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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- ABIN363147 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 1 (CHEK1) (pSer280) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer280 (V-T-S (p) -G-G) derived from Human Chk1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer280
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Inhibition of Chk1 by activated PKB/Akt.
The DNA damage checkpoint in embryonic cell cycles is dependent on the DNA-to-cytoplasmic ratio.
A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle.
King FW, Skeen J, Hay N, Shtivelman E
Cell cycle (Georgetown, Tex.) 2004 May;3(5):634-7
Cell cycle (Georgetown, Tex.) 2004 May;3(5):634-7
The DNA damage checkpoint in embryonic cell cycles is dependent on the DNA-to-cytoplasmic ratio.
Conn CW, Lewellyn AL, Maller JL
Developmental cell 2004 Aug;7(2):275-81
Developmental cell 2004 Aug;7(2):275-81
A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle.
Shtivelman E, Sussman J, Stokoe D
Current biology : CB 2002 Jun 4;12(11):919-24
Current biology : CB 2002 Jun 4;12(11):919-24
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