27883-1-AP

antibody from Proteintech Group

Targeting: MDM2 HDM2, MGC5370

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

27883-1-AP

Provider

Proteintech Group

Product name

MDM2 antibody

Antibody type

Polyclonal

Description

KD/KO validated MDM2 antibody (Cat. #27883-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human and has been validated for the following applications: FC, WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

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MDM2 promotes cancer cell survival through regulating the expression of HIF-1α and pVHL in retinoblastoma.

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Structure-based discovery of novel α-aminoketone derivatives as dual p53-MDM2/MDMX inhibitors for the treatment of cancer.

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European journal of medicinal chemistry 2023 Apr 5;252:115282

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ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice.

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USP49-Mediated Histone H2B Deubiquitination Regulates HCT116 Cell Proliferation through MDM2-p53 Axis.

Shi L, Shen X, Shen Y
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Design, synthesis and biological evaluation of novel pyrrolidone-based derivatives as potent p53-MDM2 inhibitors.

Si D, Luo H, Zhang X, Yang K, Wen H, Li W, Liu J
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