CHEK1

gene product
CHK1
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
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1648 antibodies from 42 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
673 antibodies
Novus Biologicals
20 antibodies
Cell Signaling Technology, Inc
11 antibodies
GeneTex
21 antibodies
Abnova Corporation
23 antibodies
Bethyl Laboratories
5 antibodies
Biorbyt
98 antibodies