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- Antigen structure
- References [3]
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- Product number
- ABIN358505 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (pSer395) antibody
- Antibody type
- Polyclonal
- Description
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer395
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
Characterization of two peptide epitopes on Mdm2 oncoprotein that affect p53 degradation.
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
Lu X, Ma O, Nguyen TA, Jones SN, Oren M, Donehower LA
Cancer cell 2007 Oct;12(4):342-54
Cancer cell 2007 Oct;12(4):342-54
Characterization of two peptide epitopes on Mdm2 oncoprotein that affect p53 degradation.
Balass M, Kalef E, Maya R, Wilder S, Oren M, Katchalski-Katzir E
Peptides 2002 Oct;23(10):1719-25
Peptides 2002 Oct;23(10):1719-25
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
Maya R, Balass M, Kim ST, Shkedy D, Leal JF, Shifman O, Moas M, Buschmann T, Ronai Z, Shiloh Y, Kastan MB, Katzir E, Oren M
Genes & development 2001 May 1;15(9):1067-77
Genes & development 2001 May 1;15(9):1067-77
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