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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations [0]
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- Product number
- ABIN965880 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 1 (CHEK1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human CHEK1(Serine/threonine-protein kinase Chk1)
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 0.1mg
- Storage
- Store at -20°C.
Submitted references Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress.
Chaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperones.
Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase.
Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway.
Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe.
Analysis of the candidate target genes for mutation in microsatellite instability-positive cancers of the colorectum, stomach, and endometrium.
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.
Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes.
Rodriguez R, Meuth M
Molecular biology of the cell 2006 Jan;17(1):402-12
Molecular biology of the cell 2006 Jan;17(1):402-12
Chaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperones.
Arlander SJ, Felts SJ, Wagner JM, Stensgard B, Toft DO, Karnitz LM
The Journal of biological chemistry 2006 Feb 3;281(5):2989-98
The Journal of biological chemistry 2006 Feb 3;281(5):2989-98
Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase.
Petermann E, Maya-Mendoza A, Zachos G, Gillespie DA, Jackson DA, Caldecott KW
Molecular and cellular biology 2006 Apr;26(8):3319-26
Molecular and cellular biology 2006 Apr;26(8):3319-26
Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway.
Clarke CA, Bennett LN, Clarke PR
The Journal of biological chemistry 2005 Oct 21;280(42):35337-45
The Journal of biological chemistry 2005 Oct 21;280(42):35337-45
Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe.
Niida H, Tsuge S, Katsuno Y, Konishi A, Takeda N, Nakanishi M
The Journal of biological chemistry 2005 Nov 25;280(47):39246-52
The Journal of biological chemistry 2005 Nov 25;280(47):39246-52
Analysis of the candidate target genes for mutation in microsatellite instability-positive cancers of the colorectum, stomach, and endometrium.
Semba S, Ouyang H, Han SY, Kato Y, Horii A
International journal of oncology 2000 Apr;16(4):731-7
International journal of oncology 2000 Apr;16(4):731-7
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.
Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ
Science (New York, N.Y.) 1997 Sep 5;277(5331):1497-501
Science (New York, N.Y.) 1997 Sep 5;277(5331):1497-501
Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes.
Flaggs G, Plug AW, Dunks KM, Mundt KE, Ford JC, Quiggle MR, Taylor EM, Westphal CH, Ashley T, Hoekstra MF, Carr AM
Current biology : CB 1997 Dec 1;7(12):977-86
Current biology : CB 1997 Dec 1;7(12):977-86
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