FNab05077

antibody from FineTest Biotech

Targeting: MDM2 HDM2, MGC5370

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ELISA

Immunocytochemistry

Immunohistochemistry

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Validation data

Product number: FNab05077 - Provider product page
Provider: FineTest Biotech
Product name: MDM2 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: Mdm2 p53 binding protein homolog ( Mouse )
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)

MDM2 protein structure - FNab05077 shown in red.