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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- ABIN363126 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 164-168) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around AA 164-168 (A-I-S-E-T) derived from Human MDM2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen .
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 164-168
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus.
p300/MDM2 complexes participate in MDM2-mediated p53 degradation.
Mdm2 promotes the rapid degradation of p53.
Mayo LD, Donner DB
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 25;98(20):11598-603
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 25;98(20):11598-603
p300/MDM2 complexes participate in MDM2-mediated p53 degradation.
Grossman SR, Perez M, Kung AL, Joseph M, Mansur C, Xiao ZX, Kumar S, Howley PM, Livingston DM
Molecular cell 1998 Oct;2(4):405-15
Molecular cell 1998 Oct;2(4):405-15
Mdm2 promotes the rapid degradation of p53.
Haupt Y, Maya R, Kazaz A, Oren M
Nature 1997 May 15;387(6630):296-9
Nature 1997 May 15;387(6630):296-9
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