 Sep;449(3):320-7
Virchows Archiv : an international journal of pathology 2006 Sep;449(3):320-7
Tissue microarray profiling of primary and xenotransplanted synovial sarcomas demonstrates the immunophenotypic similarities existing between SYT-SSX fusion gene confirmed, biphasic, and monophasic fibrous variants.
Subramaniam MM, Navarro S, Pellin A, López-Guerrero JA, Carda C, Heredia Alvaro JA, Gozalbo Sabater PL, Llombart-Bosch A
Virchows Archiv : an international journal of pathology 2006 Oct;449(4):435-47
Virchows Archiv : an international journal of pathology 2006 Oct;449(4):435-47
Lymphomas involving the pleura: a clinicopathologic study of 34 cases diagnosed by pleural biopsy.
Vega F, Padula A, Valbuena JR, Stancu M, Jones D, Medeiros LJ
Archives of pathology & laboratory medicine 2006 Oct;130(10):1497-502
Archives of pathology & laboratory medicine 2006 Oct;130(10):1497-502
P27, SKP2, and extra-cellular signal-related kinase signalling in human salivary gland mucoepidermoid carcinoma.
Handra-Luca A, Ruhin B, Lesty C, Fouret P
Oral oncology 2006 Nov;42(10):1005-10
Oral oncology 2006 Nov;42(10):1005-10
Identification of target genes in laryngeal squamous cell carcinoma by high-resolution copy number and gene expression microarray analyses.
Järvinen AK, Autio R, Haapa-Paananen S, Wolf M, Saarela M, Grénman R, Leivo I, Kallioniemi O, Mäkitie AA, Monni O
Oncogene 2006 Nov 2;25(52):6997-7008
Oncogene 2006 Nov 2;25(52):6997-7008
FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas.
Reis-Filho JS, Simpson PT, Turner NC, Lambros MB, Jones C, Mackay A, Grigoriadis A, Sarrio D, Savage K, Dexter T, Iravani M, Fenwick K, Weber B, Hardisson D, Schmitt FC, Palacios J, Lakhani SR, Ashworth A
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Nov 15;12(22):6652-62
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Nov 15;12(22):6652-62
Molecular and cytogenetic subgroups of oropharyngeal squamous cell carcinoma.
Perrone F, Suardi S, Pastore E, Casieri P, Orsenigo M, Caramuta S, Dagrada G, Losa M, Licitra L, Bossi P, Staurengo S, Oggionni M, Locati L, Cantu G, Squadrelli M, Carbone A, Pierotti MA, Pilotti S
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Nov 15;12(22):6643-51
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Nov 15;12(22):6643-51
Molecular characterization of composite mantle cell and follicular lymphoma.
Zamò A, Zanotti R, Lestani M, Ott G, Katzenberger T, Scarpa A, Pizzolo G, Menestrina F, Chilosi M
Virchows Archiv : an international journal of pathology 2006 May;448(5):639-43
Virchows Archiv : an international journal of pathology 2006 May;448(5):639-43
Overexpression of cyclins D1 and D3 during estrogen-induced breast oncogenesis in female ACI rats.
Weroha SJ, Li SA, Tawfik O, Li JJ
Carcinogenesis 2006 Mar;27(3):491-8
Carcinogenesis 2006 Mar;27(3):491-8
Loss of parafibromin expression in a subset of parathyroid adenomas.
Juhlin C, Larsson C, Yakoleva T, Leibiger I, Leibiger B, Alimov A, Weber G, Höög A, Villablanca A
Endocrine-related cancer 2006 Jun;13(2):509-23
Endocrine-related cancer 2006 Jun;13(2):509-23
Mantle cell lymphoma in Taiwan: clinicopathological and molecular study of 21 cases including one cyclin D1-negative tumor expressing cyclin D2.
Chuang SS, Huang WT, Hsieh PP, Tseng HH, Campo E, Colomer D, Ye H, Lu CL, Chang HM, Cho CY, Huang SH, Lu YC, Wu JD
Pathology international 2006 Aug;56(8):440-8
Pathology international 2006 Aug;56(8):440-8
Ocular adnexal marginal zone B cell lymphoma: a clinical and pathologic study of 23 cases.
Charlotte F, Doghmi K, Cassoux N, Ye H, Du MQ, Kujas M, Lesot A, Mansour G, Lehoang P, Vignot N, Capron F, Leblond V
Virchows Archiv : an international journal of pathology 2006 Apr;448(4):506-16
Virchows Archiv : an international journal of pathology 2006 Apr;448(4):506-16
Z-138 cell line was derived from a patient with blastoid variant mantle cell lymphoma.
Medeiros LJ, Estrov Z, Rassidakis GZ
Leukemia research 2006 Apr;30(4):497-501
Leukemia research 2006 Apr;30(4):497-501
Immunohistochemical analysis identifies two cyclin D1+ subsets of plasma cell myeloma, each associated with favorable survival.
Cook JR, Hsi ED, Worley S, Tubbs RR, Hussein M
American journal of clinical pathology 2006 Apr;125(4):615-24
American journal of clinical pathology 2006 Apr;125(4):615-24
Immunophenotypic profile of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia.
Konoplev S, Medeiros LJ, Bueso-Ramos CE, Jorgensen JL, Lin P
American journal of clinical pathology 2005 Sep;124(3):414-20
American journal of clinical pathology 2005 Sep;124(3):414-20
Transforming growth factor beta 1 promotes cell cycle exit through the cyclin-dependent kinase inhibitor p21 in the developing cerebral cortex.
Siegenthaler JA, Miller MW
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 Sep 21;25(38):8627-36
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 Sep 21;25(38):8627-36
The kd/kd mouse is a model of collapsing glomerulopathy.
Barisoni L, Madaio MP, Eraso M, Gasser DL, Nelson PJ
Journal of the American Society of Nephrology : JASN 2005 Oct;16(10):2847-51
Journal of the American Society of Nephrology : JASN 2005 Oct;16(10):2847-51
Ethanol disrupts cell cycle regulation in developing rat cortex interaction with transforming growth factor beta1.
Siegenthaler JA, Miller MW
Journal of neurochemistry 2005 Nov;95(3):902-12
Journal of neurochemistry 2005 Nov;95(3):902-12
Increase in Ara-C cytotoxicity in the presence of valproate, a histone deacetylase inhibitor, is associated with the concurrent expression of cyclin D1 and p27(Kip 1) in acute myeloblastic leukemia cells.
Siitonen T, Koistinen P, Savolainen ER
Leukemia research 2005 Nov;29(11):1335-42
Leukemia research 2005 Nov;29(11):1335-42
Antibody selection in immunohistochemical detection of cyclin D1 in mantle cell lymphoma.
Torlakovic E, Nielsen S, Vyberg M
American journal of clinical pathology 2005 Nov;124(5):782-9
American journal of clinical pathology 2005 Nov;124(5):782-9
The cell cycle-apoptosis connection revisited in the adult brain.
Bauer S, Patterson PH
The Journal of cell biology 2005 Nov 21;171(4):641-50
The Journal of cell biology 2005 Nov 21;171(4):641-50
Mantle cell lymphomas with low levels of cyclin D1 long mRNA transcripts are highly proliferative and can be discriminated by elevated cyclin A2 and cyclin B1.
Sander B, Flygare J, Porwit-Macdonald A, Smith CI, Emanuelsson E, Kimby E, Liden J, Christensson B
International journal of cancer 2005 Nov 10;117(3):418-30
International journal of cancer 2005 Nov 10;117(3):418-30
Low level of cyclin D1 protein expression in thyroid microcarcinomas from an autopsy series.
Kovacs GL, Stelkovics E, Krenacs L, Gonda G, Goth M, Kovacs L, Gorombey Z, Hubina E, Szabolcs I
Endocrine 2005 Feb;26(1):41-4
Endocrine 2005 Feb;26(1):41-4
HDPR1, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencing.
Yau TO, Chan CY, Chan KL, Lee MF, Wong CM, Fan ST, Ng IO
Oncogene 2005 Feb 24;24(9):1607-14
Oncogene 2005 Feb 24;24(9):1607-14
Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling.
Fu K, Weisenburger DD, Greiner TC, Dave S, Wright G, Rosenwald A, Chiorazzi M, Iqbal J, Gesk S, Siebert R, De Jong D, Jaffe ES, Wilson WH, Delabie J, Ott G, Dave BJ, Sanger WG, Smith LM, Rimsza L, Braziel RM, Müller-Hermelink HK, Campo E, Gascoyne RD, Staudt LM, Chan WC, Lymphoma/Leukemia Molecular Profiling Project
Blood 2005 Dec 15;106(13):4315-21
Blood 2005 Dec 15;106(13):4315-21
Clinicopathologic and genetic profile of intracranial marginal zone lymphoma: a primary low-grade CNS lymphoma that mimics meningioma.
Tu PH, Giannini C, Judkins AR, Schwalb JM, Burack R, O'Neill BP, Yachnis AT, Burger PC, Scheithauer BW, Perry A
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 Aug 20;23(24):5718-27
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 Aug 20;23(24):5718-27
Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase-immortalized human mesenchymal stem cells.
Burns JS, Abdallah BM, Guldberg P, Rygaard J, Schrøder HD, Kassem M
Cancer research 2005 Apr 15;65(8):3126-35
Cancer research 2005 Apr 15;65(8):3126-35
Consistent immunostaining for cyclin D1 can be achieved on a routine basis using a newly available rabbit monoclonal antibody.
Cheuk W, Wong KO, Wong CS, Chan JK
The American journal of surgical pathology 2004 Jun;28(6):801-7
The American journal of surgical pathology 2004 Jun;28(6):801-7
Consistent immunostaining for cyclin D1 can be achieved on a routine basis using a newly available rabbit monoclonal antibody.
Cheuk W, Wong KO, Wong CS, Chan JK
The American journal of surgical pathology 2004 Jun;28(6):801-7
The American journal of surgical pathology 2004 Jun;28(6):801-7
The small leucine-rich proteoglycan lumican inhibits melanoma progression.
Vuillermoz B, Khoruzhenko A, D'Onofrio MF, Ramont L, Venteo L, Perreau C, Antonicelli F, Maquart FX, Wegrowski Y
Experimental cell research 2004 Jun 10;296(2):294-306
Experimental cell research 2004 Jun 10;296(2):294-306
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- Western blot analysis of MCF7 Cells using anti-Cyclin D1 Monoclonal Antibody (Product # MA5-16356). The recommened dilution for this antibody in western blot applications is 1:25.
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- Knockdown of Cyclin D1 was achieved by transfecting HeLa cells with Cyclin D1 specific validated siRNAs (Silencer® select Product # s230). Western blot analysis (Fig. a) was performed using modified whole cell extracts (1% SDS) from the Cyclin D1 knockdown cells (lane 3), non-specific scrambled siRNA transfected cells (lane 2) and untransfected cells (lane 1). The blots were probed with Cyclin D1 Monoclonal Antibody (Product # MA5-16356, 1:500 dilution) and Goat anti-Rabbit IgG (H+L) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). Densitometric analysis of this western blot is shown in histogram (Fig b). Decrease in signal upon siRNA mediated knock down confirms that antibody is specific to 4EBP1.
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- Western blot analysis was performed on modified whole cell extracts (1% SDS) of HeLa (Lane 1), U-87 MG (Lane 2), COLO 205 (Lane 3), A-431 (Lane 4) and NIH/3T3 (Lane 5). The blot was probed with Anti-Cyclin D1 antibody (Product # MA5-16356, 1:500 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (H+L) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). A 36 kDa band corresponding to 14-3-3 sigma was observed across the cell lines tested.
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- Immunofluorescence analysis of Cyclin D1 was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Cyclin D1 Rabbit Monoclonal Antibody (Product # MA1-39546) at 1:250 dilution in 0.1% BSA and incubated overnight at 4 degree and then labeled with Goat anti-Rabbit IgG (H+L) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) at a dilution of 1:2000 for 45 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). F-actin (Panel c: red) was stained with Rhodamine Phalloidin (Product # R415, 1:300). Panel d represents the merged image showing nuclear localization. Panel e represents control cells with no primary antibody to assess background. The images were captured at 60X magnification.
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- Immunohistochemical analysis of Cyclin D1 using anti-Cyclin D1 Monoclonal Antibody (Product # MA5-16356) in Mantle Cell Lymphoma Cancer Tissue. The recommened dilution for this antibody in immunohistochemistry applications is 1:100.
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- Fig 3 Conditional Pax6 expression in Tis21-positive APs increases S-phase in the AP and BP progeny. Dorsolateral telencephalon of tamoxifen-treated E14.5 Tis21 -CreER T2 heterozygous mice electroporated at E13.5 with control ( A , C , D , F , G , I , J , L ) or Pax6-expressing ( B , C , E , F , H , I , K , L ) plasmid (see Fig 2B ). ( A - C ) EdU was administered one hour before sacrifice. ( A , B ) EdU (white) and RFP (red) fluorescence, combined with DAPI staining (blue), on coronal 50-mum vibratome sections. Insets show representative examples of RFP-positive nuclei (outlined by dashed yellow lines) that are either EdU-positive (yellow arrows, see also main panels) or-negative (yellow arrowheads). ( C ) Quantification of EdU- and RFP-positive cells in the cortical wall (total), VZ and SVZ, expressed as percentage of all RFP-positive cells in the cortical wall (200-mum wide area), upon control (Con, white) and Pax6 (black) electroporation. ( D , E ) Proliferating cell nuclear antigen (PCNA) immunofluorescence (white) and RFP fluorescence (red), combined with DAPI staining (blue), on coronal 12-mum cryosections. Insets show representative examples of RFP-positive nuclei (outlined by dashed yellow lines) that show either a punctate immunoreactivity (yellow arrows, see also main panels), indicative of S-phase, or a diffuse immunoreactivity (yellow arrowheads), indicative of G1 or G2. ( F ) Quantification of punctate PCNA-positive nuclei and RFP-positive cells in the cortical w
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- Figure 2 Liver regeneration after partial hepatectomy (PHx) in MICU1 KD and Ctrl liver. ( a ) Representative images of haematoxylin and eosin (H&E)-stained liver tissue and quantification of necrotic area in Ctrl and KD mice before (LL, left lateral lobe) and 30 h after PHx (Phx 30 h; collected from the same mouse for individual comparison). Magnified image displays a typical necrotic area in KD liver 30 h after PHx along with quantification. Scale bars, 200 mum (mean+-s.e.m., n =4 per group). ( b ) Serum levels of alanine aminotransferase (ALT), direct and total bilirubin and triglycerides in Ctrl and KD mice 30 h post PHx, or after sham surgery (mean+-s.e.m., n =3-6 per group). ( c ) BrdU immunostaining and quantification 30 h post PHx in Ctrl and KD mouse liver. Scale bars, 50 mum (mean+-s.e.m., n =4 per group). ( d ) Immunoblotting of Cyclin D1 expression and quantification in Ctrl and KD liver lysates before PHx (LL) and 30 h post Sham operated or PHx (mean+-s.e.m., n =4 per group). Values are mean+-s.e.m., ** P
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- Figure 4 Prevention of mitochondrial Ca 2+ overload rescues liver regeneration in MICU1 KD mice. ( a ) Assessment of Ca 2+ overload-induced mitochondrial PTP opening in Ctrl and KD permeabilized hepatocytes. Extramitochondrial [Ca 2+ ] was recorded during repetitive addition of CaCl 2 boluses (1 muM each) in the absence (Mock) or presence of RuRed (3 muM) or NIM811 (2 muM). Right panel: Ca 2+ load dependence of PTP opening shown as Ca 2+ efflux via PTP (Mock minus NIM811) plotted against the mitochondrial Ca 2+ uptake (RuRed minus Mock), mean traces of triplicates. Representative of n =4 independent experiments. ( b ) Representative images of haematoxylin and eosin (H&E)-stained liver tissue 30 h post PHx showing the absence of necrotic area in both Ctrl and KD liver treated without and with 10 mg kg -1 NIM811 (4 separate mice). Liver necrosis was evident in vehicle (Veh)-treated KD mice. Scale bars, 200 mum. ( c ) BrdU immunostaining and quantification 30 h post PHx in Ctrl and KD mouse liver. Scale bars, 50 mum (mean+-s.e.m., n =5 per group). ( d ) Serum levels of ALT, direct and total bilirubin and triglycerides in Ctrl and KD mice after 30 h of PHx and treated with either vehicle or NIM811. (mean+-s.e.m., n =5 per group). ( e ) Cyclin D1 expression assessed by immunoblotting in Ctrl and KD liver lysates of Ctrl and KD mice treated with NIM811 or vehicle before (LL) and after 30 h PHx (mean+-s.e.m., n =3-4/group). Values are mean+-s.e.m., * P
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- Figure 5 The expression of D-cyclins in mantle cell lymphoma The differential expression of D-cyclin staining in two case examples of mantle cell lymphoma is shown. Case 1 shows intense cyclin D1 and weak cyclin D2 staining. Case 2 shows weak cyclin D1 and strong cyclin D2 staining. Both cases lack staining for cyclin D3.
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- 2 FIGURE Circ-UBAP2 silencing repressed cell proliferation, migration, and invasion, and enhanced apoptosis in vitro. A172 and U251 cells were transfected with si-NC or si-circ-UBAP2. (A) Circ-UBAP2 level was assessed by qRT-PCR. (B) Cell viability was gauged using a CCK-8 assay. (C) Colony formation was evaluated using colony formation assay. (D) Cell apoptosis was detected using flow cytometry. (E, F) Cell migration and invasion were gauged using transwell assay. (G) Cell migration was monitored using wound-healing assay. (H, I) The levels of CyclinD1 and MMP9 by western blot. ** p < 0.01, *** p < 0.001, or **** p < 0.0001
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- 4 FIGURE Circ-UBAP2 modulated glioma cell behaviors via targeting miR-1205 or miR-382. A172 and U251 cells were transfected with si-NC, si-circ-UBAP2, si-circ-UBAP2+anti-miR-NC, si-circ-UBAP2+anti-miR-1205, or si-circ-UBAP2+anti-miR-382. (A, B) miR-1205 and miR-382 expression were assessed using qRT-PCR. (C) Cell viability was gauged using CCK-8 assay. (D) Colony formation was evaluated using colony formation assay. (E) Cell apoptosis was detected using flow cytometry. (F, G) Cell migration and invasion were gauged using transwell assay. (H) Cell migration was monitored using wound-healing assay. (I, J) The levels of CyclinD1 and MMP9 by western blot. * p < 0.05, ** p < 0.01, *** p < 0.001 or **** p < 0.0001
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- 6 FIGURE miR-1205 overexpression regulated cell behaviors by downregulating GPRC5A. A172 and U251 cells were transfected with miR-NC mimic, miR-1205 mimic, miR-1205 mimic+pcDNA, or miR-1205 mimic+GPRC5A (GPRC5A overexpressing plasmid). (A) GPRC5A protein expression was assessed using western blot. (B) Cell viability was gauged using CCK-8 assay. (C) Colony formation was evaluated using colony formation assay. (D) Cell apoptosis was detected using flow cytometry. (E, F) Cell migration and invasion were gauged using transwell assay. (G) Cell migration was monitored using wound-healing assay. (H, I) The levels of CyclinD1 and MMP9 by western blot. * p < 0.05, *** p < 0.001, or **** p < 0.0001
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- 7 FIGURE The regulation of miR-382 on cell proliferation, migration, invasion, and apoptosis was mediated by GPRC5A. A172 and U251 cells were transfected with miR-NC mimic, miR-382 mimic, miR-382 mimic+pcDNA, or miR-382 mimic+GPRC5A (GPRC5A overexpressing plasmid). (A) GPRC5A protein expression was assessed using western blot. (B) Cell viability was gauged using CCK-8 assay. (C) Colony formation was evaluated using colony formation assay. (D) Cell apoptosis was detected using flow cytometry. (E, F) Cell migration and invasion were gauged using a transwell assay. (G) Cell migration was monitored using a wound-healing assay. (H, I) The levels of CyclinD1 and MMP9 by western blot. * p < 0.05, ** p < 0.01, *** p < 0.001, or **** p < 0.0001
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- 9 FIGURE Circ-UBAP2 silencing repressed tumor growth in vivo. sh-circ-UBAP2-, sh-circ-UBAP2#1-transduced, or sh-NC-infected U251 cells were implanted into the nude mice ( n = 6). (A) Growth curves of the xenograft tissues. (B) Representative pictures and average weight of the tumors tissues. The levels of circ-UBAP2, miR-1205, and miR-382 were measured using qRT-PCR (C), and GPRC5A protein expression (D) and CyclinD1 and MMP9 levels (E) by western blot in the excised tumor tissues. * p < 0.05, ** p < 0.01, *** p < 0.001, or **** p < 0.0001
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- Fig. 6 Reduced cell proliferation in Nrf1 f/f ;Six3-Cre retina. ( a , b ) BrdU labeling of E13.5 wildtype ( a ) and Nrf1 f/f ;Six3-Cre ( b ) retinal sections. ( c ) The number of BrdU+ cells in wildtype and Nrf1 f/f ;Six3-Cre sections. ( d , e ) E13.5 wildtype and Nrf1 f/f ;Six3-Cre retinal sections labeled with anti-PH3 antibody. ( f ) The number of PH3+ cells in wildtype and Nrf1 f/f ;Six3-Cre retinal sections. ( g , h ) Immunostaining of E13.5 wildtype and Nrf1 f/f ;Six3-Cre retinal sections with anti-Ccnd1 antibody. ( i ) qRT-PCR analysis of Ccnd1 and Gli1 in E13.5 WT and Nrf1 f/f ;Six3-Cre retinas. Scale 50 mum. WT: wildtype
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- Figure 4. CDCA4 affected cell cycle and AKT/mTOR signaling pathway. (a-b) GSEA was utilized to identify the relative signaling pathway associated with high CDCA4 expression. (c-f) The effects of CDCA4-knockdown (c-d) and -overexpression (e-f) on the AKT/mTOR relative markers and Cyclin D1 protein were evaluated using western blot analysis. (d) Quantification of c. (f) Quantification of e. ** p < 0.01 vs . si-NC or vector group.
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- Figure 2 Representation of the final score estimation in the immunoexpression profiling: ( A ) Results of the immunoexpression profiling classified in absent or low staining and moderate or strong staining categories for p16, p21, Bcl-2, Raf kinase inhibitor protein (RKIP), and cyclin-dependent kinase D1 (Cyclin D1); and ( B ) Median size of the appendiceal NENs according to the molecular markers' staining score, (bars with s.e.m., * p < 0.05).
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- Figure 5. Effects of knockdown or overexpression of ADAM29 on proliferation- and motion-related proteins. Western blot assay was adopted to determine the effect of ADAM29 knockdown (a) or overexpression (b) on the level of Cyclin D1, PCNA, MMP9 and Snail. ** p < 0.01 vs. si-con group or vector group.
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- Negative correlation between ecto-enzymes and CCND1 expression in CRC. ( A ) IHC staining of human normal colon (n = 40) and colon adenocarcinoma (n = 64) specimens in a tissue microarray for CCND1 and CD163 (a macrophage marker). ( B ) Relative intensities of CCND1 staining in the lamina propria of a normal and cancerous colon. ** P < .01 (unpaired t test). ( C ) Correlation analysis of NT5E and CCND1 expression in the TCGA colorectal adenocarcinoma dataset. *** P < .001 (Student t test).
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- Figure 1 Cyclin D1/CDK4 expression is correlated to the presence of KRAS mutation in lung cancer tumours. A. pRb, CDK4 and cyclin D1 immunoperoxidase nuclear staining in lung adenocarcinoma (ADC, upper panels) and in squamous cell carcinoma (SCC, lower panels). CyclinD1 (panel 1, score of 70%; panel 2, score of 40%), CDK4 (panel 3, score of 50%; panel 4, score of 50%), and pRb (panel 5, score of 10%; panel 6, score of 20%) expression. Bars, 100 um (ADC) and 50 um (SCC). B. Distribution of cyclin D1, CDK4, and pRb staining (percentage of positive cells, Y-axis) according to the histological subtype of tumours. Statistical analysis was carried out using Mann-Whitney's U -test. C. Cyclin D1 expression according to KRAS mutation status of tumours. Statistical analysis was performed using Fisher's exact test. Missing data were excluded from the analysis.
