CHEK1

gene product
CHK1
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
1806 antibodies from 46 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Novus Biologicals
19 antibodies
antibodies-online
673 antibodies
GeneTex
21 antibodies
Abnova Corporation
23 antibodies
Proteintech Group
4 antibodies
Invitrogen Antibodies
43 antibodies
Cell Signaling Technology, Inc
11 antibodies
Bethyl Laboratories
5 antibodies
OriGene
51 antibodies
LifeSpan BioSciences, Inc.
229 antibodies
Biorbyt
103 antibodies
Affinity Biosciences
11 antibodies
Acris Antibodies GmbH
41 antibodies
Aviva Systems Biology
26 antibodies
NovoPro Bioscience Inc.
11 antibodies
Boster Biological Technology
8 antibodies
HUABIO Research
2 antibodies
Signalway Antibody LLC
2 antibodies
R&D Systems
3 antibodies
Bioworld Technology, Inc
10 antibodies
Enzo Life Sciences
2 antibodies
St John's Laboratory
19 antibodies
Abgent
17 antibodies
Arigo
2 antibodies
ProSci
10 antibodies
Abbkine Scientific Co.Ltd.
12 antibodies
RabMAbs
14 antibodies
Antibodies.com
1 antibody
NSJ Bioreagents
8 antibodies
Creative Biolabs
29 antibodies
Abbexa
43 antibodies
Creative Diagnostics
8 antibodies
Atlas Antibodies
1 antibody
United States Biological
225 antibodies
MyBioSource
26 antibodies
Abiocode, Inc.
1 antibody
Leading Biology
9 antibodies
GenWay
9 antibodies
Sigma-Aldrich
4 antibodies
EMD Millipore
2 antibodies
Everest Biotech
1 antibody
Exalpha Biologicals, Inc.
1 antibody
RayBiotech, Inc.
1 antibody
Abbiotec
1 antibody
CPTAC
5 antibodies