ABIN356776

antibody from antibodies-online

Targeting: MDM2 HDM2, MGC5370

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN356776

Provider

antibodies-online

Product name

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) antibody

Antibody type

Polyclonal

Description

Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1.

Burch LR, Scott M, Pohler E, Meek D, Hupp T
Journal of molecular biology 2004 Mar 12;337(1):115-28

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Regulation of p53 by Mdm2: fate is in the numbers.

Shmueli A, Oren M
Molecular cell 2004 Jan 16;13(1):4-5

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p53 activation in chronic radiation-treated breast cancer cells: regulation of MDM2/p14ARF.

Xia L, Paik A, Li JJ
Cancer research 2004 Jan 1;64(1):221-8

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Mdm2 mRNA expression in salivary gland tumour cell lines.

Mantesso A, Loducca SV, Bendit I, Garicochea B, Nunes FD, de Araújo VC
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2004 Feb;33(2):96-101

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Binding of p53-derived ligands to MDM2 induces a variety of long range conformational changes.

Schon O, Friedler A, Freund S, Fersht AR
Journal of molecular biology 2004 Feb 6;336(1):197-202