Antibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Western blot [1]
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- Product number
- ABIN2839761 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (pSer395) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer395
- Antibody clone number
- RB07988
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
Lu X, Ma O, Nguyen TA, Jones SN, Oren M, Donehower LA
Cancer cell 2007 Oct;12(4):342-54
Cancer cell 2007 Oct;12(4):342-54
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
Maya R, Balass M, Kim ST, Shkedy D, Leal JF, Shifman O, Moas M, Buschmann T, Ronai Z, Shiloh Y, Kastan MB, Katzir E, Oren M
Genes & development 2001 May 1;15(9):1067-77
Genes & development 2001 May 1;15(9):1067-77
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- WB